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You searched for: Subject antineoplastic activity Remove constraint Subject: antineoplastic activity Subject term 2,5-dihydroxybenzoic acid Remove constraint Subject term: 2,5-dihydroxybenzoic acid
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1. Chemical profiling, in vitro biological activities and Pearson correlation between chemical profiling and anticancer activities of four Abies species from Turkey

Author:
Ayse Sahin Yaglioglu; Muhammet Samil Yaglioglu; Nahide Tosyalıoglu; Sevki Adem; Ibrahim Demirtas
Source:
South African journal of botany 2022 v. no. pp. -
ISSN:
0254-6299
Subject:
2,5-dihydroxybenzoic acid; Abies cilicica; Abies nordmanniana subsp. equi-trojani; Abies nordmanniana subsp. nordmanniana; Turkey (country); antineoplastic activity; catechin; chemical constituents of plants; drugs; oleic acid; palmitic acid; phytopharmaceuticals; principal component analysis; prostaglandin synthase; solvents; stearic acid; synergism
Abstract:
... Abies species are known to have various bioactive compounds and pharmacological activities. In the manuscript, their bioactive components and anticancer activities of four unexamined Abies in Anatolia (Abies cilicica subsp. isaurica, Abies nordmanniana subsp. nordmanniana, Abies nordmanniana subsp. bornmuelleriana, Abies nordmanniana subsp. equi-trojani) were investigated. The principal component ...
DOI:
10.1016/j.sajb.2022.08.005

2. Fermented curly kale as a new source of gentisic and salicylic acids with antitumor potential

Author:
Magdalena Michalak; Dominik Szwajgier; Roman Paduch; Wirginia Kukula-Koch; Adam Waśko; Magdalena Polak-Berecka
Source:
Journal of functional foods 2020 v.67 pp. 103866
ISSN:
1756-4646
Subject:
2,5-dihydroxybenzoic acid; Brassica oleracea var. sabellica; anti-inflammatory activity; antineoplastic activity; epithelial cells; fermentation; high performance liquid chromatography; human cell lines; lactic acid bacteria; mass spectrometry; neoplasms; polyphenols; salicylic acids; vegetables
Abstract:
... This paper demonstrates the role of curly kale fermentation by autochthonous lactic acid bacteria in the formation of bioactive derivatives of phenolic compounds which may have anticancer properties. LC-MS and HPLC analyses were performed and the content of polyphenols in curly kale before and during fermentation were determined. Bioactive properties of salicylic and gentisic acids were tested in ...
DOI:
10.1016/j.jff.2020.103866

3. Assessing Anticancer Potential of Blueberry Flavonoids, Quercetin, Kaempferol, and Gentisic Acid, Through Oxidative Stress and Apoptosis Parameters on HCT-116 Cells

Author:
Ebru Demirel Sezer; Latife Merve Oktay; Elif Karadadaş; Hikmet Memmedov; Nur Selvi Gunel; Eser Sözmen
Source:
Journal of medicinal food 2019 v.22 no.11 pp. 1118-1126
ISSN:
1557-7600
Subject:
2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
Abstract:
... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
DOI:
10.1089/jmf.2019.0098

4. Metabolic Profiling of Dietary Polyphenols and Methylxanthines in Normal and Malignant Mammary Tissues from Breast Cancer Patients

Author:
María Ángeles Ávila‐Gálvez; Rocío García‐Villalba; Francisco Martínez‐Díaz; Beatriz Ocaña‐Castillo; Tamara Monedero‐Saiz; Adela Torrecillas‐Sánchez; Beatriz Abellán; Antonio González‐Sarrías; Juan Carlos Espín
Source:
Molecular nutrition & food research 2019 v.63 no.9 pp. e1801239
ISSN:
1613-4125
Subject:
2,5-dihydroxybenzoic acid; animal tissues; antineoplastic activity; breast neoplasms; breasts; caffeine; chemoprevention; epithelial cells; grape seed extract; lemons; mammary glands; metabolites; metabolomics; methylxanthines; neoplasm cells; olives; patients; polyphenols; pomegranates; resveratrol; surgery; theobromine; urine
Abstract:
... SCOPE: Dietary polyphenols may protect against breast cancer. However, it is unknown whether polyphenols reach human malignant breast tumors in molecular forms and(or) at concentrations likely to act against cancer. METHODS AND RESULTS: Ninteen breast cancer patients consumed three capsules daily from biopsy‐confirmed diagnosis to surgery (6 ± 2 days). The capsules contained pomegranate, orange, l ...
DOI:
10.1002/mnfr.201801239

5. Composition and antioxidant, antibacterial, and anti-HepG2 cell activities of polyphenols from seed coat of Amygdalus pedunculata Pall

Author:
Cairui Lu; Cong Li; Bang Chen; Yehua Shen
Source:
Food chemistry 2018 v.265 pp. 111-119
ISSN:
0308-8146
Subject:
2,2-diphenyl-1-picrylhydrazyl; 2,5-dihydroxybenzoic acid; Aspergillus niger; Bacillus cereus; Bacillus subtilis; Escherichia coli; Prunus; Staphylococcus aureus; antibacterial properties; antineoplastic activity; antineoplastic agents; antioxidant activity; apigenin; apoptosis; ascorbic acid; cell proliferation; cell viability; cyanidin; free radicals; gallic acid; human cell lines; hydrogen peroxide; iron; kaempferol; keracyanin; naringenin; polyphenols; quercetin; quercitrin; seed coat; superoxide anion; viability assays
Abstract:
... This study aims at identifying the composition of polyphenols present in Amygdalus pedunculata Pall seed coat (APSC), and characterizing their antioxidant, antibacterial, and anticancer activities. The polyphenols from APSC were composed of 32 compounds. The compounds with important biological activities included apigenin 7-O-glucoside (the main component; 34.53 mg/100 g), quercitrin (23.43 mg/100 ...
DOI:
10.1016/j.foodchem.2018.05.091