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antagonists
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amino acids
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antibacterial properties
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- Author:
- Xiaoran Zhao; Yi Guo; Jiale He; Jianuo Liu; Shigen Ye
- Source:
- Aquaculture 2021 v.544 pp. 737056
- ISSN:
- 0044-8486
- Subject:
- Vibrio harveyi; amino acids; animals; antagonists; antibacterial properties; antitoxins; aquaculture; cell culture; cytotoxicity; flavonoids; genes; hemolysins; hemolysis; mutational analysis; pathogens; phospholipases; virulence
- Abstract:
- ... Vibrio harveyi hemolysin (VHH) is an important virulence determinant of V. harveyi. It is an extracellular protein with phospholipase activity and plays a key role in the process of pathogen infection of the host. The key role of VHH in the virulence of V. harveyi makes it an ideal target for the design of new antiviral drugs. We found that gastrodin is a natural flavonoid with no antibacterial ac ...
- DOI:
- 10.1016/j.aquaculture.2021.737056
- https://doi.org/10.1016/j.aquaculture.2021.737056
- Author:
- Zhi Zhou; Qiufeng Jiang; Mengqiang Wang; Feng Yue; Lingling Wang; Leilei Wang; Fengmei Li; Rui Liu; Linsheng Song
- Source:
- Fish & shellfish immunology 2013 v.35 no.3 pp. 825-832
- ISSN:
- 1050-4648
- Subject:
- Chlamys; Vibrio anguillarum; adrenergic receptors; agonists; amino acids; antagonists; antibacterial properties; bacteria; epinephrine; genes; hemocytes; hepatopancreas; homeostasis; immune response; immunocytes; isoprenaline; kidneys; messenger RNA; muscles; norepinephrine; octopamine; pathogens; phenylephrine; scallops; tissues; transcription (genetics); tyramine; vertebrates
- Abstract:
- ... The adrenergic receptors are a class of G protein-coupled receptors, through which norepinephrine and epinephrine trigger the second messenger to modulate the immune response in immunocytes of vertebrate. In the present study, a gene coding the homologue of α-adrenergic receptor was identified from scallop Chlamys farreri (designated CfαAR). Its deduced protein comprised 318 amino acids, and conta ...
- DOI:
- 10.1016/j.fsi.2013.06.020
- https://doi.org/10.1016/j.fsi.2013.06.020
- Author:
- Zhaoqun Liu; Zhi Zhou; Lingling Wang; Shuai Jiang; Weilin Wang; Ran Zhang; Linsheng Song
- Source:
- Developmental and comparative immunology 2015 v.49 no.2 pp. 217-224
- ISSN:
- 0145-305X
- Subject:
- Crassostrea gigas; G-protein coupled receptors; amino acids; antagonists; antibacterial properties; calcium; complementary DNA; cyclic AMP; gills; hemocytes; hepatopancreas; homeostasis; immune response; immunocytes; immunomodulation; kidneys; ligands; messenger RNA; muscles; narcotics; oysters; pathogens; second messengers
- Abstract:
- ... Opioid receptors (OR) are a group of G protein-coupled receptors with opioids as ligands, which play an important role in triggering the second messengers to modulate immune response in vertebrate immunocytes. In the present study, the full length cDNA of a homologue of δ-opioid receptor (DOR) for [Met5]-enkaphalin was cloned from oyster Crassostrea gigas (designated as CgDOR), which was 1104 bp e ...
- DOI:
- 10.1016/j.dci.2014.11.017
- https://doi.org/10.1016/j.dci.2014.11.017