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You searched for: Subject exosomes Remove constraint Subject: exosomes Subject leukemia Remove constraint Subject: leukemia Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Bone marrow‐mesenchymal stem cell‐derived extracellular vesicles affect proliferation and apoptosis of leukemia cells in vitro

Author:
Jitrada Phetfong; Tulyapruek Tawonsawatruk; Witchayapon Kamprom; Pawared Ontong; Dalina Tanyong; Suparerk Borwornpinyo; Aungkura Supokawej
Source:
FEBS Open Bio 2022 v.12 no.2 pp. 470-479
ISSN:
2211-5463
Subject:
apoptosis; carcinogenesis; cell cycle; cell differentiation; cell growth; cell proliferation; death domain receptors; exosomes; gene expression; gene expression regulation; genes; immune system; leukemia; molecular weight; therapeutics; ultrafiltration
Abstract:
... Mesenchymal stem cells (MSCs) have been proposed to have potential for tissue engineering and cell therapy due to their multilineage differentiation potential and ability to secrete numerous paracrine factors, including extracellular vesicles (EVs). Increasing evidence has demonstrated that MSC‐derived EVs (MSC‐EVs) are able to induce the repair of tissue damage and regulate the immune system. How ...
DOI:
10.1002/2211-5463.13352

2. Contribution of extracellular vesicles in normal hematopoiesis and hematological malignancies

Author:
Soudeh Ghafouri-Fard; Vahid Niazi; Mohammad Taheri
Source:
Heliyon 2021 v.7 no.1 pp. e06030
ISSN:
2405-8440
Subject:
bone marrow; endosomes; exosomes; hematopoiesis; leukemia; lipids; medicine; megakaryocytes; myeloma; pathogenesis; plasma membrane; therapeutics
Abstract:
... Extracellular vesicles (EVs) are lipid bilayer-enclosed microparticles that have prominent roles in the intercellular crosstalk. EVs are secreted after fusion of endosomes with the plasma membrane (exosomes) or shed from the plasma membrane (microvesicles). These microparticles modulate bone marrow microenvironment and alter differentiation and expansion of normal hematopoietic cells. EVs originat ...
DOI:
10.1016/j.heliyon.2021.e06030

3. Do exosomes play role in cardiovascular disease development in hematological malignancy?

Author:
Fatemeh Javaherforoosh Zadeh; Yasmin Ghasemi; Saeede Bagheri; Mohsen Maleknia; Nader Davari; Hadi Rezaeeyan
Source:
Molecular biology reports 2020 v.47 no.7 pp. 5487-5493
ISSN:
0301-4851
Subject:
angiogenesis; cardiomyocytes; cardiovascular diseases; exosomes; leukemia; molecular biology; pathogenesis
Abstract:
... Exosomes play a role in the pathogenesis and treatment of malignancies as a double-edged sword. Recently, researchers discussed about two new roles, cardiomyocyte function impairment and cardiovascular disease (CVD) genesis. Data were collected from PUBMED at various time points up to the 2019 academic year. The related key words are listed as following; “Arsenic trioxide”, “acute promyelocytic le ...
DOI:
10.1007/s11033-020-05453-z

4. K562 cell-derived exosomes suppress the adhesive function of bone marrow mesenchymal stem cells via delivery of miR-711

Author:
Yu-Huan Jiang; Jing Liu; Jin Lin; Shu-Qi Li; Yan-Mei Xu; Qing-Hua Min; Qiong-Hui Zhong; Fan Sun; Jing Li; Xia-Hong You; Kai-Li Liao; Ting-Yu Qin; Cui Zhao; Bo Huang; Xiao-Zhong Wang
Source:
Biochemical and biophysical research communications 2020 v.521 no.3 pp. 584-589
ISSN:
0006-291X
Subject:
adhesion; bone marrow; coculture; exosomes; leukemia; microRNA; research
Abstract:
... A failure of bone marrow mesenchymal stem cells (BM-MSCs) to adhere to hematopoietic cells is an essential cause of the progression of chronic myelogenous leukemia and is also a cause of failure of bone marrow (BM) transplantation, but the exact mechanisms of this have not been fully elucidated. Recent studies have indicated that microRNAs (miRNAs) are contained in leukemia-derived exosomes and ar ...
DOI:
10.1016/j.bbrc.2019.10.096

5. Rolling circle amplification assisted dual signal amplification colorimetric biosensor for ultrasensitive detection of leukemia-derived exosomes

Author:
Chao Li; Mengyang Zhou; Haoyu Wang; Jie Wang; Lin Huang
Source:
Talanta 2022 v.245 pp. 123444
ISSN:
0039-9140
Subject:
biopsy; biosensors; blood serum; color; colorimetry; detection limit; exosomes; leukemia; magnetism; nanogold
Abstract:
... Tumor-derived exosomes as a liquid biopsy marker hold great promising for the accurate tumor diagnosis. However, the visual exosomes detection method with high sensitivity and convenience is still a challenge and highly valuable in the clinical application. Herein, we fabricated a colorimetric biosensor that could visually detect leukemia-derived exosomes, and dual amplified the signal based on th ...
DOI:
10.1016/j.talanta.2022.123444