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... The skeletal muscle mass reduces 30–60% after spinal cord injury, this is mostly due to protein degradation through ubiquitin–proteasome system. In this work, we propose that the flavanol (−)-epicatechin, due its widespread biological effects on muscle health, can prevent muscle mass decrease after spinal cord injury. Thirty-six female Long Evans rats were randomized into 5 groups: (1) Spinal cord ...
... Ice recrystallization during thawing after cryopreservation results in extensive cellular damage that ultimately leads to cell death and decreased cell viabilities. This is a significant problem particularly with cryopreserved cells utilized in various regenerative medicine therapies. Given the success of these therapies to treat spinal cord injury, cartilage lesions, and cardiac disease, the deve ...
... The lack of disease-modifying pharmacological agents for effective treatment of multiple sclerosis (MS) still represents a large and urgent unmet medical need. Our previous studies showed that ligands to type 2 imidazoline receptors (I₂R) were effective in protecting spinal cord injury caused by experimental autoimmune encephalomyelitis (EAE), a mouse model of MS. In this study, we further examine ...
... Three-dimensional (3D) bioprinting has emerged as a promising approach to fabricate living neural constructs with anatomically accurate complex geometries and spatial distributions of neural stem cells (NSCs) for spinal cord injury (SCI) repair. The NSC-laden 3D bioprinting, however, still faces some big challenges, such as cumbersome printing process, poor cell viability, and minimal cell-materia ...
... Although traditional 3D scaffolds or biomimetic hydrogels have been used for tissue engineering and regenerative medicine, soft tissue microenvironment usually has a highly anisotropic structure and a dynamically controllable deformation with various biomolecule distribution. In this study, we developed a hierarchical hybrid gelatin methacrylate-microcapsule hydrogel (HGMH) with Neurotrophin-3(NT- ...
... BACKGROUND: Despite its importance, there is no agreed definition of recovery of ambulation in dogs with spinal cord injury. OBJECTIVES: To validate a new walking test in dogs recovering from thoracolumbar spinal cord injury. ANIMALS: Two hundred twenty‐four dogs weighing <20 kg: 120 normally ambulatory dogs, plus 104 dogs undergoing decompressive surgery for acute thoracolumbar intervertebral dis ...
... The ability to induce a hypometabolic state holds immense clinical promise since it serves as a means of lowering tissue energy needs and reducing ischemia damage; however, is also associated with many adverse effects in humans and most mammals. Nonetheless, hypometabolic states produced by drug administration or chilling have been applied for treatment of stroke, heart attack, multiple organ fail ...
... High spinal cord injuries (SCI) induce the deafferentation of phrenic motoneurons, leading to permanent diaphragm paralysis. This involves secondary injury associated with pathologic and inflammatory processes at the site of injury, and at the level of phrenic motoneurons. In the present study, we evaluated the antioxidant response in phrenic motoneurons involving the AMPK-Nrf2 signaling pathway f ...
animal injuries; animals; clinical examination; curriculum; medical education; medicine; monitoring; patients; pneumothorax; prognosis; surgeons; terminology; therapeutics; ultrasonics; universities; veterinarians; United States
Abstract:
... Objectives - To review the nonradiologist use of ultrasound (US) in the setting of emergency and critical care, the development, clinical applications, and standardization of veterinary abdominal and thoracic focused assessment with sonography for trauma (FAST) techniques. Etiology - Since the 1990s, the 4-point FAST US technique has been used for injury surveillance in people with blunt and penet ...
animal injuries; breeding sites; death; emaciation; endangered species; habitats; heavy metals; ingestion; kidneys; lead; lead poisoning; liver; meat carcasses; mortality; necropsy; pollutants; stomach; surveys; China; Mongolia; South Korea
Abstract:
... Globally threatened Cinereous vultures (Aegypius monachus) regularly over-winter in South Korea, and they have frequently been found dead in their natural habitats. As one possible factor for their mortality, we investigated tissues for heavy metal contaminants along with necropsies on 20 dead Cinereous vultures. Severe emaciation was found in the survey, being associated with 19 of the deaths. Tw ...
... Among the cellular processes that follow injury to the central nervous system, glial scar formation is thought to be one of the major factors that prevent regeneration. In regeneration-competent organisms, glial scar formation has been a matter of controversy. We addressed this issue by examining the glial population after spinal cord injury in a model of regeneration competency, the knifefish Apt ...
animal injuries; biomarkers; kidneys; liquid chromatography; monitoring; peptides; tandem mass spectrometry; urine
Abstract:
... Podocalyxin is a protein present in specialized glomerulus cells called podocytes and may be released in the urine in case of kidney injury. In this context, its quantification could be of great interest in order to monitor glomerular injury. Liquid chromatography tandem mass spectrometry (LC–MS/MS), in selected reaction monitoring (SRM) mode, has been demonstrated as a powerful technique that can ...
infection; drug therapy; lesions (animal); animal injuries; neoplasms; dog diseases; gingiva; dogs; drug toxicity; antineoplastic agents; drug injection; adverse effects; swelling (physiological)
Abstract:
... Acanthomatous ameloblastoma (AA) is a benign gingival tumour that often invades bone. This retrospective study evaluated the efficacy of intralesional (IL) bleomycin as a treatment for AA. Six dogs received weekly or bimonthly IL bleomycin injections (dose range, 10-20 U m⁻²). A seventh dog presented with advanced, nonresectable AA was treated palliatively. One to sixteen treatments were administe ...
animal injuries; appetite; energy expenditure; energy intake; ghrelin; glucagon-like peptide 1; lean body mass; obesity; risk; satiety
Abstract:
... In persons with spinal cord injury (SCI), reduced fat-free mass and movement-related energy expenditure increase obesity risk. Although plausible mechanisms exist, it remains unknown whether impaired appetite regulation potentiates obesity risk in SCI. This study compared postprandial responses of appetite-related hormones, appetite perceptions and the sensitivity of appetite to covert preload ene ...
... The calliphorid fly, Lucilia cuprina (Wiedemann), is known to cause serious malign myiasis in animals, whereas its sibling species Lucilia sericata (Meigen) is commonly a carrion breeder and is used in maggot debridement therapy (MDT). The current study reports an accidental involvement of L. cuprina in MDT in Alexandria, Egypt, that has proved to be safe and effective. In November 2008, the labor ...
... Objective-To determine the combination of ground reaction forces (GRFs) that best discriminates between lame and non-lame dogs. To compare the sensitivity of force platform gait analysis and visual observation at detecting gait abnormalities in Labradors after surgery for rupture of the cranial cruciate ligament (CCL). Animals-All dogs were adult Labrador Retrievers: 17 free of orthopedic and neur ...
... Spinal cord injury (SCI) is a traumatic injury to the central nervous system (CNS) with a high rate of disability and a low capability of self-recovery. Phosphatase and tensin homolog (PTEN) inhibition by pharmacological blockade with bisperoxovanadium (pic) (bpV(pic)) has been reported to increase AKT/mTOR activity and induce robust axonal elongation and regeneration. However, the therapeutic eff ...
... Sponges of the genus Aplysina accumulate brominated isoxazoline alkaloids in concentrations that sometimes exceed 10% of their dry weight. We previously reported a decrease in concentrations of these compounds and a concomitant increase in concentrations of the monocyclic nitrogenous compounds aeroplysinin-1 and dienone in Aplysina aerophoba following injury of the sponge tissue. Further investiga ...
... Zebrafish is an excellent model to study the mechanisms underlying successful central nervous system (CNS) regeneration. Previous study shows that activating transcription factor 3 (ATF3) promotes neurite outgrowth and is involved in optic nerve regeneration in zebrafish. Here, we used zebrafish model to investigate the role of ATF3 in regeneration following spinal cord injury (SCI). Quantitative ...
... In healthy adults, activation of γ-aminobutyric acid (GABA) A and glycine receptors inhibits neurons as a result of low intracellular chloride concentration ([Cl –] ᵢ), which is maintained by the potassium-chloride cotransporter KCC2. A reduction of KCC2 expression or function is implicated in the pathogenesis of several neurological disorders, including spasticity and chronic pain following spina ...
... Purinergic ionotropic P2X7 receptors (P2X7Rs) are closely associated with excitotoxicity and nociception. Inhibition of P2X7R activation has been considered as a potentially useful strategy to improve recovery from spinal cord injury and reduce inflammatory damage to trauma. The physiological functions of P2X7Rs, however, are poorly understood, even though such information is essential for making ...
... We established transgenic Drosophila strains in which the lacZ gene was expressed under the control of the 5'-upstream regulatory region of the Sarcophaga lectin gene promoter (3.1 kbp). The reporter gene was expressed in the fat bodies of the transgenic larvae when they were immunized by body pricking or treatment with Escherichia coli, which was the same as the Sarcophaga lectin gene expression ...
cats; intervertebral disks; paresis; spinal cord; image analysis; animal injuries; cerebrospinal fluid; case studies; magnetic resonance imaging
Abstract:
... A 5 year old, neutered male, domestic shorthaired cat had acute left hemiparesis and Horner's syndrome. Magnetic resonance imaging (MRI) revealed a loss of the normal signal from the nucleus pulposus of the intervertebral disc at C3/4, narrowing of the ventral subarachnoid space and slight dorsal displacement of the spinal cord and a focal hyperintense lesion affecting the left side of the spinal ...
blindness; case studies; dogs; dog diseases; eyes; eye diseases; explosions; hemorrhage; vision; animal injuries
Abstract:
... A 3-year-old, intact male, mixed breed dog was presented with a complaint of acute blindness. Ten days previously, the area where the dog was walking came under a rocket attack, and a rocket landed and exploded 300 meters away from the dog. Physical examination was unremarkable. Ophthalmoscopic examination revealed posterior segment fibrin clots and extensive vitreal hemorrhage in the right eye. A ...
animal injuries; radiography; vertebrae; parents; dogs; German Shepherd; necropsy; heritability; case studies; spinal cord; Poodle (dog breed)
Abstract:
... BACKGROUND: Non-ambulatory tetraparesis with an absence of the dens of C2 (axis) has not previously been reported in large breed dogs. An absence or hypoplasia of the dens has been reported in both small, medium and large breed dogs, but not in closely related animals. METHODS: Two young large-breed dogs (a German shepherd and a Standard poodle) both with an acute onset of non-ambulatory tetrapare ...
animal injuries; wood; dogs; surgery; paresis; branches; case studies
Abstract:
... A three‐year‐old male neutered crossbred dog was referred for investigation of acute onset quadriparesis, which had occurred following an oropharyngeal stick injury. Myelography revealed a right‐sided extradural lesion overlying the C5/6 intervertebral disc space. A dorsolateral hemilaminectomy was performed at this site and two fragments of wood were removed from the vertebral canal adjacent to t ...
... Acute phase proteins (APPs) have been used as biomarkers of inflammation, infection and trauma for decades in human medicine but have been relatively under-utilised in the context of veterinary medicine. However, significant progress has been made in the detection, measurement and application of APPs as biomarkers in both companion and farm animal medicine over recent years. In the dog, C-reactive ...
... PRACTICAL RELEVANCE: Acute spinal conditions are a common emergency presentation in general veterinary practice and have the potential to cause devastating spinal cord injury (SCI) and consequent severe neurological deficits. SCI can be divided into two subgroups: exogenous SCI (vertebral fracture and/or luxation/subluxation) and endogenous SCI (intervertebral disc extrusion and ischaemic myelopat ...
... Inflammation, including microglial activation in the CNS, is an important hallmark in many neurodegenerative diseases. Microglial stimuli not only impact the brain microenvironment by production and release of cytokines and chemokines, but also influence the activity of bone marrow derived cells and blood born macrophage populations. In many diseases including brain disorders and spinal cord injur ...
... Garlic has been used as a food as well as a component of traditional medicine. Aged garlic extract (AGE) is claimed to promote human health through antioxidant/anti-inflammatory activities with neuroprotective effects. We evaluated the possible beneficial effect of AGE neurologically, pathologically, ultrastructurally, and biochemically in a spinal cord ischemia–reperfusion (I/R) model of rats. Tw ...
Hispanics; acculturation; agricultural health and safety; agromedicine; animal injuries; cutting; farm labor; household income; immigration; males; risk; surveys; vehicles (equipment); California
Abstract:
... The authors report here results from the first follow-up survey of the Mexican Immigration to California: Agricultural Safety and Acculturation (MICASA) cohort of community-dwelling immigrant Hispanic farm workers in California's Central Valley. Among 560 participants the authors observed cumulative 1-year injury incidence of 6.6% (all injuries) and 4.3% (agricultural injuries). Increased prospect ...
accidents; agricultural education; agricultural industry; agricultural machinery and equipment; agrochemicals; allergenicity; amputation; animal injuries; control methods; cutting; developed countries; developing countries; draft animals; economic costs; farm labor; farming systems; hand tools; income; microorganisms; occupational health and safety; pain; pest control; pesticides; poisoning; respiratory system; risk; spinal cord; surveys; tractors
Abstract:
... This paper contains a literature review of the occupational injuries and ill-health in agriculture world-wide and a survey of the attempts that have been made to estimate the resulting economic and social costs.Agricultural workers suffer a wide variety of disorders as a result of their occupation. These range from minor (cuts, bruises) to more severe (deep wounds, fractures), permanent (amputatio ...
... A population-based, cross-sectional study was conducted to investigate the lifetime agricultural injuries causing traumatic disabilities (referred to as residual injuries) in a simple random sample of 1,000 farm operators in Alabama in 1990. Data were collected by mail questionnaire followed by telephone interviews. The goal of this study was to assess the prevalence, characteristics, and potentia ...
ultrasonography; insect bites and stings; animal injuries; tissue repair; hardness; ultrasonics; leather; product quality; quality control
Abstract:
... Our recent research has shown that besides Acoustic Emission (AE), Airborne Ultrasonics (AU) can also be applied for the nondestructive evaluation (NDE) of leather quality. Implementation of these methods in the manufacturing process could save a considerable amount of money, decrease the use of chemicals, reduce production time, increase the value of the leather and increase quality. Our previous ...
... Albumin plasma concentrations are being used as indicators of nutritional status and hepatic function based on the assumption that plasma levels reflect the rate of albumin synthesis. However, it has been shown that albumin levels are not reliable markers of albumin synthesis under a variety of clinical conditions including inflammation, malnutrition, diabetes mellitus, liver disease, and surgical ...
... Either oriented architecture or viscoelasticity is pivotal to neurogenesis, thus, native neural extracellular matrix derived-hyaluronan hydrogels with nano-orientation and viscoelasticity recapitulated might be instructive for neurogenesis, however it is still unexploited. Herein, based on aldehyde-methacrylate difunctionalized hyaluronan, by integrating imine kinetic modulation and microfluidic b ...
... Neural stem/progenitor cell (NSPC)-based spinal cord injury (SCI) therapy is expected to bridge the lesion site by transplanting exogenous NSPCs for replacement of lost cells. The transplanted NSPCs produce a microenvironment conducive to neuronal regeneration, and ultimately, functional recovery. Although both human fetal brain- and spinal cord- derived NSPCs (hbNSPCs and hscNSPCs, respectively) ...
Huperzia serrata; acetylcholinesterase; alkaloids; analgesic effect; animal injuries; body weight; drug resistance; females; homeostasis; inflammation; interneurons; mosses and liverworts; pain; rats; receptors; sensory neurons; spinal cord
Abstract:
... Diverse mechanisms including activation of NMDA receptors, microglial activation, reactive astrogliosis, loss of descending inhibition, and spasticity are responsible for ∼40% of cases of intractable neuropathic pain after spinal cord injury (SCI). Because conventional treatments blocking individual mechanisms elicit only short-term effectiveness, a multimodal approach with simultaneous actions ag ...
... Allicin, the main biologically active compound derived from garlic, exerts a broad spectrum of pharmacological activities and is considered to have therapeutic potential in many neurological disorders. Using an in vitro spinal cord injury model induced by glutamate treatment, we sought to investigate the neuroprotective effects of allicin in primary cultured spinal cord neurons. We found that alli ...
... Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic (Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S-allylcysteine sulfoxide) is converted to allicin in an enzyme-mediated process catalysed by alliinase. Allicin is hydrophobic in nature, can efficiently cross the cellular membranes and behaves as a reactive sulfur species (R ...
... After spinal cord injury, microglial cells are activated and converted to an M1 phenotype. Emerging evidence supports the hypothesis that glucose reprogramming accompanies microglial activation. What contributes to the activation of microglia and glucose reprogramming, however, remains unclear. In the current study, we investigated the role and underlying mechanism of a-synuclein in regulating the ...
... Dorsal fin damage in salmonid fishes is primarily caused by aggression. While undesirable in fish culture, it can nevertheless be a useful tool to study social interactions in large groups of fish where it is difficult to study the behaviour of known individuals directly. We used low temperature treatment to manipulate the growth rates of juvenile Atlantic salmon (Salmo salar) in the spring and fo ...
adenosine; adenosine triphosphate; animal injuries; anti-inflammatory activity; death; glycosides; in vitro studies; in vivo studies; inflammasomes; lipopolysaccharides; locomotion; membrane potential; mitochondrial membrane; models; neurons; neuroprotective effect; pathogenesis; rats; reactive oxygen species; signal transduction; spinal cord; staining; therapeutics; transcription factor NF-kappa B
Abstract:
... The activation of NLRP3 inflammasome, which initiates an inflammatory cascade and triggers inflammatory death, plays a crucial role in the pathogenesis of spinal cord injury (SCI). Echinacoside (ECH) is a phenylethanoid glycoside possessing prominent anti-inflammatory effects and various neuroprotective properties in the central nervous system, but the effect of ECH on SCI was rarely studied. Ther ...
acidosis; adverse effects; analgesic effect; analgesics; anesthetics; animal injuries; animal welfare; benzocaine; blood; body weight; combination drug therapy; cortisol; depth of anesthesia; farmed fish; ion exchange; margin of safety; medicine; netting; nociception; sedation; slaughter; sorting; stress response; surgery; vaccination; water temperature
Abstract:
... During their life cycle as farmed animals, there are several situations in which fish are subjected to handling and confinement. Netting, weighing, sorting, vaccination, transport and, at the end, slaughter are frequent events under farming conditions. As research subjects, fish may also undergo surgical procedures that range from tagging, sampling and small incisions to invasive procedures. In th ...
... We aimed to investigate the correlation between the Glasgow Coma Scale (GCS), the injury severity score (ISS) and serum levels of trace elements (TE) in severe trauma patients to analyze alteration of the levels of trace elements and serum biochemical indexes in the period of admission from 126 adult cases of severe brain trauma with traffic accidents. Multi-trace elements for patients in the trau ...
animal injuries; American Indians; rural health care; death; lifestyle; accident prevention; alcohol abuse; prediction; Wyoming; Montana
Abstract:
... Context: Many American Indian nations, tribes, and bands are at an elevated risk for premature death from unintentional injury. Previous research has documented a relationship between alcohol-related injury and subsequent injury death among predominately urban samples. The presence or nature of such a relationship has not been documented among American Indians living in the northern plains. Purpos ...
... Spinal cord injury (SCI) remains to be the most devastating type of trauma for patients because of long lasting disability and limited response to the acute drug administration and efforts at rehabilitation. With the purpose to identify potential targets for SCI treatment and to gain more insights into the mechanisms of SCI, the microarray data of GSE2270, including 119 raphe magnus (RM) samples a ...
... The aim of this study was to validate commercially available methods for porcine haptoglobin (Hp), C-reactive protein (CRP), serum amyloid A (SAA) and major acute phase protein (Pig-MAP) determinations. Intra and inter assay coefficients of variation (CVs) were lower than 20% in all cases with exception of inter assay CVs for CRP and Pig-MAP assays with samples of low acute phase proteins concentr ...
... Aspergillosis is a fungal disease caused by fungi of the genus Aspergillus, in particular A. fumigatus and A. flavus. This paper focuses on anatomopathological aspects resulting from a chronic infection from Aspergillus spp in the chicken (Gallus domesticus), in the herring gull (Larus cachinnans micaelli) and in the red-legged partridge (Alectoris rufa rufa). Microscopically, we observed some his ...
... A fractured frontal bone in an 8‐year‐old Arabian gelding was repaired surgically. The horse exhibited no detectable neurologic deficits before surgery. Anesthesia was induced with a combination of guaifenesin and sodium thiamylal and maintained on halothane in oxygen. Postoperatively, the neurologic status of the horse deteriorated, and it died. On postmortem examination, intracranial hemorrhage ...
... The objective of this study was to examine whether animal studies can reliably be used to determine the usefulness of methylprednisolone (MP) and other treatments for acute spinal cord injury (SCI) in humans. This was achieved by performing a systematic review of animal studies on the effects of MP administration on the functional outcome of acute SCI. Data were extracted from the published articl ...
... This review highlights some recent developments in our understanding of stress and physical injuries that occur before and during transport to slaughter, during handling at livestock markets, and at the time animals are put-up for slaughter within abattoirs. Stress in pigs during transfer to the stunning point within the abattoir has important effects on meat quality, and there is growing evidence ...
... BACKGROUND: Anterior chamber collapse syndrome has been recognised in various species and is associated with early‐life ocular disease or trauma. It is important to differentiate this acquired condition from a congenital malformation. CASE REPORT: An adult female koala (Phascolarctos cinereus) was referred for assessment of buphthalmos and severe keratitis of the right eye. The degree of keratitis ...
... Chronic skin wounds affect ≈3% of persons aged >60years (Davies et al., 2007) [1]. These wounds are typically difficult to heal by conventional therapies and in many cases they get infected making even harder the regeneration process. The antimicrobial peptide (AMP) LL37 combines antimicrobial with pro-regenerative properties and thus represents a promising topical therapy to address both problems ...
... This study evaluated the antioxidant activity of Cissampelos pareira (L.) Hirsuta (family: Menispermaceae). The roots of the C pareira (50% ethanol extract) were found to contain a large amount of polyphenols and exhibit significant and dose-dependent reducing ability, indicative of potent antioxidant ability both in vitro and in vivo. The C pareira extract (CPE) showed significant antioxidant act ...
... Herbal medicines are considered an intricate and integral part of humankind's knowledge systems. Time has proven their efficacy and safety for both human and animal applications. Modern science, guided by indigenous knowledge systems can further optimize the use of various herbal products. To widen the current focus on herbal medicines, a study was carried-out to determine antioxidant properties, ...
... Following spinal cord injury (SCI), the transmission of electrical signals is interrupted, and an oxidative microenvironment is generated, hindering nerve regeneration and functional recovery. The strategies of regulating oxidative pathological microenvironment while restoring endogenous electrical signal transmission hold promise for SCI treatment. However, challenges are still faced in simply fa ...
... In the present study, the pharmacological effects of oligosaccharides from Cistanche deserticola extract on inflammation, oxidative stress, and apoptosis in male albino rats with spinal cord injury were investigated. Lipid peroxidation, GSH, catalase, superoxide dismutase, acetylcholine esterase, GPx, ROS, and nitric acid were significantly altered in the rats with spinal cord injury. The mRNA exp ...
Iliya Shulman; Sergei Ogurcov; Alexander Kostennikov; Alexander Rogozin; Ekaterina Garanina; Galina Masgutova; Mikhail Sergeev; Albert Rizvanov; Yana Mukhamedshina
... Peripheral blood presents an available source of cells for both fundamental research and clinical use. In our study, we have evaluated the therapeutic potential of peripheral blood mononuclear cells (PBMCs) excluding the preliminary sorting or mobilization of peripheral blood stem cells. We have evaluated the regenerative potential of PBMCs embedded into a fibrin matrix (FM) in a model of pig spin ...
Witte, Stefan H.; Olaifa, Abayomi K.; Lewis, Andrew J.; Eggleston, Randy B.; Halper, Jaroslava; Kietzmann, Manfred; Baeumer, Wolfgang; Mueller, P.O. Eric
... Mesenchymal stem cells (MSCs) have recently made significant progress with multiple clinical trials targeting modulation of immune responses, regeneration of bone, cartilage, myocardia, and diseases like Metachromatic leukodystrophy and Hurler syndrome. On the other hand, the use of human embryonic and induced pluripotent stem cells (hPSCs) in clinical trials is rather limited mainly due to safety ...
... Ethnopharmacological relevance: Aqueous extracts from the bark of Mimosa tenuiflora (Willd.) Poirett (Mimosaceae), tradionally known as “tepescohuite”, are widely used for wound-healing and burns in middle and South America. No pharmacological data are available on the influence of aqueous extracts and high molecular constituents on human skin cells. Materials and methods: Tests were performed on ...
animal injuries; anthropogenic activities; beaches; children; decision making; ecosystems; fauna; flora; health insurance; human health; marine debris; risk; tourists; New Zealand
Abstract:
... The environmental, social and cultural importance of beaches permeates human society, yet the risk of human injury associated with increasing exposure to anthropogenic beach litter remains an unknown. While the impact of marine debris and beach litter on marine and coastal fauna and flora is a widely reported global issue, we investigate the impact on human health in New Zealand. Anthropogenic bea ...
One Health initiative; World Health Organization; animal health; animal injuries; animal welfare; data collection; demographic statistics; disease prevention; dogs; geographical distribution; health promotion; program evaluation; questionnaires; rabies; screening; vaccination; veterinary services; zoonoses; Africa; Asia
Abstract:
... The World Health Organization (WHO) and the World Organization for Animal Health (OIE) both recognize the importance of veterinary services in controlling zoonotic diseases, in preventing human injury, and in protecting the welfare of non-human animals. Furthermore, both organizations recommend regular evaluations of veterinary programs. Accordingly, we conducted a scoping review to collate the av ...
... Recovery after a spinal cord injury often requires that axons restore synaptic connectivity with denervated targets several centimeters from the site of injury. Here we report that systemic artemin (ARTN) treatment promotes the regeneration of sensory axons to the brainstem after brachial dorsal root crush in adult rats. ARTN not only stimulates robust regeneration of large, myelinated sensory axo ...
... OBJECTIVE: To report short and medium term outcomes, and complications, in dogs treated for rupture of the lateral glenohumeral ligament (LGHL) with a novel, arthroscopically assisted technique. STUDY DESIGN: Retrospective case series. ANIMALS: Dogs (n = 10) with LGHL injury. METHODS: Dogs were included after arthroscopic confirmation of rupture of the LGHL and treatment using an arthroscopically ...
animal injuries; cost effectiveness; home health services; hospitals; nutritional intervention; patients; speech; spinal cord; tube feeding; women
Abstract:
... This case was selected to illustrate the advantages of an interdisciplinary team approach when the aspiration risks of enteral tube feeding are examined for patients with multisystem involvement. The case reviews a 79-year-old widowed woman with a cervical 6 to 7 spinal cord injury requiring mechanical ventilation and enteral feeding. The patient had multiple complications that prolonged her hospi ...
... We investigated the relationship between damage from boat propeller scarring in seagrass (Thalassia testudinum) beds and the abundance of three faunal taxa commonly associated with seagrass vegetation in Charlotte Harbor and Tampa Bay, Florida. We chose sites with no damage (reference sites) to compare to those with propeller scarring within each of the two geographic locations. Thirty 141‐m² site ...
animal injuries; terrorism; working animals; cohort studies; long term effects; dogs; public safety; veterinary medicine; toxins; police; law enforcement; disasters; environmental exposure; disease surveillance; New York
Loxodonta africana; animal injuries; crop damage; death; human population; human-wildlife relations; landscapes; livestock; national parks; population density; rain; wildlife management; wildlife-livestock relations; Kenya
Abstract:
... People and wildlife have co-occurred, sharing resources for thousands of years, however, over the last four decades records of human–wildlife conflict have increasingly emerged. Human–elephant conflict is a form of such conflict, resulting from negative interactions between people and elephants. Human–elephant conflict affects local community livelihood and the success of elephant conservation. Ts ...
livestock and meat industry; disease diagnosis; disease detection; animal injuries; Salmonella; animal welfare; field experimentation; risk assessment; salmonellosis; training (people); animal transport; program evaluation; antemortem inspection; on-farm food safety; swine; Australia
Abstract:
... Objective A field trial was conducted to evaluate the effectiveness of on‐farm antemortem inspection performed by Australian pig producers in terms of proficiency in detecting unhealthy animals (suspects), the impact on food safety and animal welfare outcomes. Animals A total of 64 trial groups of market pigs (n = 10,703) were dispatched from 20 herds to three abattoirs in three states. Procedure ...
... Chemical composition and genotoxic properties of L. aegaeus (Griseb.) Boiss. which is a member of legumes and used as a cover crop, an antimicrobial agent for animal wounds and forage in Central Anatolia were detected for the first time. Nine secondary metabolites together with a new compound for nature were isolated from the n-butanol extract of Lotus aegaeus (Griseb.) Boiss aerial parts. The str ...
Enterococcus; Escherichia coli; Pseudomonas aeruginosa; Staphylococcus pseudintermedius; animal injuries; antibiotic resistance; antibiotics; bacteria; bacterial infections; bites and stings; cats; dog diseases; dogs; multiple drug resistance; therapeutics
Abstract:
... OBJECTIVE: To describe the bacterial bio‐burden of open‐treated wounds and make comparisons with bite wounds. DESIGN: Retrospective multicentre study. SAMPLE: Microbial culture between 2011 and 2013 from open‐treated wounds in dogs and cats (initiation of therapy n=88, follow‐up n=52) were compared to those from bite wounds (n=184). PROCEDURES: Bacteria were identified and tested for antibiotic su ...
Joe Fenn; Hongyu Ru; Nick D. Jeffery; Sarah Moore; Andrea Tipold; Franz J. Soebbeler; Adriano Wang‐Leandro; Christopher L. Mariani; Peter J. Early; Karen R. Muñana; Natasha J. Olby
anesthesia; animal injuries; body weight; cohort studies; dogs; intervertebral disks; pain; regression analysis; surgery; veterinary medicine
Abstract:
... BACKGROUND: Retrospective research recently identified a possible relationship between duration of surgery and outcome in severely affected dogs treated surgically for acute thoracolumbar intervertebral disk herniation (TL‐IVDH). HYPOTHESIS: That increased duration of surgery is associated with poorer outcome in dogs with absent pain perception treated surgically for TL‐IVDH. ANIMALS: Two hundred ...
obesity; body mass index; animal injuries; Chinese people; adults; Taiwan
Abstract:
... Background: The prevalence of obesity and injury has increased in Asian countries, but the relationship between obesity and injury is less well established. The aim of this study is to evaluate the relationship between body mass index (BMI), the occurrence of injury, and the injury-related expenditure among Taiwanese adults. Design: Retrospective cohort study. Methods: Our study sample consisted o ...
animal behavior; animal injuries; young animals; oviposition; laying hens; feather pecking; body weight; environmental factors; adults; laying performance; physiological response; egg production; distress; mortality; prediction; Rhode Island Red
Abstract:
... In laying hens, behavioral responses measured late in the laying period are associated with decreased performance. If measured early in the laying period, these behavioral responses could be used to predict performance later in life. The main objective of the present study was to investigate the association of the behavioral response toward a novel object at 23 wk of age with subsequent performanc ...
... Developmental Orthopaedic Disease (DOD) in limb joints of horses is frequent and is a common cause of pain and lameness. DOD is a multifactorial disease involving genetics, growth, feeding practices and exercise conditions leading to joint injuries. However, there is no clear understanding of the contribution of each factor. The aim of this cohort study was to assess the adjusted effects of breed ...
... BACKGROUND: Outcome of acute experimental spinal cord injury is strongly associated with tissue perfusion and oxygenation. Cardiopulmonary depression could affect outcome in dogs undergoing general anesthesia for surgical treatment of thoracolumbar intervertebral disk extrusion (IVDE). HYPOTHESIS/OBJECTIVES: To evaluate the effects of general anesthesia on functional outcome in dogs undergoing sur ...