Subject: evolution and antibiotics - PubAg Search Results

1. Changes in the Oxidative Stress Status of Dogs Affected by Acute Enteropathies

Author:: Alessia Candellone; Flavia Girolami; Paola Badino; Watanya Jarriyawattanachaikul; Rosangela Odore
Source:: Veterinary sciences 2022 v.9 no.6 pp. -
ISSN:: 2306-7381
Subject:: antibiotics; antioxidant activity; blood serum; diarrhea; dogs; evolution; oxidative stress; patients; reactive oxygen species; therapeutics
Abstract:: ... Canine acute enteropathies (AE) are common morbidities primarily managed with supportive therapy. However, in some cases, unnecessary courses of antibiotics are empirically prescribed. Recent studies in humans have hypothesized the use of antioxidants as a possible alternative and/or support to antimicrobial drugs in uncomplicated cases. Considering the global need to reduce the antibiotic use, th ...
DOI:: 10.3390/vetsci9060276
: https://doi.org/10.3390/vetsci9060276

2. Differences in recipient ability of uropathogenic Escherichia coli strains in relation with their pathogenic potential

Author:: Marina V. Kuznetsova; Irina L. Maslennikova; Julia S. Pospelova; Darja Žgur Bertok; Marjanca Starčič Erjavec
Source:: Infection, genetics, and evolution 2022 v.97 pp. 105160
ISSN:: 1567-1348
Subject:: antibiotics; bacteriocins; biofilm; biomass; evolution; infection; plankton; plasmids; urinary tract; uropathogenic Escherichia coli; virulence
Abstract:: ... Conjugation is recognized as a mechanism driving dissemination of antibacterial resistances and virulence factors among bacteria. In the presented work conjugative transfer frequency into clinical uropathogenic Escherichia coli strains (UPEC) isolated from patients with symptomatic urinary tract infections was investigated. From 93 obtained UPEC strains only 29 were suitable for conjugation experi ...
DOI:: 10.1016/j.meegid.2021.105160
: https://doi.org/10.1016/j.meegid.2021.105160

3. Dissecting the roles of conductive materials in attenuating antibiotic resistance genes: Evolution of physiological features and bacterial community

Author:: Qi Zhao; Wanqian Guo; Haichao Luo; Huazhe Wang; Taiping Yu; Banghai Liu; Qishi Si; Nanqi Ren
Source:: Journal of hazardous materials 2022 v.438 pp. 129411
ISSN:: 0304-3894
Subject:: anaerobic digesters; antibiotic resistance; antibiotics; bacterial communities; cell communication; evolution; iron; magnetite; oxidative stress; secretion; stress response; sulfamethoxazole; wastewater; wastewater treatment
Abstract:: ... Supplying conductive materials (CMs) into anaerobic bioreactors is considered as a promising technology for antibiotic wastewater treatment. However, whether and how CMs influence antibiotic resistance genes (ARGs) spread remains poorly known. Here, we investigated the effects of three CMs, i.e., magnetite, activated carbon (AC), and zero valent iron (ZVI), on ARGs dissemination during treating su ...
DOI:: 10.1016/j.jhazmat.2022.129411
: https://doi.org/10.1016/j.jhazmat.2022.129411

4. Metagenomic insights into the profile of antibiotic resistomes in sediments of aquaculture wastewater treatment system

Author:: Jianfei Chen; Yuyin Yang; Xinshu Jiang; Yanchu Ke; Tao He; Shuguang Xie
Source:: Journal of environmental sciences (China) 2022 v.113 pp. 345-355
ISSN:: 1001-0742
Subject:: Acinetobacter; Escherichia; Klebsiella; Pseudomonas; antibiotic residues; antibiotic resistance; antibiotic resistance genes; antibiotics; aquaculture; bacterial communities; crabs; evolution; horizontal gene transfer; metagenomics; plasmids; risk; sediments; wastewater; wastewater treatment; China
Abstract:: ... To meet the rapidly growing global demand for aquaculture products, large amounts of antibiotics were used in aquaculture, which might accelerate the evolution of antibiotic-resistant bacteria (ARB) and the propagation of antibiotic genes (ARGs). In our research, we revealed the ARGs profiles, their co-occurrence with mobile genetic elements (MGEs), and potential hosts in sediments of a crab pond ...
DOI:: 10.1016/j.jes.2021.06.026
: https://doi.org/10.1016/j.jes.2021.06.026

5. Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches

Author:: Christopher Mutuku; Zoltan Gazdag; Szilvia Melegh
Source:: World journal of microbiology & biotechnology 2022 v.38 no.9 pp. 152
ISSN:: 0959-3993
Subject:: antibiotic resistance; antibiotics; biotechnology; chronic exposure; evolution; hospitals; phage therapy; wastewater; wastewater treatment; water quality
Abstract:: ... Antimicrobial pharmaceuticals are classified as emergent micropollutants of concern, implying that even at low concentrations, long-term exposure to the environment can have significant eco-toxicological effects. There is a lack of a standardized regulatory framework governing the permissible antibiotic content for monitoring environmental water quality standards. Therefore, indiscriminate dischar ...
DOI:: 10.1007/s11274-022-03334-0
: https://doi.org/10.1007/s11274-022-03334-0

6. Suppressing evolution of antibiotic resistance through environmental switching

Author:: Bryce Morsky; Dervis Can Vural
Source:: Theoretical ecology 2022 v.15 no.2 pp. 115-127
ISSN:: 1874-1738
Subject:: antibiotic resistance; antibiotics; ecology; evolution; medicine; models; mutants; pharmacodynamics
Abstract:: ... Ecology and evolution under changing environments are important in many subfields of biology with implications for medicine. Here, we explore an example: the consequences of fluctuating environments on the emergence of antibiotic resistance, which is an immense and growing problem. Typically, high doses of antibiotics are employed to eliminate the infection quickly and minimize the time under whic ...
DOI:: 10.1007/s12080-022-00530-4
: https://doi.org/10.1007/s12080-022-00530-4

7. Temporin B Forms Hetero-Oligomers with Temporin L, Modifies Its Membrane Activity, and Increases the Cooperativity of Its Antibacterial Pharmacodynamic Profile

Author:: Philip M. Ferguson; Maria Clarke; Giorgia Manzo; Charlotte K. Hind; Melanie Clifford; J. Mark Sutton; Christian D. Lorenz; David A. Phoenix; A. James Mason
Source:: Biochemistry 2022 v.61 no.11 pp. 1029-1040
ISSN:: 1520-4995
Subject:: Gram-positive bacteria; Rana temporaria; antibacterial properties; antibiotics; antimicrobial peptides; evolution; frogs; histones; molecular dynamics; pharmacodynamics; plasma membrane; probability
Abstract:: ... The pharmacodynamic profile of antimicrobial peptides (AMPs) and their in vivo synergy are two factors that are thought to restrict resistance evolution and ensure their conservation. The frog Rana temporaria secretes a family of closely related AMPs, temporins A–L, as an effective chemical dermal defense. The antibacterial potency of temporin L has been shown to increase synergistically in combin ...
DOI:: 10.1021/acs.biochem.1c00762
: https://doi.org/10.1021/acs.biochem.1c00762

8. Antibiotic resistome in the livestock and aquaculture industries: Status and solutions

Author:: Yi Zhao; Qiu E. Yang; Xue Zhou; Feng-Hua Wang; Johanna Muurinen; Marko P. Virta; Kristian Koefoed Brandt; Yong-Guan Zhu
Source:: Critical reviews in environmental science and technology 2021 v.51 no.19 pp. 2159-2196
ISSN:: 1547-6537
Subject:: One Health initiative; animal production; antibiotic resistance; antibiotic resistance genes; antibiotics; environmental health; environmental science; evolution; human health; humans; livestock; livestock and meat industry; technology
Abstract:: ... Since the introduction of antibiotics into clinical practices in the 1940s, antibiotics have become an integral part of animal production to meet the increasing human demand for animal-derived foods. As a result, industrial-scale animal production has emerged as a hotspot for the evolution and dissemination of antibiotic resistance genes (ARGs), thereby potentially contributing to a looming public ...
DOI:: 10.1080/10643389.2020.1777815
: https://doi.org/10.1080/10643389.2020.1777815

9. Distribution and transfer of antibiotic resistance genes in different soil–plant systems

Author:: Yuan Zhang; Jie Zhou; Jian Wu; Qianwen Hua; Canxin Bao
Source:: Environmental science and pollution research 2022 v.29 no.39 pp. 59159-59172
ISSN:: 0944-1344
Subject:: Brassica rapa subsp. chinensis; Echinochloa crus-galli; Firmicutes; animal manures; antibiotic resistance; antibiotics; bacterial communities; corn; dogs; endophytes; evolution; food chain; human health; lettuce; phyllosphere; research; rhizosphere; soil; soil pollution; tail
Abstract:: ... The extensive application of farm manure that is contaminated with pharmaceutical antibiotics not only causes substantial soil pollution but additionally leads to the input of antibiotic resistance genes (ARGs) into the soil. These ARGs would proliferate and affect human health via the food chain. The effects of cultivated crops and wild plants on ARGs in rhizosphere soil are unclear. Therefore, w ...
DOI:: 10.1007/s11356-021-17465-8
: https://doi.org/10.1007/s11356-021-17465-8

10. Effects of various antibiotics on aerobic nitrogen removal and antibiotic degradation performance: Mechanism, degradation pathways, and microbial community evolution

Author:: Donghui Liang; Yongyou Hu; Ruzhen Huang; Jianhua Cheng; Yuancai Chen
Source:: Journal of hazardous materials 2022 v.422 pp. 126818
ISSN:: 0304-3894
Subject:: Achromobacter; activated sludge; amination; antibiotic resistance; antibiotics; biofilm; ciprofloxacin; cleavage (chemistry); denitrification; evolution; hydroxylation; methylation; microbial communities; nitrification; nitrogen; pollutants; sulfamethoxazole; total nitrogen; trimethoprim
Abstract:: ... Little information about the selective stress of various antibiotics and how they influence different stages of aerobic nitrogen removal is available. A long-term aerobic nitrogen removal-moving bed biofilm reactor was established by the inoculation of Achromobacter sp. JL9, capable of heterotrophic nitrification and aerobic denitrification, and aerobic activated sludge. The nitrogen removal and a ...
DOI:: 10.1016/j.jhazmat.2021.126818
: https://doi.org/10.1016/j.jhazmat.2021.126818

11. Enhancing recovery performance of the toluene-removing biofilter after the short/long interference-shutdown period

Author:: Yuxi Yan; Bixi Zhao; Jiao Yang; Jing Zhang; Shunyi Li; Yu Xia
Source:: Bioresource technology 2022 v.346 pp. 126592
ISSN:: 0960-8524
Subject:: Pseudomonas putida; antibiotics; biodegradation; biofilters; drug resistance; evolution; industrial applications; microbial communities; polyethylene; risk; starvation; technology; tinidazole
Abstract:: ... In this study, the feasibility of three methods on enhancing the recovery performance of biofilter after the interference and starvation periods was evaluated. Results show that despite the pressure drop risk, supplementation of 7.5% (w/v) Polyethylene glycol-600 (PEG-600) resulted in quick recovery on removal efficiency in both short- and long-term interference shutdown experiments. Tinidazole Ta ...
DOI:: 10.1016/j.biortech.2021.126592
: https://doi.org/10.1016/j.biortech.2021.126592

12. Impact of bacterial persisters on their host

Author:: Ana L Moldoveanu; Julian A Rycroft; Sophie Helaine
Source:: Current opinion in microbiology 2021 v.59 pp. 65-71
ISSN:: 1369-5274
Subject:: antibiotic resistance; antibiotics; bacteria; biosynthesis; evolution; immune response; pathogen survival
Abstract:: ... The rise of antibiotic failure poses a severe threat to global health. There is growing concern that this failure is not solely driven by stable antibiotic resistance but also by a subpopulation of transiently non-growing, antibiotic tolerant bacteria. These ‘persisters’ have been proposed to seed relapsing infections, an important clinical outcome of treatment failure — although definitive eviden ...
DOI:: 10.1016/j.mib.2020.07.006
: https://doi.org/10.1016/j.mib.2020.07.006

13. Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements

Author:: Andrés Santos; Felipe Burgos; Jaime Martinez-Urtaza; Leticia Barrientos
Source:: Microorganisms 2022 v.10 no.7 pp. -
ISSN:: 2076-2607
Subject:: Pseudomonas; Psychrobacter; Staphylococcus; antibiotic resistance; antibiotics; evolution; metagenomics; soil; taxonomy; Antarctic region; Antarctica
Abstract:: ... Antibiotic resistance genes (ARGs) are undergoing a remarkably rapid geographic expansion in various ecosystems, including pristine environments such as Antarctica. The study of ARGs and environmental resistance genes (ERGs) mechanisms could provide a better understanding of their origin, evolution, and dissemination in these pristine environments. Here, we describe the diversity of ARGs and ERGs ...
DOI:: 10.3390/microorganisms10071432
: https://doi.org/10.3390/microorganisms10071432

14. Molecular basis of cycloheximide resistance in the Ophiostomatales revealed

Author:: Brenda D. Wingfield; Mike J. Wingfield; Tuan A. Duong
Source:: Current genetics 2022 v.68 no.3-4 pp. 505-514
ISSN:: 0172-8083
Subject:: Kluyveromyces; Ophiostomatales; antibiotics; cycloheximide; evolution; genes; glutamine; mutation; ribosomal proteins; yeasts
Abstract:: ... Resistance to the antibiotic Cycloheximide has been reported for a number of fungal taxa. In particular, some yeasts are known to be highly resistant to this antibiotic. Early research showed that this resulted from a transition mutation in one of the 60S ribosomal protein genes. In addition to the yeasts, most genera and species in the Ophiostomatales are highly resistant to this antibiotic, whic ...
DOI:: 10.1007/s00294-022-01235-1
: https://doi.org/10.1007/s00294-022-01235-1

15. Occurrences, transport drivers, and risk assessments of antibiotics in typical oasis surface and groundwater

Author:: Shixue Wu; Pei Hua; Dongwei Gui; Jin Zhang; Guangguo Ying; Peter Krebs
Source:: Water research 2022 v.225 pp. 119138
ISSN:: 0043-1354
Subject:: antibiotic resistance; antibiotics; aquatic organisms; ciprofloxacin; dissolved oxygen; environmental assessment; evaporation; evolution; groundwater; norfloxacin; oases; redox potential; research; risk; surface water; water storage; China
Abstract:: ... Intensive use of antibiotics affects biogeochemical cycles and stimulates the evolution of antibiotic resistance, thus threatening global health and social development. The spatiotemporal distributions of antibiotics in single aqueous matrices have been widely documented; however, their occurrence in surface–groundwater systems has received less attention, especially in arid regions that usually h ...
DOI:: 10.1016/j.watres.2022.119138
: https://doi.org/10.1016/j.watres.2022.119138

16. Performance of Holstein calves receiving increased nutrient intake through the addition of skim milk or milk replacer powder to the whole milk

Author:: M. Norouzi; Ali A. Alamouti; F. Foroudi; F. Ahmadi; H. Beiranvand
Source:: Animal feed science and technology 2021 v.278 pp. 115013
ISSN:: 0377-8401
Subject:: Holstein; antibiotics; body length; body weight changes; calves; diarrhea; digestibility; digestion; dried skim milk; evolution; feed conversion; females; milk replacer; nutrient intake; skim milk; technology; therapeutics; weight gain; whole milk
Abstract:: ... The purpose of this research was to describe the performance of Holstein calves before and after weaning when total solids in their daily milk were increased with skim milk or milk replacer powder. Forty-five female Holstein calves (body weight = 39.5 ± 1.61 kg) were assigned in random to 1 of 3 treatments: 1) whole milk (WM) with total solids of 123 ± 4.1 g/kg, 2) whole milk + skim milk powder (W ...
DOI:: 10.1016/j.anifeedsci.2021.115013
: https://doi.org/10.1016/j.anifeedsci.2021.115013

17. Unexpected distribution of the 4-formylaminooxyvinylglycine (FVG) biosynthetic pathway in Pseudomonas and beyond

Author:: Davis Edward W.2nd; Okrent Rachel A.; Manning Viola A.; Trippe Kristin M.
Source:: PloS one 2021 v.16 no.4 pp. e0247348
ISSN:: 1932-6203
Subject:: Burkholderia; Pantoea; Pseudomonas fluorescens; Thiomonas; antibiotics; biochemical pathways; biosynthesis; evolution; genetic traits; genomics; herbicides; horizontal gene transfer; mass spectrometry; metabolites; multigene family
Abstract:: ... The biological herbicide and antibiotic 4-formylaminooxyvinylglycine (FVG) was originally isolated from several rhizosphere-associated strains of Pseudomonas fluorescens. Biosynthesis of FVG is dependent on the gvg biosynthetic gene cluster in P. fluorescens. In this investigation, we used comparative genomics to identify strains with the genetic potential to produce FVG due to presence of a gvg g ...
Handle:: 10113/7665484
DOI:: 10.1371/journal.pone.0247348
: https://doi.org/10.1371/journal.pone.0247348

18. Urbanization drives the succession of antibiotic resistome and microbiome in a river watershed

Author:: Longji Zhu; Ruilong Li; Yu Yan; Li Cui
Source:: Chemosphere 2022 v.301 pp. 134707
ISSN:: 0045-6535
Subject:: antibiotic resistance; antibiotic resistance genes; antibiotics; aquatic environment; ecosystems; environmental assessment; evolution; humans; microbiome; multiple drug resistance; population size; regression analysis; risk; rivers; sediments; urban areas; urbanization; watersheds
Abstract:: ... Urbanization is a process of ecosystem evolution mediated by human activities. One of the main consequences is the alteration of antibiotic resistome and microbiome in aquatic environment, which may transfer from water to sediments and exert a long-term health concern to aquatic animals and even humans. However, the role of urbanization in shaping resistome and microbiome in water and sediments is ...
DOI:: 10.1016/j.chemosphere.2022.134707
: https://doi.org/10.1016/j.chemosphere.2022.134707

19. The evolutionary trade‐offs in phage‐resistant Klebsiella pneumoniae entail cross‐phage sensitization and loss of multidrug resistance

Author:: Grazyna Majkowska‐Skrobek; Pawel Markwitz; Ewelina Sosnowska; Cédric Lood; Rob Lavigne; Zuzanna Drulis‐Kawa
Source:: Environmental microbiology 2021 v.23 no.12 pp. 7723-7740
ISSN:: 1462-2912
Subject:: Klebsiella pneumoniae; antibiotics; bacteriophages; biosynthesis; complement; cross resistance; evolution; exopolysaccharides; genomics; innate immunity; multiple drug resistance; mutation; plasmids; therapeutics; virulence
Abstract:: ... Bacteriophage therapy is currently being evaluated as a critical complement to traditional antibiotic treatment. However, the emergence of phage resistance is perceived as a major hurdle to the sustainable implementation of this antimicrobial strategy. By combining comprehensive genomics and microbiological assessment, we show that the receptor‐modification resistance to capsule‐targeting phages i ...
DOI:: 10.1111/1462-2920.15476
: https://doi.org/10.1111/1462-2920.15476

20. Candida albicans, a reservoir of Listeria monocytogenes?

Author:: Susana Castro-Seriche; Alonso Jerez-Morales; Carlos T. Smith; Kimberly Sánchez-Alonzo; Apolinaria García-Cancino
Source:: Infection, genetics, and evolution 2021 v.90 pp. 104779
ISSN:: 1567-1348
Subject:: Candida albicans; DNA; Listeria monocytogenes; agar; antibiotics; chloramphenicol; coculture; evolution; fluorescence; genes; humans; infection; light microscopy; pathogenicity; pathogens; risk; temperature; transmission electron microscopy; viability; yeasts
Abstract:: ... Listeria monocytogenes is a pathogen causing serious or mortal infections in human risk populations. Its infectivity is in part due to its ability to infect diverse eukaryotic cells. Since several bacteria can enter into yeast cells, including Candida albicans, the aims of this work were to evaluate if L. monocytogenes was able to harbor, retaining its viability, within C. albicans cells and to ev ...
DOI:: 10.1016/j.meegid.2021.104779
: https://doi.org/10.1016/j.meegid.2021.104779

21. Complete genome sequence and epigenetic profile of Bacillus velezensis UCMB5140 used for plant and crop protection in comparison with other plant-associated Bacillus strains

Author:: Oleg N. Reva; Safronova A. Larisa; Aneth D. Mwakilili; Donatha Tibuhwa; Sylvester Lyantagaye; Wai Yin Chan; Stefanie Lutz; Christian H. Ahrens; Joachim Vater; Rainer Borriss
Source:: Applied microbiology and biotechnology 2020 v.104 no.17 pp. 7643-7656
ISSN:: 0175-7598
Subject:: Bacillus velezensis; DNA; DNA methylation; adhesins; adhesion; antibiotics; biological control; biopesticides; biotechnology; epigenetics; evolution; gene expression; ligases; methyltransferases; nonribosomal peptides; nucleotide sequences; operon; plant growth-promoting rhizobacteria; plant protection; polypeptides
Abstract:: ... The application of biocontrol biopesticides based on plant growth–promoting rhizobacteria (PGPR), particularly members of the genus Bacillus, is considered a promising perspective to make agricultural practices sustainable and ecologically safe. Recent advances in genome sequencing by third-generation sequencing technologies, e.g., Pacific Biosciences’ Single Molecule Real-Time (PacBio SMRT) platf ...
DOI:: 10.1007/s00253-020-10767-w
: https://doi.org/10.1007/s00253-020-10767-w

22. Composition of nutrient media and temperature of cultivation imposes effect on the content of secondary metabolites of Nocardiopsis sp. isolated from a Siberian Cave

Author:: Denis V. Axenov-Gribanov; Maria M. Morgunova; Ulyana A. Vasilieva; Stanislav V. Gamaiunov; Maria E. Dmitrieva (Krasnova); Ekaterina V. Pereliaeva; Alexander Yu. Belyshenko; Andriy N. Luzhetskyy
Source:: 3 Biotech 2021 v.11 no.8 pp. 386
ISSN:: 2190-572X
Subject:: Bacillus subtilis; Nocardiopsis; Siberia; antibacterial properties; antibiotic resistance; antibiotics; antimicrobial peptides; asparagine; biosynthesis; ecosystems; evolution; human population; hydrophobicity; liquid chromatography; liquids; malt extract; mass spectrometry; secondary metabolites; temperature
Abstract:: ... Growth of human population leads to many global and medical problems. The problems include the crisis of health, antibiotic resistance, drug discovery, etc. Increasing antimicrobial resistance of microorganisms results in the need to screen natural products (incl. antibiotics and antimicrobial peptides) and their producers in different ecological niches. The purpose of this study was to estimate a ...
DOI:: 10.1007/s13205-021-02926-1
: https://doi.org/10.1007/s13205-021-02926-1

23. Development of a Convergent Enantioselective Synthetic Route to (−)-Myrocin G

Author:: Martin Tomanik; Christos Economou; Madeline C. Frischling; Mengzhao Xue; Victoria A. Marks; Brandon Q. Mercado; Seth B. Herzon
Source:: Journal of organic chemistry 2020 v.85 no.14 pp. 8952-8989
ISSN:: 1520-6904
Subject:: DNA; Lewis acids; antibiotics; bioactive properties; chemical reactions; crosslinking; enantioselectivity; evolution; fungi; isomers; mechanism of action; metabolites; organic chemistry
Abstract:: ... Myrocins are a family of antiproliferative antibiotic fungal metabolites possessing a masked electrophilic cyclopropane. Preliminary chemical reactivity studies imputed the bioactivity of these natural products to a DNA cross-linking mechanism, but this hypothesis was not confirmed by studies with native DNA. We recently reported a total synthesis of (−)-myrocin G (4), the putative active form of ...
DOI:: 10.1021/acs.joc.0c00891
: https://doi.org/10.1021/acs.joc.0c00891

24. Energy- and cost-effective non-sterilized fermentation of 2,3-butanediol by an engineered Klebsiella pneumoniae OU7 with an anti-microbial contamination system

Author:: Ze-Wang Guo; Xiao-Yang Ou; Pei Xu; Hui-Fang Gao; Liao-Yuan Zhang; Min-Hua Zong; Wen-Yong Lou
Source:: Green chemistry 2020 v.22 no.24 pp. 8584-8593
ISSN:: 1463-9270
Subject:: Klebsiella pneumoniae; antibiotic resistance; antibiotics; biosynthesis; cost effectiveness; energy; evolution; fermentation; green chemistry; labor; microbial contamination; nitrogen; pathogenicity; phosphorus; risk; urea
Abstract:: ... Microbial contamination is a serious challenge that needs to be overcome for the successful biosynthesis of 2,3-butanediol (2,3-BD). However, traditional strategies such as antibiotic administration or sterilization are costly, have high energy demands, and may increase the risk of antibiotic resistance. Here, we intend to develop a robust strategy to achieve non-sterilized fermentation of 2,3-BD. ...
DOI:: 10.1039/d0gc03044a
: https://doi.org/10.1039/d0gc03044a

25. Evolution of Antibacterial Drug Screening Methods: Current Prospects for Mycobacteria

Author:: Clara M. Bento; Maria Salomé Gomes; Tânia Silva
Source:: Microorganisms 2021 v.9 no.12 pp. -
ISSN:: 2076-2607
Subject:: antibiotics; automation; evolution; prediction
Abstract:: ... The increasing resistance of infectious agents to available drugs urges the continuous and rapid development of new and more efficient treatment options. This process, in turn, requires accurate and high-throughput techniques for antimicrobials’ testing. Conventional methods of drug susceptibility testing (DST) are reliable and standardized by competent entities and have been thoroughly applied to ...
DOI:: 10.3390/microorganisms9122562
: https://doi.org/10.3390/microorganisms9122562

26. Evolution of surviving Streptoccocus pyogenes from pharyngotonsillitis patients submit to multiple cycles of antimicrobial photodynamic therapy

Author:: Jennifer Machado Soares; Natalia Mayumi Inada; Vanderlei Salvador Bagnato; Kate Cristina Blanco
Source:: Journal of photochemistry and photobiology 2020 v.210 pp. 111985
ISSN:: 1011-1344
Subject:: Streptococcus pyogenes; adhesion; antibiotics; biofilm; biomedical research; curcumin; evolution; mortality; photobiology; photochemistry; photochemotherapy; photosensitizing agents
Abstract:: ... It is estimated over 600 million pharyngotonsillitis (PT) cases worldwide per year and 30% of this total are caused by Streptococcus pyogenes with standard antibiotic treatment. Antimicrobial Photodynamic Therapy (aPDT) has been studied for the clinical research in infectious diseases. The study aim was to analyze the evolution of aPDT on inactivation of clinical strains of multiple cycles. S. pyo ...
DOI:: 10.1016/j.jphotobiol.2020.111985
: https://doi.org/10.1016/j.jphotobiol.2020.111985

27. Genome Sequence and Characterization of Five Bacteriophages Infecting Streptomyces coelicolor and Streptomyces venezuelae: Alderaan, Coruscant, Dagobah, Endor1 and Endor2

Author:: Aël Hardy; Vikas Sharma; Larissa Kever; Julia Frunzke
Source:: Viruses 2020 v.12 no.10 pp. -
ISSN:: 1999-4915
Subject:: Siphoviridae; Streptomyces coelicolor; Streptomyces venezuelae; antibiotics; bacteria; bacteriophages; evolution; nucleotide sequences; predation; prediction; sequence analysis; transmission electron microscopy
Abstract:: ... Streptomyces are well-known antibiotic producers, also characterized by a complex morphological differentiation. Streptomyces, like all bacteria, are confronted with the constant threat of phage predation, which in turn shapes bacterial evolution. However, despite significant sequencing efforts recently, relatively few phages infecting Streptomyces have been characterized compared to other genera. ...
DOI:: 10.3390/v12101065
: https://doi.org/10.3390/v12101065

28. Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with Escherichia coli

Author:: Kyle J. Card; Misty D. Thomas; Joseph L. Graves; Jeffrey E. Barrick; Richard E. Lenski
Source:: Proceedings of the National Academy of Sciences 2021 v.118 no.5 pp. -
ISSN:: 1091-6490
Subject:: Escherichia coli; antibiotic resistance; antibiotics; epistasis; evolution; genes; genetic background; genomics; long term experiments; phenotype; statistical analysis
Abstract:: ... Antibiotic resistance is a growing health concern. Efforts to control resistance would benefit from an improved ability to forecast when and how it will evolve. Epistatic interactions between mutations can promote divergent evolutionary trajectories, which complicates our ability to predict evolution. We recently showed that differences between genetic backgrounds can lead to idiosyncratic respons ...
Handle:: 10113/7344752
DOI:: 10.1073/pnas.2016886118
CHORUS:: 10.1073/pnas.2016886118
: https://doi.org/10.1073/pnas.2016886118

29. High frequency and diversity of Vancomycin-resistant Enterococci (VRE) in Algerian healthcare settings

Author:: Hanane Zerrouki; Sid-Ahmed Rebiahi; Linda Hadjadj; Fatmi Ahlem; Yamina Elhabiri; Tahar Sedrati; Jean-Marc Rolain; Seydina M. Diene
Source:: Infection, genetics, and evolution 2021 v.92 pp. 104889
ISSN:: 1567-1348
Subject:: antibiotic resistance; antibiotics; evolution; genes; glycopeptides; health services; hospitals; infection; linezolid
Abstract:: ... The spread of vancomycin-resistant Enterococci (VRE) in Algerian hospital settings is poorly reported. Since the first report in 2006, few data have been available on the molecular mechanism of this resistance across the country. In this study, we investigate the frequency and antibiotic resistance mechanisms of Enterococci strains isolated from hospitalised patients in the Tlemcen university hosp ...
DOI:: 10.1016/j.meegid.2021.104889
: https://doi.org/10.1016/j.meegid.2021.104889

30. High occurrence of heavy metal tolerance genes in bacteria isolated from wastewater: A new concern?

Author:: Guilherme Sgobbi Zagui; Natália Columbaro Moreira; Danilo Vitorino Santos; Ana Lúcia Costa Darini; José L. Domingo; Susana Inés Segura-Muñoz; Leonardo Neves Andrade
Source:: Environmental research 2021 v.196 pp. 110352
ISSN:: 0013-9351
Subject:: Hafnia alvei; Serratia fonticola; antibiotic resistance; antibiotics; antimicrobial properties; arsenic; cadmium; cobalt; drug therapy; evolution; hospitals; human health; mercury(II) reductase; metal tolerance; research; sewage; silver; transporters; wastewater; wastewater treatment; zinc
Abstract:: ... Some heavy metals have antimicrobial activity and are considered as potential alternatives to traditional antibiotic therapy. However, heavy metal tolerance genes (HMTG) have been already detected and coding different tolerance mechanisms. Considering that certain metals are promising for antimicrobial therapy, evaluation of HMTG dissemination in bacteria from sewage is essential to understand the ...
DOI:: 10.1016/j.envres.2020.110352
: https://doi.org/10.1016/j.envres.2020.110352

31. Inhibitory effects of aptamer targeted teicoplanin encapsulated PLGA nanoparticles for Staphylococcus aureus strains

Author:: Samet Ucak; Mert Sudagidan; Baris A. Borsa; Banu Mansuroglu; Veli C. Ozalp
Source:: World journal of microbiology & biotechnology 2020 v.36 no.5 pp. 69
ISSN:: 0959-3993
Subject:: Gram-positive bacteria; Staphylococcus epidermidis; antibiotic resistance; antibiotics; encapsulation; evolution; glycopeptides; methicillin-resistant Staphylococcus aureus; minimum inhibitory concentration; multiple drug resistance; nanoparticles; oligonucleotides; pathogens
Abstract:: ... Emergence of resistance to traditional antibiotic treatments necessitates alternative delivery systems. Teicoplanin is a glycopeptide antibiotic used in the treatments of serious infections caused by Gram-positive bacteria, including Methicillin Resistant Staphylococcus aureus (MRSA). One strategy to keep up with antibiotic resistance development is to limit dose and amount during treatments. Targ ...
DOI:: 10.1007/s11274-020-02845-y
: https://doi.org/10.1007/s11274-020-02845-y

32. Natural and synthetic plant compounds as anti-biofilm agents against Escherichia coli O157:H7 biofilm

Author:: Anuj Rohatgi; Pratima Gupta
Source:: Infection, genetics, and evolution 2021 v.95 pp. 105055
ISSN:: 1567-1348
Subject:: Escherichia coli O157; Gram-negative bacteria; antibiotics; biofilm; drug resistance; evolution; genes; horizontal gene transfer; infection; intestines; lifestyle; microbial communities; pathogens; pathotypes; phytochemicals; plankton; synergism; therapeutics
Abstract:: ... Escherichia coli is a common gram-negative bacterium found in the gut and intestinal tract of warm-blooded animals including humans. An evolved seropathotype E. coli O157:H7 (STEC) came into existence in 1982, since then it has been evolved as a stronger and more robust drug-resistant pathotype of E. coli. This drug resistance is due to horizontal gene transfer, natural gene evolution for survival ...
DOI:: 10.1016/j.meegid.2021.105055
: https://doi.org/10.1016/j.meegid.2021.105055

33. Occurrence of antibiotics and antibiotic resistance genes in the Fuxian Lake and antibiotic source analysis based on principal component analysis-multiple linear regression model

Author:: Bin Zhao; Jiamin Xu; Guodong Zhang; Shaoyong Lu; Xiaohui Liu; Liangxing Li; Ming Li
Source:: Chemosphere 2021 v.262 pp. 127741
ISSN:: 0045-6535
Subject:: anthropogenic activities; antibiotic resistance genes; antibiotics; aquatic organisms; area; correlation; degradation; evolution; humans; lakes; mining; occurrence; ofloxacin; prevalence; regression analysis; risk; rivers; sampling; sulfamethoxazole; sulfanilamide; surface water; tourists
Abstract:: ... In recent years, the dramatic increase in antibiotic use has led to the evolution of antibiotic resistant genes (ARGs), posing a potential risk to human and aquatic ecological safety. In this study, source contribution and correlations between twelve antibiotics and their corresponding ARGs were firstly investigated in surface water in the Fuxian Lake. The results showed that sulfamethoxazole (SMX ...
DOI:: 10.1016/j.chemosphere.2020.127741
: https://doi.org/10.1016/j.chemosphere.2020.127741

34. Pan-proteome profiling of emerging and re-emerging zoonotic pathogen Orientia tsutsugamushi for getting insight into microbial pathogenesis

Author:: Dixit Sharma; Ankita Sharma; Birbal Singh; Shailender Kumar Verma
Source:: Microbial pathogenesis 2021 v.158 pp. 105103
ISSN:: 0882-4010
Subject:: DNA replication; Orientia tsutsugamushi; antibiotic resistance; antibiotics; cell division; evolution; gene expression; metabolism; multiple drug resistance; pathogenesis; pathogens; ribosomes; scrub typhus; therapeutics; virulence
Abstract:: ... With the occurrence and evolution of antibiotic and multidrug resistance in bacteria most of the existing remedies are becoming ineffective. The pan-proteome exploration of the bacterial pathogens helps to identify the wide spectrum therapeutic targets which will be effective against all strains in a species. The current study is focused on the pan-proteome profiling of zoonotic pathogen Orientia ...
DOI:: 10.1016/j.micpath.2021.105103
: https://doi.org/10.1016/j.micpath.2021.105103

35. Quantitative biology of survival under antibiotic treatments

Author:: Asher Brauner; Nathalie Q Balaban
Source:: Current opinion in microbiology 2021 v.64 pp. 139-145
ISSN:: 1369-5274
Subject:: antibiotics; biocides; evolution; growth retardation; microbiology
Abstract:: ... The mathematical formulation for the dynamics of growth reduction and/or killing under antibiotic treatments has a long history. Even before the extensive use of antibiotics, attempts to model the killing dynamics of biocides were made [1]. Here, we review relatively simple quantitative formulations of the two main modes of survival under antibiotics, resistance and tolerance, as well as their het ...
DOI:: 10.1016/j.mib.2021.10.007
: https://doi.org/10.1016/j.mib.2021.10.007

36. The Role of QuantiFERON-TB Gold Plus in Mycobacterium Tuberculosis Detection in a Severe HIV Immunocompromised Patient—Case Report

Author:: Florentina Dumitrescu; Cătălina-Gabriela Pisoschi; Vlad Pădureanu; Andreea Cristina Stoian; Livia Dragonu; Lucian Giubelan
Source:: Pathogens 2021 v.10 no.11 pp. -
ISSN:: 2076-0817
Subject:: HIV infections; Mycobacterium tuberculosis; Pneumocystis; antibiotics; antiretroviral agents; cough; disease prevention; dyspnea; evolution; immunosuppression; opportunistic infection; patients; pneumonia; therapeutics; tuberculosis
Abstract:: ... Tuberculosis (TB) is an important opportunistic infection in HIV-positive people. We are reporting a case of a 31-year-old HIV-infected patient who was hospitalized in July 2021 for dyspnea, cough with mucopurulent sputum and asthenia. He was confirmed to have Serratia liquefaciens pneumonia and acute respiratory failure. The evolution was unfavorable despite the antibiotic, pathogenic and symptom ...
DOI:: 10.3390/pathogens10111523
: https://doi.org/10.3390/pathogens10111523

37. Targeting evolution of antibiotic resistance by SOS response inhibition

Author:: Alexander Yakimov; Irina Bakhlanova; Dmitry Baitin
Source:: Computational and Structural Biotechnology Journal 2021 v.19 pp. 777-783
ISSN:: 2001-0370
Subject:: DNA repair; antibiotic resistance; antibiotics; biotechnology; evolution; homologous recombination; horizontal gene transfer; mutagenesis; therapeutics
Abstract:: ... Antibiotic resistance is acquired in response to antibiotic therapy by activating SOS-depended mutagenesis and horizontal gene transfer pathways. Compounds able to inhibit SOS response are extremely important to develop new combinatorial strategies aimed to block mutagenesis. The regulators of homologous recombination involved in the processes of DNA repair should be considered as potential target ...
DOI:: 10.1016/j.csbj.2021.01.003
: https://doi.org/10.1016/j.csbj.2021.01.003

38. ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life

Author:: Victoriia Murina; Marje Kasari; Hiraku Takada; Mariliis Hinnu; Chayan Kumar Saha; James W. Grimshaw; Takahiro Seki; Michael Reith; Marta Putrinš; Tanel Tenson; Henrik Strahl; Vasili Hauryliuk; Gemma Catherine Atkinson
Source:: Journal of molecular biology 2019 v.431 no.18 pp. 3568-3590
ISSN:: 0022-2836
Subject:: Bacillus subtilis; Escherichia coli; Saccharomyces cerevisiae; adenosinetriphosphatase; ancestry; animal pathogens; antibiotic resistance; antibiotics; evolution; genome; guanosinetriphosphatase; mutants; protein synthesis; ribosomes; transferases
Abstract:: ... Within the larger ABC superfamily of ATPases, ABCF family members eEF3 in Saccharomyces cerevisiae and EttA in Escherichia coli have been found to function as ribosomal translation factors. Several other ABCFs including biochemically characterized VgaA, LsaA and MsrE confer resistance to antibiotics that target the peptidyl transferase center and exit tunnel of the ribosome. However, the diversity ...
DOI:: 10.1016/j.jmb.2018.12.013
PubMed:: 30597160
PubMed Central:: PMC6723617
: https://doi.org/10.1016/j.jmb.2018.12.013

39. Biodegradable Antimicrobial Food Packaging: Trends and Perspectives

Author:: Ludmila Motelica; Denisa Ficai; Anton Ficai; Ovidiu Cristian Oprea; Durmuş Alpaslan Kaya; Ecaterina Andronescu
Source:: Foods 2020 v.9 no.10 pp. -
ISSN:: 2304-8158
Subject:: active ingredients; agricultural resources; animals; antibiotics; antimicrobial packaging; antioxidant activity; bacteriocins; biodegradability; biopolymers; cellulose; chitosan; essential oils; evolution; extracts; food packaging; foods; industry; lipids; nanoparticles; packaging materials; plastics; pollution; polylactic acid; polyvinyl alcohol; public opinion; research; shelf life; solutions; starch; wastes
Abstract:: ... This review presents a perspective on the research trends and solutions from recent years in the domain of antimicrobial packaging materials. The antibacterial, antifungal, and antioxidant activities can be induced by the main polymer used for packaging or by addition of various components from natural agents (bacteriocins, essential oils, natural extracts, etc.) to synthetic agents, both organic ...
DOI:: 10.3390/foods9101438
: https://doi.org/10.3390/foods9101438

40. Comparing the selective and co-selective effects of different antimicrobials in bacterial communities

Author:: Aimee K. Murray; Lihong Zhang; Jason Snape; William H. Gaze
Source:: International journal of antimicrobial agents 2019 v.53 no.6 pp. 767-773
ISSN:: 0924-8579
Subject:: antibiotic resistance; antibiotic resistance genes; antibiotics; bacterial communities; benzalkonium chloride; ciprofloxacin; community structure; evolution; heavy metals; humans; metagenomics; quaternary ammonium compounds; resistance mechanisms; trimethoprim; wastewater
Abstract:: ... Bacterial communities are exposed to a cocktail of antimicrobial agents, including antibiotics, heavy metals and biocidal antimicrobials such as quaternary ammonium compounds (QACs). The extent to which these compounds may select or co-select for antimicrobial resistance (AMR) is not fully understood. In this study, human-associated, wastewater-derived bacterial communities were exposed to either ...
DOI:: 10.1016/j.ijantimicag.2019.03.001
PubMed:: 30885807
PubMed Central:: PMC6546120
: https://doi.org/10.1016/j.ijantimicag.2019.03.001

41. The Complexity of the Holobiont in the Red Sea Coral Euphyllia paradivisa under Heat Stress

Author:: Dalit Meron; Keren Maor-Landaw; Gal Eyal; Hila Elifantz; Ehud Banin; Yossi Loya; Oren Levy
Source:: Microorganisms 2020 v.8 no.3 pp. -
ISSN:: 2076-2607
Subject:: alpha-Proteobacteria; antibiotics; corals; evolution; gene expression regulation; gene ontology; heat stress; microorganisms; physiology; symbionts; temperature; transcriptomics; Red Sea
Abstract:: ... The recognition of the microbiota complexity and their role in the evolution of their host is leading to the popularization of the holobiont concept. However, the coral holobiont (host and its microbiota) is still enigmatic and unclear. Here, we explore the complex relations between different holobiont members of a mesophotic coral Euphyllia paradivisa. We subjected two lines of the coral&m ...
DOI:: 10.3390/microorganisms8030372
: https://doi.org/10.3390/microorganisms8030372

42. Culturing Ancient Bacteria Carrying Resistance Genes from Permafrost and Comparative Genomics with Modern Isolates

Author:: Pamela Afouda; Grégory Dubourg; Anthony Levasseur; Pierre-Edouard Fournier; Jeremy Delerce; Oleg Mediannikov; Seydina M. Diene; Daniel Nahon; Didier Bourlès; Jean-Marc Rolain; Didier Raoult
Source:: Microorganisms 2020 v.8 no.10 pp. -
ISSN:: 2076-2607
Subject:: Achromobacter; Brevundimonas aurantiaca; Gram-negative bacteria; Janibacter; Kocuria rhizophila; Microbacterium; antibiotic resistance; antibiotic resistance genes; antibiotics; biosphere; dynamics; evolution; genomics; humans; new species; permafrost; resistance mechanisms; sampling; single nucleotide polymorphism; strains; variability; viability
Abstract:: ... Long considered to be a consequence of human antibiotics use by deduction, antibiotic resistance mechanisms appear to be in fact a much older phenomenon as antibiotic resistance genes have previously been detected from millions of year-old permafrost samples. As these specimens guarantee the viability of archaic bacteria, we herein propose to apply the culturomics approach to recover the bacterial ...
DOI:: 10.3390/microorganisms8101522
: https://doi.org/10.3390/microorganisms8101522

43. Does Soil Contribute to the Human Gut Microbiome?

Author:: Winfried E.H. Blum; Sophie Zechmeister-Boltenstern; Katharina M. Keiblinger
Source:: Microorganisms 2019 v.7 no.9 pp. -
ISSN:: 2076-2607
Subject:: agrochemicals; antibiotics; beneficial microorganisms; digestive system; endophytes; epiphytes; evolution; feces; genes; humans; hygiene; intestinal microorganisms; lifestyle; low fiber diet; microbiome; processed foods; rural areas; soil; soil management; soil microorganisms; species diversity; urban areas; urbanization
Abstract:: ... Soil and the human gut contain approximately the same number of active microorganisms, while human gut microbiome diversity is only 10% that of soil biodiversity and has decreased dramatically with the modern lifestyle. We tracked relationships between the soil microbiome and the human intestinal microbiome. We propose a novel environmental microbiome hypothesis, which implies that a close linkage ...
DOI:: 10.3390/microorganisms7090287
PubMed:: 31450753
PubMed Central:: PMC6780873
: https://doi.org/10.3390/microorganisms7090287

44. Emerging evolutionary paradigms in antibiotic discovery

Author:: Marc G. Chevrette; Cameron R. Currie
Source:: Journal of industrial microbiology & biotechnology 2019 v.46 no.3-4 pp. 257-271
ISSN:: 1367-5435
Subject:: Actinobacteria; antibiotics; biochemical pathways; ecology; evolution; microorganisms; pathogens; secondary metabolites; toxicity
Abstract:: ... Antibiotics revolutionized medicine and remain its cornerstone. Despite their global importance and the continuous threat of resistant pathogens, few antibiotics have been discovered in recent years. Natural products, especially the secondary metabolites of Actinobacteria, have been the traditional discovery source of antibiotics. In nature, the chemistry of antibiotic natural products is shaped b ...
DOI:: 10.1007/s10295-018-2085-6
: https://doi.org/10.1007/s10295-018-2085-6

45. Genetic parameters of resistance to pasteurellosis using novel response traits in rabbits

Author:: Merina Shrestha; Hervé Garreau; Elodie Balmisse; Bertrand Bed’hom; Ingrid David; Edouard Guitton; Emmanuelle Helloin; Guillaume Lenoir; Mickaël Maupin; Raphaël Robert; Frédéric Lantier; Mélanie Gunia
Source:: Genetics, selection, evolution 2020 v.52 no.1 pp. 34
ISSN:: 1297-9686
Subject:: Pasteurella multocida; abscess; antibiotics; average daily gain; bacteria; breeding programs; commercial farms; crossbreds; evolution; experimental design; genetic correlation; genetic resistance; genetic variation; heritability; laboratories; necropsy; pasteurellosis; phenotypic correlation; population; prevalence; rabbits; selection criteria; sires; weaning weight
Abstract:: ... BACKGROUND: Pasteurellosis (Pasteurella infection) is one of the most common bacterial infections in rabbits on commercial farms and in laboratory facilities. Curative treatments using antibiotics are only partly efficient, with frequent relapses. Breeding rabbits for improved genetic resistance to pasteurellosis is a sustainable alternative approach. In this study, we infected 964 crossbred rabbi ...
DOI:: 10.1186/s12711-020-00552-8
: https://doi.org/10.1186/s12711-020-00552-8

46. Horizontal transfer of antibiotic resistance genes in clinical environments

Author:: Nicole A. Lerminiaux; Andrew D.S. Cameron
Source:: Canadian journal of microbiology 2019 v.65 no.1 pp. 34-44
ISSN:: 1480-3275
Subject:: antibiotic resistance; antibiotic resistance genes; antibiotics; bacteriophages; diagnostic techniques; evolution; horizontal gene transfer; hospitals; infectious diseases; inheritance (genetics); pathogens; plasmids
Abstract:: ... A global medical crisis is unfolding as antibiotics lose effectiveness against a growing number of bacterial pathogens. Horizontal gene transfer (HGT) contributes significantly to the rapid spread of resistance, yet the transmission dynamics of genes that confer antibiotic resistance are poorly understood. Multiple mechanisms of HGT liberate genes from normal vertical inheritance. Conjugation by p ...
DOI:: 10.1139/cjm-2018-0275
: https://doi.org/10.1139/cjm-2018-0275

47. Local applications but global implications: Can pesticides drive microorganisms to develop antimicrobial resistance?

Author:: Balasubramanian Ramakrishnan; Kadiyala Venkateswarlu; Nambrattil Sethunathan; Mallavarapu Megharaj
Source:: Science of the total environment 2019 v.654 pp. 177-189
ISSN:: 0048-9697
Subject:: active ingredients; air; antibiotic resistance; antibiotics; chemotaxis; chromosomes; enzymes; evolution; genes; inheritance (genetics); leaves; microbiome; microorganisms; pesticide degradation; pesticides; physiological transport; plant tissues; plasmids; soil pollution; transporters
Abstract:: ... Pesticides are an important agricultural input, and the introduction of new active ingredients with increased efficiencies drives their higher production and consumption worldwide. Inappropriate application and storage of these chemicals often contaminate plant tissues, air, water, or soil environments. The presence of pesticides can lead to developing tolerance, resistance or persistence and even ...
DOI:: 10.1016/j.scitotenv.2018.11.041
: https://doi.org/10.1016/j.scitotenv.2018.11.041

48. Medical leech therapy in Ayurveda and biomedicine – A review

Author:: Sarvesh Kumar Singh; Kshipra Rajoria
Source:: Journal of Ayurveda and integrative medicine 2020 v.11 no.4 pp. 554-564
ISSN:: 0975-9476
Subject:: Ayurvedic medicine; antibiotics; evolution; flow; knowledge; paper; research; roots; surgery
Abstract:: ... Medicinal leech therapy or Hirudino therapy have roots back in ancient civilization. It was a prevalent form of therapy in various ailments. The novel Ayurveda text Sushruta Samhita devoted a complete chapter on hirudino therapy. In the early 20th century this therapy had a major setback due to origin and evolution of antibiotics. There was a discontinuity in the flow of knowledge about this thera ...
DOI:: 10.1016/j.jaim.2018.09.003
: https://doi.org/10.1016/j.jaim.2018.09.003

49. Spatial distribution of antibiotic and heavy metal resistance genes in the Black Sea

Author:: Raffaella Sabatino; Andrea Di Cesare; Nina Dzhembekova; Diego Fontaneto; Ester M. Eckert; Gianluca Corno; Snejana Moncheva; Roberto Bertoni; Cristiana Callieri
Source:: Marine pollution bulletin 2020 v.160 pp. 111635
ISSN:: 0025-326X
Subject:: antibiotic resistance; antibiotics; basins; evolution; human health; marine pollution; metal tolerance; shorelines; Black Sea
Abstract:: ... Antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB) are worldwide considered as emerging contaminants of large interest, and a primary threat to human health. It is becoming clear that the environment plays a central role in the transmission, spread, and evolution of antibiotic resistance. Although marine systems have been largely investigated, only a few studies have consid ...
DOI:: 10.1016/j.marpolbul.2020.111635
: https://doi.org/10.1016/j.marpolbul.2020.111635

50. Therapeutic lipid-coated hybrid nanoparticles against bacterial infections

Author:: Lai Jiang; Hiang Wee Lee; Say Chye Joachim Loo
Source:: RSC advances 2020 v.10 no.14 pp. 8497-8517
ISSN:: 2046-2069
Subject:: antibiotics; biofilm; cross infection; evolution; lipids; therapeutics
Abstract:: ... One of the most important health concerns in society is the development of pathogen-causing nosocomial infections. Since the first discovery of antibiotics, bacterial infections have been highly treatable. However, with evolution and the nondiscretionary usage of antibiotics, pathogens have also found new ways to survive the onslaught of antibiotics by surviving intracellularly or through the form ...
DOI:: 10.1039/c9ra10921h
: https://doi.org/10.1039/c9ra10921h

51. Tildipirosin: An effective antibiotic against Glaesserella parasuis from an in vitro analysis

Author:: Priscila Rodrigues Peres; Simone Ramos Prigol; César Bernardo Gutiérrez Martín; César Feronatod; Miquel Collell Suriñach; Luiz Carlos Kreutz; Rafael Frandoloso
Source:: Veterinary and Animal Science 2020 v.10 pp. 100136
ISSN:: 2451-943X
Subject:: Actinobacillus pleuropneumoniae; Gram-negative bacteria; animal science; antibiotics; assays; disease outbreaks; etiological agents; evolution; infection; information; macrolides; minimum inhibitory concentration; swine; therapeutics
Abstract:: ... Tildipirosin is a latest generation macrolide that is used to battle infection diseases caused by Gram-negative bacteria. Recent studies have shown the effectiveness of this antimicrobial agent against Actinobacillus pleuropneumoniae; however, little information is available about Glaesserella parasuis, the etiological agent of Glässer's disease. In this study, the Tildipirosin activity to 100 Bra ...
DOI:: 10.1016/j.vas.2020.100136
: https://doi.org/10.1016/j.vas.2020.100136

52. Toward a chimeric vaccine against multiple isolates of Mycobacteroides - An integrative approach

Author:: Rohit Satyam; Tulika Bhardwaj; Niraj Kumar Jha; Saurabh Kumar Jha; Parma Nand
Source:: Life sciences 2020 v.250 pp. 117541
ISSN:: 0024-3205
Subject:: B-lymphocytes; Toll-like receptor 4; adjuvants; allergenicity; antibiotics; bacteria; drug resistance; epitopes; evolution; genomics; major histocompatibility complex; medicine; molecular dynamics; mycobacterial diseases; proteome; proteomics; recombinant vaccines; signal peptide; virulence
Abstract:: ... Nontuberculous mycobacterial (NTM) infection such as endophthalmitis, dacryocystitis, and canaliculitis are pervasive across the globe and are currently managed by antibiotics. However, the recent cases of Mycobacteroides developing drug resistance reported along with the improper practice of medicine intrigued us to explore its genomic and proteomic canvas at a global scale and develop a chimeric ...
DOI:: 10.1016/j.lfs.2020.117541
: https://doi.org/10.1016/j.lfs.2020.117541

53. The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds

Author:: L. Montoro-Dasi; A. Villagra; S. Sevilla-Navarro; M.T. Pérez-Gracia; S. Vega; C. Marin
Source:: Poultry science 2020 v.99 no.3 pp. 1591-1597
ISSN:: 0032-5791
Subject:: Escherichia coli; animal welfare; antibiotic resistance; antibiotics; bacteria; epidemiology; evolution; public health; slaughter
Abstract:: ... Antimicrobial resistance (AMR) is an important threat to public health worldwide. Furthermore, different studies have demonstrated a close association between antibiotic use in animal production and AMR in humans. It is well known that it is necessary to reduce antibiotic administration in farms by finding effective alternative treatments, using more resistant breeds and improving animal welfare. ...
DOI:: 10.1016/j.psj.2019.10.080
: https://doi.org/10.1016/j.psj.2019.10.080

54. The impact and mechanism of quaternary ammonium compounds on the transmission of antibiotic resistance genes

Author:: Yue Han; Zhen-Chao Zhou; Lin Zhu; Yuan-Yuan Wei; Wan-Qiu Feng; Lan Xu; Yang Liu; Ze-Jun Lin; Xin-Yi Shuai; Zhi-Jian Zhang; Hong Chen
Source:: Environmental science and pollution research international 2019 v.26 no.27 pp. 28352-28360
ISSN:: 0944-1344
Subject:: antibiotic resistance; antibiotic resistance genes; antibiotics; bacteria; biocides; cell membranes; detergents; disinfectants; evolution; flow cytometry; gene transfer; genetic conjugation; membrane permeability; microbiome; plasmids; quantitative polymerase chain reaction; quaternary ammonium compounds; reactive oxygen species; watersheds
Abstract:: ... The emergence of antibiotic resistance genes (ARGs) in microbes can be largely attributed to the abuse and misuse of antibiotics and biocides. Quaternary ammonium compounds (QACs) have been used worldwide as common disinfectants and detergents; however, their potential impact on the spread and diffusion of ARGs is still unknown. In this study, we detected the QAC resistance gene (qacEΔ1), the 1 in ...
DOI:: 10.1007/s11356-019-05673-2
: https://doi.org/10.1007/s11356-019-05673-2

55. Application of biosolids drives the diversity of antibiotic resistance genes in soil and lettuce at harvest

Author:: Lu Yang; Wuxing Liu; Dong Zhu; Jinyu Hou; Tingting Ma; Longhua Wu; Yongguan Zhu; Peter Christie
Source:: Soil biology & biochemistry 2018 v.122 pp. 131-140
ISSN:: 0038-0717
Subject:: antibiotic resistance genes; antibiotics; biosolids; endophytes; evolution; leaves; lettuce; quantitative polymerase chain reaction; ready-to-eat foods; roots; shoots; soil
Abstract:: ... High-throughput quantitative polymerase chain reaction (PCR) of antibiotic resistance genes (ARGs) was used to profile the composition and diversity of ARGs in biosolid-amended soil and in lettuce roots and shoots. Biosolid application significantly increased the ARGs in soil and influenced the soil antibiotics resistome mainly through exogenous introduction. Four dominant ARGs occurred in sterili ...
DOI:: 10.1016/j.soilbio.2018.04.017
: https://doi.org/10.1016/j.soilbio.2018.04.017

56. Characterization and genome analysis of the temperate bacteriophage φSAJS1 from Streptomyces avermitilis

Author:: Nana Lu; Choljin Kim; Zhi Chen; Ying Wen; Qing Wei; Yi Qiu; Shiwei Wang; Yuan Song
Source:: Virus research 2019 v.265 pp. 34-42
ISSN:: 0168-1702
Subject:: DNA; DNA packaging; Siphoviridae; Streptomyces avermitilis; Streptomyces griseus; antibiotics; bacteria; bacteriophages; calcium; evolution; fermentation; genome; growth curves; host range; open reading frames; pH; proteins; sequence analysis; temperature; transmission electron microscopy
Abstract:: ... Streptomyces is an important antibiotic-producing bacterium; however, antibiotic production is often negatively affected by bacteriophage contamination. In the present study, the temperate phage φSAJS1 was isolated and characterized from an unsuccessful Streptomyces avermitilis fermentation culture. The complete genome of phage φSAJS1 was sequenced. Phage φSAJS1 belongs to the Siphoviridae family ...
DOI:: 10.1016/j.virusres.2019.03.006
: https://doi.org/10.1016/j.virusres.2019.03.006

57. Comparative proteomics analyses of Acinetobacter baumannii strains ATCC 17978 and AB5075 reveal the differential role of type II secretion system secretomes in lung colonization and ciprofloxacin resistance

Author:: Noha M. Elhosseiny; Nada B. Elhezawy; Ahmed S. Attia
Source:: Microbial pathogenesis 2019 v.128 pp. 20-27
ISSN:: 0882-4010
Subject:: Acinetobacter baumannii; antibiotic resistance; antibiotics; biofilm; ciprofloxacin; cross infection; enzymes; evolution; gentian violet; lungs; mice; minimum inhibitory concentration; models; pathogens; pneumonia; proteomics; resistance mechanisms; transposons; type II secretion system; virulence; virulent strains
Abstract:: ... Acinetobacter baumannii is an emerging nosocomial pathogen with alarming antibiotic resistance profiles. A better understanding of the virulence and resistance mechanisms of this pathogen is necessary for identifying new methods to combat its infections in a more efficient way. In this regard, the type II secretion system (T2SS) of A. baumannii is an attractive target majorly secreting lipid-metab ...
DOI:: 10.1016/j.micpath.2018.12.039
: https://doi.org/10.1016/j.micpath.2018.12.039

58. Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance

Author:: D.G. Joakim Larsson; Antoine Andremont; Johan Bengtsson-Palme; Kristian Koefoed Brandt; Ana Maria de Roda Husman; Patriq Fagerstedt; Jerker Fick; Carl-Fredrik Flach; William H. Gaze; Makoto Kuroda; Kristian Kvint; Ramanan Laxminarayan; Celia M. Manaia; Kaare Magne Nielsen; Laura Plant; Marie-Cécile Ploy; Carlos Segovia; Pascal Simonet; Kornelia Smalla; Jason Snape; Edward Topp; Arjon J. van Hengel; David W. Verner-Jeffreys; Marko P.J. Virta; Elizabeth M. Wellington; Ann-Sofie Wernersson
Source:: Environment international 2018 v.117 pp. 132-138
ISSN:: 0160-4120
Subject:: Internet; animal and human health; antibiotic resistance; antibiotics; bacteria; evolution; experts; pathogens; risk; scientists; stakeholders
Abstract:: ... There is growing understanding that the environment plays an important role both in the transmission of antibiotic resistant pathogens and in their evolution. Accordingly, researchers and stakeholders world-wide seek to further explore the mechanisms and drivers involved, quantify risks and identify suitable interventions. There is a clear value in establishing research needs and coordinating effo ...
DOI:: 10.1016/j.envint.2018.04.041
: https://doi.org/10.1016/j.envint.2018.04.041

59. Detection of Extended-Spectrum β-Lactamase-Producing Escherichia coli Using Infrared Microscopy and Machine-Learning Algorithms

Author:: Uraib Sharaha; Eladio Rodriguez-Diaz; Orli Sagi; Klaris Riesenberg; Itshak Lapidot; Yoram Segal; Irving J. Bigio; Mahmoud Huleihel; Ahmad Salman
Source:: Analytical chemistry 2019 v.91 no.3 pp. 2525-2530
ISSN:: 1520-6882
Subject:: algorithms; antibiotics; beta-lactamase bacteria; evolution; microscopy; mortality; multiple drug resistance; multivariate analysis; patients; rapid methods; spectroscopy; urinary tract; urinary tract diseases; urine; uropathogenic Escherichia coli
Abstract:: ... The spread of multidrug resistant bacteria has become a global concern. One of the most important and emergent classes of multidrug-resistant bacteria is extended-spectrum β-lactamase-producing bacteria (ESBL-positive = ESBL⁺). Due to widespread and continuous evolution of ESBL-producing bacteria, they become increasingly resistant to many of the commonly used antibiotics, leading to an increase i ...
DOI:: 10.1021/acs.analchem.8b05497
: https://doi.org/10.1021/acs.analchem.8b05497

60. Distribution of antibiotic resistance and virulence factors among the bacteria isolated from diseased Etroplus suratensis

Author:: Aswani Ravi; Soumya Das; Jasim Basheer; Aswathy Chandran; Chinnu Benny; Sindhura Somaraj; Sebastian Korattiparambil Sebastian; Jyothis Mathew; Radhakrishnan Edayileveettil Krishnankutty
Source:: 3 Biotech 2019 v.9 no.4 pp. 138
ISSN:: 2190-572X
Subject:: Etroplus suratensis; antibiotic resistance; antibiotics; bacteria; deoxyribonucleases; evolution; fish; genes; hemolysins; hemolysis; monitoring; polymerase chain reaction; screening; virulence
Abstract:: ... Considering the emerging concern with the antimicrobial resistance (AMR) evolution, the study has been designed to identify the antibiotic resistance and virulence properties of culturable bacteria isolated from the diseased fish Etroplus suratensis. This has resulted in the purification of 18 morphologically distinct bacterial isolates which were identified by both biochemical and molecular metho ...
DOI:: 10.1007/s13205-019-1654-3
PubMed:: 30944785
PubMed Central:: PMC6419682
: https://doi.org/10.1007/s13205-019-1654-3

61. Evolution of structural fitness and multifunctional aspects of mycobacterial RND family transporters

Author:: Padmani Sandhu; Yusuf Akhter
Source:: Archives of microbiology 2018 v.200 no.1 pp. 19-31
ISSN:: 0302-8933
Subject:: Mycobacterium tuberculosis; antibiotics; bacteria; drugs; evolution; multiple drug resistance; nodulation; pathogens; transporters
Abstract:: ... Drug resistance is a major concern due to the evolution and emergence of pathogenic bacterial strains with novel strategies to resist the antibiotics in use. Mycobacterium tuberculosis (Mtb) is one of such pathogens with reported strains, which are not treatable with any of the available anti-TB drugs. This scenario has led to the need to look for some novel drug targets in Mtb, which may be explo ...
DOI:: 10.1007/s00203-017-1434-6
: https://doi.org/10.1007/s00203-017-1434-6

62. Inhibiting the Evolution of Antibiotic Resistance

Author:: Mark N. Ragheb; Maureen K. Thomason; Chris Hsu; Patrick Nugent; John Gage; Ariana N. Samadpour; Ankunda Kariisa; Christopher N. Merrikh; Samuel I. Miller; David R. Sherman; Houra Merrikh
Source:: Molecular cell 2019 v.73 no.1 pp. 157-165.e5
ISSN:: 1097-2765
Subject:: DNA; DNA repair; DNA-directed RNA polymerase; alleles; antibiotic resistance; antibiotics; evolution; mutagenesis; new drugs; trimethoprim
Abstract:: ... Efforts to battle antimicrobial resistance (AMR) are generally focused on developing novel antibiotics. However, history shows that resistance arises regardless of the nature or potency of new drugs. Here, we propose and provide evidence for an alternate strategy to resolve this problem: inhibiting evolution. We determined that the DNA translocase Mfd is an “evolvability factor” that promotes muta ...
DOI:: 10.1016/j.molcel.2018.10.015
PubMed:: 30449724
PubMed Central:: PMC6320318
: https://doi.org/10.1016/j.molcel.2018.10.015

63. New Selectable Markers for Volvox carteri Transformation

Author:: José A. Ortega-Escalante; Owen Kwok; Stephen M. Miller
Source:: Protist 2019 v.170 no.1 pp. 52-63
ISSN:: 1434-4610
Subject:: Bacillus cereus; Coccidioides posadasii; Volvox; antibiotic resistance; antibiotics; biolistics; cell differentiation; evolution; genetic analysis; messenger RNA; models; nitrate reductase; plasmids; regulatory sequences; resistance genes; transgenes
Abstract:: ... Volvox carteri is an excellent model for investigating the evolution of multicellularity and cell differentiation, and the rate of future progress with this system will depend on improved molecular genetic tools. Several selectable markers for nuclear transformation of V. carteri have been developed, including the nitrate reductase (nitA) gene, but it would be useful to have additional markers to ...
DOI:: 10.1016/j.protis.2018.11.002
: https://doi.org/10.1016/j.protis.2018.11.002

64. Silver nanoparticles as antimicrobial therapeutics: current perspectives and future challenges

Author:: Parteek Prasher; Manjeet Singh; Harish Mudila
Source:: 3 Biotech 2018 v.8 no.10 pp. 411
ISSN:: 2190-572X
Subject:: antibiotics; control methods; drug therapy; drugs; evolution; multiple drug resistance; nanosilver; silver; synergism
Abstract:: ... Utility of silver metal in antimicrobial therapy is an accepted practice since ages that faded with time because of the identification of a few silver resistant strains in the contemporary era. A successive development of antibiotics soon followed. However, due to an indiscriminate and unregulated use coupled with poor legal control measures and a dearth of expertise in handling the critical episo ...
DOI:: 10.1007/s13205-018-1436-3
PubMed:: 30237958
PubMed Central:: PMC6138003
: https://doi.org/10.1007/s13205-018-1436-3

65. The scent of symbiosis: gut bacteria may affect social interactions in leaf-cutting ants

Author:: Serafino Teseo; Jelle S. van Zweden; Luigi Pontieri; Pepijn W. Kooij; Søren J. Sørensen; Tom Wenseleers; Michael Poulsen; Jacobus J. Boomsma; Panagiotis Sapountzis
Source:: Animal behaviour 2019 v.150 pp. 239-254
ISSN:: 0003-3472
Subject:: Acromyrmex echinatior; aggression; animals; antibiotics; antifungal agents; bacterial communities; chemical analysis; diet; droplets; evolution; hosts; intestinal microorganisms; leaf-cutting ants; microsymbionts; nestmate recognition; odors; physiology; social behavior; symbiosis
Abstract:: ... Animal gut microbiota affect host physiology and behaviour. In social insects, where colony level integrity is preserved via a nestmate discrimination system based on cuticular hydrocarbon mixtures, microorganismal effects may therefore influence social dynamics. Although nestmate recognition has undergone a thorough exploration during the last four decades, few studies have investigated the putat ...
DOI:: 10.1016/j.anbehav.2018.12.017
: https://doi.org/10.1016/j.anbehav.2018.12.017

66. Staphylococcus aureus Sequences from Osteomyelitic Specimens of a Pathological Bone Collection from Pre-Antibiotic Times

Author:: Anna Lena Flux; Janine Mazanec; Birgit Strommenger; Susanne Hummel
Source:: Diversity 2017 v.9 no.4 pp. -
ISSN:: 1424-2818
Subject:: DNA; antibiotics; evolution; genes; methicillin-resistant Staphylococcus aureus; microorganisms; necropsy; nucleotide sequences; osteomyelitis; pathogens; polymerase chain reaction; public health
Abstract:: ... Staphylococcus aureus is a major pathogen causing osteomyelitis, amongst other diseases, and its methicillin-resistant form (MRSA) in particular poses a huge threat to public health. To increase our knowledge of the origin and evolution of S. aureus, genetic studies of historical microorganisms may be beneficial. Thus, the aim of this study was to investigate whether osteomyelitic skeletal materia ...
DOI:: 10.3390/d9040043
: https://doi.org/10.3390/d9040043

67. Comparative genome analysis of IncHI2 VIM-1 carbapenemase-encoding plasmids of Escherichia coli and Salmonella enterica isolated from a livestock farm in Germany

Author:: Linda Falgenhauer; Hiren Ghosh; Beatriz Guerra; Yancheng Yao; Moritz Fritzenwanker; Jennie Fischer; Reiner Helmuth; Can Imirzalioglu; Trinad Chakraborty
Source:: Veterinary microbiology 2017 v.200 pp. 114-117
ISSN:: 0378-1135
Subject:: Escherichia coli; Salmonella enterica; antibiotics; beta-lactamase; evolution; genes; heavy metals; humans; livestock; livestock and meat industry; plasmids; sequence analysis; Germany
Abstract:: ... Carbapenem-resistant Enterobacteriaceae are not any more isolated only from human settings, but also from livestock. We reported for the first time the presence of VIM-1 carbapenemases in a livestock farm in Germany. The VIM-1 resistance gene found in these farms was located on IncHI2 plasmids. In order to be able to analyse these plasmids in more detail, two different plasmids from a single farm ...
DOI:: 10.1016/j.vetmic.2015.09.001
: https://doi.org/10.1016/j.vetmic.2015.09.001

68. Confronting herbicide resistance with cooperative management

Author:: Jeffrey A Evans; Alwyn Williams; Aaron G Hager; Steven B Mirsky; Patrick J Tranel; Adam S Davis
Source:: Pest management science 2018 v.74 no.11 pp. 2424-2431
ISSN:: 1526-498X
Subject:: Amaranthus tuberculatus; antibiotics; collaborative management; evolution; farms; glyphosate; glyphosate resistance; herbicide-resistant weeds; models; pathogens
Abstract:: ... BACKGROUND: Resistance of pathogens and pests to antibiotics and pesticides worldwide is rapidly reaching critical levels. The common‐pool‐resource nature of this problem (i.e. whereby the susceptibility to treatment of target organisms is a shared resource) has been largely overlooked. Using herbicide‐resistant weeds as a model system, we developed a discrete‐time landscape‐scale simulation to in ...
DOI:: 10.1002/ps.5105
PubMed:: 29862629
PubMed Central:: PMC6220798
CHORUS:: 10.1002/ps.5105
Chorus Open Access:: 10.1002/ps.5105
: https://doi.org/10.1002/ps.5105

69. Evolutionary Mechanisms Shaping the Maintenance of Antibiotic Resistance

Author:: Paulo Durão; Roberto Balbontín; Isabel Gordo
Source:: Trends in microbiology 2018 v.26 no.8 pp. 677-691
ISSN:: 0966-842X
Subject:: antibiotic resistance; antibiotics; bacteria; drugs; epistasis; evolution; mutation; resistance genes
Abstract:: ... Antibiotics target essential cellular functions but bacteria can become resistant by acquiring either exogenous resistance genes or chromosomal mutations. Resistance mutations typically occur in genes encoding essential functions; these mutations are therefore generally detrimental in the absence of drugs. However, bacteria can reduce this handicap by acquiring additional mutations, known as compe ...
DOI:: 10.1016/j.tim.2018.01.005
: https://doi.org/10.1016/j.tim.2018.01.005

70. Plasmid and clonal interference during post horizontal gene transfer evolution

Author:: S. Bedhomme; D. Perez Pantoja; I. G. Bravo
Source:: Molecular ecology 2017 v.26 no.7 pp. 1832-1847
ISSN:: 0962-1083
Subject:: antibiotic resistance; antibiotics; clones; evolution; gene expression; genes; genetic resistance; high-throughput nucleotide sequencing; horizontal gene transfer; parasites; plasmids; public health; toxins
Abstract:: ... Plasmids are nucleic acid molecules that can drive their own replication in a living cell. They can be transmitted horizontally and can thrive in the host cell to high‐copy numbers. Plasmid replication and gene expression consume cellular resources and cells carrying plasmids incur fitness costs. But many plasmids carry genes that can be beneficial under certain conditions, allowing the cell to en ...
DOI:: 10.1111/mec.14056
PubMed:: 28206693
PubMed Central:: PMC5392415
: https://doi.org/10.1111/mec.14056

71. Population structure of Pseudomonas aeruginosa through a MLST approach and antibiotic resistance profiling of a Mexican clinical collection

Author:: F.J. Castañeda-Montes; M. Avitia; O. Sepúlveda-Robles; V. Cruz-Sánchez; L. Kameyama; G. Guarneros; A.E. Escalante
Source:: Infection, genetics, and evolution 2018 v.65 pp. 43-54
ISSN:: 1567-1348
Subject:: Pseudomonas aeruginosa; antibiotic resistance; antibiotics; cross infection; developed countries; developing countries; education; environmental factors; epidemiological studies; evolution; health care workers; health services; infrastructure; medical treatment; microbiology; pathogens; population dynamics; population genetics; population structure; poverty; public policy; Mexico
Abstract:: ... Pseudomonas aeruginosa is one of the most important pathogens worldwide. Population genetics studies have shown that the P. aeruginosa population has an epidemic structure with highly conserved clonal complexes. Nonetheless, epidemiological studies of P. aeruginosa have been historically absent or infrequent in developing countries, in which different medical treatments, conditions and infrastruct ...
DOI:: 10.1016/j.meegid.2018.06.009
: https://doi.org/10.1016/j.meegid.2018.06.009

72. Role of Aromatic and Negatively Charged Residues of DrrB in Multisubstrate Specificity Conferred by the DrrAB System of Streptomyces peucetius

Author:: Brown Kenneth; Li Wen; Kaur Parjit
Source:: Biochemistry 2017 v.56 no.13 pp. 1921-1931
ISSN:: 1520-4995
Subject:: P-glycoproteins; Streptomyces peucetius; antibiotics; doxorubicin; ethidium; evolution; models; multiple drug resistance; mutants; mutation; substrate specificity; verapamil
Abstract:: ... Resistance to the anticancer antibiotics, doxorubicin and daunorubicin, in the producer organism Streptomyces peucetius is conferred by an ABC transporter made of two proteins, DrrA and DrrB, which together form a dedicated exporter for these two antibiotics. Surprisingly, however, the DrrAB system exhibits broad substrate specificity overlapping with well-studied multidrug resistance transporters ...
DOI:: 10.1021/acs.biochem.6b01155
: https://doi.org/10.1021/acs.biochem.6b01155

73. Tiamulin removal by wood-rot fungi isolated from swine farms and role of ligninolytic enzymes

Author:: Thi Kim Xuan Nguyen; Parinda Thayanukul; Onruthai Pinyakong; Oramas Suttinun
Source:: International biodeterioration & biodegradation 2017 v.116 pp. 147-154
ISSN:: 0964-8305
Subject:: Coriolus hirsutus; Coriolus versicolor; Fusarium; Galactomyces; Lasiodiplodia; Verticillium; antibiotics; composting; composts; decay fungi; decolorization; evolution; farms; genes; gentian violet; livestock and meat industry; manganese peroxidase; manure storage; pig manure; risk; swine; tiamulin
Abstract:: ... Tiamulin (TIA) is a widely used antibiotic in Thai swine farms and persists in swine manure storage. Significant amounts remain in swine manure after composting, posing risks related to the spread of the compound and the evolution of resistant genes when this compost is used as a fertilizer. Therefore, it is necessary to enhance TIA degradation. This study successfully purified TIA-degrading fungi ...
DOI:: 10.1016/j.ibiod.2016.10.010
: https://doi.org/10.1016/j.ibiod.2016.10.010

74. A cytometric approach to follow variation and dynamics of the salivary microbiota

Author:: Susanna van Gelder; Nicola Röhrig; Florian Schattenberg; Nicolas Cichocki; Joachim Schumann; Gerhard Schmalz; Rainer Haak; Dirk Ziebolz; Susann Müller
Source:: Methods 2017 pp. -
ISSN:: 1046-2023
Subject:: Fusobacteria; sugars; community structure; antibiotics; Proteobacteria; bacteria; evolution; monitoring; saliva; flow cytometry; microbiome; Firmicutes; ecosystems; Actinobacteria; information processing; Bacteroidetes
Abstract:: ... Microbial flow cytometry is an established fast and economic technique for complex ecosystem studies and enables visualization of rapidly changing community structures by measuring characteristics of single microbial cells. Cytometric evaluation routines are available such as flowCyBar which are useful for automatic data processing. Here, a cytometric workflow was established which allows to routi ...
DOI:: 10.1016/j.ymeth.2017.08.009
: https://doi.org/10.1016/j.ymeth.2017.08.009

75. Bioinformatics tools and databases for whole genome sequence analysis of Mycobacterium tuberculosis

Author:: Kiatichai Faksri; Jun Hao Tan; Angkana Chaiprasert; Yik-Ying Teo; Rick Twee-Hee Ong
Source:: Infection, genetics, and evolution 2016 v.45 pp. 359-368
ISSN:: 1567-1348
Subject:: Mycobacterium tuberculosis; antibiotic resistance; antibiotics; bacteria; bioinformatics; computer software; cost effectiveness; disease transmission; evolution; genetic databases; genetic variation; genomics; high-throughput nucleotide sequencing; molecular epidemiology; nucleotide sequences; patients; public health; surveys; tuberculosis
Abstract:: ... Tuberculosis (TB) is an infectious disease of global public health importance caused by Mycobacterium tuberculosis complex (MTC) in which M. tuberculosis (Mtb) is the major causative agent. Recent advancements in genomic technologies such as next generation sequencing have enabled high throughput cost-effective generation of whole genome sequence information from Mtb clinical isolates, providing n ...
DOI:: 10.1016/j.meegid.2016.09.013
: https://doi.org/10.1016/j.meegid.2016.09.013

76. Metagenomic Analysis Revealing Antibiotic Resistance Genes (ARGs) and Their Genetic Compartments in the Tibetan Environment

Author:: Chen Baowei; Yuan Ke; Chen Xin; Yang Ying; Zhang Tong; Wang Yawei; Luan Tiangang; Zou Shichun; Li Xiangdong
Source:: Environmental Science & Technology 2016 v.50 no.13 pp. 6670-6679
ISSN:: 1520-5851
Subject:: animal wastes; antibiotic resistance; antibiotics; bacteria; bacterial communities; beta-lactams; chemical analysis; community structure; evolution; fluoroquinolones; genes; interspersed repetitive sequences; metagenomics; sediments; soil; China
Abstract:: ... Comprehensive profiles of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in a minimally impacted environment are essential to understanding the evolution and dissemination of modern antibiotic resistance. Chemical analyses of the samples collected from Tibet demonstrated that the region under investigation was almost devoid of anthropogenic antibiotics. The soils, animal was ...
DOI:: 10.1021/acs.est.6b00619
: https://doi.org/10.1021/acs.est.6b00619

77. Probing minority population of antibiotic-resistant bacteria

Author:: Tianxun Huang; Yan Zheng; Ya Yan; Lingling Yang; Yihui Yao; Jiaxin Zheng; Lina Wu; Xu Wang; Yuqing Chen; Jinchun Xing; Xiaomei Yan
Source:: Biosensors & bioelectronics 2016 v.80 pp. 323-330
ISSN:: 0956-5663
Subject:: Escherichia coli; antibiotic resistance; antibiotics; bacteria; beta-lactamase; biosensors; evolution; flow cytometry; fluorescence; fluorescent dyes; microbial culture; microbial load; monitoring; monoclonal antibodies; nucleic acids; pathogens; public health; quantitative analysis; urine
Abstract:: ... The evolution and spread of antibiotic-resistant pathogens has become a major threat to public health. Advanced tools are urgently needed to quickly diagnose antibiotic-resistant infections to initiate appropriate treatment. Here we report the development of a highly sensitive flow cytometric method to probe minority population of antibiotic-resistant bacteria via single cell detection. Monoclonal ...
DOI:: 10.1016/j.bios.2016.01.054
: https://doi.org/10.1016/j.bios.2016.01.054

78. Pteridophytes: evolutionary boon as medicinal plants

Author:: Hit Kishore Goswami; Kakali Sen; Radhanath Mukhopadhyay
Source:: Plant genetic resources 2016 v.14 no.4 pp. 328-355
ISSN:: 1479-263X
Subject:: Athyrium niponicum; Azolla; Bryophyta; Ceratopteris; Cyrtomium; DNA; Davallia; Dicranopteris; Dryopteris; Equisetum hyemale; Gram-positive bacteria; Lycopodium; Marsilea; Microsorum; Mycobacterium phlei; Oriental traditional medicine; Paleozoic era; Polypodium; Polystichum; Pseudomonas aeruginosa; Pyrrosia; Salmonella Typhi; Salvinia; Staphylococcus aureus; Vibrio cholerae; active ingredients; alkaloids; amino acids; antibacterial properties; antibiotics; antioxidant activity; antioxidants; antiretroviral agents; biodiversity; biofertilizers; bioremediation; evolution; fatty acids; ferns and fern allies; flavonoids; flora; forest reserves; forests; freshwater; fronds; fungi; gene regulatory networks; genes; genomics; herbal medicines; human health; lakes; lichens; mammals; medicinal plants; neoplasms; oils; pharmaceutical industry; plant extracts; polyphenols; polysaccharides; reptiles; rhizomes; screening; secondary metabolites; steroids; surface water; tea; triterpenoids; vascular plants; weeds
Abstract:: ... Selective use of crude plant extracts has been the oldest ritual in ancient Indian Medicinal System ‘Ayurveda’, as well as in Traditional Chinese Medicine system for thousands of years. This has been well documented that herbal medicines of Chinese, Indian, Korean and Native American people had included bryophytes, lichens, lycophytes and ferns. Since antiquity, most of the ferns and fern allies h ...
DOI:: 10.1017/S1479262116000290
: https://doi.org/10.1017/S1479262116000290

79. Regulation of conjugative transfer of plasmids and integrative conjugative elements

Author:: Luis Alfredo Bañuelos-Vazquez; Gonzalo Torres Tejerizo; Susana Brom
Source:: Plasmid 2017 v.91 pp. 82-89
ISSN:: 0147-619X
Subject:: antibiotics; chromosomes; evolution; genes; horizontal gene transfer; metal tolerance; pathogenesis; plasmids; quorum sensing; regulatory sequences; symbiosis
Abstract:: ... Horizontal gene transfer has been recognized as one of the principal contributors to bacterial evolution and diversification. One of the mechanisms involved in this process is conjugative transfer of plasmids and Integrative Conjugative Elements (ICEs). Plasmids and ICEs often encode traits beneficial for bacterial survival in specific environments, or for the establishment of symbiosis or pathoge ...
DOI:: 10.1016/j.plasmid.2017.04.002
: https://doi.org/10.1016/j.plasmid.2017.04.002

80. Relationship between milk cathelicidin abundance and microbiologic culture in clinical mastitis

Author:: M.F. Addis; V. Bronzo; G.M.G. Puggioni; C. Cacciotto; V. Tedde; D. Pagnozzi; C. Locatelli; A. Casula; G. Curone; S. Uzzau; P. Moroni
Source:: Journal of dairy science 2017 v.100 no.4 pp. 2944-2953
ISSN:: 0022-0302
Subject:: Serratia; Streptococcus agalactiae; antibiotics; bovine mastitis; cathelicidins; coagulase negative staphylococci; dairy cows; disease severity; enzyme-linked immunosorbent assay; evolution; microorganisms; milk; pathogens; somatic cell count
Abstract:: ... The availability of reliable tools to enable the sensitive and specific detection of mastitis in dairy cows can assist in developing control strategies and promote the more rational use of antibiotics. We have developed a milk cathelicidin ELISA that shows high sensitivity and specificity for dairy cow mastitis, based on latent class analysis. In this study, we investigated the effect of microbial ...
DOI:: 10.3168/jds.2016-12110
: https://doi.org/10.3168/jds.2016-12110

81. Activation of the σᴱ-Dependent Stress Pathway by Conjugative TraR May Anticipate Conjugational Stress

Author:: Elicia D. Grace; Saumya Gopalkrishnan; Mary E. Girard; Matthew D. Blankschien; Wilma Ross; Richard L. Gourse; Christophe Herman
Source:: Journal of bacteriology 2015 v.197 no.5 pp. 924-931
ISSN:: 0021-9193
Subject:: DNA-directed RNA polymerase; Escherichia coli; antibiotic resistance; antibiotics; bacteria; biosynthesis; evolution; fimbriae; horizontal gene transfer; pathogens; plasmids; protein folding; proteinases; signal transduction; stress response; virulence
Abstract:: ... Horizontal gene transfer by conjugation plays a major role in bacterial evolution, allowing the acquisition of new traits, such as virulence and resistance to antibacterial agents. With the increased antibiotic resistance in bacterial pathogens, a better understanding of how bacteria modulate conjugation under changing environments and the genetic factors involved is needed. Despite the evolutiona ...
DOI:: 10.1128/JB.02279-14
PubMed:: 25535270
PubMed Central:: PMC4325106
: https://doi.org/10.1128/JB.02279-14

82. Antibiotic Adjuvants: Rescuing Antibiotics from Resistance

Author:: Gerard D. Wright
Source:: Trends in microbiology 2016 v.24 no.11 pp. 862-871
ISSN:: 0966-842X
Subject:: adjuvants; antibacterial properties; antibiotic resistance; antibiotics; drugs; evolution; mechanism of action; pathogens
Abstract:: ... Rooted in the mechanism of action of antibiotics and subject to bacterial evolution, antibiotic resistance is difficult and perhaps impossible to overcome. Nevertheless, strategies can be used to minimize the emergence and impact of resistance. Antibiotic adjuvants offer one such approach. These are compounds that have little or no antibiotic activity themselves but act to block resistance or othe ...
DOI:: 10.1016/j.tim.2016.06.009
: https://doi.org/10.1016/j.tim.2016.06.009

83. Antibiotics and evolution: food for thought

Author:: C. R. Strachan; J. Davies
Source:: Journal of industrial microbiology & biotechnology 2016 v.43 no.2-3 pp. 149-153
ISSN:: 1367-5435
Subject:: antibiotics; evolution; molecular weight; polymerization; polypeptides; receptors; secondary metabolites
Abstract:: ... The role of secondary metabolites in effecting and modulating reactions during early biochemical evolution has been largely unappreciated. It is possible that low molecular weight effectors were gradually replaced by polypeptides as polymerizing reactions became more complex, but retained some ability to interact with original receptor sites. Indeed, by reviewing the era of antibiotics in this lig ...
DOI:: 10.1007/s10295-015-1702-x
: https://doi.org/10.1007/s10295-015-1702-x

84. Cold-adapted bacteria from a coastal area of the Ross Sea (Terra Nova Bay, Antarctica): linking microbial ecology to biotechnology

Author:: Angelina Lo Giudice; Renato Fani
Source:: Hydrobiologia 2015 v.761 no.1 pp. 417-441
ISSN:: 0018-8158
Subject:: sediments; bioactive properties; antibiotics; evolution; heavy metals; humans; biotechnology; biochemical pathways; environmental factors; polychlorinated biphenyls; seawater; secondary metabolites; bacterial communities; anthropogenic activities; coasts; temperature; bacteria; Antarctica; Antarctic region
Abstract:: ... This review covers available information concerning the bacterial communities inhabiting coastal areas of Terra Nova Bay (Antarctica). Research was mainly focused on seawater, sediment, and benthic filter feeders. Coping with adverse environmental conditions, Antarctic bacteria have evolved peculiar strategies to survive in this harsh environment. In addition to cellular modifications, antagonisti ...
DOI:: 10.1007/s10750-015-2497-5
: https://doi.org/10.1007/s10750-015-2497-5

85. Collateral sensitivity of antibiotic-resistant microbes

Author:: Csaba Pál; Balázs Papp; Viktória Lázár
Source:: Trends in microbiology 2015 v.23 no.7 pp. 401-407
ISSN:: 0966-842X
Subject:: antibiotic resistance; antibiotics; bacteria; drugs; evolution; multiple drug resistance; mutation; resistance mechanisms; sequence analysis
Abstract:: ... Understanding how evolution of microbial resistance towards a given antibiotic influences susceptibility to other drugs is a challenge of profound importance. By combining laboratory evolution, genome sequencing, and functional analyses, recent works have charted the map of evolutionary trade-offs between antibiotics and have explored the underlying molecular mechanisms. Strikingly, mutations that ...
DOI:: 10.1016/j.tim.2015.02.009
PubMed:: 25818802
PubMed Central:: PMC5958998
: https://doi.org/10.1016/j.tim.2015.02.009

86. Could transformation mechanisms of acetylase-harboring pMdT1 plasmid be evaluated through proteomic tools in Escherichia coli?

Author:: Pedro Magalhães; Luís Pinto; Alexandre Gonçalves; José Eduardo Araújo; Hugo M. Santos; José Luis Capelo; Yolanda Saénz; María de Toro; Carmen Torres; Christophe Chambon; Michel Hébraud; Patrícia Poeta; Gilberto Igrejas
Source:: Journal of proteomics 2016 v.145 pp. 103-111
ISSN:: 1874-3919
Subject:: Escherichia coli; aminoglycosides; antibiotic resistance; antibiotics; bacteria; bioinformatics; electrophoresis; evolution; gastrointestinal system; gene transfer; genes; horizontal gene transfer; humans; liquid chromatography; matrix-assisted laser desorption-ionization mass spectrometry; plasmids; protein synthesis; proteins; proteome; proteomics; resistance mechanisms; tandem mass spectrometry
Abstract:: ... Escherichia coli is a commensal microorganism of the gastrointestinal tract of animals and humans and it is an excellent model organism for the study of antibiotic resistance mechanisms. The resistance transmission and other characteristics of bacteria are based on different types of gene transfer occurring throughout the bacterial evolution. One of which is horizontal gene transfer that allows us ...
DOI:: 10.1016/j.jprot.2016.03.042
: https://doi.org/10.1016/j.jprot.2016.03.042

87. Diversity and variation in antimicrobial susceptibility patterns over time in Mycoplasma agalactiae isolates collected from sheep and goats in France

Author:: F. Poumarat; A.V. Gautier‐Bouchardon; D. Bergonier; E. Gay; F. Tardy
Source:: Journal of applied microbiology 2016 v.120 no.5 pp. 1208-1218
ISSN:: 1364-5072
Subject:: Mycoplasma agalactiae; Mycoplasma bovis; agalactia; antibiotic resistance; antibiotics; cattle; dairy industry; evolution; financial economics; fluoroquinolones; genetic background; genetic relationships; genetic variation; goats; macrolides; minimum inhibitory concentration; pathogens; sheep; France
Abstract:: ... AIMS: Mycoplasma agalactiae is responsible for Contagious Agalactia, a severe syndrome affecting small ruminants worldwide and resulting in significant economic losses in countries with an important dairy industry. The aim of this study was to examine the antimicrobial susceptibility patterns of M. agalactiae isolates in France, their evolution over the last 25 years and their relationships with t ...
DOI:: 10.1111/jam.13083
: https://doi.org/10.1111/jam.13083

88. Exploring the potential impact of an expanded genetic code on protein function

Author:: Han Xiao; Fariborz Nasertorabi; Sei-hyun Choi; Gye Won Han; Sean A. Reed; Raymond C. Stevens; Peter G. Schultz
Source:: Proceedings of the National Academy of Sciences of the United States of America 2015 v.112 no.22 pp. 6961-6966
ISSN:: 0027-8424
Subject:: amino acids; antibiotics; beta-lactamase; catalytic activity; evolution; genetic code; mutants; mutation
Abstract:: ... With few exceptions, all living organisms encode the same 20 canonical amino acids; however, it remains an open question whether organisms with additional amino acids beyond the common 20 might have an evolutionary advantage. Here, we begin to test that notion by making a large library of mutant enzymes in which 10 structurally distinct noncanonical amino acids were substituted at single sites ran ...
DOI:: 10.1073/pnas.1507741112
PubMed:: 26038548
PubMed Central:: PMC4460475
: https://doi.org/10.1073/pnas.1507741112

89. Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition

Author:: Susu He; Alison Burgess Hickman; Alessandro M. Varani; Patricia Siguier; Michael Chandler; John P. Dekker; Fred Dyda
Source:: mBio 2015 v.6 no.3 pp. e00762-15
ISSN:: 2150-7511
Subject:: Enterobacteriaceae; National Institutes of Health; antibiotic resistance; antibiotics; bacteria; beta-lactamase; evolution; genes; monitoring; multiple drug resistance; phenotype; plasmids; public health; replicon; transposition (genetics); transposons
Abstract:: ... Carbapenemase-producing Enterobacteriaceae (CPE), which are resistant to most or all known antibiotics, constitute a global threat to public health. Transposable elements are often associated with antibiotic resistance determinants, suggesting a role in the emergence of resistance. One insertion sequence, IS 26 , is frequently associated with resistance determinants, but its role remains unclear. ...
DOI:: 10.1128/mBio.00762-15
PubMed:: 26060276
PubMed Central:: PMC4471558
: https://doi.org/10.1128/mBio.00762-15

90. Interpreting phenotypic antibiotic tolerance and persister cells as evolution via epigenetic inheritance

Author:: Troy Day
Source:: Molecular ecology 2016 v.25 no.8 pp. 1869-1882
ISSN:: 0962-1083
Subject:: RNA; antibiotic resistance; antibiotics; bacteria; epigenetics; evolution; gene expression; models; parents; phenotype; progeny
Abstract:: ... Epigenetic inheritance is the transmission of nongenetic material such as gene expression levels, RNA and other biomolecules from parents to offspring. There is a growing realization that such forms of inheritance can play an important role in evolution. Bacteria represent a prime example of epigenetic inheritance because a large array of cellular components is transmitted to offspring, in additio ...
DOI:: 10.1111/mec.13603
PubMed:: 26946044
PubMed Central:: PMC4846567
: https://doi.org/10.1111/mec.13603

91. Isolation, genome sequencing and functional analysis of two T7-like coliphages of avian pathogenic Escherichia coli

Author:: Mianmian Chen; Juntian Xu; Huochun Yao; Chengping Lu; Wei Zhang
Source:: Gene 2016 v.582 no.1 pp. 47-58
ISSN:: 0378-1119
Subject:: DNA; Enterobacteria phages; Erwinia; Escherichia coli; Kluyvera; Podoviridae; antibiotic resistance; antibiotics; bacteria; birds; coliphages; drug residues; electron microscopy; evolution; farmers; feces; financial economics; genes; genomics; high-throughput nucleotide sequencing; markets; poultry industry; proteins; sequence homology; China
Abstract:: ... Avian pathogenic Escherichia coli (APEC) causes colibacillosis, which results in significant economic losses to the poultry industry worldwide. Due to the drug residues and increased antibiotic resistance caused by antibiotic use, bacteriophages and other alternative therapeutic agents are expected to control APEC infection in poultry.Two APEC phages, named P483 and P694, were isolated from the fe ...
DOI:: 10.1016/j.gene.2016.01.049
: https://doi.org/10.1016/j.gene.2016.01.049

92. Mechanisms of genome evolution of Streptococcus

Author:: Cheryl P. Andam; William P. Hanage
Source:: Infection, genetics, and evolution 2015 v.33 pp. 334-342
ISSN:: 1567-1348
Subject:: Streptococcus pneumoniae; antibiotic resistance; antibiotics; disease control; evolution; genes; genomics; horizontal gene transfer; hosts; humans; pathogenicity; pathogens; phenotypic variation; population dynamics; respiratory system; serotypes; vaccines
Abstract:: ... The genus Streptococcus contains 104 recognized species, many of which are associated with human or animal hosts. A globally prevalent human pathogen in this group is Streptococcus pneumoniae (the pneumococcus). While being a common resident of the upper respiratory tract, it is also a major cause of otitis media, pneumonia, bacteremia and meningitis, accounting for a high burden of morbidity and ...
DOI:: 10.1016/j.meegid.2014.11.007
PubMed:: 25461843
PubMed Central:: PMC4430445
: https://doi.org/10.1016/j.meegid.2014.11.007

93. Microbial Consortium Associated with the Antarctic Marine Ciliate Euplotes focardii: An Investigation from Genomic Sequences

Author:: Sandra Pucciarelli; Raghul Rajan Devaraj; Alessio Mancini; Patrizia Ballarini; Michele Castelli; Martina Schrallhammer; Giulio Petroni; Cristina Miceli
Source:: Microbial ecology 2015 v.70 no.2 pp. 484-497
ISSN:: 0095-3628
Subject:: Francisella; antibiotics; antifreeze proteins; bacteria; cell division; cold; energy; enzymes; evolution; genes; metabolism; nucleotide sequences; Antarctic region; Antarctica
Abstract:: ... We report the characterization of the bacterial consortium associated to Euplotes focardii, a strictly psychrophilic marine ciliate that was maintained in laboratory cultures at 4 °C after its first isolation from Terra Nova Bay, in Antarctica. By Illumina genome analyser, we obtained 11,179 contigs of potential prokaryotic origin and classified them according to the NCBI’s prokaryotic attributes ...
DOI:: 10.1007/s00248-015-0568-9
PubMed:: 25704316
PubMed Central:: PMC4494151
: https://doi.org/10.1007/s00248-015-0568-9

94. Targets for Combating the Evolution of Acquired Antibiotic Resistance

Author:: Culyba Matthew J.; Mo Charlie Y.; Kohli Rahul M.
Source:: Biochemistry 2015 v.54 no.23 pp. 3573-3582
ISSN:: 1520-4995
Subject:: antibiotic resistance; antibiotics; bacteria; biochemistry; drugs; evolution; horizontal gene transfer; pathogens; viability
Abstract:: ... Bacteria possess a remarkable ability to rapidly adapt and evolve in response to antibiotics. Acquired antibiotic resistance can arise by multiple mechanisms but commonly involves altering the target site of the drug, enzymatically inactivating the drug, or preventing the drug from accessing its target. These mechanisms involve new genetic changes in the pathogen leading to heritable resistance. T ...
DOI:: 10.1021/acs.biochem.5b00109
PubMed:: 26016604
PubMed Central:: PMC4471857
: https://doi.org/10.1021/acs.biochem.5b00109

95. Water Disinfection Byproducts Induce Antibiotic Resistance-Role of Environmental Pollutants in Resistance Phenomena

Author:: Li Dan; Zeng Siyu; He Miao; Gu April Z.
Source:: Environmental Science & Technology 2016 v.50 no.6 pp. 3193-3201
ISSN:: 1520-5851
Subject:: Escherichia coli; antibiotic resistance; antibiotics; byproducts; disinfection; drugs; evolution; genes; iodoacetic acid; minimum inhibitory concentration; mutation; pollutants; public health
Abstract:: ... The spread of antibiotic resistance represents a global threat to public health, and has been traditionally attributed to extensive antibiotic uses in clinical and agricultural applications. As a result, researchers have mostly focused on clinically relevant high-level resistance enriched by antibiotics above the minimal inhibitory concentrations (MICs). Here, we report that two common water disin ...
DOI:: 10.1021/acs.est.5b05113
PubMed:: 26928861
PubMed Central:: PMC6321747
: https://doi.org/10.1021/acs.est.5b05113

96. A gene cluster for the biosynthesis of moenomycin family antibiotics in the genome of teicoplanin producer Actinoplanes teichomyceticus

Author:: Liliya Horbal; Bohdan Ostash; Andriy Luzhetskyy; Suzanne Walker; Jorn Kalinowski; Victor Fedorenko
Source:: Applied microbiology and biotechnology 2016 v.100 no.17 pp. 7629-7638
ISSN:: 0175-7598
Subject:: Actinoplanes teichomyceticus; Streptomyces clavuligerus; Streptomyces ghanaensis; animal nutrition; antibiotics; biochemical pathways; biosynthesis; engineering; evolution; mechanism of action; microorganisms; multigene family; structural genes; structure-activity relationships
Abstract:: ... Moenomycins are phosphoglycolipid antibiotics notable for their extreme potency, unique mode of action, and proven record of use in animal nutrition without selection for resistant microflora. There is a keen interest in manipulation of structures of moenomycins in order to better understand their structure-activity relationships and to generate improved analogs. Only two almost identical moenomyc ...
DOI:: 10.1007/s00253-016-7685-3
: https://doi.org/10.1007/s00253-016-7685-3

97. The mechanisms whereby the green alga Chlorella ohadii, isolated from desert soil crust, exhibits unparalleled photodamage resistance

Author:: Haim Treves; Hagai Raanan; Isaac Kedem; Omer Murik; Nir Keren; Hagit Zer; Simon M. Berkowicz; Mario Giordano; Alessandra Norici; Yoram Shotland; Itzhak Ohad; Aaron Kaplan
Source:: new phytologist 2016 v.210 no.4 pp. 1229-1243
ISSN:: 0028-646X
Subject:: Chlorella; D1 protein; antibiotics; carbohydrate content; carbon cycle; carotenes; crops; desert soils; energy; evolution; genes; irradiation; lighting; lipids; oxygen production; photoinhibition; photosystem II; reducing agents; singlet oxygen; soil crusts; solar radiation; spectroscopy
Abstract:: ... Excess illumination damages the photosynthetic apparatus with severe implications with regard to plant productivity. Unlike model organisms, the growth of Chlorella ohadii, isolated from desert soil crust, remains unchanged and photosynthetic O₂ evolution increases, even when exposed to irradiation twice that of maximal sunlight. Spectroscopic, biochemical and molecular approaches were applied to ...
DOI:: 10.1111/nph.13870
: https://doi.org/10.1111/nph.13870

98. Antibiotic-Induced Replication Stress Triggers Bacterial Competence by Increasing Gene Dosage near the Origin

Author:: Jelle Slager; Morten Kjos; Laetitia Attaiech; Jan-Willem Veening
Source:: Cell 2014 v.157 pp. 395-406
ISSN:: 0092-8674
Subject:: DNA; DNA replication; Streptococcus pneumoniae; antibiotic resistance; antibiotics; bacteria; children; evolution; gene dosage; gene expression; genes; human health; replication origin; transcriptome
Abstract:: ... Streptococcus pneumoniae (pneumococcus) kills nearly 1 million children annually, and the emergence of antibiotic-resistant strains poses a serious threat to human health. Because pneumococci can take up DNA from their environment by a process called competence, genes associated with antibiotic resistance can rapidly spread. Remarkably, competence is activated in response to several antibiotics. H ...
DOI:: 10.1016/j.cell.2014.01.068
: https://doi.org/10.1016/j.cell.2014.01.068

99. Antimicrobial interactions: mechanisms and implications for drug discovery and resistance evolution

Author:: Tobias Bollenbach
Source:: Current opinion in microbiology 2015 v.27 pp. 1-9
ISSN:: 1369-5274
Subject:: antibiotics; cell physiology; combination drug therapy; drug interactions; drugs; evolution; prediction
Abstract:: ... Combining antibiotics is a promising strategy for increasing treatment efficacy and for controlling resistance evolution. When drugs are combined, their effects on cells may be amplified or weakened, that is the drugs may show synergistic or antagonistic interactions. Recent work revealed the underlying mechanisms of such drug interactions by elucidating the drugs’ joint effects on cell physiology ...
DOI:: 10.1016/j.mib.2015.05.008
: https://doi.org/10.1016/j.mib.2015.05.008

100. Comparative morpho-physiology of the metapleural glands of two Atta leaf-cutting ant queens nesting in clayish and organic soils

Author:: Alexsandro Santana Vieira; Maria Izabel Camargo-Mathias; Flavio Roces
Source:: Arthropod structure & development 2015 v.44 no.5 pp. 444-454
ISSN:: 1467-8039
Subject:: Atta sexdens rubropilosa; antibiotics; antiseptics; evolution; fungus gardens; leaf-cutting ants; microorganisms; nesting; organic matter; organic soils; pathogens; queen insects; risk; soil depth; soil horizons
Abstract:: ... Queens of leaf-cutting ants found their nests singly, each consisting of a vertical tunnel and a final horizontal chamber. Because of the claustral mode of nest founding, the queen and/or her initial fungus garden are exposed to threats imposed by several soil pathogens, and the antibiotic secretions produced by their metapleural glands are considered a main adaptation to deal with them. Nests of ...
DOI:: 10.1016/j.asd.2015.06.005
: https://doi.org/10.1016/j.asd.2015.06.005

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1. Changes in the Oxidative Stress Status of Dogs Affected by Acute Enteropathies

2. Differences in recipient ability of uropathogenic Escherichia coli strains in relation with their pathogenic potential

3. Dissecting the roles of conductive materials in attenuating antibiotic resistance genes: Evolution of physiological features and bacterial community

4. Metagenomic insights into the profile of antibiotic resistomes in sediments of aquaculture wastewater treatment system

5. Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches

6. Suppressing evolution of antibiotic resistance through environmental switching

7. Temporin B Forms Hetero-Oligomers with Temporin L, Modifies Its Membrane Activity, and Increases the Cooperativity of Its Antibacterial Pharmacodynamic Profile

8. Antibiotic resistome in the livestock and aquaculture industries: Status and solutions

9. Distribution and transfer of antibiotic resistance genes in different soil–plant systems

10. Effects of various antibiotics on aerobic nitrogen removal and antibiotic degradation performance: Mechanism, degradation pathways, and microbial community evolution

11. Enhancing recovery performance of the toluene-removing biofilter after the short/long interference-shutdown period

12. Impact of bacterial persisters on their host

13. Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements

14. Molecular basis of cycloheximide resistance in the Ophiostomatales revealed

15. Occurrences, transport drivers, and risk assessments of antibiotics in typical oasis surface and groundwater

16. Performance of Holstein calves receiving increased nutrient intake through the addition of skim milk or milk replacer powder to the whole milk

17. Unexpected distribution of the 4-formylaminooxyvinylglycine (FVG) biosynthetic pathway in Pseudomonas and beyond

18. Urbanization drives the succession of antibiotic resistome and microbiome in a river watershed

19. The evolutionary trade‐offs in phage‐resistant Klebsiella pneumoniae entail cross‐phage sensitization and loss of multidrug resistance

20. Candida albicans, a reservoir of Listeria monocytogenes?

21. Complete genome sequence and epigenetic profile of Bacillus velezensis UCMB5140 used for plant and crop protection in comparison with other plant-associated Bacillus strains

22. Composition of nutrient media and temperature of cultivation imposes effect on the content of secondary metabolites of Nocardiopsis sp. isolated from a Siberian Cave

23. Development of a Convergent Enantioselective Synthetic Route to (−)-Myrocin G

24. Energy- and cost-effective non-sterilized fermentation of 2,3-butanediol by an engineered Klebsiella pneumoniae OU7 with an anti-microbial contamination system

25. Evolution of Antibacterial Drug Screening Methods: Current Prospects for Mycobacteria

26. Evolution of surviving Streptoccocus pyogenes from pharyngotonsillitis patients submit to multiple cycles of antimicrobial photodynamic therapy

27. Genome Sequence and Characterization of Five Bacteriophages Infecting Streptomyces coelicolor and Streptomyces venezuelae: Alderaan, Coruscant, Dagobah, Endor1 and Endor2

28. Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with Escherichia coli

29. High frequency and diversity of Vancomycin-resistant Enterococci (VRE) in Algerian healthcare settings

30. High occurrence of heavy metal tolerance genes in bacteria isolated from wastewater: A new concern?

31. Inhibitory effects of aptamer targeted teicoplanin encapsulated PLGA nanoparticles for Staphylococcus aureus strains

32. Natural and synthetic plant compounds as anti-biofilm agents against Escherichia coli O157:H7 biofilm

33. Occurrence of antibiotics and antibiotic resistance genes in the Fuxian Lake and antibiotic source analysis based on principal component analysis-multiple linear regression model

34. Pan-proteome profiling of emerging and re-emerging zoonotic pathogen Orientia tsutsugamushi for getting insight into microbial pathogenesis

35. Quantitative biology of survival under antibiotic treatments

36. The Role of QuantiFERON-TB Gold Plus in Mycobacterium Tuberculosis Detection in a Severe HIV Immunocompromised Patient—Case Report

37. Targeting evolution of antibiotic resistance by SOS response inhibition

38. ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life

39. Biodegradable Antimicrobial Food Packaging: Trends and Perspectives

40. Comparing the selective and co-selective effects of different antimicrobials in bacterial communities

41. The Complexity of the Holobiont in the Red Sea Coral Euphyllia paradivisa under Heat Stress

42. Culturing Ancient Bacteria Carrying Resistance Genes from Permafrost and Comparative Genomics with Modern Isolates

43. Does Soil Contribute to the Human Gut Microbiome?

44. Emerging evolutionary paradigms in antibiotic discovery

45. Genetic parameters of resistance to pasteurellosis using novel response traits in rabbits

46. Horizontal transfer of antibiotic resistance genes in clinical environments

47. Local applications but global implications: Can pesticides drive microorganisms to develop antimicrobial resistance?

48. Medical leech therapy in Ayurveda and biomedicine – A review

49. Spatial distribution of antibiotic and heavy metal resistance genes in the Black Sea

50. Therapeutic lipid-coated hybrid nanoparticles against bacterial infections

51. Tildipirosin: An effective antibiotic against Glaesserella parasuis from an in vitro analysis

52. Toward a chimeric vaccine against multiple isolates of Mycobacteroides - An integrative approach

53. The dynamic of antibiotic resistance in commensal Escherichia coli throughout the growing period in broiler chickens: fast-growing vs. slow-growing breeds

54. The impact and mechanism of quaternary ammonium compounds on the transmission of antibiotic resistance genes

55. Application of biosolids drives the diversity of antibiotic resistance genes in soil and lettuce at harvest

56. Characterization and genome analysis of the temperate bacteriophage φSAJS1 from Streptomyces avermitilis

57. Comparative proteomics analyses of Acinetobacter baumannii strains ATCC 17978 and AB5075 reveal the differential role of type II secretion system secretomes in lung colonization and ciprofloxacin resistance

58. Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance

59. Detection of Extended-Spectrum β-Lactamase-Producing Escherichia coli Using Infrared Microscopy and Machine-Learning Algorithms

60. Distribution of antibiotic resistance and virulence factors among the bacteria isolated from diseased Etroplus suratensis

61. Evolution of structural fitness and multifunctional aspects of mycobacterial RND family transporters

62. Inhibiting the Evolution of Antibiotic Resistance

63. New Selectable Markers for Volvox carteri Transformation

64. Silver nanoparticles as antimicrobial therapeutics: current perspectives and future challenges

65. The scent of symbiosis: gut bacteria may affect social interactions in leaf-cutting ants

66. Staphylococcus aureus Sequences from Osteomyelitic Specimens of a Pathological Bone Collection from Pre-Antibiotic Times

67. Comparative genome analysis of IncHI2 VIM-1 carbapenemase-encoding plasmids of Escherichia coli and Salmonella enterica isolated from a livestock farm in Germany

68. Confronting herbicide resistance with cooperative management

69. Evolutionary Mechanisms Shaping the Maintenance of Antibiotic Resistance

70. Plasmid and clonal interference during post horizontal gene transfer evolution