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You searched for: Subject chemical structure Remove constraint Subject: chemical structure Subject lignans Remove constraint Subject: lignans
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1. (+)-Episesaminone, a Sesamum indicum furofuran lignan. Isolation and hemisynthesis

Author:
Marchand, P.A.; Kato, M.J.; Lewis, N.G.
Source:
Journal of natural products 1997 v.60 no.11 pp. 1189-1192
ISSN:
0163-3864
Subject:
Sesamum indicum; seeds; furans; lignans; spectral analysis; chemical structure; biosynthesis; biochemical pathways; chemical reactions; chemical constituents of plants
DOI:
10.1021/np9702953

2. 10-Demethoxystegane, a new lignan from Steganotaenia araliacea

Author:
Meragelman, K.M.; McKee, T.C.; Boyd, M.R.
Source:
Journal of natural products 2001 v.64 no.11 pp. 1480-1482
ISSN:
0163-3864
Subject:
Apiaceae; lignans; lactones; spectral analysis; chemical structure; antineoplastic agents; humans; ovarian diseases; chemical constituents of plants; Tanzania
DOI:
10.1021/np010248h
PubMed:
11720541

3. 5-Methoxyjusticidin A, a new arylnaphthalene lignan from Protium unifoliolatum

Author:
Siani, A.C.; Zoghbi, M. das G.B.; Wolter, E.L.A.; Vencato, I.
Source:
Journal of natural products 1998 v.61 no.6 pp. 796-797
ISSN:
0163-3864
Subject:
Burseraceae; medicinal plants; wood; naphthalene; lignans; spectral analysis; chemical structure; chemical constituents of plants; Brazil
DOI:
10.1021/np9702291
PubMed:
9644067

4. 6-Methoxypodophyllotoxin-7-O-n-hexanoate, a new aryltetralin lignan ester from seeds of Linum flavum

Author:
Klaes, Michael; Ellendorff, Therese; Schmidt, Thomas J.
Source:
Planta medica 2010 v.76 no.7 pp. 719-721
ISSN:
0032-0943
Subject:
Linum flavum; seeds; chemical constituents of plants; lignans; esters; spectral analysis; chemical structure; plant extracts
DOI:
10.1055/s-0029-1240674
PubMed:
19960414

5. Abscisic acid related compounds and lignans in prunes (Prunus domestica L.) and their oxygen radical absorbance capacity (ORAC)

Author:
Kikuzaki, H.; Kayano, S.; Fukutsuka, N.; Aoki, A.; Kasamatsu, K.; Yamasaki, Y.; Mitani, T.; Nakatani, N.
Source:
Journal of agricultural and food chemistry 2004 v.52 no.2 pp. 344-349
ISSN:
0021-8561
Subject:
prunes; plant extracts; abscisic acid; lignans; glucosides; chemical structure; antioxidant activity; free radicals; antioxidants
Abstract:
... Four new abscisic acid related compounds (1-4), together with (+)-abscisic acid (5), (+)-β-D-glucopyranosyl abscisate (6), (6S,9R)-roseoside (7), and two lignan glucosides ((+)-pinoresinol mono-β-D-glucopyranoside (8) and 3-(β-D-glucopyranosyloxymethyl)-2- (4-hydroxy-3-methoxyphenyl)-5-(3-hydroxypropyl)-7-methoxy-(2R,3S)-dihydrobenzofuran (9)) were isolated from the antioxidative ethanol extract o ...
DOI:
10.1021/jf034954v

6. Absolute configuration of (+)-pinoresinol 4-O-[6"-O-galloyl]-β-d-glucopyranoside, macarangiosides E, and F isolated from the leaves of Macaranga tanarius

Author:
Matsunami, Katsuyoshi; Otsuka, Hideaki; Kondo, Kazunari; Shinzato, Takakazu; Kawahata, Masatoshi; Yamaguchi, Kentaro; Takeda, Yoshio
Source:
Phytochemistry 2009 v.70 no.10 pp. 1277-1285
ISSN:
0031-9422
Subject:
Macaranga tanarius; lignans; glucosides; chemical constituents of plants; chemical structure; spectral analysis; stereochemistry; antioxidant activity; Japan
Abstract:
... A lignan glucoside, (+)-pinoresinol 4-O-[6"-O-galloyl]-β-d-glucopyranoside (1), and two megastigmane glucosides, named macarangiosides E and F (2, 3), together with 15 known compounds (4-18) were isolated from leaves of Macaranga tanarius (L.) Müll.-Arg. (Euphorbiaceae). Their structures were elucidated by spectroscopic and chemical analyses. In addition, the absolute stereochemistry of macarangi ...
DOI:
10.1016/j.phytochem.2009.07.020

7. Agastinol and agastenol, novel lignans from Agastache rugosa and their evaluation in an apoptosis inhibition assay

Author:
Lee, C.H.; Kim, H.; Kho, Y.H.
Source:
Journal of natural products 2002 v.65 no.3 pp. 414-416
ISSN:
0163-3864
Subject:
Agastache; medicinal plants; lignans; spectral analysis; chemical structure; apoptosis; leukemia; cell lines; chemical constituents of plants; South Korea
DOI:
10.1021/np010425e
PubMed:
11908994

8. Aglacins A-D, first representatives of a new class of aryltetralin cyclic ether lignans from Aglaia cordata

Author:
Wang, B.G.; Ebel, R.; Nugroho, B.W.; Prijono, D.; Frank, W.; Steube, K.G.; Hao, X.J.; Proksch, P.
Source:
Journal of natural products 2001 v.64 no.12 pp. 1521-1526
ISSN:
0163-3864
Subject:
Aglaia; stems; bark; lignans; ethers; metabolites; spectral analysis; chemical structure; chemical constituents of plants; Indonesia
DOI:
10.1021/np0102962
PubMed:
11754603

9. Alkyl and phenylalkyl anacardic acids from Knema elegans seed oil

Author:
Spencer, G.F.; Tjarks, L.W.; Kleiman, R.
Source:
Journal of natural products 1980 v.43 no.6 pp. 724-730
ISSN:
0163-3864
Subject:
myristic acid; fatty acid composition; seed oils; Myristicaceae; lignans; resorcinols; chemical structure; salicylic acids
DOI:
10.1021/np50012a005
PubMed:
20707395

10. Americanin, a bioactive dibenzylbutyrolactone lignan, from the seeds of Centaurea americana

Author:
Shoeb, M.; MacManus, S.M.; Kumarasamy, Y.; Jaspars, M.; Nahar, L.; Thoo-Lin, P.K.; Nazemiyeh, H.; Sarker, S.D.
Source:
Phytochemistry 2006 v.67 no.21 pp. 2370-2375
ISSN:
0031-9422
Subject:
Centaurea; seeds; Artemia; chemotaxonomy; plant extracts; dioxins; toxicity testing; lignans; spectral analysis; antioxidant activity; plant taxonomy; chemical structure
Abstract:
... The reversed-phase preparative HPLC analysis of the methanol (MeOH) extract of the seeds of Centaurea americana afforded a dibenzylbutyrolactone lignan, 3"-O-caffeoyl arctiin (named americanin), together with five known lignans, arctiin, arctigenin, matairesinol, matairesinoside and lappaol A, and two known phytoecdysteroids, 20-hydroxyecdysone and makisterone A. While the structures of the known ...
DOI:
10.1016/j.phytochem.2006.08.012
PubMed:
16996096

11. Analysis and identification of lignans in Phyllanthus urinaria by HPLC-SPE-NMR

Author:
Wang, C.Y.; Lee, S.S.
Source:
Phytochemical analysis 2005 v.16 no.2 pp. 120-126
ISSN:
0958-0344
Subject:
Phyllanthus urinaria; plant extracts; phytochemicals; lignans; chemical structure; chemical analysis; reversed-phase high performance liquid chromatography; nuclear magnetic resonance spectroscopy
Abstract:
... HPLC-SPE-NMR has been applied to the analysis of a number of structurally similar lignans present in Phyllanthus urinaria. A reversed-phase HPLC system, using a C8 column eluted with tetrahydrofuran-water-methanol and detected at 225 nm was developed that gave good resolution for seven lignans from Phyllanthus urinaria. Coupling of this system with SPE-NMR provided clean 1H-NMR spectra for nine li ...
DOI:
10.1002/pca.830
PubMed:
15881120

12. Anti-HIV lignans from Justicia procumbens

Author:
Xin-Ya XU; Dong-Ying WANG; Chuen-Fai KU; Yang ZHAO; Han CHENG; Kang-Lun LIU; Li-Jun RONG; Hong-Jie ZHANG
Source:
Chinese journal of natural medicines 2019 v.17 no.12 pp. 945-952
ISSN:
1875-5364
Subject:
Human immunodeficiency virus 1; Justicia procumbens; Oriental traditional medicine; acetates; antiretroviral properties; chemical structure; cytotoxicity; inhibitory concentration 50; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... Twenty-one lignans including three new ones (1, 2 and 13) were isolated from Justicia procumbens. The chemical structures of the new lignans were determined by spectroscopic means including 1D and 2D NMR analysis. These compounds were evaluated for their cytotoxic and anti-HIV activities. The new secoisolariciresinol dimethyl ether acetate (13) exhibited anti-HIV-1 activity with an IC50 value of 5 ...
DOI:
10.1016/S1875-5364(19)30117-7

13. Anti-complement activity of norlignans and terpenes from the stem bark of Styrax japonica

Author:
Min, B.S.; Oh, S.R.; Ahn, K.S.; Kim, J.H.; Lee, J.; Kim, D.Y.; Kim, E.H.; Lee, H.K.
Source:
Planta medica 2004 v.70 no.12 pp. 1210-1215
ISSN:
0032-0943
Subject:
terpenoids; complement; human health; lignans; spectral analysis; hemolysis; medicinal properties; stereochemistry; chemical structure; Styrax japonicus; South Korea
DOI:
10.1055/s-2004-835853
PubMed:
15643559

14. Anti-inflammatory Neolignans from Piper kadsura

Author:
Lin, L.C.; Shen, C.C.; Shen, Y.C.; Tsai, T.H.
Source:
Journal of natural products 2006 v.69 no.5 pp. 842-844
ISSN:
0163-3864
Subject:
anti-inflammatory activity; biosynthesis; humans; reactive oxygen species; tyramine; plant extracts; medicinal plants; human health; neutrophils; cultured cells; lignans; spectral analysis; antioxidant activity; chemical structure; Oriental traditional medicine; Piper; Taiwan
DOI:
10.1021/np0505521
PubMed:
16724856

15. Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii

Author:
Ma, J.; Dey, M.; Yang, H.; Poulev, A.; Pouleva, R.; Dorn, R.; Lipsky, P.E.; Kennelly, E.J.; Raskin, I.
Source:
Phytochemistry 2007 v.68 no.8 pp. 1172-1178
ISSN:
0031-9422
Subject:
anti-inflammatory activity; nitric oxide synthase; Tripterygium wilfordii; interleukin-1; phytochemicals; immunosuppression; macrophages; medicinal plants; mice; lignans; spectral analysis; prostaglandin synthase; gene expression regulation; stereochemistry; chemical structure; Oriental traditional medicine; China
Abstract:
... The extract of Tripterygium wilfordii Hook F. (TwHF), which showed anti-inflammatory and immunosuppressive activities in human clinical trials for rheumatoid arthritis, was subjected to the activity-guided fractionation and spectroscopic characterization of bioactives. A tetrahydrofuran lignan, tripterygiol (1), and eight known compounds, all capable of suppressing pro-inflammatory gene expression ...
DOI:
10.1016/j.phytochem.2007.02.021
PubMed:
17399748

16. Anti-inflammatory flavonolignans from Hydnocarpus anthelminthica seeds

Author:
Jun-Feng Wang; Ge-Fen Yin; Xiao-Jiang Zhou; Jia Su; Yan Li; Hui-Min Zhong; Gang Duan; Yong-Xian Cheng
Source:
Journal of Asian natural products research 2011 v.13 no.1 pp. 80-83
ISSN:
1477-2213
Subject:
Hydnocarpus; anti-inflammatory activity; bioassays; chemical structure; flavonoids; inhibitory concentration 50; lignans; nitric oxide; plant extracts; seeds; spectral analysis
Abstract:
... A new flavonolignan, anthelminthicol A (1), together with four known compounds, was isolated from the EtOAc extracts of the seeds of Hydnocarpus anthelminthica. Their structures were elucidated using extensive spectroscopic techniques. Bioassay showed that compounds 3–5 could inhibit nitric oxide production in LPS-stimulated RAW 264.7 macrophage cell lines, with IC₅₀ values of 7.81, 9.38, and 10.5 ...
DOI:
10.1080/10286020.2010.543131

17. Anti-inflammatory properties of extracts, fractions and lignans isolated from Phyllanthus amarus

Author:
Kassuya, C.A.L.; Leite, D.F.P.; Melo, L.V. de; Rehder, V.L.G.; Calixto, J.B.
Source:
Planta medica 2005 v.71 no.8 pp. 721-726
ISSN:
0032-0943
Subject:
traditional medicine; anti-inflammatory activity; fractionation; interleukin-1; phytochemicals; medicinal plants; plant extracts; neutrophils; lignans; spectral analysis; edema; enzyme activity; peroxidase; chemical structure; Phyllanthus amarus
DOI:
10.1055/s-2005-871258
PubMed:
16142635

18. Antibacterial lignans and triterpenoids from Rostellularia procumbens

Author:
Zhang, Y.; Bao, F.; Hu, J.; Liang, S.; Du, G.; Zhang, C.; Cheng, Y.
Source:
Planta medica 2007 v.73 no.15 pp. 1596-1599
ISSN:
0032-0943
Subject:
humans; cytotoxicity; anticarcinogenic activity; medicinal plants; triterpenoids; lignans; cultured cells; spectral analysis; Justicia; chemical structure; Oriental traditional medicine; antibacterial properties; China
DOI:
10.1055/s-2007-993747
PubMed:
18058608

19. Antifungal, antiprotozoal, cytotoxic and piscicidal properties of justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum

Author:
Gertsch, J.; Tobler, R.T.; Brun, R.; Sticher, O.; Heilmann, J.
Source:
Planta medica 2003 v.69 no.5 pp. 420-424
ISSN:
0032-0943
Subject:
Phyllanthus; plant extracts; fractionation; phytochemicals; lignans; antifungal agents; antiprotozoal agents; antifungal properties; Aspergillus fumigatus; Aspergillus flavus; Candida albicans; Cryptococcus neoformans; Trypanosoma rhodesiense; Trypanosoma cruzi; Plasmodium falciparum; humans; cell lines; cytotoxicity; chemical structure; Venezuela
DOI:
10.1055/s-2003-39706
PubMed:
12802722

20. Antihepatitis activity (anti-HBsAg and anti-HBeAg) of C19 homolignans and six novel C18 dibenzocyclooctadiene lignans from Kadsura japonica

Author:
Kuo, Y.H.; Wu, M.D.; Huang, R.L.; Kuo, L.M.Y.; Hsu, Y.W.; Liaw, C.C.; Hung, C.C.; Shen, Y.C.; Ong, C.W.
Source:
Planta medica 2005 v.71 no.7 pp. 646-653
ISSN:
0032-0943
Subject:
Kadsura; plant extracts; phytochemicals; lignans; chemical structure; spectral analysis; stereochemistry; antiviral properties; viral hepatitis; Hepatitis B virus; viral antigens; cultured cells
DOI:
10.1055/s-2005-871271
PubMed:
16041651

21. Antihyperglycemic activity of phenylpropanoyl esters of catechol glycoside and its dimers from Dodecadenia grandiflora

Author:
Kumar, Manmeet; Rawat, Preeti; Rahuja, Neha; Srivastava, Arvind Kumar; Maurya, Rakesh
Source:
Phytochemistry 2009 v.70 no.11-12 pp. 1448-1455
ISSN:
0031-9422
Subject:
Laurales; esters; catechol; glycosides; lignans; acetylation; medicinal properties; glycemic effect; chemical structure; spectral analysis; acid hydrolysis; glucose tolerance; diabetes mellitus
Abstract:
... Bioactivity-guided separation of an antihyperglycemic extract from the leaves of Dodecadenia grandiflora afforded two phenylpropanoyl esters of catechol glycosides (1 and 4) and two lignane bis(catecol glycoside)esters (2 and 3). Their structures were established on the basis of extensive spectroscopic analysis (1D and 2D-NMR, MS). Compounds 2 and 3 are believed to be derived from dimerization via ...
DOI:
10.1016/j.phytochem.2009.07.029
PubMed:
19700178

22. Antihyperuricemic lignans from the leaves of Phyllanthus niruri

Author:
Murugaiyah, V.; Chan, K.L.
Source:
Planta medica 2006 v.72 no.14 pp. 1262-1267
ISSN:
0032-0943
Subject:
Euphorbiaceae; lignans; phytochemicals; spectral analysis; chemical structure; oral administration; dose response; blood chemistry; blood plasma; uric acid; rats; animal disease models; Phyllanthus niruri; Malaysia
DOI:
10.1055/s-2006-947224
PubMed:
16953466

23. Antimalarial Compounds from Grewia bilamellata

Author:
Ma, C.; Zhang, H.J.; Tan, G.T.; Hung, N.V.; Cuong, N.M.; Soejarto, D.D.; Fong, H.H.S.
Source:
Journal of natural products 2006 v.69 no.3 pp. 346-350
ISSN:
0163-3864
Subject:
Plasmodium falciparum; humans; cytotoxicity; plant extracts; Grewia; cultured cells; lignans; spectral analysis; chemical constituents of plants; antimalarials; chemical structure; stereochemistry; anticarcinogenic activity
DOI:
10.1021/np050313d
PubMed:
16562832

24. Antimalarial compounds from Rhaphidophora decursiva

Author:
Zhang, H.J.; Tamez, P.A.; Vu Dinh Hoang.; Ghee Teng Tan.; Nguyen van Hung.; Le Thi Xuan.; Le Mai Huong.; Nguyen Manh Cuong.; Do Thi Thao.; Soejarto, D.D.; Fong, H.H.S.; Pezzuto, J.M.
Source:
Journal of natural products 2001 v.64 no.6 pp. 772-777
ISSN:
0163-3864
Subject:
Rhaphidophora; medicinal plants; stems; leaves; lignans; peroxides; spectral analysis; chemical structure; medicinal properties; antimalarials; Plasmodium falciparum; chemical constituents of plants; Vietnam
DOI:
10.1021/np010037c
PubMed:
11421741

25. The Antioxidant Compounds from Urtica fissa Flowers

Author:
Mengyue Wang; Lili Wu; Hao Zhang; Dun Zhu Ci Ren; Tonghua Liu; Xiaobo Li
Source:
Chemistry of natural compounds 2019 v.55 no.5 pp. 839-842
ISSN:
0009-3130
Subject:
2,2-diphenyl-1-picrylhydrazyl; Urtica; antioxidants; chemical structure; flavonoids; flowers; lignans; median effective concentration; phenolic acids; spectral analysis
Abstract:
... Eleven compounds (1–11), including two new compounds (1, 2), were isolated from the antioxidant portion of the alcoholic extract of Urtica fissa flowers. Their chemical structures were elucidated from extensive spectroscopic analysis. The results of activity evaluation indicated that some compounds of phenolic acids (3, 4), flavonoids (7, 9, 10), and lignans (1, 6) possess significant activities o ...
DOI:
10.1007/s10600-019-02827-z

26. Antioxidant Lignans from Mananthes patentiflora

Author:
Tian, Junmian; Yang, Xianwen; Di, Yingtong; Ma, Yanlin; Li, Ling; Li, Lin; He, Hongping; Hao, Xiaojiang
Source:
Planta medica 2009 v.75 no.5 pp. 534-537
ISSN:
0032-0943
Subject:
Acanthaceae; lignans; glycosides; antioxidants; chemical structure; spectral analysis; stereochemistry; medicinal properties; antioxidant activity
DOI:
10.1055/s-0029-1185356
PubMed:
19219760

27. Antioxidant Lignans from the Fruits of Broussonetia papyrifera

Author:
Mei, Ren-Qiang; Wang, Yue-Hu; Du, Guan-Hua; Liu, Guang-Ming; Zhang, Li; Cheng, Yong-Xian
Source:
Journal of natural products 2009 v.72 no.4 pp. 621-625
ISSN:
0163-3864
Subject:
hydrogen peroxide; Broussonetia papyrifera; free radical scavengers; lignans; cell lines; antioxidant activity; chemical structure
DOI:
10.1021/np800488p
PubMed:
19296617

28. Antioxidant Phenylethanoid Glycosides and a Neolignan from Jacaranda caucana

Author:
Martin, Frederic; Hay, Anne-Emmanuelle; Condoretty, Valentin R. Quinteros; Cressend, Delphine; Reist, Marianne; Gupta, Mahabir P.; Carrupt, Pierre-Alain; Hostettmann, Kurt
Source:
Journal of natural products 2009 v.72 no.5 pp. 852-856
ISSN:
0163-3864
Subject:
fractionation; stems; plant extracts; free radical scavengers; lignans; antioxidant activity; Jacaranda; glycosides; chemical structure
DOI:
10.1021/np900038j
PubMed:
19361168

29. Antioxidant components as potential neuroprotective agents in sesame (Sesamum indicum L.)

Author:
Park, Si-Hyung; Ryu, Su-Noh; Bu, Youngmin; Kim, Hocheol; Simon, James E.; Kim, Kwan-Su
Source:
Food reviews international 2010 v.26 no.2 pp. 103-121
ISSN:
8755-9129
Subject:
Sesamum indicum; oilseed crops; oil crops; sesame seed; chemical constituents of plants; lignans; glucosides; vitamin content; tocopherols; neuroprotective effect; oxidative stability; antioxidants; antioxidant activity; chemical structure; biosynthesis; biochemical pathways
DOI:
10.1080/87559120903564464

30. Antioxidant furofuran lignans from Premna integrifolia

Author:
Deepti Yadav; Nusrat Masood; Suaib Luqman; Pemaiah Brindha; Madan M. Gupta
Source:
Industrial crops and products 2013 v.41 pp. 397-402
ISSN:
0926-6690
Subject:
Premna; acids; antioxidant activity; bark; catalpol; chemical structure; free radical scavengers; lignans; nuclear magnetic resonance spectroscopy; stems
Abstract:
... Two new furofuran lignans premnadimer (1) and 4β-hydroxyasarinin-1-O-β-glucopyranoside (2) along with 9 known compounds have been isolated from the stem bark of Premna integrifolia. Their chemical structures were elucidated using detailed spectroscopic studies. Their relative configurations were established using analysis of NOESY correlations and coupling constants observed in 1H NMR. Compounds 1 ...
DOI:
10.1016/j.indcrop.2012.04.044

31. Antioxidative catechol lignans converted from sesamin and sesaminol triglucoside by culturing with Aspergillus

Author:
Miyake, Y.; Fukumoto, S.; Okada, M.; Sakaida, K.; Nakamura, Y.; Osawa, T.
Source:
Journal of agricultural and food chemistry 2005 v.53 no.1 pp. 22-27
ISSN:
0021-8561
Subject:
biotransformation; metabolism; Aspergillus niger; free radicals; chemical structure; sesame seed; food biotechnology; lignans; Aspergillus awamori; antioxidant activity; food additives; antioxidants
Abstract:
... Sesamin and sesaminol triglucoside in sesame seeds are major lignans that display an abundance of biological activities. Although their antioxidative activity in vitro is weak, they have been reported to suppress oxidative stress in vivo. We investigated the production of new antioxidative lignans from sesame lignans by culturing with the genus Aspergillus to enhance the function of food materials ...
DOI:
10.1021/jf048743h

32. Antiplasmodial Securinega alkaloids from Phyllanthus fraternus: Discovery of natural (+)-allonorsecurinine

Author:
Gustav Komlaga; Grégory Genta-Jouve; Sandrine Cojean; Rita A. Dickson; Merlin L.K. Mensah; Philippe M. Loiseau; Pierre Champy; Mehdi A. Beniddir
Source:
Tetrahedron letters 2017 pp. -
ISSN:
0040-4039
Subject:
Phyllanthus fraternus; Plasmodium falciparum; Securinega; alkaloids; antimalarials; antiparasitic properties; chemical reactions; chemical structure; inhibitory concentration 50; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... The chemical investigation of the antimalarial plant Phyllanthus fraternus G. L. Webster (Phyllanthaceae) resulted in the discovery of the Securinega alkaloid (+)-allonorsecurinine (1), previously reported as a synthetic compound, together with the known ent-norsecurinine (2), nirurine (3), bubbialine (4), epibubbialine (5) and the lignan phyllanthin (6). The structure and absolute configuration o ...
DOI:
10.1016/j.tetlet.2017.08.045

33. Antiplasmodial activity of lignans and extracts from Pycnanthus angolensis

Author:
Abrantes, Marta; Mil-Homens, Tania; Duarte, Noelia; Lopes, Dinora; Cravo, Pedro; Madureira, Maria do Ceu; Ferreira, Maria-Jose U.
Source:
Planta medica 2008 v.74 no.11 pp. 1408-1412
ISSN:
0032-0943
Subject:
Myristicaceae; lignans; chemical structure; spectral analysis; Plasmodium falciparum
DOI:
10.1055/s-2008-1081317
PubMed:
18671202

34. Antiplatelet arylnaphthalide lignans from Justicia procumbens

Author:
Chen, C.C.; Hsin, W.C.; Ko, F.N.; Huang, Y.L.; Ou, J.C.; Teng, C.M.
Source:
Journal of natural products 1996 v.59 no.12 pp. 1149-1150
ISSN:
0163-3864
Subject:
medicinal plants; lignans; spectral analysis; chemical structure; anticoagulants; chemical constituents of plants; blood platelets; Taiwan
DOI:
10.1021/np960443+
PubMed:
8988600

35. Antiproliferative Compounds from Cleistanthus boivinianus from the Madagascar Dry Forest1

Author:
Liu Yixi; Young Kelly; Rakotondraibe L. Harinantenaina; Brodie Peggy J.; Wiley Jessica D.; Cassera Maria B.; Callmander Martin W.; Rakotondrajaona R.; Rakotobe Etienne; Rasamison Vincent E.; TenDyke Karen; Shen Yongchun; Kingston David G. I.
Source:
Journal of natural products 2015 v.78 no.7 pp. 1543-1547
ISSN:
1520-6025
Subject:
Cleistanthus; anticarcinogenic activity; chemical structure; colorectal neoplasms; humans; inhibitory concentration 50; lignans; melanoma; metastasis; neoplasm cells; ovarian neoplasms; spectroscopy; Madagascar
Abstract:
... The two new lignans 3α-O-(β-d-glucopyranosyl)desoxypodophyllotoxin (1) and 4-O-(β-d-glucopyranosyl)dehydropodophyllotoxin (2) were isolated from Cleistanthus boivinianus, together with the known lignans deoxypicropodophyllotoxin (3), (±)-β-apopicropodophyllin (4), (−)-desoxypodophyllotoxin (5), (−)-yatein (6), and β-peltatin-5-O-β-d-glucopyranoside (7). The structures of all compounds were charact ...
DOI:
10.1021/np501020m
PubMed:
26091020
PubMed Central:
PMC4517784
CHORUS:
10.1021/np501020m
Chorus Open Access:
10.1021/np501020m

36. Antiprotozoal compounds from Asparagus africanus

Author:
Oketch-Raban, H.A.; Dossaji, S.F.; Christensen, S.B.; Frydenvang, K.; Lemmich, E.; Cornett, C.; Olsen, C.E.; Chen, M.; Kharazmi, A.; Theander, T.
Source:
Journal of natural products 1997 v.60 no.10 pp. 1017-1022
ISSN:
0163-3864
Subject:
Asparagus (Asparagaceae); medicinal plants; roots; sapogenins; lignans; spectral analysis; chemical structure; antiprotozoal agents; Leishmania major; Plasmodium falciparum; leishmaniasis; chemical constituents of plants; Kenya
DOI:
10.1021/np970217f
PubMed:
9358645

37. Antitrypanosomal activity of a diterpene and lignans isolated from Aristolochia cymbifera

Author:
Sartorelli, Patricia; Carvalho, Camila Salomone; Reimao, Juliana Quero; Lorenzi, Harri; Tempone, Andre Gustavo
Source:
Planta medica 2010 v.76 no.13 pp. 1454-1456
ISSN:
0032-0943
Subject:
Aristolochia; medicinal plants; leaves; chemical constituents of plants; diterpenoids; lignans; quantitative analysis; plant extracts; medicinal properties; Chagas disease; disease control; human cell lines; trypanocides; leishmaniasis; Trypanosoma cruzi; dose response; cytotoxicity; hemolysis; chemical structure; secondary metabolites; Brazil
DOI:
10.1055/s-0029-1240952

38. Antitubercular constituents of Valeriana laxiflora

Author:
Gu, J.Q.; Wang, Y.; Fanzblau, S.G.; Montenegro, G.; Yang, D.; Timmermann, B.N.
Source:
Planta medica 2004 v.70 no.6 pp. 509-514
ISSN:
0032-0943
Subject:
Valerianaceae; herbaceous plants; medicinal plants; plant extracts; phytochemicals; lignans; antibacterial properties; Mycobacterium tuberculosis; tuberculosis; cell lines; cytotoxicity; chemical structure; spectral analysis; stereochemistry; Chile
DOI:
10.1055/s-2004-827149
PubMed:
15229801

39. Antitumor and antiinflammatory constituents fromceltis sinensis

Author:
Dae Keun Kim; Jong Pil Lim; Jin Wook Kim; Hee Wook Park; Jae Soon Eun
Source:
Archives of pharmacal research 2005 v.28 no.1 pp. 39-43
ISSN:
0253-6269
Subject:
anti-inflammatory agents; branches; chemical structure; chromatography; glycosides; lignans; rutin; silica gel; spectroscopy; steroids; triterpenoids
Abstract:
... Eight compounds were isolated from the methanolic extract of the twigs ofCeltis sinensis through repeated silica gel and Sephadex LH-20 column chromatography. Their chemical structures were elucidated as two triterpenoids, germanicol and epifriedelanol, two amide compounds, frans-N-caffeoyltyramine andcis-N-coumaroyltyramine, two lignan glycoside, pinoresinol glycoside and pinoresinol rutinoside, ...
DOI:
10.1007/BF02975133

40. Antiviral activity of lignans

Author:
Charlton, J.L.
Source:
Journal of natural products 1998 v.61 no.11 pp. 1447-1451
ISSN:
0163-3864
Subject:
lignans; roots; stems; bark; seeds; spectral analysis; chemical structure; antiviral agents; chemical constituents of plants; drugs
DOI:
10.1021/np980136z
PubMed:
9834179

41. Arisanschinins A-E, Lignans from Schisandra arisanensis Hay

Author:
Liu, Chin-Cheng; Abd El-Razek, Mohamed H.; Liaw, Chia-Ching; Cheng, Yuan-Bin; Chen, Chien-Kuang; Chien, Ching-Te; Kuo, Yao-Haur; Liou, Shorong-Shii; Shen, Ya-Ching
Source:
Planta medica 2010 v.76 no.14 pp. 1605-1610
ISSN:
0032-0943
Subject:
Schisandra; medicinal plants; aerial parts; chemical constituents of plants; lignans; quantitative analysis; chemical structure; plant extracts; medicinal properties; alpha-glucosidase; enzyme inhibitors; free radical scavengers; antioxidant activity; Taiwan
DOI:
10.1055/s-0029-1241014

42. Arylnaphthalene lactones: structures and pharmacological potentials

Author:
Soyoung Park; Seungsu Kim; Dongyun Shin
Source:
Phytochemistry reviews 2021 v.20 no.5 pp. 1033-1054
ISSN:
1568-7767
Subject:
antiretroviral agents; chemical structure; cytotoxicity; glycosylation; lactones; lignans; oxidation; plant biochemistry
Abstract:
... Natural arylnaphthalene lactones are representative lignans that are found in various dietary and medicinal plants. Their unique structural features and significant pharmacological activity have attracted considerable attention from both synthetic and medicinal chemists. Owing to their unique structural features such as relative rigid tetracyclic skeleton, structural diversity of more than five su ...
DOI:
10.1007/s11101-020-09735-z

43. Arylnaphthalene lignan glycosides and other constituents from Phyllanthus reticulatus

Author:
Jian-Xiong Ma; Ming-Sheng Lan; Shi-Jin Qu; Jun-Jie Tan; Hong-Feng Luo; Chang-Heng Tan; Da-Yuan Zhu
Source:
Journal of Asian natural products research 2012 v.14 no.11 pp. 1073-1077
ISSN:
1477-2213
Subject:
Phyllanthus; chemical structure; glycosides; lignans; spectroscopy
Abstract:
... Two new arylnaphthalene lignan glycosides, named reticulatusides A (1) and B (2), together with eight known compounds were isolated from the 95% EtOH extract of the whole plant of Phyllanthus reticulatus. The structures of the new compounds were elucidated by spectroscopic methods. ...
DOI:
10.1080/10286020.2012.712040

44. Arylnaphthalene lignans from in vitro cultures of Linum austriacum

Author:
Mohagheghzadeh, A.; Schmidt, T.J.; Alfermann, A.W.
Source:
Journal of natural products 2002 v.65 no.1 pp. 69-71
ISSN:
0163-3864
Subject:
Linum; callus; cell suspension culture; roots; cultured cells; naphthalene; lignans; spectral analysis; chemical structure; chemical constituents of plants; Iran
DOI:
10.1021/np0102814
PubMed:
11809070

45. Aryltetralol and aryltetralone lignans from Holostylis reniformis

Author:
Silva, T. da; Lopes, L.M.X.
Source:
Phytochemistry 2006 v.67 no.9 pp. 929-937
ISSN:
0031-9422
Subject:
Aristolochiaceae; medicinal plants; phytochemicals; lignans; chemical structure; spectral analysis; Brazil
Abstract:
... Aryltetralol and aryltetralone lignans were isolated from the hexane extracts of the roots of Holostylis reniformis. Their structures were determined by spectroscopic methods and chemical transformations. ...
DOI:
10.1016/j.phytochem.2006.02.007
PubMed:
16563445

46. Asymmetric Synthesis of Natural and Unnatural Dibenzylbutane Lignans from a Common Intermediate

Author:
Daniel E. Jeffries; Craig W. Lindsley
Source:
Journal of organic chemistry 2019 v.84 no.9 pp. 5974-5979
ISSN:
1520-6904
Subject:
chemical structure; chromatography; derivatization; lignans; organic chemistry; stereoselective synthesis
Abstract:
... Lignans are a structurally diverse class of natural products with extensive pharmacological effects. Here we report the syntheses of both natural and unnatural dibenzylbutane lignans from a common intermediate, which is prepared in five steps from known materials. Derivatization of this intermediate affords lignans featuring contiguous stereocenters in a high diastereomeric purity after chromatogr ...
DOI:
10.1021/acs.joc.9b00633

47. Asymmetric aldol approach to dibenzylbutyrolactone lignans: synthesis of (−)-(7′S)-hydroxymatairesinol and (−)-(7′S)-hydroxyarctigenin

Author:
Saumen Hajra; Abhisek Mandal; Sunit Hazra
Source:
Tetrahedron letters 2013 v.54 pp. 2171-2173
ISSN:
0040-4039
Subject:
alkylation; chemical structure; lignans
Abstract:
... A competent and general asymmetric synthesis of 7′-hydroxydibenzylbutyrolactone lignans such as (7′S)-hydroxymatairesinol and (7′S)-hydroxyarctigenin has been reported from N-succinyl-2-oxazolidinone in six steps where diastereoselective aldol reaction and stereoselective alkylation serve as the key steps. ...
DOI:
10.1016/j.tetlet.2013.02.044

48. Asymmetric glycolate alkylation approach towards total synthesis of 8-O.6′ and 8-O.4′-neolignans

Author:
Mukesh Gangar; Mangilal Chouhan; Sandeep Goyal; M. Harikrishnan; R Chandran; Avinash Ittuveetil; Vipin A. Nair
Source:
Tetrahedron letters 2016 v.57 no.52 pp. 5931-5934
ISSN:
0040-4039
Subject:
alkylation; chemical structure; lignans; stereoselectivity
Abstract:
... The glycolate alkylation approach for the total synthesis of 8-O.6′ and 8-O.4′-neolignans has been optimized affording the natural products with high overall yields and excellent stereoselectivity. The developed approach can be further utilized towards the synthesis of many natural and unnatural neolignans. This is the first approach for the synthesis of neolignans using asymmetric glycolate alkyl ...
DOI:
10.1016/j.tetlet.2016.11.087

49. Asymmetric synthesis of furofurans

Author:
Manat Pohmakotr; Chutima Kuhakarn; Vichai Reutrakul; Darunee Soorukram
Source:
Tetrahedron letters 2017 pp. -
ISSN:
0040-4039
Subject:
bioactive properties; chemical reactions; chemical structure; lignans; stereochemistry; stereoselectivity
Abstract:
... Furofurans are one of the largest sub-types of classical lignans which have been found to possess a broad range of important biological activities. Tremendous efforts have been directed to develop synthetic methodologies for the synthesis of furofurans, especially in a stereoselective manner, due to their interesting bioactivities associated with the structural and stereochemical complexity. This ...
DOI:
10.1016/j.tetlet.2017.11.011

50. Benzocyclohexane oxide derivatives and neolignans from Piper betle inhibit efflux-related resistance in Staphylococcus aureus

Author:
Zhong-Lin Sun; Jian-Ming He; Shuang-Ying Wang; Ru Ma; Proma Khondkar; Glenn W. Kaatz; Simon Gibbons; Qing Mu
Source:
RSC advances 2016 v.6 no.49 pp. 43518-43525
ISSN:
2046-2069
Subject:
Oriental traditional medicine; Piper betle; active ingredients; antibiotic resistance; bacteria; bioassays; chemical structure; circular dichroism spectroscopy; cytotoxicity; gel chromatography; growth models; herbs; lignans; methicillin; methicillin-resistant Staphylococcus aureus; norfloxacin; nuclear magnetic resonance spectroscopy; silica gel; synergism; therapeutics; transporters
Abstract:
... This research seeks to address the problem of methicillin-resistant Staphylococcus aureus (MRSA) by discovering synergistic antibacterial natural substances from traditional Chinese herbs using antibacterial bioassays. Six compounds, including three neolignans (−)-acuminatin (1), (−)-denudatin B (2), puberulin D (3), and three benzocyclohexane oxide derivatives ferrudiol (4), ellipeiopsol B (5) an ...
DOI:
10.1039/c6ra10199b

51. Bioactive Lignans from Peperomia duclouxii

Author:
Li, N.; Wu, J.L.; Hasegawa, T.; Sakai, J.; Bai, L.M.; Wang, L.Y.; Kakuta, S.; Furuya, Y.; Ogura, H.; Kataoka, T.
Source:
Journal of natural products 2007 v.70 no.4 pp. 544-548
ISSN:
0163-3864
Subject:
anti-inflammatory activity; humans; phytochemicals; cytotoxicity; multiple drug resistance; Peperomia; medicinal plants; cultured cells; lignans; spectral analysis; chemical structure; Oriental traditional medicine; anticarcinogenic activity; China
DOI:
10.1021/np0604533
PubMed:
17358082

52. Bioactive Lignans from Peperomia heyneana

Author:
Zhang, G.L.; Li, N.; Wang, Y.H.; Zheng, Y.T.; Zhang, Z.; Wang, M.W.
Source:
Journal of natural products 2007 v.70 no.4 pp. 662-664
ISSN:
0163-3864
Subject:
antiviral properties; Human immunodeficiency virus 1; phytochemicals; humans; Peperomia; medicinal plants; lignans; spectral analysis; chemical structure; China
DOI:
10.1021/np0605236
PubMed:
17291043

53. Bioactive Secolignans from Peperomia dindygulensis

Author:
Wu, J.L.; Li, N.; Hasegawa, T.; Sakai, J.; Mitsui, T.; Ogura, H.; Kataoka, T.; Oka, S.; Kiuchi, M.; Tomida, T.
Source:
Journal of natural products 2006 v.69 no.5 pp. 790-794
ISSN:
0163-3864
Subject:
humans; cell growth; cytotoxicity; Peperomia; plant extracts; cultured cells; lignans; spectral analysis; chemical constituents of plants; chemical structure; Oriental traditional medicine; anticarcinogenic activity; China
DOI:
10.1021/np0600447
PubMed:
16724842

54. Bioactive compounds from Peperomia pellucida

Author:
Xu, S.; Li, N.; Ning, M.M.; Zhou, C.H.; Yang, Q.R.; Wang, M.W.
Source:
Journal of natural products 2006 v.69 no.2 pp. 247-250
ISSN:
0163-3864
Subject:
Peperomia; medicinal plants; traditional medicine; lignans; chemical structure; spectral analysis; anticarcinogenic activity; cytotoxicity; humans; cultured cells; estrogens; China
DOI:
10.1021/np050457s
PubMed:
16499324

55. Bioactive constituents of the roots of Cynanchum atratum

Author:
Day, S.H.; Wang, J.P.; Won, S.J.; Lin, C.N.
Source:
Journal of natural products 2001 v.64 no.5 pp. 608-611
ISSN:
0163-3864
Subject:
Cynanchum; medicinal plants; roots; lignans; glycosides; spectral analysis; chemical structure; humans; cell lines; tumor necrosis factors; anti-inflammatory agents; chemical constituents of plants; China
DOI:
10.1021/np000428b
PubMed:
11374953

56. Bioactive dibenzylbutyrolactone and dibenzylbutanediol lignans from Peperomia duclouxii

Author:
Li, N.; Wu, J.L.; Hasegawa, T.; Sakai, J.; Wang, L.Y.; Kakuta, S.; Furuya, Y.; Tomida, A.; Tsuruo, T.; Ando, M.
Source:
Journal of natural products 2006 v.69 no.2 pp. 234-239
ISSN:
0163-3864
Subject:
Peperomia; medicinal plants; lactones; lignans; chemical structure; spectral analysis; cytotoxicity; anticarcinogenic activity; humans; cultured cells; China
DOI:
10.1021/np050417o
PubMed:
16499322

57. Bioactive norlignan glucosides from Curculigo capitulata

Author:
Chang, W.L.; Su, M.J.; Lee, S.S.
Source:
Journal of natural products 1997 v.60 no.2 pp. 76-80
ISSN:
0163-3864
Subject:
Curculigo; medicinal plants; rhizomes; lignans; glucosides; spectral analysis; chemical structure; epinephrine; heart rate; medicinal properties; chemical constituents of plants; Taiwan
DOI:
10.1021/np9604902

58. Bioactive tetrahydrofuran lignans from Peperomia dindygulensis

Author:
Wu, J.; Li, N.; Hasegawa, T.; Sakai, J.; Kakuta, S.; Tang, W.; Oka, S.; Kiuchi, M.; Ogura, H.; Kataoka, T.
Source:
Journal of natural products 2005 v.68 no.11 pp. 1656-1660
ISSN:
0163-3864
Subject:
traditional medicine; anti-inflammatory activity; cell growth; humans; phytochemicals; Peperomia; medicinal plants; plant extracts; furans; human health; cultured cells; lignans; spectral analysis; chemical structure; China
DOI:
10.1021/np050283e
PubMed:
16309318

59. Bioinspired Asymmetric Synthesis of (−)-Gymnothelignan V

Author:
Darunee Soorukram; Manat Pohmakotr; Chutima Kuhakarn; Vichai Reutrakul
Source:
Journal of organic chemistry 2018 v.83 no.7 pp. 4173-4179
ISSN:
1520-6904
Subject:
biochemical pathways; chemical reactions; chemical structure; lignans; organic chemistry; stereoselectivity
Abstract:
... A bioinspired asymmetric total synthesis of a structurally unique subtype of lignan, namely, (−)-gymnothelignan V, was achieved. The key synthetic sequences involved reduction of the eupomatilone skeleton leading to (−)-gymnothelignan J followed by the formation of the corresponding oxocarbenium ion and stereoselective intramolecular Friedel–Crafts reaction. Our synthetic approach provides the inf ...
DOI:
10.1021/acs.joc.8b00164

60. Bioinspired Total Synthesis of Gymnothelignan N

Author:
Li Huilin; Zhang Yuanyuan; Xie Xingang; Ma Haichen; Zhao Changgui; Zhao Gaoyuan; She Xuegong
Source:
Organic letters 2014 v.16 no.17 pp. 4440-4443
ISSN:
1523-7052
Subject:
biochemical pathways; chemical reactions; chemical structure; lignans; phenol
Abstract:
... Bioinspired total synthesis of gymnothelignan N was accomplished in 13 steps and 6.7% overall yield. The synthesis features a syn Evans aldol reaction, an intramolecular hydrogenative dehydration reaction, and a phenol oxidative dearomatization/Friedel–Crafts reaction, which provides a new plausible biosynthetic pathway for the gymnothelignans and other symbiotic members. Meanwhile, another tetrah ...
DOI:
10.1021/ol501960j

61. Biological activity and aryltetraline lignans of Linum persicum

Author:
Javidnia, K.; Miri, R.; Rezai, H.; Jafari, A.; Azarmehr, A.; Amirghofran, Z.
Source:
Pharmaceutical biology 2005 v.43 no.6 pp. 547-550
ISSN:
1388-0209
Subject:
Linum; medicinal plants; antibacterial properties; cytotoxicity; cytotoxins; shrimp; Artemia salina; anticarcinogenic activity; chemical structure; aerial parts; plant extracts; lignans; phytochemicals
DOI:
10.1080/13880200500220854

62. Biopreparation of an anti-inflammatory agent, diarctigenin, from arctiin isolated from Arctium lappa by Rhizoctonia solani AG-4

Author:
Ping-Chung Kuo; Zi-Yu Chen; Miao-Fan Chen
Source:
Tetrahedron letters 2013 v.54 pp. 6955-6958
ISSN:
0040-4039
Subject:
Arctium lappa; Thanatephorus cucumeris; anti-inflammatory activity; anti-inflammatory agents; biocatalysts; biotransformation; chemical reactions; chemical structure; enzymatic hydrolysis; high performance liquid chromatography; lignans; methanol; monitoring; pesticides; screening; sugars
Abstract:
... In the preliminary screening for the plant-derived pesticides against Rhizoctonia solani Kühn AG-4 (RS AG-4), the indicator compounds arctiin (1) and arctigenin (2) in methanol extracts of Arctium lappa L. were consumed and transformed to other compounds. Thus, in the present study RS AG-4 was used as a biocatalyst and the biotransformation of arctiin (1) was investigated. Conversion of arctiin (1 ...
DOI:
10.1016/j.tetlet.2013.10.057

63. Biosynthesis of (+)-syringaresinol inLiriodendron tulipifera I: feeding experiments withL-[U-14C]phenylalanine and [8-14C]sinapyl alcohol

Author:
Takeshi Katayama; Atsushi Ogaki
Source:
Journal of wood science 2001 v.47 no.1 pp. 41-47
ISSN:
1435-0211
Subject:
biosynthesis; isotope labeling; stems; chemical reactions; beta-glucosidase; chemical structure; Liriodendron tulipifera; lignans; resinols; phenylalanine; glucosides; leaves; Japan
Abstract:
... To clarify the biosynthesis of syringyl lignans and lignan formation by stereoselective coupling of monolignols, formation of (+)-syringaresinol and (+)-pinoresinol inLiriodendron tulipifera were investigated by means of feeding experiments. Following individual administration ofL-[U-¹⁴C]phenylalanine and [8-¹⁴C]sinapyl alcohol to excised shoots ofL. tulipifera and their subsequent metabolism for ...
DOI:
10.1007/BF00776644

64. Biosynthetic pathway to the cancer chemopreventive secoisolariciresinol diglucoside-hydroxymethl glutaryl ester-linked lignan oligomers in flax (Linum usitatissimum) seed. [Erratum: May 2002, v. 65 (5), p. 800.]

Author:
Ford, J.D.; Huang, K.S.; Wang, H.B.; Davin, L.B.; Lewis, N.G.
Source:
Journal of natural products 2001 v.64 no.11 pp. 1388-1397
ISSN:
0163-3864
Subject:
Linum usitatissimum; seeds; resinols; glucosides; lignans; glutaric acid; spectral analysis; chemical structure; antineoplastic agents; biosynthesis; chemical reactions; biochemical pathways; chemical constituents of plants
DOI:
10.1021/np010367x

65. Bisamides, lignans, triterpenes, and insecticidal cyclopenta[b]benzofurans from Aglaia species

Author:
Brader, G.; Vajrodaya, S.; Greger, H.; Bacher, M.; Kalchhauser, H.; Hofer, O.
Source:
Journal of natural products 1998 v.61 no.12 pp. 1482-1490
ISSN:
0163-3864
Subject:
Aglaia; leaves; stems; roots; bark; amides; lignans; triterpenoids; furans; spectral analysis; chemical structure; insecticidal properties; insect pests; Spodoptera littoralis; Lymantria dispar; insect control; chemical constituents of plants; Thailand
DOI:
10.1021/np9801965
PubMed:
9868148

66. Cardiovascular protective flavonolignans and flavonoids from Calamus quiquesetinervius

Author:
Chang, Chao-Lin; Wang, Guei-Jane; Zhang, Li-Jie; Tsai, Wen-Jen; Chen, Ru-Yin; Wu, Yang-Chang; Kuo, Yao-Haur
Source:
Phytochemistry 2010 v.71 no.2-3 pp. 271-279
ISSN:
0031-9422
Subject:
Calamus; medicinal plants; lignans; flavonoids; chemical structure; stereochemistry; spectral analysis; medicinal properties; antioxidant activity; vasodilation; platelet aggregation; rabbits; rats; oxidative stress; animal disease models; human health
Abstract:
... Tricin-type flavonolignans, (2S)-dihydrotricin 4'-O-(erythro-β-guaiacylglyceryl) ether, (2S)-dihydrotricin 4'-O-(threo-β-guaiacylglyceryl) ether, (2S)-dihydrotricin 4'-O-(threo-β-4-hydroxyphenylglyceryl) ether, tricin 4'-O-(erythro-β-4-hydroxyphenylglyceryl) ether, tricin 4'-O-(threo-β-4-hydroxylphenylglyceryl) ether, and (2S)-dihydrotricin 4'-O-(β-6"-methoxy-4"-oxo-chroman-3"-yloxy) ether namely ...
DOI:
10.1016/j.phytochem.2009.09.025
PubMed:
20006366

67. Chakyunglupulins A and B, two novel 4,8,8-trimethylcyclooct-2-enone derivatives from Barleria lupulina

Author:
Ki Hyun Kim; Jon Clardy; Donald Senger; Shugeng Cao
Source:
Tetrahedron letters 2015 v.56 no.21 pp. 2732-2734
ISSN:
0040-4039
Subject:
Barleria; aerial parts; chemical reactions; chemical structure; lignans; spectral analysis
Abstract:
... Two novel 4,8,8-trimethylcyclooct-2-enone derivatives, chakyunglupulins A and B, together with six known lignans were isolated from the aerial part of Barleria lupulina. The structures of new compounds were established by extensive spectroscopic data and HR-MS, and their absolute configurations were determined by a combination of NOE experiment and application of the modified Mosher’s method. ...
DOI:
10.1016/j.tetlet.2015.04.023
PubMed:
26240452
PubMed Central:
PMC4521596

68. Chemical Constituents, Antimicrobial and Antimalarial Activities of Zanthoxylum monophyllum

Author:
Rodriguez-Guzman, Raquel; Fulks, Laura C. Johansmann; Radwan, Mohamed M.; Burandt, Charles L.; Ross, Samir A.
Source:
Planta medica 2011 v.77 no.13 pp. 1542-1544
ISSN:
0032-0943
Subject:
Aspergillus fumigatus; Plasmodium falciparum; Staphylococcus aureus; Zanthoxylum; alkaloids; bark; chemical analysis; chemical composition; chemical structure; inhibitory concentration 50; leaves; lignans; spectroscopy
Abstract:
... From the leaves and bark of Zanthoxylum monophyllum, a new lignan, 3-methoxy-3′,4′-methylenedioxylignan-4,8,9,9′-tetraol (1), has been isolated along with 22 known compounds (2-23), fifteen of them reported for the first time from Z. monophyllum. Their chemical structures were elucidated using detailed spectroscopic studies and chemical analysis. All compounds were evaluated for antimicrobial and ...
DOI:
10.1055/s-0030-1270782
PubMed:
21341176

69. Chemical and thermal characteristics of lignins isolated from Siam weed stem by acetic acid and formic acid delignification

Author:
Zhao, Xuebing; Liu, Dehua
Source:
Industrial crops and products 2010 v.32 no.3 pp. 284-291
ISSN:
0926-6690
Subject:
thermogravimetry; Chromolaena odorata; formic acid; stems; glass transition temperature; activation energy; p-coumaric acid; differential scanning calorimetry; extraction; invasive species; molecular weight; phytochemicals; delignification; lignans; weeds; chemical structure; thermal properties; acetic acid; pyrolysis
Abstract:
... The stem of Siam weed, an invasive exotic plant, was delignified by Acetosolv and Milox processes. The lignin products, Acetosolv lignin (AL) and Milox lignin (ML), were characterized in order to investigate the chemical structures and thermal characteristics. It was found that the weed lignin was syringyl-guaiacyl (GS) type lignin. Both lignins showed similarity in elemental components, functiona ...
DOI:
10.1016/j.indcrop.2010.05.003

70. Chemical constituents from Cassytha filiformis II

Author:
Chang, F.R.; Chao, Y.C.; Teng, C.M.; Wu, Y.C.
Source:
Journal of natural products 1998 v.61 no.7 pp. 863-866
ISSN:
0163-3864
Subject:
bioassays; fractionation; alkaloids; lignans; medicinal properties; chemical structure; chemical constituents of plants; Cassytha filiformis; platelet aggregation; Taiwan
DOI:
10.1021/np970348g
PubMed:
9677264

71. Chemical constituents from Epimedium koreanum Nakai and their chemotaxonomic significance

Author:
Xiang Dong Su; Wei Li; Jin Yeul Ma; Young Ho Kim
Source:
Natural product research 2018 v.32 no.19 pp. 2347-2351
ISSN:
1478-6427
Subject:
Epimedium koreanum; aerial parts; chemical composition; chemical structure; chemotaxonomy; flavonoids; lignans; mass spectrometry; nuclear magnetic resonance spectroscopy; phenols
Abstract:
... In this study, 21 compounds were isolated from the aerial parts of Epimedium koreanum Nakai, including 6 phenols (1–5 and 10), 4 lignans (6–9) and 11 flavonoids (11–21). The chemical structures of those isolates were established after extensive one-and two-dimensional nuclear magnetic resonance and mass spectroscopy analyses. This is the first report of compounds 2, 3, 4 and 9 in E. koreanum and o ...
DOI:
10.1080/14786419.2017.1405412

72. Chemical constituents from Saussurea cordifolia

Author:
Li, Xu-Wen; Guo, Zi-Tao; Zhao, Yun; Zhao, Zheng; Hu, Jin-Feng
Source:
Phytochemistry 2010 v.71 no.5-6 pp. 682-687
ISSN:
0031-9422
Subject:
Saussurea; medicinal plants; chemical constituents of plants; acetylene; glycosides; lignans; phytochemicals; chemical structure; spectral analysis; stereochemistry; cytotoxicity; anticarcinogenic activity; human diseases; human health; China
Abstract:
... Thirty-six naturally occurring compounds, including four C10-acetylenic glycosides and a lignan, were isolated from the whole plants of Saussurea cordifolia. Their structures were elucidated by means of spectroscopic and chemical methods to be 4,6-decadiyne-1-O-β-d-apiofuranosyl-(1 leads to 6)-β-d-glucopyranoside (1), 4,6-decadiyne-1-O-α-l-rhamnopyranosyl-(1 leads to 6)-β-d-glucopyranoside (2), (8 ...
DOI:
10.1016/j.phytochem.2009.12.016
PubMed:
20181367

73. Chemical constituents from Solidago canadensis with hypolipidemic effects in HFD-fed hamsters

Author:
Ying Huang; Yan-Li Hao; Xiao-Yan Mai
Source:
Journal of Asian natural products research 2013 v.15 no.4 pp. 319-324
ISSN:
1477-2213
Subject:
Solidago canadensis; chemical composition; chemical structure; hamsters; high fat diet; lignans; lipemic effect; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... Two new compounds, 8-dehydroxymethylvisanol (1) and 9-O-[3-O-acetyl-β-d-glucopyranosyl]-4-hydroxy-cinnamic acid (4), together with two known lignans, visanol (2) and 9-aldehydevibsanol (3), were isolated from the 80% EtOH extract of Solidago canadensis. The structures of the two new compounds were elucidated on the basis of 1D, 2D NMR, and mass spectral analysis. All the lignans exhibited moderate ...
DOI:
10.1080/10286020.2012.753059

74. Chemical constituents from ethanol extract of Polyalthia rumphii branches and their cytotoxicity evaluation

Author:
Tianshan Wang; Xiaopeng Wu; Yanping Liu; Youping Luo; Xiang Li; Yujie Zhou; AiPing Yang; Zhengmeng Yan; Ling Ye; Siwei Chen; Jinshuai Fu; Xianzhi Jiao
Source:
Revista Brasileira de Farmacognosia 2018 v.28 no.2 pp. 235-238
ISSN:
0102-695X
Subject:
Polyalthia; alkaloids; antineoplastic activity; branches; chemical composition; chemical structure; cytotoxicity; ethanol; gossypol; human cell lines; humans; inhibitory concentration 50; lignans; neoplasm cells; spectroscopy
Abstract:
... Twelve known compounds, including eight alkaloids, three lignans and one gossypol derivative, were isolated from the branches of Polyalthia rumphii (Blume ex Hensch.) Merr., Annonaceae. The chemical structures were determined by spectroscopic methods and comparison with literature data. All the isolates were evaluated the cytotoxicity against three human cancer cell lines: Hela, MCF-7 and A549, th ...
DOI:
10.1016/j.bjp.2018.03.004

75. Chemical constituents from the leaves of Crataegus pinnatifida Bge

Author:
Wanchun Chu; Pinyi Gao; Lingzhi Li
Source:
Biochemical systematics and ecology 2019 v.86 pp. 103923
ISSN:
0305-1978
Subject:
Crataegus pinnatifida; carbon; chemical composition; chemical structure; chemotaxonomy; coumaric acids; flavonoids; leaves; lignans; nuclear magnetic resonance spectroscopy; spectral analysis; stable isotopes; triterpenoids
Abstract:
... The phytochemical investigations on the leaves of Crataegus pinnatifida led to the isolation of 20 compounds, including seven triterpenoids (1-7), three hydroxycinnamic acids (8-10), three lignans (11-13) and seven flavonoids (14-20). All chemical structures were established on the basis of NMR (1H NMR, 13C NMR) spectroscopic data. Meanwhile, compounds 3-12 are reported for the first time from Crat ...
DOI:
10.1016/j.bse.2019.103923

76. Chemical constituents isolated from the roots of Sanguisorba officinalis L. and their chemotaxonomic significance

Author:
Rongshen Wang; Jinfeng Sun; Chao Ye; Jiaming Wang; Tieqiang Zong; Wei Zhou; Gao Li
Source:
Biochemical systematics and ecology 2020 v.89 pp. 103999
ISSN:
0305-1978
Subject:
Sanguisorba officinalis; chemical composition; chemical structure; chemotaxonomy; flavonoids; glycosides; lignans; monoterpenoids; phenols; roots; spectral analysis; triterpenoids
Abstract:
... Phytochemical investigation of the roots of Sanguisorba officinalis L. led to the isolation of thirty-eight compounds, including seventeen triterpenoids (1–17), six monoterpenoid glycosides (18–23), six flavonoids (24–29), six phenols (30–35), two glycosides (36–37), and one lignan (38). The chemical structures of these compounds were elucidated on the basis of spectral data and by comparisons of ...
DOI:
10.1016/j.bse.2019.103999

77. Chemical constituents of the roots of Scorzonera divaricata and their chemotaxonomic significance

Author:
Xian-Hua Meng; Yong-Jin Yang; Yuan Gong; Ying Zhu
Source:
Biochemical systematics and ecology 2020 v.93 pp. 104135
ISSN:
0305-1978
Subject:
Scorzonera divaricata; benzene derivatives; caffeic acid; chemical composition; chemical structure; chemotaxonomy; electrospray ionization mass spectrometry; lignans; nuclear magnetic resonance spectroscopy; phenylpropanoids; phytochemicals; roots; scopoletin; sterols
Abstract:
... The phytochemical study of the roots of Scorzonera divaricata Turcz led to the isolation of 27 compounds, including eight sterols (1–8), one lignan (9), two cumarins (10, 11), five phenylpropanoids (12–16), six benzene derivatives (17–22), methyl-β-D-fructofuranoside (23), monolinolein (24), and three aliphatic acids (25–27). The structures of isolated compounds were identified using NMR and ESI-M ...
DOI:
10.1016/j.bse.2020.104135

78. Chemical constituents of the whole plant of Elsholtzia rugulosa

Author:
Bo Liu; An-Jun Deng; Jin-Qian Yu; Ai-Lin Liu; Guan-Hua Du; Hai-Lin Qin
Source:
Journal of Asian natural products research 2012 v.14 no.2 pp. 89-96
ISSN:
1477-2213
Subject:
Elsholtzia; X-ray diffraction; apigenin; chemical composition; chemical structure; glycosides; lignans; luteolin; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... A new lignan glycoside, 7α, 7′β-bis-(4-hydroxy-3-methoxyphenyl)-7,9′:7′,9-diepoxylignan-8αH,8′α-O-β-d-(2″,7′α-epoxy)-glucopyranoside, named elshrugulosain (1), has been isolated from the EtOH extract of Elsholtzia rugulosa, together with six known compounds, ( − )-bornyl (E)-3,4,5-trimethoxycinnamate, apigenin, luteolin, apigenin-7-O-β-d-glucopyranoside, luteolin-7-O-β-d-glucopyranoside, and luteo ...
DOI:
10.1080/10286020.2011.644714

79. Chemical investigation of the stem bark and seeds of Staudtia kamerunensis

Author:
Yankep, E.; Emakam, B.; Kapnang, H.; Bodo, B.; Fomum, Z.T.
Source:
Pharmaceutical biology 1999 v.37 no.2 pp. 155-157
ISSN:
1388-0209
Subject:
Myristicaceae; stems; bark; seeds; plant extracts; lignans; spectral analysis; chemical structure; chemical constituents of plants; Cameroon
DOI:
10.1076/phbi.37.2.155.6088

80. Chemo-profiling of some Turkish Galanthus L. (Amaryllidaceae) species and their anticholinesterase activity

Author:
Buket Bozkurt; Gulen Irem Kaya; Mustafa Ali Onur; Nehir Unver-Somer
Source:
South African journal of botany 2021 v.136 pp. 65-69
ISSN:
0254-6299
Subject:
Alzheimer disease; Galanthus; acetylcholinesterase; bioactive properties; bulbs; chemical composition; chemical structure; cholinesterase; cholinesterase inhibitors; indigenous species; isoquinoline alkaloids; lignans; ornamental value; plant extracts; research
Abstract:
... Amaryllidaceae family, consisting of economically important plants with ornamental value, is very well-known for its isoquinoline alkaloids with variable biological activities and chemical structures. Among these alkaloids, an effective acetylcholinesterase inhibitor galanthamine, is prescribed widely in the treatment of Alzheimer's disease. Plants of the Amaryllidaceae family are therefore, subje ...
DOI:
10.1016/j.sajb.2020.09.012

81. Coixlachryside A: A new lignan glycoside from the roots of Coix lachryma-jobi L. var. ma-yuen Stapf.

Author:
Seong Su Hong; Chun Whan Choi; Yun-Hyeok Choi; Joa Sub Oh
Source:
Phytochemistry letters 2016 v.17 pp. 152-157
ISSN:
1874-3900
Subject:
Coix lacryma-jobi; chemical structure; chromatography; circular dichroism spectroscopy; glycosides; lignans; nuclear magnetic resonance spectroscopy; roots; spectral analysis
Abstract:
... A new lignan glycoside, 1-[3,6-(4,4⿲-dihydroxy-3,3⿲-dimethoxy-δ-truxinyl)-β-fructofuranosyl]-α-glucopyranoside (1), named coixlachryside A, together with nine known simple phenolic compounds (3⿿11) were isolated from the roots of Coix lachryma-jobi var. ma-yuen using various chromatographic methods. Their chemical structures were determined based on the spectroscopic data interpretation, particula ...
DOI:
10.1016/j.phytol.2016.07.004

82. Comparative assessment of compositional components, antioxidant effects, and lignan extractions from Korean white and black sesame (Sesamum indicum L.) seeds for different crop years

Author:
Jin Hyo Kim; Woo Duck Seo; Seong Kyu Lee; Yong Bok Lee; Choon Hwa Park; Hyung Won Ryu; Jin Hwan Lee
Source:
Journal of functional foods 2014 v.7 pp. 495-505
ISSN:
1756-4646
Subject:
2,2-diphenyl-1-picrylhydrazyl; Sesamum indicum; acetonitrile; antioxidant activity; chemical structure; color; cultivars; lignans; nuclear magnetic resonance spectroscopy; oils; seeds; sesame seed; solvents
Abstract:
... The compositional components (lignan, protein, and oil) as well as antioxidant properties of white and black sesame seeds from different crop years were evaluated. Various solvent extracts of sesame seeds possessed two major peaks and their chemical structures were confirmed as sesamin (1) and sesamolin (2) using NMR spectroscopy and HPLC–DAD–ESI/MS technique. Moreover, their optimal extraction wa ...
DOI:
10.1016/j.jff.2014.01.006

83. Compounds from Kadsura heteroclita and related anti-HIV activity

Author:
Pu, J.X.; Yang, L.M.; Xiao, W.L.; Li, R.T.; Lei, C.; Gao, X.M.; Huang, S.X.; Li, S.H.; Zheng, Y.T.; Huang, H.
Source:
Phytochemistry 2008 v.69 no.5 pp. 1266-1272
ISSN:
0031-9422
Subject:
Kadsura; phytochemicals; triterpenoids; lactones; lignans; chemical structure; spectral analysis; stereochemistry; medicinal properties; antiviral properties; Human immunodeficiency virus 1
Abstract:
... Phytochemical investigation of the stems of Kadsura heteroclita led to isolation of 16 compounds, including the triterpenoid named longipedlactone J (2), and two dibenzocyclooctadiene type lignans named heteroclitin I and J (3, 4). Compounds 8-10, 14, and 15 were weakly active as anti-HIV agents, whereas compounds 6 and 12 exhibited moderate anti-HIV activity with EC50 values of 1.6 μg/mL, and 1.4 ...
DOI:
10.1016/j.phytochem.2007.11.019
PubMed:
18207206

84. Computationally Assisted Assignment of the Kadsuraols, a Class of Chemopreventive Agents for the Control of Liver Cancer

Author:
Xiaojuan Wang; Jiabao Liu; Pankaj Pandey; Frank R. Fronczek; Robert J. Doerksen; Jiabao Chen; Xinzhu Qi; Peicheng Zhang; Daneel Ferreira; Frederick A. Valeriote; Hua Sun; Shuai Li; Mark T. Hamann
Source:
Organic letters 2018 v.20 no.18 pp. 5559-5563
ISSN:
1523-7052
Subject:
Kadsura; X-ray diffraction; acetaminophen; carbon; chemical reactions; chemical structure; chemoprevention; circular dichroism spectroscopy; crystallography; cytotoxicity; hepatoprotective effect; lignans; nuclear magnetic resonance spectroscopy; roots
Abstract:
... Kadsuraols A–C (1–3), which are tetrahydrocyclobutaphenanthrofuranone-type lignans with a new carbon skeleton comprising a four-membered ring across C-1′–C-8, have been isolated from the roots of Kadsura longipedunculata. Their structures and absolute configurations were unambiguously determined using nuclear magnetic resonance, X-ray diffraction crystallography, DP4+ calculations, and computed an ...
DOI:
10.1021/acs.orglett.8b02207

85. Configurational analysis of cubebins and bicubebin from Aristolochia lagesiana and Aristolochia pubescens

Author:
Pascoli, I.C. de; Nascimento, I.R.; Lopes, L.M.X.
Source:
Phytochemistry 2006 v.67 no.7 pp. 735-742
ISSN:
0031-9422
Subject:
lignans; spectral analysis; chemical constituents of plants; chemical structure; stereochemistry; Aristolochia; Brazil
Abstract:
... (8S,8'R,9S)-, (8R,8'R,9R)-, and (8R,8'R,9S)-cubebins, together with (8R,8'R,8"R,8'''R,9R,9"S)-bicubebin, were isolated from Aristolochia lagesiana and Aristolochia pubescens. Their structures were determined by spectroscopic methods, including 1H and 13C NMR spectroscopy at low temperatures, and by chemical transformations. ...
DOI:
10.1016/j.phytochem.2006.01.019
PubMed:
16500688

86. Constituents of Boronia pinnata

Author:
Ito, C.; Itoigawa, M.; Otsuka, T.; Tokuda, H.; Nishino, H.; Furukawa, H.
Source:
Journal of natural products 2000 v.63 no.10 pp. 1344-1348
ISSN:
0163-3864
Subject:
Boronia; phenylpropanoids; antiviral agents; medicinal plants; chemical structure; antineoplastic agents; lignans; spectral analysis; chemical constituents of plants; roots; quinolones; stereochemistry; Human gammaherpesvirus 4
DOI:
10.1021/np0000318
PubMed:
11076549

87. Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2

Author:
Jang, D.S.; Cuendet, M.; Su, B.N.; Totura, S.; Riswan, S.; Fong, H.H.S.; Pezzuto, J.M.; Kinghorn, A.D.
Source:
Planta medica 2004 v.70 no.10 pp. 893-896
ISSN:
0032-0943
Subject:
phytochemicals; plant extracts; enzyme inhibitors; lignans; Hernandia; prostaglandin synthase; spectral analysis; chemical structure; stereochemistry; Indonesia
DOI:
10.1055/s-2004-832612
PubMed:
15490314

88. Constituents of the twigs of Hernandia ovigera that inhibit the transformation of JB6 murine epidermal cells

Author:
Gu, J.Q.; Park, E.J.; Totura, S.; Riswan, S.; Fong, H.H.S.; Pezzuto, J.M.; Kinghorn, A.D.
Source:
Journal of natural products 2002 v.65 no.7 pp. 1065-1068
ISSN:
0163-3864
Subject:
branches; lignans; spectral analysis; chemical structure; bioassays; cell differentiation; antineoplastic agents; disease prevention; chemical constituents of plants; Indonesia
DOI:
10.1021/np020042w
PubMed:
12141878

89. Contribution of oak lignans to wine taste: chemical identification, sensory characterization and quantification

Author:
Axel Marchal; Blandine N. Cretin; Lauriane Sindt; Pierre Waffo-Téguo; Denis Dubourdieu
Source:
Tetrahedron 2015 v.71 pp. 3148-3156
ISSN:
0040-4020
Subject:
Quercus petraea; bitterness; chemical reactions; chemical structure; detection limit; heartwood; lignans; quantitative analysis; sensory evaluation; taste; wines; wood
Abstract:
... The modification of wine taste during oak ageing is due to the release of non-volatile compounds from wood. Among these molecules, some lignans have been previously described as exhibiting bitterness. However, the lack of knowledge concerning this class of compounds in oak wood led us to explore both their structural diversity and their sensory properties. Nine lignans were isolated from extracts ...
DOI:
10.1016/j.tet.2014.07.090

90. Coumarins and Lignans from Zanthoxylum schinifolium and Their Anticancer Activities

Author:
Li Wei; Sun Ya Nan; Yan Xi Tao; Yang Seo Young; Kim Eun-Ji; Kang Hee Kyoung; Kim Young Ho
Source:
Journal of agricultural and food chemistry 2013 v.61 no.45 pp. 10730-10740
ISSN:
1520-5118
Subject:
Oriental traditional medicine; Zanthoxylum schinifolium; anticarcinogenic activity; apoptosis; chemical structure; colorectal neoplasms; common cold; coumarins; diarrhea; humans; inhibitory concentration 50; jaundice; leaves; leukemia; lignans; methanol; mitogen-activated protein kinase; nuclear magnetic resonance spectroscopy; pericarp; prostatic neoplasms; shrubs; stems; stomach
Abstract:
... Zanthoxylum schinifolium is an aromatic shrub, and its pericarp and leaves are widely used in culinary applications in East Asian countries. It has also long been used in traditional Oriental medicine for treating the common cold, stomach ache, diarrhea, and jaundice. In this study, we identified two new compounds, zanthoxyloside (1) and schinifolisatin A (13), along with 23 known coumarins (2–12) ...
DOI:
10.1021/jf403479c
PubMed:
24144361

91. Coumarins with monoamine oxidase inhibitory activity and antioxidative coumarino-lignans from Hibiscus syriacus

Author:
Yun, B.S.; Lee, I.K.; Ryoo, I.J.; Yoo, I.D.
Source:
Journal of natural products 2001 v.64 no.9 pp. 1238-1240
ISSN:
0163-3864
Subject:
Hibiscus syriacus; antidepressants; scopoletin; medicinal plants; neurotransmitters; enzyme inhibitors; lignans; spectral analysis; antioxidants; chemical constituents of plants; amine oxidase (flavin-containing); bark; roots; chemical structure; South Korea
DOI:
10.1021/np0100946
PubMed:
11575966

92. Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata

Author:
Ohse, T.; Ohba, S.; Yamamoto, T.; Koyano, T.; Umezawa, K.
Source:
Journal of natural products 1996 v.59 no.7 pp. 650-652
ISSN:
0163-3864
Subject:
protein synthesis; medicinal plants; furans; antineoplastic agents; lignans; growth retardation; spectral analysis; chemical constituents of plants; cell lines; Aglaia; chemical structure; leaves; Thailand
DOI:
10.1021/np960346g
PubMed:
8759160

93. Cytotoxic Lignans from the Stem Bark of Magnolia officinalis

Author:
Youn, U.J.; Chen, Q.C.; Jin, W.Y.; Lee, I.S.; Kim, H.J.; Lee, J.P.; Chang, M.J.; Min, B.S.; Bae, K.H.
Source:
Journal of natural products 2007 v.70 no.10 pp. 1687-1689
ISSN:
0163-3864
Subject:
Magnolia; medicinal plants; Oriental traditional medicine; lignans; chemical structure; spectral analysis; stereochemistry; cytotoxicity; anticarcinogenic activity; cultured cells; humans
DOI:
10.1021/np070388c
PubMed:
17918910

94. Cytotoxic and HIF-1α Inhibitory Compounds from Crossosoma bigelovii

Author:
Klausmeyer, Paul; Zhou, Qin; Scudiero, Dominic A.; Uranchimeg, Badarch; Melillo, Giovanni; Cardellina, John H. II; Shoemaker, Robert H.; Chang, Ching-jer; McCloud, Thomas G.
Source:
Journal of natural products 2009 v.72 no.5 pp. 805-812
ISSN:
0163-3864
Subject:
transcription factors; cardenolides; fractionation; cytotoxicity; Magnoliopsida; plant extracts; chemical structure; secondary metabolites; indole alkaloids; lignans; resinols; glycosides; matairesinol
DOI:
10.1021/np8006342

95. Cytotoxic and genotoxic butanolides and lignans from Aiouea trinervis

Author:
Garcez, F.R.; Garcez, W.S.; Martins, M.; Matos, M.F.C.; Guterres, Z.R.; Mantovani, M.S.; Misu, C.K.; Nakashita, S.T.
Source:
Planta medica 2005 v.71 no.10 pp. 923-927
ISSN:
0032-0943
Subject:
DNA damage; lactones; humans; phytochemicals; cytotoxicity; Lauraceae; furans; plant extracts; human health; cultured cells; lignans; animal physiology; spectral analysis; genotoxicity; chemical structure; anticarcinogenic activity
DOI:
10.1055/s-2005-871251
PubMed:
16254823

96. Cytotoxic arylnaphthalene lignans from a Vietnamese Acanthaceae, Justicia patentiflora

Author:
Susplugas, S.; Nguyen Van Hung; Bignon, J.; Thoison, O.; Kruczynski, A.; Sevenet, T.; Gueritte, F.
Source:
Journal of natural products 2005 v.68 no.5 pp. 734-738
ISSN:
0163-3864
Subject:
Justicia; plant extracts; phytochemicals; lignans; chemical structure; spectral analysis; cytotoxicity; anticarcinogenic activity; humans; cultured cells; Vietnam
DOI:
10.1021/np050028u
PubMed:
15921419

97. Cytotoxic constituents of Achillea clavennae from Montenegro

Author:
Trifunovic, S.; Vajs, V.; Juranic, Z.; Zizak, Z.; Tesevic, V.; Macura, S.; Milosavljevic, S.
Source:
Phytochemistry 2006 v.67 no.9 pp. 887-893
ISSN:
0031-9422
Subject:
humans; cytotoxicity; medicinal plants; flavonols; guaianolides; cultured cells; Achillea clavennae; lignans; spectral analysis; coumarin; cell proliferation; chemical structure; anticarcinogenic activity; Montenegro
Abstract:
... Examination of the aerial parts of Achillea clavennae afforded eight guaianolides (1-8), three bisabolenes (9-11), four flavonols (12-15), sesamin (lignan) and isofraxidin (coumarin). The structures of the new compounds (2, 4, 5, 7 and 10) were determined by spectroscopic methods. The antiproliferative action of 2, 8, 9 and 12 were tested to HeLa, K562 and Fem-X human cancer cell lines. Guaianolid ...
DOI:
10.1016/j.phytochem.2006.02.026
PubMed:
16616262

98. Cytotoxic lignans of justicia ciliata

Author:
Day, S.H.; Chiu, N.Y.; Won, S.J.; Lin, C.N.
Source:
Journal of natural products 1999 v.62 no.7 pp. 1056-1058
ISSN:
0163-3864
Subject:
Justicia; medicinal plants; lignans; spectral analysis; chemical structure; antineoplastic agents; humans; cell lines; chemical constituents of plants; Taiwan
DOI:
10.1021/np9900167
PubMed:
10425143

99. C₁₈ Dibenzocyclooctadiene Lignans from Kadsura philippinensis

Author:
Shen, Y.C.; Liaw, C.C.; Cheng, Y.B.; Ahmed, A.F.; Lai, M.C.; Liou, S.S.; Wu, T.S.; Kuo, Y.H.; Lin, Y.C.
Source:
Journal of natural products 2006 v.69 no.6 pp. 963-966
ISSN:
0163-3864
Subject:
humans; phytochemicals; cytotoxicity; medicinal plants; free radical scavengers; cultured cells; lignans; spectral analysis; Kadsura; antioxidant activity; chemical structure; Oriental traditional medicine; anticarcinogenic activity; Taiwan
DOI:
10.1021/np058134j

100. DNA strand-scission by phloroglucinols and lignans from heartwood of Garcinia subelliptica Merr. and Justicia plants

Author:
Lu, Y.H.; Wei, B.L.; Ko, H.H.; Lin, C.N.
Source:
Phytochemistry 2008 v.69 no.1 pp. 225-233
ISSN:
0031-9422
Subject:
DNA damage; Garcinia subelliptica; phenols; lignans; spectral analysis; heartwood; Justicia; chemical structure; stereochemistry; Taiwan
Abstract:
... Five 2,4,6-prenylated phloroglucinols, garcinielliptones HA (1), HB (2), HC (3), HD (4) and HE (5), were isolated from the heartwood of Garcinia subelliptica Merr. Their structures, including relative configurations, were elucidated by means of spectroscopic data analysis. The ability of phloroglucinols, 1-5 and lignans, tuberculatin (8), justicidin A (9), procumbenoside A (10) and ciliatosides A ...
DOI:
10.1016/j.phytochem.2007.06.026
PubMed:
17686498