An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
... The use of natural antioxidants is of increasing importance in the human diet, because they are recognised as compounds essential to health which minimize or delay the aging process. Despite apparent simplicity, however, it is very difficult to measure and quantify such properties, for which a robust analytical method is required. Because oxidation usually is caused by the presence of OH· radicals ...
... The present research aimed at evaluating the vitamin C, total phenolic content (TPC), phenolic compounds, carotenoids, and chlorophyll contents, as well as antioxidant activity (AAC) of six Actinidia species fruit. Vitamin C, phenolic compounds, carotenoids and chlorophylls were measured using high-performance liquid chromatography. TPC was determined using the Folin–Ciocalteau reagent, and AAC us ...
... In this study, the total phenolic amounts and antioxidant activities of plant extracts obtained from some common Mediterranean plant species collected from different places in Jordan were determined. The phenolic constituents of these extracts were also determined using HPLC. The total phenolic amounts ranged from 52.8 to 876.9 mg GAE per 100 g dry material. The antioxidant activities were evaluat ...
... The present investigation is focused on potential use of banana pseudostem (BPS), which otherwise is disposed off as a waste or incinerated, as a source of polyphenols or antioxidants. The total phenolics (TP) and total flavonoids (TF) in various solvent extracts of pseudostem (PS) of different banana cultivars varied from 7.58 to 291 mg gallic acid equivalent (GAE/g of extract) and from 4 to 80 m ...
... BACKGROUND: Chapati preparation involves various processing steps such as mixing the flour into dough, sheeting and baking. During these processing steps, flour components are likely to undergo changes in their nutrient and polyphenol composition and their antioxidant properties due to phenol‐mediated crosslinking of proteins and carbohydrates. Therefore, in the present study, changes in nutrition ...
... Black gram belongs to the Leguminosae family. It is one of the less studied legumes, although it is widely used in different parts of the world. Black gram in the form of cotyledon (dhal) is mainly used for the preparation of various food products. During milling of black gram into cotyledon, about 25% of the grain is removed as waste by-products. In the present study, nutrient content, phenolic a ...
... Gentisic acid and epicatechin are two major compounds in phenolic acids and flavonoids of litchi-flower-water extracts (LFWEs), respectively. Increased (p<0.05) serum lipids and liver size/lipid, damage/inflammatory indices, TBARS value, CRP level, MMP-9 activity, and decreased (p<0.05) liver GSH and TEAC levels, and SOD, CAT and GSH-Px activities were observed in high-fat-diet fed hamsters compar ...
... The genus Eryngium (family Apiaceae) consists of about 300 species. This genus is known to contain polyacetylenes, flavonoids and saponins, coumarins, and monoterpene glycosides. In folk medicine, various species are used for a wide range of foods; particularly roots are used against various inflammatory disorders, oedema, sinusitis, urinary infections, etc. The aim of the present study was to cha ...
... The aim of this study was to test contribution of plant-associated microorganism (PAMs) to metabolite stability/instability in a medicinal plant matrix.Therefore, PAM strains were isolated and identified based on relevant DNA sequences from Plantago lanceolata leaves. Sterile water extracts of P. lanceolata were incubated with the isolated strains and antioxidants (ascorbic acid (AA), and EDTA) fo ...
... The protective potential of litchi flower acetone extract (LFAE) against cadmium (Cd)- and lead (Pb)-induced hepatocytotoxicity, and transforming growth factor β1 (TGF-β1)-mediated activation of hepatic stellate cells (HSCs) were evaluated. Phenolic compounds were plentiful in LFAE (429mg/g of dried extract); epicatechin (122.1mg/g of dried extract), gentisic acid (60.2mg/g of dried extract) and p ...
... Methanol extract subfractions of the edible white jelly mushroom (Tremella fuciformis), were assessed for the following antioxidant properties: ABTS⁺ radical scavenging activity, 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical scavenging activity, and inhibitory activity of human low‐density lipoprotein (LDL) oxidation. Among the subfractions tested, the chloroform subfraction exhibited the strongest ...
... This study was conducted to evaluate, the phytochemical composition of leaves and roots of five Tunisian populations of castor (Ricinus communis L.). Levels of total phenolic contents, total flavonoids, and condensed tannins of methanolic extracts were determined by UV-spectrophotometer. Phenolic compounds were identified and quantified by RP-HPLC (reverse phase HPLC). Gentisic acid, catechin, rut ...
... The aim of this research was to determine the total phenolic and flavonoid contents as well as to measure antioxidant activity of 24 different commercial beers consumed in Serbia. The major phenolic acids (gallic acid, protocatechuic acid, 4-hydroxybenzoic acid, 2,5-dihydroxybenzoic acid, vanillic acid, caffeic acid, syringic acid, p-coumaric acid, ferulic acid, sinapic acid, salicylic), (+)-catec ...
... Phenolic contents and antioxidant capacities from different solvent extracts (petroleum ether, ethyl acetate, methanol, butanol and water) of Aster scaber leaf were investigated. Antioxidant activity was evaluated by three different methods, namely DPPH radical scavenging activity, reducing power assay and phosphomolybdenum activity. A total of twenty-three polyphenolic compounds were ident ...
... In this present study, we probed the use of banana rhizome (BR), which is a bio-waste of banana plant as a source of polyphenols or antioxidants. Among the rhizome of eight commercial banana cultivars grown in India, cv. Nanjanagudu Rasabale (NR) displayed highest Total Phenolic Content (TPC), Total Flavonoid Content (TFC) and DPPH radical scavenging activity. Hence, cv. NR is used to study phenol ...
... Phenolic contents, antioxidant and antimicrobial activities were determined by two samples from summer (June) and winter (December) seasons of Ligularia fischeri var. spiciformis Nakai. A total of 24 phenolic compounds were identified by ultra-performance liquid chromatography (UPLC) analysis. Myricetin (1964.35 and 1829.12 μg/g) was the most dominant flavonol compared to quercetin and kaempferol. ...
... This work reports the in vitro inhibitory activity of water decoctions of leaves, germ flour, pulp, locust bean gum and stem bark of carob tree on α-amylase, α-glucosidase, acetylcholinesterase and butyrylcholinesterase. The antioxidant activity and the chemical characterisation of the extracts made by spectrophotometric assays and by high-performance liquid chromatography are also reported. Leave ...
Vasiliki Kachrimanidou; Nikolaos Kopsahelis; Maria Alexandri; Androniki Strati; Chryssavgi Gardeli; Seraphim Papanikolaou; Michael Komaitis; Ioannis K. Kookos; Apostolis A. Koutinas
2,2-diphenyl-1-picrylhydrazyl; 2,5-dihydroxybenzoic acid; 3-hydroxybutyric acid; acid deposition; alkali treatment; antioxidant activity; antioxidants; biodiesel; bioreactors; biorefining; chemical precipitation; chlorogenic acid; coproducts; dietary supplements; fermentation; glycerol; high performance liquid chromatography; hydrolysates; hydrolysis; industrial byproducts; isoelectric point; protein concentrates; protein isolates; streams; sunflower meal; value added
Abstract:
... Sunflower meal (SFM) has been used for the production of an antioxidant-rich fraction, protein isolate and nutrient-rich fermentation supplements. Suspension of SFM in water led to the production of a lignocellulose-rich fraction and a protein concentrate fraction. The ethanolic extract from the SFM showed high antioxidant activity, as it was measured by the DPPH (1,1-diphenyl-2-picrylhydrazyl rad ...
... The objectives of this study were to evaluate the potential of custard apple (Annona squamosa L.) in the production of a beverage fermented using Saccharomyces cerevisiae (NCIM 3282) yeast and assess the antioxidant capacity, total phenolic content and DNA damage‐protecting activity of custard apple fruit wine (CAFW). The antiradical activities of CAFW were measured using DPPH, FRAP and DMPD scave ...
... This work reports the in vitro antioxidant and inhibitory activities of hexane, methanol and water extracts of cork oak (Quercus suber) against acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), α-amylase and α-glucosidase. The total content of phenolics (TPC), tannins (TTC) and flavonoids (TFC), and the HPLC profile of the main phenolic compounds present in the extracts, were also determ ...
... The present study investigates the phenolic profile of exudates and extracts of the green algae Dunaliella tertiolecta, harvested in natural seawater in the absence (control) and in the presence of Cu(II) (315 and 790 nmol L⁻¹) and Fe(III) (900 nmol L⁻¹) in order to identify and quantify the phenolic compounds produced under metallic stress conditions. The presence of metal ions modifies the growt ...
... Research efforts on the production of chitosan nanoparticles (NP) as delivery systems of bioactive compounds such as polyphenols have been made along the last decade. Nevertheless, the effect of the phenolic compound structure in the production of these NP was never evaluated so far. Low and high molecular weights chitosan (LMWC and HMWC) NP loaded with the phenolic acids, protocatechuic (PA) and ...
... The study of phenolic compounds profiles and antioxidative activity in ginseng fruit, leaves, and roots with respect to cultivation years, and has been little reported to date. Hence, this study examined the phenolic compounds profiles and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free-radical-scavenging activities in the fruit, leaves, and roots of Korean ginseng (Panax ginseng Meyer) as a function o ...
... The antioxidant capacities of three derivatives of hydroxybenzoic acids (Gentisic acid, protochatechuic acid and vanillic acid) in sardine oil were compared. Peroxide value, conjugated diene value, p-anisidine value and thiobarbituric acid reactive substances (TBARS) value were assessed to determine the oxidative stability provided by these substances to the sardine oil. Results showed that gentis ...
... Several studies have demonstrated the antioxidant capacity of seaweeds, which can be used for the development of biopharmaceuticals with extensive medical application. Antioxidant therapies appear to attenuate the organic deterioration originated by an excessive oxidative stress, which could prevent the harmful effects of various injuries such as ischemia-reperfusion (I/R) among others. Marine bro ...
... The aim of the study was to investigate the antioxidant properties, phenolic and flavonoid contents and composition and content of ascorbic acid in Pleurotus ostreatus and Pleurotus eryngii enriched simultaneously with selenium (Se) and zinc (Zn). Non-enriched mushrooms contained Se and Zn at the level as in the most popular mushrooms. The total phenolic content (TPC) for non-enriched P. ostreatus ...
... Many compounds in mushrooms are biologically active; however, the in vivo actions of their metabolites are poorly understood. An in vitro system, GIS1, was used to simulate the fermentation action of microbiota in each colon region. We used MycoPo, a natural product obtained from the lyophilized mycelia of different Pleurotus ostreatus species to determine the biological effects in human-colon reg ...
... This study characterized the phenolic profile in siriguela, umbu-cajá and mangaba, as well in their frozen pulps (FPs). The bioaccessibility of phenolic compounds and the antioxidant activity of the FP dialysates were determined following exposure to simulated gastrointestinal conditions. The profile of phenolic compounds identified in fruit and FPs were relatively similar. After pulp processing, ...
Sara Savini; Monica Rosa Loizzo; Rosa Tundis; Massimo Mozzon; Roberta Foligni; Edoardo Longo; Ksenia Morozova; Matteo Scampicchio; Daniel Martin-Vertedor; Emanuele Boselli
... The antioxidant properties of fresh black truffles (Tuber melanosporum) (T.) refrigerated at 4 °C under different packaging conditions: air atmosphere (A), reduced pressure (V), mix 1% O₂/99% N₂ (ON) and mix 40% CO₂/60% N₂ (CN) were evaluated during 28 days of storage. The results were compared with the volatile fingerprint determined by SPME-GC/MS and with the phenolic antioxidants characterized ...
... Five kinds of hydroxybenzoic acids including gallic acid (GLA), gentisic acid (GTA), protocatechuic acid (PA), syringic acid (SA) and vanillic acid (VA) were grafted onto chitosan (CS) through carbodiimide mediated coupling reaction. The obtained CS derivatives were further developed into films by casting. The physical, mechanical and antioxidant properties of hydroxybenzoic acid-g-CS films were c ...
... Acer truncatum seed coat is generally abandoned as waste during the process of manufacturing seed oil due to a lack of knowledge of the phytochemical composition of this byproduct. It is well known that brown-colored seed coat is rich in polyphenols; therefore, we investigated the bioactive phenolic composition of A. truncatum seed coat in this study. To obtain an extract containing most bioactive ...
... Total phenolic content (TPC), individual phenolic acid and antioxidant capacity of whole grain and bran fraction 18 rices with different bran color were investigated. The levels of TPC in bound fractions were significantly higher than those in the free fractions either in the whole grains or brans. The main bound phenolic acids in white rice samples were ferulic acid, p-coumaric acid, and isoferul ...
... Soluble carbohydrates, volatile and phenolic compounds from calabura fruit as well as its antioxidant activity were assessed. The low amount of fermentable oligo-, di-, and monosaccharides and polyols (FODMAPs) and similar amount of glucose and fructose allow us to classify the calabura berry as low-FODMAPs. The terpenes β-Farnesene and dendrolasin identified by SPME-GC-MS were the major volatile ...
... This study aims at identifying the composition of polyphenols present in Amygdalus pedunculata Pall seed coat (APSC), and characterizing their antioxidant, antibacterial, and anticancer activities. The polyphenols from APSC were composed of 32 compounds. The compounds with important biological activities included apigenin 7-O-glucoside (the main component; 34.53 mg/100 g), quercitrin (23.43 mg/100 ...
... The aim of this study was to identify and quantify the phenolic compounds of the Ethyl acetate extract from Lepidium draba using HPLC-TOF/MS; and to investigate the antioxidant potencies. In this work, we have found that the Ethyl acetate soluble fraction of L. draba is a good source of antioxidant, which is the result of its phenolic acids and flavonoids. Five methods were conducted, to determine ...
2,5-dihydroxybenzoic acid; antioxidant activity; chickpeas; emulsions; gel chromatography; germination; in vitro studies; mass spectrometry; molecular weight; protocatechuic acid; refractive index
Abstract:
... Our recent study found that antioxidative activity of phenolic compounds extracted from germinated chickpea was boosted in both in vitro assays and oil-in-water emulsions [Xu et al. Food Chem.2018, 250, 140]. The purpose of this study was to elucidate the mechanism by which germination enhances the antioxidative activity of the phenolic compounds extracted from chickpea. Liquid chromatography coup ...
... The extracts of Moringa oleifera, a traditional medicinal and culinary plant containing phytochemicals with diverse therapeutic properties were investigated. Five parts of the plant were extracted with 5 different solvents to analyze the total phenolics content (TPC) and total flavonoids content (TFC) which were then tested for their antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH) ...
2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
Abstract:
... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
2,2-diphenyl-1-picrylhydrazyl; 2,5-dihydroxybenzoic acid; Fourier transform infrared spectroscopy; absorption; amino acids; antioxidant activity; antioxidants; beta-lactoglobulin; biocompatibility; biopolymers; chemical bonding; circular dichroism spectroscopy; electron paramagnetic resonance spectroscopy; free radicals; mass spectrometry; monitoring; protein secondary structure; ultraviolet radiation
Abstract:
... Dietary phenolic compounds display strong antioxidant capabilities but face limited practical applications as a result of their poor biocompatibility (high immune resistance). Some food proteins possess mild antioxidant capabilities but are often not sufficient to maintain a reactive oxidative species balance. In this study, we overcome these barriers by covalently conjugating a natural phenolic a ...
... Millet grains are small seeded Kharif crop used as food and feed. Due to presence of bioactive compounds and important minerals, millets have their own importance among cereal grains. Finger millet is a mixture of gallic acid; p-hydroxybenzoic acid; gentisic acid; caffeic acid; syringic acid; p-coumaric acid; sinapic acid; salicylic acid; trans-cinnamic acid. Foxtail millet contains gallic acid; p ...
... Cowpea is a well-known nutrition rich African leafy vegetable that has potential to sustain food and nutrition insecurity in sub-Saharan Africa. Consumption of cowpea legumes is associated with reduced risk of type 2 diabetes mellitus. Therefore, the present study was designed to evaluate the (i) variation in phenolic metabolites in seven cowpea cultivars (VOP1, VOP2, VOP3, VOP4, VOP5, VOP7, and V ...
... The present study aimed to characterize the nutritional value and potential use of elderberries as a source of antioxidant compounds. The chemical composition, fatty acids and phenolic compounds were determined for elderberries. The optimization of extraction parameters was designed with a Box-Behnken design coupled with response surface methodology (RSM) and desirability function analysis. The pr ...
... Medicinal Ganoderma mushrooms have long tradition in Asia, and recently they began to be consumed in Europe as well. Among hundreds of Ganoderma species, only a few of them are intensively investigated, i.e., G. lucidum and G. applanatum, whereas the chemistry and bioactivities of the other species, especially of European origin, still remain unknown. This study comprises detailed chemical analysi ...
C. Cardoso; H. Pereira; J. Franca; J. Matos; I. Monteiro; P. Pousão-Ferreira; A. Gomes; L. Barreira; J. Varela; N. Neng; J. M. Nogueira; C. Afonso; N. M. Bandarra
... Recently isolated microalgae Tetraselmis sp. IMP3, Tetraselmis sp. CTP4, and Skeletonema sp. were studied. The three novel strains contained relatively high levels of polyunsaturated fatty acids (PUFA) and n3 PUFA. However, highly unsaturated n3 FA contents were relatively low (5.7–13.0% of the total FA). In general, eicosapentaenoic acid (EPA, 20:5 n3) contents were low (< 6.4% of the total FA). ...
... The first step in introducing a medicinal plant into farming systems and industrial pharmacology is the realization of its metabolic profile and biological features. In the present study, ten Verbascum species including V. cheirantifolium, V. erianthum, V. macrocarpum, V. punalense, V. sinuatum, V. songaricum, V. speciosum, V. stachidiforme, V. thapsus, and V. densiflorum were collected from Iran ...
... BACKGROUND: Red amaranth (Amaranthus gangeticus L.) has great diversity in Bangladesh, India, and South East Asia with multipurpose uses. The bright red-violet colored A. gangeticus is a popular and low-cost leafy vegetable in the Asian continent including Bangladesh and India because of attractive leaf color, taste, adequate nutraceuticals, phenolic compounds, and sole source of betalains. The na ...
... Beneficial therapeutic effects of phenolic acids have been proven in various research projects including in vivo and in vitro studies. Gentisic acid (GA) is a phenolic acid that has been associated with useful effects on human health, such as antiinflammatory, antigenotoxic, hepatoprotective, neuroprotective, antimicrobial, and especially antioxidant activities. It is an important metabolite of as ...
... The chemical ingredients of pine and thyme honey were studied, along with their medicinal activity properties. A method was validated for common honey compounds using LC-TOF/MS to analyze the ingredients. In vitro antiproliferative, antioxidant, anticholinesterase, anti-inflammatory, tyrosinase inhibitory, and urease inhibitory activities were used to investigate the therapeutic potentials. The an ...
... Jatropha species have been shown to be an important source of secondary metabolites with different biological effects. Jatropha cinerea (Ortega) Müll. Arg and Jatropha cordata (Ortega) Müll. Arg are distributed in the Northwestern region of Mexico, are adapted to extreme weather conditions and are widely used (stems, leaves, and sap) in traditional medicine. The aim of the present study was to car ...
... Quorum sensing controls bacterial virulence through signaling molecules, which plays a vital role in managing foodborne pathogens that cause food spoilage and human infections. Though many synthetic compounds have been used to control infection, antibiotic resistance has become a global issue. Targeting the bacterial quorum sensing using the bioactive compounds could be an alternative strategy to ...