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- Author:
- Yangali-Quintanilla, Victor; Sadmani, Anwar; McConville, Megan; Kennedy, Maria; Amy, Gary
- Source:
- Water research 2010 v.44 no.2 pp. 373-384
- ISSN:
- 0043-1354
- Subject:
- water pollution; endocrine-disrupting chemicals; quantitative structure-activity relationships; pollution control; drugs; nanotechnology; principal component analysis; least squares; pollutants; model validation; filtration; hydrophobicity; molecular weight; databases; pesticides; prediction
- DOI:
- 10.1016/j.watres.2009.06.054
- PubMed:
- 19616272
- https://doi.org/10.1016/j.watres.2009.06.054
- Author:
- Dongqi Wang; Haoduo Zhao; Xunchang Fei; Shane Allen Synder; Mingliang Fang; Min Liu
- Source:
- Environment international 2021 v.155 pp. 106701
- ISSN:
- 0160-4120
- Subject:
- analytical methods; biotransformation; bisphenol A; bisphenol S; databases; endocrine-disrupting chemicals; environment; environmental protection; epoxides; humans; hydrolysis; metabolites; pollutants; toxicity
- Abstract:
- ... Bisphenol A diglycidyl ether (BADGE)-based epoxy resin is one of the most widely used epoxy resins with an annual production amount of several million tons. Compared with all other legacy or emerging organic compounds, BADGE is special due to its toxicity and high reactivity in the environment. More and more studies are available on its analytical methods, occurrence, transformation and toxicity. ...
- DOI:
- 10.1016/j.envint.2021.106701
- https://doi.org/10.1016/j.envint.2021.106701
- Author:
- Bagavathy Shanmugam Karthikeyan; Janani Ravichandran; Karthikeyan Mohanraj; R.P. Vivek-Ananth; Areejit Samal
- Source:
- Science of the total environment 2019 v.692 pp. 281-296
- ISSN:
- 0048-9697
- Subject:
- adverse effects; chemical structure; databases; endocrine-disrupting chemicals; genes; homeostasis; humans; models; physicochemical properties; rodents; social welfare; toxicity
- Abstract:
- ... Human well-being can be affected by exposure to several chemicals in the environment. One such group is endocrine disrupting chemicals (EDCs) that can perturb the hormonal homeostasis leading to adverse health effects. In this work, we have developed a detailed workflow to identify EDCs with supporting evidence of endocrine disruption in published experiments in humans or rodents. Thereafter, this ...
- DOI:
- 10.1016/j.scitotenv.2019.07.225
- https://doi.org/10.1016/j.scitotenv.2019.07.225
- Author:
- van Dyk, J.C.; Pieterse, G.M.
- Source:
- Journal of applied ichthyology 2008 v.24 no.4 pp. 415-422
- ISSN:
- 0175-8659
- Subject:
- Clarias gariepinus; Leydig cells; Sertoli cells; aquariums; blood vessels; catfish; databases; developmental stages; endocrine-disrupting chemicals; estrogens; fish culture; freshwater fish; indicator species; males; osmosis; spawning; spermatids; spermatocytes; spermatogenesis; spermatogonia; spermatozoa; toxic substances; toxicity; South Africa
- Abstract:
- ... The sharptooth catfish (Clarias gariepinus) has recently been shown to be a useful indicator species of oestrogen polluted waters in South Africa ( Barnhoorn et al., 2004 ). Knowledge of the normal reproductive biology of this species is important to be able to assess the morphological changes caused by the exposure to potentially harmful toxicants including endocrine disruptor chemicals (EDCs). E ...
- DOI:
- 10.1111/j.1439-0426.2008.01127.x
- https://doi.org/10.1111/j.1439-0426.2008.01127.x
- Author:
- le Maire, Albane; Bourguet, William; Balaguer, Patrick
- Source:
- Cellular and molecular life sciences 2010 v.67 no.8 pp. 1219-1237
- ISSN:
- 1420-682X
- Subject:
- adverse effects; biosynthesis; crystal structure; databases; diethylstilbestrol; drugs; endocrine system; endocrine-disrupting chemicals; hormone receptors; pollutants; signal transduction
- Abstract:
- ... Endocrine-disrupting chemicals (EDCs) represent a broad class of exogenous substances that cause adverse effects in the endocrine system by interfering with hormone biosynthesis, metabolism, or action. The molecular mechanisms of EDCs involve different pathways including interactions with nuclear hormone receptors (NHRs) which are primary targets of a large variety of environmental contaminants. H ...
- DOI:
- 10.1007/s00018-009-0249-2
- https://doi.org/10.1007/s00018-009-0249-2
- Author:
- Young Ran Kim; Rosana E. Pacella; Fiona A. Harden; Nicole White; Leisa-Maree L. Toms
- Source:
- Environmental research 2019 v.171 pp. 119-133
- ISSN:
- 0013-9351
- Subject:
- at-risk population; cohort studies; databases; endocrine-disrupting chemicals; environmental impact; fecundity; hexabromocyclododecane; humans; issues and policy; organophosphorus compounds; phthalates; pollutants; polybrominated diphenyl ethers; pregnancy; risk; systematic review
- Abstract:
- ... Emerging scientific evidence suggests that exposure to environmental pollutants is associated with negative effects on fecundity as measured by time to pregnancy (TTP).To conduct a systematic review of the literature on the association between selected endocrine disrupting chemicals (EDCs), and fecundity as measured by TTP in humans. Compounds included in this review are: brominated flame retardan ...
- DOI:
- 10.1016/j.envres.2018.12.065
- https://doi.org/10.1016/j.envres.2018.12.065
- Author:
- Jun Chul Park; Jeonghoon Han; Min-Chul Lee; Hye-Min Kang; Chang-Bum Jeong; Dae-Sik Hwang; Minghua Wang; Jae-Seong Lee
- Source:
- Aquatic toxicology 2017 v.186 pp. 105-112
- ISSN:
- 0166-445X
- Subject:
- reactive oxygen species; signal transduction; genes; population growth; mitogen-activated protein kinase; oxidative stress; aquatic ecosystems; adults; longevity; fecundity; glutathione transferase; toxicology; transcriptome; databases; endocrine-disrupting chemicals; oxidants; antioxidant activity; Brachionus; adverse effects; aquatic organisms; glutathione-disulfide reductase
- Abstract:
- ... 2,2′,4,4′-Tetrabromodiphenyl ether (BDE-47) is widely dispersed endocrine disrupting chemicals (EDCs) in the aquatic ecosystem. Due to its devastating effect on marine organisms and insufficient database on toxicology, we investigated the adverse effects of BDE-47 on life parameters and antioxidant defense system following the reactive oxygen species (ROS) production in the monogonont rotifer Brac ...
- DOI:
- 10.1016/j.aquatox.2017.02.025
- https://doi.org/10.1016/j.aquatox.2017.02.025
- Author:
- Eun Shil Cha; Mihye Jeong; Won Jin Lee
- Source:
- Journal of agromedicine 2014 v.19 no.3 pp. 281-293
- ISSN:
- 1545-0813
- Subject:
- European Union; United States Environmental Protection Agency; World Health Organization; active ingredients; acute toxicity; carcinogenicity; databases; endocrine-disrupting chemicals; fungicides; insecticides; mancozeb; oils; organophosphorus compounds; paraquat; pesticide law; prioritization; public health; South Korea; United States
- Abstract:
- ... This study aims to review agricultural pesticide usage and trends and to identify hazardous pesticides for regulation, in terms of public health, in South Korea. The authors collected data on usage and trends of agricultural pesticides through agriculture-related databases. Criteria from the US Environmental Protection Agency classification for carcinogenicity, World Health Organization classifica ...
- DOI:
- 10.1080/1059924X.2014.917349
- https://doi.org/10.1080/1059924X.2014.917349
- Author:
- Sayed Esmaeil Mousavi; Heresh Amini; Pouria Heydarpour; Fatemeh Amini Chermahini; Lode Godderis
- Source:
- Environment international 2019 v.122 pp. 67-90
- ISSN:
- 0160-4120
- Subject:
- World Health Organization; adverse effects; air pollution; biochemical pathways; blood serum; calcitriol; calcium; cholecalciferol; cytochrome P-450; databases; diet; endocrine system; endocrine-disrupting chemicals; environmental exposure; enzymes; gene expression regulation; genes; guidelines; heavy metals; homeostasis; human health; industry; intestines; metabolism; metabolites; parathyroid hormone; particulates; photons; thyroid hormones; tissues; ultraviolet radiation; vitamin D deficiency; weight gain
- Abstract:
- ... Beyond vitamin D (VD) effect on bone homeostasis, numerous physiological functions in human health have been described for this versatile prohormone. In 2016, 95% of the world's population lived in areas where annual mean ambient particulate matter (<2.5 μm) levels exceeded the World Health Organization guideline value (Shaddick et al., 2018). On the other hand, industries disperse thousands of ch ...
- DOI:
- 10.1016/j.envint.2018.11.052
- https://doi.org/10.1016/j.envint.2018.11.052
- Author:
- Jianjun Li; Gehui Wang
- Source:
- Atmospheric research 2015 v.154 pp. 138-145
- ISSN:
- 0169-8095
- Subject:
- aerosols; air; air pollution; bisphenol A; burning; cities; combustion; databases; developed countries; endocrine-disrupting chemicals; evaporation; phthalates; pollution control; seasonal variation; solid wastes; summer; temperature; urban areas; winter; China
- Abstract:
- ... Phthalate esters and bisphenol A (BPA) are endocrine disrupting compounds (EDCs) and ubiquitously occur in the environment. In the past decade we have characterized atmospheric organic aerosols from various environments (e.g., urban, rural, mountain and marine) of East Asia on a molecular level, but not investigated EDCs in the samples. In the current study we re-analyzed our database for concentr ...
- DOI:
- 10.1016/j.atmosres.2014.11.013
- https://doi.org/10.1016/j.atmosres.2014.11.013
- Author:
- Katja Schmidt; Michael Bau; Gila Merschel; Nathalie Tepe
- Source:
- Science of the total environment 2019 v.687 pp. 1401-1408
- ISSN:
- 0048-9697
- Subject:
- carbonated beverages; cerium; cities; databases; drugs; endocrine-disrupting chemicals; fast food restaurants; fast foods; filtration; food chain; gadolinium; groundwater; lutetium; magnetic resonance imaging; pollutants; pollution; syrups; tap water; valleys; wastes; wastewater treatment; wells; xenobiotics; ytterbium; Germany
- Abstract:
- ... Gadolinium-based contrast agents used in magnetic resonance imaging are difficult to impossible to remove in wastewater treatment plants, and may enter groundwater production wells and hence municipal tap water via bank filtration. As anthropogenic gadolinium (Gd) may be accompanied by other, more harmful waste water-derived (micro)pollutants such as endocrine disruptors, we investigated the poten ...
- DOI:
- 10.1016/j.scitotenv.2019.07.075
- https://doi.org/10.1016/j.scitotenv.2019.07.075
- Author:
- Qi Zhong; Meifang Peng; Jialiu He; Wanjun Yang; Fen Huang
- Source:
- Science of the total environment 2020 v.703 pp. 134720
- ISSN:
- 0048-9697
- Subject:
- antibacterial properties; benzophenones; birth weight; bisphenol A; cohort studies; confidence interval; databases; developed countries; endocrine-disrupting chemicals; experimental design; fetal development; human health; maternal exposure; meta-analysis; pollutants; regression analysis; systematic review; triclosan
- Abstract:
- ... Phenols and parabens are endocrine-disrupting chemicals and are widely used in daily life products due to their antibacterial action. Previous studies suggest associations of prenatal exposure to phenols and parabens with fetal development; however, such findings are rare and inconsistent. The aim of this review and meta-analysis is to estimate the associations between maternal exposure to phenols ...
- DOI:
- 10.1016/j.scitotenv.2019.134720
- https://doi.org/10.1016/j.scitotenv.2019.134720
- Author:
- Komodo Matta; Stéphane Ploteau; Xavier Coumoul; Meriem Koual; Bruno Le Bizec; Jean-Philippe Antignac; German Cano-Sancho
- Source:
- Environment international 2019 v.124 pp. 400-407
- ISSN:
- 0160-4120
- Subject:
- databases; endocrine-disrupting chemicals; endometrium; environmental assessment; environmental health; female genital diseases; health effects assessments; humans; in vitro studies; meta-analysis; models; pathogenesis; risk; systematic review; toxicology
- Abstract:
- ... Endometriosis is a hormone-dependent gynaecological disease characterised by the presence and growth of endometrial tissues outside of the uterus. There is growing experimental evidence that suggests environmental endocrine disrupting chemicals, specifically organochlorine chemicals (OCCs), may play a role in the pathogenesis of endometriosis, but to date, there are no studies attempting to gather ...
- DOI:
- 10.1016/j.envint.2018.12.063
- https://doi.org/10.1016/j.envint.2018.12.063
- Author:
- Heli K. Vari; Marja I. Roslund; Sami Oikarinen; Noora Nurminen; Riikka Puhakka; Anirudra Parajuli; Mira Grönroos; Nathan Siter; Olli H. Laitinen; Heikki Hyöty; Juho Rajaniemi; Anna-Lea Rantalainen; Aki Sinkkonen; the ADELE research group
- Source:
- Chemosphere 2021 v.265 pp. 128965
- ISSN:
- 0045-6535
- Subject:
- air; air pollution; bioaccumulation; databases; digestive system; elderly; endocrine system; endocrine-disrupting chemicals; equipment; geographic information systems; humans; intestinal microorganisms; land cover; metagenomics; people; peroxisome proliferator-activated receptors
- Abstract:
- ... There is evidence that polycyclic aromatic hydrocarbons (PAHs) and human gut microbiota are associated with the modulation of endocrine signaling pathways. Independently, studies have found associations between air pollution, land cover and commensal microbiota. We are the first to estimate the interaction between land cover categories associated with air pollution or purification, PAH levels and ...
- DOI:
- 10.1016/j.chemosphere.2020.128965
- https://doi.org/10.1016/j.chemosphere.2020.128965
- Author:
- V. K. Bhatnagar; A. B. Karnik; A. M. Suthar; S. S. A. Zaidi; R. Kashyap; M. P. Shah; P. K. Kulkarni; H. N. Saiyed
- Source:
- Bulletin of environmental contamination and toxicology 2002 v.68 no.1 pp. 22-28
- ISSN:
- 0007-4861
- Subject:
- World Health Organization; active ingredients; adjuvants; adverse effects; at-risk population; bolts; concentrating; cross-sectional studies; databases; developing countries; emulsifiable concentrates; endocrine-disrupting chemicals; endosulfan; farmers; health care workers; hormones; humans; labor; laboratory animals; lindane; models; monitoring; monocrotophos; parathion; phorate; prices; public health; quinalphos; risk; screening; society; solvents; toxic substances; vector-borne diseases; wildlife; India
- Abstract:
- ... Pesticides are toxic chemicals but their benefits to society are undeniably great. These chemicals enhance the economic potential in terms of increased agricultural output and eradication of vector borne diseases but the success has extricated a price in terms of adverse effects on human and environmental health (White 1990; Koh and Jeyaratnam 1996). Production of technical grade pesticides and th ...
- DOI:
- 10.1007/s00128-001-0214-8
- PubMed:
- 11731827
- https://doi.org/10.1007/s00128-001-0214-8
- Author:
- Elena Salamanca-Fernández; Miguel Rodríguez-Barranco; Dafina Petrova; Nerea Larrañaga; Marcela Guevara; Conchi Moreno-Iribas; Maria Dolores Chirlaque; Sandra Colorado-Yohar; Juan Pedro Arrebola; Fernando Vela; Nicolás Olea; Antonio Agudo; Maria-José Sánchez
- Source:
- Chemosphere 2020 v.261 pp. 127697
- ISSN:
- 0045-6535
- Subject:
- bisphenol A; blood serum; chemical analysis; databases; detection; endocrine-disrupting chemicals; geometry; mortality; myocardial infarction; nutrition; patients; population; prospective studies; regression analysis; risk; sampling
- Abstract:
- ... Cardiovascular disease, particularly ischemic heart disease (IHD), is the leading cause of mortality worldwide. Bisphenol A (BPA) is considered an endocrine disruptor and obesogen, present in numerous products of daily use. The aim of this study was to assess the potential association of serum BPA concentrations and the risk of incident IHD in a sub-cohort of the Spanish European Prospective Inves ...
- DOI:
- 10.1016/j.chemosphere.2020.127697
- https://doi.org/10.1016/j.chemosphere.2020.127697
- Author:
- Onur Kenan Ulutaş; İsmet Çok; Feyza Darendeliler; Banu Aydin; Asuman Çoban; Bernhard Henkelmann; Karl-Werner Schramm
- Source:
- Environmental science and pollution research international 2015 v.22 no.24 pp. 19896-19904
- ISSN:
- 0944-1344
- Subject:
- DDE (pesticide); DDT (pesticide); HCH (pesticide); acceptable risk; blood; boys; children; databases; endocrine-disrupting chemicals; endosulfan; hexachlorobenzene; humans; laws and regulations; lindane; lipids; mass spectrometry; milk; neonates; neoplasms; persistent organic pollutants; polychlorinated biphenyls; risk assessment; Turkey (country)
- Abstract:
- ... Even early life in utero cannot provide a safe place for newborns. The first acquaintance with chemicals takes place in utero and/or with mother’s milk after delivery. Besides legislations and bans to persistent organic pollutants (POPs), these chemicals are still affecting the general population especially the children as they are one of the populations most susceptible to chemicals, and also the ...
- DOI:
- 10.1007/s11356-015-5179-y
- https://doi.org/10.1007/s11356-015-5179-y
- Author:
- Onur Kenan Ulutaş; Ismet Çok; Feyza Darendeliler; Banu Aydin; Asuman Çoban; Bernhard Henkelmann; Karl-Werner Schramm
- Source:
- Environmental monitoring and assessment 2015 v.187 no.3 pp. 132
- ISSN:
- 0167-6369
- Subject:
- adipose tissue; blood; breast milk; databases; endocrine-disrupting chemicals; humans; longevity; mass spectrometry; organochlorine pesticides; persistent organic pollutants; pesticide residues; polychlorinated biphenyls; women; Turkey (country)
- Abstract:
- ... The human body is not a chemically uncontaminated system. Every simple action that humans undertake, such as drinking water, eating, nursing, and even breathing air, puts the system under environmental xenobiotic exposure stress. Environmental chemicals have been shown to produce unwanted effects on health and remove the right to healthy living, starting from the first encounter in utero to geriat ...
- DOI:
- 10.1007/s10661-015-4358-0
- https://doi.org/10.1007/s10661-015-4358-0
- Author:
- H.T. Wan; P.Y. Leung; Y.G. Zhao; X. Wei; M.H. Wong; Chris K.C. Wong
- Source:
- Journal of hazardous materials 2013 v.261 pp. 763-769
- ISSN:
- 0304-3894
- Subject:
- bisphenol A; blood plasma; databases; endocrine-disrupting chemicals; exposure pathways; gas chromatography-mass spectrometry; high performance liquid chromatography; humans; males; monitoring; perfluorocarbons; phthalates; risk; tandem mass spectrometry; China
- Abstract:
- ... In this study we report the human plasma concentrations of some common endocrine disrupting chemicals (EDCs) in the Hong Kong population. We have analyzed 153 plasma samples for the contaminants by methods involving labeled standards spiked into the samples. Quantification was performed using high performance liquid chromatography tandem mass spectrometry for bisphenol-A (BPA) and perfluorinated c ...
- DOI:
- 10.1016/j.jhazmat.2013.01.034
- https://doi.org/10.1016/j.jhazmat.2013.01.034
- Author:
- Taboureau, Olivier; Nielsen, Sonny Kim; Audouze, Karine; Weinhold, Nils; Edsgärd, Daniel; Roque, Francisco S.; Kouskoumvekaki, Irene; Bora, Alina; Curpan, Ramona; Jensen, Thomas Skøt; Brunak, Søren; Oprea, Tudor I.
- Source:
- Nucleic acids research 2011 v.39 no.suppl_1 pp. D367
- ISSN:
- 0305-1048
- Subject:
- antidepressants; bisphenol A; bone formation; databases; endocrine-disrupting chemicals; humans; leukemia; nucleic acids; pharmacology; protein-protein interactions; proteins
- Abstract:
- ... Systems pharmacology is an emergent area that studies drug action across multiple scales of complexity, from molecular and cellular to tissue and organism levels. There is a critical need to develop network-based approaches to integrate the growing body of chemical biology knowledge with network biology. Here, we report ChemProt, a disease chemical biology database, which is based on a compilation ...
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