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1. Anti-Proliferative Naphthalene Glucoside from Aerial Part of Neanotis wightiana

Author:
Niranjan Das; Prashanta Kumar Deb; Eunus S. Ali; Manash C. Das; Biswatrish Sarkar; Siddhartha Kumar Mishra
Source:
Chemistry of natural compounds 2022 v.58 no.1 pp. 21-26
ISSN:
0009-3130
Subject:
aerial parts; breast neoplasms; chemistry; cytotoxicity; glucosides; humans; naphthalene; neoplasm cells; spectral analysis
Abstract:
... A new bioactive naphthalene glucoside, named neanoside C (1), was isolated from the aerial part of Neanotis wightiana. The structure of neanoside C (1) was elucidated as 1,4-dihydroxy-2-(6′-Omethylglucopyranosyloxymethyl)-naphthalene-3-vinyloxyglucopyranoside by interpretation of the spectroscopic data, including 2D NMR and chemical studies. Neanoside C (1) was further subjected to screening for a ...
DOI:
10.1007/s10600-022-03591-3

2. Cannadicas A and B: two new oligosaccharide esters from the roots of Canna indica L.

Author:
Luu The Anh; Nguyen Hieu; Do Thi Trang; Bui Huu Tai; Nguyen Xuan Nhiem; Phan Van Kiem
Source:
Natural product research 2022 v.36 no.14 pp. 3559-3566
ISSN:
1478-6427
Subject:
Canna indica; absorbance; antioxidant activity; chromatography; glucosides; research; spectral analysis; sucrose
Abstract:
... Two new sucrose derivatives, named as cannadica A (1) and cannadica B (2), and eight known compounds, 6′-O-acetyl-3-O-(E)-p-coumaroylsucrose (3), heterophylloside C (4), 6′-O-vanilloylarbutin (5), isotachioside (6), 2,6-dimethoxy-p-hydroquinone 1-O-β-D-glucopyranoside (7), 3,5-dimethoxy-p-hydroquinone 1-O-β-D-glucopyranoside (8), benzyl glucoside (9), and 3,4-dihydroxybenzaldehyde (10) were isolat ...
DOI:
10.1080/14786419.2020.1869232

3. Chemical constituents and absolute configuration of megastigmanes’ isolated from Sedum sarmentosum Bunge

Author:
Dinh Xuan Doan; Sijia Sun; Ashraf M. Omar; Dong Thuong Nguyen; Anh Le Tuan Hoang; Hironori Fujiwara; Kinzo Matsumoto; Hang Thi Nguyet Pham; Suresh Awale
Source:
Natural product research 2022 v.36 no.9 pp. 2341-2348
ISSN:
1478-6427
Subject:
Sedum sarmentosum; acid hydrolysis; cytotoxicity; glucosides; human cell lines; norisoprenoids; phytochemicals; research; spectral analysis; uterine cervical neoplasms; Vietnam
Abstract:
... Phytochemical investigation of a methanolic extract of Sedum sarmentosum collected from Vietnam resulted in the isolation of a new megastigmane glucoside, named sedumoside K (1), together with 17 previously reported compounds (2–18). Structural elucidation of the new compound was achieved by HRFABMS, NMR spectroscopic analysis, acid hydrolysis and quantum ECD calculations. The absolute configurati ...
DOI:
10.1080/14786419.2020.1834549

4. Chemical constituents and aldose reductase inhibitory activities of Betula alba bark and leaves

Author:
Tomoki Iguchi; Minpei Kuroda; Nanami Akiyama; Mariko Hashimoto; Yoshihiro Mimaki
Source:
Natural product research 2022 v.36 no.4 pp. 1004-1008
ISSN:
1478-6427
Subject:
Betula pubescens var. pubescens; aldehyde reductase; bark; flavanones; glucosides; lignans; methyl salicylate; monoterpenoids; research; spectral analysis; triterpenoids
Abstract:
... Systematic phytochemical investigation of the bark and leaves of Betula alba was independently conducted. A new cyclic diarylheptanoid glucoside (1), five diarylheptanoids (2–6), a phenylethanoid (7), a methyl salicylate glycoside (8), a dihydrobenzofuran glucoside (9), an arylbutanoid glycoside (10), two lignan glycosides (11 and 12), a flavanone glucoside (13), and a triterpene (14) were isolate ...
DOI:
10.1080/14786419.2020.1839455

5. Four new triterpene glucosides from Salacia cochinchinensis Lour

Author:
Lu Gao; Li-Kun Duan; Jin-E Feng; Yun-Tao Jiang; Jun Gao; Jun-Ting Fan; Rong Dai; Zhi-Yong Jiang
Source:
Natural product research 2022 v.36 no.9 pp. 2292-2299
ISSN:
1478-6427
Subject:
Salacia; ethanol; glucosides; research; spectral analysis; triterpenoids
Abstract:
... Four new triterpene glucosides (1–4) were isolated from the 90% ethanol extract of Salacia cochinchinensis, together with five known compounds (5–9). The structures of the new compounds were elucidated by comprehensive spectroscopic analysis including HRESIMS, IR, 1 D and 2 D NMR analysis. All isolates were assayed for their α-glucosidase inhibitory activity. Compound 9 showed remarkable α-glucosi ...
DOI:
10.1080/14786419.2020.1830393

6. Further Study on Chemical Constituents from the Seeds of Michelia hedyosperma

Author:
Hai-jun Wang; Li-na Qin; Ming-Zhu Li; Xian-you Wang
Source:
Chemistry of natural compounds 2022 v.58 no.1 pp. 75-77
ISSN:
0009-3130
Subject:
Magnolia hypolampra; glucosides; spectral analysis
Abstract:
... A new phenylpropanoid glucoside, michehedyoside G (1), together with two known compounds, including 9-(β-D-ribofuranosyl)-adenosine (2) and (±)-1,2-methylenedioxy-4-(1,2,3-trihydroxypropyl)-benzene (3), were isolated from the seeds of Michelia hedyosperma Y. W. Law (Magnoliaceae). Their structures were confirmed by comprehensive spectroscopic analysis. ...
DOI:
10.1007/s10600-022-03599-9

7. A New Anti-Endometrial Cancer Diterpenoid Glucoside from Sheareria nana

Author:
Zhongyan Tang; Zhengxiang Xia
Source:
Chemistry of natural compounds 2022 v.58 no.5 pp. 870-873
ISSN:
0009-3130
Subject:
carcinoma; cell lines; chemistry; cytotoxicity; diterpenoids; endometrium; glucosides; humans; inhibitory concentration 50; spectral analysis
Abstract:
... A new diterpenoid glucoside, 15,16-dihydroxy-4-formyl-neo-clerodane-3,13 (Z)-dien-17-O-β-Dglucopyranosyl (1), was isolated from Sheareria nana S. Moore. The structure was elucidated by spectroscopic data. 1 was evaluated for cytotoxic activities against human endometrial carcinoma cells (Ishikawa and ECC-1). The results suggested that 1 exhibited moderate cytotoxic activity against Ishikawa and EC ...
DOI:
10.1007/s10600-022-03819-2

8. New phenolics from Uraria crinita (L.) DC

Author:
Dao Duc Thien; Bui Huu Tai; Tran Duc Dai; Nguyen Hoang Sa; Trinh Thi Thuy; Nguyen Thi Hoang Anh; Nguyen Thanh Tam
Source:
Natural product research 2022 v.36 no.13 pp. 3381-3388
ISSN:
1478-6427
Subject:
Uraria crinita; acid hydrolysis; apigenin; cytotoxicity; glucosides; methanol; phenolic compounds; research; spectral analysis
Abstract:
... Reinvestigation of a methanol extract of Uraria crinita afforded a new 3- hydroxyisoflavanone, 3,5,7,2',4'-pentahydroxyisoflavanone (1), two new monoaryl glucosides, 3,4-dimethoxyphenyl 1-O-(6′-O-acetyl)-β-D-glucopyranoside (2) and 3,4,5-trimethoxyphenyl 1-O-(6′-O-acetyl)-β-D-glucopyranoside (3), in addition to three known compounds, 3′-O-methylorobol (4), robusflavone B (5), and apigenin (6). The ...
DOI:
10.1080/14786419.2020.1860973

9. PTP1B and α-glucosidase inhibitory activities of the chemical constituents from Hedera rhombea fruits: Kinetic analysis and molecular docking simulation

Author:
Manh Tuan Ha; Tae Hyun Lee; Chung Sub Kim; Ritu Prajapati; Jeong Ah Kim; Jae Sue Choi; Byung Sun Min
Source:
Phytochemistry 2022 v.197 pp. 113100
ISSN:
0031-9422
Subject:
Hedera rhombea; acarbose; beans; enzyme kinetics; fruits; glucosides; kinetics; noninsulin-dependent diabetes mellitus; plant biochemistry; quinic acid; sodium; spectral analysis; ursolic acid
Abstract:
... In this study, we present the first investigation of Hedera rhombea Bean fruit, which led to the isolation of six undescribed compounds including two megastigmane glucosides, two rare 1,4-dioxane neolignanes, and two quinic acid derivatives, together with 26 known compounds. Their structures and absolute configurations were elucidated by extensive analysis of NMR spectroscopic data, HRMS, and ECD ...
DOI:
10.1016/j.phytochem.2022.113100

10. Phenylpropanoid-conjugated iridoid glucosides from leaves of Morinda morindoides

Author:
Yasinjan Hashim; Kazufumi Toume; Shusaku Mizukami; Toshinori Kitami; Mayumi Taniguchi; Awet Alem Teklemichael; Yuki Tayama; Nguyen Tien Huy; José Nzunzu Lami; Joseph M. Bodi; Kenji Hirayama; Katsuko Komatsu
Source:
Natural medicines 2022 v.76 no.1 pp. 281-290
ISSN:
1340-3443
Subject:
Morinda morindoides; Plasmodium falciparum; Trypanosoma cruzi; antitrypanosomal properties; cytotoxicity; flavonoids; glucosides; heart; iridoid glycosides; mice; spectral analysis
Abstract:
... Three phenylpropanoid-conjugated iridoid glucosides, acetylgaertneric acid (1), acetyldehydrogaertneroside (2), and dehydrogaertneric acid (10), together with nine known related iridoid glucosides (3–9, 11, and 12), two coumaroyl alkaloids, one benzenoid, and three flavonoid glucosides were isolated from leaves of Morinda morindoides (Rubiaceae). Structures of these isolated compounds were determi ...
DOI:
10.1007/s11418-021-01567-1

11. Secondary metabolites from Detarium microcarpum Guill. and Perr. (Fabaceae)

Author:
William Fouatio Feudjou; Arnaud Michel Mbock; Valerie Tedjon Sielinou; Hugue Fouotsa; Steven Collins Njonté Wouamba; Racéline Kamkumo Gounoue; Marcel Freeze; Hans-Georg Stammler; Jean Jules Kezeutas Bankeu; Mkounga Pierre; Bruno Ndjakou Lenta; Alembert Tiabou Tchinda; Norbert Sewald; Augustin Ephrem Nkengfack
Source:
Zeitschrift für Naturforschung 2022 v.77 no.5-6 pp. 253-261
ISSN:
1865-7125
Subject:
Detarium microcarpum; Salmonella Enteritidis; Salmonella Typhi; ceramides; ethanol; glucosides; labdane; minimum inhibitory concentration; secondary metabolites; spectral analysis; stigmasterol; ursolic acid
Abstract:
... The chemical investigation of the ethanol/water (7:3) extract of the roots of Detarium microcarpum (Fabaceae) led to the isolation of one new labdane diterpenoid, microcarpin (1) and one new ceramide derivative, microcarpamide (2), along with eight known secondary metabolites (3–10) including, 5-(carboxymethyl)-5,6,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalene-1-carboxylic acid (3), microcar ...
DOI:
10.1515/znc-2021-0239

12. Thannilignan glucoside and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative, two new compounds isolated from Terminalia bellirica

Author:
Teruhisa Manome; Yasumasa Hara; Firoj Ahmed; Samir K. Sadhu; Masami Ishibashi
Source:
Natural medicines 2022 v.76 no.2 pp. 482-489
ISSN:
1340-3443
Subject:
Terminalia bellirica; cytotoxicity; glucosides; humans; ligands; methanol; necrosis; neoplasm cells; neoplasms; spectral analysis; Bangladesh
Abstract:
... Two new compounds, thannilignan 9-O-β-glucoside (1) and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative (2), and seven known compounds were isolated from the methanol extract of Terminalia bellirica leaves, collected in Bangladesh. The structures of the compounds were elucidated using spectroscopic analysis. Among these isolated compounds, corilagin (3) was cytotoxic against human gastric adeno ...
DOI:
10.1007/s11418-021-01593-z

13. Two new ent-kaurane glucosides from the fruits of Xanthium strumarium subsp. sibiricum

Author:
Tie Yao; Jiaxin Wang; Shijie Cao; Da Liu; Jingshi Duan; Yaqin Yu; Ning Kang; Feng Qiu
Source:
Natural product research 2022 v.36 no.7 pp. 1820-1826
ISSN:
1478-6427
Subject:
X-ray diffraction; Xanthium strumarium; circular dichroism spectroscopy; glucosides; humans; neoplasm cells; research; spectral analysis
Abstract:
... The chemical investigation of the fruits of Xanthium strumarium (Asteraceae) led to the isolation of two new ent-kauranoid glucosides named 2-O-(6-O-isocaleryl-β-D-glucopyranosyl) atractyligenin (1) and 2-O-(2-O-isovaleryl-β-D-glucopyranosyl) atractyligenin (2), together with one known compound. Their structures were established by comprehensive spectroscopic analysis coupled with single-crystal X ...
DOI:
10.1080/14786419.2020.1819268

14. Two new phenolic glucosides from marine-derived fungus Aspergillus sp.

Author:
Huiling Wen; Yi Zang; Qianheng Zhu; Sheng Ouyang; Juanjuan Luo; Nianhua Luo; Hucheng Zhu; Yonghui Zhang
Source:
Natural product research 2022 v.36 no.13 pp. 3255-3261
ISSN:
1478-6427
Subject:
Aspergillus; acid hydrolysis; derivatization; electrospray ionization mass spectrometry; fungi; glucosides; macrophages; research; spectral analysis
Abstract:
... Two new phenolic glucosides, including a new O-glycoside (1) and a new C-glycoside (2), were isolated from a marine-derived fungus Aspergillus sp. The structures of new compounds were elucidated through interpretations of spectroscopic evidence and high-resolution electrospray ionization mass spectrometry. The hexose unit of 1 was identified as β-D-glucose by comparison with an authentic sample vi ...
DOI:
10.1080/14786419.2020.1851226

15. Two new stilbene glucosides and a new benzoic acid derivative from Tournefortia sibirica

Author:
Lan-Tian Cui; Zhe Jiang; Tie-Qiang Zong; Zheng-Yu Hu; Long Jin; Mei Jin; Jin-Feng Sun; Wei Zhou; Sheng-Bao Diao; Gao Li
Source:
Journal of Asian natural products research 2022 v.24 no.8 pp. 746-753
ISSN:
1477-2213
Subject:
Tournefortia; benzoic acid; glucosides; interleukin-6; research; spectral analysis; stilbenes
Abstract:
... Two new stilbene glucosides, trans-3,5-dihydroxy-4-methoxystilbene 3-O-β-D-glucopyranoside (1), cis-3,5-dihydroxy-4-methoxystilbene 3-O-β-D-glucopyranoside (2), one new benzoic acid derivative, cis-4-hydroxy-3-hydroxymethyl-2-butenyl benzoate 4-O-β-D-glucopyranoside (3), and four known compounds (4 − 7) were isolated from Tournefortia sibirica L. The structures of these compounds were elucidated o ...
DOI:
10.1080/10286020.2021.1983800

16. Anti-inflammatory new cyathane diterpene glucosides from Onychium japonicum

Author:
Ke Zan; Yongqiang Gan; Peide Xie; Ronglin Zhang; Shuangcheng Ma; Queyue Lin; Jian Zheng
Source:
Phytochemistry letters 2021 v.44 pp. 206-209
ISSN:
1874-3900
Subject:
Onychium; diterpenoids; glucosides; macrophages; moieties; nitric oxide; plant biochemistry; spectral analysis
Abstract:
... The chemical exploration of Onychium japonicum (Thunb.) O. Kuntze (Pteridaceae) aerial parts afforded two new cyathane diterpene glucosides (1 and 2). The structure elucidation of the new compounds was unambiguously performed based on HRESIMS and 1D and 2D NMR spectroscopic data analyses. These two compounds represent the first two cyathane diterpenes with a glucopyranosyl moiety. Compounds 1 and ...
DOI:
10.1016/j.phytol.2021.06.002

17. Antibacterial and antioxidant activities of compounds isolated from the leaves of Symphonia globulifera (Clusiaceae) and their chemophenetic significance

Author:
Dénis-Grégoire Téné; Anastasie Ewola Tih; Michael Hermann Kengne Kamdem; Rostan Mangoua Talla; Patrick Hervé Betote Diboue; Yanick Kevin Dongmo Melongo; Carelle Raïssa Dzukoug; Edwin Mpoh Mmutlane; Derek Tantoh Ndinteh; Bernard Bodo; Raphaël Tih Ghogomu
Source:
Biochemical systematics and ecology 2021 v.99 pp. 104345
ISSN:
0305-1978
Subject:
Symphonia globulifera; antioxidants; apigenin; chemotaxonomy; chromatography; cough; diabetes; ecology; epicatechin; fever; fractionation; glucosides; intestines; jaundice; luteolin; malaria; mass spectrometry; methanol; spectral analysis; stigmasterol; traditional medicine
Abstract:
... The phytochemical study was done on the methanol extract from of the leaves of Symphonia globulifera. This plant has been used in traditional medicine to treat of different ailments such as malaria, diseases of the skin, diabetes, cough, intestinal worms, pre-hepatic jaundice and fever. Chromatographic fractionation and purification of this extract led to the isolation and characterization of twel ...
DOI:
10.1016/j.bse.2021.104345

18. Chemical constituents of Mussaenda erythrophylla Schumach. & Thonn. (Rubiaceae) and their chemophenetic significance

Author:
Inest Larissa T. Bouzeko; Faustine Léonie M. Dongmo; Blanche Laure Ndontsa; Cyrille Armel N. Ngansop; Rodrigue Keumoe; Gabin Thierry M. Bitchagno; Jean Bosco Jouda; Roukayatou Mbouangouere; Billy Toussie Tchegnitegni; Fabrice Fekam Boyom; Norbert Sewald; Bruno Ndjakou Lenta; Pierre Tane; Silvère Augustin Ngouela; Mathieu Tene
Source:
Biochemical systematics and ecology 2021 v.98 pp. 104329
ISSN:
0305-1978
Subject:
Mussaenda; aerial parts; amphotericin B; antileishmanial properties; antiplasmodial properties; artemisinin; chemotaxonomy; coumarins; cytotoxicity; ecology; ethyl acetate; flavonoids; glucosides; hexane; polyols; quinic acid; spectral analysis; triterpenoids
Abstract:
... The chemical investigation of the CH₂Cl₂/MeOH (1:1) extract from the aerial part of Mussaenda erythrophylla Schumach. & Thonn. (Rubiaceae) resulted in the isolation of sixteen known compounds (1–16) distributed in coumarins, flavonoid glucosides, quinic acid derivatives, triterpenoids, monoglycerid, steroids, tetraterpenoid and polyol. The structures of the compounds were determined by spectrometr ...
DOI:
10.1016/j.bse.2021.104329

19. Improving Aqueous Solubility of Natural Antioxidant Mangiferin through Glycosylation by Maltogenic Amylase from Parageobacillus galactosidasius DSM 18751

Author:
Jiumn-Yih Wu; Hsiou-Yu Ding; Tzi-Yuan Wang; Yu-Li Tsai; Huei-Ju Ting; Te-Sheng Chang
Source:
Antioxidants 2021 v.10 no.11 pp. -
ISSN:
2076-3921
Subject:
2,2-diphenyl-1-picrylhydrazyl; Escherichia coli; Mangifera indica; affinity chromatography; amylases; flavonoids; free radicals; glucosides; glycosylation; high performance liquid chromatography; magnetism; mangoes; plasmids; polyphenols; saponins; solubility; spectral analysis; sugars; thermophiles; triterpenoids; xanthone
Abstract:
... Mangiferin is a natural antioxidant C-glucosidic xanthone originally isolated from the Mangifera indica (mango) plant. Mangiferin exhibits a wide range of pharmaceutical activities. However, mangiferin’s poor solubility limits its applications. To resolve this limitation of mangiferin, enzymatic glycosylation of mangiferin to produce more soluble mangiferin glucosides was evaluated. Herein, the re ...
DOI:
10.3390/antiox10111817

20. Inhibitory mechanism of O-methylated quercetins, highly potent β-secretase inhibitors isolated from Caragana balchaschensis (Kom.) Pojark

Author:
Kamila Zhumanova; Gihwan Lee; Aizhamal Baiseitova; Abdul Bari Shah; Jeong Ho Kim; Jeong Yoon Kim; Keun Woo Lee; Ki Hun Park
Source:
Journal of ethnopharmacology 2021 v.272 pp. 113935
ISSN:
0378-8741
Subject:
Alzheimer disease; Oriental traditional medicine; aerial parts; arthritis; blood circulation; enzymes; fluorescence; glucosides; hypertension; metabolites; migraine; quercetin; skeleton; spectral analysis
Abstract:
... Caragana has a standing history of implementation in Traditional Chinese Medicine (TCM). Most species of this genus have been explored for multi-functional purposes, such as promoting blood circulation and curing neuralgia, fatigue, migraine, arthritis, and vascular hypertension (Meng et al., 2009). Among them, the well-known species C. sinica showed the most promising potential to increase the ex ...
DOI:
10.1016/j.jep.2021.113935

21. Isolation and evaluation of virucidal activities of flavanone glycosides and rosmarinic acid derivatives from Dracocephalum spp. against feline calicivirus

Author:
Mirza Synthia Sabrin; Erdenechimeg Selenge; Yohei Takeda; Javzan Batkhuu; Haruko Ogawa; Dulamjav Jamsransuren; Keisuke Suganuma; Toshihiro Murata
Source:
Phytochemistry 2021 v.191 pp. 112896
ISSN:
0031-9422
Subject:
Dracocephalum; Feline calicivirus; Norovirus; flavanones; glucosides; humans; rosmarinic acid; spectral analysis
Abstract:
... Feline calicivirus is one of the surrogate viruses of human norovirus. This study aimed to identify virucidal compounds, chemical constituents of plants from the genus Dracocephalum, which are rich in flavonoids and phenylpropanoid oligomers. Four undescribed compounds, including a flavanone glucoside, two stilbenoid glycosides, and a phenylpropanoid amide glycoside, as well as 17 known compounds, ...
DOI:
10.1016/j.phytochem.2021.112896

22. Lignans with NO inhibitory activity from Tinospora sinensis

Author:
Jun-Sheng ZHANG; De-Feng XU; Xin-Xin CAO; Yin-Yin WANG; Hua ZHANG
Source:
Chinese journal of natural medicines 2021 v.19 no.7 pp. 500-504
ISSN:
1875-5364
Subject:
Tinospora sinensis; circular dichroism spectroscopy; density functional theory; glucosides; lignans; lipopolysaccharides; macrophages; mice; nitric oxide; spectral analysis
Abstract:
... Two new lignan glucosides, tinsinlignans A and B (1 and 2), two new oxyneolignans, tinsinlignans C and D (3 and 4), along with one known analogue (5), were isolated from the stems of Tinospora sinensis. The structures of the new compounds were elucidated based on analysis of spectroscopic data, and the absolute configuration of 1 was determined through electronic circular dichroism (ECD) calculati ...
DOI:
10.1016/S1875-5364(21)60049-3

23. New ent-kaurane-type diterpenoid with cytotoxic activity from Croton mekongensis

Author:
Kodchaniphar Udomthawee; Kittipong Chainok; Suwadee Jiajaroen; Narong Nuntasaen; Wilart Pompimon
Source:
Journal of Asian natural products research 2021 v.23 no.10 pp. 1001-1008
ISSN:
1477-2213
Subject:
Croton; X-ray diffraction; cytotoxicity; diterpenoids; glucosides; research; sitosterols; spectral analysis; spectroscopy
Abstract:
... A new ent-kaurane-type diterpenoid, crotonmekongenin A (1) together with two known compounds, epifriedelanol (2) and sitosterol glucoside (3) from the leaves and twigs of Croton mekongensis were isolated. The structure of these compounds was determined by spectroscopic analysis. The structure of the new ent-kaurane-type diterpenoid (1) was elucidated using spectroscopic technique and X-ray crystal ...
DOI:
10.1080/10286020.2020.1815714

24. Phenyl glycosides from the leaves of Flacourtia indica (Burm. f.) Merr (Salicaceae)

Author:
Phuc-Dam Nguyen; Charlotte Sayagh; Georges Massiot; Catherine Lavaud
Source:
Phytochemistry 2021 v.190 pp. 112891
ISSN:
0031-9422
Subject:
Flacourtia indica; cinnamic acid; glucose; glucosides; oxidation; phenol; plant biochemistry; spectral analysis
Abstract:
... Thirteen phenolic glycosides, together with fourteen various known compounds, were isolated from the methanolic extract of leaves of Flacourtia indica. Twelve of these were composed of gentisyl or salicyl alcohols, glycosylated on the phenol and acylated on the primary alcohol with various more or less oxidized forms of pyrocatechuic acid. A number of positions on the glucose or on the acid were f ...
DOI:
10.1016/j.phytochem.2021.112891

25. Phytochemical and chemotaxonomic study on the Lichen Lethariella cladonioides

Author:
Lei Zhang; Wei-Yun Di; Yu Hao; Li-Ning Wang; Yan-Ru Deng; Jing-Jing Wang
Source:
Biochemical systematics and ecology 2021 v.99 pp. 104343
ISSN:
0305-1978
Subject:
Parmeliaceae; alkanes; chemotaxonomy; dibenzofuran; ecology; fatty acids; glucosides; lichens; phenolic acids; phytochemicals; polyols; spectral analysis; China
Abstract:
... The comprehensive phytochemical research of Lethariella cladonioides (Nyl.) Krog, (Parmeliaceae), a lichen in southwest China, resulted in isolation of eighteen compounds (1–18), including a new phenolic acid 3,5-dihydroxy-4-methylbenzaldehyde (1) and seventeen known compounds, nine phenolic acids (2–10), one dibenzofuran (11), two depsides (12 and 13), one alkane (14), one glucoside (15), two pol ...
DOI:
10.1016/j.bse.2021.104343

26. Polyphenolics from Gymnocarpos decandrus Forssk roots and their biological activities

Author:
Hoda Fathy
Source:
Natural product research 2021 v.35 no.5 pp. 858-862
ISSN:
1478-6427
Subject:
Bacillus subtilis; Gymnocarpos; antimicrobial properties; coagulation; flavonoids; glucosides; polyphenols; prothrombin; research; root extracts; spectral analysis; thromboplastin
Abstract:
... Phytochemical investigation of Gymnocarpos decandrus roots lead to the isolation, characterization and evaluation of four compounds: the bis-coumarin daphnoretin, two biflavonoids: wikstrol A and wikstol B in addition to β-sitosterol glucoside. Their structures were established via spectroscopic data. The crude root extract showed a significant antimicrobial activity against Bacillus subtilis. In ...
DOI:
10.1080/14786419.2019.1607336

27. Two new rearranged clerodane diterpenes from Thai Tinospora baenzigeri

Author:
Sujitra Hanthanong; Siwattra Choodej; Thammarat Aree; Khanitha Pudhom
Source:
Natural medicines 2021 v.75 no.1 pp. 201-206
ISSN:
1340-3443
Subject:
Tinospora; X-ray diffraction; cytotoxicity; diterpenoids; glucosides; moieties; spectral analysis; tetrahydrofuran
Abstract:
... A new rearranged clerodane-type diterpene (1), tinobaenzigeride, and a new rearranged clerodane glucoside (2) were isolated from the stems of Tinospora baenzigeri, along with four known compounds (3‒6). Their structures were elucidated by spectroscopic data analysis. In addition, the structure and configuration of 1 was confirmed by single-crystal X-ray diffraction analysis. Compound 1 are a rare ...
DOI:
10.1007/s11418-020-01450-5

28. A new dammarane type triterpene glucoside from the aerial parts of Gouania longipetala (Rhamnaceae)

Author:
Soh Désiré; Nkwengoua Ernestine; Tchebemou Bakang Bruno; Sidjui Sidjui Lazare; Dzo Defokou Ulrich; Mehreen Lateef; Bernd Schneider; Muhammad Shaiq Ali; Nyassé Barthélemy
Source:
Natural product research 2021 v.35 no.19 pp. 3192-3203
ISSN:
1478-6427
Subject:
Gouania; antioxidant activity; glucosides; research; secondary metabolites; spectral analysis; triterpenoids; urease
Abstract:
... 3-O-β-D-glucopyranosyl gouanogenin A (1), a new naturally occurring dammarane class of triterpene glucoside, has been isolated from the aerial parts of Gouania longipetala along with six known secondary metabolites 2–7. Their structure was elucidated through spectroscopic data including 1 D- and 2 D-NMR. The compounds 1 and 6 showed significant antioxidant potential in DPPH radical scavenging assa ...
DOI:
10.1080/14786419.2019.1690483

29. Bambusicolasides VII and VIII, Two New Glucosides from the Bamboo Aphid Pseudoregma bambusicola

Author:
Puzhao Zhang; Shao Feng; Yamei Zhang
Source:
Chemistry of natural compounds 2020 v.56 no.5 pp. 817-820
ISSN:
0009-3130
Subject:
Aphidoidea; bamboos; chemistry; glucosides; spectral analysis
Abstract:
... Two new glucosides, bambusicolasides VII (1) and VIII (2), were isolated from the ethanolic extract of the bamboo aphid Pseudoregma bambusicola. The structures of the two glucosides were identified as 7-O-[2-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-2,5-dimethylchromone (1) and 1,3-di-(O-β-D-glucopyranosyl)-6-methyl-7-nitro-8-naphthol (2) on the basis of spectral data as well as chemical meth ...
DOI:
10.1007/s10600-020-03160-6

30. Bioactive Phytochemicals Isolated from Akebia quinata Enhances Glucose-Stimulated Insulin Secretion by Inducing PDX-1

Author:
Dahae Lee; Jin Su Lee; Jurdas Sezirahiga; Hak Cheol Kwon; Dae Sik Jang; Ki Sung Kang
Source:
Plants 2020 v.9 no.9 pp. -
ISSN:
2223-7747
Subject:
Akebia quinata; Western blotting; bioactive compounds; chemical structure; chocolate; duodenum; ethanol; fruits; glucosides; insulin receptor substrate proteins; insulin secretion; islets of Langerhans; mitogen-activated protein kinase; nuclear magnetic resonance spectroscopy; phosphatidylinositol 3-kinase; phytosterols; rats; saponins; spectral analysis; traditional medicine; triterpenoids; vines
Abstract:
... Chocolate vine (Akebia quinata) is consumed as a fruit and is also used in traditional medicine. In order to identify the bioactive components of A. quinata, a phytosterol glucoside stigmasterol-3-O-β-d-glucoside (1), three triterpenoids maslinic acid (2), scutellaric acid (3), and hederagenin (4), and three triterpenoidal saponins akebia saponin PA (5), hederacoside C (6), and hederacolchiside F ...
DOI:
10.3390/plants9091087

31. Bufadienolides from the whole plants of Helleborus foetidus and their cytotoxicity

Author:
Tomoki Iguchi; Akihito Yokosuka; Riko Kawahata; Madoka Andou; Yoshihiro Mimaki
Source:
Phytochemistry 2020 v.172 pp. 112277
ISSN:
0031-9422
Subject:
Helleborus foetidus; adenosinetriphosphatase; anticarcinogenic activity; apoptosis; bufadienolides; cytotoxicity; enzyme inhibition; glucosides; inhibitory concentration 50; sodium-potassium-exchanging ATPase; spectral analysis
Abstract:
... Two undescribed bufadienolide glucosides and four undescribed bufadienolides were isolated from the whole plants of Helleborus foetidus (Ranunculaceae). Their structures were determined by extensive spectroscopic analysis and the results of hydrolytic cleavage. The isolated compounds exhibited cytotoxic activities against HL-60 and A549 cells with IC₅₀ values ranging from 0.019 to 3.0 μM. The isol ...
DOI:
10.1016/j.phytochem.2020.112277

32. Chemical Constituents from the Whole Plant of Cuscuta reflexa

Author:
Tin Thu Thu Aung; Meng-Yuan Xia; Pyae Phyo Hein; Rong Tang; Dong-Dong Zhang; Jun Yang; Xue-Fei Yang; Dong-Bao Hu; Yue-Hu Wang
Source:
Natural products and bioprospecting 2020 v.10 no.5 pp. 337-344
ISSN:
2192-2195
Subject:
Cuscuta reflexa; anti-obesity effects; arachidonic acid; collagen; glucosides; platelet aggregation; platelet-activating factor; rabbits; spectral analysis; swine; thrombin; triacylglycerol lipase; Myanmar
Abstract:
... Two new 2H-pyran-2-one glucosides, cuscutarosides A (1) and B (2), and one new steroidal glucoside, 7β-methoxy-β-sitosterol 3-O-β-glucopyranoside (3), together with 12 known compounds (4–15) were isolated from the whole plant of Cuscuta reflexa (Convolvulaceae) collected from Myanmar. The chemical structures of these new compounds were elucidated based on extensive spectroscopic analysis. The anti ...
DOI:
10.1007/s13659-020-00265-x

33. Chemical Constituents of the Leaves of Campanula takesimana (Korean Bellflower) and Their Inhibitory Effects on LPS-induced PGE2 Production

Author:
Yutong Qi; Se-In Choi; So-Ri Son; Hee-Soo Han; Hye Shin Ahn; Yu-Kyong Shin; Sun Hee Lee; Kyung-Tae Lee; Hak Cheol Kwon; Dae Sik Jang
Source:
Plants 2020 v.9 no.9 pp. -
ISSN:
2223-7747
Subject:
Campanula takesimana; Oriental traditional medicine; anti-inflammatory activity; chemical composition; chromatography; ferulic acid; glucosides; herbal medicines; herbs; kaempferol; leaves; lignans; lipopolysaccharides; nuclear magnetic resonance spectroscopy; prostaglandins; quercetin; spectral analysis; Korean Peninsula
Abstract:
... Campanula takesimana Nakai (Campanulaceae; Korean bellflower) is one of the endemic herbs of Korea. The plant has been used as traditional medicines for treating asthma, tonsillitis, and sore throat in Korea. A hot water extract of the leaves of C. takesimana exhibited a significant inhibitory effect on lipopolysaccharide (LPS)-stimulated prostaglandin E₂ (PGE₂) production. Repetitive chromatograp ...
DOI:
10.3390/plants9091232

34. Chemical constituents from Ginkgo biloba leaves and their cytotoxicity activity

Author:
Penghua Shu; Mengyuan Sun; Junping Li; Lingxiang Zhang; Haichang Xu; Yueyue Lou; Zhiyu Ju; Xialan Wei; Wenming Wu; Na Sun
Source:
Natural medicines 2020 v.74 no.1 pp. 269-274
ISSN:
1340-3443
Subject:
Ginkgo biloba; chemical composition; cytotoxicity; ethanol; glucose; glucosides; human cell lines; leaves; methanolysis; spectral analysis
Abstract:
... One novel neoligan glucoside, Ginkgoside B (1), and one new glucose ester, 6-O-(4-hydroxyhydrocinnamoyl)-D-glucopyranose (2), along with nine known compounds (3–11) were isolated from the ethanol extract of Ginkgo biloba leaves. Their structures were elucidated by combination of spectroscopic analyses and alkaline methanolysis. The absolute configuration of compound 1 was determined by single-crys ...
DOI:
10.1007/s11418-019-01359-8

35. Chemical constituents from Phlomis bovei Noë and their chemotaxonomic significance

Author:
Walid Khitri; Dalila Smati; Anne-Claire Mitaine-Offer; Thomas Paululat; Marie-Aleth Lacaille-Dubois
Source:
Biochemical systematics and ecology 2020 v.91 pp. 104054
ISSN:
0305-1978
Subject:
Phlomis; carbon; chemical composition; chemotaxonomy; glucosides; iridoids; leaves; lignans; mass spectrometry; metabolites; norisoprenoids; nuclear magnetic resonance spectroscopy; phenylpropanoids; phytochemicals; roots; spectral analysis; stable isotopes
Abstract:
... A phytochemical investigation of the leaves and roots of Phlomis bovei Noë (Lamiaceae) led to the isolation of sixteen compounds, including iridoids (1, 2, 3), megastigmanes (4, 5), phenylpropanoids (6, 7, 8, 9, 10), lignans (11, 12, 13, 14), a nortriterpene (15), and a phenyl glucoside (16). Compounds (1, 2, 4, 5, 6, 10) were obtained from the leaves and compounds (1, 2, 3, 7, 8, 9, 11, 12, 13, 1 ...
DOI:
10.1016/j.bse.2020.104054

36. Chemical constituents from the bark of bauhinia purpurea and their NO inhibitory activities

Author:
Lin Ni; Wei Huang; Yan Shi; Heshan Wang; Yatie Qiu; Huiyou Xu
Source:
Natural product research 2020 v.34 no.17 pp. 2424-2429
ISSN:
1478-6427
Subject:
Bauhinia purpurea; X-ray diffraction; bark; chemical composition; chemical constituents of plants; glucosides; inhibitory concentration 50; macrophages; mice; nitric oxide; spectral analysis
Abstract:
... Phytochemical studies led to the isolation of a new phenylpropanoid glucoside, named purpuroside (1), along with eight known compounds (2–9) from the bark of Bauhinia purpurea. The structure of the new compound was elucidated on the basis of its spectroscopic data. The absolute configuration of compound 2 was verified by X-ray diffraction analysis. Compounds 1, 2, 7, 8, and 9 inhibited NO producti ...
DOI:
10.1080/14786419.2018.1543672

37. Chemical constituents from the fruits of Solanum incanum L

Author:
Joseph Sakah Kaunda; Ying-Jun Zhang
Source:
Biochemical systematics and ecology 2020 v.90 pp. 104031
ISSN:
0305-1978
Subject:
Solanum incanum; chemical composition; chemotaxonomy; coumarin; fruits; glucosides; glycoalkaloids; lignans; monoterpenoids; nuclear magnetic resonance spectroscopy; phytochemicals; spectral analysis
Abstract:
... Phytochemical investigation of the fruits of Solanum incanum L. resulted in the isolation of nine compounds, including three steroidal glycoalkaloids (1-3), two neolignans (4–5), two simple phenolics (6–7), one monoterpene glycoside (8), and one coumarin glucoside (9). The structure elucidation of isolated compounds was determined based on NMR and mass spectral data. Compounds 4 and 9 were isolate ...
DOI:
10.1016/j.bse.2020.104031

38. Diterpenoids caryopterisoids D - Q and iridoid glucoside derivatives caryopterisides F - H from Caryopteris glutinosa

Author:
Xuejian Zhang; Ting Peng; Xiaoke Shi; Dongmei Fang; Lin Tang; Fang Chen; Fei Wang; Guolin Zhang; Yinggang Luo
Source:
Phytochemistry 2020 v.180 pp. 112534
ISSN:
0031-9422
Subject:
Caryopteris; X-ray diffraction; assays; biosynthesis; data analysis; diterpenoids; estrogens; glucosides; plant biochemistry; spectral analysis
Abstract:
... Fourteen undescribed diterpenoids caryopterisoids D - Q, three undescribed iridoid glucoside derivatives caryopterisides F - H, and 8 known diterpenoids were isolated from the 95% aqueous ethanolic extract of Caryopteris glutinosa. Their structures were elucidated on the basis of spectroscopic data analysis and chemical derivation studies. The structure and absolute configuration of caryopterisoid ...
DOI:
10.1016/j.phytochem.2020.112534

39. Diverse bioactive metabolites from Penicillium sp. MMA derived from the red sea: structure identification and biological activity studies

Author:
Ann G. Boulis; Ahmed A. Hamed; Mohamed E. El-awady; Attia R. Mohamed; Essam M. Eliwa; Mohsen M. S. Asker; Mohamed Shaaban
Source:
Archives of microbiology 2020 v.202 no.7 pp. 1985-1996
ISSN:
0302-8933
Subject:
Penicillium; antioxidants; cerebrosides; computer simulation; cytotoxicity; drugs; ergosterol; fungi; glaucoma; glucosides; lead; linoleic acid; metabolites; molecular biology; sesquiterpenoids; spectral analysis; Red Sea
Abstract:
... A soft coral-derived fungus Penicillium sp. among other isolates e high antibacterial, anti-yeast and cytotoxic activities. The fungus, Penicillium sp. MMA, isolated from Sarcphyton glaucoma, afforded nine diverse compounds (1–9). Their structures were identified by 1D and 2 D NMR and ESI–MS spectroscopic data as two alkaloids: veridicatol (1), aurantiomide C (2); one sesquiterpene, aspterric acid ...
DOI:
10.1007/s00203-020-01923-x

40. Dratanguticumides G and H, two new glucosides from Dracocephalum tanguticum Maxim relax vessels via NO pathway

Author:
Li-Jiao Hu; Liang Zeng; En-Guang Ma; Cui Yang; Hai-Yan Wu; Gan-Peng Li
Source:
Phytochemistry letters 2020 v.40 pp. 42-48
ISSN:
1874-3900
Subject:
Dracocephalum tanguticum; Oriental traditional medicine; adverse effects; ethanol; glucosides; hypertension; incidence; morbidity; mortality; plant biochemistry; rats; spectral analysis; vasodilator agents; China
Abstract:
... Hypertension is one of the major sources of global incidence of cardiovascular diseases and one of the leading causes of global morbidity and mortality. It is necessary to search for natural products which have not adverse effects like many synthetic drugs as potential development agents for treating hypertension. Dracocephalum tanguticum Maxim, a perennial herb for Tibetan medicine in China, is w ...
DOI:
10.1016/j.phytol.2020.08.006

41. Linaburiosides A−D, acylated iridoid glucosides from Linaria buriatica

Author:
Kanji Niwa; Ren Yi; Naonobu Tanaka; Shindai Kitaguchi; Daisuke Tsuji; Sang-Yong Kim; Ariuntuya Tsogtbaatar; Perleidulam Bunddulam; Kazuyoshi Kawazoe; Mareshige Kojoma; Davaadagva Damdinjav; Kohji Itoh; Yoshiki Kashiwada
Source:
Phytochemistry 2020 v.171 pp. 112247
ISSN:
0031-9422
Subject:
Linaria; aerial parts; glucosides; herbal medicines; iridoid glycosides; moieties; spectral analysis
Abstract:
... Four previously undescribed acylated iridoid glucosides, linaburiosides A‒D, one undescribed iridoid, 7-deoxyiridolactonic acid, and one known acylated iridoid glucoside, iridolinarin C, were isolated from the aerial parts of a Mongolian traditional herbal medicine, Linaria buriatica. Linaburiosides A‒D had an acyl moiety corresponding to 7-deoxyiridolactonic acid. Detailed spectroscopic analyses ...
DOI:
10.1016/j.phytochem.2019.112247

42. New cucurbitane type triterpenes from Momordica foetida Schumach. (Cucurbitaceae)

Author:
Désiré Soh; Bruno Tchebemou Bakang; Ernestine Nkwengoua Tchouboun; Yves Oscar Ditchou Nganso; Ulrich Dzo Defokou; Lazare Sidjui Sidjui; Ayaz Ahmed; Rémy Bertrand Teponno; Mehreen Lateef; Muhammad Shaiq Ali; Barthélemy Nyassé
Source:
Phytochemistry letters 2020 v.38 pp. 90-95
ISSN:
1874-3900
Subject:
Momordica foetida; antioxidant activity; assays; cell lines; chemical constituents of plants; glucosides; mouth neoplasms; neoplasm cells; spectral analysis; triterpenoids; urease
Abstract:
... Phytochemical studies on Momordica foetida led to the isolation and characterization of Momordin (23,24,25,26,27-pentanorcucurbitacin) (3), a new pentanor cucurbitane along with the known β-sitosterol 3-O-β-D-glucopyranoside (4), β-sitosterol (5) and kaempferol-7-O-ß-D-glucopyranoside (6). In adition to those components, two previously unreported cucurbitane glucosides, namely 3β-hydroxy-7-oxo-23( ...
DOI:
10.1016/j.phytol.2020.05.010

43. New α-ditetralonyl glucoside from the green walnut husk of Juglans mandshurica

Author:
An-Dong Wang; Xin-Yu Xie; Wei-Ming Zeng; Jian-Yu Liu; Yong-Nan Xu
Source:
Natural product research 2020 v.34 no.21 pp. 3066-3072
ISSN:
1478-6427
Subject:
Juglans mandshurica; acid hydrolysis; cytotoxicity; glucosides; hulls; human cell lines; research; spectral analysis; walnuts
Abstract:
... One new α-ditetralonyl glucoside (1), was isolated from the green walnut husk of Juglans mandshurica (Juglandaceae), together with twelve known compounds (2–13). The structure of the new compound was determined as (2R,4S,10S,12S)-2-[7-(12,13,16-trihydroxy-α-tetralonyl-13-O-β-D-glucopyranoside)]- 4,8-dihydroxy-α-tetralone-4-O-β-D-glucopyranoside (1), on the basis of detailed spectroscopic analyses, ...
DOI:
10.1080/14786419.2019.1608538

44. Two new phenolic glycosides from the leaves of Garcinia epunctata Stapf

Author:
C. Emade Kwene; Anastasie E. Tih; Bintou Abderamane; Rapheal T. Ghogomu
Source:
Zeitschrift für Naturforschung 2020 v.75 no.1-2 pp. 51-56
ISSN:
1865-7125
Subject:
Garcinia; betulinic acid; glucosides; lupeol; secondary metabolites; spectral analysis; stigmasterol
Abstract:
... The leaves of Garcinia epunctata Stapf have furnished two new phenolic glucosides, epunctosides A and B, along with 13 known secondary metabolites identified as lanceoloside A, betulinic acid, lupeol, stigmasterol, β-sitosterol, β-sitosterol-3-O-β-d-glucopyranoside, stigmasterol-3-O-β-d-glucopyranoside, luteolin-7-O-glucoside, quercitin-7-O-glucoside, amentoflavone, robustaflavone, 4′-O-methyl-ame ...
DOI:
10.1515/znc-2018-0217

45. Vacillantins A and B, New Anthrone C-glycosides, and a New Dihydroisocoumarin Glucoside from Aloe vacillans and Its Antioxidant Activities

Author:
Maram Al-Tamimi; Shaza M. Al-Massarani; Ali A. El-Gamal; Omer A. Basudan; Maged S. Abdel-Kader; Wael M. Abdel-Mageed
Source:
Plants 2020 v.9 no.12 pp. -
ISSN:
2223-7747
Subject:
2,2-diphenyl-1-picrylhydrazyl; Aloe; anthraquinones; antioxidant activity; assays; butanol; drug therapy; extracts; free radical scavengers; glucosides; in vitro studies; isocoumarins; leaves; mass spectrometry; methylene chloride; nitric oxide; nuclear magnetic resonance spectroscopy; polyphenols; solvents; spectral analysis
Abstract:
... A new dihydroisocoumarin glucoside, vacillanoside (3), and two new anthrone C-glycosides microdantin derivatives; vacillantin A (10) and B (11), together with nine known compounds belonging to the anthraquinone, anthrone and isocoumarin groups were isolated from the leaves of Aloe vacillans. The structures were determined based on spectroscopic evidence including 1D and 2D nuclear magnetic resonan ...
DOI:
10.3390/plants9121632

46. Anti-inflammatory Ellagitannins from Cleidion brevipetiolatum for the Treatment of Rheumatoid Arthritis

Author:
Min Zhao; Xue Yuan; Ying-He Pei; Hao-Yu Ye; Ai-Hua Peng; Ming-Hai Tang; Da-Le Guo; Yun Deng; Li-Juan Chen
Source:
Journal of natural products 2019 v.82 no.9 pp. 2409-2418
ISSN:
1520-6025
Subject:
IKappaB kinase; cytosol; edema; gene expression; glucosides; inducible nitric oxide synthase; inhibitory concentration 50; medicinal plants; messenger RNA; models; nitric oxide; oral administration; phosphorylation; prostaglandin synthase; rats; rheumatoid arthritis; spectral analysis; transcription factor NF-kappa B
Abstract:
... Six new ellagitannins, brevipetins B–G (5 and 7–11), and a new phenolic glucoside, brevipetin A (4), along with six known compounds were isolated from the traditional Chinese medicinal plant Cleidion brevipetiolatum. Their structures and absolute configurations were determined by spectroscopic analyses, chemical methods, and TD-DFT-ECD calculations. Compounds 5–11 exhibited NO inhibitory effects w ...
DOI:
10.1021/acs.jnatprod.8b00984

47. Bioactive phenolic acid-substituted glycoses and glycosides from rhizomes of Cibotium barometz

Author:
Lan Li; Mei-Ping Xie; Hua Sun; An-Qi Lu; Bo Zhang; Dan Zhang; Su-Juan Wang
Source:
Journal of Asian natural products research 2019 v.21 no.10 pp. 947-953
ISSN:
1477-2213
Subject:
Cibotium barometz; acid hydrolysis; blood serum; cell death; glucosides; hepatoprotective effect; human cell lines; nuclear magnetic resonance spectroscopy; rhizomes; spectral analysis
Abstract:
... Two rarely phenolic acid-substituted alloses (1, 2) and one new glucoside (3), as well as nine known compounds (4–12) were isolated from rhizomes of Cibotium barometz (L.) J. Sm. Structures of 1–3 were established by extensively spectroscopic analyses (NMR, MS, etc.) and acid hydrolysis. All compounds were evaluated for the hepatoprotective activities against APAP-induced HepG2 cell damage. Compou ...
DOI:
10.1080/10286020.2018.1563076

48. Centaurea microcarpa Coss. & Dur. (Asteraceae) extracts: New cyanogenic glucoside and other constituents

Author:
Samia Baatouche; Thamere Cheriet; Djamel Sarri; Ratiba Mekkiou; Ouahiba Boumaza; Samir Benayache; Fadila Benayache; Ignacio Brouard; Francisco León; Ramdane Seghiri
Source:
Natural product research 2019 v.33 no.21 pp. 3070-3076
ISSN:
1478-6427
Subject:
Centaurea; beta-sitosterol; chloroform; electrospray ionization mass spectrometry; ethyl acetate; glucosides; nuclear magnetic resonance spectroscopy; prunasin; spectral analysis
Abstract:
... The phytochemical investigation of both chloroform and ethyl acetate extracts of Centaurea microcarpa Coss. & Dur. led to the isolation of a new cyanogenic glucoside 6'-methacrylate prunasin (3) together with seven known compounds: hydroxy-11β,13-dihydro onopordaldehyde (1), β-sitosterol (2), daucosterol (4), nepetin (5), prunasin (6), astragalin (7) and 7-O-β-D-glucopyranosyl centaureidin (8). Th ...
DOI:
10.1080/14786419.2018.1517343

49. Chemical constituents from the flowers of Satsuma mandarin and their free radical scavenging and α-glucosidase inhibitory activities

Author:
Anjana Adhikari-Devkota; Sara Mustafa Idris Elbashir; Takashi Watanabe; Hari Prasad Devkota
Source:
Natural product research 2019 v.33 no.11 pp. 1670-1673
ISSN:
1478-6427
Subject:
Citrus; alpha-glucosidase; antioxidant activity; chemical composition; enzyme inhibition; flowers; free radical scavengers; glucosides; hesperetin; hesperidin; methanol; nuclear magnetic resonance spectroscopy; quercetin; rutin; satsumas; sedatives; sleep disorders; spectral analysis; tea; traditional medicine; Japan
Abstract:
... Flowers of Citrus plants are used as mild sedatives and for the treatment of insomnia in traditional medicines. In Japan, tea made from the flowers of Satsuma mandarin is consumed as healthy drink. Hesperidin (1), hesperetin (2), rutin (3), quercetin (4), nicotiflorin (5), eriocitrin (6), narirutin (7), phenylethyl glucoside (8) and unshuoside A (9) were isolated from the MeOH extract of fresh flo ...
DOI:
10.1080/14786419.2018.1425856

50. Flavonoid glucosides from the flowers of Trollius chinensis Bunge

Author:
Rui Yan; Yida Cui; Bowen Deng; Jiayi Bi; Guogang Zhang
Source:
Natural medicines 2019 v.73 no.1 pp. 297-302
ISSN:
1340-3443
Subject:
Trollius chinensis; flavonoids; flowers; glucosides; spectral analysis
Abstract:
... Four new flavonoid glucosides, 2″-O-(6‴-O-caffeoyl)-galactopyranosylvitexin (1), 2″-O-(6‴-O-veratroyl)-galactopyranosylvitexin (2), 2″-O-(6‴-O-feruloyl)-galactopyranosylorientin (3), 2″-O-(2‴-O-methylbutyryl)-glucopyranosylisoswertisin (4), along with three known compounds were isolated from the flowers of Trollius chinensis Bunge. Their structures were determined by extensive spectroscopic analys ...
DOI:
10.1007/s11418-018-1263-1