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1. Air pollution and health impacts during the COVID-19 lockdowns in Grenoble, France

Author:
Marie-Laure Aix; Pascal Petit; Dominique J. Bicout
Source:
Environmental pollution 2022 v.303 pp. 119134
ISSN:
0269-7491
Subject:
COVID-19 infection; air; air pollution; air quality; asthma; children; human health; low birth weight; lung neoplasms; mortality; public health; traffic; France
Abstract:
... It is undeniable that exposure to outdoor air pollution impacts the health of populations and therefore constitutes a public health problem. Any actions or events causing variations in air quality have repercussions on populations’ health. Faced with the worldwide COVID-19 health crisis that began at the end of 2019, the governments of several countries were forced, in the beginning of 2020, to pu ...
DOI:
10.1016/j.envpol.2022.119134

2. Association between prenatal metal exposure and adverse respiratory symptoms in childhood

Author:
Nia McRae; Chris Gennings; Nadya Rivera Rivera; Marcela Tamayo-Ortiz; Ivan Pantic; Chitra Amarasiriwardena; Lourdes Schnaas; Rosalind Wright; Martha M. Tellez-Rojo; Robert O. Wright; Maria José Rosa
Source:
Environmental research 2022 v.205 pp. 112448
ISSN:
0013-9351
Subject:
asthma; blood; childhood; children; education; lead; manganese; maternal exposure; obesity; odds ratio; research; second hand smoke; statistical models; surveys; Mexico
Abstract:
... Manganese and lead have been cross-sectionally associated with adverse respiratory outcomes in childhood but there is limited data on their combined effects starting in utero. We examined associations between in utero exposure to metals and childhood respiratory symptoms. We assessed 633 mother-child dyads enrolled in the Programming Research in Obesity, Growth, Environment, and Social Stressors ( ...
DOI:
10.1016/j.envres.2021.112448

3. Association of ambient extreme heat with pediatric morbidity: a scoping review

Author:
Danielle Uibel; Rachit Sharma; Danielle Piontkowski; Perry E. Sheffield; Jane E. Clougherty
Source:
International journal of biometeorology 2022 v.66 no.8 pp. 1683-1698
ISSN:
0020-7128
Subject:
asthma; bioclimatology; childhood; children; climate change; cystic fibrosis; diabetes mellitus; diarrhea; digestion; electrolytes; heat; kidney diseases; mental health; morbidity; nationalities and ethnic groups
Abstract:
... Global climate change is leading to higher ambient temperatures and more frequent heatwaves. To date, impacts of ambient extreme heat on childhood morbidity have been understudied, although—given children’s physiologic susceptibility, with smaller body surface-to-mass ratios, and many years of increasing temperatures ahead—there is an urgent need for better information to inform public health poli ...
DOI:
10.1007/s00484-022-02310-5

4. Association of per- and polyfluoroalkyl substances with thyroid homeostasis during pregnancy in the SELMA study

Author:
Arash Derakhshan; Andreas Kortenkamp; Huan Shu; Maarten A.C. Broeren; Christian H. Lindh; Robin P. Peeters; Carl-Gustaf Bornehag; Barbara Demeneix; Tim I.M. Korevaar
Source:
Environment international 2022 v.167 pp. 107420
ISSN:
0160-4120
Subject:
asthma; blood serum; children; environment; gestational age; homeostasis; humans; pregnancy; triiodothyronine
Abstract:
... To investigate the association of exposure to per- and polyfluoroalkyl substances (PFAS) during early pregnancy with markers of the maternal thyroid system. Serum concentrations of seven PFAS as well as thyroid stimulating hormone (TSH), free and total thyroxine (FT4 and TT4), free and total triiodothyronine (FT3 and TT3) were measured in pregnant women in early pregnancy in the Swedish Environmen ...
DOI:
10.1016/j.envint.2022.107420

5. Atopic heredity modifies the association between maternal vitamin D status in pregnancy and the risk of atopic disease in childhood: an observational study

Author:
Anna Amberntsson; Ellinor Carlson Kjellberg; Jenny van Odijk; Andrea Mikkelsen; Linnea Bärebring; Hanna Augustin
Source:
Nutrition journal 2022 v.21 no.1 pp. 32
ISSN:
1475-2891
Subject:
asthma; blood serum; childhood; children; eczema; food allergies; food frequency questionnaires; inheritance (genetics); observational studies; pregnancy; regression analysis; risk
Abstract:
... BACKGROUND: The relationship between maternal vitamin D status in pregnancy and the development of atopic diseases in the offspring has been frequently studied, but with contradictory results. Previous studies have found an inverse relation between maternal vitamin D in pregnancy and the risk of atopic diseases in the child. In contrast, others have found a higher maternal 25OHD to be related to a ...
DOI:
10.1186/s12937-022-00787-9

6. Maternal diet during pregnancy and risk of allergic diseases in children up to 7–9 years old from Polish Mother and Child Cohort study

Author:
Agnieszka Brzozowska; Daniela Podlecka; Agnieszka Jankowska; Anna Król; Dorota Kaleta; Elżbieta Trafalska; Ewa Nowakowska-Świrta; Paweł Kałużny; Wojciech Hanke; Katarzyna Bal-Gierańczyk; Małgorzata Kowalska; Kinga Polańska; Joanna Jerzyńska
Source:
Environmental research 2022 v.208 pp. 112682
ISSN:
0013-9351
Subject:
Adequate Intakes; allergic rhinitis; ascorbic acid; asthma; atopic dermatitis; childhood; children; cohort studies; eating habits; food allergies; food frequency questionnaires; magnesium; maternal nutrition; pregnancy; public health; research; risk; vitamin E
Abstract:
... The impact of maternal diet during pregnancy on the risk of allergic diseases in childhood is an increasing scientific and public health concern. We evaluated the associations of maternal type of diet and essential elements and vitamins intake during pregnancy with offspring allergic and respiratory outcomes. The study population included 557 mother-child pairs from Polish Mother and Child Cohort ...
DOI:
10.1016/j.envres.2022.112682

7. Maternal pesticides exposure in pregnancy and the risk of wheezing in infancy: A prospective cohort study

Author:
Silvia Maritano; Giovenale Moirano; Maja Popovic; Antonio D'Errico; Franca Rusconi; Milena Maule; Lorenzo Richiardi
Source:
Environment international 2022 v.163 pp. 107229
ISSN:
0160-4120
Subject:
arable soils; asthma; atopy; children; cohort studies; conservation buffers; education; environment; fruits; infancy; inventories; land cover; pesticides; pet ownership; pregnancy; risk
Abstract:
... Pesticide exposure in pregnancy may have health effects in the offspring. We studied whether maternal pesticides exposure during pregnancy is associated with infant wheezing. The study involved 5997 children from the Italian NINFEA birth cohort, whose mothers were recruited during pregnancy between 2005 and 2016. We used questionnaires completed during pregnancy and 6 months after delivery to deri ...
DOI:
10.1016/j.envint.2022.107229

8. Oral cavity response to air pollutant exposure and association with pulmonary inflammation and symptoms in asthmatic children

Author:
Linchen He; Christina Norris; Xiaoxing Cui; Zhen Li; Karoline K. Barkjohn; Yanbo Teng; Lin Fang; Lili Lin; Qian Wang; Xiaojian Zhou; Jianguo Hong; Feng Li; Yinping Zhang; James J. Schauer; Marilyn Black; Michael H. Bergin; Junfeng (Jim) Zhang
Source:
Environmental research 2022 v.206 pp. 112275
ISSN:
0013-9351
Subject:
air pollutants; air pollution; asthma; biomarkers; childhood; children; inflammation; interleukin-6; malondialdehyde; mouth; nitric oxide; oxidative stress; ozone; particulates; research; saliva
Abstract:
... Exposure to fine particulate matter (PM₂.₅) and ozone (O₃) may lead to inflammation and oxidative damage in the oral cavity, which is hypothesized to contribute to the worsening of airway inflammation and asthma symptoms. In this panel study of 43 asthmatic children aged 5–13 years old, each child had 4 clinic visits with a 2-week interval between two consecutive visits. At each visit, saliva samp ...
DOI:
10.1016/j.envres.2021.112275

9. Prenatal Fine Particulate Matter, Maternal Micronutrient Antioxidant Intake, and Early Childhood Repeated Wheeze: Effect Modification by Race/Ethnicity and Sex

Author:
Yueh-Hsiu Mathilda Chiu; Kecia N. Carroll; Brent A. Coull; Srimathi Kannan; Ander Wilson; Rosalind J. Wright
Source:
Antioxidants 2022 v.11 no.2 pp. -
ISSN:
2076-3921
Subject:
Bayesian theory; antioxidants; asthma; childhood; children; education; fetal development; food frequency questionnaires; magnesium; models; oxidative stress; particulates; pregnancy; satellites; selenium; temperature; zinc
Abstract:
... Fine particulate matter (PM₂.₅) potentiates in utero oxidative stress influencing fetal development while antioxidants have potential protective effects. We examined associations among prenatal PM₂.₅, maternal antioxidant intake, and childhood wheeze in an urban pregnancy cohort (n = 530). Daily PM₂.₅ exposure over gestation was estimated using a satellite-based spatiotemporally resolved model. Mo ...
DOI:
10.3390/antiox11020366

10. Association of phthalate exposure with thyroid function during pregnancy

Author:
Arash Derakhshan; Huan Shu; Maarten A.C. Broeren; Christian H. Lindh; Robin P. Peeters; Andreas Kortenkamp; Barbara Demeneix; Carl-Gustaf Bornehag; Tim I.M. Korevaar
Source:
Environment international 2021 v.157 pp. 106795
ISSN:
0160-4120
Subject:
asthma; blood serum; children; cyclohexanes; dicarboxylic acids; environment; humans; metabolites; phthalates; pregnancy; thyroid function; triiodothyronine
Abstract:
... The extent of thyroid disruptive effects of phthalates during pregnancy remains unclear. To investigate the association of maternal urinary phthalates with markers of the thyroid system during early pregnancy. Urinary concentrations of phthalate metabolites and serum concentrations of thyroid stimulating hormone (TSH), free and total thyroxine (FT4 and TT4) and free and total triiodothyronine (FT3 ...
DOI:
10.1016/j.envint.2021.106795

11. DNA methylation at GRIN2B partially mediates the association between prenatal bisphenol F exposure and cognitive functions in 7-year-old children in the SELMA study

Author:
Elin Engdahl; Katherine Svensson; Ping-I Daniel Lin; Ali Alavian-Ghavanini; Christian Lindh; Joëlle Rüegg; Carl-Gustaf Bornehag
Source:
Environment international 2021 v.156 pp. 106617
ISSN:
0160-4120
Subject:
DNA methylation; asthma; bisphenol F; childhood; children; cognition; environment; epigenetics; equations; genes; glutamic acid; maternal exposure; pregnancy; urine
Abstract:
... Accumulating evidence suggests that prenatal chemical exposure triggers epigenetic modifications that could influence health outcomes later in life. In this study, we investigated whether DNA methylation (DNAm) levels at the glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B) gene underlies the association between prenatal exposure to an endocrine disrupting chemical (EDC), bisphenol F (BP ...
DOI:
10.1016/j.envint.2021.106617

12. Early Life Exposure to Tris(2-butoxyethyl) Phosphate (TBOEP) Is Related to the Development of Childhood Asthma

Author:
Garthika Navaranjan; Liisa M. Jantunen; Miriam L. Diamond; Shelley A. Harris; Sarah Bernstein; James A. Scott; Tim K. Takaro; Ruixue Dai; Diana L. Lefebvre; Piush J. Mandhane; Theo J. Moraes; Elinor Simons; Stuart E. Turvey; Malcolm R. Sears; Padmaja Subbarao; Jeffrey R. Brook
Source:
Environmental science & technology letters 2021 v.8 no.7 pp. 531-537
ISSN:
2328-8930
Subject:
asthma; childhood; children; cohort studies; dose response; dust; environmental science; organophosphorus compounds; phosphates; regression analysis; technology
Abstract:
... We investigated the association between exposure to 29 organophosphate esters (OPEs) and the onset of childhood asthma and recurrent wheeze. Using a case-cohort design nested in the Canadian CHILD Cohort Study, we included a random sample of children (n = 429), all children with asthma at 5 years (n = 128), and all children with recurrent wheeze between 2 and 5 years (n = 331). The association bet ...
DOI:
10.1021/acs.estlett.1c00210

13. Early postnatal exposure to traffic-related air pollution and asthma in adolescents: vulnerability factors in the PARIS birth cohort

Author:
Antoine Citerne; Célina Roda; Malika Viola; Fanny Rancière; Isabelle Momas
Source:
Environmental research 2021 v.201 pp. 111473
ISSN:
0013-9351
Subject:
adolescence; air; air pollution; asthma; children; confidence interval; models; morbidity; nitrogen; nitrogen dioxide; odds ratio; regression analysis; research; respiratory system; rhinitis
Abstract:
... Associations between early traffic-related air pollution (TRAP) exposure and respiratory and allergic morbidity in adolescents are inconsistent. However, sub-groups might be more vulnerable to the health effects of this exposure.We investigated associations between early exposure to TRAP and respiratory and allergic morbidity at age 13 years in the PARIS birth cohort, and potential modifying effec ...
DOI:
10.1016/j.envres.2021.111473

14. Examining Associations Between Dietary Inflammatory Index in Pregnancy, Pro-inflammatory Cytokine and Chemokine Levels at Birth, and Offspring Asthma and/or Wheeze by Age 4 Years

Author:
Carina Venter; Michaela P. Palumbo; Katherine A. Sauder; Deborah H. Glueck; Anne P. Starling; Brandy M. Ringham; Liam O’Mahony; Brianna F. Moore; Ivana V. Yang; Dana Dabelea
Source:
Journal of the Academy of Nutrition and Dietetics 2021 v.121 no.10 pp. 2003-2012.e3
ISSN:
2212-2672
Subject:
asthma; chemokine CCL2; children; dietetics; interleukin-10; interleukin-4; interleukin-6; interleukin-8; longitudinal studies; maternal nutrition; models; nationalities and ethnic groups; necrosis; neoplasms; odds ratio; pregnancy; regression analysis; Colorado
Abstract:
... Few studies have demonstrated associations between maternal dietary inflammatory index (DII) during pregnancy and offspring asthma and/or wheeze.The study aimed to assess associations between maternal DII during pregnancy and 1) offspring cord sera pro-inflammatory cytokines (interleukin [IL]-1β, IL-4, IL-6, IL-10, tumor necrosis factor-α) and chemokines (IL-8, monocyte chemoattractant protein-1) ...
DOI:
10.1016/j.jand.2021.02.015

15. Factors Associated with the Initiation of Added Sugar among Low-Income Young Children Participating in the Special Supplemental Nutrition Program for Women, Infants, and Children in the US

Author:
Morium B. Bably; Rajib Paul; Sarah B. Laditka; Elizabeth F. Racine
Source:
Nutrients 2021 v.13 no.11 pp. -
ISSN:
2072-6643
Subject:
added sugars; apples; asthma; blood pressure; caregivers; children; desserts; education; employment; models; nationalities and ethnic groups; overweight; premature birth; syrups; taste; yogurt
Abstract:
... Added sugar intake at a young age is associated with chronic diseases including cardiovascular diseases, asthma, elevated blood pressure, and overweight. The Dietary Guidelines for Americans 2020–2025 and the American Heart Association recommend delaying the introduction of added sugar until age 2. The aims of this study were to identify the timing of added sugar initiation; factors associated wit ...
DOI:
10.3390/nu13113888

16. Feasibility study on exhaled-breath analysis by untargeted Selected-Ion Flow-Tube Mass Spectrometry in children with cystic fibrosis, asthma, and healthy controls: Comparison of data pretreatment and classification techniques

Author:
Karen Segers; Amorn Slosse; Johan Viaene; Michiel A.G.E. Bannier; Kim D.G. Van de Kant; Edward Dompeling; Ann Van Eeckhaut; Joeri Vercammen; Yvan Vander Heyden
Source:
Talanta 2021 v.225 pp. 122080
ISSN:
0039-9140
Subject:
asthma; biomarkers; breath tests; bronchoscopy; calibration; children; classification; cystic fibrosis; data analysis; data collection; discriminant analysis; feasibility studies; inflammation; least squares; mass spectrometry; models; patients; pretreatment; sampling; uncertainty
Abstract:
... Selected-Ion Flow-Tube Mass Spectrometry (SIFT-MS) has been applied in a clinical context as diagnostic tool for breath samples using target biomarkers. Exhaled breath sampling is non-invasive and therefore much more patient friendly compared to bronchoscopy, which is the golden standard for evaluating airway inflammation. In the actual pilot study, 55 exhaled breath samples of children with asthm ...
DOI:
10.1016/j.talanta.2021.122080

17. Fungal populations in the bedroom dust of children in Havana, Cuba, and its relationship with environmental conditions

Author:
Kenia C. Sánchez Espinosa; Teresa I. Rojas Flores; Sonia Rodríguez Davydenko; Silvia J. Venero Fernández; Michel Almaguer
Source:
Environmental science and pollution research 2021 v.28 no.38 pp. 53010-53020
ISSN:
0944-1344
Subject:
Aspergillus; Cladosporium; Coprinus; Curvularia; Penicillium; Periconia; Xylariaceae; air; asthma; childhood; children; community structure; culture media; cumulative exposure; dust; fungal communities; fungi; furniture; hyphae; microscopy; natural ventilation; pollution; regression analysis; relative humidity; research; spores; temperature; Cuba
Abstract:
... The study of the fungal community composition in house dust is useful to assess the accumulative exposure to fungi in indoor environments. The objective of this research was to characterize the fungal diversity of house dust and its association with the environmental conditions of bedrooms. For this, the dust was collected from 41 bedrooms of children between the ages of 8 and 9 with a family hist ...
DOI:
10.1007/s11356-021-14231-8

18. Landscapes of becoming social: A systematic review of evidence for associations and pathways between interactions with nature and socioemotional development in children

Author:
Lærke Mygind; Mette Kurtzhals; Clare Nowell; Paulina S. Melby; Matt P. Stevenson; Mark Nieuwenhuijsen; Jarrad A.G. Lum; Trine Flensborg-Madsen; Peter Bentsen; Peter G. Enticott
Source:
Environment international 2021 v.146 pp. 106238
ISSN:
0160-4120
Subject:
air pollution; asthma; children; cognition; emotions; environment; experimental design; green infrastructure; obesity; risk; systematic review
Abstract:
... Existing research indicates that spending time in nature is associated with diverse aspects of children’s health and wellbeing. Although fundamental to later life chances and health, no systematic reviews, to our knowledge, have focused specifically on the effects of interaction with nature on socioemotional functioning in childhood.Amongst children, what is the consistency of associations between ...
DOI:
10.1016/j.envint.2020.106238

19. Nutrition, Obesity and Asthma Inception in Children. The Role of Lung Function

Author:
Sanchez-Solís Manuel; García-Marcos Luis
Source:
Nutrients 2021 v.13 no.11 pp. -
ISSN:
2072-6643
Subject:
adipokines; asthma; childhood; children; chronic diseases; cytokines; early development; epidemiology; inflammation; insulin resistance; lung function; lungs; nutrition; public health
Abstract:
... Obesity is an important public health problem. WHO estimates that about 39 million children younger than 5 years of age are overweighted or obese. On the other hand, asthma is the most prevalent chronic disease in childhood, and thus, many children share those two conditions. In the present paper we review the epidemiology of children with asthma and obesity, as well as the consequences of being o ...
DOI:
10.3390/nu13113837

20. Potential health benefits of sustained air quality improvements in New York City: A simulation based on air pollution levels during the COVID-19 shutdown

Author:
Frederica Perera; Alique Berberian; David Cooley; Elizabeth Shenaut; Hollie Olmstead; Zev Ross; Thomas Matte
Source:
Environmental research 2021 v.193 pp. 110555
ISSN:
0013-9351
Subject:
COVID-19 infection; adults; air; air pollution; air quality; asthma; autism; children; climate; death; economic recovery; hospitals; infant mortality; low birth weight; particulates; premature birth; public health; research; transportation; New York
Abstract:
... New York City (NYC) experienced a sharp decline in air pollution during the COVID-19 shutdown period (March 15, 2020 to May 15, 2020)—albeit at high social and economic costs. It provided a unique opportunity to simulate a scenario in which the city-wide air quality improvement during the shutdown were sustained over the five-year period, 2021 through 2025, allowing us to estimate the potential pu ...
DOI:
10.1016/j.envres.2020.110555

21. Prenatal and early life exposure to particulate matter, environmental tobacco smoke and respiratory symptoms in Mexican children

Author:
Nadya Y. Rivera Rivera; Marcela Tamayo-Ortiz; Adriana Mercado García; Allan C. Just; Itai Kloog; Martha Maria Téllez-Rojo; Robert O. Wright; Rosalind J. Wright; Maria José Rosa
Source:
Environmental research 2021 v.192 pp. 110365
ISSN:
0013-9351
Subject:
air pollution; asthma; birth weight; caregivers; children; conception; cumulative risk; education; models; morbidity; obesity; particulates; pregnancy; research; satellites; second hand smoke; Mexico
Abstract:
... Exposure to particulate matter <2.5 μm in diameter (PM₂.₅) and environmental tobacco smoke (ETS) are associated with respiratory morbidity starting in utero. However, their potential synergistic effects have not been completely elucidated. Here, we examined the joint effects of prenatal and early life PM₂.₅ and prenatal ETS exposure on respiratory outcomes in children.We studied 536 mother-child d ...
DOI:
10.1016/j.envres.2020.110365

22. Prenatal exposure to bisphenols and cognitive function in children at 7 years of age in the Swedish SELMA study

Author:
Carl-Gustaf Bornehag; Elin Engdahl; Maria Unenge Hallerbäck; Sverre Wikström; Christian Lindh; Joëlle Rüegg; Eva Tanner; Chris Gennings
Source:
Environment international 2021 v.150 pp. 106433
ISSN:
0160-4120
Subject:
asthma; bisphenol A; bisphenol F; bisphenol S; children; cognition; environment; maternal exposure; memory; neurodevelopment
Abstract:
... Experimental evidence demonstrates that exposure to bisphenol A (BPA), and the recently introduced alternatives bisphenol S (BPS) and bisphenol F (BPF) alter normal neurodevelopment. More research is needed to evaluate the associations between exposure to individual BPA alternatives and neurodevelopmental outcomes in humans.The present study aimed at examining the individual associations between p ...
DOI:
10.1016/j.envint.2021.106433

23. Role of endogenous melatonin in pathophysiologic and oxidative stress responses to personal air pollutant exposures in asthmatic children

Author:
Linchen He; Christina Norris; Xiaoxing Cui; Zhen Li; Karoline K. Barkjohn; Yanbo Teng; Lin Fang; Lili Lin; Qian Wang; Xiaojian Zhou; Jianguo Hong; Feng Li; Yinping Zhang; James J. Schauer; Marilyn Black; Michael H. Bergin; Junfeng (Jim) Zhang
Source:
Science of the total environment 2021 v.773 pp. 145709
ISSN:
0048-9697
Subject:
air pollutants; air pollution; asthma; biomarkers; children; environment; excretion; inflammation; lung function; lungs; malondialdehyde; melatonin; nitric oxide; oxidative stress; ozone; pathophysiology; urine
Abstract:
... Heightening oxidative stress and inflammation is an important pathophysiological mechanism underlying air pollution health effects in people with asthma. Melatonin can suppress oxidative stress and inflammation in pulmonary and circulatory systems. However, the role of melatonin in the oxidative stress and physiological responses to air pollution exposure has not been examined in children with ast ...
DOI:
10.1016/j.scitotenv.2021.145709

24. Aeroallergen sensitization in Lebanese asthmatic children: the results of a cohort national study

Author:
Hala Feghali Abiad; Valeria Modica Alameddine; Souheil Hallit; Paul-Henry Torbey; Salman Mroueh; Nelly Yazbek; Edgard Asmar; Pierre Hage; George Abi Fares; Marie Samarani; Marie-Claude Fadous Khalife
Source:
Environmental science and pollution research international 2020 v.27 no.5 pp. 5597-5605
ISSN:
0944-1344
Subject:
Alternaria; Anthoxanthum odoratum; Aspergillus fumigatus; Blattella germanica; Cupressaceae; Dactylis glomerata; Dermatophagoides pteronyssinus; Lolium; Parietaria; allergens; altitude; asthma; barley; childhood; children; corn; dogs; dust mites; grasses; meadows; national surveys; oats; olives; patients; prognosis; skin prick tests; wheat; Lebanon
Abstract:
... Atopic asthma is characterized by the presence of sensitization to common aeroallergens, which tends to have a worse prognosis than non-atopic asthma. The objectives were to determine the prevalence of aeroallergens sensitization in the Lebanese pediatric asthmatic population and determine the relationship between allergens sensitization (indoor and outdoor) and age, area of residence and altitude ...
DOI:
10.1007/s11356-019-07234-z

25. Air pollution from industries and asthma onset in childhood: A population-based birth cohort study using dispersion modeling

Author:
Stéphane Buteau; Maryam Shekarrizfard; Marianne Hatzopolou; Philippe Gamache; Ling Liu; Audrey Smargiassi
Source:
Environmental research 2020 v.185 pp. 109180
ISSN:
0013-9351
Subject:
air pollutants; air pollution; algorithms; asthma; childhood; children; cohort studies; databases; emissions; industry; models; nitrogen dioxide; particulates; risk; sulfur dioxide; Quebec
Abstract:
... Despite evidence that ambient air pollution may play a role in the development of asthma, little is known about the potential contribution of industrial emissions.We used a population-based birth cohort to investigate the association between asthma onset in childhood and residential exposure to industrial emissions, estimated from atmospheric dispersion modeling.The study population comprised all ...
DOI:
10.1016/j.envres.2020.109180

26. Allergen-specific immunotherapy, novel drugs and biologicals: hopes from the difficult-to-treat allergic child

Author:
Carla Mastrorilli; Angelica Santoro; Carlo Caffarelli
Source:
Aerobiologia 2020 v.36 no.1 pp. 95-98
ISSN:
0393-5965
Subject:
allergens; asthma; atopic dermatitis; childhood; children; diagnostic techniques; drugs; immunotherapy; monoclonal antibodies; patients; phenotype; urticaria
Abstract:
... In the last decades, significant progresses have been reached in the management of atopic diseases in childhood. Several approaches have been proposed in patients affected by moderate-to-severe atopic diseases. Severe asthma and atopic dermatitis are poorly known with different underlying phenotypes and endotypes, and they may require further cares with biological therapies. Omalizumab, anti-IgE m ...
DOI:
10.1007/s10453-019-09573-3

27. Ambient daily pollen levels in association with asthma exacerbation among children in Philadelphia, Pennsylvania

Author:
Anneclaire J. De Roos; Chén C. Kenyon; Yuzhe Zhao; Kari Moore; Steve Melly; Rebecca A. Hubbard; Sarah E. Henrickson; Christopher B. Forrest; Ana V. Diez Roux; Mitchell Maltenfort; Leah H. Schinasi
Source:
Environment international 2020 v.145 pp. 106138
ISSN:
0160-4120
Subject:
allergic rhinitis; asthma; children; environment; grasses; hospitals; human health; nationalities and ethnic groups; pollen; regression analysis; relative humidity; telemedicine; temperature; trees; vegetation; Pennsylvania
Abstract:
... Pollen from trees, grasses, and weeds can trigger asthma exacerbation in sensitized individuals. However, there are gaps in knowledge about the effects, such as the relative risks from different plant taxa and threshold levels of effect. We aimed to describe the local association between pollen and asthma exacerbation among children in the City of Philadelphia, and to evaluate whether effects are ...
DOI:
10.1016/j.envint.2020.106138

28. Anthropogenic or non-anthropogenic particulate matter: Which one is more dangerous and how to differentiate between the effects?

Author:
Lena Novack; Yorye Shenkar; Alexandra Shtein; Itai Kloog; Batia Sarov; Victor Novack
Source:
Chemosphere 2020 v.240 pp. 124954
ISSN:
0045-6535
Subject:
anthropogenic activities; asthma; chemical composition; children; models; monitoring; nitrogen dioxide; particulates; pollutants
Abstract:
... The authors have observed that the function linking health outcomes with exposure to particulate-matter (PM) follows a biphasic pattern. It peaks around levels of PM10≤100 μg/m3, then weakens and rises again at PM10 levels in the range of hundreds. This could be due to a different nature of PM, the first peak reflecting a stronger anthropogenic and the second - weaker non-anthropogenic particles' ...
DOI:
10.1016/j.chemosphere.2019.124954

29. Apoptosis of Eosinophil Granulocytes

Author:
Martina Zustakova; Lucie Kratochvilova; Petr Slama
Source:
Biology 2020 v.9 no.12 pp. -
ISSN:
2079-7737
Subject:
adults; apoptosis; asthma; children; dermatitis; eosinophilia; eosinophils; food allergies; glucocorticoids; half life; infants; inflammation; knowledge; medicine; people; pollen; Czech Republic
Abstract:
... In the past 10 years, the number of people in the Czech Republic with allergies has doubled to over three million. Allergic pollen catarrh, constitutional dermatitis and asthma are the allergic disorders most often diagnosed. Genuine food allergies today affect 6–8% of nursing infants, 3–5% of small children, and 2–4% of adults. These disorders are connected with eosinophil granulocytes and their ...
DOI:
10.3390/biology9120457

30. Assessment of Hymenoptera and Non-Hymenoptera Insect Bite and Sting Allergy Among Patients of Tropical Region of West Bengal, India

Author:
Arghya Laha; Tania Sarkar; Debarati Dey; Priti Mondal; Srijit Bhattacharya; Saibal Moitra; Goutam Kumar Saha; Sanjoy Podder; David Florin
Source:
Journal of medical entomology 2020 v.57 no.1 pp. 1-7
ISSN:
1938-2928
Subject:
Aedes aegypti; Apis cerana indica; Formica fusca; Lasius niger; Musca domestica; Periplaneta americana; Solenopsis invicta; Vespula vulgaris; adolescents; adults; allergens; asthma; bites and stings; children; farmers; females; fire ants; grasshoppers; humans; males; occupations; patients; skin prick tests; tropics; venoms; worker honey bees; India
Abstract:
... West Bengal, India, is inhabited by abundance and variety of insects that triggers sensitization in some humans to inhalant allergens and/or insect stings/venoms. Lack of research on this topic prevented accurate diagnosis and proper follow-up treatments to patients suffering from insect-induced allergies. The aim of our study was to identify the allergy-causing insects and evaluate resulting sens ...
DOI:
10.1093/jme/tjz088

31. Association of urinary levels of bisphenols F and S used as bisphenol A substitutes with asthma and hay fever outcomes

Author:
Angelico Mendy; Pӓivi M. Salo; Jesse Wilkerson; Lydia Feinstein; Kelly K. Ferguson; Michael B. Fessler; Peter S. Thorne; Darryl C. Zeldin
Source:
Environmental research 2020 v.183 pp. 108944
ISSN:
0013-9351
Subject:
National Health and Nutrition Examination Survey; asthma; bisphenol A; bisphenol S; children; confidence interval; data analysis; hay fever; men; odds ratio; products and commodities; prospective studies; regression analysis; urine; United States
Abstract:
... Bisphenols F (BPF) and S (BPS) are bisphenol A (BPA) analogs used as substitutes in consumer products. Despite previous reports of BPA's association with asthma, no studies have examined its structural analogs in relation to asthma and allergy outcomes.To examine the association of urinary BPF, BPS, and BPA with asthma and hay fever in a US representative sample.We analyzed data from 3,538 partici ...
DOI:
10.1016/j.envres.2019.108944
PubMed:
31911000
PubMed Central:
PMC7167336

32. Associations between air pollution and pediatric eczema, rhinoconjunctivitis and asthma: A meta-analysis of European birth cohorts

Author:
Elaine Fuertes; Jordi Sunyer; Ulrike Gehring; Daniela Porta; Francesco Forastiere; Giulia Cesaroni; Martine Vrijheid; Mònica Guxens; Isabella Annesi-Maesano; Rémy Slama; Dieter Maier; Manolis Kogevinas; Jean Bousquet; Leda Chatzi; Aitana Lertxundi; Mikel Basterrechea; Ana Esplugues; Amparo Ferrero; John Wright; Dan Mason; Rosie McEachan; Judith Garcia-Aymerich; Bénédicte Jacquemin
Source:
Environment international 2020 v.136 pp. 105474
ISSN:
0160-4120
Subject:
absorbance; adverse effects; air pollution; asthma; children; confidence interval; eczema; exposure models; meta-analysis; nitrogen dioxide; odds ratio; particulates; regression analysis
Abstract:
... Uncertainly continues to exist regarding the role of air pollution on pediatric asthma and allergic conditions, especially as air pollution levels have started to decrease in recent decades.We examined associations of long-term air pollution levels at the home address with pediatric eczema, rhinoconjunctivitis and asthma prevalences in five birth cohorts (BIB, EDEN, GASPII, RHEA and INMA) from sev ...
DOI:
10.1016/j.envint.2020.105474

33. Associations of personal exposure to air pollutants with airway mechanics in children with asthma

Author:
Linchen He; Zhen Li; Yanbo Teng; Xiaoxing Cui; Karoline K. Barkjohn; Christina Norris; Lin Fang; Lili Lin; Qian Wang; Xiaojian Zhou; Jianguo Hong; Feng Li; Yinping Zhang; James J. Schauer; Marilyn Black; Michael H. Bergin; Junfeng (Jim) Zhang
Source:
Environment international 2020 v.138 pp. 105647
ISSN:
0160-4120
Subject:
air; air flow; air pollutants; air pollution; air quality; asthma; blood; children; filtration; inflammation; lung function; models; ozone; particulates; suburban areas; China
Abstract:
... The importance of airway mechanics has been increasingly recognized in pediatric asthma. However, no studies have examined responses of airway mechanics to air pollution exposure in asthmatic children.In this panel study involving indoor air filtration manipulation that created a large gradient of personal exposure to PM₂.₅, the airway mechanics and lung function of 43 asthmatic children 5–13 year ...
DOI:
10.1016/j.envint.2020.105647

34. Bayesian analysis of the short-term association of NO2 exposure with local burden of asthmatic symptoms in children

Author:
Vera van Zoest; Gerard Hoek; Frank Osei; Alfred Stein
Source:
Science of the total environment 2020 v.720 pp. 137544
ISSN:
0048-9697
Subject:
Bayesian theory; acute exposure; air pollution; air quality; asthma; burden of disease; children; cough; drug therapy; kriging; meta-analysis; models; nitrogen dioxide; odds ratio; Netherlands
Abstract:
... Short-term exposure to air pollution has been associated with exacerbation of respiratory diseases such as asthma. Substantial heterogeneity in effect estimates has been observed between previous studies. This study aims to quantify the local burden of daily asthma symptoms in asthmatic children in a medium-sized city. Air pollution exposure was estimated using the nearest sensor in a fine resolut ...
DOI:
10.1016/j.scitotenv.2020.137544

35. Benefits of influenza vaccination on the associations between ambient air pollution and allergic respiratory diseases in children and adolescents: New insights from the Seven Northeastern Cities study in China

Author:
Kangkang Liu; Shanshan Li; Zhengmin (Min) Qian; Shyamali C. Dharmage; Michael S. Bloom; Joachim Heinrich; Bin Jalaludin; Iana Markevych; Lidia Morawska; Luke D. Knibbs; Leslie Hinyard; Hong Xian; Shan Liu; Shao Lin; Ari Leskinen; Mika Komppula; Pasi Jalava; Marjut Roponen; Li-Wen Hu; Xiao-Wen Zeng; Wenbiao Hu; Gongbo Chen; Bo-Yi Yang; Yuming Guo; Guang-Hui Dong
Source:
Environmental pollution 2020 v.256 pp. 113434
ISSN:
0269-7491
Subject:
adolescents; aerodynamics; air pollutants; air pollution; allergic rhinitis; artificial intelligence; asthma; childhood; children; chronic exposure; cities; cross-sectional studies; influenza vaccination; influenza vaccines; issues and policy; models; nitrogen dioxide; particulates; questionnaires; risk; schools; surveys; China
Abstract:
... Little information exists on interaction effects between air pollution and influenza vaccination on allergic respiratory diseases. We conducted a large population-based study to evaluate the interaction effects between influenza vaccination and long-term exposure to ambient air pollution on allergic respiratory diseases in children and adolescents.A cross-sectional study was investigated during 20 ...
DOI:
10.1016/j.envpol.2019.113434

36. Body composition in children with chronic inflammatory diseases: A systematic review

Author:
Noora Houttu; Marko Kalliomäki; Minna-Maija Grönlund; Harri Niinikoski; Merja Nermes; Kirsi Laitinen
Source:
Clinical nutrition 2020 v.39 no.9 pp. 2647-2662
ISSN:
0261-5614
Subject:
Crohn disease; adiposity; arthritis; asthma; celiac disease; children; children at risk; databases; guidelines; inflammation; juveniles; lean body mass; systematic review; ulcerative colitis
Abstract:
... Aberrations in body composition are expected in children suffering from chronic inflammatory conditions. The objective is to examine whether children with inflammatory bowel disease (IBD: Crohn's disease and ulcerative colitis), coeliac disease, asthma and juvenile idiopathic arthritis (JIA) have an altered body composition as compared to healthy children.A systematic review, registered in Prosper ...
DOI:
10.1016/j.clnu.2019.12.027

37. Characterising a Weight Loss Intervention in Obese Asthmatic Children

Author:
Shaun Eslick; Megan E. Jensen; Clare E. Collins; Peter G. Gibson; Jodi Hilton; Lisa G. Wood
Source:
Nutrients 2020 v.12 no.2 pp. -
ISSN:
2072-6643
Subject:
asthma; biomarkers; body composition; body mass index; children; duration; food intake; lung function; mass; nutrients; nutritional adequacy; nutritional intervention; obesity; objectives; physical activity; prevalence; sugars; weight loss
Abstract:
... The prevalence of obesity in asthmatic children is high and is associated with worse clinical outcomes. We have previously reported that weight loss leads to improvements in lung function and asthma control in obese asthmatic children. The objectives of this secondary analysis were to examine: (1) changes in diet quality and (2) associations between the baseline subject characteristics and the deg ...
DOI:
10.3390/nu12020507

38. Characteristics of fast food consumption among adolescents

Author:
Akmaral Baspakova; Ainur Zinalieva; Anara Abitova; Yeltay Rakhmanov
Source:
Proceedings of the Nutrition Society 2020 v.79 no.OCE2 pp. E704
ISSN:
1475-2719
Subject:
asthma; childhood; children; confidence interval; diet; digestive tract; education programs; ethics; fast foods; food consumption; nutritive value; obesity; odds ratio; questionnaires; respiratory system; risk; sugars; weight gain; Kazakhstan
Abstract:
... Special attention is paid to healthy eating in order to promote the health of children and adolescents. Eating habits are formed in childhood, respectively, a child who has eaten unhealthy food, including fast food, is at additional risk of noncommunicable diseases. Fast food is convenient and made to meet the tastes of consumers through the use of salt, sugar and fat. In addition, some ingredient ...
DOI:
10.1017/S0029665120006539

39. Cross-sectional associations between ambient air pollution and respiratory signs and symptoms among young children in Tehran

Author:
Zahra Namvar; Masud Yunesian; Mansour Shamsipour; Mohammad Sadegh Hassanvand; Kazem Naddafi; Elahe Shahhosseini
Source:
Atmospheric environment 2020 v.223 pp. 117268
ISSN:
1352-2310
Subject:
air pollutants; air pollution; air quality; asthma; boys; bronchitis; carbon monoxide; children; chronic exposure; cross-sectional studies; day care centers; guidelines; interviews; lung function; monitoring; nitrogen dioxide; particulates; questionnaires; regression analysis; sulfur dioxide
Abstract:
... Exposure to ambient air pollutants may significantly affect the incidence of respiratory symptoms and lung function in children. The present study examined the associations between exposure to ambient air pollutants and respiratory symptoms in children. In this cross-sectional study, 1070 children under the age of seven years were recruited from 61 day-care centers of Tehran in 2015. Initially, da ...
DOI:
10.1016/j.atmosenv.2020.117268

40. Dietary Habits in Children with Respiratory Allergies: A Single-Center Polish Pilot Study

Author:
Eliza Wasilewska; Sylwia Małgorzewicz; Marta Gruchała-Niedoszytko; Magdalena Skotnicka; Ewa Jassem
Source:
Nutrients 2020 v.12 no.5 pp. -
ISSN:
2072-6643
Subject:
age; allergic rhinitis; asthma; body composition; body mass index; childhood obesity; children; correlation; eating habits; food frequency questionnaires; ingestion; lung function; materials; nutrients; nutritional status; physical activity; population; prevalence; regression analysis; risk factors; skin prick tests; sweets; underweight; volume
Abstract:
... Background: The rising trend in allergic diseases has developed in parallel with the increasing prevalence of obesity, suggesting a possible association. The links between eating habits and allergies have not been sufficiently clarified. Aim: To evaluate the nutritional status, eating habits, and risk factors of obesity and pulmonary function in children with allergic rhinitis. Materials and metho ...
DOI:
10.3390/nu12051521

41. Does respiratory syncytial virus lower respiratory illness in early life cause recurrent wheeze of early childhood and asthma? Critical review of the evidence and guidance for future studies from a World Health Organization-sponsored meeting

Author:
Amanda J. Driscoll; S. Hasan Arshad; Louis Bont; Steven M. Brunwasser; Thomas Cherian; Janet A. Englund; Deshayne B. Fell; Laura L. Hammitt; Tina V. Hartert; Bruce L. Innis; Ruth A. Karron; Gayle E. Langley; E. Kim Mulholland; Patrick K. Munywoki; Harish Nair; Justin R. Ortiz; David A. Savitz; Nienke M. Scheltema; Eric A.F. Simões; Peter G. Smith; Fred Were; Heather J. Zar; Daniel R. Feikin
Source:
Vaccine 2020 v.38 no.11 pp. 2435-2448
ISSN:
0264-410X
Subject:
Respiratory syncytial virus; asthma; childhood; children; experts; infants; monoclonal antibodies; morbidity; observational studies; public health; vaccines; Switzerland
Abstract:
... Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection (LRTI) and hospitalization in infants and children globally. Many observational studies have found an association between RSV LRTI in early life and subsequent respiratory morbidity, including recurrent wheeze of early childhood (RWEC) and asthma. Conversely, two randomized placebo-controlled trials of effica ...
DOI:
10.1016/j.vaccine.2020.01.020
PubMed:
31974017
PubMed Central:
PMC7049900

42. Dynamic growth metrics for examining prenatal exposure impacts on child growth trajectories: Application to perfluorooctanoic acid (PFOA) and postnatal weight gain

Author:
Eva M. Tanner; Carl-Gustaf Bornehag; Chris Gennings
Source:
Environmental research 2020 v.182 pp. 109044
ISSN:
0013-9351
Subject:
adolescents; asthma; birth weight; body mass index; boys; childhood; children; epidemiological studies; growth models; infancy; infant growth; maternal exposure; perfluorooctanoic acid; weight gain
Abstract:
... Epidemiologic studies investigating prenatal exposures in relation to growth typically rely on cumulative growth measures such as weight or BMI. However, less is known about how prenatal exposure may impact other aspects of growth dynamics, including timing and velocity.To describe and apply a nonlinear growth model previously used in other health science fields to characterize postnatal growth tr ...
DOI:
10.1016/j.envres.2019.109044
PubMed:
31874421
PubMed Central:
PMC7027597

43. Effect modification of the short-term effects of air pollution on morbidity by season: A systematic review and meta-analysis

Author:
Stéphanie Bergmann; Bixia Li; Eva Pilot; Renchao Chen; Boguang Wang; Jun Yang
Source:
Science of the total environment 2020 v.716 pp. 136985
ISSN:
0048-9697
Subject:
adverse effects; air pollutants; air pollution; ambient temperature; asthma; carbon monoxide; children; databases; elderly; females; males; meta-analysis; morbidity; nitrogen dioxide; ozone; particulates; pneumonia; relative risk; screening; stroke; sulfur dioxide; systematic review; variance
Abstract:
... Studies of the health effects of air pollution have traditionally controlled for ambient temperature as a confounder, and vice versa. However, season might be an important factor contributing to adverse health effects of air pollution. Given the current inconsistencies in results of previous studies on the effect modification of air pollution on morbidity by season, a systematic review and meta-an ...
DOI:
10.1016/j.scitotenv.2020.136985

44. Effect of prenatal exposure to per- and polyfluoroalkyl substances on childhood allergies and common infectious diseases in children up to age 7 years: The Hokkaido study on environment and children's health

Author:
Yu Ait Bamai; Houman Goudarzi; Atsuko Araki; Emiko Okada; Ikuko Kashino; Chihiro Miyashita; Reiko Kishi
Source:
Environment international 2020 v.143 pp. 105979
ISSN:
0160-4120
Subject:
Japan; Respiratory syncytial virus; asthma; biomarkers; chickenpox; childhood; children; eczema; environment; equations; humans; immunosuppression; immunotoxicity; maternal exposure; odds ratio; perfluorooctane sulfonic acid; perfluorooctanoic acid; perfluorotridecanoic acid; pneumonia; pregnancy; questionnaires; regression analysis; relative risk; surveys; tandem mass spectrometry; ultra-performance liquid chromatography
Abstract:
... Per- and polyfluoroalkyl substances (PFAS) are widely used bio-accumulative chemicals in many industrial and household products. Experimental studies reported that exposure to PFAS results in immunotoxicity. We have previously reported that prenatal exposure to PFAS decreased the risk of allergies, while it increased the risk of infectious diseases at ages 2 and 4 years. However, it remains unclea ...
DOI:
10.1016/j.envint.2020.105979

45. Effects of variations in meteorological factors on daily hospital visits for asthma: A time-series study

Author:
Hehua Zhang; Shu Liu; Zongjiao Chen; Biao Zu; Yuhong Zhao
Source:
Environmental research 2020 v.182 pp. 109115
ISSN:
0013-9351
Subject:
adults; air pollutants; air pollution; asthma; atmospheric pressure; children; hospitals; nonlinear models; relative risk; seasonal variation; time series analysis; wind speed; China
Abstract:
... Few studies have explored the relationships between meteorological factors and asthma. This study explored the associations between daily variations in meteorological factors and hospital visits for asthma among different ages, genders, and asthma subtypes in Shenyang, China. A distributed lag non-linear model with Poisson regression was used; confounding factors included day of the week, holidays ...
DOI:
10.1016/j.envres.2020.109115

46. Excess free fructose, apple juice, high fructose corn syrup and childhood asthma risk – the National Children’s Study

Author:
Luanne R. DeChristopher; Katherine L. Tucker
Source:
Nutrition journal 2020 v.19 no.1 pp. 60
ISSN:
1475-2891
Subject:
age; antigens; apple juice; asthma; childhood; children; dietary protein; digestive system; food availability; fructose; fruit drinks; high fructose corn syrup; incidence; lungs; malabsorption; microorganisms; plateaus; prevalence; receptors; regression analysis; research; risk; soft drinks; sports
Abstract:
... BACKGROUND: Recent research provides consistent evidence that the unexplained doubling of childhood asthma prevalence (1980–1995), its continued climb and 2013 plateau, may be associated with the proliferation of high-fructose-corn-syrup (HFCS) in the US food supply. The HFCS used in soft drinks has been shown to contain a higher fructose-to-glucose ratio than previously thought. This coincides wi ...
DOI:
10.1186/s12937-020-00578-0

47. Exposure to air pollution during the first 1000 days of life and subsequent health service and medication usage in children

Author:
Jingyi Shao; Graeme R. Zosky; Amanda J. Wheeler; Shyamali Dharmage; Marita Dalton; Grant J. Williamson; Tierney O’Sullivan; Katherine Chappell; Luke D. Knibbs; Fay H. Johnston
Source:
Environmental pollution 2020 v.256 pp. 113340
ISSN:
0269-7491
Subject:
air pollution; antibiotics; asthma; childhood; children; coal; cosmetics; drug therapy; emissions; health services; infancy; maternal exposure; mine fires; models; parents; particulates; regression analysis; risk; Victoria (Australia)
Abstract:
... Evidence of health effects following early life exposure to short-to-medium duration of high pollution levels is extremely limited.We aimed to evaluate the associations between: 1. intrauterine exposure to fine particulate matter (PM2.5) from coal mine fire emissions and the frequencies of general practitioner attendances and dispensations of prescribed asthma inhalers, steroid skin creams, and an ...
DOI:
10.1016/j.envpol.2019.113340

48. Genomic Regions 10q22.2, 17q21.31, and 2p23.1 Can Contribute to a Lower Lung Function in African Descent Populations

Author:
Héllen Fonseca; Thiago M. da Silva; Mariana Saraiva; Meddly L. Santolalla; Hanaisa P. Sant’Anna; Nathalia M. Araujo; Natália P. Lima; Raimon Rios; Eduardo Tarazona-Santos; Bernardo L Horta; Alvaro Cruz; Mauricio L. Barreto; Camila A. Figueiredo
Source:
Genes 2020 v.11 no.9 pp. -
ISSN:
2073-4425
Subject:
African Americans; Africans; adults; ancestry; asthma; children; computer software; genetic factors; genomics; lung function; phenotype; single nucleotide polymorphism; social change; Brazil; Latin America
Abstract:
... Accumulated evidence supports the contribution of genetic factors in modulating airway function, especially ancestry. We investigated whether genetic polymorphisms can affect lung function in a mixed Brazilian child population using the admixture mapping strategy through RFMix software version 1.5.4 (Stanford University, Stanford, CA, USA), followed by fine mapping, to identify regions whereby loc ...
DOI:
10.3390/genes11091047

49. Geospatial-temporal analysis of the impact of ozone on asthma rescue inhaler use

Author:
Joshua R. Pepper; Meredith A. Barrett; Jason G. Su; Rajan Merchant; Kelly Henderson; David Van Sickle; John R. Balmes
Source:
Environment international 2020 v.136 pp. 105331
ISSN:
0160-4120
Subject:
acute exposure; adults; agonists; air pollutants; air pollution; asthma; children; drug therapy; females; linear models; monitoring; morbidity; ozone; particulates; United States
Abstract:
... Asthma is one of the most common chronic respiratory diseases in the United States. Several outdoor air pollutants have been associated with asthma morbidity. Previous studies of the effects of short-term air pollution exposure have been limited by potential exposure misclassification and limited spatial and temporal resolution of asthma outcome measures.We aimed to assess the association of short ...
DOI:
10.1016/j.envint.2019.105331

50. Home environmental and lifestyle factors associated with asthma, rhinitis and wheeze in children in Beijing, China

Author:
Shaodan Huang; Eric Garshick; Louise B. Weschler; Chuan Hong; Jing Li; Linyan Li; Fang Qu; Dewen Gao; Yanmin Zhou; Jan Sundell; Yinping Zhang; Petros Koutrakis
Source:
Environmental pollution 2020 v.256 pp. 113426
ISSN:
0269-7491
Subject:
Blattodea; air conditioning; algorithms; antibiotics; asthma; children; cooking; cross-sectional studies; industrialization; lifestyle; model validation; occupations; parents; pets; pregnancy; printers; rhinitis; risk factors; rivers; urbanization; winter; China
Abstract:
... The prevalence of asthma and allergic diseases has increased rapidly in urban China since 2000. There has been limited study of associations between home environmental and lifestyle factors with asthma and symptoms of allergic disease in China.In a cross-sectional analysis of 2214 children in Beijing, we applied a two-step hybrid Least Absolute Shrinkage and Selection Operator (LASSO) algorithm to ...
DOI:
10.1016/j.envpol.2019.113426
PubMed:
31672368
PubMed Central:
PMC7050389

51. Impact of asthma on children´s gustatory sensitivity, masticatory and feeding behaviors

Author:
CJ Arias-Guillen; DA Prado; R Tuon; KGO Scudine; MBD Gavião; E Lamy; MCS Marquezin; PM Castelo
Source:
Physiology & behavior 2020 v.223 pp. 112961
ISSN:
0031-9384
Subject:
appetite; asthma; children; hospitals; nutritional status; sucrose; taste sensitivity; therapeutics; urea
Abstract:
... Asthma is a chronic inflammatory disease, in which disturbances in breathing, masticatory and swallowing functions may impact the eating behavior. The aim of the study was to evaluate the impact of asthma on taste sensitivity, masticatory behavior and feeding problems in children. The sample consisted of 91 children (6-7y) divided into two groups: asthma (n=46) and control group (n=45). Interviews ...
DOI:
10.1016/j.physbeh.2020.112961

52. Implementation of various hypothetical low emission zone scenarios in Greater Paris: Assessment of fine-scale reduction in exposure and expected health benefits

Author:
Sabine Host; Cécile Honoré; Fabrice Joly; Adrien Saunal; Alain Le Tertre; Sylvia Medina
Source:
Environmental research 2020 v.185 pp. 109405
ISSN:
0013-9351
Subject:
adults; air pollution; air quality; asthma; children; chronic diseases; decision making; emissions; health effects assessments; issues and policy; models; myocardial ischemia; nitrogen dioxide; particulates; pollution control; socioeconomic status; stakeholders; traffic
Abstract:
... Literature assessing the effects of policies aimed at reducing traffic-related air pollution is scarce. The aims of this study were to evaluate the expected impacts, in terms of air quality and health effects, of various hypothetical low-emission zone (LEZ) scenarios in Greater Paris for a planned intervention in 2018/2019 which combine two different perimeters and two levels of vehicles ban, and ...
DOI:
10.1016/j.envres.2020.109405

53. Inactivated influenza vaccine does not reduce all cause respiratory illness in children with pre-existing medical conditions

Author:
Marieke L.A. de Hoog; Roderick P. Venekamp; Adam Meijer; Elisabeth A.M. Sanders; Patricia C.J.L. Bruijning-Verhagen
Source:
Vaccine 2020 v.38 no.17 pp. 3397-3403
ISSN:
0264-410X
Subject:
Orthomyxoviridae; asthma; cardiovascular diseases; children; databases; diabetes mellitus; equations; guidelines; immunization; influenza; influenza vaccines; models; monitoring; observational studies
Abstract:
... The effectiveness of inactivated influenza vaccine (IIV) immunization in preventing all cause respiratory illness (RI) in children with pre-existing medical conditions has not been fully established and varies from season to season. This study aims to quantify the overall impact of IIV immunization on primary care attended RI episodes in children with pre-existing medical conditions, using robust ...
DOI:
10.1016/j.vaccine.2019.11.086

54. Incidence rates of health outcomes of interest among Chinese children exposed to selected vaccines in Yinzhou Electronic Health Records: A population-based retrospective cohort study

Author:
Kui Huang; Sha Tao; Xiaofeng Zhou; Jingping Mo; Bowen Zhu; Peng Shen; Hongbo Lin; Patrick J. Arena; Na He
Source:
Vaccine 2020 v.38 no.18 pp. 3422-3428
ISSN:
0264-410X
Subject:
Chinese people; Enterovirus C; Guillain-Barre Syndrome; Haemophilus influenzae; anaphylaxis; apnea; asthma; children; cohort studies; community health; databases; experimental design; health services; hospitals; immunization; polysaccharides; seizures; telemedicine; tetanus; urticaria; vaccines; China
Abstract:
... Oral poliovirus vaccine (OPV) and diphtheria-tetanus-acellular pertussis vaccine (DTaP) are widely used in China while Haemophilus influenzae type b vaccines (Hib) and a DTaP, inactivated poliovirus (IPV) andHib polysaccharide conjugated to tetanus protein (PRP ~ T) combined vaccine (DTaP–IPV//PRP ~ T) have lower coverage. There are limited safety data on these vaccines in Chinese pediatric popula ...
DOI:
10.1016/j.vaccine.2020.03.013

55. Influence of residential land cover on childhood allergic and respiratory symptoms and diseases: Evidence from 9 European cohorts

Author:
Eija Parmes; Giancarlo Pesce; Clive E. Sabel; Sandra Baldacci; Roberto Bono; Sonia Brescianini; Cristina D'Ippolito; Wojciech Hanke; Milena Horvat; Hilkka Liedes; Sara Maio; Pierpaolo Marchetti; Alessandro Marcon; Emanuela Medda; Matthieu Molinier; Silvia Panunzi; Juha Pärkkä; Kinga Polańska; Julie Prud'homme; Paolo Ricci; Janja Snoj Tratnik; Giulia Squillacioti; Maria Antonietta Stazi; Cara Nichole Maesano; Isabella Annesi-Maesano
Source:
Environmental research 2020 v.183 pp. 108953
ISSN:
0013-9351
Subject:
allergic rhinitis; asthma; body mass index; childhood; children; coniferous forests; eczema; education; green infrastructure; land cover; regression analysis; residential areas
Abstract:
... Recent research focused on the interaction between land cover and the development of allergic and respiratory disease has provided conflicting results and the underlying mechanisms are not fully understood. In particular, green space, which confers an overall positive impact on general health, may be significantly contributing to adverse respiratory health outcomes. This study evaluates associatio ...
DOI:
10.1016/j.envres.2019.108953

56. Influence of urban forest on traffic air pollution and children respiratory health

Author:
Lucas de Oliveira e Almeida; André Favaro; William Raimundo-Costa; Ana Carolina Borella Marfil Anhê; Deusmaque Carneiro Ferreira; Victoria Blanes-Vidal; Ana Paula Milla dos Santos Senhuk
Source:
Environmental monitoring and assessment 2020 v.192 no.3 pp. 175
ISSN:
0167-6369
Subject:
air pollution; air quality; asthma; childhood; children; ecosystem services; eyes; green infrastructure; monitoring; morbidity; nitrogen dioxide; nose; ozone; particulates; primary pollutants; questionnaires; roads; schools; traffic; urban areas; urban forests
Abstract:
... This study aimed to assess the air quality, the prevalence of child respiratory morbidity, and the association between them, in urban areas where concentrations of pollutants are expected to be below national limits. The monitoring of PM₁₀, NO₂ and O₃ was performed in five schools, during 9 months. Information about respiratory diseases and associated symptoms were collected from each student usin ...
DOI:
10.1007/s10661-020-8142-4

57. Malondialdehyde in Nasal Fluid: A Biomarker for Monitoring Asthma Control in Relation to Air Pollution Exposure

Author:
Linchen He; Xiaoxing Cui; Zhen Li; Yanbo Teng; Karoline K. Barkjohn; Christina Norris; Lin Fang; Lili Lin; Qian Wang; Xiaojian Zhou; Jianguo Hong; Feng Li; Yinping Zhang; James J. Schauer; Marilyn Black; Michael H. Bergin; Junfeng Jim Zhang
Source:
Environmental science & technology 2020 v.54 no.18 pp. 11405-11413
ISSN:
1520-5851
Subject:
air pollution; asthma; biomarkers; childhood; children; inflammation; malondialdehyde; nitric oxide; nose; oxidative stress; ozone; particulates; technology; urine
Abstract:
... Fine particulate matter (PM₂.₅) and ozone (O₃) may exert oxidative damage in the nose, which is hypothesized to be associated with worsened asthma symptoms. This study, hence, is to explore whether an oxidative stress biomarker, malondialdehyde (MDA) in the nasal fluid, has the potential to aid personalized asthma control. In a panel study of 43 asthmatic children, 5–13 years old, each child was m ...
DOI:
10.1021/acs.est.0c02558

58. Neonatal Vitamin D Status and Risk of Asthma in Childhood: Results from the D-Tect Study

Author:
Fanney Thorsteinsdottir; Isabel Cardoso; Amélie Keller; Maria Stougaard; Peder Frederiksen; Arieh Sierra Cohen; Ekaterina Maslova; Ramune Jacobsen; Vibeke Backer; Berit Lilienthal Heitmann
Source:
Nutrients 2020 v.12 no.3 pp. -
ISSN:
2072-6643
Subject:
age; asthma; childhood; children; incidence; lung function; lungs; nutrients; patients; population; pregnancy; prenatal development; risk; risk reduction; vitamin D; vitamin status
Abstract:
... Background: low vitamin D status in pregnancy can influence the offspring’s lung function and contribute to childhood asthma development. The objective of this study was to examine the influence of neonatal vitamin D status on the development of asthma among children age 3–9 years in a large population sample. Method: in a case-cohort study utilizing a Danish biobank and register data we examined ...
DOI:
10.3390/nu12030842

59. Noise exposure and childhood asthma up to adolescence

Author:
Alva Enoksson Wallas; Charlotta Eriksson; Mikael Ögren; Andrei Pyko; Mattias Sjöström; Erik Melén; Göran Pershagen; Olena Gruzieva
Source:
Environmental research 2020 v.185 pp. 109404
ISSN:
0013-9351
Subject:
adolescence; asthma; childhood; children; infancy; longitudinal studies; noise pollution; pregnancy; psychological stress; questionnaires; regression analysis; time-weighted average; traffic
Abstract:
... Increasing evidence indicates aggravation of immune-mediated diseases due to physiological and psychological stress. Noise is a stressor, however, little is known about its effects on children's respiratory health. This study investigates the association between pre- or postnatal road traffic or occupational noise exposure and asthma as well as related symptoms from infancy to adolescence.The stud ...
DOI:
10.1016/j.envres.2020.109404

60. Perfluoroalkyl substances, airways infections, allergy and asthma related health outcomes – implications of gender, exposure period and study design

Author:
H.E. Kvalem; U.C. Nygaard; K.C. Lødrup Carlsen; K.H. Carlsen; L.S. Haug; B. Granum
Source:
Environment international 2020 v.134 pp. 105259
ISSN:
0160-4120
Subject:
asthma; atopic dermatitis; blood serum; boys; childhood; children; common cold; cross-sectional studies; experimental design; exposure duration; gender; girls; immunosuppression; lung function; perfluorohexane sulfonic acid; perfluorooctane sulfonic acid; perfluorooctanoic acid; puberty; regression analysis; rhinitis; risk; risk reduction; sulfonates
Abstract:
... Exposure to perfluoroalkyl substances (PFASs) has been inconsistently associated with asthma, allergic diseases and airways infections in early childhood. The aim of the study was, therefore, to investigate the effect of childhood exposure to PFASs on asthma and allergy related outcomes and on airways infections before and during puberty using the prospective birth cohort Environment and Childhood ...
DOI:
10.1016/j.envint.2019.105259

61. Prenatal phthalate, paraben, and phenol exposure and childhood allergic and respiratory outcomes: Evaluating exposure to chemical mixtures

Author:
Kimberly Berger; Eric Coker; Stephen Rauch; Brenda Eskenazi; John Balmes; Katie Kogut; Nina Holland; Antonia M. Calafat; Kim Harley
Source:
Science of the total environment 2020 v.725 pp. 138418
ISSN:
0048-9697
Subject:
2,4-dichlorophenol; Bayesian theory; additive effect; asthma; biomarkers; bisphenol A; childhood; children; lung function; metabolites; models; mothers; personal care products; phenol; phthalates; plastics; pregnancy; probability; regression analysis; standard deviation; women
Abstract:
... Chemicals found in personal care products and plastics have been associated with asthma, allergies, and lung function, but methods to address real life exposure to mixtures of these chemicals have not been applied to these associations.We quantified urinary concentrations of eleven phthalate metabolites, four parabens, and five other phenols in mothers twice during pregnancy and assessed probable ...
DOI:
10.1016/j.scitotenv.2020.138418

62. Prevention of New Respiratory Episodes in Children with Recurrent Respiratory Infections: An Expert Consensus Statement from the World Association of Infectious Diseases and Immunological Disorders (WAidid)

Author:
Susanna Esposito; Marcus Herbert Jones; Wojciech Feleszko; José A. Ortega Martell; Oana Falup-Pecurariu; Natalia Geppe; Federico Martinón-Torres; Kun-Ling Shen; Michael Roth; Nicola Principi
Source:
Microorganisms 2020 v.8 no.11 pp. -
ISSN:
2076-2607
Subject:
asthma; bacteria; children; clinical trials; dosage; environmental factors; frequency; hand washing; infants; infection; infectious diseases; knowledge; paper; probiotics; vaccination; vitamin D
Abstract:
... In healthy infants and young children, the development of respiratory tract infections (RTIs) is extremely common. In this paper, we present an international consensus of the available approaches for the prevention of recurrent RTIs in children, including the atopic/allergic ones as well as those with asthma. Few convincing measures for reducing the frequency and clinical relevance of recurrent re ...
DOI:
10.3390/microorganisms8111810

63. Relative impact of meteorological factors and air pollutants on childhood allergic diseases in Shanghai, China

Author:
Yabin Hu; Zhiwei Xu; Fan Jiang; Shenghui Li; Shijian Liu; Meiqin Wu; Chonghuai Yan; Jianguo Tan; Guangjun Yu; Yi Hu; Yong Yin; Shilu Tong
Source:
Science of the total environment 2020 v.706 pp. 135975
ISSN:
0048-9697
Subject:
air; air pollutants; air pollution; allergic rhinitis; asthma; atmospheric pressure; atopic dermatitis; child health; childhood; children; confidence interval; environmental exposure; environmental factors; environmental protection; hospitals; linear models; meteorological data; nitrogen dioxide; nonlinear models; ozone; particulates; relative humidity; solar radiation; sulfur dioxide; temperature; wind speed; China
Abstract:
... Non-optimal weather conditions and air pollution pose a significant threat to children's health. However, the relative impact of different environmental exposures on childhood allergic diseases remains unclear.This study aimed to quantify the relative impact of meteorological factors and air pollutants on childhood allergic diseases in Shanghai, China.Data on clinical visits due to childhood asthm ...
DOI:
10.1016/j.scitotenv.2019.135975

64. Residential green space and medication sales for childhood asthma: A longitudinal ecological study in Belgium

Author:
Raf Aerts; Sebastien Dujardin; Benoit Nemery; An Van Nieuwenhuyse; Jos Van Orshoven; Jean-Marie Aerts; Ben Somers; Marijke Hendrickx; Nicolas Bruffaerts; Mariska Bauwelinck; Lidia Casas; Claire Demoury; Michelle Plusquin; Tim S. Nawrot
Source:
Environmental research 2020 v.189 pp. 109914
ISSN:
0013-9351
Subject:
air pollution; asthma; biodiversity; childhood; children; drug therapy; ecological studies; ecological value; forests; gardens; grasses; grasslands; green infrastructure; pollen; research; Belgium
Abstract:
... Living in green environments has been associated with various health benefits, but the evidence for positive effects on respiratory health in children is ambiguous.To investigate if residential exposure to different types of green space is associated with childhood asthma prevalence in Belgium.Asthma prevalence was estimated from sales data of reimbursed medication for obstructive airway disease ( ...
DOI:
10.1016/j.envres.2020.109914

65. Rhinovirus Infection in Children with Acute Bronchiolitis and Its Impact on Recurrent Wheezing and Asthma Development

Author:
Carlotta Biagi; Alessandro Rocca; Giulia Poletti; Marianna Fabi; Marcello Lanari
Source:
Microorganisms 2020 v.8 no.10 pp. -
ISSN:
2076-2607
Subject:
Enterovirus; Respiratory syncytial virus; asthma; bronchiolitis; children; complications (disease); disease course; frequency; genetic variation; infants; mixed infection; pathogens; population; risk; viruses
Abstract:
... Acute bronchiolitis represents the leading cause of hospitalization in infants. Together with a respiratory syncytial virus, rhinovirus (RV) is one of the most common pathogens associated with bronchiolitis, and its genetic diversity (>150 types) makes the recurrence of RV infections each year quite typical. The frequency of RV infection and co-infection with other viruses and its impact on the cl ...
DOI:
10.3390/microorganisms8101620

66. Role of Respiratory Syncytial Virus in Pediatric Pneumonia

Author:
Sonia Bianchini; Ettore Silvestri; Alberto Argentiero; Valentina Fainardi; Giovanna Pisi; Susanna Esposito
Source:
Microorganisms 2020 v.8 no.12 pp. -
ISSN:
2076-2607
Subject:
Respiratory syncytial virus; accuracy; adulthood; asthma; bronchiolitis; childhood; children; infant mortality; infants; infection; knowledge; microorganisms; oxygen; pathogens; pneumonia; polymerase chain reaction; population; signs and symptoms (animals and humans); technology; therapeutics; vaccines
Abstract:
... Respiratory viral infections represent the leading cause of hospitalization in infants and young children worldwide and the second leading cause of infant mortality. Among these, Respiratory Syncytial Virus (RSV) represents the main cause of lower respiratory tract infections (LRTIs) in young children worldwide. RSV manifestation can range widely from mild upper respiratory infections to severe re ...
DOI:
10.3390/microorganisms8122048

67. Sex Difference Between Trace Elements and Pulmonary Functions in Children

Author:
Zhenzhen Pan; Xiaojuan Zhang; Yu Hui; Hongxia Xiang; Qian Wang; Shiyao Xu; Ling Li
Source:
Biological trace element research 2020 v.197 no.2 pp. 405-410
ISSN:
0163-4984
Subject:
asthma; atomic absorption spectrometry; blood sampling; blood serum; boys; children; cross-sectional studies; girls; immunoglobulin E; lung function; magnesium; nutrient deficiencies; regression analysis; screening; selenium; zinc; China
Abstract:
... It has been defined that deficiency of trace elements plays an important role in the progression of asthma. However, the relationship between blood zinc (Zn), selenium (Se), and magnesium (Mg) and pulmonary functions in children remains to be clarified. A cross-sectional study was conducted in Wuxi, China, and a total of 202 healthy children were recruited. The forced vital capacity volume (FVC) a ...
DOI:
10.1007/s12011-019-02019-4

68. Sufficient vitamin D status positively modified ventilatory function in asthmatic children following a Mediterranean diet enriched with fatty fish intervention study

Author:
Maria M. Papamichael; Catherine Itsiopoulos; Katrina Lambert; Charis Katsardis; Dimitris Tsoukalas; Bircan Erbas
Source:
Nutrition research 2020 v.82 pp. 99-109
ISSN:
0271-5317
Subject:
Mediterranean diet; asthma; blood serum; clinical trials; enzyme-linked immunosorbent assay; fatty fish; fish consumption; lung function; nitric oxide; nutrition research; nutritional intervention; public health
Abstract:
... Asthma in children is the most prevalent allergic disease worldwide that has become a major public health priority. The objective of this study was to examine the relationship between baseline serum vitamin D status, spirometry, and fractional exhaled nitric oxide levels (FeNO) in 64 Greek children with ‘mild asthma’ aged 5 to 12 years (51.6% male) in a dietary intervention study. We hypothesized ...
DOI:
10.1016/j.nutres.2020.08.004

69. Towards a fuller assessment of the economic benefits of reducing air pollution from fossil fuel combustion: Per-case monetary estimates for children's health outcomes

Author:
E. Shea; F. Perera; D. Mills
Source:
Environmental research 2020 v.182 pp. 109019
ISSN:
0013-9351
Subject:
adulthood; air pollution; air quality; asthma; autism; child health; childhood; children; climate change; cost estimates; cost of illness analysis; decision making; economic costs; environmental exposure; environmental policy; financial economics; fossil fuels; fuel combustion; low birth weight; pollution control; premature birth; systematic review; United Kingdom; United States
Abstract:
... Impacts on children's health are under-represented in benefits assessments of policies related to ambient air quality and climate change. To complement our previous compilation of concentration-response (C-R) functions for a number of children's health outcomes associated with air pollution, we provide per-case monetary estimates of the same health outcomes.Our goal was to establish per-case monet ...
DOI:
10.1016/j.envres.2019.109019
PubMed:
31838408
PubMed Central:
PMC7024643

70. A combined cohort analysis of prenatal exposure to phthalate mixtures and childhood asthma

Author:
Margaret A. Adgent; Kecia N. Carroll; Marnie F. Hazlehurst; Christine T. Loftus; Adam A. Szpiro; Catherine J. Karr; Emily S. Barrett; Kaja Z. LeWinn; Nicole R. Bush; Frances A. Tylavsky; Kurunthachalam Kannan; Sheela Sathyanarayana
Source:
Environment international 2020 v.143 pp. 105970
ISSN:
0160-4120
Subject:
asthma; childhood; children; confidence interval; drug therapy; environment; maternal exposure; metabolites; odds ratio; phthalates; regression analysis; urine
Abstract:
... Previous studies of prenatal phthalate exposure and childhood asthma are inconsistent. These studies typically model phthalates as individual, rather than co-occurring, exposures. We investigated whether prenatal phthalates are associated with childhood wheeze and asthma using a mixtures approach.We studied dyads from two prenatal cohorts in the ECHO-PATHWAYS consortium: CANDLE, recruited 2006–201 ...
DOI:
10.1016/j.envint.2020.105970

71. The impact of household air cleaners on the oxidative potential of PM2.5 and the role of metals and sources associated with indoor and outdoor exposure

Author:
Collin Brehmer; Christina Norris; Karoline K. Barkjohn; Mike H. Bergin; Junfeng Zhang; Xiaoxing Cui; Yanbo Teng; Yinping Zhang; Marilyn Black; Zhen Li; Martin M. Shafer; James J. Schauer
Source:
Environmental research 2020 v.181 pp. 108919
ISSN:
0013-9351
Subject:
aerosols; air cleaners; air quality; asthma; children; emissions; filters; filtration; health effects assessments; human health; humans; macrophages; mass spectrometry; metals; models; particulates; reactive oxygen species; regression analysis; roads; China
Abstract:
... The health effects associated with human exposure to airborne fine particulate matter (PM₂.₅) have been linked to the ability of PM₂.₅ to facilitate the production of excess cellular reactive oxygen species (oxidative potential). Concern about the adverse human health impacts of PM₂.₅ has led to the increased use of indoor air cleaners to improve indoor air quality, which can be an important envir ...
DOI:
10.1016/j.envres.2019.108919

72. Air pollution and respiratory hospital admissions in Shiraz, Iran, 2009 to 2015

Author:
Zahra Soleimani; Ali Darvishi Boloorani; Reza Khalifeh; Pari Teymouri; Alireza Mesdaghinia; Dale W. Griffin
Source:
Atmospheric environment 2019 v.209 pp. 233-239
ISSN:
1352-2310
Subject:
acute exposure; air pollutants; air pollution; asthma; atmospheric chemistry; carbon monoxide; children; cities; demographic statistics; hospitals; linear models; nitrogen dioxide; ozone; particulates; patients; pneumonia; principal component analysis; relative humidity; relative risk; sulfur dioxide; temperature; urban areas; Iran
Abstract:
... Air pollution has been identified as one of the most challenging health issues in urban areas worldwide.The aim of this study was to investigate the association between short-term exposure to ambient air pollution and respiratory disease over a long-term period in Shiraz, one of the largest cities in Iran. Methods: hospital admissions due to respiratory diseases (asthma, pneumonia, chronic obstruc ...
DOI:
10.1016/j.atmosenv.2019.04.030

73. Association of urinary bisphenols and triclosan with thyroid function during early pregnancy

Author:
Arash Derakhshan; Huan Shu; Robin P. Peeters; Andreas Kortenkamp; Christian H. Lindh; Barbara Demeneix; Carl-Gustaf Bornehag; Tim I.M. Korevaar
Source:
Environment international 2019 pp. -
ISSN:
0160-4120
Subject:
bisphenol F; bisphenol A; blood serum; bisphenol S; humans; triclosan; uncertainty; thyrotropin; triiodothyronine; pregnancy; children; asthma; gestational age; thyroid function; enzyme activity
Abstract:
... Bisphenols and triclosan are considered as potential thyroid disruptors. While mild alterations in maternal thyroid function can result in adverse pregnancy and child developmental outcomes, there is still uncertainty whether bisphenols can interfere with thyroid function during pregnancy.We aimed to investigate the association of urinary bisphenol A (BPA), bisphenol S (BPS), bisphenol F (BPF) and ...
DOI:
10.1016/j.envint.2019.105123

74. Associations of Food Allergy and Other Allergic Conditions with Attention Deficit/Hyperactivity Disorder in US Children (P16-032-19)

Author:
Guifeng Xu; Buyun Liu; Wei Bao
Source:
Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
ISSN:
2475-2991
Subject:
asthma; children; confidence interval; data analysis; dermatitis; educational status; food allergies; household income; nationalities and ethnic groups; odds ratio; questionnaires; regression analysis; rhinitis; surveys; United States
Abstract:
... Association between allergic conditions and attention deficit/hyperactivity disorder (ADHD) is still debated. Although there are several studies confirmed associations between ADHD and allergic rhinitis and asthma, little is known about the association between food allergy and ADHD. We examined the association of food allergy and other allergic conditions with ADHD in US children. We analyzed data ...
DOI:
10.1093/cdn/nzz050.P16-032-19

75. Associations of air pollution, obesity and cardiometabolic health in young adults: The Meta-AIR study

Author:
Jeniffer S. Kim; Zhanghua Chen; Tanya L. Alderete; Claudia Toledo-Corral; Fred Lurmann; Kiros Berhane; Frank D. Gilliland
Source:
Environment international 2019 pp. -
ISSN:
0160-4120
Subject:
abdominal fat; adiposity; aerodynamics; air pollutants; air pollution; asthma; blood lipids; body mass index; child health; childhood; children; fasting; glucose; high density lipoprotein cholesterol; insulin; lipid composition; lipid metabolism; low density lipoprotein cholesterol; models; nitrogen dioxide; obesity; ozone; particulates; regression analysis; risk; roads; standard deviation; total nitrogen; triacylglycerols; very low density lipoprotein; young adults
Abstract:
... Growing evidence indicates exposure to air pollution contributes to obesity and cardiometabolic disease risk in children and adults, however studies are lacking in young adulthood, an important transitional period in the life course. The aim of this study was to examine the associations of short- and long-term regional ambient and near-roadway air pollution (NRAP) exposures on adiposity and cardio ...
DOI:
10.1016/j.envint.2019.105180
PubMed:
31622905
PubMed Central:
PMC6884139

76. Associations of wildfire smoke PM2.5 exposure with cardiorespiratory events in Colorado 2011–2014

Author:
Jennifer D. Stowell; Guannan Geng; Eri Saikawa; Howard H. Chang; Joshua Fu; Cheng-En Yang; Qingzhao Zhu; Yang Liu; Matthew J. Strickland
Source:
Environment international 2019 pp. -
ISSN:
0160-4120
Subject:
adults; aerodynamics; asthma; bronchitis; cardiovascular diseases; chemical composition; children; climate change; epidemiological studies; exposure models; particulates; regression analysis; smoke; spatial data; wildfires; Colorado
Abstract:
... Substantial increases in wildfire activity have been recorded in recent decades. Wildfires influence the chemical composition and concentration of particulate matter ≤2.5 μm in aerodynamic diameter (PM2.5). However, relatively few epidemiologic studies focus on the health impacts of wildfire smoke PM2.5 compared with the number of studies focusing on total PM2.5 exposure.We estimated the associati ...
DOI:
10.1016/j.envint.2019.105151

77. Astragalus membranaceus improves therapeutic efficacy of asthmatic children by regulating the balance of Treg/Th17 cells

Author:
Wei WANG; Qing-Bin LIU; Wei JING
Source:
Chinese journal of natural medicines 2019 v.17 no.4 pp. 252-263
ISSN:
1875-5364
Subject:
Astragalus membranaceus; Oriental traditional medicine; asthma; blood serum; childhood; children; density gradient centrifugation; flow cytometry; formononetin; genistein; high performance liquid chromatography; immunoglobulin E; interleukin-17; interleukin-23; isoquercitrin; isorhamnetin; kaempferol; lung function; mononuclear leukocytes; quercetin; remission; swine; therapeutics; transforming growth factor beta
Abstract:
... Astragalus membranaceus may be a potential therapy for childhood asthma but its driving mechanism remains elusive. The main components of A. membranaceus were identified by HPLC. The children with asthma remission were divided into two combination group (control group, the combination of budesonide and terbutaline) and A. membranaceus group (treatment group, the combination of budesonide, terbutal ...
DOI:
10.1016/S1875-5364(19)30029-9

78. Benzo[a]pyrene is associated with dysregulated myelo-lymphoid hematopoiesis in asthmatic children

Author:
Hyunok Choi; Won-min Song; Minghui Wang; Radim J. Sram; Bin Zhang
Source:
Environment international 2019 v.128 pp. 218-232
ISSN:
0160-4120
Subject:
CD8-positive T-lymphocytes; DNA methylation; GATA transcription factors; artificial intelligence; asthma; benzo(a)pyrene; biosynthesis; childhood; children; data analysis; epigenetics; gene expression; glutathione transferase; hematopoiesis; heme; inflammation; regulator genes; stem cells; transcription (genetics); transcription factor NF-kappa B; umbilical cord; urban areas; urban population; Czech Republic
Abstract:
... The extent to which ambient benzo[a]pyrene (B[a]P) contributes to mechanistically distinct de novo asthma remains unknown.To identify molecular signatures and regulatory networks underlying childhood exposure to ambient B[a]P and asthma, using robust and unbiased systems biology approaches.Clinically confirmed asthmatic (n = 191) vs. control (n = 194) children (aged, 7–15) were enrolled from a pol ...
DOI:
10.1016/j.envint.2019.04.052

79. Breastfeeding and Its Relationship to Childhood Respiratory Allergies and Allergic Asthma a Longitudinal Study (P11-104-19)

Author:
Galya Bigman
Source:
Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
ISSN:
2475-2991
Subject:
asthma; breast feeding; childhood; children; complementary foods; hypersensitivity; infant feeding; longitudinal studies; mothers; questionnaires; risk reduction; siblings; smoking (habit)
Abstract:
... Breastfeeding might be associated with respiratory allergy and asthma subtypes(i.e., allergic asthma), but such relations have never been examined yet in the US. Therefore, the aims of the study were: To examined the association between breastfeeding and respiratory allergy in children aged six years. To examined the association between breastfeeding and asthma including asthma subtypes (allergic) ...
DOI:
10.1093/cdn/nzz048.P11-104-19

80. Children environmental exposure to particulate matter and polycyclic aromatic hydrocarbons and biomonitoring in school environments: A review on indoor and outdoor exposure levels, major sources and health impacts

Author:
Marta Oliveira; Klara Slezakova; Cristina Delerue-Matos; Maria Carmo Pereira; Simone Morais
Source:
Environment international 2019 v.124 pp. 180-204
ISSN:
0160-4120
Subject:
schools; guidelines; skin diseases; rural areas; metabolites; risk; biomarkers; air; environmental exposure; air quality; children; particulates; asthma; Asians; child health; polycyclic aromatic hydrocarbons; benzo(a)pyrene; environmental monitoring; Pacific Ocean Islands; Africa
Abstract:
... Children, an important vulnerable group, spend most of their time at schools (up to 10 h per day, mostly indoors) and the respective air quality may significantly impact on children health. Thus, this work reviews the published studies on children biomonitoring and environmental exposure to particulate matter (PM) and polycyclic aromatic hydrocarbons (PAHs) at school microenvironments (indoors and ...
DOI:
10.1016/j.envint.2018.12.052

81. Classroom indoor PM2.5 sources and exposures in inner-city schools

Author:
Aleshka Carrion-Matta; Choong-Min Kang; Jonathan M. Gaffin; Marissa Hauptman; Wanda Phipatanakul; Petros Koutrakis; Diane R. Gold
Source:
Environment international 2019 v.131 pp. 104968
ISSN:
0160-4120
Subject:
aerosols; asthma; autumn; biomass burning; calcium; children; dust; environmental exposure; models; monitoring; morbidity; particulates; pollution; schools; soil; spring; sulfur; vehicles (equipment); winter; Northeastern United States
Abstract:
... Children spend over 6 h a day in schools and have higher asthma morbidity from school environmental exposures. The present study aims to determine indoor and outdoor possible sources affecting indoor PM2.5 in classrooms. Weeklong indoor PM2.5 samples were collected from 32 inner-city schools from a Northeastern U.S. community during three seasons (fall, winter and spring) during the years 2009 to ...
DOI:
10.1016/j.envint.2019.104968
PubMed:
31295642
PubMed Central:
PMC6728184

82. Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial

Author:
Gabriel Manarin; Daniela Anderson; Jorgete Maria e Silva; Juliana da Silva Coppede; Persio Roxo-Junior; Ana Maria Soares Pereira; Fabio Carmona
Source:
Journal of ethnopharmacology 2019 v.238 pp. 111882
ISSN:
0378-8741
Subject:
Curcuma longa; adolescents; anti-inflammatory activity; asthma; beta-adrenergic agonists; children; clinical trials; disease control; lung function; patients; placebos; roots; traditional medicine
Abstract:
... Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment.We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, wil ...
DOI:
10.1016/j.jep.2019.111882

83. Cytokine production in allergic and Trichuris trichiura-infected children from an urban region of the Brazilian northeast

Author:
Juliana P. Gonçales; Cassia G.O. Nobrega; Wheverton R.C. Nascimento; Virginia M.B. Lorena; Décio M. Peixoto; Vlaudia M.A. Costa; Constança S. Barbosa; Dirceu Solé; Emanuel S.C. Sarinho; Valdênia M.O. Souza
Source:
Parasitology international 2019 pp. 101918
ISSN:
1383-5769
Subject:
Trichuris trichiura; asthma; blood sampling; cell-mediated immunity; children; helminths; interferon-gamma; interleukin-10; interleukin-17; interleukin-4; interleukin-6; mitogens; questionnaires; tumor necrosis factor-alpha; urban areas
Abstract:
... The relationship between the cellular immune response during Trichuris trichiura infection and asthma has not yet been established. In this study, the cytokines interleukin (IL)-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ and IL-17A were evaluated in asthmatic children harboring T. trichiura. For this assessment, asthmatic and non-asthmatic children (ISAAC questionnaire) were submitted to parasitological t ...
DOI:
10.1016/j.parint.2019.04.015

84. Dependence modeling for recurrent event times subject to right‐censoring with D‐vine copulas

Author:
Nicole Barthel; Candida Geerdens; Claudia Czado; Paul Janssen
Source:
Biometrics 2019 v.75 no.2 pp. 439-451
ISSN:
0006-341X
Subject:
asthma; biometry; children; models; probability distribution
Abstract:
... In many time‐to‐event studies, the event of interest is recurrent. Here, the data for each sample unit correspond to a series of gap times between the subsequent events. Given a limited follow‐up period, the last gap time might be right‐censored. In contrast to classical analysis, gap times and censoring times cannot be assumed independent, i.e., the sequential nature of the data induces dependent ...
DOI:
10.1111/biom.13014

85. Diesel exhausts particles: Their role in increasing the incidence of asthma. Reviewing the evidence of a causal link

Author:
X. Muñoz; E. Barreiro; V. Bustamante; J.L. Lopez-Campos; F.J. González-Barcala; M.J. Cruz
Source:
Science of the total environment 2019 v.652 pp. 1129-1138
ISSN:
0048-9697
Subject:
Toll-like receptors; adults; air pollutants; air pollution; antigens; asthma; children; cytokines; epigenetics; epithelium; inflammation; microbiome; oxidative stress
Abstract:
... Exposure to air pollutants has been correlated with an increase in the severity of asthma and in the exacerbation of pre-existing asthma. However, whether or not environmental pollution can cause asthma remains a controversial issue. The present review analyzes the current scientific evidence of the possible causal link between diesel exhaust particles (DEP), the solid fraction of the complex mixt ...
DOI:
10.1016/j.scitotenv.2018.10.188

86. Dietary Acid Load: A Novel Nutritional Target in Overweight/Obese Children with Asthma?

Author:
Pedro Cunha; Inês Paciência; João Cavaleiro Rufo; Francisca Castro Mendes; Mariana Farraia; Renata Barros; Diana Silva; Luís Delgado; Patrícia Padrão; André Moreira; Pedro Moreira
Source:
Nutrients 2019 v.11 no.9 pp. -
ISSN:
2072-6643
Subject:
asthma; body mass index; childhood obesity; children; cough; diet recall; dyspnea; educational status; energy intake; enzymes; equations; females; inflammation; lung function; lungs; nutrients; odds ratio; pH; phenotype; physical activity
Abstract:
... Obesity has been repeatedly linked to asthma, and several potential mechanisms have been proposed in the etiologies of the obese-asthma phenotype. Considering that lungs play an important role in systemic pH and acid–base regulation, are a key organ in asthma development, and that nutritional inadequacy of several nutrients and high dietary acid load can affect airway inflammation and reacti ...
DOI:
10.3390/nu11092255
PubMed:
31546888
PubMed Central:
PMC6770083

87. Dietary intake of fish and ω-3 polyunsaturated fatty acids and physician-diagnosed allergy in Japanese population: The Japan Environment and Children's Study

Author:
Kei Hamazaki; Akiko Tsuchida; Ayako Takamori; Tomomi Tanaka; Mika Ito; Hidekuni Inadera; Japan Environment and Children's Study (JECS) Group
Source:
Nutrition 2019 v.61 pp. 194-201
ISSN:
0899-9007
Subject:
asthma; atopic dermatitis; children; clinical trials; conjunctivitis; epidemiological studies; females; fish; fish consumption; hay fever; males; nutrition risk assessment; observational studies; omega-3 fatty acids; polyunsaturated fatty acids; pregnant women; questionnaires; regression analysis; therapeutics; Japan
Abstract:
... Emerging evidence from epidemiologic studies and clinical trials indicates that ω-3 polyunsaturated fatty acids (PUFAs) may have a preventive or therapeutic effect on allergy, although the results remain controversial. The aim of this study was to investigate the association between intake of fish and ω-3 PUFAs with risk for lifetime prevalence of physician-diagnosed allergy in a Japanese populati ...
DOI:
10.1016/j.nut.2018.11.010

88. Different sensitivities to ambient temperature between first- and re-admission childhood asthma cases in Hong Kong – A time series study

Author:
Holly Ching Yu Lam; Shakoor Hajat; Emily Ying Yang Chan; William Bernard Goggins
Source:
Environmental research 2019 v.170 pp. 487-492
ISSN:
0013-9351
Subject:
air pollutants; air pollution; ambient temperature; asthma; childhood; children; cold; cold season; disease control; hospitals; meteorological parameters; nonlinear models; risk; seasonal variation; summer; time series analysis; winter; China
Abstract:
... Asthma can be triggered by various factors due to different etiologies. Environmental factors remain a common trigger of asthma, especially amongst children, and such ambient exposures can be harder to avoid compared to behavioral triggers. As such, the contribution of environmental factors may be enhanced when considering repeat asthma cases compared to initial presentations. To test this hypothe ...
DOI:
10.1016/j.envres.2018.12.002

89. Does breast milk adiponectin affect BMI and cardio-metabolic markers in childhood?

Author:
Lenie van Rossem; Henriette A. Smit; Eef G. W. M. Lentjes; Inge Maitimu-Smeele; Bert Brunekreef; Gerard H. Koppelman; Alet H. Wijga
Source:
British journal of nutrition 2019 v.121 no.8 pp. 905-913
ISSN:
1475-2662
Subject:
adiponectin; blood pressure; siblings; adults; breast feeding; glucose; observational studies; blood serum; models; mites; pregnancy; children; asthma; childhood; lipid metabolism; body mass index; weight gain; long term effects; cholesterol; breast milk; birth weight
Abstract:
... Observational studies suggest that breast-feeding is associated with a more favourable BMI and cardio-metabolic markers, but potential underlying mechanisms are unclear. As serum adiponectin has an important function in adults for glucose and lipid metabolism, we assessed 251 participants of the Prevention and Incidence of Asthma and Mite Allergy birth cohort whether breast milk adiponectin is ass ...
DOI:
10.1017/S0007114519000266
PubMed:
30728088 30728088

90. Early-life exposure to household chemicals and wheezing in children

Author:
Ondřej Mikeš; Markéta Vrbová; Jana Klánová; Pavel Čupr; Jan Švancara; Hynek Pikhart
Source:
Science of the total environment 2019 v.663 pp. 418-425
ISSN:
0048-9697
Subject:
asthma; childhood; children; environmental factors; epidemiological studies; longitudinal studies; models; odds ratio; pathogens; phenotype; pregnancy; regression analysis; risk
Abstract:
... The prevalence of the asthmatic symptoms among children increases globally over the time. Reduced exposure to pathogens in early childhood and increased exposure to anthropogenic irritants result in increased risk of wheezing in children, and all of this may be related to the usage of household chemicals. Objective of this analysis thus was to study the potential effects of overall exposure to hom ...
DOI:
10.1016/j.scitotenv.2019.01.254

91. Effect of Adherence to Mediterranean Diet during Pregnancy on Children’s Health: A Systematic Review

Author:
Carlotta Biagi; Mattia Di Nunzio; Alessandra Bordoni; Davide Gori; Marcello Lanari
Source:
Nutrients 2019 v.11 no.5 pp. -
ISSN:
2072-6643
Subject:
public health; body weight; premature birth; systematic review; environmental factors; children; healthy eating habits; asthma; maternal nutrition; pregnancy; neural tube defects; Mediterranean diet; adults; protective effect
Abstract:
... The traditional Mediterranean diet has been shown to be a healthy eating pattern that protects against the development of many diseases in adults and children. Pregnancy is a critical period of plasticity during which foetal development may be significantly influenced by different environmental factors, including maternal nutrition. In this context, several studies have examined the potential bene ...
DOI:
10.3390/nu11050997
PubMed:
31052443
PubMed Central:
PMC6566280

92. Effects of childhood exposure to PM2.5 in a Memphis pediatric asthma cohort

Author:
Tonny J. Oyana; Pradeep Podila; George E. Relyea
Source:
Environmental monitoring and assessment 2019 v.191 no.Supplement 2 pp. 330
ISSN:
0167-6369
Subject:
air pollution; asthma; burden of disease; childhood; children; confidence interval; data collection; emissions; health services; hospitals; insurance; odds ratio; particulates; patients; regression analysis; risk
Abstract:
... The effects of childhood exposure to ambient air pollution and their influences on healthcare utilization and respiratory outcomes in Memphis pediatric asthma cohort are still unknown. This study seeks to (1) investigate individual-level associations between asthma and exposure measures in high asthma rate and low asthma rate areas and (2) determine factors that influence asthma at first year of a ...
DOI:
10.1007/s10661-019-7419-y

93. Effects of epigallocatechin-3-gallate on the HMGB1/RAGE pathway in PM2.5-exposed asthmatic rats

Author:
YuanZhe Li; LiXia Chen; FeiFei Guo; Yang Cao; Wenjie Hu; Yang Shi; XinChun Lin; Jie Hou; LiPing Li; XianFei Ding; YanJun Guo
Source:
Biochemical and biophysical research communications 2019 v.513 no.4 pp. 898-903
ISSN:
0006-291X
Subject:
animal models; antioxidants; asthma; children; chronic exposure; epigallocatechin gallate; immunomodulators; inflammation; lungs; messenger RNA; nucleoproteins; particulates; pathogenesis; protective effect; protein content; protein synthesis; rats; signal transduction; smooth muscle
Abstract:
... Current studies have shown that long-term exposure to fine particulate matter (PM2.5) can aggravate lung injury in asthmatic children. The HMGB1/RAGE pathway may play an important role, but few studies on the HMGB1/RAGE signaling pathway in PM2.5-induced asthma have been performed. Epigallocatechin-3-gallate (EGCG), which has antioxidant, anti-inflammatory and immunomodulatory effects, has not bee ...
DOI:
10.1016/j.bbrc.2019.03.165

94. Efficacy of a Mediterranean diet supplemented with fatty fish in ameliorating inflammation in paediatric asthma: a randomised controlled trial

Author:
M. M. Papamichael; Ch. Katsardis; K. Lambert; D. Tsoukalas; M. Koutsilieris; B. Erbas; C. Itsiopoulos
Source:
Journal of human nutrition and dietetics 2019 v.32 no.2 pp. 185-197
ISSN:
0952-3871
Subject:
Mediterranean diet; asthma; body mass index; childhood; children; confidence interval; fatty fish; females; fish consumption; fish meal; immunomodulators; inflammation; lung function; males; morbidity; nitric oxide; omega-3 fatty acids; physical activity; quality of life; randomized clinical trials
Abstract:
... BACKGROUND: Childhood asthma is the most common respiratory disorder worldwide, being associated with increased morbidity and a decreased quality of life. Omega‐3 fatty acids have anti‐inflammatory and immunomodulating properties; however, their efficacy in asthma is controversial. The present study aimed to examine the efficacy of a Mediterranean diet supplemented with a high omega‐3 ‘fatty’ fish ...
DOI:
10.1111/jhn.12609

95. Excess of children’s outpatient consultations due to asthma and bronchitis and the association between meteorological variables in Canoas City, Southern Brazil

Author:
Igor Rojahn da Silva; Anderson Spohr Nedel; Júlio Renato Quevedo Marques; Luciano Ritter Nolasco Júnior
Source:
International journal of biometeorology 2019 v.63 no.11 pp. 1517-1524
ISSN:
0020-7128
Subject:
air; asthma; atmospheric pressure; bioclimatology; bronchitis; children; cold; humans; meteorological data; relative humidity; sensation; temperature; wind speed; Brazil
Abstract:
... The southern Brazilian city of Canoas, situated in the metropolitan region of Porto Alegre, is subject to several annual meteorological phenomena, such as cold fronts and squall lines. Here, we assess the relationship between meteorological conditions and outpatient consultations for asthma or bronchitis in children from Canoas City. Data from outpatient consultations of children (below 9 years), ...
DOI:
10.1007/s00484-018-1650-z

96. Exposure to Vitamin D Fortification Policy in Prenatal Life and the Risk of Childhood Asthma: Results from the D-Tect Study

Author:
Fanney Thorsteinsdottir; Ekaterina Maslova; Ramune Jacobsen; Peder Frederiksen; Amélie Keller; Vibeke Backer; Berit Lilienthal Heitmann
Source:
Nutrients 2019 v.11 no.4 pp. -
ISSN:
2072-6643
Subject:
asthma; boys; childhood; children; data analysis; epidemiological studies; experimental design; gender differences; immune response; issues and policy; lungs; margarine; maternal exposure; phenotype; pregnancy; risk reduction; vitamin D; vitamin D deficiency; women
Abstract:
... Prenatal vitamin D insufficiency may be associated with an increased risk of developing childhood asthma. Results from epidemiological studies are conflicting and limited by short follow-up and small sample sizes. The objective of this study was to examine if children born to women exposed to the margarine fortification policy with a small dose of extra vitamin D during pregnancy had a reduced ris ...
DOI:
10.3390/nu11040924
PubMed:
31022976
PubMed Central:
PMC6521227

97. Factors influencing the gut microbiome in children: from infancy to childhood

Author:
Shreyas V Kumbhare; Dhrati V Patangia; Ravindra H Patil; Yogesh S Shouche; Nitinkumar P Patil
Source:
Journal of biosciences 2019 v.44 no.2 pp. 49
ISSN:
0250-5991
Subject:
adults; asthma; childhood; children; diabetes; dysbiosis; fetus; humans; immune system; infancy; intestinal microorganisms; microbial communities; obesity
Abstract:
... The human microbiota plays a crucial role in educating the immune system and influencing host health right since birth. Various maternal factors along with the vertical microbial transfer from the mother, as well as the horizontal environmental transmission and internal factors relating to the infant, play a crucial role in modulating the gut microbiota. The early life microflora is highly unstabl ...
DOI:
10.1007/s12038-019-9860-z

98. Fish Consumption at One Year of Age Reduces the Risk of Eczema, Asthma and Wheeze at Six Years of Age

Author:
Torbjørn Øien; Astrid Schjelvaag; Ola Storrø; Roar Johnsen; Melanie Rae Simpson
Source:
Nutrients 2019 v.11 no.9 pp. -
ISSN:
2072-6643
Subject:
questionnaires; fish consumption; mothers; cod liver oil; eczema; pregnancy; children; asthma; fish; risk reduction; omega-3 fatty acids
Abstract:
... Background: The role of dietary fish and n-3 polyunsaturated fatty acids (n-PUFAs) in the primary prevention of allergic diseases remains uncertain. The aim of this study was to investigate associations between the consumption of fish and cod liver oil (rich in n-PUFAs) from pregnancy to the first two years of life, and parental reported allergic diseases at six years of age. Methods: We used data ...
DOI:
10.3390/nu11091969
PubMed:
31438628
PubMed Central:
PMC6770937

99. Genetic variants in 17q12-21 locus and childhood asthma in Brazil: Interaction with Varicella zoster virus seropositivity

Author:
Gustavo Nunes de Oliveira Costa; Camila Alexandrina Figueiredo; Jackson Santos Conceição; Agostino Strina; Bernd Genser; Thiago Magalhaes da Silva; Neuza Maria Alcantara-Neves; Rosemeire Leovigildo Fiaccone; Laura Cunha Rodrigues; Mauricio Lima Barreto
Source:
Gene 2019 v.715 pp. 143991
ISSN:
0378-1119
Subject:
Human alphaherpesvirus 3; asthma; atopy; childhood; children; cross-sectional studies; genetic models; genetic predisposition to disease; genetic variation; genome; genome-wide association study; genotyping; loci; public health; risk; seroprevalence; Brazil
Abstract:
... Asthma is a complex disease with worldwide public health relevance, is related to environmental causes and a genetic predisposition. The chromosomal 17q12-21 locus has been consistently demonstrated to be associated with asthma risk. The effects of variants in the 17q12-21 locus on childhood asthma were first identified in a genome wide- association study. Since that time, those findings have been ...
DOI:
10.1016/j.gene.2019.143991

100. Hebei Spirit oil spill and its long-term effect on children's asthma symptoms

Author:
Su Ryeon Noh; Jung-Ah Kim; Hae-Kwan Cheong; Mina Ha; Young-Koo Jee; Myung-Sook Park; Kyung-Hwa Choi; Ho Kim; Sung-Il Cho; Kyungho Choi; Domyung Paek
Source:
Environmental pollution 2019 v.248 pp. 286-294
ISSN:
0269-7491
Subject:
BTEX (benzene, toluene, ethylbenzene, xylene); accidents; asthma; benzene; children; confidence interval; ethylbenzene; long term effects; middle school students; odds ratio; oil spills; petroleum; questionnaires; residential areas; toluene; xylene; China
Abstract:
... On December 7th, 2007, an estimated 12,547 kL of crude oil was spilled from the collision of Hebei Spirit near residential area. Our previous study demonstrated worsening of children's asthma symptoms one year after the accident. This study investigated long-term effect of the oil spill on children's asthma symptoms up to five years after the accident. All elementary and middle school students in ...
DOI:
10.1016/j.envpol.2019.02.034