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... 1,8-Cineole (1,8-CIN) is a monoterpene found in diverse dietary and medicinal herbs that has been reported to be effective against cardiovascular diseases.The present research was designed to elucidate the treatment effects and the underlying mechanism of 1,8-CIN on heart failure (HF).An in vitro cardiac hypertrophy model and an in vivo heart failure (HF) model induced by isoprenaline (ISO) were e ...
Artemisia; additive effect; cineole; detection limit; fractionation; gas chromatography; grapes; harvest date; high performance liquid chromatography; invasive species; mass spectrometry; menthol; odor compounds; odors; olfactometry; plants (botany); red wines; small fruits; sweet peppers; vineyards
Abstract:
... The aromatic descriptor “green”, reflecting grape unripeness in French red wines, is frequently associated with the levels of 3-alkyl-2-methoxypyrazines, particularly 3-isobutyl-2-methoxypyrazine (IBMP), which has bell pepper nuances. Nevertheless, not all green aromatic expressions in red wines correlate with 3-alkyl-2-methoxypyrazine concentrations. This study considered sensory and chemical app ...
... 1,8-cineole is a volatile growth inhibitor produced bySalvia species. We examined the effect of this allelopathic compound on the growth of other plants usingBrassica campestris as the test plant. Cineole inhibited germination and growth ofB. campestris in a dosedependent manner. WhenB. campestris was grown for 5 days with various concentrations of cineole, the length of the roots was found to be ...
... 1,8-Cineole is a plant-derived monoterpene and a major constituent of Eucalyptus essential oil. Previously, we demonstrated that 1,8-cineole inhibited hepatocellular carcinoma (HCC) HepG2 cell growth. However, the underlying mechanisms remain unknown. Here, we evaluated the mechanisms of action of 1,8-cineole and the potential benefits of its combination with anticancer compounds harboring “anti-s ...
... 1,8-Cineole (also known as eucalyptol) is mostly extracted from the essential oils of plants, which showed extensively pharmacological properties including anti-inflammatory and antioxidant mainly via the regulation on NF-κB and Nrf2, and was used for the treatment of respiratory diseases and cardiovascular, etc. Although various administration routes have been used in the application of 1.8-cineo ...
Patricia Rodrigues Lima; Tiago Sousa de Melo; Karine Maria Martins Bezerra Carvalho; Ítalo Bonfim de Oliveira; Bruno Rodrigues Arruda; Gerly Anne de Castro Brito; Vietla Satyanarayana Rao; Flávia Almeida Santos
... AIMS: Acute pancreatitis (AP) is an inflammatory condition wherein pro-inflammatory mediators, oxidative stress, and NF-κB signaling play a key role. Currently, no specific therapy exists and treatment is mainly supportive and targeted to prevent local pancreatic injury and systemic inflammatory complications. This study was aimed to examine whether 1,8-cineole, a plant monoterpene with antioxidan ...
... Essential and fixed oils have been researched as alternatives to chemical acaricides. The activity of volatile compounds from essential oils (1,8‐cineole, citral and eugenol) at 1.0% (w/v) and fixed oil (castor oil) at 0.3% (w/v) dissolved in 2.0% (v/v) dimethyl sulfoxide (DMSO) + 0.2% (w/v) Tween 80® was assessed against Rhipicephalus microplus using immersion tests. 1,8‐cineole (29.0%) and casto ...
... Guava fruit are highly perishable and deteriorate within 2 to 4 days. Moreover, these fruit are highly aromatic to the point that some consumers do not purchase it due to their overly strong aroma. We examined the potential of modified atmosphere packaging and 1-MCP treatments to improve storage life and reduce the biosynthesis of volatiles. Various quality parameters were also assessed and the ar ...
... The development of safer and more sustainable solvents is an important discipline in the context of stricter regulations and environmental protection. This work demonstrates the sustainable synthesis of a potentially bio-based, inherently nonperoxide-forming ether solvent, namely, 2,5-diethyl-2,5-dimethyloxolane (DEDMO), in quantitative yields with high atom economy (97%) and reaction mass efficie ...
... In this study, the chemical contents of essential oil acquired from Myrtus communis leaves using hydrodistillation and seed oil obtained using cold press method analyzed with gas chromatography-mass spectrometry (GC/MSD). According to the analyse result, forty-five component were identified and 1,8-cineole (21.68%), alpha-pinene (18.02%), linalool (14.12%) and alpha-terpinyl acetate (10.40%) were ...
... The variation of foliar monoterpenes in the Australian Tea Tree (Melaleuca alternifolia) has been of significant interest both to the essential oil industry as well as to ecologists. The majority of studies on leaf chemistry have been aimed directly towards obtaining oil of higher quality or quantity. In the current study, we aimed to understand how molecular mechanisms contribute to the chemical ...
Zingiber zerumbet; arithmetics; camphene; camphor; cineole; climatic factors; cluster analysis; essential oils; gas chromatography-mass spectrometry; genetic variation; genotype; germplasm; microsatellite repeats; oils; principal component analysis; rhizomes; volatile compounds; India
Abstract:
... Essential oil of twenty-five germplasms of Zingiber zerumbet from different accessions of Eastern India were analysed using Gas Chromatography-Mass Spectroscopy (GC/MS). A total of 29 constituents were identified representing between 72.45-98.93% of total area. Zerumbone content was found to be in a range of 60.1-79.59% for the tested rhizomes. Acc. Haroa (W.B) was found to contain highest amount ...
Pseudomonas aeruginosa; Staphylococcus aureus; Thymus kotschyanus; Thymus vulgaris; alpha-pinene; antibacterial properties; bacteria; buds; camphene; chemical composition; cineole; disk diffusion antimicrobial test; essential oils; flowering; gamma-terpinene; gas chromatography; mass spectrometry; myrcene; plant growth; steam distillation; temperate zones; thyme; thymol; Iran; Southern European region
Abstract:
... Thymus , an aromatic plant of the family lamiaceae, has valuable medicinal properties commonly used in traditional and modern medicine across the world. This plant is mainly native to the northern temperate regions such as southern Europe and Asia. In Iran, several species of this plant grows in most of the temperate and mountainous areas. In this study, chemical compounds of flowering shoot of tw ...
Mentha piperita nothosubsp. piperita; air; air drying; air temperature; cineole; color; equations; essential oil crops; essential oils; menthol; menthone; product quality; temperature profiles; water content
Abstract:
... Drying is the most common postharvest process to preserve medicinal and aromatic plants. Peppermint has a high worldwide commercial value. Newly harvested peppermint plants were dried by using four different drying air temperature profiles. They were constant 35°C, constant 55°C, incremental rises from 35°C to 55°C in four hours, and in eight hours. The samples were dried down to the final moistur ...
... Listerine® is one of the most popular mouthwashes worldwide and claims to combat harmful bacteria. In the past century, its recipe was changed from an essential oil mouthwash to a five‐component mixture (thymol, menthol, eucalyptol, and methyl salicylate dissolved in 27% ethanol). The aim of this study was to get preliminary information about the antimicrobial activities of individual Listerine® c ...
... A microwave-assisted hydrodistillation protocol was modified to extract essential oils from leaves of Salvia triloba L. and Laurus nobilis L. The essential oils of these plants are generally obtained by hydrodistillation or steam distillation. The volatile compounds obtained by microwave-assisted hydrodistillation and hydrodistillation methods were analyzed by GC and GC/MS. Both distillation metho ...
... An experiment was conducted at the Indian Institute of Spices Research, Regional Station, Madikeri, Karnataka, to study physiology, yield and quality responses of six small cardamoms [Elettaria car- damomum (L.) Maton] genotypes (Appangala-1, PV-1, ICRI-2, FGB-34, PV-2 and Green Gold) selected from three ecotypes (Malabar, Mysore and Vazhukka) during 2018-2019. The experiment was designed in Rando ...
... Nile tilapia were fed four levels (0, 0.25, 0.5, and 1 ml/kg) of a liquid blend of herbal essential oils (EOs) containing carvacrol, oregano, 1,8 cineol, thymol, pinene, pinene β, limonene, and propylene glycol for 60 days. The results showed higher final weight, weight gain, and specific growth rate (P<0.05) in fish delivered 0.25 and 0.5 ml EOs/kg than the control. However, the feed conversion r ...
Salvia; aerial parts; beta-caryophyllene; bioactive properties; carene; chemometrics; cineole; comprehensive two-dimensional gas chromatography; computer software; essential oils; gas chromatography-mass spectrometry; hydrodistillation; indigenous species; ionization; limonene; models; principal component analysis; sample size; spathulenol; traditional medicine; viridiflorol; volatile organic compounds; South Africa
Abstract:
... Indigenous Salvia species from southern Africa are popular traditional medicines for the treatment of a variety of conditions. They produce fragrant volatiles that can be isolated as essential oils. Some of these volatile organic compounds may play a role in the biological activities of the extracts. Three indigenous Salvia species, Salvia africana-lutea, S. lanceolata and S. chamelaeagnea, were s ...
volatile compounds; stems; cineole; essential oils; biotypes; limonene; Mentha longifolia; germacrene; chemical constituents of plants; leaves; myrcene; Lithuania
Abstract:
... The volatile constituents of Mentha longifolia L. were isolated by hydrodistillation and simultaneous distillation-extraction method in the Likens-Nickerson apparatus and analyzed by GC and GC/MS. Seventy compounds were identified, 62 positively and 8 tentatively. The major constituents were piperitenone oxide (44.2% and 57.2%), 1,8-cineole (15.14% and 8.44%), myrcene (10.02% and 6.27%), limonene ...
acetates; acetoin; alpha-terpineol; analysis of variance; camphene; cineole; comparative study; diacetyl; gas chromatography-mass spectrometry; headspace analysis; hydroxymethylfurfural; octenol; p-cresol; protected designation of origin; volatile compounds; wine vinegars; wines
Abstract:
... The characteristic volatile profile of the Spanish Vinagre de Jerez (VJ), Vinagre de Condado de Huelva (VC) and Vinagre de Montilla-Moriles (VMM) protected designation of origin (PDO) wine vinegars has been studied and compared for the first time by headspace stir bar sorptive extraction-gas chromatography–mass spectrometry (HSSE-GC–MS). The possible markers of each category and PDO were assessed. ...
... Eucalyptus gunnii is a fast-growing, cold-tolerant tree species endemic to Tasmania that is suitable for growing as short-rotation coppice (SRC) plantations in the UK. Fast growing eucalypts such as E. gunnii could potentially deliver higher biomass yields with a superior calorific value for the domestic bioenergy market than other SRC plantation species such as willow or poplar. However, eucalypt ...
gamma-terpinene; cineole; essential oils; alpha-pinene; biotypes; chemical constituents of plants; Scrophulariaceae; Vietnam
Abstract:
... The essential oil from the aerial parts of Adenosma glutinosum (L.) Druce var. caeruleum Tsoong (Scrophulariaceae) was analyzed by a combination of high resolution GC and GC/MS. More than 35 constituents have been identified, of which the major ones were alpha-pinene (22.7%), 1,8-cineole (18.2%) and gamma-terpinene (16.9%). ...
myricetin; polyphenols; nuclear magnetic resonance spectroscopy; Myrtus; quantitative analysis; free radicals; cineole; 2,2-diphenyl-1-picrylhydrazyl; herbal tea; glucosides; black tea; antioxidant activity; phytopharmaceuticals; chemical structure; leaves
Abstract:
... The phytochemical profile of decoction and infusion, obtained from the dried leaves of M. nivellei, consumed as tea in Saharan region, was characterized by UHPLC-PDA-HRMS. Fourteen compounds were characterized and, to confirm the proposed structures a preparative procedure followed by NMR spectroscopy was applied. Compound 3 (2-hydroxy-1,8-cineole disaccharide) was a never reported whereas a bicyc ...
enantiomers; Eucalyptus; cineole; essential oils; beta-phellandrene; chemical constituents of plants; Queensland
Abstract:
... Hydrodistillation of leaves of a new species of eucalypt, Eucalyptus dura, produced an oil rich in beta-phellandrene (16.4%) and 1,8-cineole (22.6%). Chirality of the oil was unusual as most chiral compounds were represented by only one enantiomer. The monoterpenes alpha-pinene and limonene had both enantiomers present. The high beta-phellandrene and 1,8-cineole content of the oil makes it suitabl ...
... In the extraction process of essential oils (EOs), one of the major problems of traditional methods is long extraction times. Ohmic-assisted hydrodistillation (OAHD) is a specific hydrodistillation (HD) technique utilizing ohmic heating to generate heat faster and in a different form from traditional methods. OAHD was applied as a novel technology for the isolation of EO from the aerial parts of M ...
... The objective of this experimental investigation was to develop a novel two‐step process for production of high‐quality chicken powder infused with basil. The first step consists of ultrasonication of an aqueous chicken pieces mixed with chopped basil leaves to enhance extraction of basil flavour and also pretreat the chicken microstructure to intensify the drying kinetics in the second step. The ...
cineole; essential oils; geographical variation; limonene; chemical constituents of plants; Hyssopus officinalis; France; Italy
Abstract:
... The essential oils of Hyssopus officinalis L. var. decumbens (HOI) from France (Banon) and H. officinalis (HO) from Italy (Piedmont) were studied by GC and GC/MS. The bicyclic monoterpene ketones, pinocamphone and isopinocamphone, were present in HO (4.4% and 43.4%, respectively, in accordance with the ISO 9841 Standard, 1991 E), but their percentages were very low in HOD, where instead linalool ( ...
Alpinia; Bacillus subtilis; Escherichia coli; Pseudomonas aeruginosa; Staphylococcus aureus; alpha-phellandrene; antibacterial properties; bacteria; beta-pinene; chemical composition; cineole; electrical conductivity; electrolytes; erythrocytes; essential oils; food biopreservatives; food industry; gas chromatography-mass spectrometry; hemolysis; humans; leaves; membrane permeability; minimum inhibitory concentration; ornamental plants; protein synthesis; scanning electron microscopes; scanning electron microscopy; spices; streptomycin; traditional medicine; China
Abstract:
... Essential oils (EOs) have attracted great interest for their potential as safer biopreservatives. Alpinia guinanensis is widely used as an ornamental plant, food spice and folk medicine in China. This study aimed to explore the leaves EO of A. guinanensis as a potential biopreservative. The chemical composition, antibacterial activity, mechanism and hemolysis of the leaves EO were studied for the ...
Salvia multicaulis; antioxidant activity; antioxidants; breast neoplasms; cell lines; cineole; colorectal neoplasms; cytotoxicity; dietary supplements; diterpenoids; enzymes; essential oils; ethanol; fibroblasts; flowers; food preservatives; gas chromatography-mass spectrometry; leaves; limonene; liquid chromatography; neoplasm cells; odors; ovarian neoplasms; pharmaceutical industry; root extracts; rosmarinic acid; traditional medicine
Abstract:
... The importance of Salvia L. species, being used as traditional medicine, in the scientific world is increasing day by day. The relationship between health and traditional-modern life, promotes the creation of new value added food products. Within this context, in this study, it was aimed to biologically and chemically investigate the essential oil and ethanol extracts of the Salvia multicaulis Vah ...
Croton; antimalarials; antioxidants; chemistry; cineole; diabetes; ethnobotany; fever; flavonoids; fungi; inflammation; malaria; pharmacology; quality control; sesquiterpenoids; traditional medicine; Southern Africa
Abstract:
... The genus Croton (Euphorbiaceae) encompasses 1300 species, which consist of a variety of trees and shrubs distributed across the world. About 26 species are harboured on the African continent. This genus plays an essential role in African folk medicine. Croton species are traditionally used for the treatment of many diverse conditions such as diabetes, malaria, sexually transmitted diseases, cance ...
... With population growth and the increasing human demand for crops, chemical insecticides have been used to reduce pests. Due to the adverse effects of these chemicals on the environment and health, several studies have investigated alternatives such as natural insecticides derived from essential oils or plant extracts. This review article was provided by using search engines such as Google scholar, ...
... In traditional medicine, Ocimum gratissimum (clove basil) is used in the treatment of various diseases such as diabetes, cancer, inflammation, anaemia, diarrhoea, pains, and fungal and bacterial infections. The present study reviewed the phytochemicals, essential oils, and pharmacological activities of O. gratissimum. The bioactive compounds extracted from O. gratissimum include phytochemicals (ol ...
Elettaria cardamomum; acetates; cardamom; chemical composition; cineole; essential oils; gas chromatography-mass spectrometry; hydrodistillation; seeds; sensory properties; ultrasonics; volatile compounds
Abstract:
... The influence of ultrasonic assisted extraction (UAE) followed by hydrodistillation of Elettaria cardamomum L. seeds was investigated. The yield, volatile components and sensory characteristics of the extracted essential oils (EO) were evaluated. Power of ultrasonic and time of sonication were optimized. The chemical composition of the EO was identified by gas chromatography–mass spectrometry (GC– ...
harvest date; interspecific variation; Rosmarinus officinalis; geographical variation; essential oils; alpha-pinene; cineole; camphor; chemical constituents of plants; yields; chemotaxonomy; Morocco
Abstract:
... The chemotaxonomy of Moroccan rosemary was studied. The essential oil, which was obtained by hydrodistillation of Rosmarinus officinalis L. from different regions of Morocco (Rabat, Taforalt and Elateuf) was analyzed by GC and GC/MS. The variations in chemical composition are important between plant populations. We have defined three chemotypes of R. officinalis: the alpha-pinene-chemotype (alpha- ...
... This study aims at performing a chemical analysis of the essential oils of Laurus nobilis (LNEO), Lavandula stoechas (LSEO) and Mentha pulegium (MPEO) by GC-MS. The possible synergistic effects of their combinations on anticholinesterase and antioxidant activities were investigated. LNEO was dominated by 1,8-Cineole. Pulegone was found to be the major constituent of MPEO, while fenchone was the ma ...
Helena Taina Diniz-Silva; Janaína Batista de Sousa; Jessica da Silva Guedes; Rita de Cássia Ramos do Egypto Queiroga; Marta Suely Madruga; Josean Fechine Tavares; Evandro Leite de Souza; Marciane Magnani
... The effects of Origanum vulgare L. (OVEO) and Rosmarinus officinalis L. (ROEO) essential oils in combination on the counts of a mesophilic starter co-culture and Escherichia coli O157:H7 in cheese were determined during 21 days of refrigerated storage. Prevalent OVEO and ROEO terpenes, as well as the physicochemical and sensory aspects of cheese, were also determined. OVEO (0.03 μL/g) and ROEO (1. ...
... The interest in the use of Eucalyptus genus members, in parallel with preclinical studies has been steadily growing over the last few decades in the field of pharmaceuticals, agriculture, cosmetics, food, etc. Eucalyptol (1,8-cineole or cineole), the main terpenoid constituent in Eucalyptus species, has been studied in both preclinical and clinical settings for its various pharmacologic activities ...
... The odor problems in plain reservoirs are more complex compared to valley reservoirs and ground water reservoirs. Just as YL Reservoir with wetlands ecosystem in Lixiahe Plain, Jiangsu Province has been suffering from complex odors, however, the odorants were unclear. In this study, a systematic study on odorants characterization and evaluation of plain YL reservoir was accomplished. Totally musty ...
... The present study aimed at the determination of volatile compounds (VOCs) of Greek Quercus ilex honey, which comprises a rarely studied honeydew honey, from different regions and to characterize its provenance using a targeted chemometric evaluation of the semi-quantitative data of VOCs determined with headspace solid phase microextraction coupled to gas chromatography/mass spectrometry (HS-SPME/G ...
Salvia desoleana; acetates; amplified fragment length polymorphism; camphor; cineole; diterpenoids; essential oils; gas chromatography-mass spectrometry; genetic variation; germacrene; indigenous species; industry; leaves; perennials; risk; terpinolene; variance; Italy; Sardinia
Abstract:
... Salvia desoleana Atzei et Picci is a herbaceous perennial plant endemic to Sardinia, Italy. Its leaves are a source of essential oil, used in the pharmaceutical and cosmetic industries. Due to the increasing interest in the essential oils production, cultivated accessions have supplanted many wild populations which had become small, fragmented and isolated with a serious risk of genetic erosion. W ...
... Acaricidal effects of three essential oils extracted from Mexican oregano leaves (Lippia graveolens Kunth), rosemary leaves (Rosmarinus officinalis L.), and garlic bulbs (Allium sativum L.) on 10-d-old Rhipicephalus (Boophilus) microplus (Canestrini) tick larvae were evaluated by using the larval packet test bioassay. Serial dilutions of the three essential oils were tested from a starting concent ...
... This study aimed to determine the chemical composition and evaluate the acaricidal activity of essential oils (EOs) from Curcuma zedoaria and Alpinia zerumbet rhizomes against Rhipicephalus microplus in vitro. EOs were obtained by hydrodistillation and chemical characterization was performed by gas chromatography coupled with mass spectrometry (GC-MS). The acaricidal activity of each EO was firstl ...
Ocimum gratissimum; ticks; Rhipicephalus microplus; gamma-terpinene; thymol; cineole; chemical analysis; essential oils; bioassays; oils; acaricides; lethal concentration 50; acaricidal properties; larvae; mass spectrometry; gas chromatography; eugenol; New Caledonia; Cameroon
Abstract:
... The aim of this study was to evaluate the acaricidal activity on the cattle tick Rhipicephalus (Boophilus) microplus of essential oils from three Ocimum species. Acaricidal activity of five essential oils extracted from Ocimum gratissimum L. (three samples), O. urticaefolium Roth, and O. canum Sims was evaluated on 14- to 21-day-old Rhipicephalus microplus tick larvae using larval packet test bioa ...
... Some essential oils obtained from the branches of four Pinus species (P. pinea L., P. halepensis Mill., P. pinaster Soil in Ait., and P. nigra Arnold) have been evaluated for their acaricidal activity by aerial diffusion against the stored food mite Tyrophagus putrescentiae (L.). All the essential oils showed a good efficacy, but P. pinea oil and its two constituents 1,8-cineole and limonene were ...
... The objective of this experiment was to evaluate the acaricidal activity of Senecio cannabifolius essential oil, and two of its constituents, eucalyptol and camphor. Efficacy against females and larvae of Rhipicephalus (Boophilus) microplus was assessed by the adult immersion test (AIT) and the larval immersion test (LIT). The oil was analyzed by gas chromatography-flame ionization detection (GC-F ...
... Six natural monoterpenes (1,8-cineole, (-)-citronellal, limonene, α-pinene, pulegone and 4-terpineol) showed high acaricidal activity by fumigant and contact actions against adult females of the two-spotted spider mite, Tetranychus urticae Koch. The monoterpenes exhibited varying degrees of acaricidal potency using contact toxicity test after 24 and 48 h of treatment, where the LC50 values were <1 ...
... This work has demonstrated the ixodicidal and insect antifeedant effects of essential oils from 14 experimentally cultivated aromatic plants. The strong ixodicidal and antifeedant oils corresponded to Thymus zygis, Thymus vulgaris, Satureja montana, Oreganum virens, and Mentha suaveolens. The moderately active oils were from Lavandula angustifolia, Mentha piperita, Mentha spicata, Artemisa herba-a ...
... Essential oils from six plant species that occur in the north part of Alexandria governorate, Egypt, were extracted by hydrodistillation in a Clevenger-type device. The chemical compositions of the essential oils were analysed using gas chromatography-mass spectrometry. The essential oils were tested for their toxicities towards the adults of Tetranychus urticae by contact and fumigant methods. Th ...