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... 1,8-Cineole (1,8-CIN) is a monoterpene found in diverse dietary and medicinal herbs that has been reported to be effective against cardiovascular diseases.The present research was designed to elucidate the treatment effects and the underlying mechanism of 1,8-CIN on heart failure (HF).An in vitro cardiac hypertrophy model and an in vivo heart failure (HF) model induced by isoprenaline (ISO) were e ...
... Volatile monoterpenes such as 1,8-cineole inhibit the growth of Brassica campestris seedlings in a dose-dependent manner, and the growth-inhibitory effects are more severe for roots than hypocotyls. The preferential inhibition of root growth may be explained if the compounds inhibit cell proliferation more severely than cell elongation because root growth requires both elongation and proliferation ...
Artemisia; additive effect; cineole; detection limit; fractionation; gas chromatography; grapes; harvest date; high performance liquid chromatography; invasive species; mass spectrometry; menthol; odor compounds; odors; olfactometry; plants (botany); red wines; small fruits; sweet peppers; vineyards
Abstract:
... The aromatic descriptor “green”, reflecting grape unripeness in French red wines, is frequently associated with the levels of 3-alkyl-2-methoxypyrazines, particularly 3-isobutyl-2-methoxypyrazine (IBMP), which has bell pepper nuances. Nevertheless, not all green aromatic expressions in red wines correlate with 3-alkyl-2-methoxypyrazine concentrations. This study considered sensory and chemical app ...
... 1,8-cineole is a volatile growth inhibitor produced bySalvia species. We examined the effect of this allelopathic compound on the growth of other plants usingBrassica campestris as the test plant. Cineole inhibited germination and growth ofB. campestris in a dosedependent manner. WhenB. campestris was grown for 5 days with various concentrations of cineole, the length of the roots was found to be ...
... 1,8-Cineole is a plant-derived monoterpene and a major constituent of Eucalyptus essential oil. Previously, we demonstrated that 1,8-cineole inhibited hepatocellular carcinoma (HCC) HepG2 cell growth. However, the underlying mechanisms remain unknown. Here, we evaluated the mechanisms of action of 1,8-cineole and the potential benefits of its combination with anticancer compounds harboring “anti-s ...
... 1,8-Cineole (also known as eucalyptol) is mostly extracted from the essential oils of plants, which showed extensively pharmacological properties including anti-inflammatory and antioxidant mainly via the regulation on NF-κB and Nrf2, and was used for the treatment of respiratory diseases and cardiovascular, etc. Although various administration routes have been used in the application of 1.8-cineo ...
Patricia Rodrigues Lima; Tiago Sousa de Melo; Karine Maria Martins Bezerra Carvalho; Ítalo Bonfim de Oliveira; Bruno Rodrigues Arruda; Gerly Anne de Castro Brito; Vietla Satyanarayana Rao; Flávia Almeida Santos
... AIMS: Acute pancreatitis (AP) is an inflammatory condition wherein pro-inflammatory mediators, oxidative stress, and NF-κB signaling play a key role. Currently, no specific therapy exists and treatment is mainly supportive and targeted to prevent local pancreatic injury and systemic inflammatory complications. This study was aimed to examine whether 1,8-cineole, a plant monoterpene with antioxidan ...
... Transportation stress is considered the major cause of production and economic losses in aquaculture. Here, we examined the effects of dried ginger extract (GE) and 1,8-cineole (CIN) on juvenile largemouth bass (Micropterus salmoides) subjected to simulated transport by quantifying serum metabolites, antioxidant enzyme activity, and haematological features in conjunction with whole transcriptome a ...
... Essential and fixed oils have been researched as alternatives to chemical acaricides. The activity of volatile compounds from essential oils (1,8‐cineole, citral and eugenol) at 1.0% (w/v) and fixed oil (castor oil) at 0.3% (w/v) dissolved in 2.0% (v/v) dimethyl sulfoxide (DMSO) + 0.2% (w/v) Tween 80® was assessed against Rhipicephalus microplus using immersion tests. 1,8‐cineole (29.0%) and casto ...
... Guava fruit are highly perishable and deteriorate within 2 to 4 days. Moreover, these fruit are highly aromatic to the point that some consumers do not purchase it due to their overly strong aroma. We examined the potential of modified atmosphere packaging and 1-MCP treatments to improve storage life and reduce the biosynthesis of volatiles. Various quality parameters were also assessed and the ar ...
... The development of safer and more sustainable solvents is an important discipline in the context of stricter regulations and environmental protection. This work demonstrates the sustainable synthesis of a potentially bio-based, inherently nonperoxide-forming ether solvent, namely, 2,5-diethyl-2,5-dimethyloxolane (DEDMO), in quantitative yields with high atom economy (97%) and reaction mass efficie ...
... In this study, the chemical contents of essential oil acquired from Myrtus communis leaves using hydrodistillation and seed oil obtained using cold press method analyzed with gas chromatography-mass spectrometry (GC/MSD). According to the analyse result, forty-five component were identified and 1,8-cineole (21.68%), alpha-pinene (18.02%), linalool (14.12%) and alpha-terpinyl acetate (10.40%) were ...
Salvia desoleana; acetates; amplified fragment length polymorphism; camphor; cineole; diterpenoids; essential oils; gas chromatography-mass spectrometry; genetic variation; germacrene; indigenous species; industry; leaves; perennials; risk; terpinolene; variance; Italy; Sardinia
Abstract:
... Salvia desoleana Atzei et Picci is a herbaceous perennial plant endemic to Sardinia, Italy. Its leaves are a source of essential oil, used in the pharmaceutical and cosmetic industries. Due to the increasing interest in the essential oils production, cultivated accessions have supplanted many wild populations which had become small, fragmented and isolated with a serious risk of genetic erosion. W ...
... Acaricidal effects of three essential oils extracted from Mexican oregano leaves (Lippia graveolens Kunth), rosemary leaves (Rosmarinus officinalis L.), and garlic bulbs (Allium sativum L.) on 10-d-old Rhipicephalus (Boophilus) microplus (Canestrini) tick larvae were evaluated by using the larval packet test bioassay. Serial dilutions of the three essential oils were tested from a starting concent ...
... This study aimed to determine the chemical composition and evaluate the acaricidal activity of essential oils (EOs) from Curcuma zedoaria and Alpinia zerumbet rhizomes against Rhipicephalus microplus in vitro. EOs were obtained by hydrodistillation and chemical characterization was performed by gas chromatography coupled with mass spectrometry (GC-MS). The acaricidal activity of each EO was firstl ...
Ocimum gratissimum; ticks; Rhipicephalus microplus; gamma-terpinene; thymol; cineole; chemical analysis; essential oils; bioassays; oils; acaricides; lethal concentration 50; acaricidal properties; larvae; mass spectrometry; gas chromatography; eugenol; New Caledonia; Cameroon
Abstract:
... The aim of this study was to evaluate the acaricidal activity on the cattle tick Rhipicephalus (Boophilus) microplus of essential oils from three Ocimum species. Acaricidal activity of five essential oils extracted from Ocimum gratissimum L. (three samples), O. urticaefolium Roth, and O. canum Sims was evaluated on 14- to 21-day-old Rhipicephalus microplus tick larvae using larval packet test bioa ...
... Some essential oils obtained from the branches of four Pinus species (P. pinea L., P. halepensis Mill., P. pinaster Soil in Ait., and P. nigra Arnold) have been evaluated for their acaricidal activity by aerial diffusion against the stored food mite Tyrophagus putrescentiae (L.). All the essential oils showed a good efficacy, but P. pinea oil and its two constituents 1,8-cineole and limonene were ...
... BACKGROUND: Treatment of Psoroptes ovis in cattle is limited to topical acaricides or systemic treatment with macrocyclic lactones. Treatment failure of macrocyclic lactones has been reported. The aim of this study was to evaluate a potential alternative treatment against P. ovis. METHODS: The acaricidal activity against P. ovis of four plant-derived essential oil components, i.e. geraniol, eugeno ...
... The objective of this experiment was to evaluate the acaricidal activity of Senecio cannabifolius essential oil, and two of its constituents, eucalyptol and camphor. Efficacy against females and larvae of Rhipicephalus (Boophilus) microplus was assessed by the adult immersion test (AIT) and the larval immersion test (LIT). The oil was analyzed by gas chromatography-flame ionization detection (GC-F ...
... Six natural monoterpenes (1,8-cineole, (-)-citronellal, limonene, α-pinene, pulegone and 4-terpineol) showed high acaricidal activity by fumigant and contact actions against adult females of the two-spotted spider mite, Tetranychus urticae Koch. The monoterpenes exhibited varying degrees of acaricidal potency using contact toxicity test after 24 and 48 h of treatment, where the LC50 values were <1 ...
... This work has demonstrated the ixodicidal and insect antifeedant effects of essential oils from 14 experimentally cultivated aromatic plants. The strong ixodicidal and antifeedant oils corresponded to Thymus zygis, Thymus vulgaris, Satureja montana, Oreganum virens, and Mentha suaveolens. The moderately active oils were from Lavandula angustifolia, Mentha piperita, Mentha spicata, Artemisa herba-a ...
... Essential oils from six plant species that occur in the north part of Alexandria governorate, Egypt, were extracted by hydrodistillation in a Clevenger-type device. The chemical compositions of the essential oils were analysed using gas chromatography-mass spectrometry. The essential oils were tested for their toxicities towards the adults of Tetranychus urticae by contact and fumigant methods. Th ...
... Varroa destructor is an external parasitic mite that is a serious pest of honeybees and has caused severe losses of colonies worldwide. One of the feasible alternative treatments being used for their control is essential oils. The aim of this work was to evaluate the bioactivity of some essential oils on V. destructor and Apis mellifera in relation with their chemical composition and physicochemic ...
Callistemon; Eucalyptus dives; Eucalyptus ovata; Kunzea; Melaleuca; Tetranychus urticae; adults; alpha-pinene; beans; bioassays; cineole; dipping; egg production; eggs; essential oils; females; gas chromatography; leaves; mass spectrometry; mites; mortality; testing; Australia
Abstract:
... Nineteen plant essential oils (EOs) extracted from the family Myrtaceae growing in Australia were screened for their acaricidal and repellent activities against two-spotted spider mite, Tetranychus urticae Koch (Acari: Tetranychidae), in the laboratory by dipping method and choice- and no-choice tests. Acaricidal bioassays showed that five EOs of Callistemon viminalis, Eucalyptus bicostata, Eucaly ...
... The objective of this study was to evaluate the acaricidal activity of the volatile oils of three species of Croton, Euphorbiaceae, against the cattle tick Rhipicephalus microplus. The volatile oils were obtained by hydrodistillation, analyzed by GC–MS and GC-FID and their acaricidal activity was evaluated by the larval packet test and adult immersion test. The volatile oils from Croton conduplica ...
... The essential oil from the leaves of Lippia gracilis was investigated for fumigant and residual activity against Tetranychus urticae (Acari: Tetranychidae) and Neoseiulus californicus (Acari: Phytoseiidae). The results were compared to eugenol, Ortus® and Azamax®, as positive controls. Gas chromatography (GC) and GC/mass spectrometry analysis enabled the identification of 28 compounds, accounting ...
... BACKGROUND: The acaricidal activity of Salvia lavandulifolia oil and its major components was evaluated using contact and vapor bioassays. Synergistic interactions among components contained in S. lavandulifolia oil were studied. RESULTS: The 50% lethal dose (LD₅₀) of S. lavandulifolia oil was 3.66, 3.37, and 5.04 μg cm⁻³, respectively, in the vapor bioassay against Dermatophagoides farinae, Derma ...
... In this study, accelerated solid phase dynamic extraction (ASPDE) technique was used to identify biogenic volatile organic compounds (BVOCs) emitted from Norway spruce (Picea abies). Compounds that were determined in tree samples are: tricycylene, α-pinene, camphene, β-pinene, myrcene, 3-carene, p-cymene, limonene, cineole, α-phellandrene, α-terpinene, γ-terpinene and terpinolene. ASPDE showed a p ...
... 1. The aim was to evaluate the acaricidal effects of pure active components of essential oils against poultry red mite (Dermanyssus gallinae) as an alternative to chemical acaricides (organophosphates and pyrethroids). 2. The toxicities of five pure active components of essential oils (eugenol from clove bud, eucalyptol from rosemary, limonene from citrus fruits, linalool from lavender and cinnama ...
... We have tested acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of nineteen essential oils obtained from cultivated plants, namely one from Anethum graveolens L. (organic fertilizer), two from Foeniculum vulgare Mill. collected at fullymature and flowering stages (organic fertilizer), two from Melissa officinalis L. (cultivated using organic and chemical fertilize ...
... In the search for new leishmanicidal agents, Thymus capitellatus Hoffmanns. & Link (family Lamiaceae) volatile extract and its major compounds, 1,8-cineole and borneol, were tested against Leishmania infantum, Leishmania tropica and Leishmania major. Plant volatile extract (essential oil) was analysed by GC and GC–MS and the activity of essential oil on Leishmania promastigotes viability was asses ...
Wesley Lyeverton Correia Ribeiro; Iara Tersia Freitas Macedo; Jessica Maria Leite dos Santos; Erick Falcão de Oliveira; Ana Lourdes Fernandes Camurça-Vasconcelos; Haroldo Cesar Beserra de Paula; Claudia Maria Leal Bevilaqua
... Phytotherapy has been described as an alternative method for the control of gastrointestinal nematodes in small ruminants. Goal of the encapsulation of essential oils in biopolymer matrices is to optimize the biological effects of these oils. The aim of the present study was to evaluate the in vitro and in vivo anthelmintic activity of encapsulated Eucalyptus staigeriana essential oil (EncEs) on t ...
dose response; chemical constituents of plants; Botrytis cinerea; cineole; essential oils; camphor; benomyl; Salvia officinalis; iprodione; antifungal properties
Abstract:
... The action of Salvia officinalis L. essential oil, of its hydrocarbon and oxygenated fractions, and of its main components, alpha- and beta-thujone, 1,8-cineole and camphor, were tested or a strain of Botrytis cinerea Pers. a chrysanthemum pathogen (Chrysanthemum morifolium Ramat and compared with the action of two synthetic plant fungicides, iprodione and benomyl, on the same fungus. The essentia ...
... Hyptis suaveolens (Lamiaceae), a plant traditionally used as a mosquito repellent, has been investigated for repellent properties against nymphs of the tick Ixodes ricinus. Essential oils and volatile compounds of fresh and dried leaves, from plants originating from Laos and Guinea-Bissau, were identified by GC–MS and tested in a tick repellency bioassay. All the essential oils were strongly repel ...
... Thymol and 1,8-cineole are now known bioinsecticidal monoterpenes occurring in many essential oils. The present study determined their toxicity on insectivorous guppy fish, Poecilia reticulata Peters, 1859 known to feed on mosquito larvae. The toxicity was recorded post 24 h treatment in experimental aquaria. The estimated median lethal concentration (LC50) values of thymol and 1,8-cineole for fem ...
... The stable fly, Stomoxys calcitrans (Linnaeus 1758), is a hematophagous fly responsible for causing loss of performance in horses, causing losses in cattle productivity, and impacting the animals' health through the spread of pathogenic microorganisms. The objective of this work was to investigate the insecticidal activity of essential oil obtained from Melaleuca alternifolia (Cheel), presenting h ...
... Chemical irritants useful as repellents for brown treesnakes (Boiga irregularis) were identified. Exposure to various compounds produced a range of intensities for locomotory behavior in snakes. Essential oils comprised of 10 g liter−1 solutions of cedarwood, cinnamon, sage, juniper berry, lavender and rosemary each were potent snake irritants. Brown treesnakes exposed to a 2-s burst of aerosol of ...
... BACKGROUND: Today, few known plant species provide both an essential oil (EO) and a vegetable oil (VO). Seed and husk of two Aframomum species were investigated and compared in terms of EO, fatty acids, tocopherols, and tocotrienols. RESULTS: EO yield reaches 15.3 g kg⁻¹ in the seeds and 3.2 g kg⁻¹ in the husks, while VO yield is 180.0 g kg⁻¹ in the seeds and 25.0 g kg⁻¹ in the husks. β‐Pinene, 1, ...
... The effect of various amounts of nitrogen fertilizer (0, 50, 100, 150, 200 and 250 kg ha⁻¹) on yield and quality traits of Anatolian sage (Salvia fruticosa Mill.) were investigated under Turkey’s Eskişehir ecological conditions in 2016–2018. Except essential oil content, all parameters examined in this study increased significantly with nitrogen applications. While dry leaf yield increased signifi ...
Salvia officinalis; cineole; drugs; essential oils; fens; leaves; sage
Abstract:
... This research was carried out to determine the agricultural and technological properties of 10 B-clones selected from 60 A-clones derived from the clone selection together with standard variety (Extracta) in common sage (Salvia officinalis L.). The experiment was laid out in a randomized complete block design with three replications. In each B clone, fresh herb yield (kg/da), drug herb yield (kg/d ...
... Lavender is native of the Mediterranean region and is widely cultivated in southern Europe, beginning in the southeastern Alps of France. The presence of oxygenated monoterpenes gives the essential oil medicinal properties and therapeutic benefits. The content and composition of essential oil of herbs depend on different factors, such as climate, geographical origin, harvest season and fertilizers ...
... In nature, plants are constantly challenged by an array of drought episodes, which critically affect the distribution of the plants. The drought episodes might occur recurrently, so the plants endure drought by adjusting and shifting their metabolisms. The impacts of subjecting plants to drought stress have been widely investigated, but reports on how reiterated drought stress affects the plants a ...
Corymbia citriodora; Human immunodeficiency virus; alpha-terpineol; bioactive properties; breathing; chemometrics; cineole; citronellol; disease control; drug resistance; essential oils; fractionation; gas chromatography-mass spectrometry; linalool; metabolomics; patients; public health; spathulenol; therapeutics; tuberculosis
Abstract:
... The rapid emergence of multi- and extensively drug-resistant tuberculosis (MDR/XDR-TB) has created a pressing public health problem, which mostly affects regions with HIV/AIDS prevalence and represents a new constraint in the already challenging disease management of tuberculosis (TB). The present work responds to the need to reduce the number of contagious MDR/XRD-TB patients, protect their immed ...
... Volatile organic compounds (VOCs) are produced by plants, fungi, bacteria and animals. These compounds are metabolites originated mainly in catabolic reactions and can be involved in biological processes. In this study, the airborne effects of five monoterpenes (α-pinene, limonene, eucalyptol, linalool, and menthol) on the growth and oxidative status of the rhizobial strain Rhizobium leguminosarum ...
Artemisia tridentata; alpha-pinene; beta-caryophyllene; borneol; cineole; gas chromatography-mass spectrometry; herbivores
Abstract:
... When plants receive volatiles from a damaged plant, the receivers become more resistant to herbivory. This phenomenon has been reported in many plant species and called plant-plant communication. Lab experiments have suggested that several compounds may be functioning as airborne signals. The objective of this study is to identify potential airborne signals used in communication between sagebrush ...
... Citrus tolerance to huanglongbing could result from tolerance to the pathogen Candidatus Liberibacter asiaticus (CLas) and/or to its vector Diaphorina citri. Field observations and greenhouse-controlled studies showed that some citrus cultivars were more tolerant than others. However, the mechanism(s) behind the tolerance has not been determined yet. Using GC-MS, we investigated the volatile organ ...
... The chemical profile and allelopathic effect of the volatile organic compounds (VOCs) produced by a dominant shrub Serphidium kaschgaricum (Krasch.) Poljak. growing in northwestern China was investigated for the first time. Serphidium kaschgaricu was found to release volatile compounds into the surroundings to affect other plants’ growth, with its VOCs suppressing root elongation of Amaranthus ret ...
... Research on the causes of grassland degradation in the Inner Mongolia has mostly focused on anthropogenic activities. Few studies examined plant interactions during the processes of grassland degradation. In this study, we found that the major constituents of the VOCs from undamaged Artemisia frigida were eucalyptol, camphene, (E)-3-hexen-1-ol acetate, α-terpineol, β-terpineol, (R)-(â)-p-menth ...
... Grassland of Inner Mongolia, the main grassland region of China and part of the Eurasia Steppe that stretches from East China to Hungary, is among the most seriously degraded grasslands in China. Previous studies on causes of grassland degradation in this region focused primarily on anthropogenic activities, such as rapid development, ranching, agricultural activities, and mining for mineral resou ...