An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Sesamum indicum; seeds; furans; lignans; spectral analysis; chemical structure; biosynthesis; biochemical pathways; chemical reactions; chemical constituents of plants
Apiaceae; lignans; lactones; spectral analysis; chemical structure; antineoplastic agents; humans; ovarian diseases; chemical constituents of plants; Tanzania
... Four new abscisic acid related compounds (1-4), together with (+)-abscisic acid (5), (+)-β-D-glucopyranosyl abscisate (6), (6S,9R)-roseoside (7), and two lignan glucosides ((+)-pinoresinol mono-β-D-glucopyranoside (8) and 3-(β-D-glucopyranosyloxymethyl)-2- (4-hydroxy-3-methoxyphenyl)-5-(3-hydroxypropyl)-7-methoxy-(2R,3S)-dihydrobenzofuran (9)) were isolated from the antioxidative ethanol extract o ...
Macaranga tanarius; lignans; glucosides; chemical constituents of plants; chemical structure; spectral analysis; stereochemistry; antioxidant activity; Japan
Abstract:
... A lignan glucoside, (+)-pinoresinol 4-O-[6"-O-galloyl]-β-d-glucopyranoside (1), and two megastigmane glucosides, named macarangiosides E and F (2, 3), together with 15 known compounds (4-18) were isolated from leaves of Macaranga tanarius (L.) Müll.-Arg. (Euphorbiaceae). Their structures were elucidated by spectroscopic and chemical analyses. In addition, the absolute stereochemistry of macarangi ...
Agastache; medicinal plants; lignans; spectral analysis; chemical structure; apoptosis; leukemia; cell lines; chemical constituents of plants; South Korea
... The reversed-phase preparative HPLC analysis of the methanol (MeOH) extract of the seeds of Centaurea americana afforded a dibenzylbutyrolactone lignan, 3"-O-caffeoyl arctiin (named americanin), together with five known lignans, arctiin, arctigenin, matairesinol, matairesinoside and lappaol A, and two known phytoecdysteroids, 20-hydroxyecdysone and makisterone A. While the structures of the known ...
Phyllanthus urinaria; plant extracts; phytochemicals; lignans; chemical structure; chemical analysis; reversed-phase high performance liquid chromatography; nuclear magnetic resonance spectroscopy
Abstract:
... HPLC-SPE-NMR has been applied to the analysis of a number of structurally similar lignans present in Phyllanthus urinaria. A reversed-phase HPLC system, using a C8 column eluted with tetrahydrofuran-water-methanol and detected at 225 nm was developed that gave good resolution for seven lignans from Phyllanthus urinaria. Coupling of this system with SPE-NMR provided clean 1H-NMR spectra for nine li ...
Human immunodeficiency virus 1; Justicia procumbens; Oriental traditional medicine; acetates; antiretroviral properties; chemical structure; cytotoxicity; inhibitory concentration 50; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... Twenty-one lignans including three new ones (1, 2 and 13) were isolated from Justicia procumbens. The chemical structures of the new lignans were determined by spectroscopic means including 1D and 2D NMR analysis. These compounds were evaluated for their cytotoxic and anti-HIV activities. The new secoisolariciresinol dimethyl ether acetate (13) exhibited anti-HIV-1 activity with an IC50 value of 5 ...
terpenoids; complement; human health; lignans; spectral analysis; hemolysis; medicinal properties; stereochemistry; chemical structure; Styrax japonicus; South Korea
anti-inflammatory activity; nitric oxide synthase; Tripterygium wilfordii; interleukin-1; phytochemicals; immunosuppression; macrophages; medicinal plants; mice; lignans; spectral analysis; prostaglandin synthase; gene expression regulation; stereochemistry; chemical structure; Oriental traditional medicine; China
Abstract:
... The extract of Tripterygium wilfordii Hook F. (TwHF), which showed anti-inflammatory and immunosuppressive activities in human clinical trials for rheumatoid arthritis, was subjected to the activity-guided fractionation and spectroscopic characterization of bioactives. A tetrahydrofuran lignan, tripterygiol (1), and eight known compounds, all capable of suppressing pro-inflammatory gene expression ...
... A new flavonolignan, anthelminthicol A (1), together with four known compounds, was isolated from the EtOAc extracts of the seeds of Hydnocarpus anthelminthica. Their structures were elucidated using extensive spectroscopic techniques. Bioassay showed that compounds 3–5 could inhibit nitric oxide production in LPS-stimulated RAW 264.7 macrophage cell lines, with IC₅₀ values of 7.81, 9.38, and 10.5 ...