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1. 2q35-rs13387042 variant and the risk of breast cancer: a case–control study

Author:
Abolfazl Nesaei; Zari Naderi Ghale-noie; Asma Khorshid Shamshiri; Fahimeh Afzaljavan; Mahdi Rivandi; Amir Tajbakhsh; Fatemeh Homaei Shandiz; Alireza Pasdar
Source:
Molecular biology reports 2022 v.49 no.5 pp. 3549-3557
ISSN:
0301-4851
Subject:
DNA; alleles; blood; breast neoplasms; breasts; carcinogenesis; case-control studies; demographic statistics; etiology; genetic background; genotyping; histopathology; lifestyle; molecular biology; risk; risk assessment; statistical analysis
Abstract:
... BACKGROUND: Breast Cancer is the most frequent neoplasm diagnosed among women worldwide. Genetic background and lifestyle/environment play a significant role in the disease etiology. According to Genome-wide association studies, some single-nucleotide polymorphisms such as 2q35-rs13387042–(G/A) have been introduced to be associated with breast cancer risk and features. In this study, we aimed to e ...
DOI:
10.1007/s11033-022-07195-6

2. African Swine Fever Outbreaks in Lithuanian Domestic Pigs in 2019

Author:
Alvydas Malakauskas; Katja Schulz; Indrė Kukanauskaitė; Marius Masiulis; Franz Josef Conraths; Carola Sauter-Louis
Source:
Animals 2022 v.12 no.1 pp. -
ISSN:
2076-2615
Subject:
African swine fever; biosecurity; case-control studies; confidence interval; equipment; farms; mushrooms; odds ratio; regression analysis; swine; viruses; Lithuania
Abstract:
... While numerous risk factors of African swine fever (ASF) transmission to domestic pigs have been described, ASF virus introduction has often not been traced back to one single defined cause. The large number of ASF outbreaks that occurred in domestic pigs in Lithuania from 2014 through to 2018 raised the question regarding whether outbreak-specific risk factors and transmission routes could be ide ...
DOI:
10.3390/ani12010115

3. Airway smooth muscle remodelling in mild and moderate equine asthma

Author:
Florence Dupuis‐Dowd; Jean‐Pierre Lavoie
Source:
Equine veterinary journal 2022 v.54 no.5 pp. 865-874
ISSN:
0425-1644
Subject:
asthma; biomarkers; case-control studies; cell proliferation; horses; hospitals; hyperplasia; hypertrophy; immunohistochemistry; inflammation; myocytes; myosin heavy chains; smooth muscle
Abstract:
... BACKGROUND: Airway smooth muscle remodelling in severe equine asthma includes both thickening of airway smooth muscle, resulting from hyperplasia and hypertrophy, and changes in contractility. However, airway smooth muscle changes have not been studied in milder forms of the disease. OBJECTIVES: To investigate bronchial smooth muscle remodelling in horses with mild and moderate asthma (MEA). STUDY ...
DOI:
10.1111/evj.13514

4. Alteration of gut bacteria composition among individuals with asymptomatic Blastocystis infection: A case-control study

Author:
Sahar Behboud; Kavous Solhjoo; Saiedeh Erfanian; Majid Pirestani; Amir Abdoli
Source:
Microbial pathogenesis 2022 v.169 pp. 105639
ISSN:
0882-4010
Subject:
Bacteroides fragilis; Bifidobacterium; Blastocystis; Enterococcus; Escherichia coli; Lactobacillus; Ruminococcus productus; case-control studies; cross-sectional studies; digestive tract; ecosystems; gastrointestinal system; humans; intestinal microorganisms; parasites; pathogenesis; quantitative polymerase chain reaction
Abstract:
... The gut microbiota consists a diverse and complex ecosystem that is involved in beneficial functions as well as potentially harmful conditions for human. Blastocystis sp. is a common parasite of the digestive tract of animals and humans; however, limited data is available concerning the association of asymptomatic Blastocystis infection and gut bacteria composition. Hence, in this cross-sectional ...
DOI:
10.1016/j.micpath.2022.105639

5. Anti-androgenic compounds in breast milk and cryptorchidism among Norwegian boys in the HUMIS birth cohort

Author:
Bérénice Collet; Anteneh A. Desalegn; Kees Swart; Matthijs Naderman; Nina Iszatt; Hein Stigum; Tina K. Jensen; Abraham Brouwer; Merete Eggesbø; Bart van der Burg
Source:
Science of the total environment 2022 v.803 pp. 149746
ISSN:
0048-9697
Subject:
androgen receptors; breast feeding; breast milk; case-control studies; cryptorchidism; environment; hormone antagonists; humans; milk; regression analysis; testes
Abstract:
... The prevalence of cryptorchidism has increased over the past decades, yet its origins remain poorly understood. Testis descent is dependent on androgens and likely affected by endocrine disrupting compounds (EDCs), targeting the androgen receptor (AR). We investigated the association between anti-androgenic activity, not derived from natural hormones, in maternal breast milk and impaired testis de ...
DOI:
10.1016/j.scitotenv.2021.149746

6. Are dietary factors involved in the association of CDH4 methylation and breast cancer risk?

Author:
Nannan Zhang; Liangliang Li; Zhiping Long; Jinghang Du; Shuo Li; Huihui Yin; Kun Xie; Zhen Wu; Yanbo Chen; Daria Volontovich; Huijie Cheng; Fan Wang
Source:
British journal of nutrition 2022 v.127 no.12 pp. 1868-1877
ISSN:
1475-2662
Subject:
DNA; DNA methylation; breast neoplasms; breasts; cadherins; case-control studies; cell adhesion; epigenetics; fish; food intake; glycoproteins; leukocytes; milk; physical activity; pork; regression analysis; risk; risk reduction
Abstract:
... DNA methylation is one of the most important epigenetic modifications in breast cancer (BC) development, and long-term dietary habits can alter DNA methylation. Cadherin-4 (CDH4, a member of the cadherin family) encodes Ca²⁺-dependent cell–cell adhesion glycoproteins. We conducted a case–control study (380 newly diagnosed BC and 439 cancer-free controls) to explore the relationship of CDH4 methyla ...
DOI:
10.1017/S0007114521002804

7. Aryl hydrocarbon receptor activity in human breast milk and cryptorchidism: A case-control study within the prospective Norwegian HUMIS cohort

Author:
Anteneh Assefa Desalegn; Bérénice Collet; Nina Iszatt; Hein Stigum; Tina K. Jensen; Lydia Jonker; Harrie Besselink; Bart van der Burg; Merete Eggesbø
Source:
Environmental research 2022 v.214 pp. 113861
ISSN:
0013-9351
Subject:
aryl hydrocarbon receptors; body weight; breast feeding; breast milk; bromination; case-control studies; cryptorchidism; dioxins; estrogens; etiology; lipids; milk; perfluorocarbons; regression analysis; research
Abstract:
... The etiology of cryptorchidism remains poorly understood. Endocrine disrupting chemicals can impact estrogen signaling by interacting with aryl hydrocarbon receptor (AhR) activity. To evaluate whether AhR activity in breast milk samples is associated with cryptorchidism. We conducted a case-control study based on 199 mother-child pairs (n = 91 cases/108 controls) selected from the Norwegian Human ...
DOI:
10.1016/j.envres.2022.113861

8. The Association Among Maternal Index of Nutritional Quality, Dietary Antioxidant Index, and Odds of Miscarriage Incidence: Case-Control Study

Author:
Farhad Vahid; Diana Rahmani; Sayed Hossein Davoodi; Azita Hekmatdoost
Source:
Journal of the American Nutrition Association 2022 v.41 no.3 pp. 310-317
ISSN:
2769-707X
Subject:
abortion (animals); antioxidants; ascorbic acid; case-control studies; diet; fetus; niacin; nutritive value; pregnancy; protective effect; questionnaires; risk; selenium; standard deviation; vitamin B12; vitamin E; zinc
Abstract:
... Miscarriage is a pregnancy condition in which the fetus or embryo naturally dies before being able to survive independently. According to studies, diet and dietary factors are associated with the risk of miscarriage (pregnancies <20 weeks). A 168-item semi-quantitative feed frequency questionnaire was used to estimate the Dietary Antioxidant Index (DAI) and the Index of Nutritional Quality (INQ). ...
DOI:
10.1080/07315724.2021.1880987

9. Association Between Essential Metal Elements and the Risk of Autism in Chinese Han Population

Author:
Jiahui Ma; Jing Wu; Haibin Li; Jingyu Wang; Jisheng Han; Rong Zhang
Source:
Biological trace element research 2022 v.200 no.2 pp. 505-515
ISSN:
0163-4984
Subject:
Chinese people; autism; blood serum; calcium; case-control studies; cobalt; copper; dose response; homeostasis; humans; iron; magnesium; manganese; molybdenum; neurodevelopment; potassium; research; risk; selenium; sodium; zinc; China
Abstract:
... Essential metal elements (EMEs) have essential roles in neurological development and maintenance of human homeostasis. We performed a case-control study to explore association between the risk of autism spectrum disorder (ASD) and the 11 EMEs [Calcium (Ca), potassium (K), magnesium (Mg), sodium (Na), manganese (Mn), selenium (Se), cobalt (Co), Molybdenum (Mo), copper (Cu), zinc (Zn), and iron (Fe) ...
DOI:
10.1007/s12011-021-02690-6

10. Association Between Osteoarthritis and Water Fluoride Among Tongyu Residents, China, 2019: a Case–Control of Population-Based Study

Author:
Alphonse Sowanou; Xinyue Meng; Nan Zhong; Yongzheng Ma; Ailin Li; Jian Wang; Hanying Li; Junrui Pei; Yanhui Gao
Source:
Biological trace element research 2022 v.200 no.7 pp. 3107-3116
ISSN:
0163-4984
Subject:
adults; cartilage; case-control studies; fluorides; osteoarthritis; regression analysis; research; risk; trace elements; China
Abstract:
... Fluoride is an environmental chemical that has adverse effects on articular cartilage, probably increasing osteoarthritis (OA) risk. However, this association still needs more epidemiological evidence to clarify. The aim of this study was to determine the relationships between chronic fluoride exposure and OA risk among the residents living in Tongyu County, China, 2019, with a frequency-matched c ...
DOI:
10.1007/s12011-021-02937-2

11. The Association between Consumption of Dairy-Originated Digestion Resistant and Bioactive Peptides and Breast Cancer Risk: A Case-Control Study

Author:
Masoumeh Jabbari; Meisam Barati; Mahdi Shabani; Elham Kazemian; Sajad Khalili-Moghadam; Fardin Javanmardi; Elaheh Hatami; Reihaneh Zeinalian; Sayed Hossein Davoodi; Bahram Rashidkhani; Shima Jafarzadeh; Elcin Huseyn; Amin Mousavi Khaneghah
Source:
Nutrition and cancer 2022 v.74 no.7 pp. 2426-2435
ISSN:
1532-7914
Subject:
bioactive properties; breast neoplasms; case-control studies; chronic diseases; computer simulation; dairy consumption; digestibility; hydrophilicity; ingredients; models; observational studies; peptides; regression analysis; risk; risk assessment; Iran
Abstract:
... Bioactive peptides (BPs) content of dairy products is suggested to be a significant ingredient for reducing breast cancer (BC) risk. There is no observational study regarding the correlation between BPs and the risk of chronic disease because BPs’ content of food items has not been evaluated in any study. The goal of the current study was to assess the association of dairy-originated BPs with BC r ...
DOI:
10.1080/01635581.2021.2009884

12. The Association between Dietary Calcium Intake and Breast Cancer Risk among Iranian Women

Author:
Soraiya Ebrahimpour-Koujan; Sanaz Benisi-Kohansal; Leila Azadbakht; Ahmad Esmaillzadeh
Source:
Nutrition and cancer 2022 v.74 no.5 pp. 1652-1659
ISSN:
1532-7914
Subject:
breast neoplasms; breasts; calcium; case-control studies; dietary calcium; energy intake; postmenopause; premenopause; risk
Abstract:
... No information is available from Middle Eastern countries linking dietary calcium intake and odds of breast cancer. This study was conducted to investigate the association between dietary calcium intake and odds of having breast cancer among Iranian women. In this population-based case-control study, 350 newly diagnosed breast cancer cases were recruited and 700 age-matched subjects were enrolled ...
DOI:
10.1080/01635581.2021.1957135

13. The Association between Dietary Diversity Score and Risk of Prostate Cancer: (A Case-Control Study)

Author:
Fatemeh Mirjalili; Mahsa Rezazadegan; Yahya Jalilpiran; Seyed Mohammad Mousavi; Alireza Jafari; Seyed Amir Reza Mohajeri; Shiva Faghih
Source:
Nutrition and cancer 2022 v.74 no.4 pp. 1270-1278
ISSN:
1532-7914
Subject:
body mass index; case-control studies; education; energy intake; food frequency questionnaires; meat; physical activity; prostatic neoplasms; regression analysis; risk; risk assessment
Abstract:
... There are few studies that evaluated the relationship between dietary diversity score (DDS) and risk of cancer. The purpose of this study was to examine the association of DDS with the risk of prostate cancer (PC) among Iranian men. This case-control study was performed among 60 cases with prostate cancer and 60 hospital-based controls. Anthropometric measurements were done and demographic informa ...
DOI:
10.1080/01635581.2021.1952448

14. The Association between Dietary Inflammatory Potential and Gastric Cancer: A Case Control Study

Author:
Ahmad Mujtaba Barekzai; Azadeh Aminianfar; Seyed Mohammad Mousavi; Ahmad Esmaillzadeh
Source:
Nutrition and cancer 2022 v.74 no.2 pp. 463-471
ISSN:
1532-7914
Subject:
anti-inflammatory activity; case-control studies; food frequency questionnaires; hospitals; nutrition assessment; risk; stomach neoplasms; Afghanistan
Abstract:
... No report is available about diet-disease associations in the understudied region of Afghanistan. Although the inflammatory potential of diet has been linked with several cancers, information about gastric cancer is scarce. The present study aimed to investigate the relationship between the inflammatory potential of the diet and odds of gastric cancer in Afghanistan. In this hospital-based case-co ...
DOI:
10.1080/01635581.2021.1883682

15. The Association between Dietary Insulin Index and Load with Gastric Cancer in Afghanistan

Author:
Freshta Amiry; Ahmad Mujtaba Barekzai; Azadeh Aminianfar; Ahmad Esmaillzadeh
Source:
Nutrition and cancer 2022 v.74 no.7 pp. 2489-2498
ISSN:
1532-7914
Subject:
Helicobacter pylori; case-control studies; food frequency questionnaires; hospitals; insulin; nutrition assessment; pathogenesis; people; regression analysis; stomach neoplasms; Afghanistan
Abstract:
... Insulin has a critical role in the pathogenesis of several cancers. We are aware of no study that examined the association between dietary insulin index (DII) and dietary insulin load (DIL) and gastric cancer. This study aimed to investigate the relationship between dietary insulin index and DIL and odds of gastric cancer in Afghanistan. In this hospital-based case-control study, we recruited 90 p ...
DOI:
10.1080/01635581.2021.2014906

16. Association between TAP gene polymorphisms and tuberculosis susceptibility in a Han Chinese population in Guangdong

Author:
Fang Luo; PinAng Zou; Yinqian Liao; Jiaze Luo; Dan Luo; Kuan Hu; KaiXuan Zhang; BaoGuo Wang
Source:
Molecular genetics and genomics 2022 v.297 no.3 pp. 779-790
ISSN:
1617-4615
Subject:
Chinese people; blood; case-control studies; genomics; genotyping; haplotypes; humidity; peptides; polymerase chain reaction; public health; risk; tuberculosis; China
Abstract:
... Tuberculosis (TB) is an important public health problem. Studies indicated that TAP plays a key role in the presentation and transport of antigenic peptides during anti-M.tb infection. Given the important biological role of the TAP gene involved in anti-M.tb infection, a family-based case–control study including 133 tuberculosis patients, 107 healthy household contacts, and 173 healthy controls wa ...
DOI:
10.1007/s00438-022-01885-3

17. Association between UBAC2 gene polymorphism and the risk of noise-induced hearing loss: a cross-sectional study

Author:
Liu Wan; Ludi Zhang; Peng Sun; Lei Han; Hengdong Zhang; Baoli Zhu; Boshen Wang
Source:
Environmental science and pollution research 2022 v.29 no.22 pp. 32947-32958
ISSN:
0944-1344
Subject:
DNA; alleles; case-control studies; computer software; cross-sectional studies; fluorescence; genotyping; haplotypes; luciferase; pollution; polymerase chain reaction; regression analysis; research; risk; single nucleotide polymorphism; transcription factors
Abstract:
... The purpose of this article was to investigate the association between the ubiquitin-associated domain-containing protein 2 (UBAC2) gene polymorphism and noise-induced hearing loss (NIHL) and to further explore the role of single-nucleotide polymorphism (SNP) in UBAC2 in NIHL. A case control study involving 660 NIHL cases and 581 controls was conducted in this research. After genotyping by multipl ...
DOI:
10.1007/s11356-021-18360-y

18. Association between congenital heart defects and maternal manganese and iron concentrations: a case–control study in China

Author:
Meixian Wang; Yan Tian; Ping Yu; Nana Li; Ying Deng; Lu Li; Hong Kang; Dapeng Chen; Hui Wang; Zhen Liu; Juan Liang
Source:
Environmental science and pollution research 2022 v.29 no.18 pp. 26950-26959
ISSN:
0944-1344
Subject:
case-control studies; children; heart; iron; manganese; models; pollution; regression analysis; research; risk; China
Abstract:
... To investigate the correlation between maternal manganese and iron concentrations and the risk of CHD among their infant. A multi-center hospital-based case control study was conducted in China. There were 322 cases and 333 controls have been selected from pregnant women who received prenatal examinations. Correlations between CHDs and maternal manganese and iron concentrations were estimated by c ...
DOI:
10.1007/s11356-021-17054-9

19. Association between early-pregnancy serum C-peptide and risk of gestational diabetes mellitus: a nested case–control study among Chinese women

Author:
Xue Yang; Yi Ye; Yi Wang; Ping Wu; Qi Lu; Yan Liu; Jiaying Yuan; Xingyue Song; Shijiao Yan; Xiaorong Qi; Yi-Xin Wang; Ying Wen; Gang Liu; Chuanzhu Lv; Chun-Xia Yang; An Pan; Jianli Zhang; Xiong-Fei Pan
Source:
Nutrition & metabolism 2022 v.19 no.1 pp. 56
ISSN:
1743-7075
Subject:
adiponectin; biomarkers; blood glucose; blood serum; c-peptide; case-control studies; confidence interval; gestational age; gestational diabetes; glycosylation; hemoglobin; high density lipoprotein cholesterol; insulin resistance; leptin; low density lipoprotein cholesterol; model validation; models; nutrition; odds ratio; regression analysis; risk; systolic blood pressure; waist-to-hip ratio
Abstract:
... OBJECTIVE: To examine the association of early-pregnancy serum C-peptide with incident gestational diabetes mellitus (GDM) and the predictive ability of maternal C-peptide for GDM. METHODS: A nested case–control study of 332 GDM cases and 664 controls was established based on the Tongji-Shuangliu Birth Cohort. The GDM cases and controls were matched at 1:2 on maternal age (± 3 years) and gestation ...
DOI:
10.1186/s12986-022-00691-3

20. Association between genetic variations of mitochondrial isocitrate dehydrogenase (IDH2) and acute myocardial infarction

Author:
Mona M. Watany; Rania Nagi Abd-Ellatif; Mohamed Ezzelregal Abdeldayem; Hemat El-sayed El-Horany
Source:
Gene 2022 v.829 pp. 146497
ISSN:
0378-1119
Subject:
atherogenesis; biomarkers; case-control studies; enzyme activity; genes; heterozygosity; isocitrate dehydrogenase; lipid peroxides; low density lipoprotein; malondialdehyde; mitochondria; mutants; myocardial infarction; oxidative stress; risk factors
Abstract:
... Mitochondrial isocitrate dehydrogenase (IDH2) is a major contributor to cellular redox control. The aim of this study was to preliminary link IDH2 genetic variations to redox imbalance, atherogenesis and risk of acute myocardial infarction (AMI). This case-control study included 120 AMI patients and 120 healthy controls. IDH2 genetic variations were tested using direct sequencing. IDH2 enzyme acti ...
DOI:
10.1016/j.gene.2022.146497