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- Iliya Shulman; Sergei Ogurcov; Alexander Kostennikov; Alexander Rogozin; Ekaterina Garanina; Galina Masgutova; Mikhail Sergeev; Albert Rizvanov; Yana Mukhamedshina
- Biology 2021 v.10 no.2 pp. -
- animal injuries; blood serum; cerebrospinal fluid; cytokines; feasibility studies; fibrin; models; spinal cord; swine; therapeutics
- ... Peripheral blood presents an available source of cells for both fundamental research and clinical use. In our study, we have evaluated the therapeutic potential of peripheral blood mononuclear cells (PBMCs) excluding the preliminary sorting or mobilization of peripheral blood stem cells. We have evaluated the regenerative potential of PBMCs embedded into a fibrin matrix (FM) in a model of pig spin ...
- Zhaoxiang Liu; Hua Zhang; Hong Xia; Baocheng Wang; Renwen Zhang; Qun Zeng; Lingzhi Guo; Kui Shen; BaTa Wang; Yanheng Zhong; Zhizhong Li; Guodong Sun
- Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
- CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
- ... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...