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You searched for: Subject animal injuries Remove constraint Subject: animal injuries Subject cerebrospinal fluid Remove constraint Subject: cerebrospinal fluid
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1. Acute Intervertebral Disc Extrusion in a Cat: Clinical and MRI Findings

Author:
D Lu; CR Lamb; K Wesselingh; MP Targett
Source:
Journal of feline medicine and surgery v.4 no.1 pp. 65-68
ISSN:
1098-612X
Subject:
cats; intervertebral disks; paresis; spinal cord; image analysis; animal injuries; cerebrospinal fluid; case studies; magnetic resonance imaging
Abstract:
... A 5 year old, neutered male, domestic shorthaired cat had acute left hemiparesis and Horner's syndrome. Magnetic resonance imaging (MRI) revealed a loss of the normal signal from the nucleus pulposus of the intervertebral disc at C3/4, narrowing of the ventral subarachnoid space and slight dorsal displacement of the spinal cord and a focal hyperintense lesion affecting the left side of the spinal ...
DOI:
10.1053/jfms.2001.0150
PubMed:
11869056

2. Application of Autologous Peripheral Blood Mononuclear Cells into the Area of Spinal Cord Injury in a Subacute Period: A Feasibility Study in Pigs

Author:
Iliya Shulman; Sergei Ogurcov; Alexander Kostennikov; Alexander Rogozin; Ekaterina Garanina; Galina Masgutova; Mikhail Sergeev; Albert Rizvanov; Yana Mukhamedshina
Source:
Biology 2021 v.10 no.2 pp. -
ISSN:
2079-7737
Subject:
animal injuries; blood serum; cerebrospinal fluid; cytokines; feasibility studies; fibrin; models; spinal cord; swine; therapeutics
Abstract:
... Peripheral blood presents an available source of cells for both fundamental research and clinical use. In our study, we have evaluated the therapeutic potential of peripheral blood mononuclear cells (PBMCs) excluding the preliminary sorting or mobilization of peripheral blood stem cells. We have evaluated the regenerative potential of PBMCs embedded into a fibrin matrix (FM) in a model of pig spin ...
DOI:
10.3390/biology10020087

3. CD8 T cell-derived perforin aggravates secondary spinal cord injury through destroying the blood-spinal cord barrier

Author:
Zhaoxiang Liu; Hua Zhang; Hong Xia; Baocheng Wang; Renwen Zhang; Qun Zeng; Lingzhi Guo; Kui Shen; BaTa Wang; Yanheng Zhong; Zhizhong Li; Guodong Sun
Source:
Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
ISSN:
0006-291X
Subject:
CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
Abstract:
... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...
DOI:
10.1016/j.bbrc.2019.03.002

4. Chronic Traumatic Brain Injury in a Dog

Author:
Laurent, S.; Thibaud, J.L.; Hordeaux, J.; Reyes-Gomez, E.; Delisle, F.; Blot, S.; Colle, M.A.
Source:
Journal of comparative pathology 2010 v.143 no.1 pp. 75-80
ISSN:
0021-9975
Subject:
animal injuries; neurons; dog diseases; necrosis; dogs; animal welfare; hemorrhage; cerebrospinal fluid; neutrophils; brain damage; cerebral cortex; necropsy; computed tomography; histopathology; signs and symptoms (animals and humans)
DOI:
10.1016/j.jcpa.2009.12.008
PubMed:
20106486

5. Clinical and Histopathological Findings of Hemorrhagic Progressive Myelomalacia after Lumbar Tap in 2 Dogs: Case Report

Author:
Marcelo Luís Schwab; Dênis Antonio Ferrarin; Mathias Reginatto Wrzesinski; Júlia da Silva Rauber; Angel Ripplinger; Eryca Ceolin Lamego; Mariana Martins Flores; Alexandre Mazzanti
Source:
Topics in companion animal medicine 2022 v.50 pp. 100681
ISSN:
1938-9736
Subject:
Bichon Frise; anesthesia; animal injuries; astrocytoma; case studies; cerebrospinal fluid; coma; dogs; epilepsy; histopathology; medicine; necropsy; pets
Abstract:
... Bichon frise (1) and Boxer (2), both with epileptic seizures, underwent lumbar taps for cerebrospinal fluid collection. After the procedure, the first dog became paraplegic, and the second dog did not recover from anesthesia and remained in a coma. Both dogs were euthanatized 12 h after the examination. The dogs were diagnosed with idiopathic epilepsy and fibrillar astrocytoma, respectively, after ...
DOI:
10.1016/j.tcam.2022.100681

6. Comparative analysis of cytokine gene expression in cerebrospinal fluid of horses without neurologic signs or with selected neurologic disorders

Author:
Pusterla, N.; Wilson, W.D.; Conrad, P.A.; Mapes, S.; Leutenegger, C.M.
Source:
American journal of veterinary research 2006 v.67 no.8 pp. 1433-1437
ISSN:
0002-9645
Subject:
vertebrate viruses; animal injuries; complementary DNA; interleukins; equine protozoal myeloencephalitis; Sarcocystis neurona; West Nile virus; cerebrospinal fluid; gene expression; polymerase chain reaction; tumor necrosis factor-alpha; genes; transforming growth factor beta; spinal cord; viral encephalitis; horses; interferons
DOI:
10.2460/ajvr.67.8.1433
PubMed:
16881858

7. Data on the recovery of glycinergic neurons after spinal cord injury in lampreys

Author:
Silvia María Valle-Maroto; Antón Barreiro-Iglesias; Blanca Fernández-López; María Celina Rodicio
Source:
Data in Brief 2020 v.28 pp. 105092
ISSN:
2352-3409
Subject:
animal injuries; animals; cerebrospinal fluid; immune response; immunohistochemistry; larvae; locomotion; spinal cord
Abstract:
... We used immunohistochemical methods to quantify changes in the number of glycine-immunoreactive neurons of the dorsomedial, lateral and cerebrospinal fluid contacting cell populations of the spinal cord of larval sea lampreys after a complete spinal cord injury. The data presented here are quantifications of the number of glycine-immunoreactive neurons located in the rostral and caudal stumps of t ...
DOI:
10.1016/j.dib.2019.105092

8. Gold nanodots with stable red fluorescence for rapid dual-mode imaging of spinal cord and injury monitoring

Author:
Yangliu Lin; Yueqi Zhao; Zhe Yang; Zhubin Shen; Junran Ke; Fei Yin; Linan Fang; Andrei V. Zvyagin; Bai Yang; Quan Lin
Source:
Talanta 2022 v.241 pp. 123241
ISSN:
0039-9140
Subject:
animal injuries; biocompatibility; bioimaging; cerebrospinal fluid; fluorescence; fluorescent dyes; glutathione; iodine; ischemia; necrosis; pain; paralysis; photoluminescence; prognosis; spinal cord; surgery; toxicity; water solubility
Abstract:
... Spinal cord injury is one of the most devastating complications of spinal surgery, often resulting in numbness, pain or paralysis. Minor injuries in the spinal cord are hard to be identified and existing imaging modalities are unable to provide intraoperative monitoring. Monitoring pathological change at the site of injury is a key factor in staging and treatment decision making as well as prognos ...
DOI:
10.1016/j.talanta.2022.123241

9. Iatrogenic brainstem injury during cerebellomedullary cistern puncture

Author:
LUJÁN FELIU-PASCUAL, ALEJANDRO; GAROSI, LAURENT; DENNIS, RUTH; PLATT, SIMON
Source:
Veterinary radiology & ultrasound 2008 v.49 no.5 pp. 467-471
ISSN:
1058-8183
Subject:
dogs; central nervous system diseases; diagnostic techniques; cerebrospinal fluid; brain stem; animal injuries; magnetic resonance imaging
Abstract:
... Cerebrospinal fluid collection is fundamental to the investigation of central nervous system disorders although it carries potential risks. Herein we report the clinical signs and magnetic resonance (MR) imaging findings associated with needle injury to the brainstem during cerebellomedullary cistern puncture in four dogs. Three dogs were nonambulatory tetraparetic with cranial nerve deficits and ...
DOI:
10.1111/j.1740-8261.2008.00410.x
PubMed:
18833957

10. Matrix metalloproteinase-9 activity in the cerebrospinal fluid and serum of dogs with acute spinal cord trauma from intervertebral disk disease

Author:
Levine, J.M.; Ruaux, C.G.; Bergman, R.L.; Coates, J.R.; Steiner, J.M.; Williams, D.A.
Source:
American journal of veterinary research 2006 v.67 no.2 pp. 283-287
ISSN:
0002-9645
Subject:
dogs; dog diseases; spinal diseases; spinal cord; intervertebral disks; metalloproteinases; enzyme activity; cerebrospinal fluid; blood serum; disease severity; animal injuries
DOI:
10.2460/ajvr.67.2.283
PubMed:
16454634

11. Real-time assessment of spinal cord microperfusion in a porcine model of ischemia/reperfusion

Author:
Behem Christoph R.; Friedheim Till; Wipper Sabine H.; Pinnschmidt Hans O.; Graessler Michael F.; Gaeth Catharina; Holthusen Hannes; Rapp Adina; Suntrop Timo; Haunschild Josephina; Etz Christian D.; Trepte Constantin J. C.
Source:
Journal of visualized experiments 2020 no.166 pp. e62047
ISSN:
1940-087X
Subject:
animal injuries; animal models; aorta; cerebrospinal fluid; drainage; fluorescence; hemodynamics; histopathology; ischemia; microparticles; oxygen; patients; spinal cord; swine
Abstract:
... Spinal cord injury is a devastating complication of aortic repair. Despite developments for the prevention and treatment of spinal cord injury, its incidence is still considerably high and therefore, influences patient outcome. Microcirculation plays a key role in tissue perfusion and oxygen supply and is often dissociated from macrohemodynamics. Thus, direct evaluation of spinal cord microcircula ...
DOI:
10.3791/62047

12. Single-step functionalization of poly-catecholamine nanofilms for ultra-sensitive immunosensing of ubiquitin carboxyl terminal hydrolase-L1 (UCHL-1) in spinal cord injury

Author:
Sultan Khetani; Vinayaraj Ozhukil Kollath; Erin Eastick; Chantel Debert; Arindom Sen; Kunal Karan; Amir Sanati-Nezhad
Source:
Biosensors & bioelectronics 2019 v.145 pp. 111715
ISSN:
0956-5663
Subject:
animal injuries; antibodies; aqueous solutions; biomarkers; blood serum; brain; cerebrospinal fluid; dopamine; electrodes; gamma-aminobutyric acid; glutamic acid; graphene; immunosensors; moieties; nanosheets; neurotransmitters; norepinephrine; patients; phosphates; polymers; spinal cord; ubiquitin; ubiquitinyl hydrolase 1
Abstract:
... Rapid, selective, and ultra-sensitive detection of brain and spinal cord injury markers in bodily fluids is an unmet clinical need. In this work, Polycatecholamine as a rich source of amine moieties was used for single-step fabrication of ultrasensitive immunosensors for the detection of Ubiquitin carboxyl-terminal hydrolase (UCHL-1) biomarker of brain and spinal cord injuries and address the clin ...
DOI:
10.1016/j.bios.2019.111715

13. The Spinal Ependymal Layer in Health and Disease

Author:
S. A. Moore
Source:
Veterinary pathology v.53 no.4 pp. 746-753
ISSN:
1544-2217
Subject:
animal injuries; animal pathology; brain; cerebrospinal fluid; epithelium; growth factors; heat shock proteins; mechanical damage; neural stem cells; neurodegenerative diseases; neurons; neurophysiology; progeny; researchers; spinal cord; tumor necrosis factors
Abstract:
... Ependymal cells are epithelial support cells that line the central canal and ventricular cavities of the central nervous system, providing the interface between the cerebrospinal fluid and the parenchyma of the brain and spinal cord. The spinal ependymal layer (SEL) is composed of 3 main cell types: tanycytes, ependymocytes, and cerebrospinal fluid–contacting neurons. A fourth cell type, termed th ...
DOI:
10.1177/0300985815618438

14. The prognostic value of cerebrospinal fluid characteristics in dogs without deep pain perception due to thoracolumbar disc herniation

Author:
Y. Chamisha; I. Aroch; S. Kuzi; I. Srugo; T. Bdolah-Abram; O. Chai; M.M. Christopher; Y. Merbl; K. Rothwell; M.H. Shamir
Source:
Research in veterinary science 2015 v.100 pp. 189-196
ISSN:
0034-5288
Subject:
animal injuries; cerebrospinal fluid; dogs; intervertebral disks; macrophages; monocytes; pain; prediction; prognosis; spinal cord
Abstract:
... Providing a pre-operative prognosis for dogs presented with absent deep pain perception (DPP) is extremely challenging, as the overall recovery rates widely vary. This study assesses the possible correlation between the severity of spinal cord injury and CSF cytology in 31 paraplegic dogs presented with absent DPP due to acute thoracolumbar intervertebral disc herniation (TL-IVDH). All dogs underw ...
DOI:
10.1016/j.rvsc.2015.03.017