U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject lignans Remove constraint Subject: lignans Subject term lignans Remove constraint Subject term: lignans Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
Start Over

Search

2,994  Search Results

« Previous | 1 - 20 of 2,994 |
Number of results to display per page

Search Results

1. Bioactive compounds of purslane (Portulaca oleracea L.) according to the production system: A review

Author:
César Omar Montoya-García; Rosario García-Mateos; Elvia Becerra-Martínez; Rocío Toledo-Aguilar; Víctor Hugo Volke-Haller; J. Jesús Magdaleno-Villar
Source:
Scientia horticulturae 2023 v.308 pp. 111584
ISSN:
0304-4238
Subject:
Philippines; Portulaca oleracea; abiotic stress; antioxidants; chemical composition; crop management; dietary supplements; flavonoids; glycosides; herbaceous plants; human health; hydroponics; lignans; metabolome; metabolomics; polysaccharides; sterols; terpenoids; Australia; Brazil; China; Greece; Iran; Italy; Malaysia; Mexico; Northern Africa; Spain; United Kingdom
Abstract:
... Purslane (Portulaca oleracea L.) is an herbaceous plant consumed in Italy, the United Kingdom, Spain, Greece, Turkey, Iran, Malaysia, the Philippines, China, North Africa, Australia, the United States, Brazil, and Mexico. Purslane contains nutraceutical compounds that can be potentiated based on biotic and abiotic stress practices. It provides substantial contributions of minerals, polysaccharides ...
DOI:
10.1016/j.scienta.2022.111584

2. Simulated gastrointestinal digestion/Caco-2 cell transport: Effects on biological activities and toxicity of a Brazilian propolis

Author:
Ana Sofia Martelli Chaib Saliba; Alan Giovanini de Oliveira Sartori; Pollyanna Souza Batista; José Eduardo Pedroso Gomes do Amaral; Namuhell Oliveira da Silva; Masaharu Ikegaki; Pedro Luiz Rosalen; Severino Matias de Alencar
Source:
Food chemistry 2023 v.403 pp. 134330
ISSN:
0308-8146
Subject:
Galleria mellonella; antimicrobial properties; chemical constituents of plants; chemokine CXCL2; digestion; digestive tract; food chemistry; food composition; functional foods; gastrointestinal system; human cell lines; interleukin-6; lethal dose; lignans; macrophages; phytochemicals; propolis; reactive oxygen species; transcription factors; Brazil
Abstract:
... The objective was to assess the effect of gastrointestinal digestion/Caco-2 cell transport on biological activities and toxicity of the ethanolic extract of organic propolis from southern Brazil (EEOP1). As principal results, the EEOP1 deactivated the ROO•, HOCl and O₂•⁻ reactive oxygen species, attenuated NF-κB transcription factor activation, and decreased the release of TNF-α and IL-6 in macrop ...
DOI:
10.1016/j.foodchem.2022.134330

3. Agrimonia pilosa Ledeb.: A review of its traditional uses, botany, phytochemistry, pharmacology, and toxicology

Author:
Sihua Wen; Xiaofei Zhang; Yanan Wu; Shangshang Yu; Wei Zhang; Ding Liu; Kai Yang; Jing Sun
Source:
Heliyon 2022 v.8 no.8 pp. e09972
ISSN:
2405-8440
Subject:
Agrimonia pilosa; Internet; Japan; Oriental traditional medicine; antioxidants; calcium oxide; dysentery; enteritis; flavonoids; gastrointestinal system; grasses; herbal medicines; isocoumarins; lignans; malaria; pharmacokinetics; toxicology; triterpenoids; China; Korean Peninsula
Abstract:
... Agrimonia pilosa Ledeb. is the dried above-ground part of dragon's tooth grass, a plant of the Rosaceae family, which is widely distributed in China, Korea, and Japan. Agrimonia pilosa Ledeb. is a herbal medicine with great scope for development and use. It is astringent and hemostatic, and it is used for treating malaria, preventing dysentery, detoxification, and as a tonic for deficiency. We sum ...
DOI:
10.1016/j.heliyon.2022.e09972

4. Alleviation of cognitive deficits via upregulation of chondroitin sulfate biosynthesis by lignan sesamin in a mouse model of neuroinflammation

Author:
Jun Yamada; Shoichiro Maeda; Mariko Soya; Hidefumi Nishida; Kyoko M. Iinuma; Shozo Jinno
Source:
Journal of nutritional biochemistry 2022 v.108 pp. 109093
ISSN:
0955-2863
Subject:
Wisteria floribunda; adults; agglutinins; biosynthesis; chondroitin sulfate; cognition; estrogens; extracellular matrix; hippocampus; lignans; lipopolysaccharides; locomotion; memory; mice; neurogenesis; proteoglycans
Abstract:
... Lignans are plant-derived compounds that act as partial estrogen agonists. Chondroitin sulfate proteoglycans (CSPGs) represent one of the major components of the extracellular matrix. Here we aimed to understand the role of sesamin (SES), a major lignan compound, in the biosynthesis and degradation of CSPGs in the mouse hippocampus because CSPGs play a key role in the regulation of cognitive funct ...
DOI:
10.1016/j.jnutbio.2022.109093

5. Anti-Inflammatory Phytoconstituents of Origanum Majorana

Author:
Li Zhou; Senye Wang; Jiaojiao Qu; Huihui Zhou; Al-Zahra K. K. Attia Fatma; Wenyi Kang; Xuefeng Xi; Zhenhua Liu
Source:
Journal of food quality 2022 v.2022 pp. -
ISSN:
1745-4557
Subject:
Origanum majorana; arthritis; asthma; chemical constituents of plants; ethanol; fever; flavonoids; food quality; glycosides; hypertension; influenza; lignans; migraine; spices; Egypt
Abstract:
... Origanum majorana belongs to the Lamiaceae family as a famous spice plant in Egypt, which is used to treat arthritis, allergies, fever, flu, hypertension, respiratory infections, migraine, and asthma. In our studies, it was found that the ethanol extract of O. marjoram could significantly reduce NO release at 200 (P<0.001), 100 (P<0.001) and 50 (P<0.01) μg/mL compared with the model group. Therefo ...
DOI:
10.1155/2022/3888075

6. Anti-hypoxic active constituents from the twigs of Zanthoxylum armatum DC. and their chemotaxonomic significance

Author:
Xiao-Xue Zhai; Xian-Hua Meng; Cheng-Bo Wang; Ya-Min Zhao; Jun-Li Yang
Source:
Biochemical systematics and ecology 2022 v.104 pp. 104480
ISSN:
0305-1978
Subject:
Zanthoxylum armatum; chemotaxonomy; ecology; lignans; phytochemicals; spectral analysis
Abstract:
... Phytochemical investigation of the twigs of Zanthoxylum armatum DC. led to the extraction and isolation of twenty-one compounds, including nine phenolic acids (1–9), a steroid (10) and eleven lignans (11–21). The structures of these compounds were elucidated by NMR spectroscopic analysis, and comparison with the reported data. Compounds 1–7, 15, 17, 18, and 21 were first obtained from Z. armatum. ...
DOI:
10.1016/j.bse.2022.104480

7. Anti-inflammatory and cytotoxic specialised metabolites from the leaves of Glandularia × hybrida

Author:
Nesma M. Mohamed; Mai A.M. Ahmed; Shabana I. Khan; Frank R. Fronczek; Anber F. Mohammed; Samir A. Ross
Source:
Phytochemistry 2022 v.195 pp. 113054
ISSN:
0031-9422
Subject:
Glandularia; computer simulation; cytotoxicity; lignans; metabolites; pharmacokinetics; phytochemicals; triterpenoid saponins
Abstract:
... In our ongoing effort to investigate active specialised metabolites from genus Glandularia, phytochemical studies on the ethanolic extract of Glandularia × hybrida (Groenl. & Rümpler) G.L. Nesom & Pruski leaves resulted in the isolation of three undescribed compounds, a dibenzylbutyrolactolic lignan and two echinocystic acid based triterpenoid saponins, in addition to two known compounds. Interest ...
DOI:
10.1016/j.phytochem.2021.113054

8. Antioxidant lignans sesamin and sesamolin in sesame (Sesamumindicum L.): a comprehensive review and future prospects

Author:
Senouwa Segla Koffi Dossou; Fang-tao XU; Komivi Dossa; Rong ZHOU; Ying-zhong ZHAO; Lin-hai WANG
Source:
Journal of integrative agriculture 2022 pp. -
ISSN:
2095-3119
Subject:
Sesamum indicum; agriculture; antioxidants; biosynthesis; cash crops; cultivars; germplasm; imports; lignans; oils; oilseed crops
Abstract:
... Sesame (Sesamum indicum L.) is a significantly lucrative cash crop for millions of small-holder farmers. Its seeds are an important source of a world highly appreciated oil and two clinically essential antioxidant lignans, sesamin and sesamolin. Accordingly, many countries import annually millions of tons of sesame seeds. The demand for lignan-rich sesame seeds is increasing yearly due to the cont ...
DOI:
10.1016/j.jia.2022.08.097

9. Antiviral and Antioxidant Components from the Fruits of Illicium verum Hook.f. (Chinese Star Anise)

Author:
Wen Li; Zhongnan Wu; Yiping Xia; Jinlin Tan; Haiyue Zhao; Si Chen; Yaolan Li; Hongfeng Tang; Guocai Wang; Yubo Zhang
Source:
Journal of agricultural and food chemistry 2022 v.70 no.12 pp. 3697-3707
ISSN:
1520-5118
Subject:
Illicium verum; Orthomyxoviridae; anise; antioxidants; antiviral properties; circular dichroism spectroscopy; cuisine; cytopathogenicity; electrospray ionization mass spectrometry; fluorescent antibody technique; food chemistry; fruits; lignans; oseltamivir; phenylpropanoids; phytochemicals; spectral analysis; South East Asia
Abstract:
... Illicium verum Hook.f. (Chinese star anise), a known Chinese traditional spice, is commonly applied in Chinese cuisine and cooking in Southeast Asia. As a kind of medicinal and edible resource, the fruit of I. verum has attracted great attention for its chemical constituents and physiological activities. In this work, the phytochemical study of the fruits of I. verum led to the isolation and ident ...
DOI:
10.1021/acs.jafc.1c08376

10. Bioactive neolignans and lignans from the roots of Paeonia lactiflora

Author:
Huan XIA; Jing-Fang ZHANG; Ling-Yan WANG; Gui-Yang XIA; Ya-Nan WANG; Yu-Zhuo WU; Peng-Cheng LIN; Liang XIONG; Sheng LIN
Source:
Chinese journal of natural medicines 2022 v.20 no.3 pp. 210-214
ISSN:
1875-5364
Subject:
Paeonia lactiflora; X-ray diffraction; carboxylesterase; circular dichroism spectroscopy; enantiomers; humans; lignans; spectral analysis
Abstract:
... Two new neolignans and one new lignan (1–3) were obtained from the roots of Paeonia lactiflora. Their structures were unambiguously elucidated based on extensive spectroscopic analysis, single-crystal X-ray crystallography, and the calculated and experimental electronic circular dichroism (ECD) spectra. Compound 1 was a racemic mixture and successfully resolved into the anticipated enantiomers via ...
DOI:
10.1016/S1875-5364(22)60164-X

11. Bis-iridoids and other constituents from Scabiosa semipapposa

Author:
Samia Bendamene; Naima Boutaghane; Charlotte Sayagh; Abdulmagid Alabdul Magid; Zahia Kabouche; Chawki Bensouici; Laurence Voutquenne-Nazabadioko
Source:
Phytochemistry letters 2022 v.49 pp. 202-210
ISSN:
1874-3900
Subject:
Scabiosa; antioxidant activity; antioxidants; chemotaxonomy; flavonoids; glycosides; iridoids; lignans; mass spectrometry; phenol; spectral analysis
Abstract:
... Six undescribed bis-iridoids named Semipapposiridoids A–F (1–6) together with seventeen known compounds were obtained from the roots and aerial parts of Scabiosa semipapposa Salzm. ex DC. Among the known compounds, three lignans were isolated for the first time in Scabiosa species, whereas the other known constituents including iridoids, phenol glycosides and flavonoids were previously isolated fr ...
DOI:
10.1016/j.phytol.2022.04.005

12. Breeding history for shattering trait in sesame: classic to genomic approach

Author:
Moin Qureshi; D. Ray Langham; Stuart J. Lucas; Bulent Uzun; Engin Yol
Source:
Molecular biology reports 2022 v.49 no.7 pp. 7185-7194
ISSN:
0301-4851
Subject:
CRISPR-Cas systems; RNA interference; antioxidants; genes; genomics; lignans; mechanical harvesting; mechanization; molecular biology; mutagenesis; nucleases; oils; oilseed crops; protein content; zinc finger motif
Abstract:
... Sesame is an important oilseed crop that has high oil and protein content and unique antioxidant lignans. Capsule shattering at harvest is one of the most important problems affecting sesame production, with seed losses of up to 50%, making the crop unsuitable for mechanized harvesting. This paper provides an overview of breeding approaches addressing the capsule shattering trait in sesame and giv ...
DOI:
10.1007/s11033-022-07636-2

13. Caucasian Dragonheads: Phenolic Compounds, Polysaccharides, and Bioactivity of Dracocephalum austriacum and Dracocephalum botryoides

Author:
Nina I. Kashchenko; Gunay S. Jafarova; Javanshir I. Isaev; Daniil N. Olennikov; Nadezhda K. Chirikova
Source:
Plants 2022 v.11 no.16 pp. -
ISSN:
2223-7747
Subject:
Dracocephalum; antioxidant activity; arabinogalactan proteins; benzoic acid; chemical composition; cuisine; flavonoids; lignans; liquid chromatography; mass spectrometry; metabolites; methanol; phenylpropanoids; polysaccharides; traditional medicine; water solubility; Caucasus region
Abstract:
... Dracocephalum botryoides Steven and Dracocephalum austriacum L. are unexplored species of the Dracocephalum genus (Lamiaceae family) with a distribution in the Caucasus, where they are used in folk medicine and local cuisine. There are no data on the chemical composition of these Dracocephalum species. In this study, the application of a liquid chromatography-mass spectrometry technique for the me ...
DOI:
10.3390/plants11162126

14. Characterization of chemical constituents in Shuanghuanglian oral dosage forms by ultra‐high performance liquid chromatography coupled with time‐of‐flight mass spectrometry

Author:
Ruiyun Li; Yanru Zhu; Mingyan Ma; Min Lei; Yingchun Zhao; Ting Liu; Miao Yu; Yunli Zhao; Zhiguo Yu
Source:
Journal of separation science 2022 v.45 no.5 pp. 1020-1030
ISSN:
1615-9306
Subject:
Oriental traditional medicine; anthraquinones; caffeic acid; coumarins; flavonoids; iridoids; lignans; mass spectrometry; oral administration; separation; triterpenoids; ultra-performance liquid chromatography
Abstract:
... Shuanghuanglian is a common traditional Chinese medicine prescription. It is an herbal formula composed of Lonicerae Japonicae Flos, Scutellariae Radix, and Forsythiae Fructus. A comprehensive understanding of Shuanghuanglian oral dosage forms components was obtained using a method based on ultra‐high performance liquid chromatography coupled with time‐of‐flight mass spectrometry for the separatio ...
DOI:
10.1002/jssc.202100860

15. Characterization of chemical constituents with their antioxidant and anti-melanogenesis activities from the roots of Ampelopsis japonica

Author:
Chia-Lin Lee; Yun-Lian Jhan; Hsiu-Mei Chiang; Yi-Hung Chen; Chao-Jung Chen; Yuan-Shiun Chang
Source:
Natural product research 2022 v.36 no.12 pp. 3133-3137
ISSN:
1478-6427
Subject:
Ampelopsis; anthraquinones; cosmetics; free radicals; glycosylation; keratinocytes; lignans; melanin; melanoma; research; stilbenes
Abstract:
... Three glycosylated stilbenes (1–3), two anthraquinones (4, 5), one lignan (6), five tannins (7–11), two amino acids (12, 13), and one auronol (14) were isolated from the root of Ampelopsis japonica. All compounds, except for 4, 6, and 11 were obtained from this species for the first time. Compounds 6–9 could notably inhibit ROS generations in HaCaT keratinocyte cells with IC₅₀ values of 5.28, 4.83 ...
DOI:
10.1080/14786419.2021.1939335

16. Characterization, expression, and functional analysis of the pathogenesis-related gene PtDIR11 in transgenic poplar

Author:
Lingling Li; Weibo Sun; Pu Wang; Hongyan Li; Shamsur Rehman; Dawei Li; Qiang Zhuge
Source:
International journal of biological macromolecules 2022 v.210 pp. 182-195
ISSN:
0141-8130
Subject:
Populus trichocarpa; biosynthesis; cell membranes; coniferyl alcohol; disease resistance; ethylene; flavonoids; genes; immunity; jasmonic acid; lignans; lignin; lignin content; methanol; pathogenesis-related proteins; quantitative polymerase chain reaction; reverse transcription; salicylic acid; signal transduction
Abstract:
... Lignins and lignans are important for plant resistance to pathogens. Dirigent (DIR) proteins control the regio- and stereo-selectivity of coniferyl alcohol in lignan and lignin biosynthesis. DIR genes have been implicated in defense-related responses in several plant species, but their role in poplar immunity is unclear. We cloned PtDIR11 from Populus trichocarpa; we found that overexpression of P ...
DOI:
10.1016/j.ijbiomac.2022.05.012

17. Chemical and biological studies of Daphniphyllum oldhamii from Hunan Province, China

Author:
Yi Chen; Shou-Mao Shen; Min Yang; Ming-Zhi Su; Xiao-Ming Wang; Yue-Wei Guo
Source:
Phytochemistry 2022 v.199 pp. 113170
ISSN:
0031-9422
Subject:
Daphniphyllum; X-ray diffraction; lignans; plant biochemistry; spectral analysis; triterpenoids; China
Abstract:
... The fruits, twigs and leaves of Daphniphyllum oldhamii (Hemsl.) K. Rosenthal, collected from Longshan County, Hunan Province, China, were chemically investigated. Three undescribed daphniphyllum alkaloids, namely longshanoldhamines A‒C, and six known related ones have been isolated from the fruits, whereas two undescribed triterpenoids and one undescribed lignan, along with six known triterpenoids ...
DOI:
10.1016/j.phytochem.2022.113170

18. Chemical constituents and their antioxidant and anti-inflammatory activities from edible Cornus officinalis fruits

Author:
Zhongcan Peng; Yuming Wang; Jun He; Jia Zhang; Xuege Pan; Xiansheng Ye; Weiku Zhang; Jiekun Xu
Source:
European food research & technology 2022 v.248 no.4 pp. 1003-1010
ISSN:
1438-2377
Subject:
2,2-diphenyl-1-picrylhydrazyl; Cornus officinalis; acid hydrolysis; cell lines; electrospray ionization mass spectrometry; food production; food research; functional foods; inflammation; interleukin-6; lignans; lipopolysaccharides; macrophages; nitric oxide; phytochemicals; technology; traditional medicine
Abstract:
... Cornus officinalis fruits, an edible functional food with the tonic effect, belongs to the Cornaceae family. It is widely used in both traditional medicine and in some food production. A phytochemical study on the fruits of Cornus officinalis resulted in 20 structurally diverse compounds including 2 new lignans, named officinalignans A-B (1–2), and 2 new iridoids, named loganin-(4′-O-7″)-α-morroni ...
DOI:
10.1007/s00217-021-03940-6

19. Chemical constituents from Dracocephalum moldavica L. and their chemotaxonomic significance

Author:
Jiaming Wang; Jinfeng Sun; Mengjie Wang; Huiqiong Cui; Wei Zhou; Gao Li
Source:
Biochemical systematics and ecology 2022 v.102 pp. 104422
ISSN:
0305-1978
Subject:
Dracocephalum moldavica; chemotaxonomy; ecology; glycosides; lignans; monoterpenoids; norisoprenoids; phytochemicals; spectral analysis; triterpenoids
Abstract:
... A phytochemical investigation of the aerial parts of Dracocephalum moldavica L. (Lamiaceae) led to the isolation and characterization of 30 compounds, including eight lignans (1–8), seven phenols (9–15), five triterpenoids (16–20), four monoterpenoids (21–24), four glycosides (25–28) and two megastigmanes (29 and 30). The structures of these compounds were determined by spectroscopic data analysis ...
DOI:
10.1016/j.bse.2022.104422

20. Chemical constituents from Maytenus hookeri

Author:
Nian Jiang; Changyan Yu; Jing Hui; Jianxun Xie; Yuanyuan Wang; Jun Yang; Sanhua Li; Lingjie Meng
Source:
Biochemical systematics and ecology 2022 v.104 pp. 104475
ISSN:
0305-1978
Subject:
Maytenus; chemotaxonomy; ecology; lignans; phenylpropanoids; phytochemicals; saponins; spectral analysis; triterpenoids
Abstract:
... A phytochemical investigation on the branches of Maytenus hookeri resulted in the isolation and identification of fourteen compounds, including one new triterpene saponin (1), five phenylpropanoids (2–6), and eight lignans (7–14). The chemical structures of these compounds were determined by comprehensive spectroscopic data analysis, such as UV, IR, 1D/2D NMR, mass spectra, and data from the liter ...
DOI:
10.1016/j.bse.2022.104475