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You searched for: Subject antioxidant activity Remove constraint Subject: antioxidant activity Subject term antineoplastic activity Remove constraint Subject term: antineoplastic activity
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1. Antioxidant and Anticancer Effects of Epsilon-Poly-L-lysine Produced by Two Novel Strains of Paenibacillus polymyxa HS6 and Stenotrophomonas maltophilia YS8

Author:
Hamidreza Hagh Ranjbar; Afrouzossadat Hosseini Abari; Seyed Mahdi Ghasemi; Najmeh Ghorbani
Source:
Biotechnology and bioprocess engineering 2022 v.27 no.4 pp. 586-595
ISSN:
1226-8372
Subject:
Fourier transform infrared spectroscopy; Paenibacillus polymyxa; Stenotrophomonas maltophilia; antineoplastic activity; antioxidant activity; antioxidants; bioactive compounds; bioprocessing; biotechnology; chemical precipitation; cytotoxicity; flow cytometry; high performance liquid chromatography; nucleotide sequences; polyacrylamide gel electrophoresis; polypeptides; sequence analysis; sodium; soil; thiazolyl blue
Abstract:
... Epsilon-Poly-L-lysine (ε-PL) is a non-toxic cationic homopolypeptide with unique bioactive properties. In this study, two novel polylysine producers, Paenibacillus polymyxa HS6 and Stenotrophomonas maltophilia YS8 were isolated from different soil samples and identified by 16S rDNA sequence analysis. To obtain pure cationic polypeptide from these bacteria, chemical precipitation with sodium tetrap ...
DOI:
10.1007/s12257-022-0065-1

2. Antioxidant and anticancer activities of Annona muricata L. and Antidesma bunius L. leaves, and molecular networking analysis using LC-MS/MS metabolomics

Author:
Aya Gabriella Peña; Michael Russelle Alvarez; Kimberly Delica; Patrick Gabriel Moreno; Rowell Abogado; Sheryl Joyce Grijaldo; Edcyl Lee Salac; Froila Marie Deniega; Manolo Basingan; Cherry Mae Ravidas; Francisco Heralde; Gladys Cherisse Completo; Isagani Padolina; Ruel Nacario
Source:
South African journal of botany 2022 pp. -
ISSN:
0254-6299
Subject:
Annona muricata; Antidesma bunius; Philippines; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; chlorophyll; ethyl acetate; growth retardation; hexane; humans; indoles; leaves; lung neoplasms; metabolomics; methanol; phytochemicals; toxicity testing
Abstract:
... Several natural products are known to have anticancer activity, which helps prevent cancer. This study explores the potential use of different extracts of Annona muricata L. and Antidesma bunius L. leaves as an anticancer drug by testing its anti-oxidative and anticancer properties. Furthermore, metabolomics of these plant extracts was performed to characterize them. This project studied the bioac ...
DOI:
10.1016/j.sajb.2022.06.019

3. Aqueous two-phase extraction of polysaccharides from Selaginella doederleinii and their bioactivity study

Author:
Gang Li; Xiankui Ma; Yongmei Jiang; Weiwei Li; Yongling Wang; Li Liu; Chengxin Sun; Shiji Xiao; Jie Lan; Juxiang Kuang; Gang Wang
Source:
Process biochemistry 2022 v.118 pp. 274-282
ISSN:
1359-5113
Subject:
Selaginella doederleinii; antineoplastic activity; antioxidant activity; antioxidants; ethanol; liquids; polysaccharides; salt concentration; thermogravimetry; ultrasonics
Abstract:
... In this study, the ethanol/salt aqueous two-phase system was firstly used to extract Selaginella doederleinii polysaccharides (SDP). Through single factor and response surface analysis, the best extraction conditions were as follows: extraction time of 40 min, ultrasonic power of 280 W, ethanol concentration of 35%, inorganic salt concentration of 0.22 g/mL, and liquid/solid ratio of 25 mL/g with ...
DOI:
10.1016/j.procbio.2022.04.024

4. Assessment of antioxidant, antimicrobial, and anticancer activities of Sisymbrium officinale plant extract

Author:
Mahmoud Khalid; Mousa Amayreh; Saadi Sanduka; Zaidoun Salah; Fuad Al-Rimawi; Ghassab M. Al-Mazaideh; Abdulkareem A. Alanezi; Fadel Wedian; Fawaz Alasmari; Mohammed Helmy Faris Shalayel
Source:
Heliyon 2022 v.8 no.9 pp. e10477
ISSN:
2405-8440
Subject:
Escherichia coli; Gram-negative bacteria; Sisymbrium officinale; Staphylococcus; Streptococcus; air drying; antimicrobial properties; antineoplastic activity; antioxidant activity; antioxidants; breast neoplasms; breasts; cell lines; colon; ethanol; flavonoids; markets; neoplasm cells; plant extracts; ultrasonic treatment
Abstract:
... The most efficient and safe source of medications is the natural and traditional medications which are produced from plants and herbs. In this study, Sisymbrium officinale (S. officinale) was tested to explore its total phenolic and flavonoids contents. Antioxidant, antimicrobial, and anticancer activities were assessed as well. S. officinale was bought from a local Palestinian market, air-dried, ...
DOI:
10.1016/j.heliyon.2022.e10477

5. Bioactive Compounds, Antioxidant, Anti-Inflammatory, Anti-Cancer, and Toxicity Assessment of Tribulus terrestris—In Vitro and In Vivo Studies

Author:
Malik Waseem Abbas; Mazhar Hussain; Saeed Akhtar; Tariq Ismail; Muhammad Qamar; Zahid Shafiq; Tuba Esatbeyoglu
Source:
Antioxidants 2022 v.11 no.6 pp. -
ISSN:
2076-3921
Subject:
Tribulus terrestris; antineoplastic activity; antioxidant activity; blood serum; body weight; breast neoplasms; denaturation; drugs; edema; egg albumen; hemolysis; histopathology; metabolites; methanol; mice; myricetin; neoplasm cells; rutin; serum albumin; toxicity
Abstract:
... Tribulus terrestris L. belongs to the family Zygophyllaceae and integral part of various ancient medicinal systems including Chinese, Indian, and European to combat various health ailments. The aim of the present study was to assess the phytochemical constituents, in vitro antioxidant activity using DPPH, FRAP, and H₂O₂ assays, in vitro anticancer activity using MTT assay, and in vitro and in vivo ...
DOI:
10.3390/antiox11061160

6. Biochemical and mitochondrial membrane potential changes relating to betulinic acid-mediated anticancer activity in murine ascites Dalton's lymphoma

Author:
Anamika Bhaumik; Atanu Bhattacharjee; Surya Bali Prasad
Source:
Phytomedicine plus 2022 v.2 no.1 pp. 100211
ISSN:
2667-0313
Subject:
antineoplastic activity; antioxidant activity; ascites; betulinic acid; computer simulation; glutathione; longevity; lymphoma; membrane potential; mice; mitochondrial membrane; succinate dehydrogenase (quinone)
Abstract:
... Betulinic acid, a naturally occurring pentacyclic triterpenoid is found in a variety of plants. A range of biological properties including anticancer activity has been reported for betulinic acid. Changes in glutathione and some glutathione-related enzymes and mitochondrial membrane potential have not been explored relating to the anticancer activity of betulinic acid against murine ascites Dalton ...
DOI:
10.1016/j.phyplu.2021.100211

7. Blue is not enough: biological activities of C‐phycocyanin extracts from Anabaena cylindrica

Author:
Inês PE Macário; Telma Veloso; Andreia PM Fernandes; Margarida Martins; Tânia R Dias; Helena Oliveira; Fernando JM Gonçalves; Sónia PM Ventura; Joana L Pereira
Source:
Journal of chemical technology and biotechnology 2022 v.97 no.5 pp. 1171-1179
ISSN:
0268-2575
Subject:
Anabaena cylindrica; Spirulina; antineoplastic activity; antioxidant activity; antioxidants; biocompatibility; biomass; biotechnology; dyes; feedstocks; freeze drying; phycocyanin
Abstract:
... BACKGROUND: Natural products are currently in the spotlight due to the increasing awareness of consumers. Among these products is phycocyanin (C‐PC), a blue colorant that can be extracted from cyanobacteria – a poorly explored feedstock – and applied in several fields, due to its argued health benefits. Arthropira (previously called Spirulina) is the major source of C‐PC nowadays, but within the s ...
DOI:
10.1002/jctb.7001

8. Chemical Composition of Reichardia tingitana Methanolic Extract and Its Potential Antioxidant, Antimicrobial, Cytotoxic and Larvicidal Activity

Author:
Salama A. Salama; Zarraq E. Al-Faifi; Yasser A. El-Amier
Source:
Plants 2022 v.11 no.15 pp. -
ISSN:
2223-7747
Subject:
Aedes aegypti; Bacillus cereus; Clostridium tetani; Reichardia; Salmonella Typhimurium; Staphylococcus xylosus; antineoplastic activity; antioxidant activity; antioxidants; chemical composition; cytotoxicity; larvicides; methanol; neoplasms; oleic acid; terpenoids
Abstract:
... The biggest challenges are locating effective, reasonably priced, and eco-friendly compounds to treat diseases caused by insects and microbes. The aim of this study was to employ GC-MS to assess the biological potency and chemical composition of the aerial parts of Reichardia tingitana (L.) Roth. Using this technique, 17 components were interpreted from the extracted plant, accounting for around 1 ...
DOI:
10.3390/plants11152028

9. Chemical Profiling and Evaluation of Antioxidant and Anticancer Potential of Tuber Crop Amorphophallus commutatus var. wayanadensis

Author:
Sreena Raj; Rama Jayaraj; Gothandam Kodiveri Muthukaliannan
Source:
Plant foods for human nutrition 2022 v.77 no.1 pp. 68-76
ISSN:
0921-9668
Subject:
Amorphophallus; DNA fragmentation; antineoplastic activity; antioxidant activity; apoptosis; ascites; carcinoma; caspase-3; cell cycle checkpoints; cytotoxicity; dietary supplements; fractionation; functional foods; health services; hematologic tests; herbaceous plants; human cell lines; human nutrition; longevity; therapeutics; toxicity testing; India
Abstract:
... Cancer and cancer-related diseases are a global health concern in the present scenario. Functional food and nutraceuticals are considered as a boon towards cancer management. Amorphophallus commutatus var. wayanadensis (ACW) is an herbaceous plant used by the local communities of Wayanad, India, for food and primary healthcare. Various radical scavenging and reducing power assays were undertaken t ...
DOI:
10.1007/s11130-021-00942-3

10. Comparative Evaluation of the Potential Antitumor of Helleborus purpurascens in Skin and Breast Cancer

Author:
Ciprian Nicolae Pilut; Aniko Manea; Ioana Macasoi; Amadeus Dobrescu; Doina Georgescu; Roxana Buzatu; Alin Faur; Stefania Dinu; Doina Chioran; Iulia Pinzaru; Monica Hancianu; Cristina Dehelean; Daniel Malița
Source:
Plants 2022 v.11 no.2 pp. -
ISSN:
2223-7747
Subject:
Helleborus; antineoplastic activity; antioxidant activity; apoptosis; ascorbic acid; breast neoplasms; cancer therapy; cell lines; cytotoxicity; epicatechin; kaempferol; neoplasm cells; quercetin
Abstract:
... In the field of oncology, the plant kingdom has an inexhaustible supply of bioactive compounds. Phytochemical compounds isolated from Helleborus species have been found to be useful in various chronic diseases. This has brought Helleborus to the attention of medical researchers. H. purpurascens is a plant characteristic of the Carpathian area, known since ancient times for its beneficial effects. ...
DOI:
10.3390/plants11020194

11. Cytotoxic effect of plant extract-based nanoparticles on cancerous cells: a review

Author:
Jyotika Grewal; Vijay Kumar; Hemant Rawat; Yashika Gandhi; Ravindra Singh; Arjun Singh; Gajji Babu; Narayanam Srikanth; Sujeet K. Mishra
Source:
Environmental chemistry letters 2022 v.20 no.4 pp. 2487-2507
ISSN:
1610-3653
Subject:
antineoplastic activity; antioxidant activity; apoptosis; autophagy; cell cycle checkpoints; cytotoxicity; drug delivery systems; environmental science; medicinal plants; reactive oxygen species
Abstract:
... Cancer is one of the most fatal diseases causing deaths of millions of people worldwide. Since actual cancer treatments are rarely efficient and often toxic, there is a demand for innocuous and more effective anticancer drugs. For instance, metal/metal oxide nanoparticles allow controlled drug release and drug delivery to specific targets. In particular, medicinal plant-based metal nanoparticles a ...
DOI:
10.1007/s10311-022-01422-z

12. Ecofriendly Synthesis of Biosynthesized Copper Nanoparticles with Starch-Based Nanocomposite: Antimicrobial, Antioxidant, and Anticancer Activities

Author:
Mohamed Hasanin; Mohamed A. Al Abboud; Mohamed M. Alawlaqi; Tarek M. Abdelghany; Amr H. Hashem
Source:
Biological trace element research 2022 v.200 no.5 pp. 2099-2112
ISSN:
0163-4984
Subject:
Aspergillus niger; Bacillus subtilis; Candida albicans; Escherichia coli; Fourier transform infrared spectroscopy; X-ray diffraction; antifungal properties; antineoplastic activity; antioxidant activity; antioxidants; ascorbic acid; biosynthesis; cell lines; copper nanoparticles; energy-dispersive X-ray analysis; nanocomposites; research; starch; trace elements; transmission electron microscopes; ultraviolet-visible spectroscopy
Abstract:
... In recent years, polysaccharides-based nanocomposites have been used for biomedical applications. In the current study, a nanocomposite based on myco-synthesized copper nanoparticles (CuNPs) and starch was prepared. The prepared nanocomposite was fully characterized using UV–visible spectroscopy (UV–vis), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron mi ...
DOI:
10.1007/s12011-021-02812-0

13. Effects of sulfation and carboxymethylation on Cyclocarya paliurus polysaccharides: Physicochemical properties, antitumor activities and protection against cellular oxidative stress

Author:
Liuming Xie; Zhibing Huang; Li Qin; Qiang Yu; Yi Chen; Haibing Zhu; Jianhua Xie
Source:
International journal of biological macromolecules 2022 v.204 pp. 103-115
ISSN:
0141-8130
Subject:
Cyclocarya paliurus; antineoplastic activity; antioxidant activity; apoptosis; cell cycle checkpoints; cell viability; glucose; interphase; lactate dehydrogenase; malondialdehyde; neoplasms; oxidative stress; phagocytosis; polysaccharides; secretion; superoxide dismutase
Abstract:
... The Cyclocarya paliurus polysaccharide (CP) was chemically modified to produce sulfated derivatives (S-CP) and carboxymethylated derivatives (CM-CP). Subsequently, the antioxidant activity, cytoprotective effect and antitumor activity of these derivatives were investigated to establish the relationship between their structure and functional activity. The results found that chemical modifications r ...
DOI:
10.1016/j.ijbiomac.2022.01.192

14. Evaluation of a novel phosphorylated corn straw xylan for enhancement of thermal stability, crystallinity and functional activity

Author:
Shiquan Qian; Yuting Yu; Jing Ma; Enjie Diao; Shijia Ye; Jiamin Gao; Ying Liu; Weicheng Hu
Source:
International journal of food science & technology 2022 v.57 no.1 pp. 481-488
ISSN:
0950-5423
Subject:
2,2-diphenyl-1-picrylhydrazyl; antineoplastic activity; antioxidant activity; corn straw; crystal structure; food science; hydroxyl radicals; spectral analysis; superoxide anion; technology; temperature; thermal analysis; thermal stability; xylan
Abstract:
... The present study focussed on a novel phosphorylated corn straw xylans (XYCS‐P) that had excellent thermal stability, crystallinity and functional activity and could be potentially used as functional agents in food products. In this work, the phosphorylated derivative XYCS‐P was successfully prepared, and the chemical characterisation, spectral analysis, thermal analysis, morphology analysis, anti ...
DOI:
10.1111/ijfs.15428

15. Exploring the pharmacognostic properties and pharmacological activities of phytocompounds present in Ficus racemosa linn.: A concise review

Author:
Nilanjan Pahari; Subhabrota Majumdar; Dipanjan Karati; Rana Mazumder
Source:
Pharmacological research 2022 v.4 pp. 100137
ISSN:
2667-1425
Subject:
Ficus racemosa; analgesics; antineoplastic activity; antioxidant activity; cognition; figs; habitats; larvicides; nematicides; research; therapeutics; China; India; Malaysia; Pakistan; Sri Lanka
Abstract:
... The genus Ficus is a very useful and significant group of trees with various therapeutic properties. Ficus racemosa linn. is a standard-sized tree in the Moraceae family, often known as the cluster fig tree. Ficus racemosa is also known as yajnayoga, udumbara, goolar, dumar, bodda, heibong, jantuphalam, dimri, yogga dumur, and many more names. Ficus racemosa may be found in various countries, incl ...
DOI:
10.1016/j.prmcm.2022.100137

16. Extraction of Zanthoxylum seed protein and identification of its simulated digestion products

Author:
Qingying Luo; Xiaomeng Li; Zhiqing Zhang; Anjun Chen; Shanshan Li; Guanghui Shen; Meiliang Li; Xingyan Liu; Xueqin Yin; Lan Cheng; Xingpan Yang; Chunping Jiang; Jianlong Li; Xiaoyan Hou
Source:
Lebensmittel-Wissenschaft + Technologie 2022 v.161 pp. 113412
ISSN:
0023-6438
Subject:
Zanthoxylum bungeanum; antibacterial properties; antineoplastic activity; antioxidant activity; antioxidants; antiviral properties; bioinformatics; byproducts; chemical precipitation; digestion; drugs; in vitro digestion; molecular weight; pH; peptides; temperature
Abstract:
... Zanthoxylum bungeanum seed is the main by-product of Z. bungeanum processing, which is rich in protein. In this study, Z. bungeanum seed proteins were extracted by alkali-soluble acid precipitation method. The factors affecting the protein yield were ranked as follows: alkali dissolution temperature > extraction time > material–liquid ratio > pH. The optimal process conditions were as follows: ext ...
DOI:
10.1016/j.lwt.2022.113412

17. The Ferula Assa-foetida Essential Oil Nanoemulsion (FAEO-NE) as the Selective, Apoptotic, and Anti-Angiogenic Anticancer Compound in Human MCF-7 Breast Cancer Cells and Murine Mammary Tumor Models

Author:
Hanieh Azani; Masoud Homayouni Tabrizi; Ali Neamati; Farzanehsadat Khadem; Niloufar Khatamian
Source:
Nutrition and cancer 2022 v.74 no.6 pp. 2196-2206
ISSN:
1532-7914
Subject:
Ferula assa-foetida; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; beverages; breast neoplasms; cytotoxicity; drug delivery systems; essential oils; humans; mammary neoplasms (animal); mice; nanoemulsions; nutrition; traditional medicine; zeta potential
Abstract:
... The Ferula assa-foetida (FA) is the healthy common-consumed anticancer beverage in Iranian folk medicine. In the current study, we aimed to produce a nanoemulsion-based drug delivery system containing FA essential oil (FAEO) and evaluate its antioxidant and anticancer activity on both MCF-7 cells and murine mammary cancer tissue. The FAEO-loaded nanoemulsion (FAEO-NE) was produced and characterize ...
DOI:
10.1080/01635581.2021.1985533

18. Genus Spatholobus: a comprehensive review on ethnopharmacology, phytochemistry, pharmacology, and toxicology

Author:
Yunlu Liu; Qian Xiang; Qi Liang; Jianyou Shi; Jun He
Source:
Food & function 2022 v.13 no.14 pp. 7448-7472
ISSN:
2042-650X
Subject:
Spatholobus; anemia; anti-inflammatory activity; antimicrobial properties; antineoplastic activity; antioxidant activity; drugs; flavonoids; health services; neuroprotective effect; pain; paralysis; structure-activity relationships; taxon descriptions; therapeutics; toxicity; traditional medicine
Abstract:
... Edible medicinal plants are important sources for the development of health beneficial products and drugs. Several species of the genus Spatholobus are considered as medicinal and food homologous plants in various Asian countries for the treatment of menstrual pain, anemia, paralysis, arthralgia, etc. Regarding this genus, mounting investigations on different aspects have been conducted; however, ...
DOI:
10.1039/d2fo00895e

19. Green synthesis of silver nanoparticles using Rhodiola imbricata and Withania somnifera root extract and their potential catalytic, antioxidant, cytotoxic and growth-promoting activities

Author:
Sahil Kapoor; Hemant Sood; Shweta Saxena; Om Prakash Chaurasia
Source:
Bioprocess and biosystems engineering 2022 v.45 no.2 pp. 365-380
ISSN:
1615-7591
Subject:
Hordeum vulgare; Rhodiola; Withania somnifera; agricultural industry; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; bioprocessing; carotenoids; cell lines; cell viability; chlorophyll; cytotoxicity; dose response; germination; nanosilver; neoplasm cells; p-nitrophenol; photosynthesis; pollutants; pollution; remediation; root extracts; silver nitrate; sustainable technology; zeta potential
Abstract:
... This study presents the development of a sustainable production process of environmentally benign silver nanoparticles (AgNPs) from aqueous root extract of Rhodiola imbricata (RI) and Withania somnifera (WS) for mitigating environmental pollution and investigating their potential applications in agriculture and biomedical industry. RIWS-AgNPs were characterized using several analytical techniques ...
DOI:
10.1007/s00449-021-02666-9

20. Isolation of Sesquiterpene Lactones and the Antioxidant and Anticancer Activities of Crude Extracts from Cyanthillium cinereum

Author:
J. Dharani; S. Ravi
Source:
Chemistry of natural compounds 2022 v.58 no.1 pp. 40-46
ISSN:
0009-3130
Subject:
Cyanthillium cinereum; DNA replication; antineoplastic activity; antioxidant activity; antioxidants; cell lines; cytotoxicity; interphase; sesquiterpenoid lactones
Abstract:
... Three sesquiterpene lactones has been isolated from Cyanthillium cinereum (L.) H. Rob. by bioactivity guided assay and characterized by spectral methods as compounds 1, 2, and 3. The in vitro anticancer activity was tested against 786-O, MCF-7, and K562 cells by the MTT assay. Compound 1 showed IC₅₀ values of 12.5 and 10.4 μg/mL against 786-O cell line after 48 and 72 h, respectively, and matches ...
DOI:
10.1007/s10600-022-03593-1