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- Francesco Finamore; Jean-Luc Reny; Sarah Malacarne; Pierre Fontana; Jean-Charles Sanchez
- Journal of proteomics 2019 v.192 pp. 258-266
- acetylation; aspirin; blood platelets; cardiovascular diseases; diabetes; glucose; glycation; hyperglycemia; mass spectrometry; patients; prostaglandin synthase; proteins; risk factors; serine
- ... Diabetes is a major risk factor for cardiovascular diseases. Although aspirin is considered a cornerstone of the prevention and treatment of atherothrombotic-related ischemic events, this antiplatelet drug appears to be less effective in patients with poorly controlled diabetes. It has been suggested that the glycation of platelet proteins plays a pivotal role in poor responsiveness to aspirin. Ho ...
- Arraa M. Saghir Afifeh; Monica Verdoia; Matteo Nardin; Federica Negro; Filippo Viglione; Roberta Rolla; Giuseppe De Luca; Novara Atherosclerosis Study Group (NAS)
- Nutrition, metabolism, and cardiovascular diseases 2021 v.31 no.1 pp. 36-43
- C-reactive protein; age; angiography; biomarkers; blood platelets; calcitriol; cardiovascular diseases; chemiluminescence immunoassays; cholecalciferol; correlation; creatinine; diabetes; diuretics; exhibitions; fibrinogen; homocysteine; infection; metabolism; pandemic; patients; prediction; renal failure; risk; uric acid; variability; vitamin D deficiency
- ... Vitamin D deficiency is a pandemic disorder affecting over 1 billion of subjects worldwide. Calcitriol (1,25(OH)2D) represents the perpetrator of the several systemic effects of vitamin D, including the anti-inflammatory, antithrombotic and anti-atherosclerotic actions, potentially preventing acute cardiovascular ischemic events. Variability in the transformation of vitamin D into 1,25(OH)2D has b ...