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You searched for: Subject animal ovaries Remove constraint Subject: animal ovaries Subject cell lines Remove constraint Subject: cell lines Subject antineoplastic activity Remove constraint Subject: antineoplastic activity Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Carboplatin prodrug conjugated Fe₃O₄ nanoparticles for magnetically targeted drug delivery in ovarian cancer cells

Author:
Haiqin SongThe two authors contributed equally to this work.; Feifei Quan; Zhiqiang Yu; Minhua Zheng; Yan Ma; Haihua Xiao; Fang Ding
Source:
Journal of materials chemistry B 2019 v.7 no.3 pp. 433-442
ISSN:
2050-7518
Subject:
adverse effects; animal ovaries; antineoplastic activity; cell lines; chemistry; cisplatin; cytotoxicity; drug resistance; endocytosis; in vivo studies; iron oxides; magnetic fields; nanocarriers; nanoparticles; neoplasm cells; ovarian neoplasms; platinum; toxicity testing; zeta potential
Abstract:
... Platinum (Pt)-based drugs including cisplatin, carboplatin and oxaliplatin have been widely used as first-line anticancer regimens due to their excellent anticancer efficacy. However, the clinical application of these drugs is greatly limited due to their side effects and drug resistance. In this study, an antitumor drug delivery system based on carboplatin prodrug loading Fe₃O₄ nanoparticles (NPs ...
DOI:
10.1039/c8tb02574f

2. Taraxastane-type triterpenoids from the medicinal and edible plant Cirsium setosum

Author:
Peng-Cheng LIN; Lin-Lin JI; Xiang-Jian ZHONG; Jin-Jie LI; Xin WANG; Xiao-Ya SHANG; Sheng LIN
Source:
Chinese journal of natural medicines 2019 v.17 no.1 pp. 22-26
ISSN:
1875-5364
Subject:
Cirsium arvense; Oriental traditional medicine; animal ovaries; antineoplastic activity; cell lines; chemical structure; colorectal neoplasms; cytotoxicity; food plants; humans; inhibitory concentration 50; ovarian neoplasms; secretion; spectral analysis; triterpenoids; tumor necrosis factor-alpha
Abstract:
... Guided by TNF-α secretion inhibitory activity assay, four taraxastane-type triterpenoids, including two new ones, 22-oxo-20-taraxasten-3β, 30-diol (1) and 22α-hydroxy-20-taraxasten-30β, 30-triol (2), have been obtained from an active fraction of the petroleum ether-soluble extract of the the medicinal and edible plant Cirsium setosum. Their structures were elucidated by spectroscopic data and CD d ...
DOI:
10.1016/S1875-5364(19)30005-6

3. WITHDRAWN: 3,3′-Diindolylmethane suppresses ovarian cancer cell viability and metastasis and enhances chemotherapy sensitivity via STAT3 and Akt signaling in vitro and in vivo

Author:
Minghua Zou; Changhua Xu; Hua Li; Xianquan Zhang; Weidong Fan
Source:
Archives of biochemistry and biophysics 2018 pp. -
ISSN:
0003-9861
Subject:
animal ovaries; antineoplastic activity; caspase-3; cell lines; cell viability; cisplatin; drug therapy; gene expression; genes; hypoxia-inducible factor 1; metastasis; mice; neoplasm cells; ovarian neoplasms; phosphorylation; pro-apoptotic proteins; protein synthesis; signal transduction; vascular endothelial growth factors
Abstract:
... This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal ...
DOI:
10.1016/j.abb.2018.07.002

4. New halogenated constituents from Mangifera zeylanica Hook.f. and their potential anti-cancer effects in breast and ovarian cancer cells

Author:
Meran Keshawa Ediriweera; Kamani Hemamala Tennekoon; Achyut Adhikari; Sameera Ranganath Samarakoon; Ira Thabrew; E. Dilip de Silva
Source:
Journal of ethnopharmacology 2016 v.189 pp. 165-174
ISSN:
0378-8741
Subject:
2,2-diphenyl-1-picrylhydrazyl; Ayurvedic medicine; Mangifera; animal ovaries; antineoplastic activity; antineoplastic agents; apoptosis; bark; breast neoplasms; breasts; caspase-3; catechin; cell cycle; cell lines; chloroform; cytotoxicity; drug therapy; epithelial cells; epithelium; estrogen receptors; gene expression; growth factors; high performance liquid chromatography; histone deacetylase; mammary glands; mass spectrometry; neoplasm cells; nuclear magnetic resonance spectroscopy; ovarian neoplasms; pharmacokinetics; quantitative polymerase chain reaction; quercetin; receptor protein-tyrosine kinase; Sri Lanka
Abstract:
... Mangifera zeylanica Hook.f. (Anacardiaceae) is a plant endemic to Sri Lanka. Its bark has been used in traditional and Ayurvedic medicine for the treatment of various diseases including some cancers.This study was planned to isolate and identify potentially cytotoxic compounds from the bark of M. zeylanica, which may have contributed to its ethno pharmacological use in the treatment of cancer.The ...
DOI:
10.1016/j.jep.2016.05.047

5. A synthetic peptide inhibits human ovarian cancer cell motility

Author:
Yan Wei; Di Huang; Kaiqun Wang; Jingjing Du; Yinchun Hu
Source:
RSC advances 2015 v.5 no.102 pp. 83801-83808
ISSN:
2046-2069
Subject:
Western blotting; actin; animal ovaries; antineoplastic activity; cell lines; cell movement; cell viability; cytoskeleton; humans; mitochondria; neoplasm cells; ovarian neoplasms; peptide libraries; phages; phosphatidylinositol 3-kinase; pseudopodia; rough endoplasmic reticulum; signal transduction; staining; synthetic peptides; therapeutics; transmission electron microscopy
Abstract:
... Phage display libraries have been commonly used to identify recognition sites and antigen–antibody binding systems in tumor cells since the 1990s. In the previous study, we isolated a 12-mer binding peptide SVSVGMKPSPRP (SV-peptide) while isolating human ovarian cancer cells (SK-OV-3) using a random phage display library. Therefore, we tested the specific binding and anticancer properties of the S ...
DOI:
10.1039/c5ra08755d

6. Synthesis and Anticancer Evaluation of Some New 4-Amino-3- (p-methoxybenzyl)-4,5-dihydro-1,2,4-triazole-5-one Derivatives

Author:
Olcay Bekircan; Murat Kucuk; Bahittin Kahveci; Hakan Bektas
Source:
Zeitschrift für Naturforschung 2014 v.63 no.11 pp. 1305-1314
ISSN:
0932-0776
Subject:
aldehydes; animal ovaries; antineoplastic activity; breasts; cell lines; central nervous system; colon; condensation reactions; hydrazides; kidneys; leukemia; lungs; melanoma; organobromine compounds; prostate gland; sodium hydroxide; synthesis
Abstract:
... 4-Amino-3-p-methoxybenzyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl-acetic acid ethyl ester (2) was prepared from 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-one (1) and ethyl bromoacetate. Compound 3 was synthesized by the condensation of 2 with hydrazine hydrate. The treatment of compound 3 with various aromatic aldehydes resulted in the formation of arylidene hydrazides as cistrans conformers 4a - g. Th ...
DOI:
10.1515/znb-2008-1109

7. Platinum(ii) compounds bearing bone-targeting group: synthesis, crystal structure and antitumor activity

Author:
Zuqin Xue; Miaoxin Lin; Jianhui Zhu; Junfeng Zhang; Yizhi Li; Zijian Guo
Source:
Chemical communications 2010 v.46 no.8 pp. 1212-1214
ISSN:
1364-548X
Subject:
animal ovaries; antineoplastic activity; apoptosis; aqueous solutions; cell lines; chemical communication; chemical reactions; cisplatin; crystal structure; cytotoxicity; humans; moieties; osteosarcoma; ovarian neoplasms; phosphonates; platinum; solubility
Abstract:
... Platinum(ii) complexes bearing geminal bisphosphonate moieties have excellent solubility in both organic and aqueous solutions and show considerable cytotoxicity against human osteosarcoma (MG-63) and ovarian cancer (COC1) cell lines with different apoptotic pathways from that of cisplatin. ...
DOI:
10.1039/b922222g