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- Author:
- Buket Bozkurt; Gulen Irem Kaya; Mustafa Ali Onur; Nehir Unver-Somer
- Source:
- South African journal of botany 2021 v.136 pp. 65-69
- ISSN:
- 0254-6299
- Subject:
- Alzheimer disease; Galanthus; acetylcholinesterase; bioactive properties; bulbs; chemical composition; chemical structure; cholinesterase; cholinesterase inhibitors; indigenous species; isoquinoline alkaloids; lignans; ornamental value; plant extracts; research
- Abstract:
- ... Amaryllidaceae family, consisting of economically important plants with ornamental value, is very well-known for its isoquinoline alkaloids with variable biological activities and chemical structures. Among these alkaloids, an effective acetylcholinesterase inhibitor galanthamine, is prescribed widely in the treatment of Alzheimer's disease. Plants of the Amaryllidaceae family are therefore, subje ...
- DOI:
- 10.1016/j.sajb.2020.09.012
- https://doi.org/10.1016/j.sajb.2020.09.012
- Author:
- Kai Yang; Tian-Rui Xu; Yan-Hong Fu; Ming Cai; Qi-Le Xia; Rong-Fa Guan; Xian-Guo Zou; Pei-Long Sun
- Source:
- Food research international 2021 v.139 pp. 109907
- ISSN:
- 0963-9969
- Subject:
- Fourier transform infrared spectroscopy; amino acid composition; chemical structure; food research; lignans; nutritive value; oil crops; sesame cake; solubility; thermal stability; ultrasonics
- Abstract:
- ... Sesame is an oil crop with high nutritional value. Protein is one of the main ingredients of sesame, however research on protein of cold-pressed sesame cake is limited. This study aimed to investigate the effects of ultrasonic pre-treatment (UPT) on physicochemical properties of proteins (yield, solubility, amino acid composition, surface properties, structural and thermal stability) extracted fro ...
- DOI:
- 10.1016/j.foodres.2020.109907
- https://doi.org/10.1016/j.foodres.2020.109907
- Author:
- Soyoung Park; Seungsu Kim; Dongyun Shin
- Source:
- Phytochemistry reviews 2021 v.20 no.5 pp. 1033-1054
- ISSN:
- 1568-7767
- Subject:
- antiretroviral agents; chemical structure; cytotoxicity; glycosylation; lactones; lignans; oxidation; plant biochemistry
- Abstract:
- ... Natural arylnaphthalene lactones are representative lignans that are found in various dietary and medicinal plants. Their unique structural features and significant pharmacological activity have attracted considerable attention from both synthetic and medicinal chemists. Owing to their unique structural features such as relative rigid tetracyclic skeleton, structural diversity of more than five su ...
- DOI:
- 10.1007/s11101-020-09735-z
- https://doi.org/10.1007/s11101-020-09735-z
4. Chemical constituents of the roots of Scorzonera divaricata and their chemotaxonomic significance
- Author:
- Xian-Hua Meng; Yong-Jin Yang; Yuan Gong; Ying Zhu
- Source:
- Biochemical systematics and ecology 2020 v.93 pp. 104135
- ISSN:
- 0305-1978
- Subject:
- Scorzonera divaricata; benzene derivatives; caffeic acid; chemical composition; chemical structure; chemotaxonomy; electrospray ionization mass spectrometry; lignans; nuclear magnetic resonance spectroscopy; phenylpropanoids; phytochemicals; roots; scopoletin; sterols
- Abstract:
- ... The phytochemical study of the roots of Scorzonera divaricata Turcz led to the isolation of 27 compounds, including eight sterols (1–8), one lignan (9), two cumarins (10, 11), five phenylpropanoids (12–16), six benzene derivatives (17–22), methyl-β-D-fructofuranoside (23), monolinolein (24), and three aliphatic acids (25–27). The structures of isolated compounds were identified using NMR and ESI-M ...
- DOI:
- 10.1016/j.bse.2020.104135
- https://doi.org/10.1016/j.bse.2020.104135
- Author:
- Weichen Xiong; Yanfang Yang; Yiyi Xiong; Bo Liu; Zhoutao Xie; Hezhen Wu
- Source:
- Chemistry of natural compounds 2020 v.56 no.1 pp. 50-52
- ISSN:
- 0009-3130
- Subject:
- Justicia procumbens; chemical structure; lignans; spectroscopy
- Abstract:
- ... A new neolignan, named (7′S,8′R)-5,3′-dimethoxy-4,4′,9′-trihydroxy-2-8′,9-O-7′-neolignan (1), along with two known compounds, secoisolariciresinol (2) and lariciresinol (3), was isolated from the whole plant of Justicia procumbens L. The structure of 1 was established by spectroscopic methods, and the absolute configuration was determined using circular dichroic (CD) spectra. ...
- DOI:
- 10.1007/s10600-020-02941-3
- https://doi.org/10.1007/s10600-020-02941-3
- Author:
- Dunja Šamec; Erna Karalija; Ivana Šola; Valerija Vujčić Bok; Branka Salopek-Sondi
- Source:
- Plants 2021 v.10 no.1 pp. -
- ISSN:
- 2223-7747
- Subject:
- abiotic stress; bioactive properties; biodiversity; chemical structure; crop production; drought; flavonoids; heavy metals; light; lignans; metabolites; phenolic acids; plant growth; polymerization; polyphenols; stilbenoids; stress response; temperature
- Abstract:
- ... Abiotic stressors such as extreme temperatures, drought, flood, light, salt, and heavy metals alter biological diversity and crop production worldwide. Therefore, it is important to know the mechanisms by which plants cope with stress conditions. Polyphenols, which are the largest group of plant-specialized metabolites, are generally recognized as molecules involved in stress protection in plants. ...
- DOI:
- 10.3390/plants10010118
- https://doi.org/10.3390/plants10010118
- Author:
- Rui Zhan; Dashan Li; Yuan-Lie Liu; Xiao-Yan Xie; Lei Chen; Li-Dong Shao; Wen-Jing Wang; Ye-Gao Chen
- Source:
- Tetrahedron 2020 v.76 no.40 pp. 131494
- ISSN:
- 0040-4020
- Subject:
- X-ray diffraction; acetone; bioactive properties; bioassays; biomimetic synthesis; branches; chemical reactions; chemical structure; circular dichroism spectroscopy; crystallography; enzyme inhibition; inducible nitric oxide synthase; inhibitory concentration 50; leaves; lignans; nitric oxide; phytochemicals; spectral analysis
- Abstract:
- ... Bioactivity-guided phytochemical investigation on 70% aqueous acetone extracts of the twigs and leaves of Horsfieldia kingii led to the isolation of two novel cyclic diarylpropanes (1 and 2) bearing a 2,3-dihydro-1H-indene core, one new diarylpropane (3), six known diarylpropanes (4–9), one flavanol (10), and seven lignans (11–17). Their structures were determined by extensive spectroscopic analys ...
- DOI:
- 10.1016/j.tet.2020.131494
- https://doi.org/10.1016/j.tet.2020.131494
- Author:
- Ming-Zao Zhao; Yi Shen; Wei Xu; Ying-Zhi Chen; Chao-Jiang Xiao; Bei Jiang
- Source:
- Journal of Asian natural products research 2020 v.22 no.6 pp. 594-600
- ISSN:
- 1477-2213
- Subject:
- Actinomyces viscosus; Astragalus; Candida albicans; Escherichia coli; Proteus vulgaris; Pseudomonas aeruginosa; Salmonella Typhi; Shigella dysenteriae; Staphylococcus aureus; Streptococcus mutans; antibacterial properties; antifungal properties; chemical structure; glycosides; lignans; methanol; nuclear magnetic resonance spectroscopy; plant extracts; roots; spectral analysis
- Abstract:
- ... A new lignan glycoside, astrayunoside A (1), along with eight known compounds (2–9), were obtained from the methanol extract of roots of Astragalus yunnanensis. All the compounds were obtained from A. yunnanensis for the first time. Their structures were elucidated by extensive spectroscopic analysis (1D and 2D-NMR, MS, UV, CD, and IR). The weak antibacterial activities of the crude extracts of A. ...
- DOI:
- 10.1080/10286020.2019.1607840
- https://doi.org/10.1080/10286020.2019.1607840
- Author:
- Mengyue Wang; Lili Wu; Hao Zhang; Dun Zhu Ci Ren; Tonghua Liu; Xiaobo Li
- Source:
- Chemistry of natural compounds 2019 v.55 no.5 pp. 839-842
- ISSN:
- 0009-3130
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Urtica; antioxidants; chemical structure; flavonoids; flowers; lignans; median effective concentration; phenolic acids; spectral analysis
- Abstract:
- ... Eleven compounds (1–11), including two new compounds (1, 2), were isolated from the antioxidant portion of the alcoholic extract of Urtica fissa flowers. Their chemical structures were elucidated from extensive spectroscopic analysis. The results of activity evaluation indicated that some compounds of phenolic acids (3, 4), flavonoids (7, 9, 10), and lignans (1, 6) possess significant activities o ...
- DOI:
- 10.1007/s10600-019-02827-z
- https://doi.org/10.1007/s10600-019-02827-z
- Author:
- Wanchun Chu; Pinyi Gao; Lingzhi Li
- Source:
- Biochemical systematics and ecology 2019 v.86 pp. 103923
- ISSN:
- 0305-1978
- Subject:
- Crataegus pinnatifida; carbon; chemical composition; chemical structure; chemotaxonomy; coumaric acids; flavonoids; leaves; lignans; nuclear magnetic resonance spectroscopy; spectral analysis; stable isotopes; triterpenoids
- Abstract:
- ... The phytochemical investigations on the leaves of Crataegus pinnatifida led to the isolation of 20 compounds, including seven triterpenoids (1-7), three hydroxycinnamic acids (8-10), three lignans (11-13) and seven flavonoids (14-20). All chemical structures were established on the basis of NMR (1H NMR, 13C NMR) spectroscopic data. Meanwhile, compounds 3-12 are reported for the first time from Crat ...
- DOI:
- 10.1016/j.bse.2019.103923
- https://doi.org/10.1016/j.bse.2019.103923
- Author:
- Rongshen Wang; Jinfeng Sun; Chao Ye; Jiaming Wang; Tieqiang Zong; Wei Zhou; Gao Li
- Source:
- Biochemical systematics and ecology 2020 v.89 pp. 103999
- ISSN:
- 0305-1978
- Subject:
- Sanguisorba officinalis; chemical composition; chemical structure; chemotaxonomy; flavonoids; glycosides; lignans; monoterpenoids; phenols; roots; spectral analysis; triterpenoids
- Abstract:
- ... Phytochemical investigation of the roots of Sanguisorba officinalis L. led to the isolation of thirty-eight compounds, including seventeen triterpenoids (1–17), six monoterpenoid glycosides (18–23), six flavonoids (24–29), six phenols (30–35), two glycosides (36–37), and one lignan (38). The chemical structures of these compounds were elucidated on the basis of spectral data and by comparisons of ...
- DOI:
- 10.1016/j.bse.2019.103999
- https://doi.org/10.1016/j.bse.2019.103999
- Author:
- Eiichiro Ono; Toshiyuki Waki; Daiki Oikawa; Jun Murata; Akira Shiraishi; Hiromi Toyonaga; Masako Kato; Naoki Ogata; Seiji Takahashi; Masa‐atsu Yamaguchi; Manabu Horikawa; Toru Nakayama
- Source:
- plant journal 2020 v.101 no.5 pp. 1221-1233
- ISSN:
- 0960-7412
- Subject:
- Sesamum indicum; biochemical pathways; biosynthesis; catalytic activity; chemical structure; glucosylation; glucosyltransferases; hydrophobicity; lignans; metabolites; mutants; phylogeny; seeds; sugars; two hybrid system techniques; water solubility
- Abstract:
- ... Sesame (Sesamum indicum) seeds contain a large number of lignans, phenylpropanoid‐related plant specialized metabolites. (+)‐Sesamin and (+)‐sesamolin are major hydrophobic lignans, whereas (+)‐sesaminol primarily accumulates as a water‐soluble sesaminol triglucoside (STG) with a sugar chain branched via β1→2 and β1→6‐O‐glucosidic linkages [i.e. (+)‐sesaminol 2‐O‐β‐d‐glucosyl‐(1→2)‐O‐β‐d‐glucoside ...
- DOI:
- 10.1111/tpj.14586
- https://doi.org/10.1111/tpj.14586
- Author:
- Yeong-Geun Lee; Kyeong-Hwa Seo; Jung Eun Gwag; Hyoung-Geun Kim; Jung-Hwan Ko; Dae Young Lee; Nam-In Baek
- Source:
- Chemistry of natural compounds 2019 v.55 no.3 pp. 432-434
- ISSN:
- 0009-3130
- Subject:
- Forsythia viridissima var. koreana; chemical structure; flowers; lignans
- Abstract:
- ... A new lignan (1) was isolated from the flowers of Forsythia koreana along with one known lignan, 4,4′-di-O-β-D-glucosylpinoresinol (2). The molecular structures were determined using spectral methods. These compounds were isolated from F. koreana flowers for the first time. ...
- DOI:
- 10.1007/s10600-019-02707-6
- https://doi.org/10.1007/s10600-019-02707-6
- Author:
- Padam Kumar; Kapil Dev; Khushbu Sharma; Mahendra Sahai; Rakesh Maurya
- Source:
- Natural product research 2019 v.33 no.2 pp. 233-238
- ISSN:
- 1478-6427
- Subject:
- Cissus quadrangularis; chemical constituents of plants; chemical structure; glycosides; lignans; mass spectrometry; nuclear magnetic resonance spectroscopy; spectral analysis; stems
- Abstract:
- ... Phytochemical investigation of Cissus quadrangularis stems led to the isolation of one new phenolic glycoside (1) and two new lignan glycosides (7 & 8) along with twelve known compounds (2–6 & 9–15). Their chemical structures were determined on the basis of extensive spectroscopic analysis using 1D, 2D NMR, and mass spectrometric analysis. Among the known compounds, 4–6, 9 and 12 were isolated for ...
- DOI:
- 10.1080/14786419.2018.1443099
- https://doi.org/10.1080/14786419.2018.1443099
- Author:
- C. Emir; A. Emir; B. Bozkurt; N.U. Somer
- Source:
- South African journal of botany 2019 v.121 pp. 63-67
- ISSN:
- 0254-6299
- Subject:
- Galanthus; acetylcholinesterase; chemical constituents of plants; chemical structure; cholinesterase; enzyme activity; enzyme inhibition; hordenine; lignans; metabolites; niacin; terpenoids; Turkey (country)
- Abstract:
- ... Phytochemical studies on Galanthus alpinus Sosn. var. alpinus from Turkey resulted in the isolation of 11 metabolites including, 1 terpenoid; (+)-blumenol A 1, 2 lignans; pinoresinol 2 and epipinoresinol 3, and 8 other compounds; (+)-homolycorine 4, (+)-8-O-demethylhomolycorine 5, arolycoricidine 6, N-Trans-feruloyltyramine 7, (−)-lycorine 8, nicotinic acid 9, O-methylnorbelladine 10 and hordenine ...
- DOI:
- 10.1016/j.sajb.2018.10.021
- https://doi.org/10.1016/j.sajb.2018.10.021
- Author:
- James M. Wood; Eufrânio N. da Silva Júnior; John F. Bower
- Source:
- Organic letters 2019 v.22 no.1 pp. 265-269
- ISSN:
- 1523-7052
- Subject:
- benzoquinones; catalytic activity; chemical structure; cycloaddition reactions; lignans; naphthoquinones; polyketides; rhodium
- Abstract:
- ... The first examples of Rh-catalyzed [2 + 2 + 2] cycloadditions between diynes and benzoquinones are described. The method enables de novo and step-economical access to challenging naphthoquinones that are of relevance to lignan and type II polyketide synthesis. The value of the chemistry is demonstrated by a short total synthesis of justicidone. ...
- DOI:
- 10.1021/acs.orglett.9b04266
- https://doi.org/10.1021/acs.orglett.9b04266
- Author:
- Yi Zhou; Mei Jin; Chunshi Jin; Chao Ye; Jiaming Wang; Jinfeng Sun; Cheng-Xi Wei; Wei Zhou; Gao Li
- Source:
- Natural product research 2020 v.34 no.2 pp. 225-232
- ISSN:
- 1478-6427
- Subject:
- Amaranthaceae; anti-inflammatory activity; caffeic acid; chemical structure; ethanol; interleukin-6; lignans; metabolites; nitric oxide; nuclear magnetic resonance spectroscopy; tumor necrosis factor-alpha
- Abstract:
- ... One new aryldihydronaphthalene-type lignan (1) together with eight known lignans (2-4, 7–11) as well as two caffeic-acid dimers (5, 6) were isolated from an ethanol extract of the whole plant of Corispermum mongolicum Iljin (Chenopodiaceae). The chemical structures of these compounds were determined from 1D and 2D NMR and HR-ESI-MS spectra, and results were compared with data from the literature. ...
- DOI:
- 10.1080/14786419.2018.1527835
- https://doi.org/10.1080/14786419.2018.1527835
- Author:
- Xin-Ya XU; Dong-Ying WANG; Chuen-Fai KU; Yang ZHAO; Han CHENG; Kang-Lun LIU; Li-Jun RONG; Hong-Jie ZHANG
- Source:
- Chinese journal of natural medicines 2019 v.17 no.12 pp. 945-952
- ISSN:
- 1875-5364
- Subject:
- Human immunodeficiency virus 1; Justicia procumbens; Oriental traditional medicine; acetates; antiretroviral properties; chemical structure; cytotoxicity; inhibitory concentration 50; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
- Abstract:
- ... Twenty-one lignans including three new ones (1, 2 and 13) were isolated from Justicia procumbens. The chemical structures of the new lignans were determined by spectroscopic means including 1D and 2D NMR analysis. These compounds were evaluated for their cytotoxic and anti-HIV activities. The new secoisolariciresinol dimethyl ether acetate (13) exhibited anti-HIV-1 activity with an IC50 value of 5 ...
- DOI:
- 10.1016/S1875-5364(19)30117-7
- https://doi.org/10.1016/S1875-5364(19)30117-7
- Author:
- Daniel E. Jeffries; Craig W. Lindsley
- Source:
- Journal of organic chemistry 2019 v.84 no.9 pp. 5974-5979
- ISSN:
- 1520-6904
- Subject:
- chemical structure; chromatography; derivatization; lignans; organic chemistry; stereoselective synthesis
- Abstract:
- ... Lignans are a structurally diverse class of natural products with extensive pharmacological effects. Here we report the syntheses of both natural and unnatural dibenzylbutane lignans from a common intermediate, which is prepared in five steps from known materials. Derivatization of this intermediate affords lignans featuring contiguous stereocenters in a high diastereomeric purity after chromatogr ...
- DOI:
- 10.1021/acs.joc.9b00633
- https://doi.org/10.1021/acs.joc.9b00633
- Author:
- Xiang Dong Su; Wei Li; Jin Yeul Ma; Young Ho Kim
- Source:
- Natural product research 2018 v.32 no.19 pp. 2347-2351
- ISSN:
- 1478-6427
- Subject:
- Epimedium koreanum; aerial parts; chemical composition; chemical structure; chemotaxonomy; flavonoids; lignans; mass spectrometry; nuclear magnetic resonance spectroscopy; phenols
- Abstract:
- ... In this study, 21 compounds were isolated from the aerial parts of Epimedium koreanum Nakai, including 6 phenols (1–5 and 10), 4 lignans (6–9) and 11 flavonoids (11–21). The chemical structures of those isolates were established after extensive one-and two-dimensional nuclear magnetic resonance and mass spectroscopy analyses. This is the first report of compounds 2, 3, 4 and 9 in E. koreanum and o ...
- DOI:
- 10.1080/14786419.2017.1405412
- https://doi.org/10.1080/14786419.2017.1405412
- Author:
- Tianshan Wang; Xiaopeng Wu; Yanping Liu; Youping Luo; Xiang Li; Yujie Zhou; AiPing Yang; Zhengmeng Yan; Ling Ye; Siwei Chen; Jinshuai Fu; Xianzhi Jiao
- Source:
- Revista Brasileira de Farmacognosia 2018 v.28 no.2 pp. 235-238
- ISSN:
- 0102-695X
- Subject:
- Polyalthia; alkaloids; antineoplastic activity; branches; chemical composition; chemical structure; cytotoxicity; ethanol; gossypol; human cell lines; humans; inhibitory concentration 50; lignans; neoplasm cells; spectroscopy
- Abstract:
- ... Twelve known compounds, including eight alkaloids, three lignans and one gossypol derivative, were isolated from the branches of Polyalthia rumphii (Blume ex Hensch.) Merr., Annonaceae. The chemical structures were determined by spectroscopic methods and comparison with literature data. All the isolates were evaluated the cytotoxicity against three human cancer cell lines: Hela, MCF-7 and A549, th ...
- DOI:
- 10.1016/j.bjp.2018.03.004
- https://doi.org/10.1016/j.bjp.2018.03.004
- Author:
- Xiaojuan Wang; Jiabao Liu; Pankaj Pandey; Frank R. Fronczek; Robert J. Doerksen; Jiabao Chen; Xinzhu Qi; Peicheng Zhang; Daneel Ferreira; Frederick A. Valeriote; Hua Sun; Shuai Li; Mark T. Hamann
- Source:
- Organic letters 2018 v.20 no.18 pp. 5559-5563
- ISSN:
- 1523-7052
- Subject:
- Kadsura; X-ray diffraction; acetaminophen; carbon; chemical reactions; chemical structure; chemoprevention; circular dichroism spectroscopy; crystallography; cytotoxicity; hepatoprotective effect; lignans; nuclear magnetic resonance spectroscopy; roots
- Abstract:
- ... Kadsuraols A–C (1–3), which are tetrahydrocyclobutaphenanthrofuranone-type lignans with a new carbon skeleton comprising a four-membered ring across C-1′–C-8, have been isolated from the roots of Kadsura longipedunculata. Their structures and absolute configurations were unambiguously determined using nuclear magnetic resonance, X-ray diffraction crystallography, DP4+ calculations, and computed an ...
- DOI:
- 10.1021/acs.orglett.8b02207
- https://doi.org/10.1021/acs.orglett.8b02207
- Author:
- Shu-jun Shan; Jun Luo; De-ran Xu; Xing-liang Niu; Ding-qiao Xu; Pan-pan Zhang; Ling-yi Kong
- Source:
- Industrial crops and products 2018 v.112 pp. 830-838
- ISSN:
- 0926-6690
- Subject:
- Ginkgo biloba; antioxidant activity; antioxidants; bioactive compounds; butanol; chemical structure; flavonoids; functional foods; glycosides; inhibitory concentration 50; leaves; lignans; medicinal plants; medicine; nuclear magnetic resonance spectroscopy; phenylpropanoids; research and development; seeds; tandem mass spectrometry
- Abstract:
- ... Ginkgo biloba L. is a widely used medicinal plant that has a high concentration of its bioactive components, flavonoids and ginkgolides, in its leaves. Gingko seeds are also consumed as a functional food and medicine throughout the world to slow the ageing process. However, there have been few phytochemical studies of the phenylpropanoids from Ginkgo seeds. To elucidate the active components, we s ...
- DOI:
- 10.1016/j.indcrop.2017.12.013
- https://doi.org/10.1016/j.indcrop.2017.12.013
- Author:
- Hyoung-Geun Kim; Hyun-Ji Oh; Jung-Hwan Ko; Sun-Woo Joo; Yeong-Geun Lee; Yun-Su Baek; Dae Young Lee; Nam-In Baek
- Source:
- Chemistry of natural compounds 2019 v.55 no.4 pp. 610-613
- ISSN:
- 0009-3130
- Subject:
- Chrysanthemum morifolium; chemical structure; cultivars; glucosides; lignans; nuclear magnetic resonance spectroscopy; silica gel; spectral analysis; stems
- Abstract:
- ... A new neolignan glucoside has been isolated from Chrysanthemum morifolium ‘Baekma’ cultivar through repeated silica gel and octadecyl silica gel (ODS) column chromatographies. On the basis of spectroscopic data including NMR, MS, and IR, the chemical structure of the new neolignan glucoside was determined to be (7S,8S)-7-O-[1′-(4′,5′-dihydroxy-3′-methoxyphenyl)propanol]guaiacylglycerol 4-O-β-D-glu ...
- DOI:
- 10.1007/s10600-019-02760-1
- https://doi.org/10.1007/s10600-019-02760-1
- Author:
- Bing-You Yang; Zhang-Lin Chen; Yan Liu; Jiang-Tao Guo; Hai-Xue Kuang
- Source:
- Natural product research 2019 v.33 no.3 pp. 340-346
- ISSN:
- 1478-6427
- Subject:
- Calamus; Schisandra chinensis; chemical structure; cisplatin; cytotoxicity; human cell lines; inhibitory concentration 50; lignans; mass spectrometry; neoplasm cells; nuclear magnetic resonance spectroscopy; stems
- Abstract:
- ... A new lignan named schilignan F (1), together with twelve known ones (2–13), were isolated from the rattan stems of Schisandra chinensis. Their chemical structures were elucidated by spectroscopic methods including one and two-dimensional NMR spectra referring to the literatures as well as high-resolution mass spectrometric analysis. All compounds were evaluated for their cytotoxicities against hu ...
- DOI:
- 10.1080/14786419.2018.1452000
- https://doi.org/10.1080/14786419.2018.1452000
- Author:
- Yan Zhao; Wei Zhou; Shengbao Diao; Zhe Jiang; Mei Jin; Gao Li
- Source:
- Biochemical systematics and ecology 2019 v.87 pp. 103957
- ISSN:
- 0305-1978
- Subject:
- Juglans mandshurica; anthraquinones; chemical structure; chemotaxonomy; flavonoids; glycosides; lignans; naphthoquinones; nuclear magnetic resonance spectroscopy; phenols; roots; secoiridoids; secondary metabolites; triterpenoids
- Abstract:
- ... Phytochemical research of the roots of Juglans mandshurica Maxim. (Juglandaceae) verified 37 secondary metabolites, including thirteen diarylheptanoids (1–13), five naphthoquinones (14–18), five tetralones (19–23), three lignans (24–26), three phenols (27–29), two anthraquinones (30–31), two triterpenoids (32–33), two secoiridoids (34–35), one naphthalenyl glycoside (36), and one flavonoid (37). T ...
- DOI:
- 10.1016/j.bse.2019.103957
- https://doi.org/10.1016/j.bse.2019.103957
- Author:
- Ehu Camille Aka; Eric Wimmer; Elvina Barré; Natarajan Vasudevan; Daniel Cortés-Borda; Tchirioua Ekou; Lynda Ekou; Mireia Rodriguez-Zubiri; François-Xavier Felpin
- Source:
- Journal of organic chemistry 2019 v.84 no.21 pp. 14101-14112
- ISSN:
- 1520-6904
- Subject:
- algorithms; automation; catalysts; catalytic activity; chemical structure; closed loop systems; cobalt; dimerization; instrumentation; lignans; monitoring; oxidants; phenols; process control; screening; temperature
- Abstract:
- ... Naturally occurring benzoxanthenones, which belong to the vast family of lignans, are promising biologically relevant targets. They are biosynthetically produced by the oxidative dimerization of 2-propenyl phenols. In this manuscript, we disclose a powerful automated flow-based strategy for identifying and optimizing a cobalt-catalyzed oxidizing system for the bioinspired dimerization of 2-propeny ...
- DOI:
- 10.1021/acs.joc.9b02263
- https://doi.org/10.1021/acs.joc.9b02263
- Author:
- Yeong-Geun Lee; Isabel Rodriguez; Youn Hee Nam; Jung Eun Gwag; Sang Ho Woo; Hyoung-Geun Kim; Jung-Hwan Ko; Bin Na Hong; Tong Ho Kang; Nam-In Baek
- Source:
- Applied biological chemistry 2019 v.62 no.1 pp. 7
- ISSN:
- 2468-0842
- Subject:
- Danio rerio; Forsythia viridissima var. koreana; Microbacterium esteraromaticum; alloxan; butanol; chemical structure; flowers; glycosides; hypoglycemic agents; islets of Langerhans; lactones; lignans; methanol
- Abstract:
- ... Repeated column separation yielded four enterolactone type lignans from Forsythia koreana flowers (FKF), whose chemical structures were identified using several spectral technics. FKF MeOH extract (FKFM) and four lignans significantly recovered aloxan induced pancreatic islet in zebrafish. Especially, aglycones, 1 and 3, exhibited relatively higher activity than the lignan glycosides, 2 and 4. The ...
- DOI:
- 10.1186/s13765-019-0411-y
- https://doi.org/10.1186/s13765-019-0411-y
- Author:
- Diana I. Saavedra; Benjamin D. Rencher; Doo-Hyun Kwon; Stacey J. Smith; Daniel H. Ess; Merritt B. Andrus
- Source:
- Journal of organic chemistry 2018 v.83 no.4 pp. 2018-2026
- ISSN:
- 1520-6904
- Subject:
- antineoplastic activity; antineoplastic agents; chemical structure; cycloaddition reactions; density functional theory; hydrogen; lignans; organic chemistry; secondary metabolites
- Abstract:
- ... Deoxypodophyllotoxin is a secondary metabolite lignan possessing potent anticancer activity with potential as a precursor for known anticancer drugs, but its use is limited by scarcity from natural sources. We here report the total synthesis of racemic deoxypodophyllotoxin in seven steps using an intramolecular styryl Diels–Alder reaction strategy uniquely suited to assemble the deoxypodophyllotox ...
- DOI:
- 10.1021/acs.joc.7b02957
- https://doi.org/10.1021/acs.joc.7b02957
- Author:
- Peter Hartmann; Mattia Lazzarotto; Lorenz Steiner; Emmanuel Cigan; Silvan Poschenrieder; Peter Sagmeister; Michael Fuchs
- Source:
- Journal of organic chemistry 2019 v.84 no.9 pp. 5831-5837
- ISSN:
- 1520-6904
- Subject:
- aldehydes; allylation; chemical structure; hydrogen; lignans; organic chemistry; organobromine compounds; phosphates; stereoselective synthesis
- Abstract:
- ... The asymmetric allylation under the assistance of catalytic amounts of 3,3′-bis(2,4,6-triisopropylphenyl)-1,1′-binaphthyl-2,2′-diyl hydrogen phosphate (TRIP) allows the concise construction of the lignan scaffold from simple aldehydes and allylic bromides with full control of the two formed stereocenters. This young methodology has been employed to synthesize four naturally and pharmaceutically ac ...
- DOI:
- 10.1021/acs.joc.9b00065
- https://doi.org/10.1021/acs.joc.9b00065
- Author:
- Ruth Anyango Omole; Mainen Julius Moshi; Matthias Heydenreich; Hamisi Masanja Malebo; Jeremiah Waweru Gathirwa; Sharon Alice Ochieng’; Leonida Kerubo Omosa; Jacob Ogweno Midiwo
- Source:
- Phytochemistry letters 2019 v.30 pp. 194-200
- ISSN:
- 1874-3900
- Subject:
- Hypoestes; Plasmodium falciparum; antiplasmodial properties; chemical structure; diterpenoids; inhibitory concentration 50; lignans; parasites; screening; ultraviolet-visible spectroscopy
- Abstract:
- ... Bioassay-guided screening of Hypoestes verticillaris whole plant CH2Cl2:MeOH (1:1) extract for anti-plasmodial activity yielded four new compounds: two lignans 2, 6-dimethoxysavinin (1), 2,6-dimethoxy-(7E)-7,8-dehydroheliobuphthalmin (2); and two fusicoccane diterpenoids: 11(12)-epoxyhypoestenone (3) and 3(11)-epoxyhypoestenone (4). The chemical structures were determined using various spectroscop ...
- DOI:
- 10.1016/j.phytol.2019.02.019
- https://doi.org/10.1016/j.phytol.2019.02.019
- Author:
- Bo Liu; Shou-Zhen Du; Fang Kuang; Ying Liu; Xing-Jun Tian; Ye-Gao Chen; Rui Zhan
- Source:
- Natural product research 2019 v.33 no.1 pp. 95-100
- ISSN:
- 1478-6427
- Subject:
- branches; chemical structure; cytotoxicity; humans; leaves; lignans; neoplasms; spectral analysis
- Abstract:
- ... Two new dibenzylbutyrolactol lignans and three known dibenzylbutyrolactone lignans were isolated from the twigs and leaves of Horsfieldia kingii. Their structures were elucidated by spectroscopic analysis. Cytotoxicity evaluation of these compounds against five human tumour lines showed no inhibitory effects. ...
- DOI:
- 10.1080/14786419.2018.1437429
- https://doi.org/10.1080/14786419.2018.1437429
- Author:
- Yang Zhang; Bowen Deng; Yida Cui; Xue Chen; Jiayi Bi; Guogang Zhang
- Source:
- Natural medicines 2018 v.72 no.4 pp. 946-953
- ISSN:
- 1340-3443
- Subject:
- Ilex pubescens; chemical structure; glucosides; lignans; nuclear magnetic resonance spectroscopy; roots
- Abstract:
- ... Two new secoiridoid glucosides, ilexpublignoside (1), pubzenoside (2), and a new lignan, ilexlignan B (3), along with seven known compounds (4–10) were isolated from the roots of Ilex pubescens for the first time. Their chemical structures were elucidated on the basis of extensive spectroscopic methods, including IR, UV, HR-ESI–MS, CD, NMR experiments, as well as comparison with the reported data. ...
- DOI:
- 10.1007/s11418-018-1227-5
- https://doi.org/10.1007/s11418-018-1227-5
34. The total synthesis of sevanol, a novel lignan isolated from the thyme plant (Thymus armeniacus)
- Author:
- O.A. Belozerova; V.I. Deigin; A.Yu. Khrushchev; M.A. Dubinnyi; V.S. Kublitski
- Source:
- Tetrahedron 2018 v.74 pp. 1449-1453
- ISSN:
- 0040-4020
- Subject:
- bioactive properties; chemical structure; dimerization; ferric chloride; lignans; thyme
- Abstract:
- ... Recently, a novel lignan sevanol was isolated from the thyme plant Thymus armeniacus. During structure-functional elucidation it showed significant biological activity on ASIC3 acid sensing channels. Herein we describe the first synthesis of sevanol with a 3% overall yield. The construction of a dihydronaphthalene ring by oxidative dimerization of a protected dihydroxycinnamic acid ester in the pr ...
- DOI:
- 10.1016/j.tet.2018.02.005
- https://doi.org/10.1016/j.tet.2018.02.005
- Author:
- Wei Zhou; Jinjun Shan; Minxin Meng
- Source:
- Journal of chromatography 2018 v.1563 pp. 99-123
- ISSN:
- 0021-9673
- Subject:
- bioactive compounds; blood; caffeic acid; chemical structure; chlorogenic acid; chromatography; fever; herbal medicines; human serum albumin; inflammation; kaempferol; lignans; liquids; mass spectrometry; metabolites; molecular models; monoterpenoids; oleanolic acid; prototypes; quercetin; rats; reference standards; saponins; screening
- Abstract:
- ... Fructus Gardeniae-Fructus Forsythiae herb pair is an herbal formula used extensively to treat inflammation and fever, but few systematic identification studies of the bioactive components have been reported. Herein, the unknown analogues in the first-step screening were rapidly identified from representative compounds in different structure types (geniposide as iridoid type, crocetin as crocetin t ...
- DOI:
- 10.1016/j.chroma.2018.05.067
- https://doi.org/10.1016/j.chroma.2018.05.067
- Author:
- Gustav Komlaga; Grégory Genta-Jouve; Sandrine Cojean; Rita A. Dickson; Merlin L.K. Mensah; Philippe M. Loiseau; Pierre Champy; Mehdi A. Beniddir
- Source:
- Tetrahedron letters 2017 pp. -
- ISSN:
- 0040-4039
- Subject:
- Phyllanthus fraternus; Plasmodium falciparum; Securinega; alkaloids; antimalarials; antiparasitic properties; chemical reactions; chemical structure; inhibitory concentration 50; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
- Abstract:
- ... The chemical investigation of the antimalarial plant Phyllanthus fraternus G. L. Webster (Phyllanthaceae) resulted in the discovery of the Securinega alkaloid (+)-allonorsecurinine (1), previously reported as a synthetic compound, together with the known ent-norsecurinine (2), nirurine (3), bubbialine (4), epibubbialine (5) and the lignan phyllanthin (6). The structure and absolute configuration o ...
- DOI:
- 10.1016/j.tetlet.2017.08.045
- https://doi.org/10.1016/j.tetlet.2017.08.045
- Author:
- Manat Pohmakotr; Chutima Kuhakarn; Vichai Reutrakul; Darunee Soorukram
- Source:
- Tetrahedron letters 2017 pp. -
- ISSN:
- 0040-4039
- Subject:
- bioactive properties; chemical reactions; chemical structure; lignans; stereochemistry; stereoselectivity
- Abstract:
- ... Furofurans are one of the largest sub-types of classical lignans which have been found to possess a broad range of important biological activities. Tremendous efforts have been directed to develop synthetic methodologies for the synthesis of furofurans, especially in a stereoselective manner, due to their interesting bioactivities associated with the structural and stereochemical complexity. This ...
- DOI:
- 10.1016/j.tetlet.2017.11.011
- https://doi.org/10.1016/j.tetlet.2017.11.011
- Author:
- Darunee Soorukram; Manat Pohmakotr; Chutima Kuhakarn; Vichai Reutrakul
- Source:
- Journal of organic chemistry 2018 v.83 no.7 pp. 4173-4179
- ISSN:
- 1520-6904
- Subject:
- biochemical pathways; chemical reactions; chemical structure; lignans; organic chemistry; stereoselectivity
- Abstract:
- ... A bioinspired asymmetric total synthesis of a structurally unique subtype of lignan, namely, (−)-gymnothelignan V, was achieved. The key synthetic sequences involved reduction of the eupomatilone skeleton leading to (−)-gymnothelignan J followed by the formation of the corresponding oxocarbenium ion and stereoselective intramolecular Friedel–Crafts reaction. Our synthetic approach provides the inf ...
- DOI:
- 10.1021/acs.joc.8b00164
- https://doi.org/10.1021/acs.joc.8b00164
- Author:
- Zhao Jin-Xin; Fan Yao-Yue; Xu Jin-Biao; Gan Li-She; Xu Cheng-Hui; Ding Jian; Yue Jian-Min
- Source:
- Journal of natural products 2017 v.80 no.2 pp. 356-362
- ISSN:
- 1520-6025
- Subject:
- Cephalotaxus; X-ray diffraction; anticarcinogenic activity; biosynthesis; branches; chemical structure; cytotoxicity; diterpenoids; inhibitory concentration 50; leaves; lignans
- Abstract:
- ... Five new diterpenoids including two Cephalotaxus troponoids (1 and 2), two 17-nor-cephalotane-type diterpenoids (3 and 4), and an abietane-type diterpenoid (5), two new lignans (6 and 7), and a new trisnorneoligan (8) along with eight known compounds were identified from the twigs and leaves of Cephalotaxus fortunei. The structure of 11-hydroxyhainanolidol was revised as 10-hydroxyhainanolidol (9) ...
- DOI:
- 10.1021/acs.jnatprod.6b00802
- https://doi.org/10.1021/acs.jnatprod.6b00802
- Author:
- Le Zhou; Li-Li Lou; Wei Wang; Bin Lin; Jun-Ning Chen; Xiao-Bo Wang; Xiao-Xiao Huang; Shao-Jiang Song
- Source:
- Journal of functional foods 2017 v.37 pp. 322-329
- ISSN:
- 1756-4646
- Subject:
- Alzheimer disease; Rubus idaeus; chemical composition; chemical structure; functional foods; lignans; neuroprotective effect; spectral analysis; stereochemistry
- Abstract:
- ... Red raspberry (Rubus idaeus L.) is an edible fruit-producing species belonging to the Rosaceae family. In our search for potential agents for treating Alzheimer’s disease in this functional food, we decided to investigate the chemical constituents of red raspberry. Four pairs of enantiomeric 8-O-4′-type neolignans (1a/1b–4a/4b), including three new compounds (1a/1b and 2a), were identified from th ...
- DOI:
- 10.1016/j.jff.2017.08.007
- https://doi.org/10.1016/j.jff.2017.08.007
- Author:
- Jiabao Liu; Pankaj Pandey; Xiaojuan Wang; Xinzhu Qi; Jiabao Chen; Hua Sun; Peicheng Zhang; Yuanqing Ding; Daneel Ferreira; Robert J. Doerksen; Mark T. Hamann; Shuai Li
- Source:
- Journal of natural products 2018 v.81 no.4 pp. 846-857
- ISSN:
- 1520-6025
- Subject:
- Kadsura; cell viability; chemical structure; circular dichroism spectroscopy; hepatoprotective effect; human cell lines; lignans; mass spectrometry; nuclear magnetic resonance spectroscopy; roots; survival rate; toxicity
- Abstract:
- ... Five new dibenzocyclooctadiene lignans, longipedlignans A–E (1–5), five new tetrahydrobenzocyclooctabenzofuranones (6–10), and 18 known analogues (11–28) were isolated from the roots of Kadsura longipedunculata. Compounds 6–10 are new spirobenzofuranoid–dibenzocyclooctadiene-type lignans. Their structures and absolute configurations were established using a combination of MS, NMR, and electronic c ...
- DOI:
- 10.1021/acs.jnatprod.7b00934
- https://doi.org/10.1021/acs.jnatprod.7b00934
- Author:
- Takahiro Matsumoto; Seikou Nakamura; Souichi Nakashima; Tomoe Ohta; Keiko Ogawa; Masashi Fukaya; Junko Tsukioka; Tomohiro Hasei; Tetsushi Watanabe; Hisashi Matsuda
- Source:
- Phytochemistry 2017 v.137 pp. 101-108
- ISSN:
- 0031-9422
- Subject:
- aerial parts; chemical structure; cytotoxicity; glucosides; lignans; nuclear magnetic resonance spectroscopy; protective effect; spectral analysis; Japan
- Abstract:
- ... Six neolignan glucosides, named isodonosides I–VI, and a megastigmane glucoside named isodonmegastigmane I, were isolated together with 15 known compounds from the methanolic extract of aerial parts of Isodon japonicus cultivated in Tokushima, Japan. The chemical structures of the compounds were elucidated based on their MS and NMR spectroscopic analysis. The absolute configurations of the neolign ...
- DOI:
- 10.1016/j.phytochem.2017.02.007
- https://doi.org/10.1016/j.phytochem.2017.02.007
- Author:
- Seoung Rak Lee; Eunjung Moon; Ki Hyun Kim
- Source:
- Phytochemistry letters 2017 v.20 pp. 98-101
- ISSN:
- 1874-3900
- Subject:
- Ipomoea nil; anti-inflammatory activity; chemical structure; cytotoxicity; ethanol; glycosides; inhibitory concentration 50; lignans; lipopolysaccharides; mice; monoterpenoids; nitric oxide; nuclear magnetic resonance spectroscopy; seeds; spectral analysis
- Abstract:
- ... Phytochemical investigation of an EtOH extract of Pharbitis nil seeds (Convolvulaceae) resulted in the isolation and identification of a new neolignan, 7R,8S-threo-dihydroxydehydrodiconiferyl alcohol (1), and a new monoterpene glycoside, (3Z,7S)-7-hydroxy-3,7-dimethyl-3,8-octadienyl-β-d-glucopyranoside (2), together with a known compound, ethyl α-l-arabinofuranoside (3). The chemical structures of ...
- DOI:
- 10.1016/j.phytol.2017.04.019
- https://doi.org/10.1016/j.phytol.2017.04.019
- Author:
- Liu Ye; Yu Heng-Yi; Wang Yan-Mei; Tian Tian; Wu Wen-Ming; Zhou Ming; Meng Xiang-Gao; Ruan Han-Li
- Source:
- Journal of natural products 2017 v.80 no.4 pp. 1117-1124
- ISSN:
- 1520-6025
- Subject:
- Schisandra; X-ray diffraction; chemical structure; fruits; hydrogen peroxide; irradiation; lignans; models; neuroprotective effect; spectral analysis
- Abstract:
- ... Nine new lignans (1–9) and ten known analogues (10–19) were isolated from the fruits of Schisandra bicolor var. tuberculata. The structures of compounds 1–9 were established on the basis of spectroscopic data analysis. The absolute configuration of compound 1 was determined by single-crystal X-ray diffraction analysis with Cu Kα irradiation techniques, and the absolute configurations of compounds ...
- DOI:
- 10.1021/acs.jnatprod.7b00035
- https://doi.org/10.1021/acs.jnatprod.7b00035
- Author:
- Jia Chen; Chun-Chao Zhao; Jian-Hua Shao; Ju-Di Fan; Xu-Hua Huang
- Source:
- Chemistry of natural compounds 2017 v.53 no.4 pp. 626-628
- ISSN:
- 0009-3130
- Subject:
- Galium verum; Helicoverpa armigera; Scorpiones; chemical structure; glucosides; insecticidal properties; lignans; mortality; poisoning; scorpion venoms; spectral analysis; stomach; toxicity
- Abstract:
- ... A new lignan glucoside, galiveroside A (1), and seven known compounds (2–8), were isolated from Galium verum L. The structure of 1 was elucidated on the basis of extensive spectroscopic analyses. Compound 1, at the concentration of 5 mg/mL, showed insecticide activity to 3 age cotton bollworm with a mortality of 16.3% through stomach poisoning. When combined with a recombinant scorpion toxin rLqh ...
- DOI:
- 10.1007/s10600-017-2075-3
- https://doi.org/10.1007/s10600-017-2075-3
- Author:
- Jian-Hua Shao; Xue-Wei Zhang; Zi-Ling Dong; Si-Hui Li; Ben-Jie Miao; Ke-Zhi Cheng
- Source:
- Chemistry of natural compounds 2017 v.53 no.6 pp. 1025-1027
- ISSN:
- 0009-3130
- Subject:
- Cyclea; chemical structure; glucosides; lignans; spectral analysis
- Abstract:
- ... A new lignan glucoside 1, along with two known lignans (2, 3), was isolated from Cyclea racemosa Oliv. Its structure was elucidated as (+)-7′-methoxylariciresinol 4-O-β-D-glucopyranoside on the basis of extensive spectroscopic analyses. ...
- DOI:
- 10.1007/s10600-017-2193-y
- https://doi.org/10.1007/s10600-017-2193-y
- Author:
- Lorenzo Cecchi; Marzia Innocenti; Fabrizio Melani; Marzia Migliorini; Lanfranco Conte; Nadia Mulinacci
- Source:
- Food chemistry 2017 v.219 pp. 148-157
- ISSN:
- 0308-8146
- Subject:
- bleaching; chemical structure; chromatography; deodorization; extra-virgin olive oil; lignans; oil refining; Italy; Spain; Tunisia
- Abstract:
- ... Herein we describe the influence of olive oil refining processes on the lignan profile. The detection of new isobaric lignans is suggested to reveal frauds in commercial extra-Virgin Olive Oils. We analyzed five commercial olive oils by HPLC-DAD-TOF/MS to evaluate their lignan content and detected, for the first time, some isobaric forms of natural (+)-pinoresinol and (+)-1-acetoxypinoresinol. The ...
- DOI:
- 10.1016/j.foodchem.2016.09.132
- https://doi.org/10.1016/j.foodchem.2016.09.132
- Author:
- Bing-You Yang; Yu-Meng Luo; Yan Liu; Xin Yin; Yuan-Yuan Zhou; Hai-Xue Kuang
- Source:
- Phytochemistry letters 2018 v.28 pp. 8-12
- ISSN:
- 1874-3900
- Subject:
- Datura metel; chemical structure; cytotoxicity; lignans; mass spectrometry; nuclear magnetic resonance spectroscopy; roots
- Abstract:
- ... Two new lignans (1-2) and a new natural product (3), as well as eighteen known compounds (4-21), were isolated from the roots of Datura metel L. Compounds 8, 11, 12, 14, 16, 17, 19 and 21 were isolated from Datura metel L for the first time. These compounds’ chemical structures were elucidated by spectroscopic methods, including 1D and 2D NMR spectra with references to the literature, as well as h ...
- DOI:
- 10.1016/j.phytol.2018.08.002
- https://doi.org/10.1016/j.phytol.2018.08.002
- Author:
- Yunzhi Li; Hui Cheng; Ren Yue; Mengmeng Duan; Mingdong Liu
- Source:
- Natural product research 2017 v.31 no.9 pp. 1047-1051
- ISSN:
- 1478-6427
- Subject:
- Aralia; chemical structure; ionization; lignans; nuclear magnetic resonance spectroscopy; saponins
- Abstract:
- ... A phytochemical investigation was carried out to the root of Aralia echinocauis , and a new neolignan glycoside, 3-{3,5-dimethoxy-4β- d -Glucopyranoside-2-[3-(3-β- d -Glucopyranoside-4-methoxy-phenyl)-allyl]-phenyl}-prop-2-en-1-ol (1), together with a known saponin, araliasaponin II (2) for the first time was obtained . The chemical structure of compound 1 was identified mainly by the analysis of ...
- DOI:
- 10.1080/14786419.2016.1269095
- https://doi.org/10.1080/14786419.2016.1269095
- Author:
- Sonda Ammar; Maria del Mar Contreras; Boutheina Gargouri; Antonio Segura‐Carretero; Mohamed Bouaziz
- Source:
- Phytochemical analysis 2017 v.28 no.3 pp. 217-229
- ISSN:
- 0958-0344
- Subject:
- Olea europaea; aldehydes; bioactive compounds; bioactive properties; byproducts; chemical structure; coumarins; cultivars; flavonoids; high performance liquid chromatography; leaves; lignans; mass spectrometry; metabolites; metabolomics; olives; phenolic acids; phytopharmaceuticals; roots; secoiridoids; stems; sugars; trees; wood
- Abstract:
- ... INTRODUCTION: Olea europaea L. organs such as leaves, stems and roots have been associated with numerous in vivo and in vitro biological activities and used for traditional medicinal purposes. However, tree wood is an untapped resource with little information about their chemical composition. OBJECTIVE: That is why, the objective of this study is to increase the knowledge about phytochemicals from ...
- DOI:
- 10.1002/pca.2664
- https://doi.org/10.1002/pca.2664