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1. "Aurora tropical": integrating the use of biostimulants in sustainable horticulture, the case for fruit extracts and chitosan in pepper seedling production

Author:
Ramírez-Guerrero, H.O.; Santana-Gudiño, Y.A.; Meza-Figueroa, C.A.
Source:
Acta horticulturae 2012 no.1009 pp. 101-104
ISSN:
0567-7572
Subject:
biofortification; chitosan; citric acid; climate change; commercial horticulture; educational research; fruit extracts; growers; juices; leaves; mosses and liverworts; peat; pepper; seedling growth; seedling production; seedlings; solid wastes; surveys; sustainable agriculture; sweet peppers; tap water; toxicity; trays; vegetable growing; watermelons
Abstract:
... Despite recent reports indicating that tropical countries will suffer most from the negative impacts of climate change, including numerous educational and research campaigns, current surveys examining trends in good horticultural practices show that the majority of tropical vegetable growers are still using conventional production methods. In this experiment bell pepper seedlings were grown in tra ...

2. L( +)-Lactic Acid Production by Immobilized Lactobacillus casei Using Low Cost Agro-Industrial Waste as Carbon and Nitrogen Sources

Author:
Avinash Thakur; Parmjit Singh Panesar; Manohar Singh Saini
Source:
Waste and biomass valorization 2019 v.10 no.5 pp. 1119-1129
ISSN:
1877-2641
Subject:
Lactobacillus casei; agricultural wastes; batch fermentation; biomass; carbon; chitosan; corn steep liquor; immobilized cells; lactic acid; molasses; nitrogen; pH; porosity; sodium alginate; temperature
Abstract:
... Batch fermentation of molasses for L(+) lactic acid production using corn steep liquor (CSL) as nitrogen source by immobilized Lactobacillus (Lb.) casei MTCC 1423 has been studied. Among different tested immobilizing matrices, sodium alginate has been observed to be the best matrix for L(+)-lactic acid production. Significant reduction in cell release with double layer coated (chitosan and alginat ...
DOI:
10.1007/s12649-017-0129-1

3. 1, 3β-Glucan anchored, paclitaxel loaded chitosan nanocarrier endows enhanced hemocompatibility with efficient anti-glioblastoma stem cells therapy

Author:
Pankaj K. Singh; Anup K. Srivastava; Atul Dev; Babita Kaundal; Subhasree Roy Choudhury; Surajit Karmakar
Source:
Carbohydrate polymers 2018 v.180 pp. 365-375
ISSN:
0144-8617
Subject:
inhibitory concentration 50; intravenous injection; neoplasms; bioavailability; cytotoxicity; chitosan; drugs; stem cells; nanocarriers; hemolysis; paclitaxel; nanoparticles
Abstract:
... Recurrence of glioblastoma is one of the major concerns due to its heterogeneous nature and association of Glioma Initiating stem-like Cells (GICs). Nanoparticles mediated delivery of chemotherapeutic agent targeting both cancer and glioma stem cells could provide a solution to recurrent malignancies of the glioblastoma tumor. The approach described here provides enhanced chemotherapeutic potency ...
DOI:
10.1016/j.carbpol.2017.10.030

4. 1,3,5-Triazine-2,4,6-tribenzaldehyde derivative as a new crosslinking agent for synthesis of pH-thermo dual responsive chitosan hydrogels and their nanocomposites: Swelling properties and drug release behavior

Author:
Ali Reza Karimi; Mahsa Tarighatjoo; Golara Nikravesh
Source:
International journal of biological macromolecules 2017 pp. -
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; aldehydes; carbon nanotubes; chitosan; cross-linking reagents; crosslinking; drugs; hydrogels; metronidazole; models; nanocomposites; nuclear magnetic resonance spectroscopy; pH; scanning electron microscopy; temperature
Abstract:
... In this work, 1,3,5-triazine-2,4,6-tribenzaldehyde was synthesized and chosen as the cross-linking agent for preparation of novel thermo- and pH-responsive hydrogels based on chitosan. The cross-linking proceeds through formation of imine bond by reaction of amino groups of chitosan with aldehyde groups of the cross-linker. The various amounts (6, 10, 14% w/w) of the cross-linker were used with re ...
DOI:
10.1016/j.ijbiomac.2017.07.128

5. 1H NMR and 1H–13C HSQC surface characterization of chitosan–chitin sheath-core nanowhiskers

Author:
Antonio G.B. Pereira; Edvani C. Muniz; You-Lo Hsieh
Source:
Carbohydrate polymers 2015 v.123 pp. 46-52
ISSN:
0144-8617
Subject:
acetone; acetylation; acid hydrolysis; chitin; chitosan; colloids; crystal structure; deuterium oxide; glucosamine; hydrochloric acid; hydrogen; nanocrystals; nuclear magnetic resonance spectroscopy; sodium hydroxide
Abstract:
... Surface deacetylation of chitin nanowhiskers (CtNWs) to chitosan–sheath/chitin-core nanowhiskers (CsNWs) was successfully monitored by liquid-state high-resolution NMR of colloidal suspensions of these never-dried nanowhiskers. CtNWs were derived from acid hydrolysis (3N HCl, 30mL/g, 90min, 104°C) of chitin at 65% yield and 86% CrI. Deacetylation (50% NaOH, 48h, 50°C) of CtNWs generated CsNWs with ...
DOI:
10.1016/j.carbpol.2015.01.017

6. 1H NMR characterization of chitin tetrasaccharide in binary H2O:DMSO solution: Evidence for anomeric end-effect propagation

Author:
Kecheng Li; Andrew R. Green; Meredith M. Dinges; Cynthia K. Larive
Source:
International journal of biological macromolecules 2019 v.129 pp. 744-749
ISSN:
0141-8130
Subject:
bioactive compounds; chitin; chitosan; elicitors; immune response; microstructure; nodulation; nuclear magnetic resonance spectroscopy; oligosaccharides; solvents
Abstract:
... Chitin oligosaccharides, composed of homogeneous β(1 → 4)-linked N-acetyl-D-glucosamine (GlcNAc) sequences, is a well-known elicitor of plant immune defense, and also occur as structural elements of chitosan and nodulation (Nod) factor. Detailed microstructure characterization is required for understanding the function mode of these bioactive molecules. Herein, experimental conditions for detectio ...
DOI:
10.1016/j.ijbiomac.2019.02.062

7. 1H NMR studies of molecular interaction of D-glucosamine and N-acetyl-D-glucosamine with capsaicin in aqueous and non-aqueous media

Author:
Inocencio Higuera-Ciapara; Claudia Virués; Marcela Jiménez-Chávez; Evelin Martínez-Benavidez; Javier Hernández; Zaira Domínguez; Roberto López-Rendón; Enrique F. Velázquez; Motomichi Inoue
Source:
Carbohydrate research 2017 v.452 pp. 6-16
ISSN:
0008-6215
Subject:
N-acetylglucosamine; bioactive compounds; capsaicin; cations; chitosan; deuterium oxide; dimethyl sulfoxide; glucosamine; hot peppers; hydrogen bonding; isomers; models; monosaccharides; nanocarriers; nuclear magnetic resonance spectroscopy; stoichiometry; thermodynamics; titration; van der Waals forces
Abstract:
... Complex formation of D-glucosamine (Gl) and N-acetyl-D-glucosamine (AGl) with capsaicin (Cp) were studied by 1H NMR titrations in H2O-d2 and DMSO-d6; capsaicin is the major bioactive component of chili peppers. Every titration curve has been interpreted by formulating a suitable model for the reaction equilibrium, to elucidate intermolecular interactions. In DMSO, glucosamine cations associate wit ...
DOI:
10.1016/j.carres.2017.09.014

8. 2,5-Dimethoxy 2,5-dihydrofuran crosslinked chitosan fibers enhance bone regeneration in rabbit femur defects

Author:
Paulomi Ghosh; Arun Prabhu Rameshbabu; Nantu Dogra; Santanu Dhara
Source:
RSC advances 2014 v.4 no.37 pp. 19516-19524
ISSN:
2046-2069
Subject:
adhesion; adsorption; alkaline phosphatase; animal models; bone formation; bone marrow; calcium; cell proliferation; chemical bonding; chitosan; crosslinking; extracellular matrix; femur; glucosamine; histology; humans; hydrophobicity; imines; in vivo studies; mesenchymal stromal cells; neutralization; osteocalcin; pH; polymers; rabbits; secretion; sodium hydroxide; tensile strength; tissue engineering
Abstract:
... Chitosan fibers were fabricated via pH induced neutralization and precipitation in a 5 w/v% NaOH bath. Intermolecular covalent crosslinking of these fibers were performed through imine linkages between the glucosamine units of polymers and the dialdehyde groups of 2,5-dimethoxy-2,5-dihydrofuran at 60 °C, pH 2.2. The covalently crosslinked fibers demonstrated improved tensile strength, stiffness, h ...
DOI:
10.1039/c4ra01971g

9. The 21st century revival of chitosan in service to bio-organic chemistry

Author:
Zvezdelina Yaneva; Donika Ivanova; Nevena Nikolova; Milena Tzanova
Source:
Biotechnology, biotechnological equipment 2020 v.34 no.1 pp. 221-237
ISSN:
1314-3530
Subject:
biopolymers; biotechnology; chitosan; encapsulation; equipment; food industry; medicine; nanocarriers; research and development
Abstract:
... The design and synthesis of biopolymer nano- and micro-formulations are a new trend with growing priority in scientific research and development in the fields of biomedicine, bioorganic/medicinal chemistry, pharmaceutics, agrochemistry and food industry. This incorporates a vast variety of improved and newly-developed analytical and physico-chemical techniques for green and efficient synthesis. Th ...
DOI:
10.1080/13102818.2020.1731333

10. 3,6-O-[N-(2-Aminoethyl)-acetamide-yl]-chitosan exerts antibacterial activity by a membrane damage mechanism

Author:
Feilong Yan; Qifeng Dang; Chengsheng Liu; Jingquan Yan; Teng Wang; Bing Fan; Dongsu Cha; Xiaoli Li; Shengnan Liang; Zhenzhen Zhang
Source:
Carbohydrate polymers 2016 v.149 pp. 102-111
ISSN:
0144-8617
Subject:
Escherichia coli; Staphylococcus aureus; antibacterial properties; bacteria; cell membranes; cell viability; chitosan; electrical conductivity; food preservatives; hydrophobicity; membrane permeability; minimum inhibitory concentration; nucleic acids; polyacrylamide gel electrophoresis; proteins; scanning electron microscopy; water solubility
Abstract:
... A novel chitosan derivative, 3,6-O-[N-(2-aminoethyl)-acetamide-yl]-chitosan (AACS), was successfully prepared to improve water solubility and antibacterial activity of chitosan. AACS had good antibacterial activity, with minimum inhibitory concentrations of 0.25mg/mL, against Escherichia coli and Staphylococcus aureus. Cell membrane integrity, electric conductivity and NPN uptake tests showed that ...
DOI:
10.1016/j.carbpol.2016.04.098

11. 3-Diethylaminopropyl-bearing glycol chitosan as a protein drug carrier

Author:
Hye Jung Baik; Nam Muk Oh; Young Taik Oh; Na Young Yoo; So Young Park; Kyung Taek Oh; Yu Seok Youn; Eun Seong Lee
Source:
Colloids and surfaces 2011 v.84 no.2 pp. 585-590
ISSN:
0927-7765
Subject:
blood circulation; bovine serum albumin; chitosan; colloids; drug carriers; mice; models; molecular weight
Abstract:
... Polysaccharidic nanogels were fabricated with bovine serum albumin (BSA) and a glycol chitosan (GCS) grafted with functional 3-diethylaminopropyl (DEAP) groups. These nanogels were investigated to evaulate their cellular uptake in HeLa cells and in vivo fate in nude mice tumor model. Unlike free BSA, GCS-g-DEAP/BSA nanogels improved cellular uptake of BSA. Furthermore, this system led to an enhanc ...
DOI:
10.1016/j.colsurfb.2011.01.017

12. 3-Dimensional porous nanocomposite scaffolds based on cellulose nanofibers for cartilage tissue engineering: tailoring of porosity and mechanical performance

Author:
Narges Naseri; Jean-Michel Poirier; Lenart Girandon; Mirjam Fröhlich; Kristiina Oksman; Aji P. Mathew
Source:
RSC advances 2016 v.6 no.8 pp. 5999-6007
ISSN:
2046-2069
Subject:
cartilage; cellulose nanofibers; chitosan; chondrocytes; chondrogenesis; computed tomography; crosslinking; extracellular matrix; freeze drying; gelatin; mechanical properties; nanocomposites; phosphates; porosity; roughness; scanning electron microscopy; tissue engineering
Abstract:
... Fully bio-based 3-dimensional porous scaffolds based on freeze-dried cellulose nanofibers (70–90 wt%) stabilized using a genipin crosslinked matrix of gelatin and chitosan were prepared. Morphology studies using scanning electron microscopy showed that the scaffolds have interconnected pores with average pore diameters of 75–200 μm and nanoscaled pore wall roughness, both favorable for cell intera ...
DOI:
10.1039/c5ra27246g

13. 3-Formylindole-based chitosan Schiff base polymer: Antioxidant and in vitro cytotoxicity studies on THP-1 cells

Author:
M. Ameer Ali; Shazia Anjum Musthafa; Ganesh Munuswamy-Ramanujam; V. Jaisankar
Source:
Carbohydrate polymers 2022 v.290 pp. 119501
ISSN:
0144-8617
Subject:
Candida albicans; Escherichia coli; Staphylococcus aureus; antioxidant activity; biocompatible materials; cell viability; chitosan; cytotoxicity; flow cytometry; humans; imines; leukemia; monocytes; polymers; reactive oxygen species; schiff bases
Abstract:
... Two imine derivatives of chitosan (i-CTs), namely 2FCT and 5MCT, were synthesized by reacting chitosan (CT) with 2-(3-formyl-1H-indol-1yl)acetonitrile (2F), and 5-methoxyindole-3-carbaldehyde (5M), respectively. The antimicrobial evaluation of i-CTs exhibited stronger inhibition effect against Staphylococcus aureus, Escherichia coli and Candida albicans. The antioxidant activity of 2FCT and 5MCT s ...
DOI:
10.1016/j.carbpol.2022.119501

14. 3D Printing of dynamic tissue scaffold by combining self-healing hydrogel and self-healing ferrogel

Author:
Youngtae Choi; Choonggu Kim; Hyun Seung Kim; Changwook Moon; Kuen Yong Lee
Source:
Colloids and surfaces 2021 v.208 pp. 112108
ISSN:
0927-7765
Subject:
adipic acid; cell structures; chitosan; cytotoxicity; extrusion; hyaluronic acid; hydrogels; iron oxides; magnetic fields; oxidation
Abstract:
... Hydrogels have been widely utilized in tissue engineering applications as functional and biological synthetic extracellular matrices (ECMs) can be created with gels. However, typical hydrogels cannot be exploited in 3D printing, especially in extrusion printing, unless post-cross-linking after printing is provided. Additionally, dynamic tissue scaffolds that can mimic ECM environments in the body ...
DOI:
10.1016/j.colsurfb.2021.112108

15. 3D bacterial cellulose-chitosan-alginate-gelatin hydrogel scaffold for cartilage tissue engineering

Author:
Phasuwit P. Phatchayawat; Arnon Khamkeaw; Supansa Yodmuang; Muenduen Phisalaphong
Source:
Biochemical engineering journal 2022 v.184 pp. 108476
ISSN:
1369-703X
Subject:
Fourier transform infrared spectroscopy; alginates; aqueous solutions; biocompatibility; biopolymers; calcium chloride; cartilage; cell proliferation; cellulose; chitosan; collagen; compression strength; crosslinking; gelatin; glycosaminoglycans; hydrogels; slurries
Abstract:
... Biopolymers of bacterial cellulose, chitosan, alginate and gelatin were combined to fabricate three-dimensional (3D) hydrogel scaffolds for tissue engineering applications. A suitable hydrogel material was fabricated by thoroughly mixing bacterial cellulose-chitosan slurry (BCC) with the mixed solution of alginate and gelatin (AG) at the weight ratio of BCC:AG at 80:20 and crosslinking in the aque ...
DOI:
10.1016/j.bej.2022.108476

16. A 3D bioprinted decellularized extracellular matrix/gelatin/quaternized chitosan scaffold assembling with poly(ionic liquid)s for skin tissue engineering

Author:
Jie Xu; Huan Fang; Ya Su; Yue Kang; Deli Xu; Yuen Yee Cheng; Yi Nie; Hong Wang; Tianqing Liu; Kedong Song
Source:
International journal of biological macromolecules 2022 v.220 pp. 1253-1266
ISSN:
0141-8130
Subject:
Escherichia coli; antibacterial properties; bacterial infections; biocompatibility; biodegradation; bioprinting; cell growth; chitosan; extracellular matrix; extrusion; gelatin; hemolysis; hemostasis; hydrogen; hydrophilicity; ionic liquids; porosity; secretion
Abstract:
... Currently, a suitable bioink for 3D bioprinting and capable of mimicking the microenvironment of native skin and preventing bacterial infection remains a major challenge in skin tissue engineering. In this study, we prepared a tissue-specific extracellular matrix-based bioink, and dECM/Gel/QCS (dGQ) 3D scaffold assembling with poly(ionic liquid)s (PILs) (dGQP) was obtained by an extrusion 3D biopr ...
DOI:
10.1016/j.ijbiomac.2022.08.149

17. 3D bioprinted multiscale composite scaffolds based on gelatin methacryloyl (GelMA)/chitosan microspheres as a modular bioink for enhancing 3D neurite outgrowth and elongation

Author:
Jiali Chen; Da Huang; Ling Wang; Juedong Hou; Hongwu Zhang; Yanbing Li; Shizhen Zhong; Yanfang Wang; Yaobin Wu; Wenhua Huang
Source:
Journal of colloid and interface science 2020 v.574 pp. 162-173
ISSN:
0021-9797
Subject:
Schwann cells; biomimetics; cell proliferation; chitosan; coculture; gelatin; hydrogels; microparticles; nerve tissue; neurites; peripheral nerves; three-dimensional printing; tissue engineering; tissue repair
Abstract:
... The integration of multiscale micro- and macroenvironment has been demonstrated as a critical role in designing biomimetic scaffolds for peripheral nerve tissue regeneration. While it remains a remarkable challenge for developing a biomimetic multiscale scaffold for enhancing 3D neuronal maturation and outgrowth. Herein, we present a 3D bioprinted multiscale scaffold based on a modular bioink for ...
DOI:
10.1016/j.jcis.2020.04.040

18. 3D bioprinted neural tissue constructs for spinal cord injury repair

Author:
Xiaoyun Liu; Mingming Hao; Zhongjin Chen; Ting Zhang; Jie Huang; Jianwu Dai; Zhijun Zhang
Source:
Biomaterials 2021 v.272 pp. 120771
ISSN:
0142-9612
Subject:
animal injuries; axons; biocompatible materials; bioprinting; cell viability; chitosan; crosslinking; gelation; hyaluronic acid; medicine
Abstract:
... Three-dimensional (3D) bioprinting has emerged as a promising approach to fabricate living neural constructs with anatomically accurate complex geometries and spatial distributions of neural stem cells (NSCs) for spinal cord injury (SCI) repair. The NSC-laden 3D bioprinting, however, still faces some big challenges, such as cumbersome printing process, poor cell viability, and minimal cell-materia ...
DOI:
10.1016/j.biomaterials.2021.120771

19. 3D composites based on the blends of chitosan and collagen with the addition of hyaluronic acid

Author:
Alina Sionkowska; Beata Kaczmarek; Katarzyna Lewandowska; Sylwia Grabska; Marta Pokrywczyńska; Tomasz Kloskowski; Tomasz Drewa
Source:
International journal of biological macromolecules 2016 v.89 pp. 442-448
ISSN:
0141-8130
Subject:
chitosan; collagen; fibroblasts; freeze drying; hyaluronic acid; mechanical properties; scanning electron microscopy; thermal stability
Abstract:
... 3D porous composites based on blends of chitosan, collagen and hyaluronic acid were obtained through the lyophilization process. Mechanical properties, swelling behavior and thermal stability of the blends were studied. Moreover, SEM images were taken and the structure of the blends was studied. Biological properties of the materials obtained were investigated by analyzing of proliferation rate of ...
DOI:
10.1016/j.ijbiomac.2016.04.085

20. 3D hierarchical nitrogen-doped carbon nanoflower derived from chitosan for efficient electrocatalytic oxygen reduction and high performance lithium–sulfur batteries

Author:
D. Guo; H. Wei; X. Chen; M. Liu; F. Ding; Z. Yang; Y. Yang; S. Wang; K. Yang; S. Huang
Source:
Journal of materials chemistry A 2017 v.5 no.34 pp. 18193-18206
ISSN:
2050-7496
Subject:
batteries; carbon; catalysts; cathodes; chitosan; durability; electrochemistry; energy; methanol; nanoflowers; nitrogen; oxygen; silica; sulfur; surface area
Abstract:
... Despite diverse carbon materials being intensively applied in energy storage and conversion, efficient optimization of the carbon structure to further improve its performance is still a great challenge. Herein, we design and fabricate a highly uniform 3D hierarchical N-doped carbon nanoflower (NCNF) using low-cost chitosan as the nitrogen and carbon source by a silica template method. The as-prepa ...
DOI:
10.1039/c7ta04728b

21. A 3D hydrogel based on chitosan and carbon dots for sensitive fluorescence detection of microRNA-21 in breast cancer cells

Author:
Susan Mohammadi; Somayeh Mohammadi; Abdollah Salimi
Source:
Talanta 2021 v.224 pp. 121895
ISSN:
0039-9140
Subject:
DNA; benzaldehyde; bioactive compounds; bioassays; biosensors; breast neoplasms; carbon quantum dots; cell viability; chitosan; cytotoxicity; detection limit; fluorescence; fluorescence emission spectroscopy; glutaraldehyde; hydrogels; image analysis; imines; nanocomposites; neoplasm cells; polymers; scanning electron microscopes; schiff bases; transmission electron microscopy; ultraviolet-visible spectroscopy; water
Abstract:
... Hydrogels are 3D polymeric networks with great swelling capability in water and appropriate chemical, mechanical and biological features which make it feasible to maintain bioactive substances. Herein, we fabricated carbon dots-chitosan nanocomposite hydrogels via reacting carbon dots synthesized from various aldehyde precursors with chitosan after that functionalized with ssDNA probe for detectio ...
DOI:
10.1016/j.talanta.2020.121895

22. 3D interconnected boron- and nitrogen-codoped carbon nanosheets decorated with manganese oxides for high-performance capacitive deionization

Author:
Zhengzheng Xie; Xiaohong Shang; Jianmao Yang; Bin Hu; Pengfei Nie; Wenwen Jiang; Jianyun Liu
Source:
Carbon 2020 v.158 pp. 184-192
ISSN:
0008-6223
Subject:
X-ray photoelectron spectroscopy; active sites; adsorption; boric acid; boron; capacitance; carbon; chitosan; deionization; desalination; hydrogels; manganese; manganese dioxide; nanosheets; nitrogen
Abstract:
... The boron- and nitrogen-codoped 3D interconnected carbon nanosheets were synthesized with chitosan hydrogel and boric acid as precursors. The obtained nanosheets were interconnected to form a 3D network with thin lamellae (thickness ∼30 nm) and abundant meso-pores. The successful doping of boron and nitrogen atoms was proved by X-ray photoelectron spectroscopy (XPS). Following the decoration of ma ...
DOI:
10.1016/j.carbon.2019.12.004

23. 3D nanoflower-like layered double hydroxide modified quaternized chitosan/polyvinyl alcohol composite anion conductive membranes for fuel cells

Author:
Shujun Zhao; Wen-Chin Tsen; Chunli Gong
Source:
Carbohydrate polymers 2021 v.256 pp. 117439
ISSN:
0144-8617
Subject:
anion exchange; asymmetric membranes; chitosan; ethylene; methanol; nanosheets; permeability; polyvinyl alcohol; strength (mechanics)
Abstract:
... To solve the trade-off problem among ionic conductivity, mechanical and chemical stability of anion exchange membranes (AEMs), quaternized chitosan (QCS) was first prepared and then was blended with polyvinyl alcohol (PVA) to improve mechanical strength of QCS. Afterwards, three-dimensional (3D) hierarchical flower-like layered double hydroxides (LDHs) were prepared via one-pot ethylene glycol-ass ...
DOI:
10.1016/j.carbpol.2020.117439

24. A 3D paper-based enzymatic fuel cell for self-powered, low-cost glucose monitoring

Author:
Christopher Fischer; Arwa Fraiwan; Seokheun Choi
Source:
Biosensors & bioelectronics 2016 v.79 pp. 193-197
ISSN:
0956-5663
Subject:
biosensors; chitosan; electrochemistry; electrodes; energy conversion; fuel cells; glucose; glucose oxidase; monitoring; oxygen; paper
Abstract:
... In this work, we demonstrate a novel low-cost, self-powered paper-based biosensor for glucose monitoring. The device operating mechanism is based on a glucose/oxygen enzymatic fuel cell using an electrochemical energy conversion as a transducing element for glucose monitoring. The self-powered glucose biosensor features (i) a 3D origami paper-based structure for easy system integration onto paper, ...
DOI:
10.1016/j.bios.2015.12.020

25. 3D porous bioadsorbents based on chitosan/alginate/cellulose nanofibers as efficient and recyclable adsorbents of anionic dye

Author:
Amir Mokhtari; Mohammad Sabzi; Hamidreza Azimi
Source:
Carbohydrate polymers 2021 v.265 pp. 118075
ISSN:
0144-8617
Subject:
adsorbents; adsorption; cellulose nanofibers; chitosan; crosslinking; dyes; freeze drying; nanocomposites; pH; remediation; sorption isotherms
Abstract:
... Natural polysaccharides are attractive materials for fabrication of eco-friendly biodsorbents for efficient water remediation. However, scarcity of adsorbents that possess features of high stability and adsorption capacity at various pH conditions, low-cost, eco-friendly, and recycleability at the same time still remains a great challenge. Herein, porous ionically crosslinked biofoams were prepare ...
DOI:
10.1016/j.carbpol.2021.118075

26. 3D porous chitosan-chondroitin sulfate scaffolds promote epithelial to mesenchymal transition in prostate cancer cells

Author:
Kailei Xu; Zi Wang; John A. Copland; Ratna Chakrabarti; Stephen J. Florczyk
Source:
Biomaterials 2020 v.254 pp. 120126
ISSN:
0142-9612
Subject:
biocompatible materials; cadherins; chitosan; chondroitin sulfate; drug resistance; epithelium; extracellular matrix; metastasis; porosity; prognosis; prostatic neoplasms; sulfates; vimentin
Abstract:
... Prostate cancer (PCa) is a common cancer in men that is curable prior to metastasis, when its prognosis worsens. Chondroitin sulfate (CS) is found in the extracellular matrix of normal prostate tissue and PCa, with greater content in metastatic PCa. Biomaterial scaffolds containing CS have yet to be evaluated for tumor microenvironment applications. Three-dimensional porous chitosan-CS (C-CS) scaf ...
DOI:
10.1016/j.biomaterials.2020.120126

27. 3D porous tubular network-structured chitosan-based beads with multifunctional groups: Highly efficient and selective removal of Cu2+

Author:
Songlin Fan; Zhihan Liu; Yixiao Wu; Yanjuan Zhang; Huayu Hu; Zuqiang Huang; Yuben Qin; Jing Liang
Source:
International journal of biological macromolecules 2021 v.171 pp. 17-27
ISSN:
0141-8130
Subject:
adsorbents; adsorption; chitosan; polyethyleneimine; sorption isotherms; synergism; wastewater
Abstract:
... Herein, an effective adsorbent, 3D porous tubular network-structured citric acid-chitosan/Fe/polyethyleneimine beads (CCFPB) with multifunctional active groups and strong selectivity, was prepared for the selective removal of Cu²⁺ from simulated wastewater. Compared with pure chitosan beads (CB), the adsorption capacity of CCFPB for Cu²⁺ was increased by 127 mg g⁻¹ (238%), and the adsorption equil ...
DOI:
10.1016/j.ijbiomac.2020.12.184

28. A 3D printable dynamic nanocellulose/nanochitin self-healing hydrogel and soft strain sensor

Author:
Pejman Heidarian; Saleh Gharaie; Hossein Yousefi; Mariana Paulino; Akif Kaynak; Russell Varley; Abbas Z. Kouzani
Source:
Carbohydrate polymers 2022 v.291 pp. 119545
ISSN:
0144-8617
Subject:
ambient temperature; biocompatibility; cellulose; cellulose nanofibers; chitin; chitosan; crosslinking; hydrogels; hydrogen; imines; tannins
Abstract:
... Presented here is the synthesis of a 3D printable nano-polysaccharide self-healing hydrogel for flexible strain sensors. Consisting of three distinct yet complementary dynamic bonds, the crosslinked network comprises imine, hydrogen, and catecholato-metal coordination bonds. Self-healing of the hydrogel is demonstrated by macroscopic observation, rheological recovery, and compression measurements. ...
DOI:
10.1016/j.carbpol.2022.119545

29. 3D printable self-healing hyaluronic acid/chitosan polycomplex hydrogels with drug release capability

Author:
Sheila Maiz-Fernández; Nagore Barroso; Leyre Pérez-Álvarez; Unai Silván; José Luis Vilas-Vilela; Senentxu Lanceros-Mendez
Source:
International journal of biological macromolecules 2021 v.188 pp. 820-832
ISSN:
0141-8130
Subject:
bioadhesives; biocompatible materials; biodegradation; chitosan; diclofenac; drug delivery systems; electrolytes; hyaluronic acid; hydrogels; rifampicin
Abstract:
... Multifunctional printable biomaterials are at the base of advanced biomedical applications. Chitosan (CHI) and hyaluronic acid (HA) allow the development of polycomplex hydrogels with tailorable properties, including self-healing and controlled drug release. This work correlates and optimizes the mucoadhesive, swelling, biodegradation, mechanical and rheological properties of HA/CHI polycomplex hy ...
DOI:
10.1016/j.ijbiomac.2021.08.022

30. 3D printed PLA enzyme microreactors: Characterization and application for the modification of bioactive compounds

Author:
Elena Gkantzou; Anastasia Skonta; Aliki Tsakni; Angeliki Polydera; Dimitrios Moschovas; Konstantinos Spyrou; Apostolos Avgeropoulos; Dimitrios Gournis; Dimitra Houhoula; Haralambos Stamatis
Source:
Journal of biotechnology 2022 v.350 pp. 75-85
ISSN:
0168-1656
Subject:
Coriolus versicolor; biotechnology; biotransformation; chitosan; laccase; three-dimensional printing
Abstract:
... Process sustainability of biocatalytic processes is significantly empowered with the use of continuous-flow technologies that offer high productivity, minimal wastes and low volumetric consumption. Combining microreactor design with 3D printing technology can broaden the engineering potentials. This work proposes a protocol to modify the surface of 3D-printed PLA scaffolds, based on chitosan depos ...
DOI:
10.1016/j.jbiotec.2022.04.005

31. 3D printed chitosan scaffolds: A new TiO2 support for the photocatalytic degradation of amoxicillin in water

Author:
Laura Bergamonti; Carlo Bergonzi; Claudia Graiff; Pier Paolo Lottici; Ruggero Bettini; Lisa Elviri
Source:
Water research 2019 v.163 pp. 114841
ISSN:
0043-1354
Subject:
Raman spectroscopy; X-ray diffraction; amoxicillin; chitosan; drugs; irradiation; mechanical properties; photocatalysis; photolysis; pollutants; remediation; three-dimensional printing; titanium dioxide; ultraviolet radiation; ultraviolet-visible spectroscopy; wastewater; wastewater treatment
Abstract:
... TiO₂-supported chitosan scaffolds (TiO₂/CS) are here proposed as promising material for wastewater treatment, in particular for the removal of pharmaceutical compounds. TiO₂/CS are tested for the amoxicillin photodegradation under UV/Vis irradiation. Amoxicillin (AMX) is an antibiotic of the beta-lactam family. Due to the release of antibiotics in wastewater and their persistence in the environmen ...
DOI:
10.1016/j.watres.2019.07.008

32. 3D printed chitosan-gelatine hydrogel coating on titanium alloy surface as biological fixation interface of artificial joint prosthesis

Author:
Xiaofang Wu; Siyu Liu; Kai Chen; Fengyan Wang; Cunao Feng; Linmin Xu; Dekun Zhang
Source:
International journal of biological macromolecules 2021 v.182 pp. 669-679
ISSN:
0141-8130
Subject:
Escherichia coli; Staphylococcus aureus; alloys; antimicrobial properties; biocompatibility; cell adhesion; chitosan; gelatin; hydrogels; hydrophilicity; modulus of elasticity; nanosilver; prostheses; strength (mechanics); three-dimensional printing; titanium
Abstract:
... To improve the fixation of the prosthesis-bone interface and to prevent postoperative infection, a novel antimicrobial hydrogel coating is designed as the biological fixation interface of the artificial joint prosthesis. Antimicrobial chitosan (CS) and gelatine (GT) were used as bioinks to print a CS-GT hydrogel coating with reticulated porous structure on the titanium alloy substrate by 3D printi ...
DOI:
10.1016/j.ijbiomac.2021.04.046

33. 3D printed chitosan/polycaprolactone scaffold for lung tissue engineering: hope to be useful for COVID-19 studies

Author:
Farnoush Sadat Rezaei; Ayeh Khorshidian; Farzaneh Mahmoudi Beram; Atefeh Derakhshani; Javad Esmaeili; Aboulfazl Barati
Source:
RSC advances 2021 v.11 no.32 pp. 19508-19520
ISSN:
2046-2069
Subject:
COVID-19 infection; Severe acute respiratory syndrome coronavirus 2; apoptosis; biocompatibility; cell adhesion; cell culture; cell lines; chitosan; computer software; humans; lungs; mechanical properties; mortality; three-dimensional printing; tissue repair
Abstract:
... To prevent or reduce mortality from lung diseases, new biological materials and scaffolds are needed to conduct more accurate research and support lung tissue regeneration. On the other hand, the outbreak of the COVID-19 virus and its targeting of the human lung has caused many deaths worldwide. The main aim of this study was to provide a biologically and mechanically suitable 3D printed scaffold ...
DOI:
10.1039/d1ra03410c

34. 3D printed nanocellulose-based label for fruit freshness keeping and visual monitoring

Author:
Wei Zhou; Zhengguo Wu; Fengwei Xie; Shuwei Tang; Jiawei Fang; Xiaoying Wang
Source:
Carbohydrate polymers 2021 v.273 pp. 118545
ISSN:
0144-8617
Subject:
1-methylcyclopropene; anthocyanins; blueberries; cellulose nanofibers; chitosan; freshness; fruits; litchis; shelf life; spectroscopy; three-dimensional printing
Abstract:
... Food packaging systems with a single function of freshness keeping or monitoring may not be able to meet all practical needs. Herein, cellulose nanofibers (CNF)-based labels with dual functions of fruit freshness keeping and visual monitoring were prepared by coaxial 3D printing. CNF-based ink with blueberry anthocyanin was used to create the shell of fibers, exhibiting high formability and print ...
DOI:
10.1016/j.carbpol.2021.118545

35. 3D printed photoreactor with immobilized graphitic carbon nitride: A sustainable platform for solar water purification

Author:
Qinmin Zheng; Ashlee Aiello; Yoon Sil Choi; Kayla Tarr; Hongchen Shen; David P. Durkin; Danmeng Shuai
Source:
Journal of hazardous materials 2020 v.399 pp. 123097
ISSN:
0304-3894
Subject:
carbon nitride; chitosan; drinking water; graphene; hydrogels; irradiation; lighting; phenol; photocatalysis; photocatalysts; pollutants; slurries; solar collectors; solar radiation; sulfamethoxazole; three-dimensional printing; wastewater treatment; water purification
Abstract:
... Solar-energy-enabled photocatalysis is promising for sustainable water purification. However, photoreactor design, especially immobilizing nano-sized photocatalysts, remains a major barrier preventing industrial-scale application of photocatalysis. In this study, we immobilized photocatalytic graphitic carbon nitride on chitosan to produce g-C₃N₄/chitosan hydrogel beads (GCHBs), and evaluated GCHB ...
DOI:
10.1016/j.jhazmat.2020.123097

36. 3D printing of cell-laden visible light curable glycol chitosan bioink for bone tissue engineering

Author:
Hyun Kyung Chang; Dae Hyeok Yang; Mi Yeon Ha; Hyun Joo Kim; Chun Ho Kim; Sae Hyun Kim; Jae Won Choi; Heung Jae Chun
Source:
Carbohydrate polymers 2022 v.287 pp. 119328
ISSN:
0144-8617
Subject:
adsorption; biocompatible materials; biopolymers; bone formation; bones; cell proliferation; cell viability; chitosan; hemolysis; irradiation; light; riboflavin; three-dimensional printing; water solubility
Abstract:
... Although chitosan is the second most abundant natural polymer on earth, with a wide range of biomaterial applications, its poor water solubility limits general printing process. We selected water-soluble methacrylated glycol chitosan (MeGC) as an alternative and prepared a MeGC-based MG-63 cell-laden bioink for 3D printing using a visible light curing system. Optimal cell-laden 3D printing of MeGC ...
DOI:
10.1016/j.carbpol.2022.119328

37. 3D printing of high-strength chitosan hydrogel scaffolds without any organic solvents

Author:
Luyu Zhou; Hamed Ramezani; Miao Sun; Mingjun Xie; Jing Nie; Shang Lv; Jie Cai; Jianzhong Fu; Yong He
Source:
Biomaterials science 2020 v.8 no.18 pp. 5020-5028
ISSN:
2047-4849
Subject:
aqueous solutions; biocompatibility; biocompatible materials; biodegradability; cell culture; chitosan; compression strength; gelation; hydrogels; rheological properties; temperature; toxicity
Abstract:
... 3D printing of chitosan hydrogels has attracted wide interest because of their excellent biocompatibility, antibacterial activities, biodegradability, zero toxicity and low cost. However, chitosan inks are often involved in toxic and organic solvents. Moreover, the recently reported 3D-printed chitosan scaffolds lack enough strength, thus limiting their use in tissue engineering. Here, we reported ...
DOI:
10.1039/d0bm00896f

38. 3D printing of self-healing ferrogel prepared from glycol chitosan, oxidized hyaluronate, and iron oxide nanoparticles

Author:
Eun Seok Ko; Choonggu Kim; Youngtae Choi; Kuen Yong Lee
Source:
Carbohydrate polymers 2020 v.245 pp. 116496
ISSN:
0144-8617
Subject:
chitosan; drug delivery systems; extrusion; hyaluronic acid; hydrogels; iron oxides; magnetic fields; mechanical damage; nanoparticles; oxidation; polymers; three-dimensional printing; tissue engineering
Abstract:
... Hydrogel systems that show self-healing ability after mechanical damage are receiving increasing attention. However, self-healing hydrogels suitable for biomedical applications are limited owing to complex preparation methods. Furthermore, few studies have demonstrated the self-healing property of ferrogels. In this study, we demonstrated that glycol chitosan (GC) and oxidized hyaluronate (OHA) ca ...
DOI:
10.1016/j.carbpol.2020.116496

39. 3D sponges of chemically functionalized chitosan for potential environmental pollution remediation: biosorbents for anionic dye adsorption and ‘antibiotic-free’ antibacterial activity

Author:
Isadora C. Carvalho; Fernanda G. L. Medeiros Borsagli; Alexandra A. P. Mansur; Cláudia L. Caldeira; Dionei J. Haas; Andrey P. Lage; Virginia S. T. Ciminelli; Herman S. Mansur
Source:
Environmental technology 2021 v.42 no.13 pp. 2046-2066
ISSN:
1479-487X
Subject:
Pseudomonas aeruginosa; Staphylococcus aureus; adsorbents; adsorption; antibacterial properties; antibiotics; biosorbents; chitosan; death; disulfides; dyes; environmental technology; freeze drying; hospitals; hydrogels; hydrogen; hydrophobicity; kinetics; methyl orange; micro-computed tomography; pathogens; pollutants; pollution; polymers; porosity; remediation; sorption isotherms; surface area; toxicity; ultraviolet-visible spectroscopy
Abstract:
... In this work, it was developed three-dimensional (3D) porous hydrogel sponges produced by the freeze-dried process using chitosan polymer functionalized by 11-mercaptoundecanoic acid (MUA). These chitosan-based sponges were used as cationic adsorbents for the removal of anionic methyl orange (MO) dye, simulating a model organic pollutant in aqueous medium. Moreover, these porous 3D constructs were ...
DOI:
10.1080/09593330.2019.1689302

40. 3D systems delivering VEGF to promote angiogenesis for tissue engineering

Author:
Anne des Rieux; Bernard Ucakar; Billy Paul Kaishusha Mupendwa; Didier Colau; Olivier Feron; Peter Carmeliet; Véronique Préat
Source:
Journal of controlled release 2011 v.150 no.3 pp. 272-278
ISSN:
0168-3659
Subject:
angiogenesis; blood vessels; chitosan; dextran; encapsulation; erythrocytes; hydrocolloids; nanoparticles; tissue engineering; tissue repair; vascular endothelial growth factors
Abstract:
... In most cases, vascularization is the first requirement to achieve tissue regeneration. The delivery from implants of angiogenic factors, like VEGF, has been widely investigated for establishing a vascular network within the developing tissue. In this report, we investigated if encapsulation of VEGF in nanoparticles could enhance angiogenesis in vivo as compared to free VEGF when incorporated into ...
DOI:
10.1016/j.jconrel.2010.11.028

41. 3D-macroporous chitosan-based scaffolds with in situ formed Pd and Pt nanoparticles for nitrophenol reduction

Author:
Dmitriy Berillo; Andrew Cundy
Source:
Carbohydrate polymers 2018 v.192 pp. 166-175
ISSN:
0144-8617
Subject:
Fourier transform infrared spectroscopy; adsorption; ambient temperature; catalysts; catalytic activity; chitosan; cryogels; electrostatic interactions; energy-dispersive X-ray analysis; glutaraldehyde; metal ions; models; nanoparticles; nitrogen; p-nitrophenol; palladium; platinum; scanning electron microscopy; transmission electron microscopy
Abstract:
... 3D-macroporous chitosan-based scaffolds (cryogels) were produced via growth of metal-polymer coordinated complexes and electrostatic interactions between oppositely charged groups of chitosan and metal ions under subzero temperatures. A mechanism of reduction of noble metal complexes inside the cryogel walls by glutaraldehyde is proposed, which produces discrete and dispersed noble metal nanoparti ...
DOI:
10.1016/j.carbpol.2018.03.038

42. 3D-printable chitosan/silk fibroin/cellulose nanoparticle scaffolds for bone regeneration via M2 macrophage polarization

Author:
Dinesh K. Patel; Sayan Deb Dutta; Jin Hexiu; Keya Ganguly; Ki-Taek Lim
Source:
Carbohydrate polymers 2022 v.281 pp. 119077
ISSN:
0144-8617
Subject:
animal models; biodegradability; biopolymers; cellulose; chitosan; fibroins; humans; hydrogels; macrophages; skull; spectroscopy
Abstract:
... Biopolymers-induced immune microenvironment exhibited prominent effects on bone regeneration. Osteo-immunomodulatory responses of cellulose nanoparticles incorporated chitosan hydrogel scaffolds have not yet been reported. The objective of this study was to monitor the synergistic effects of silk fibroin and cellulose nanoparticles on the immune-modulatory behavior of chitosan biopolymer scaffolds ...
DOI:
10.1016/j.carbpol.2021.119077

43. 3D-printed chitosan-based scaffolds: An in vitro study of human skin cell growth and an in-vivo wound healing evaluation in experimental diabetes in rats

Author:
Claudio Intini; Lisa Elviri; Jaydee Cabral; Sonya Mros; Carlo Bergonzi; Annalisa Bianchera; Lisa Flammini; Paolo Govoni; Elisabetta Barocelli; Ruggero Bettini; Michelle McConnell
Source:
Carbohydrate polymers 2018 v.199 pp. 593-602
ISSN:
0144-8617
Subject:
animal disease models; biocompatibility; cell culture; cell growth; chitosan; diabetes; fibroblasts; humans; in vitro studies; keratinocytes; rats; skin (animal); staining; tissue repair; toxicity
Abstract:
... The fabrication of porous 3D printed chitosan (CH) scaffolds for skin tissue regeneration and their behavior in terms of biocompatibility, cytocompatibility and toxicity toward human fibroblasts (Nhdf) and keratinocytes (HaCaT), are presented and discussed. 3D cell cultures achieved after 20 and 35 days of incubation showed significant in vitro qualitative and quantitative cell growth as measured ...
DOI:
10.1016/j.carbpol.2018.07.057

44. 3D-printed highly porous and reusable chitosan monoliths for Cu(II) removal

Author:
Dongxing Zhang; Junfeng Xiao; Qiuquan Guo; Jun Yang
Source:
Journal of materials science 2019 v.54 no.8 pp. 6728-6741
ISSN:
0022-2461
Subject:
EDTA (chelating agent); adsorbents; adsorption; chitosan; copper; cost effectiveness; desorption; equations; heavy metals; human health; metal ions; models; moieties; pH; pollution; pollution control; sorption isotherms; surface area; working conditions
Abstract:
... Removal of heavy metal pollution has received considerable research attention due to its severe effects on human health. In the present study, for the first time, a reusable monolithic 3D porous adsorbing filter was fabricated by integrating 3D printing technique with a natural adsorbent (chitosan), which is a low-cost and highly effective solution for heavy metal removal. The –NH₂ and –OH functio ...
DOI:
10.1007/s10853-019-03332-y

45. 4-(Ethoxycarbonyl) phenyl-1-amino-oxobutanoic acid–chitosan complex as a new matrix for silver nanocomposite film: Preparation, characterization and antibacterial activity

Author:
Rohit Srivastava; Dilip K. Tiwari; P.K. Dutta
Source:
International journal of biological macromolecules 2011 v.49 no.5 pp. 863-870
ISSN:
0141-8130
Subject:
Escherichia coli; Fourier transform infrared spectroscopy; Pseudomonas aeruginosa; Staphylococcus aureus; X-ray diffraction; antibacterial properties; bacteria; chitosan; differential scanning calorimetry; nanocomposites; nanosilver; scanning electron microscopy; silver; thermogravimetry
Abstract:
... The present work describes the preparation of new chitosan complex with 4-(ethoxycarbonyl) phenyl-1-amino-oxobutanoic acid (ETHA), as a matrix for silver nanoparticles to obtain a nanocomposite film by solution casing method. The characterization of the prepared nanocomposite film was made by Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), differential scanning calorimetry ...
DOI:
10.1016/j.ijbiomac.2011.07.015

46. A 4arm-PEG macromolecule crosslinked chitosan hydrogels as antibacterial wound dressing

Author:
Jiawei Lu; Yi Chen; Meng Ding; Xiaokun Fan; Jiawei Hu; Yihua Chen; Jie Li; Zhihan Li; Wenyong Liu
Source:
Carbohydrate polymers 2022 v.277 pp. 118871
ISSN:
0144-8617
Subject:
Escherichia coli; Staphylococcus aureus; biocompatibility; chitosan; crosslinking; fibroblasts; hydrogels; mice; polyethylene glycol; tensile strength; water uptake
Abstract:
... In order to develop better wound dressings, a novel chitosan hydrogel (Cn-Nm gel) was designed and fabricated by using aldehyde-4-arm polyethylene glycol (4r-PEG-CHO) to crosslink the chitosan dissolved in alkaline solution, amino-4-arm polyethylene glycol (4r-PEG-NH₂) was chosen as the additive simultaneously. The special dissolution technique and macromolecular crosslinking structure endows the ...
DOI:
10.1016/j.carbpol.2021.118871

47. 5-Fluorouracil monodispersed chitosan microspheres: Microfluidic chip fabrication with crosslinking, characterization, drug release and anticancer activity

Author:
Tianxi He; Wenbin Wang; Benshou Chen; Jiu Wang; Qionglin Liang; Boshui Chen
Source:
Carbohydrate polymers 2020 v.236 pp. 116094
ISSN:
0144-8617
Subject:
antineoplastic activity; chitosan; crosslinking; cytotoxicity; encapsulation; fluorouracil; glutaraldehyde; microparticles; models; neoplasm cells; organ-on-a-chip; tripolyphosphates
Abstract:
... Different size and morphology monodispersed chitosan (CS) microspheres loaded with the anticancer drug of 5-fluorouracil (5-Fu) were prepared by the microfluidic method assisted by a crosslinking unit with crosslinkers of tripolyphosphate (TPP) and glutaraldehyde (GTA). The sizes, morphologies, drug loading, encapsulation efficiency, drug release and cytotoxicity of 5-Fu loaded CS microspheres wer ...
DOI:
10.1016/j.carbpol.2020.116094

48. 5‑Fluorouracil loaded chitosan/polyacrylic acid/Fe3O4 magnetic nanocomposite hydrogel as a potential anticancer drug delivery system

Author:
Mohammad Sadegh Amini-Fazl; Reza Mohammadi; Karim Kheiri
Source:
International journal of biological macromolecules 2019 v.132 pp. 506-513
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; X-ray diffraction; chitosan; colon; drug delivery systems; drug therapy; fluorouracil; hydrogels; magnetism; nanocomposites; neoplasms; scanning electron microscopy; thermogravimetry
Abstract:
... In most cancer treatments, chemotherapy is currently necessary; hence, more attention was devoted to developing new methods for designing drug delivery systems (DDS) with controlled drug release. For this aim, anticancer 5‑fluorouracil (5-FU) drug was loaded into chitosan/polyacrylic acid/Fe3O4 magnetic nanocomposite hydrogel (CS/PAA/Fe3O4) through immersing in the drug solution. The prepared CS/P ...
DOI:
10.1016/j.ijbiomac.2019.04.005

49. 6-Maleimidohexanoic acid-grafted chitosan: A new generation mucoadhesive polymer

Author:
Nitjawan Sahatsapan; Theerasak Rojanarata; Tanasait Ngawhirunpat; Praneet Opanasopit; Prasopchai Tonglairoum
Source:
Carbohydrate polymers 2018 v.202 pp. 258-264
ISSN:
0144-8617
Subject:
Fourier transform infrared spectroscopy; bioadhesives; biocompatibility; chitosan; drug delivery systems; drugs; fibroblasts; gel chromatography; humans; molecular weight; nuclear magnetic resonance spectroscopy; toxicity; toxicity testing
Abstract:
... This study aims to synthesize and evaluate a new generation mucoadhesive polymer, 6-maleimidohexanoic acid-grafted chitosan; MHA-CS, for transmucosal drug delivery compared with a well-known mucoadhesive polymer, Cys-CS. The successful synthesis was confirmed by nuclear magnetic resonance (NMR) spectroscopy and Fourier transform infrared (FT-IR) spectroscopy. Gel permeation chromatography (GPC) wa ...
DOI:
10.1016/j.carbpol.2018.08.119

50. 6-O-Sulfated Chitosan Promoting the Neural Differentiation of Mouse Embryonic Stem Cells

Author:
Ding Kaiguo; Wang Yanyun; Wang Hongwei; Yuan Lin; Tan Min; Shi Xiujuan; Lyu Zhonglin; Liu Yan; Chen Hong
Source:
ACS Applied Materials & Interfaces 2014 v.6 no.22 pp. 20043-20050
ISSN:
1944-8252
Subject:
chemical structure; chitosan; embryonic stem cells; fluorescent antibody technique; glycosaminoglycans; mice; monitoring; nervous system diseases; neurons; polymerase chain reaction; staining; sulfates
Abstract:
... Embryonic stem cells (ESCs) can be induced to differentiate into nerve cells, endowing them with potential applications in the treatment of neurological diseases and neural repair. In this work, we report for the first time that sulfated chitosan can promote the neural differentiation of ESCs. As a type of sulfated glycosaminoglycan analog, sulfated chitosan with well-defined sulfation sites and a ...
DOI:
10.1021/am505628g

51. 8-Hydroxyquinoline based chitosan derived carbohydrate polymer as biodegradable and sustainable acid corrosion inhibitor for mild steel: Experimental and computational analyses

Author:
M. Rbaa; M. Fardioui; Chandrabhan Verma; Ashraf S. Abousalem; M. Galai; E.E. Ebenso; T. Guedira; B. Lakhrissi; I. Warad; A. Zarrouk
Source:
International journal of biological macromolecules 2020 v.155 pp. 645-655
ISSN:
0141-8130
Subject:
8-hydroxyquinoline; Fourier transform infrared spectroscopy; Monte Carlo method; adsorption; biodegradability; chitosan; corrosion; density functional theory; electrochemistry; energy-dispersive X-ray analysis; nuclear magnetic resonance spectroscopy; polymers; scanning electron microscopy; spectral analysis; steel; temperature; ultraviolet-visible spectroscopy
Abstract:
... The present study reports the synthesis, characterization and corrosion inhibition effects of chitosan (CH) and its 5-chloromethyl-8-hydroxyquinoline derivative (CH-HQ) for mild steel in acidic medium. The synthesized CH-HQ was characterized using ¹H NMR and FT-IR spectroscopic methods. Corrosion inhibition efficiencies of CH and CH-HQ were measured using electrochemical and chemical techniques. T ...
DOI:
10.1016/j.ijbiomac.2020.03.200

52. 90-day ad libitum administration toxicity study of oligoglucosamine in F344 rats

Author:
Naito, Y.; Tago, K.; Nagata, T.; Furuya, M.; Seki, T.; Kato, H.; Morimura, T.; Ohara, N.
Source:
Food and chemical toxicology 2007 v.45 no.9 pp. 1575-1587
ISSN:
0278-6915
Subject:
food additives; chitosan; oligosaccharides; glucosamine; toxicity testing; rats; animal models; oral administration; ad libitum feeding; subchronic toxicity; signs and symptoms (animals and humans); blood chemistry; histopathology
DOI:
10.1016/j.fct.2007.02.018

53. In Vitro Bactericidal Effects of Photodynamic Therapy Combined with Four Tetracyclines against Clostridioides difficile KCTC5009 in Planktonic Cultures

Author:
Sung Sook Choi; Hui Yeong Oh; Eui Jin Kim; Hae Kyung Lee; Hyung Keun Kim; Hyun Ho Choi; Sang Woo Kim; Hiun Suk Chae
Source:
Pathogens 2020 v.9 no.4 pp. -
ISSN:
2076-0817
Subject:
Clostridium difficile; DNA damage; antibacterial properties; cell membranes; cell viability; chitosan; disinfection; doxycycline; ethidium; health services; infection; minocycline; pathogens; photochemotherapy; photosensitizing agents; plankton; risk; tigecycline; ultraviolet radiation
Abstract:
... Surface disinfection in health-care facilities is critical to prevent dissemination of Clostridioides difficile (C. difficile). Tetracyclines (TCs) are broad-spectrum antibiotics that are associated with a low risk of development of C. difficile infection (CDI) and are used as photosensitizers (PS) in photodynamic therapy (PDT). We evaluated whether TCs may be useful environme ...
DOI:
10.3390/pathogens9040279

54. AIE-active polymeric micelles based on modified chitosan for bioimaging-guided targeted delivery and controlled release of paclitaxel

Author:
Haohui Shi; Na Liang; Jiyang Liu; Siyi Li; Xianfeng Gong; Pengfei Yan; Shaoping Sun
Source:
Carbohydrate polymers 2021 v.269 pp. 118327
ISSN:
0144-8617
Subject:
antineoplastic activity; biotin; chitosan; cytotoxicity; disulfides; drugs; fluorescence; glutathione; micelles; paclitaxel; polymers
Abstract:
... In this study, a novel polymer based on aggregation-induced emission (AIE) fluorogen, biotin and disulfide bonds modified chitosan (TPE-bi(SS-CS-Bio)) was designed and synthesized. The polymer could self-assemble into micelles in aqueous media and encapsulate paclitaxel (PTX) into the core with high drug loading. Fluorescence study indicated that the micelles exhibited excellent AIE feature with i ...
DOI:
10.1016/j.carbpol.2021.118327

55. AOT reverse micelles as versatile reaction media for chitosan nanoparticles synthesis

Author:
M. Soledad Orellano; Carina Porporatto; Juana J. Silber; R. Darío Falcone; N. Mariano Correa
Source:
Carbohydrate polymers 2017 v.171 pp. 85-93
ISSN:
0144-8617
Subject:
anti-infective agents; chitosan; crosslinking; dispersibility; drugs; glutaraldehyde; light scattering; micelles; nanoparticles; pH; particle size; scanning electron microscopy
Abstract:
... It is known that Chitosan (Ch) can be used in several applications, such as antimicrobial agent or as drug delivery agent. However, being its water dispersibility very low at physiological pH it is necessary to find a way to improve it. One attractive strategy is to synthesize Chitosan Nanoparticles (Ch-NPs). In this work, a versatile method to obtain Ch-NPs with different and controlled sizes, th ...
DOI:
10.1016/j.carbpol.2017.04.074

56. APC targeted micelle for enhanced intradermal delivery of hepatitis B DNA vaccine

Author:
Buddhadev Layek; Lindsey Lipp; Jagdish Singh
Source:
Journal of controlled release 2015 v.207 pp. 143-153
ISSN:
0168-3659
Subject:
CD4-positive T-lymphocytes; antibodies; antigen-presenting cells; antigens; blood serum; chitosan; chronic hepatitis B; clinical trials; death; humoral immunity; liver neoplasms; mannose; mice; micelles; phenylalanine; plasmids; recombinant vaccines; risk; transfection; vaccination
Abstract:
... Chronic hepatitis B is a serious liver disease and puts people at high risk of death from cirrhosis and liver cancer. Although DNA vaccination has been emerged as a potential immunotherapeutic strategy for the treatment of chronic hepatitis B, the efficiencies were not adequate in clinical trials. Here we describe the design, synthesis, and evaluation of mannosylated phenylalanine grafted chitosan ...
DOI:
10.1016/j.jconrel.2015.04.014

57. ATP/Hyals dually responsive core-shell hyaluronan/chitosan-based drug nanocarrier for potential application in breast cancer therapy

Author:
Huaqiang Li; Shuqiang Zhuang; Yang Yang; Fei Zhou; Jianhua Rong; Jianhao Zhao
Source:
International journal of biological macromolecules 2021 v.183 pp. 839-851
ISSN:
0141-8130
Subject:
adenosine triphosphate; adsorption; blood flow; bovine serum albumin; breast neoplasms; cancer therapy; cell culture; chitosan; crosslinking; drugs; fibroblasts; hemolysis; humans; hyaluronic acid; nanocarriers; neoplasm cells; pH; polyethylene; quaternary ammonium compounds; skin (animal)
Abstract:
... The stability of self-assembled drug nanocarriers during blood circulation and the controlled intracellular drug delivery are two challenges in cancer therapy. In this paper, we constructed an adenosine triphosphate (ATP)/hyaluronidase(Hyals) dually responsive core-shell hyaluronan/chitosan-based drug nanocarrier for breast cancer therapy, using SNX-loaded 3-fluoro-4-carboxyphenylboronic acid-conj ...
DOI:
10.1016/j.ijbiomac.2021.05.020

58. Ability of casein hydrolysate-carboxymethyl chitosan conjugates to stabilize a nanoemulsion: Improved freeze-thaw and pH stability

Author:
Lixin Wang; Shuangling Zhang; Wenping Jiang; Haiyan Zhao; Juanjuan Fu
Source:
Food hydrocolloids 2020 v.101 pp. 105452
ISSN:
0268-005X
Subject:
ambient temperature; casein; casein hydrolysates; chitosan; droplets; emulsifiers; fluorescence emission spectroscopy; freeze-thaw cycles; glycosylation; hydrocolloids; nanoemulsions; pH stability; particle size; polyacrylamide gel electrophoresis; sodium chloride; transmission electron microscopy; tryptophan
Abstract:
... An oil-in-water (O/W) nanoemulsion stabilized by casein hydrolysates (CHs) and carboxymethyl chitosan (OCC) (CHs-OCC) conjugates was prepared and its stability characteristics were evaluated under environmental conditions. The conjugated reaction between CHs and OCC was easier with a maximum degree of glycosylation (DG) of 40.7% and a browning index (BI) of 1.47 were obtained on the 20th day. This ...
DOI:
10.1016/j.foodhyd.2019.105452

59. Ability of selenium species to inhibit metal-induced Aβ aggregation involved in the development of Alzheimer’s disease

Author:
David Vicente-Zurdo; Iván Romero-Sánchez; Noelia Rosales-Conrado; María Eugenia León-González; Yolanda Madrid
Source:
Analytical and bioanalytical chemistry 2020 v.412 no.24 pp. 6485-6497
ISSN:
1618-2642
Subject:
amyloid; analytical chemistry; antioxidant activity; antioxidants; chelation; chitosan; chlorogenic acid; neurodegenerative diseases; peptides; polyphenols; selenium; selenomethionine
Abstract:
... Extracellular accumulation of amyloid beta peptide (Aβ) is believed to be one of the main factors responsible for neurodegeneration in Alzheimer’s disease (AD). Metals could induce Aβ aggregation, by their redox activity or binding properties to amyloid β fibrils, leading to their accumulation and deposition outside neurons. For this reason, metal chelation may have an acknowledged part to play in ...
DOI:
10.1007/s00216-020-02644-2

60. About endothermic sorption of tyrosine on chitosan films

Author:
Eduardo A. Takara; Esteban G. Vega-Hissi; Juan C. Garro-Martinez; José Marchese; Nelio A. Ochoa
Source:
Carbohydrate polymers 2019 v.206 pp. 57-64
ISSN:
0144-8617
Subject:
Fourier transform infrared spectroscopy; adsorption; aqueous solutions; chitosan; crystal structure; differential scanning calorimetry; enantiomers; enantioselectivity; endothermy; energy balance; hydrogen bonding; molecular dynamics; polymers; thermogravimetry; tyrosine
Abstract:
... Sorption of l- and d-Tyrosine (Tyr) from aqueous solutions on chiral membranes of chitosan (CH) was studied. A high adsorption in the membrane, with a marked enantioselectivity to l-Tyr, was found. Computational calculations carried out by docking and molecular dynamics (MD) showed a difference in the affinity of the enantiomers and two regions of adsorption in the polymer matrix. The interactions ...
DOI:
10.1016/j.carbpol.2018.10.102

61. Abscisic Acid and Chitosan Modulate Polyphenol Metabolism and Berry Qualities in the Domestic White-Colored Cultivar Savvatiano

Author:
Dimitrios Evangelos Miliordos; Anastasios Alatzas; Nikolaos Kontoudakis; Angeliki Kouki; Marianne Unlubayir; Marin-Pierre Gémin; Alexandros Tako; Polydefkis Hatzopoulos; Arnaud Lanoue; Yorgos Kotseridis
Source:
Plants 2022 v.11 no.13 pp. -
ISSN:
2223-7747
Subject:
Vitis; abscisic acid; anthocyanins; biosynthesis; chitosan; cultivars; gene expression; grapes; metabolome; phenology; polyphenols; ripening; stilbenoids; transcription (genetics); viticulture; wine quality
Abstract:
... During the last decade, several studies demonstrated the effect of biostimulants on the transcriptional and metabolic profile of grape berries, suggesting their application as a useful viticultural practice to improve grape and wine quality. Herein, we investigated the impact of two biostimulants—abscisic acid (0.04% w/v and 0.08% w/v) and chitosan (0.3% w/v and 0.6% w/v)—on the polyphenol metabol ...
DOI:
10.3390/plants11131648

62. Abscisic acid, carbohydrate, and Glucosinolate metabolite profiles in Kimchi cabbage treated with extremely high temperatures and chitosan foliar application

Author:
Ha Seon Sim; Jung Su Jo; Ui Jeong Woo; Won Jun Jo; Yu Hyun Moon; Jun Gu Lee; Hee Ju Lee; Seung Hwan Wi; Sung Kyeom Kim
Source:
Scientia horticulturae 2022 v.304 pp. 111311
ISSN:
0304-4238
Subject:
abscisic acid; cabbage; chitosan; foliar application; fructose; glucobrassicin; gluconapin; glucose; heat stress; heat treatment; kimchi; leaves; light intensity; metabolites; phaseic acid; spring; temperature
Abstract:
... Chitosan can help enhance disease resistance in plants by thickening leaves and alleviating environmental stresses, such as excess light intensity and extremely high temperature by promoting physiological activity. This study evaluated the effects of chitosan foliar application on Kimchi cabbage under high temperature stress. Six treatments were conducted, combining three photo-/dark periods tempe ...
DOI:
10.1016/j.scienta.2022.111311

63. Absorbent alginate fibres modified with hydrolysed chitosan for wound care dressings – II. Pilot scale development

Author:
I.R. Sweeney; M. Miraftab; G. Collyer
Source:
Carbohydrate polymers 2014 v.102 pp. 920-927
ISSN:
0144-8617
Subject:
absorption; anti-infective properties; chitosan; extrusion; hardness; hydrolysis; staining; surface area; tensile strength
Abstract:
... Fibres have been used extensively in wound dressing applications as they provide a high surface area for absorption, ease of fabrication and softness. It is common practice for commercial wound dressings to be produced from natural materials, such a marine polysaccharides, as they are predominantly biocompatible, non-toxic, and often display bioactive properties, such as inherent antimicrobial act ...
DOI:
10.1016/j.carbpol.2013.10.053

64. Absorption Behavior of Metal Ions on Chitin/Cellulose Composite Fibers with Chemical Modification by EDTA

Author:
Shinya Izumi; Yoshiaki Shimizu; Toshinobu Higashimura
Source:
Textile research journal 2002 v.72 no.6 pp. 515-519
ISSN:
0040-5175
Subject:
cellulose; chitin; chitosan; synthesis; chemical treatment; dimethyl sulfoxide; metal ions; dyes; absorption; desorption; sorption isotherms; pH; EDTA (chelating agent)
Abstract:
... The novel synthesis of EDTA-modified chitin/cellulose composite fibers is accomplished using dimethyl sulfoxide as the solvent, and the absorptive ability of the fibers for metal ions is examined by measuring absorption isotherms at different pHs. For some metal ions, the modified fibers show improved absorption powers compared with the parent fiber material. These composite fibers may be a reusab ...
DOI:
10.1177/004051750207200609

65. Absorption and distribution of chitosan in mice after oral administration

Author:
Zeng, L.; Qin, C.; Wang, W.; Chi, W.; Li, W.
Source:
Carbohydrate polymers 2008 v.71 no.3 pp. 435-440
ISSN:
0144-8617
Subject:
chitosan; intestinal absorption; molecular weight; water solubility; animal organs; tissue distribution; mice
Abstract:
... Four chitosan samples with different molecular weight Mw and the degree of deacetylation DD (HCS 7.60 x 105 and 85.5%, MCS 3.27 x 104 and 85.2%, COS 0.99 x 103 and 85.7%, WSC 3.91 x 104 and 52.6%) were prepared, and labeled by fluorescein isothiocyanate. These labeled samples were used to investigate the absorption and distribution in mice after oral administration. The results indicated that the ...
DOI:
10.1016/j.carbpol.2007.06.016

66. Absorption and distribution of water-soluble hydroxypropyl chitosan in mice after oral administration

Author:
Zhihua Wang; Yongbin Yan; Wei Li; Lihua Wang; Guoyuan Li; Caiqin Qin
Source:
Bioactive carbohydrates and dietary fibre 2016 v.7 no.1 pp. 21-25
ISSN:
2212-6198
Subject:
absorption; chemical elements; chitosan; dietary fiber; drug delivery systems; fluorescein; isothiocyanates; kidneys; liver; lysozyme; medicine; mice; molecular weight; oral administration; pepsin; tissues
Abstract:
... Two kinds of water-soluble hydroxypropyl chitosan (HPCS) samples with different weight-average molecular weights (Mw) (HHPCS for higher Mw, 1.43×105Da; LHPCS for lower Mw, 5.71×103Da) were used to investigate their absorption and distribution in mice by oral administration after being labeled by fluorescein isothiocyanate. The result of in vitro degradation showed that HPCS degraded more easily in ...
DOI:
10.1016/j.bcdf.2016.01.003

67. Accelerated nerve regeneration using induced pluripotent stem cells in chitin–chitosan–gelatin scaffolds with inverted colloidal crystal geometry

Author:
Yung-Chih Kuo; Ching-Chun Lin
Source:
Colloids and Surfaces B: Biointerfaces 2013 v.103 pp. 595-600
ISSN:
0927-7765
Subject:
adhesion; biocompatible materials; chitin; chitosan; colloids; crosslinking; crystals; ethanol; ethylene glycol; gelatin; induced pluripotent stem cells; nerve tissue; neurons; topography; viability
Abstract:
... Polymeric biomaterials with regular pore structure can generate distinctive properties in various biomedical applications. This study presents scaffolds comprising chitin, chitosan, and gelatin with pore geometry of inverted colloidal crystals (ICC) for guiding differentiation of induced pluripotent stem (iPS) cells toward neurons. Chitin–chitosan–gelatin ICC scaffolds were fabricated by self-asse ...
DOI:
10.1016/j.colsurfb.2012.11.001

68. Accelerated skin wound healing by soy protein isolate–modified hydroxypropyl chitosan composite films

Author:
Yanan Zhao; Zijian Wang; Qiang Zhang; Feixiang Chen; Zhiyi Yue; Tiantian Zhang; Hongbing Deng; Céline Huselstein; Debbie P. Anderson; Peter R. Chang; Yinping Li; Yun Chen
Source:
International journal of biological macromolecules 2018 v.118 pp. 1293-1302
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; X-ray diffraction; biocompatibility; chitosan; composite films; composite materials; crosslinking; evaporation; hemolysis; in vitro studies; mechanical testing; models; physical properties; protein isolates; rats; scanning electron microscopy; soy protein; tensile strength
Abstract:
... In this study, a series of hydroxypropyl chitosan (HPCS)/soy protein isolate (SPI) composite films (HCSFs) with different SPI contents were developed via crosslinking, solution casting, and evaporation process. Effects of the SPI content on the structure and physical properties of the HCSFs were characterized by Fourier transform infrared spectroscopy, X-ray diffraction patterns, scanning electron ...
DOI:
10.1016/j.ijbiomac.2018.06.195

69. Accelerated wound healing and anti-inflammatory effects of physically cross linked polyvinyl alcohol–chitosan hydrogel containing honey bee venom in diabetic rats

Author:
Mohamed A. Amin; Ihab T. Abdel-Raheem
Source:
Archives of pharmacal research 2014 v.37 no.8 pp. 1016-1031
ISSN:
0253-6269
Subject:
Apoidea; animal disease models; anti-inflammatory activity; anti-inflammatory agents; chitosan; crosslinking; diabetes mellitus; gels; glutathione; honey bees; hydrocolloids; hydroxyproline; interleukin-6; pH; polyvinyl alcohol; rats; skin irritation; tensile strength; tissue repair; venoms
Abstract:
... Diabetes is one of the leading causes of impaired wound healing. The objective of this study was to develop a bee venom-loaded wound dressing with an enhanced healing and anti-inflammatory effects to be examined in diabetic rats. Different preparations of polyvinyl alcohol (PVA), chitosan (Chit) hydrogel matrix-based wound dressing containing bee venom (BV) were developed using freeze–thawing meth ...
DOI:
10.1007/s12272-013-0308-y

70. Accelerating Effect of Chitosan Intake on Urinary Calcium Excretion by Rats

Author:
Masahiro Wada; Yoshikazu Nishimura; Yoshito Watanabe; Toshichika Takita; Satoshi Innami
Source:
Bioscience, biotechnology, and biochemistry 1997 v.61 no.7 pp. 1206-1208
ISSN:
1347-6947
Subject:
biotechnology; calcium; cellulose; chitosan; diet; excretion; metabolism
Abstract:
... The effect of chitosan on calcium (⁴⁷Ca) metabolism was investigated in rats. The whole-body retention of ⁴⁷Ca by rats fed on a 5% chitosan diet was significantly decreased when compared with that of rats fed on a cellulose diet, but showed no significant difference from that of rats fed on a fiber-free diet. Although there was no significant difference in the fecal excretion of ⁴⁷Ca between the c ...
DOI:
10.1271/bbb.61.1206

71. Acceleration of gelation and promotion of mineralization of chitosan hydrogels by alkaline phosphatase

Author:
Timothy E.L. Douglas; Agata Skwarczynska; Zofia Modrzejewska; Lieve Balcaen; David Schaubroeck; Sylvia Lycke; Frank Vanhaecke; Peter Vandenabeele; Peter Dubruel; John A. Jansen; Sander C.G. Leeuwenburgh
Source:
International journal of biological macromolecules 2013 v.56 no. pp. 122-132
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; Raman spectroscopy; X-ray diffraction; alkaline phosphatase; body temperature; bone mineralization; bone substitutes; calcium phosphates; chitosan; gelation; glycerophosphates; hydrocolloids; mineralization; molecular weight; scanning electron microscopy
Abstract:
... Thermosensitive chitosan hydrogels containing sodium beta-glycerophosphate (β-GP), whose gelation is induced by increasing temperature to body temperature, were functionalized by incorporation of alkaline phosphatase (ALP), an enzyme involved in mineralization of bone. ALP incorporation led to acceleration of gelation upon increase of temperature for four different chitosan preparations of differi ...
DOI:
10.1016/j.ijbiomac.2013.02.002

72. Acceleration of wound healing in diabetic rats by layered hydrogel dressing

Author:
Yen-Hsien Lee; Jung-Jhih Chang; Ming-Chien Yang; Chiang-Ting Chien; Wen-Fu Lai
Source:
Carbohydrate polymers 2012 v.88 no.3 pp. 809-819
ISSN:
0144-8617
Subject:
blood coagulation; tissue repair; cell movement; chitosan; calcium; diabetes mellitus; hydrocolloids; collagen; hydroxyproline; in vitro studies; rats; water vapor; animal disease models
Abstract:
... In this study, a novel layered hydrogel composing of alginate (AL), chitosan (CS), and poly(γ-glutamic acid) (PGA) was prepared. The resulting hydrogel was characterized, including the swelling ratio, water vapor transmission rate, the release of Ca²⁺ and blood coagulation activity. In vitro evaluation of cell migration and proliferation were carried out on electric cell-substrate impedance sensin ...
DOI:
10.1016/j.carbpol.2011.12.045

73. Accelerative effect of nanohydrogels based on chitosan/ZnO incorporated with citral to heal the infected full-thickness wounds; an experimental study

Author:
Omidreza Raei Abbasabadi; Mohammad Reza Farahpour; Zohreh Ghazi Tabatabaei
Source:
International journal of biological macromolecules 2022 v.217 pp. 42-54
ISSN:
0141-8130
Subject:
antibacterial properties; antibiotic resistance; chitosan; citral; fluorescent antibody technique; ointments; plate count; toxicity; zinc oxide
Abstract:
... Antimicrobial-resistant is a major challenge in to treat infected wounds, and new formulations should be produced. Citral (Citl), chitosan (Chsn), and zinc oxide (ZnO) nanoparticles may accelerate the wound healing process in terms of their antibacterial properties. This new study aimed to investigate the effects of ointments produced from ZnO/Chsn/Citl nanoparticles (NPs) to treat the infected wo ...
DOI:
10.1016/j.ijbiomac.2022.07.038

74. Access to cross-linked chitosans by exploiting CO₂ and the double solvent-catalytic effect of ionic liquids

Author:
Andrea Mezzetta; Lorenzo Guazzelli; Cinzia Chiappe
Source:
Green chemistry 2017 v.19 no.5 pp. 1235-1239
ISSN:
1463-9270
Subject:
biopolymers; carbon dioxide; chitosan; cross-linking reagents; crosslinking; green chemistry; greenhouse gases; ionic liquids; liquids
Abstract:
... Unreported ureido cross-linked chitosans were obtained employing the CO₂–chitosan–ionic liquid three component system. Under the conditions used, the greenhouse gas functions as a safe cross-linking agent of the biopolymer thanks to the solvent-catalytic effect of [bmim][OAc]. ...
DOI:
10.1039/c6gc02935c

75. Access to tough and transparent nanocomposites via Pickering emulsion polymerization using biocatalytic hybrid lignin nanoparticles as functional surfactants

Author:
Adrian Moreno; Mohammad Morsali; Jinrong Liu; Mika H. Sipponen
Source:
Green chemistry 2021 v.23 no.8 pp. 3001-3014
ISSN:
1463-9270
Subject:
antioxidants; chitosan; emulsions; free radicals; glucose oxidase; green chemistry; latex; lignin; polymer nanocomposites; polymerization; polystyrenes; tensile strength
Abstract:
... Weak interfacial binding of lignin within synthetic polymer composites results in unsatisfactory mechanical properties that limit their application prospects. In the present work, polystyrene (PS) and poly(butyl methacrylate) (PBMA) nanocomposites containing lignin nanoparticles (LNPs) are produced by simple melting of polymeric latex dispersions obtained from free radical polymerization of oil-in ...
DOI:
10.1039/d1gc00103e

76. Accessibility of chitin and chitosan in enzymatic hydrolysis: A review

Author:
Daria N. Poshina; Sergei V. Raik; Alexander N. Poshin; Yury A. Skorik
Source:
Polymer degradation and stability 2018 v.156 pp. 269-278
ISSN:
0141-3910
Subject:
carboxylic ester hydrolases; cellulose; chitin; chitinase; chitooligosaccharides; chitosan; cost effectiveness; crystal structure; enzymatic hydrolysis; enzymatic treatment; hydrolysis; mechanism of action; polymers; proteinases
Abstract:
... The enzymatic modification of polysaccharides has attracted much research attention, as it raises the possibility of using highly selective reactions performed by naturally designed proteins for practical purposes. However, achieving high performance of enzymes for the degradation of insoluble natural polysaccharides with highly ordered structures, such as cellulose and chitin, remains challenging ...
DOI:
10.1016/j.polymdegradstab.2018.09.005

77. Accessory active site residues of Streptomyces sp. N174 chitosanase

Author:
Lacombe-Harvey, Marie-Ève; Fukamizo, Tamo; Gagnon, Julie; Ghinet, Mariana G.; Dennhart, Nicole; Letzel, Thomas; Brzezinski, Ryszard
Source:
FEBS journal 2009 v.276 no.3 pp. 857-869
ISSN:
1742-464X
Subject:
Escherichia coli; Streptomyces; active sites; anti-infective properties; catalytic activity; chitinase; chitosan; chitosanase; glycosides; heterologous gene expression; lysozyme; mutagenesis; serine
Abstract:
... The chitosanase from Streptomyces sp. N174 (CsnN174) is an inverting glycoside hydrolase belonging to family 46. Previous studies identified Asp40 as the general base residue. Mutation of Asp40 into glycine revealed an unexpectedly high residual activity. D40G mutation did not affect the stereochemical mechanism of catalysis or the mode of interaction with substrate. To explain the D40G residual a ...
DOI:
10.1111/j.1742-4658.2008.06830.x

78. Accumulation and depuration of paralytic shellfish poisoning toxins in the oyster Ostrea rivularis Gould – Chitosan facilitates the toxin depuration

Author:
Wancui Xie; Xiaoli Liu; Xihong Yang; Chaohua Zhang; Zhongyuan Bian
Source:
Food control 2013 v.30 no.2 pp. 446-452
ISSN:
0956-7135
Subject:
Alexandrium minutum; Chlorella; Ostrea; bioassays; chitosan; fluorescence; high performance liquid chromatography; laboratory experimentation; mice; microalgae; oxidation; oysters; paralytic shellfish poisoning; poisoning; toxicity; toxins
Abstract:
... The accumulation and depuration of paralytic shellfish poisoning (PSP) toxins in the oyster of Ostrea rivularis Gould (ORG) were investigated in this study. Firstly, PSP toxin-accumulating in ORG were produced by feeding with the toxic algae Alexandrium minutum cultured in the laboratory. The feeding amounts were designed for three concentrations of 4.0 × 103, 8.0 × 103, and 1.2 × 104 cells/mL. Af ...
DOI:
10.1016/j.foodcont.2012.07.035

79. Accumulation of 2-Acetylamino-5-mercapto-1,3,4-thiadiazole in chitosan coatings for improved anticorrosive effect on zinc

Author:
Árpád Ferenc Szőke; Gabriella Stefánia Szabó; Zoltán Hórvölgyi; Emőke Albert; Attila Gergely Végh; László Zimányi; Liana Maria Muresan
Source:
International journal of biological macromolecules 2020 v.142 pp. 423-431
ISSN:
0141-8130
Subject:
atomic force microscopy; chitosan; coatings; corrosion; dielectric spectroscopy; glass; polymers; quartz; ultraviolet-visible spectroscopy; zinc
Abstract:
... Chitosan (Chit) coatings were applied on zinc substrates by the dip-coating method. Subsequently, the coatings were impregnated with a corrosion inhibitor, 2-Acetylamino-5-mercapto-1,3,4-thiadiazole (AcAMT) to obtain an increased anticorrosive effect. The coating thickness and the AcAMT accumulation were determined using UV–Vis spectroscopy on glass and quartz substrates, respectively. The surface ...
DOI:
10.1016/j.ijbiomac.2019.09.114

80. Accumulation of Copper in Gill, Liver, Spleen, Kidney and Muscle Tissues of Clarias gariepinus Exposed to the Metal Singly and in Mixture with Chitosan

Author:
Mustafa Tunçsoy; Servet Duran; Özcan Ay; Bedii Cicik; Cahit Erdem
Source:
Bulletin of environmental contamination and toxicology 2016 v.97 no.4 pp. 486-489
ISSN:
0007-4861
Subject:
Clarias gariepinus; chitosan; copper; exposure duration; fish; gills; kidneys; liver; mortality; muscle tissues; spectrophotometers; spleen
Abstract:
... Accumulation of copper (Cu), applied singly and in mixture with chitosan (CT), in gill, liver, spleen, kidney and muscle tissues of Clarias gariepinus was studied after exposing the fish to no Cu (control), 5 ppm Cu, 5 ppm Cu + 75 ppm CT mixture over 1, 7 and 15 days. Metal levels in tissues were determined using an ICP-AES spectrophotometer. No mortality was observed during the experiments. Highe ...
DOI:
10.1007/s00128-016-1900-x

81. Accumulation of conjugated linoleic acid in Lactobacillus plantarum WU-P19 is enhanced by induction with linoleic acid and chitosan treatment

Author:
Wilawan Palachum; Wanna Choorit; Yusuf Chisti
Source:
Annals of microbiology 2018 v.68 no.10 pp. 611-624
ISSN:
1590-4261
Subject:
Lactobacillus plantarum; bacteria; biomass; chitosan; conjugated linoleic acid; culture media; food intake; pH; probiotics
Abstract:
... Production of conjugated linoleic acid (CLA) by the potential probiotic bacterium Lactobacillus plantarum WU-P19 was investigated with the aim of enhancing production. CLA produced using this bacterium may be used to supplement dietary intake. Cultures were fed linoleic acid for conversion to CLA and the CLA produced was measured. In some cases, chitosan was added to cultures to improve cellular u ...
DOI:
10.1007/s13213-018-1368-5

82. Accumulation of phenylpropanoid derivatives in chitosan-induced cell suspension culture of Cocos nucifera

Author:
Chakraborty, Moumita; Karun, Anitha; Mitra, Adinpunya
Source:
Journal of plant physiology 2009 v.166 no.1 pp. 63-71
ISSN:
0176-1617
Subject:
Cocos nucifera; endosperm; plant response; physiological response; phenylpropanoids; chitosan; cell suspension culture; cultured cells; 4-hydroxybenzoic acid; peroxidases; phenylalanine ammonia-lyase; coumarate-CoA ligase; enzyme activity; phenols
Abstract:
... Chitosan-induced elicitation responses of dark-incubated Cocos nucifera (coconut) endosperm cell suspension cultures led to the rapid formation of phenylpropanoid derivatives, which essentially mimics the defense-induced biochemical changes in coconut palm as observed under in vivo conditions. An enhanced accumulation of p-hydroxybenzoic acid as the major wall-bound phenolics was evident. This was ...
DOI:
10.1016/j.jplph.2008.02.004

83. Accurate data prediction by fuzzy inference model for adsorption of hazardous azo dyes by novel algal doped magnetic chitosan bionanocomposite

Author:
Swati Solanki; Surbhi Sinha; Kavya Bisaria; Rachana Singh; Reena Saxena
Source:
Environmental research 2022 v.214 pp. 113844
ISSN:
0013-9351
Subject:
Fourier transform infrared spectroscopy; X-ray diffraction; adsorbents; adsorption; algae; chitosan; data collection; energy-dispersive X-ray analysis; fuzzy logic; habitats; magnetism; model validation; nanocomposites; pH; prediction; research; temperature; toxicity
Abstract:
... A bionanocomposite comprising of magnetic chitosan doped with algae isolated from native habitat was fabricated and utilized as an efficient adsorbent for the removal of hazardous azo dyes, namely, Direct Red 31 (DR31) and Direct Red 28 (DR28). The algal doped magnetic chitosan (Alg@mCS) was comprehensively characterized by Scanning Electron Microscopy (SEM), Energy Dispersive X-Ray Analysis (EDAX ...
DOI:
10.1016/j.envres.2022.113844

84. Accurate fish-freshness prediction label based on red cabbage anthocyanins

Author:
Shuliang Fang; Zhihao Guan; Cheng Su; Wenshuo Zhang; Jian Zhu; Yuewei Zheng; Houbin Li; Pingping Zhao; Xinghai Liu
Source:
Food control 2022 v.138 pp. 109018
ISSN:
0956-7135
Subject:
anthocyanins; cabbage; chitosan; color; colorimetry; eyes; fish; food quality; food safety; freshness; humans; mobile telephones; oxidation; pH; prediction; quality control; silica; sodium alginate; storage time; supply chain
Abstract:
... Biosafe colorimetric labels that can accurately evaluate food freshness have been widely investigated in recent years. Here, red cabbage anthocyanin labels and back propagation (BP) neural network are combined to form a system for monitoring fish freshness. Anthocyanins extracted from red cabbage were used as color response pigments and carboxymethyl chitosan/oxidized sodium alginate (CMCS/OSA) as ...
DOI:
10.1016/j.foodcont.2022.109018

85. Accurate prediction and further dissection of neonicotinoid elimination in the water treatment by CTS@AgBC using multihead attention-based convolutional neural network combined with the time-dependent Cox regression model

Author:
Chao Zhang; Xiaoyong Li; Feng Li; Gugong Li; Guoqiang Niu; Hongyu Chen; Guang-Guo Ying; Mingzhi Huang
Source:
Journal of hazardous materials 2022 v.423 pp. 127029
ISSN:
0304-3894
Subject:
adsorption; biochar; chitosan; dissection; ecosystems; imidacloprid; nanosilver; neural networks; pH; prediction; regression analysis; temperature; water treatment
Abstract:
... Imidacloprid (IMI), as the most widely used neonicotinoid insecticide, poses a serious threat to the water ecosystem due to the inefficient elimination in the traditional water treatment. Chitosan (CTS)-stabilized biochar (BC)-supported Ag nanoparticles (CTS@AgBC) are applied to eliminate the IMI in the water treatment effectively. Batch experiments depict that the modification of BC by CTS and Ag ...
DOI:
10.1016/j.jhazmat.2021.127029

86. Acetic acid acts as an elicitor exerting a chitosan-like effect on xanthone biosynthesis in Hypericum perforatum L. root cultures

Author:
Alessio Valletta; Giulia De Angelis; Camilla Badiali; Elisa Brasili; Alfredo Miccheli; Maria Enrica Di Cocco; Gabriella Pasqua
Source:
Plant cell reports 2016 v.35 no.5 pp. 1009-1020
ISSN:
0721-7714
Subject:
Hypericum perforatum; acetic acid; biosynthesis; butyric acid; carbon; chitosan; culture media; elicitors; isotope labeling; roots; skeleton; solubilization; solvents; stable isotopes; xanthone
Abstract:
... KEY MESSAGE : Acetic acid acts as a signal molecule, strongly enhancing xanthone biosynthesis in Hypericum perforatum root cultures. This activity is specific, as demonstrated by the comparison with other short-chain monocarboxylic acids. We have recently demonstrated that Hypericum perforatum root cultures constitutively produce xanthones at higher levels than the root of the plant and that they ...
DOI:
10.1007/s00299-016-1934-x

87. Acetic acid transporter-mediated, oral, multifunctional polymer liposomes for oral delivery of docetaxel

Author:
XinHong Guo; JunYa Zhang; QingQing Cai; ShuTing Fan; QingQing Xu; JieYing Zang; HuiTing Yang; WenJuan Yu; Zhi Li; ZhenZhong Zhang
Source:
Colloids and surfaces 2021 v.198 pp. 111499
ISSN:
0927-7765
Subject:
acetic acid; bioavailability; blood; chitosan; dithiothreitol; drug delivery systems; drugs; growth retardation; hydrophilicity; hydrophobicity; lipoic acid; neoplasms; pH; polymers; toxicity; weight loss
Abstract:
... Nanoparticle-structuring aimed at the acetic acid (A) transporter on intestinal epithelial cells and tumor cells is a new potential strategy to enhance oral bioavailability and anti-tumor efficacy. In this study, chitosan (CS) was modified with hydrophilic A and hydrophobic lipoic acid (L), to produce ACSL. A novel ACSL-modified multifunctional liposomes (Lip) loaded with docetaxel (DTX; DTX-ACSL- ...
DOI:
10.1016/j.colsurfb.2020.111499

88. Acetyl xylan esterase-catalyzed deacetylation of chitin and chitosan

Author:
Morley, K.L.; Chauve, G.; Kazlauskas, R.; Dupont, C.; Shareck, F.; Marchessault, R.H.
Source:
Carbohydrate polymers 2006 v.63 no.3 pp. 310-315
ISSN:
0144-8617
Subject:
chitosan; crystal structure; acetylation; esterases; chitin
Abstract:
... Acetyl xylan esterase catalyzes the hydrolysis of N-acetyl groups in chitinous materials of variable degrees of polymerization and acetylation. The influence of substrate accessibility is most notable with substrate of high degree of acetylation (DA). The activity rises sharply as the number of acetyl groups in the substrates decreases and at about 24% DA enzyme activity reaches a maximum. Therefo ...
DOI:
10.1016/j.carbpol.2005.07.034

89. Acetylated Distarch Phosphate/Chitosan Films Reinforced with Sodium Laurate‐Modified Nano‐TiO2: Effects of Sodium Laurate Concentration

Author:
Yuanyuan Wu; Shuai Li; Jingxin Song; Bingxue Jiang; ShanShan Chen; Huimin Sun; Xinxin Li
Source:
Journal of food science 2018 v.83 no.11 pp. 2819-2826
ISSN:
0022-1147
Subject:
Fourier transform infrared spectroscopy; X-ray diffraction; anionic surfactants; biopolymers; chemical bonding; chitosan; composite films; composite materials; dispersibility; hydrophobicity; microwave treatment; nanoparticles; packaging; permeability; phosphates; scanning electron microscopy; tensile strength; titanium dioxide; ultrasonics; water solubility; water vapor
Abstract:
... Nano‐titanium dioxide (TiO₂) was modified with the surfactant sodium laurate (SL) via ultrasonic microwave‐assisted technology to improve the dispersion of TiO₂ in polymer matrices. As revealed by Fourier transform infrared spectroscopy, X‐ray diffraction, and scanning electron microscopy analyses, SL was well adsorbed onto the TiO₂ surface through chemical bonding, resulting in SL‐modified TiO₂ ( ...
DOI:
10.1111/1750-3841.14354

90. Acetylation degree, a key parameter modulating chitosan rheological, thermal and film-forming properties

Author:
Marwa Hamdi; Rim Nasri; Sawssen Hajji; Michaël Nigen; Suming Li; Moncef Nasri
Source:
Food hydrocolloids 2019 v.87 pp. 48-60
ISSN:
0268-005X
Subject:
acetylation; chitosan; crabs; gelatinization temperature; glass transition temperature; heat tolerance; hydrocolloids; industrial applications; modulus of elasticity; tensile strength; thermal stability; thermogravimetry; viscoelasticity; viscosity
Abstract:
... The effect of blue crab chitosan acetylation degree (AD) on its rheological, thermal and film-forming properties was investigated. Determination of the dynamic viscoelastic properties (elastic modulus G’ and viscous modulus G”) of chitosan solutions revealed a typical Newtonian viscous-like behavior, with higher viscosity values at lower acetylation degrees. Moreover, the gelation temperature of b ...
DOI:
10.1016/j.foodhyd.2018.07.027

91. Acetylcholinesterase biosensor based on SnO2 nanoparticles–carboxylic graphene–nafion modified electrode for detection of pesticides

Author:
Qing Zhou; Long Yang; Guangcan Wang; Yun Yang
Source:
Biosensors & bioelectronics 2013 v.49 pp. 25-31
ISSN:
0956-5663
Subject:
Fourier transform infrared spectroscopy; X-ray diffraction; acetylcholinesterase; adhesion; biocompatibility; biosensors; carbofuran; catalytic activity; chitosan; detection limit; enzyme kinetics; glassy carbon electrode; graphene; hydrolysis; hydrophilicity; nanocomposites; nanoparticles; parathion-methyl; scanning electron microscopy
Abstract:
... A sensitive amperometric acetylcholinesterase (AChE) biosensor, based on SnO2 nanoparticles (SnO2 NPs), carboxylic graphene (CGR) and nafion (NF) modified glassy carbon electrode (GCE) for the detection of methyl parathion and carbofuran has been developed. The nanocomposites of SnO2 NPs and CGR was synthesized and characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fo ...
DOI:
10.1016/j.bios.2013.04.037

92. Acetylcholinesterase biosensor based on assembly of multiwall carbon nanotubes onto liposome bioreactors for detection of organophosphates pesticides

Author:
Junxin Yan; Huanan Guan; Jia Yu; Defu Chi
Source:
Pesticide biochemistry and physiology 2013 v.105 no.3 pp. 197-202
ISSN:
0048-3575
Subject:
acetylcholinesterase; bioreactors; biosensors; carbon; carbon nanotubes; chitosan; detection limit; dichlorvos; electrochemistry; electrodes; encapsulation; enzymatic reactions; physiology; porins
Abstract:
... A novel acetylcholinesterase (AChE) biosensor based on multilayer films containing multiwall carbon nanotubes (MWCNTs), chitosan (CS) and AChE liposomes bioreactor (ALB) was developed. ALB were prepared by encapsulating the enzyme AChE in l-α-phosphatidylcholine liposomes resulting in spherical bioreactor with a mean diameter of 7.3±0.85μm. Porins were embedded into the lipid membrane, allowing fo ...
DOI:
10.1016/j.pestbp.2013.02.003

93. Acetylcholinesterase biosensor based on chitosan/prussian blue/multiwall carbon nanotubes/hollow gold nanospheres nanocomposite film by one-stepelectrodeposition

Author:
Chen Zhai; Xia Sun; Wenping Zhao; Zhili Gong; Xiangyou Wang
Source:
Biosensors & bioelectronics 2013 v.42 pp. 124-130
ISSN:
0956-5663
Subject:
acetylcholinesterase; biosensors; carbofuran; carbon; carbon nanotubes; chitosan; chlorpyrifos; detection limit; dielectric spectroscopy; electrochemistry; electrodes; electron transfer; gold; malathion; monocrotophos; nanocomposites; nanospheres; pH; scanning electron microscopy; transmission electron microscopy
Abstract:
... In this paper, chitosan–prussian blue–multiwall carbon nanotubes-hollow gold nanospheres (Chit–PB–MWNTs–HGNs) film was fabricated onto the gold electrode surface by one-step electrodeposition method; and then acetylcholinesterase (AChE) and Nafion were modified onto the film to prepare an AChE biosensor. Incorporating MWNTs and HGNs into Chit–PB hybrid film promoted electron transfer reaction, enh ...
DOI:
10.1016/j.bios.2012.10.058

94. Acetylcholinesterase biosensor based on multi-walled carbon nanotubes-SnO2-chitosan nanocomposite

Author:
Dongfei Chen; Xia Sun; Yemin Guo; Lu Qiao; Xiangyou Wang
Source:
Bioprocess and biosystems engineering 2015 v.38 no.2 pp. 315-321
ISSN:
1615-7591
Subject:
acetylcholinesterase; biosensors; cabbage; carbon; carbon nanotubes; chitosan; chlorpyrifos; detection limit; electrochemistry; electrodes; electron transfer; ferricyanides; ferrocyanides; fruits; gold; leeks; lettuce; nanocomposites; nanoparticles; pesticide residues; quantitative analysis; scanning electron microscopy
Abstract:
... A sensitive amperometric acetylcholinesterase (AChE) biosensor was developed based on the nanocomposite of multi-walled carbon nanotubes (MWCNTs), tin oxide (SnO₂) nanoparticles and chitosan (CHIT). Acetylcholinesterase (AChE) and Nafion were immobilized onto the nanocomposite film to prepare AChE biosensor for pesticide residues detection. The morphologies and electrochemistry properties of the s ...
DOI:
10.1007/s00449-014-1270-x

95. Acetylcholinesterase biosensor based on the mesoporous carbon/ferroferric oxide modified electrode for detecting organophosphorus pesticides

Author:
Qianqian Zhang; Qingcui Xu; Yemin Guo; Xia Sun; Xiangyou Wang
Source:
RSC advances 2016 v.6 no.29 pp. 24698-24703
ISSN:
2046-2069
Subject:
acetylcholinesterase; biosensors; carbon; carbon electrodes; chitosan; chlorpyrifos; dispersants; electrochemistry; electron transfer; iron oxides; methamidophos; models; pH; pesticide residues; porous media; synergism
Abstract:
... In this paper a biosensor modified by ordered mesoporous carbon–chitosan (OMC–CS)/ferroferric oxide–chitosan (Fe₃O₄–CS) was developed on the surface of screen-printed carbon electrodes (SPCEs). The acetylcholinesterase (AChE) was modified onto the film to prepare an AChE biosensor. Chitosan was used as a dispersant to disperse OMC and Fe₃O₄. The OMC and Fe₃O₄ were used to enhance the electrochemic ...
DOI:
10.1039/c5ra21799g

96. Acetylcholinesterase biosensor for carbaryl detection based on interdigitated array microelectrodes

Author:
Zhili Gong; Yemin Guo; Xia Sun; Yaoyao Cao; Xiangyou Wang
Source:
Bioprocess and biosystems engineering 2014 v.37 no.10 pp. 1929-1934
ISSN:
1615-7591
Subject:
acetylcholinesterase; biosensors; carbaryl; chitosan; detection limit; dielectric spectroscopy; electrodes; immobilized enzymes; pesticide residues
Abstract:
... In this study, an acetylcholinesterase (AChE) biosensor with superior accuracy and sensitivity was successfully developed based on interdigitated array microelectrodes (IAMs). IAMs have a series of parallel microband electrodes with alternating microbands connected together. Chitosan was used as the enzyme immobilization material, and AChE was used as the model enzyme for carbaryl detection to fab ...
DOI:
10.1007/s00449-014-1195-4

97. Acetylcholinesterase/chitosan-transition metal carbides nanocomposites-based biosensor for the organophosphate pesticides detection

Author:
Liya Zhou; Xiaoning Zhang; Li Ma; Jing Gao; Yanjun Jiang
Source:
Biochemical engineering journal 2017 v.128 pp. 243-249
ISSN:
1369-703X
Subject:
acetylcholinesterase; biosensors; carbides; chitosan; detection limit; dielectric spectroscopy; electrical conductivity; electrochemistry; malathion; nanosheets; pH; surface area
Abstract:
... A novel acetylcholinesterase (AChE) biosensor based on transition metal carbides (MXenes) nanosheets and chitosan (CS) had been fabricated successfully for detecting organophosphorous pesticides (OPs). The electrochemical behaviors of the AChE/CS-Ti3C2Tx/GCE biosensor were studied by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The parameters affecting the AChE biosens ...
DOI:
10.1016/j.bej.2017.10.008

98. Achillea millefolium essential oil and chitosan nanocapsules with enhanced activity against Tetranychus urticae

Author:
Zeinab Ahmadi; Moosa Saber; Mohammad Bagheri; Gholam Reza Mahdavinia
Source:
Journal of pest science 2018 v.91 no.2 pp. 837-848
ISSN:
1612-4758
Subject:
Achillea millefolium; Tetranychus urticae; adults; adverse effects; air; chitosan; environmental factors; essential oils; fumigants; lethal concentration 50; mortality; nanocapsules; nanoparticles; pH; pest control; pesticidal properties; pesticides; pests; toxicity
Abstract:
... Essential oils are promising candidates for the substitution of synthetic pesticides owing to their pesticidal and pest repellent features and also lower environmental side effects. Despite the pesticidal effects, the most of essential oils lose their effects against environmental conditions. Nanoformulation is a technique that may protect or improve the pesticidal efficiency of plant essential oi ...
DOI:
10.1007/s10340-017-0912-6

99. Acid pH-activated glycol chitosan/fullerene nanogels for efficient tumor therapy

Author:
Sol Kim; Dong Jin Lee; Dong Sup Kwag; Ung Yeol Lee; Yu Seok Youn; Eun Seong Lee
Source:
Carbohydrate polymers 2014 v.101 pp. 692-698
ISSN:
0144-8617
Subject:
chitosan; electrostatic interactions; fullerene; hydrophilicity; hydrophobicity; lighting; neoplasm cells; pH; singlet oxygen; therapeutics
Abstract:
... Glycol chitosan (GC) grafted with 2,3-dimethylmaleic acid (DMA) and fullerene (C₆₀) conjugates (GC-g-DMA-g-C₆₀) were developed for use in a photosensitizer prodrug. GC-g-DMA-g-C₆₀ was prepared via the simple two-step chemical grafting reactions of (i) DMA to free amine groups of GC and (ii) hydroxyl groups of GC-g-DMA to ππ carbon bonds of C₆₀. This conjugate was self-assembled to form polysacchar ...
DOI:
10.1016/j.carbpol.2013.09.108

100. Acid-Catalyzed Synthesis of Foamed Materials from Renewable Sources

Author:
Duan Ran; Ibrahem Ismail; Edlund Håkan; Norgren Magnus
Source:
Industrial & Engineering Chemistry Research 2014 v.53 no.45 pp. 17597-17603
ISSN:
1520-5045
Subject:
catalysts; cellulose; chitosan; engineering; esterification; foams; organic acids and salts; physical properties; starch
Abstract:
... In this study, lightweight biobased foamed materials were successfully synthesized by the modification of renewable polysaccharides, such as starch and microcrystalline cellulose. Low-cost and nontoxic organic acids were utilized as catalysts in the first-step esterification reaction of the synthesis. The effects of different reaction conditions on the water absorbency and weight loss of freeze-ca ...
DOI:
10.1021/ie501169w