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1. Bioactive compounds of purslane (Portulaca oleracea L.) according to the production system: A review

Author:
César Omar Montoya-García; Rosario García-Mateos; Elvia Becerra-Martínez; Rocío Toledo-Aguilar; Víctor Hugo Volke-Haller; J. Jesús Magdaleno-Villar
Source:
Scientia horticulturae 2023 v.308 pp. 111584
ISSN:
0304-4238
Subject:
Philippines; Portulaca oleracea; abiotic stress; antioxidants; chemical composition; crop management; dietary supplements; flavonoids; glycosides; herbaceous plants; human health; hydroponics; lignans; metabolome; metabolomics; polysaccharides; sterols; terpenoids; Australia; Brazil; China; Greece; Iran; Italy; Malaysia; Mexico; Northern Africa; Spain; United Kingdom
Abstract:
... Purslane (Portulaca oleracea L.) is an herbaceous plant consumed in Italy, the United Kingdom, Spain, Greece, Turkey, Iran, Malaysia, the Philippines, China, North Africa, Australia, the United States, Brazil, and Mexico. Purslane contains nutraceutical compounds that can be potentiated based on biotic and abiotic stress practices. It provides substantial contributions of minerals, polysaccharides ...
DOI:
10.1016/j.scienta.2022.111584

2. Simulated gastrointestinal digestion/Caco-2 cell transport: Effects on biological activities and toxicity of a Brazilian propolis

Author:
Ana Sofia Martelli Chaib Saliba; Alan Giovanini de Oliveira Sartori; Pollyanna Souza Batista; José Eduardo Pedroso Gomes do Amaral; Namuhell Oliveira da Silva; Masaharu Ikegaki; Pedro Luiz Rosalen; Severino Matias de Alencar
Source:
Food chemistry 2023 v.403 pp. 134330
ISSN:
0308-8146
Subject:
Galleria mellonella; antimicrobial properties; chemical constituents of plants; chemokine CXCL2; digestion; digestive tract; food chemistry; food composition; functional foods; gastrointestinal system; human cell lines; interleukin-6; lethal dose; lignans; macrophages; phytochemicals; propolis; reactive oxygen species; transcription factors; Brazil
Abstract:
... The objective was to assess the effect of gastrointestinal digestion/Caco-2 cell transport on biological activities and toxicity of the ethanolic extract of organic propolis from southern Brazil (EEOP1). As principal results, the EEOP1 deactivated the ROO•, HOCl and O₂•⁻ reactive oxygen species, attenuated NF-κB transcription factor activation, and decreased the release of TNF-α and IL-6 in macrop ...
DOI:
10.1016/j.foodchem.2022.134330

3. Agrimonia pilosa Ledeb.: A review of its traditional uses, botany, phytochemistry, pharmacology, and toxicology

Author:
Sihua Wen; Xiaofei Zhang; Yanan Wu; Shangshang Yu; Wei Zhang; Ding Liu; Kai Yang; Jing Sun
Source:
Heliyon 2022 v.8 no.8 pp. e09972
ISSN:
2405-8440
Subject:
Agrimonia pilosa; Internet; Japan; Oriental traditional medicine; antioxidants; calcium oxide; dysentery; enteritis; flavonoids; gastrointestinal system; grasses; herbal medicines; isocoumarins; lignans; malaria; pharmacokinetics; toxicology; triterpenoids; China; Korean Peninsula
Abstract:
... Agrimonia pilosa Ledeb. is the dried above-ground part of dragon's tooth grass, a plant of the Rosaceae family, which is widely distributed in China, Korea, and Japan. Agrimonia pilosa Ledeb. is a herbal medicine with great scope for development and use. It is astringent and hemostatic, and it is used for treating malaria, preventing dysentery, detoxification, and as a tonic for deficiency. We sum ...
DOI:
10.1016/j.heliyon.2022.e09972

4. Alleviation of cognitive deficits via upregulation of chondroitin sulfate biosynthesis by lignan sesamin in a mouse model of neuroinflammation

Author:
Jun Yamada; Shoichiro Maeda; Mariko Soya; Hidefumi Nishida; Kyoko M. Iinuma; Shozo Jinno
Source:
Journal of nutritional biochemistry 2022 v.108 pp. 109093
ISSN:
0955-2863
Subject:
Wisteria floribunda; adults; agglutinins; biosynthesis; chondroitin sulfate; cognition; estrogens; extracellular matrix; hippocampus; lignans; lipopolysaccharides; locomotion; memory; mice; neurogenesis; proteoglycans
Abstract:
... Lignans are plant-derived compounds that act as partial estrogen agonists. Chondroitin sulfate proteoglycans (CSPGs) represent one of the major components of the extracellular matrix. Here we aimed to understand the role of sesamin (SES), a major lignan compound, in the biosynthesis and degradation of CSPGs in the mouse hippocampus because CSPGs play a key role in the regulation of cognitive funct ...
DOI:
10.1016/j.jnutbio.2022.109093

5. Anti-Inflammatory Phytoconstituents of Origanum Majorana

Author:
Li Zhou; Senye Wang; Jiaojiao Qu; Huihui Zhou; Al-Zahra K. K. Attia Fatma; Wenyi Kang; Xuefeng Xi; Zhenhua Liu
Source:
Journal of food quality 2022 v.2022 pp. -
ISSN:
1745-4557
Subject:
Origanum majorana; arthritis; asthma; chemical constituents of plants; ethanol; fever; flavonoids; food quality; glycosides; hypertension; influenza; lignans; migraine; spices; Egypt
Abstract:
... Origanum majorana belongs to the Lamiaceae family as a famous spice plant in Egypt, which is used to treat arthritis, allergies, fever, flu, hypertension, respiratory infections, migraine, and asthma. In our studies, it was found that the ethanol extract of O. marjoram could significantly reduce NO release at 200 (P<0.001), 100 (P<0.001) and 50 (P<0.01) μg/mL compared with the model group. Therefo ...
DOI:
10.1155/2022/3888075

6. Anti-hypoxic active constituents from the twigs of Zanthoxylum armatum DC. and their chemotaxonomic significance

Author:
Xiao-Xue Zhai; Xian-Hua Meng; Cheng-Bo Wang; Ya-Min Zhao; Jun-Li Yang
Source:
Biochemical systematics and ecology 2022 v.104 pp. 104480
ISSN:
0305-1978
Subject:
Zanthoxylum armatum; chemotaxonomy; ecology; lignans; phytochemicals; spectral analysis
Abstract:
... Phytochemical investigation of the twigs of Zanthoxylum armatum DC. led to the extraction and isolation of twenty-one compounds, including nine phenolic acids (1–9), a steroid (10) and eleven lignans (11–21). The structures of these compounds were elucidated by NMR spectroscopic analysis, and comparison with the reported data. Compounds 1–7, 15, 17, 18, and 21 were first obtained from Z. armatum. ...
DOI:
10.1016/j.bse.2022.104480

7. Anti-inflammatory and cytotoxic specialised metabolites from the leaves of Glandularia × hybrida

Author:
Nesma M. Mohamed; Mai A.M. Ahmed; Shabana I. Khan; Frank R. Fronczek; Anber F. Mohammed; Samir A. Ross
Source:
Phytochemistry 2022 v.195 pp. 113054
ISSN:
0031-9422
Subject:
Glandularia; computer simulation; cytotoxicity; lignans; metabolites; pharmacokinetics; phytochemicals; triterpenoid saponins
Abstract:
... In our ongoing effort to investigate active specialised metabolites from genus Glandularia, phytochemical studies on the ethanolic extract of Glandularia × hybrida (Groenl. & Rümpler) G.L. Nesom & Pruski leaves resulted in the isolation of three undescribed compounds, a dibenzylbutyrolactolic lignan and two echinocystic acid based triterpenoid saponins, in addition to two known compounds. Interest ...
DOI:
10.1016/j.phytochem.2021.113054

8. Antioxidant lignans sesamin and sesamolin in sesame (Sesamumindicum L.): a comprehensive review and future prospects

Author:
Senouwa Segla Koffi Dossou; Fang-tao XU; Komivi Dossa; Rong ZHOU; Ying-zhong ZHAO; Lin-hai WANG
Source:
Journal of integrative agriculture 2022 pp. -
ISSN:
2095-3119
Subject:
Sesamum indicum; agriculture; antioxidants; biosynthesis; cash crops; cultivars; germplasm; imports; lignans; oils; oilseed crops
Abstract:
... Sesame (Sesamum indicum L.) is a significantly lucrative cash crop for millions of small-holder farmers. Its seeds are an important source of a world highly appreciated oil and two clinically essential antioxidant lignans, sesamin and sesamolin. Accordingly, many countries import annually millions of tons of sesame seeds. The demand for lignan-rich sesame seeds is increasing yearly due to the cont ...
DOI:
10.1016/j.jia.2022.08.097

9. Antiviral and Antioxidant Components from the Fruits of Illicium verum Hook.f. (Chinese Star Anise)

Author:
Wen Li; Zhongnan Wu; Yiping Xia; Jinlin Tan; Haiyue Zhao; Si Chen; Yaolan Li; Hongfeng Tang; Guocai Wang; Yubo Zhang
Source:
Journal of agricultural and food chemistry 2022 v.70 no.12 pp. 3697-3707
ISSN:
1520-5118
Subject:
Illicium verum; Orthomyxoviridae; anise; antioxidants; antiviral properties; circular dichroism spectroscopy; cuisine; cytopathogenicity; electrospray ionization mass spectrometry; fluorescent antibody technique; food chemistry; fruits; lignans; oseltamivir; phenylpropanoids; phytochemicals; spectral analysis; South East Asia
Abstract:
... Illicium verum Hook.f. (Chinese star anise), a known Chinese traditional spice, is commonly applied in Chinese cuisine and cooking in Southeast Asia. As a kind of medicinal and edible resource, the fruit of I. verum has attracted great attention for its chemical constituents and physiological activities. In this work, the phytochemical study of the fruits of I. verum led to the isolation and ident ...
DOI:
10.1021/acs.jafc.1c08376

10. Bioactive neolignans and lignans from the roots of Paeonia lactiflora

Author:
Huan XIA; Jing-Fang ZHANG; Ling-Yan WANG; Gui-Yang XIA; Ya-Nan WANG; Yu-Zhuo WU; Peng-Cheng LIN; Liang XIONG; Sheng LIN
Source:
Chinese journal of natural medicines 2022 v.20 no.3 pp. 210-214
ISSN:
1875-5364
Subject:
Paeonia lactiflora; X-ray diffraction; carboxylesterase; circular dichroism spectroscopy; enantiomers; humans; lignans; spectral analysis
Abstract:
... Two new neolignans and one new lignan (1–3) were obtained from the roots of Paeonia lactiflora. Their structures were unambiguously elucidated based on extensive spectroscopic analysis, single-crystal X-ray crystallography, and the calculated and experimental electronic circular dichroism (ECD) spectra. Compound 1 was a racemic mixture and successfully resolved into the anticipated enantiomers via ...
DOI:
10.1016/S1875-5364(22)60164-X

11. Bis-iridoids and other constituents from Scabiosa semipapposa

Author:
Samia Bendamene; Naima Boutaghane; Charlotte Sayagh; Abdulmagid Alabdul Magid; Zahia Kabouche; Chawki Bensouici; Laurence Voutquenne-Nazabadioko
Source:
Phytochemistry letters 2022 v.49 pp. 202-210
ISSN:
1874-3900
Subject:
Scabiosa; antioxidant activity; antioxidants; chemotaxonomy; flavonoids; glycosides; iridoids; lignans; mass spectrometry; phenol; spectral analysis
Abstract:
... Six undescribed bis-iridoids named Semipapposiridoids A–F (1–6) together with seventeen known compounds were obtained from the roots and aerial parts of Scabiosa semipapposa Salzm. ex DC. Among the known compounds, three lignans were isolated for the first time in Scabiosa species, whereas the other known constituents including iridoids, phenol glycosides and flavonoids were previously isolated fr ...
DOI:
10.1016/j.phytol.2022.04.005

12. Breeding history for shattering trait in sesame: classic to genomic approach

Author:
Moin Qureshi; D. Ray Langham; Stuart J. Lucas; Bulent Uzun; Engin Yol
Source:
Molecular biology reports 2022 v.49 no.7 pp. 7185-7194
ISSN:
0301-4851
Subject:
CRISPR-Cas systems; RNA interference; antioxidants; genes; genomics; lignans; mechanical harvesting; mechanization; molecular biology; mutagenesis; nucleases; oils; oilseed crops; protein content; zinc finger motif
Abstract:
... Sesame is an important oilseed crop that has high oil and protein content and unique antioxidant lignans. Capsule shattering at harvest is one of the most important problems affecting sesame production, with seed losses of up to 50%, making the crop unsuitable for mechanized harvesting. This paper provides an overview of breeding approaches addressing the capsule shattering trait in sesame and giv ...
DOI:
10.1007/s11033-022-07636-2

13. Caucasian Dragonheads: Phenolic Compounds, Polysaccharides, and Bioactivity of Dracocephalum austriacum and Dracocephalum botryoides

Author:
Nina I. Kashchenko; Gunay S. Jafarova; Javanshir I. Isaev; Daniil N. Olennikov; Nadezhda K. Chirikova
Source:
Plants 2022 v.11 no.16 pp. -
ISSN:
2223-7747
Subject:
Dracocephalum; antioxidant activity; arabinogalactan proteins; benzoic acid; chemical composition; cuisine; flavonoids; lignans; liquid chromatography; mass spectrometry; metabolites; methanol; phenylpropanoids; polysaccharides; traditional medicine; water solubility; Caucasus region
Abstract:
... Dracocephalum botryoides Steven and Dracocephalum austriacum L. are unexplored species of the Dracocephalum genus (Lamiaceae family) with a distribution in the Caucasus, where they are used in folk medicine and local cuisine. There are no data on the chemical composition of these Dracocephalum species. In this study, the application of a liquid chromatography-mass spectrometry technique for the me ...
DOI:
10.3390/plants11162126

14. Characterization of chemical constituents in Shuanghuanglian oral dosage forms by ultra‐high performance liquid chromatography coupled with time‐of‐flight mass spectrometry

Author:
Ruiyun Li; Yanru Zhu; Mingyan Ma; Min Lei; Yingchun Zhao; Ting Liu; Miao Yu; Yunli Zhao; Zhiguo Yu
Source:
Journal of separation science 2022 v.45 no.5 pp. 1020-1030
ISSN:
1615-9306
Subject:
Oriental traditional medicine; anthraquinones; caffeic acid; coumarins; flavonoids; iridoids; lignans; mass spectrometry; oral administration; separation; triterpenoids; ultra-performance liquid chromatography
Abstract:
... Shuanghuanglian is a common traditional Chinese medicine prescription. It is an herbal formula composed of Lonicerae Japonicae Flos, Scutellariae Radix, and Forsythiae Fructus. A comprehensive understanding of Shuanghuanglian oral dosage forms components was obtained using a method based on ultra‐high performance liquid chromatography coupled with time‐of‐flight mass spectrometry for the separatio ...
DOI:
10.1002/jssc.202100860

15. Characterization of chemical constituents with their antioxidant and anti-melanogenesis activities from the roots of Ampelopsis japonica

Author:
Chia-Lin Lee; Yun-Lian Jhan; Hsiu-Mei Chiang; Yi-Hung Chen; Chao-Jung Chen; Yuan-Shiun Chang
Source:
Natural product research 2022 v.36 no.12 pp. 3133-3137
ISSN:
1478-6427
Subject:
Ampelopsis; anthraquinones; cosmetics; free radicals; glycosylation; keratinocytes; lignans; melanin; melanoma; research; stilbenes
Abstract:
... Three glycosylated stilbenes (1–3), two anthraquinones (4, 5), one lignan (6), five tannins (7–11), two amino acids (12, 13), and one auronol (14) were isolated from the root of Ampelopsis japonica. All compounds, except for 4, 6, and 11 were obtained from this species for the first time. Compounds 6–9 could notably inhibit ROS generations in HaCaT keratinocyte cells with IC₅₀ values of 5.28, 4.83 ...
DOI:
10.1080/14786419.2021.1939335

16. Characterization, expression, and functional analysis of the pathogenesis-related gene PtDIR11 in transgenic poplar

Author:
Lingling Li; Weibo Sun; Pu Wang; Hongyan Li; Shamsur Rehman; Dawei Li; Qiang Zhuge
Source:
International journal of biological macromolecules 2022 v.210 pp. 182-195
ISSN:
0141-8130
Subject:
Populus trichocarpa; biosynthesis; cell membranes; coniferyl alcohol; disease resistance; ethylene; flavonoids; genes; immunity; jasmonic acid; lignans; lignin; lignin content; methanol; pathogenesis-related proteins; quantitative polymerase chain reaction; reverse transcription; salicylic acid; signal transduction
Abstract:
... Lignins and lignans are important for plant resistance to pathogens. Dirigent (DIR) proteins control the regio- and stereo-selectivity of coniferyl alcohol in lignan and lignin biosynthesis. DIR genes have been implicated in defense-related responses in several plant species, but their role in poplar immunity is unclear. We cloned PtDIR11 from Populus trichocarpa; we found that overexpression of P ...
DOI:
10.1016/j.ijbiomac.2022.05.012

17. Chemical and biological studies of Daphniphyllum oldhamii from Hunan Province, China

Author:
Yi Chen; Shou-Mao Shen; Min Yang; Ming-Zhi Su; Xiao-Ming Wang; Yue-Wei Guo
Source:
Phytochemistry 2022 v.199 pp. 113170
ISSN:
0031-9422
Subject:
Daphniphyllum; X-ray diffraction; lignans; plant biochemistry; spectral analysis; triterpenoids; China
Abstract:
... The fruits, twigs and leaves of Daphniphyllum oldhamii (Hemsl.) K. Rosenthal, collected from Longshan County, Hunan Province, China, were chemically investigated. Three undescribed daphniphyllum alkaloids, namely longshanoldhamines A‒C, and six known related ones have been isolated from the fruits, whereas two undescribed triterpenoids and one undescribed lignan, along with six known triterpenoids ...
DOI:
10.1016/j.phytochem.2022.113170

18. Chemical constituents and their antioxidant and anti-inflammatory activities from edible Cornus officinalis fruits

Author:
Zhongcan Peng; Yuming Wang; Jun He; Jia Zhang; Xuege Pan; Xiansheng Ye; Weiku Zhang; Jiekun Xu
Source:
European food research & technology 2022 v.248 no.4 pp. 1003-1010
ISSN:
1438-2377
Subject:
2,2-diphenyl-1-picrylhydrazyl; Cornus officinalis; acid hydrolysis; cell lines; electrospray ionization mass spectrometry; food production; food research; functional foods; inflammation; interleukin-6; lignans; lipopolysaccharides; macrophages; nitric oxide; phytochemicals; technology; traditional medicine
Abstract:
... Cornus officinalis fruits, an edible functional food with the tonic effect, belongs to the Cornaceae family. It is widely used in both traditional medicine and in some food production. A phytochemical study on the fruits of Cornus officinalis resulted in 20 structurally diverse compounds including 2 new lignans, named officinalignans A-B (1–2), and 2 new iridoids, named loganin-(4′-O-7″)-α-morroni ...
DOI:
10.1007/s00217-021-03940-6

19. Chemical constituents from Dracocephalum moldavica L. and their chemotaxonomic significance

Author:
Jiaming Wang; Jinfeng Sun; Mengjie Wang; Huiqiong Cui; Wei Zhou; Gao Li
Source:
Biochemical systematics and ecology 2022 v.102 pp. 104422
ISSN:
0305-1978
Subject:
Dracocephalum moldavica; chemotaxonomy; ecology; glycosides; lignans; monoterpenoids; norisoprenoids; phytochemicals; spectral analysis; triterpenoids
Abstract:
... A phytochemical investigation of the aerial parts of Dracocephalum moldavica L. (Lamiaceae) led to the isolation and characterization of 30 compounds, including eight lignans (1–8), seven phenols (9–15), five triterpenoids (16–20), four monoterpenoids (21–24), four glycosides (25–28) and two megastigmanes (29 and 30). The structures of these compounds were determined by spectroscopic data analysis ...
DOI:
10.1016/j.bse.2022.104422

20. Chemical constituents from Maytenus hookeri

Author:
Nian Jiang; Changyan Yu; Jing Hui; Jianxun Xie; Yuanyuan Wang; Jun Yang; Sanhua Li; Lingjie Meng
Source:
Biochemical systematics and ecology 2022 v.104 pp. 104475
ISSN:
0305-1978
Subject:
Maytenus; chemotaxonomy; ecology; lignans; phenylpropanoids; phytochemicals; saponins; spectral analysis; triterpenoids
Abstract:
... A phytochemical investigation on the branches of Maytenus hookeri resulted in the isolation and identification of fourteen compounds, including one new triterpene saponin (1), five phenylpropanoids (2–6), and eight lignans (7–14). The chemical structures of these compounds were determined by comprehensive spectroscopic data analysis, such as UV, IR, 1D/2D NMR, mass spectra, and data from the liter ...
DOI:
10.1016/j.bse.2022.104475

21. Chemical constituents from Salvinia natans (L.) All. (Salviniaceae) and their chemotaxonomic significance

Author:
Hien Giang Pham; Manh Tuan Ha; Thao Quyen Cao; Ngoc Khanh Vu; Thi Thanh Le; Byung Sun Min
Source:
Biochemical systematics and ecology 2022 v.102 pp. 104410
ISSN:
0305-1978
Subject:
Salvinia natans; chemotaxonomy; ecology; lignans; norisoprenoids; phenanthrenes; phytochemicals; spectral analysis
Abstract:
... The phytochemical research on Salvinia natans (L.) All. resulted in the isolation of 11 compounds, subdivided into four steroids (1–4), three megastigmanes (5–7), two lignans (8 and 9), one phenanthrene (10), and one nepetolactone derivative (11). The structures of these compounds were elucidated mainly by NMR spectroscopic analysis and comparison with the published data. All these compounds were ...
DOI:
10.1016/j.bse.2022.104410

22. Chemical constituents from the aerial parts of Achillea alpina and their chemotaxonomic significance

Author:
Xiuwei Li; Xia Wu; Qiang Guo; Changli Liu; Hucheng Yue; Jiayi Tian; Zongyang Liu; Meng Xiao; Ang Li; Zhongqi Ning; Ke Zan; Xiaoqing Chen
Source:
Biochemical systematics and ecology 2022 v.101 pp. 104381
ISSN:
0305-1978
Subject:
Achillea; chemotaxonomy; ecology; lignans; phytochemicals; sesquiterpenoids; spectral analysis
Abstract:
... Phytochemical investigation of the aerial parts of Achillea alpina led to the isolation of sixteen compounds, including six sesquiterpenes (1-6), two polyacetylenic alcohols (7-8), three lignans (9-11), and five fatty acids (12-16). Their structures were identified by spectroscopic analysis of UV, IR, MS and NMR, and in comparison with the those reported data in the references. Among them, five co ...
DOI:
10.1016/j.bse.2022.104381

23. Chemical constituents from the fruits of Illicium simonsii and their antiviral activity and neuroprotective effect

Author:
Guo-Zhu Su; Mi Li; Xiao-Jing Wang; Ru-Bing Wang; Shuang-Gang Ma; Dan Zhang; Xiao-Liang Wang; Li Li; Yun-Bao Liu; Jing Qu; Yu-Huan Li; Yong Li; Shi-Shan Yu
Source:
Phytochemistry 2022 v.202 pp. 113323
ISSN:
0031-9422
Subject:
Illicium; X-ray diffraction; antiviral properties; diterpenoids; lignans; neuroprotective effect; plant biochemistry; sesquiterpenoids; spectral analysis; viruses
Abstract:
... One undescribed diterpenoid illisimonone A, four undescribed sesquiterpenes named (±)-simonones A, simonterpenoids A and B, and two undescribed lignans, illisimonins A and B, along with five known compounds were isolated from the fruits of Illicium simonsii. Their structures were elucidated by extensive spectroscopic data. The absolute configuration of illisimonone A was determined by single-cryst ...
DOI:
10.1016/j.phytochem.2022.113323

24. Chemical constituents from the leaves of Caesalpinia bonduc (L.) Roxb. and their chemotaxonomic significance

Author:
Le Thi Huyen; Vu Hoang Son; Truong Thi Viet Hoa; Luong Thi My Hanh; Seo Yohan; Park SeonJu; Nguyen Xuan Nhiem; Dan Thi Thuy Hang; Phan Van Kiem; Bui Huu Tai
Source:
Biochemical systematics and ecology 2022 v.100 pp. 104376
ISSN:
0305-1978
Subject:
Caesalpinia bonduc; chemotaxonomy; ecology; flavonoids; lignans; spectral analysis
Abstract:
... Caesalpinia bonduc (L.) Roxb. is an important herb in Ayurvedic medicines. In this study, five lignans (1–5), two phloroglucinols (6–7), five flavonoids (8–12) and four phenolics (13–16) were identified from the leaves of C. bonduc by comparison with spectroscopic data published in the literature. To the best of our knowledge, all of these identified phytochemicals were reported for the first time ...
DOI:
10.1016/j.bse.2021.104376

25. Chemical constituents from the roots of Actinidia valvata Dunn

Author:
Changwei Song; Chunbo Yu; Ying Qin; Jing Hui; Yong Zhang; Shengyan Qian; Lin Xu; Yun Liu
Source:
Biochemical systematics and ecology 2022 v.100 pp. 104371
ISSN:
0305-1978
Subject:
Actinidia; butanol; chemotaxonomy; coumarins; ecology; glycosides; lignans; phenylpropanoids; secondary metabolites; spectral analysis
Abstract:
... A previous undescribed dihydrobenzofuran neolignan (1), as well as eleven known phenolic derivatives (2–12) were isolated from the n-butanol fraction of the roots of Actinidia valvata Dunn, including five phenylpropanoids (2–6), four phenolic glycosides (7–10) and two coumarins (11–12). The chemical structures of these compounds were identified by means of extensive spectroscopic analysis and comp ...
DOI:
10.1016/j.bse.2021.104371

26. Chemical constituents of Antidesma bunius aerial parts and the anti-AGEs activity of selected compounds

Author:
Hieu Nguyen-Ngoc; Mostafa Alilou; Séverine Derbré; Patricia Blanchard; Giang Nam Pham; Duc Trong Nghiem; Pascal Richomme; Hermann Stuppner; Markus Ganzera
Source:
Phytochemistry 2022 v.202 pp. 113300
ISSN:
0031-9422
Subject:
Antidesma bunius; Euphorbiaceae; advanced glycation end products; diabetes; lignans; metabolites; moieties; rheumatoid arthritis; rutin; traditional medicine
Abstract:
... Thirty-three natural products were isolated from the aerial parts of Antidesma bunius, Euphorbiaceae, a plant used in Vietnamese traditional medicine against rheumatoid arthritis. All compounds were reported the first time for this species, and nine constituents resembled undescribed natural products, noticeably three coumarinolignans with 2,2-dimethyl-1,3-dioxolane moiety, two cyclopeptides, and ...
DOI:
10.1016/j.phytochem.2022.113300

27. Cistanche deserticola polysaccharides extracted from Cistanche deserticola Y.C. Ma promote the differentiation of mouse female germline stem cells in vitro

Author:
Yikai Qiu; Yanping Zhang; Hehe Ren; Yingxin Zhang; Xinrui Liu; Jing Pu; Jianqiang Yu; Xiaoli Yu; Xiuying Pei
Source:
Journal of ethnopharmacology 2022 v.296 pp. 115495
ISSN:
0378-8741
Subject:
Cistanche deserticola; Oriental traditional medicine; Western blotting; bone morphogenetic proteins; cell differentiation; cell proliferation; cell structures; cell viability; culture media; females; fluorescent antibody technique; gene expression; gene expression regulation; genes; glycosides; iridoids; lignans; mice; oocytes; phenylethyl alcohol; polysaccharides; quantitative polymerase chain reaction; retinoic acid; sequence analysis; signal transduction; synaptonemal complex; China
Abstract:
... Traditional Chinese herbal medicine Cistanche deserticola Y.C. Ma has been recorded and treatment for infertility and impotence since ancient times, which is widely distributed in northwest China, and is mainly composed of phenylethanol glycosides, iridoids, lignans, polysaccharides, alkaloids, etc. C. deserticola polysaccharides (CDPs) is one of its main active ingredients, studies of its effect ...
DOI:
10.1016/j.jep.2022.115495

28. Combination of UHPLC‐Q Exactive‐Orbitrap MS and network pharmacology to reveal the mechanism of Eucommia ulmoides leaves in the treatment of osteoarthritis

Author:
Tao Liu; Xingze Cao; Dongmin Cao
Source:
Journal of food biochemistry 2022 v.46 no.8 pp. e14204
ISSN:
0145-8884
Subject:
Eucommia ulmoides; flavonoids; iridoids; lignans; medicine; osteoarthritis; pharmacology; quality of life; rapid methods; therapeutics; ultra-performance liquid chromatography
Abstract:
... Osteoarthritis (OA) is a disabling disease and seriously affects the quality of life of patients. is A potential medicine for the treatment of OA is Eucommia ulmoides leaves (EULs). However, its active compounds and therapeutic mechanisms are unclear. Therefore, it is necessary to develop a method using LC–MS and network pharmacology for the detection and identification of compounds and the mechan ...
DOI:
10.1111/jfbc.14204

29. Combined transcriptome and metabolome analysis of Nerium indicum L. elaborates the key pathways that are activated in response to witches’ broom disease

Author:
Shengjie Wang; Shengkun Wang; Ming Li; Yuhang Su; Zhan Sun; Haibin Ma
Source:
BMC plant biology 2022 v.22 no.1 pp. 291
ISSN:
1471-2229
Subject:
Nerium oleander; Sophora chrysophylla; biosynthesis; brooms; coumarins; disease incidence; flavonoids; gene expression regulation; host-pathogen relationships; hypersensitive response; lignans; linoleic acid; metabolites; metabolome; metabolomics; nicotinamide; ornamental plants; pathogens; phenylpropanoids; phloem; plant hormones; signal transduction; surveys; transcriptome; tricarboxylic acid cycle; unigenes; China
Abstract:
... BACKGROUND: Nerium indicum Mill. is an ornamental plant that is found in parks, riversides, lakesides, and scenic areas in China and other parts of the world. Our recent survey indicated the prevalence of witches’ broom disease (WBD) in Guangdong, China. To find out the possible defense strategies against WBD, we performed a MiSeq based ITS sequencing to identify the possible casual organism, then ...
DOI:
10.1186/s12870-022-03672-z

30. Comparative effects of sesame lignans (sesamin, sesamolin, and sesamol) on oxidative stress and lipid metabolism in steatosis HepG2 cells

Author:
Longkai Shi; Emad Karrar; Ruijie Liu; Ming Chang; Xingguo Wang
Source:
Journal of food biochemistry 2022 v.46 no.8 pp. e14180
ISSN:
0145-8884
Subject:
beta oxidation; catabolism; cholesterol; fatty liver; genes; lignans; lipemic effect; lipogenesis; liver; models; oxidative stress; peroxisome proliferator-activated receptors; sesame oil; therapeutics
Abstract:
... Non‐alcoholic fatty liver disease (NAFLD) can be attributed to the imbalance between lipogenesis and lipidolysis in the liver. Sesame lignans (sesamin, sesamolin, and sesamol) are unique bioactive compounds responsible for the nutritional function of sesame oils. However, the preventive effects of three lignans on oxidative stress and lipid metabolism in steatosis HepG2 cells have not been compare ...
DOI:
10.1111/jfbc.14180

31. Comparative metabolite fingerprinting of chia, flax and sesame seeds using LC-MS untargeted metabolomics

Author:
Federico I. Brigante; Natalia S. Podio; Daniel A. Wunderlin; Maria V. Baroni
Source:
Food chemistry 2022 v.371 pp. 131355
ISSN:
0308-8146
Subject:
Salvia hispanica; data collection; flax; food chemistry; lignans; metabolites; metabolomics; nutritive value; polyphenols; seeds
Abstract:
... Chia, flax, and sesame seeds are well known for their nutritional quality and are commonly included in bakery products. So far, the development of methods to verify their presence and authenticity in foods is a requisite and a raised need. In this work we applied untargeted metabolomics to propose authenticity markers. Seeds were analyzed by HPLC-MS/MS and 9938 features in negative mode and 9044 i ...
DOI:
10.1016/j.foodchem.2021.131355

32. Comparative metabolomic study of three clones of Eucommia ulmoides wood

Author:
Shuan Ren; Manrong Zha; Youji Li; Ke Song; Jian He; Shima Liu; Jie Guo; Kegang Li; Xianwu Zhou
Source:
Journal of wood chemistry and technology 2022 v.42 no.4 pp. 318-329
ISSN:
1532-2319
Subject:
Eucommia ulmoides; biosynthesis; coumarins; flavonoids; lignans; lysine; metabolomics; nucleotides; secondary metabolites; terpenoids; wood; wood chemistry
Abstract:
... It is important to reveal the differences in the metabolites of different clones of Eucommia wood to explore the beneficial components of Eucommia wood and the selection of Eucommia wood. In this study, an extensive targeted metabolomic analysis was conducted on three different clones of Eucommia wood, Huazhong 12 Eucommia (HZ), Cili Eucommia (CL), and Miye Eucommia (MY), using UPLC-EI-MS/MS analy ...
DOI:
10.1080/02773813.2022.2088794

33. Comprehensive characterization and identification of chemical constituents in Yangwei decoction using ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time‐of‐flight tandem mass spectrometry

Author:
Shuaishuai Fan; Baolin Li; Yurou Tian; Wei Feng; Liying Niu
Source:
Journal of separation science 2022 v.45 no.5 pp. 1006-1019
ISSN:
1615-9306
Subject:
Oriental traditional medicine; cold; electrospray ionization mass spectrometry; flavonoids; glycosides; lactones; lignans; pharmacology; separation; tandem mass spectrometry; triterpenoids; ultra-performance liquid chromatography
Abstract:
... Yangwei decoction, a classical traditional Chinese medicine prescription, has been widely used to treat exogenous cold and internal injury with damp stagnation for many centuries. However, its systematic chemical profiling remains ambiguous, which has hampered the interpretation of pharmacology and the mechanism of its formula. In the present study, ultra‐performance liquid chromatography coupled ...
DOI:
10.1002/jssc.202100723

34. Consumption of sesame seeds and sesame products has favorable effects on blood glucose levels but not on insulin resistance: A systematic review and meta‐analysis of controlled clinical trials

Author:
Mohammad Hassan Sohouli; Niloufar Haghshenas; Ángela Hernández‐Ruiz; Farzad Shidfar
Source:
Phytotherapy research 2022 v.36 no.3 pp. 1126-1134
ISSN:
0951-418X
Subject:
blood glucose; blood serum; glucose; humans; insulin; insulin resistance; lignans; meta-analysis; metabolism; phytotherapy; research; sesame oil; systematic review
Abstract:
... Sesame, with an oily seed containing oil, lignans, and proteins, is a popular plant that has demonstrated health benefits such as antioxidative, antiobesity, and antiinflammatory effects. In this systematic review and meta‐analysis, we aimed to summarize the effect of sesame seeds and their consumption compared to a control group on blood glucose and insulin resistance in human adults. PubMed/MEDL ...
DOI:
10.1002/ptr.7379

35. Copper nanoclusters-based fluorescent sensor array to identify metal ions and dissolved organic matter

Author:
Jinming Xu; Huangmei Zhou; Yixue Zhang; Yu Zhao; Hao Yuan; Xiaoxiao He; Ying Wu; Sanjun Zhang
Source:
Journal of hazardous materials 2022 v.428 pp. 128158
ISSN:
0304-3894
Subject:
discriminant analysis; fluorescence; glutathione; histidine; lignans; polyethyleneimine; principal component analysis; rapid methods; riparian areas; seawater; tap water; water pollution; water quality
Abstract:
... In recent years, the prevention and control of water pollution has received extensive attention. There is a need to develop simple and effective strategies for the rapid detection of metal ions and dissolved organic matter (DOM) in order to improve water quality. To this end, the first copper nanoclusters (CuNCs)-based fluorescent sensor array was done to identify 12 metal ions (Pb²⁺, Fe³⁺, Cu²⁺, ...
DOI:
10.1016/j.jhazmat.2021.128158

36. Correlation between phytocompounds and pharmacological activities of Boerhavia diffusa Linn with traditional-ethnopharmacological insights

Author:
Praveen Kumar Gaur; Sameer Rastogi; Kanak Lata
Source:
Phytomedicine plus 2022 v.2 no.2 pp. 100260
ISSN:
2667-0313
Subject:
Ayurvedic medicine; Boerhavia diffusa; antioxidants; cardiovascular diseases; ecdysteroids; edema; humans; inflammation; kidneys; lignans; nephroprotective effect; nutrient content; polyphenols; rotenoids; wastelands; wet season; Africa; Asia; North America; South America
Abstract:
... : The human body is almost 70% water and fluid imbalance has been a classic symptom of severe underlying conditions, i.e., hepatic disorders, kidney disorders, cardiovascular disease and inflammation. Boerhavia diffusa Linn. is a pantropical herb used in traditional medicine systems worldwide for inflammation, liver-kidney disorders, skin problems, etc. Ethnopharmacological reports of B. diffusa c ...
DOI:
10.1016/j.phyplu.2022.100260

37. Corrigendum to “A new phenylethyl glycoside and a new dibenzocyclooctadiene lignan from the leaves of Kadsura coccinea (Lem.) A. C. Smith” [Phytochem. Lett. 45 (2021) 57–62]

Author:
Le Huyen Tram; Tran Thu Huong; Le Thi Thuy; Nguyen Van Thong; Nguyen Tuan Anh; Nguyen Hoang Minh; Tran Thi Minh; Nguyen Thi Hong Phuong; Tran Thu Ha; Nguyen Hai Dang; Duc Dat Le; Pham Phuoc Dien; Mina Lee
Source:
Phytochemistry letters 2022 v.48 pp. 132-137
ISSN:
1874-3900
Subject:
Kadsura coccinea; circular dichroism spectroscopy; glycosides; hydrolysis; lignans; lipopolysaccharides; mass spectrometry; nitric oxide; nuclear magnetic resonance spectroscopy; plant biochemistry
Abstract:
... A new phenylethyl glycoside (1), (S)-1-phenylethyl-6-α-L-arabinopyranosyl-β-D-glucopyranoside), and a new dibenzocyclooctadiene lignan (7), Kasuracin A, together with seven known compounds, were isolated and identified from the leaves of Kadsura coccinea. Their structures were determined by analysis of multinuclear and multidimensional nuclear magnetic resonance (NMR), circular dichroism (CD), mas ...
DOI:
10.1016/j.phytol.2021.09.013

38. Coumarins and lignans from the roots of Zanthoxylum nitidum

Author:
Jian-Hui Su; Ming-Qiang Wang; Li-Ping Zhu; Wei-Qun Yang; Shi-Qin Jiang; Zhong-Xiang Zhao; Zhang-Hua Sun
Source:
Biochemical systematics and ecology 2022 v.101 pp. 104399
ISSN:
0305-1978
Subject:
Oriental traditional medicine; Zanthoxylum nitidum; chemotaxonomy; coumarin; ecology; glycosides; lignans; phytochemicals
Abstract:
... The phytochemical investigation of the Chinese medicine Zanthoxylum nitidum led to the isolation of a new coumarin glycoside (1), seven known coumarins (2–8) and two known lignan glycosides (9–10). Their structures were elucidated based on extensive spectroscopic methods (HRESIMS, 1D and 2D NMR experiments) and by comparison with literature data. The new compound (1) was a linear furanocoumarin gl ...
DOI:
10.1016/j.bse.2022.104399

39. Cytotoxic alkaloids from the root of Zanthoxylum paracanthum (mildbr) Kokwaro

Author:
Leonidah Kerubo Omosa; Vaderament-A Nchiozem-Ngnitedem; Justus Mukavi; Brenda Atieno Okoko; Helder Ombui Nyaboke; Ibrahim Hashim; Jackson Obegi Matundura; Thomas Efferth; Michael Spiteller
Source:
Natural product research 2022 v.36 no.10 pp. 2518-2525
ISSN:
1478-6427
Subject:
Zanthoxylum; amides; cell lines; cytotoxicity; doxorubicin; lignans; multiple drug resistance; neoplasm cells; research; spectroscopy
Abstract:
... Chemical investigation of the root of Zanthoxylum paracanthum afforded 1 new alkamide derivative, (2E,4E)-6-oxo-N-isobutyldeca-2,4-dienamide (1) together with 10 known congeners including one phenolic amide (2), four benzophenanthridines (3 − 6), three indolonaphthyridines (7 − 9) and two lignans (10 and 11). Their structures were elucidated by a combination of spectroscopic and spectrometric data ...
DOI:
10.1080/14786419.2021.1913586

40. Depletion of cyanogenic glycosides in whole flaxseed via Lactobacillaceae fermentation

Author:
Chao Huang; Timothy J. Tse; Sarah K. Purdy; Farley Chicilo; Jianheng Shen; Venkatesh Meda; Martin J. T. Reaney
Source:
Food chemistry 2022 pp. 134441
ISSN:
0308-8146
Subject:
Lactobacillaceae; cyanogenic glycosides; fatty acid composition; feeds; fermentation; food chemistry; functional foods; imports; ingestion; lignans; linseed; linseed oil; mixed culture; nutrient uptake
Abstract:
... Flaxseed is categorized as a functional food due to its abundance in oil, α-linolenic acid, dietary fibres, and lignans. However, flaxseed contains cyanogenic glycosides (CGs). Ingestion of CGs can influence nutrient absorption and induce adverse health effects. Due to the presence of CGs in flaxseed many countries prohibit the import and sale of flaxseed and flaxseed-based foods. In this study, w ...
DOI:
10.1016/j.foodchem.2022.134441

41. Dirigent gene family is involved in the molecular interaction between Panax notoginseng and root rot pathogen Fusarium solani

Author:
Jie Deng; Ruipan Guan; Tingting Liang; Linlin Su; Feng Ge; Xiuming Cui; Diqiu Liu
Source:
Industrial crops and products 2022 v.178 pp. 114544
ISSN:
0926-6690
Subject:
Fusarium solani; Nicotiana tabacum; Panax notoginseng; Sclerotinia sclerotiorum; biosynthesis; cell walls; genes; lignans; lignin; pathogens; phylogeny; quantitative polymerase chain reaction; root rot; tobacco
Abstract:
... Root rot, mainly caused by Fusarium solani, severely reduces the yield and quality of Panax notoginseng (Burk) F.H. Chen. Dirigent (DIR) proteins catalyze the coupling of lignin monomers during lignin biosynthesis, making them important components of plant defense systems. In this study, a small P. notoginseng DIR gene family was isolated from P. notoginseng. A phylogenetic analysis indicated that ...
DOI:
10.1016/j.indcrop.2022.114544

42. Distribution of lignans in Panicum miliaceum, Fagopyrum esculentum, Fagopyrum tataricum, and Amaranthus hypochondriacus

Author:
Jana Pexová Kalinová; Iveta Marešová; Jan Tříska; Naděžda Vrchotová
Source:
Journal of food composition and analysis 2022 v.106 pp. 104283
ISSN:
0889-1575
Subject:
Amaranthus hypochondriacus; Fagopyrum esculentum; Fagopyrum tataricum; Panicum miliaceum subsp. miliaceum; buckwheat; food composition; lignans; lignin content; roots
Abstract:
... The distribution of lignans within common millet, common buckwheat, tartary buckwheat, and amaranth plants, as well as any differences of their contents within their different varieties and samples from different growing seasons, were determined by LC–MS analyses. Roots were the plant part highest in the total amount of lignans in common buckwheat, tartary buckwheat, and common millet; which is in ...
DOI:
10.1016/j.jfca.2021.104283

43. Distribution, biosynthesis and therapeutic potential of lignans

Author:
Navdeep Singh Plaha; Sumegha Awasthi; Ayushi Sharma; Nutan Kaushik
Source:
3 Biotech 2022 v.12 no.10 pp. 255
ISSN:
2190-572X
Subject:
anticarcinogenic agents; antioxidants; biosynthesis; gene expression regulation; intestinal microorganisms; lignans; linseed; mammals; therapeutics; toxicity
Abstract:
... Lignans have long been known for their abundant therapeutic properties due to their polyphenolic structure. Linseed is the richest plant source of lignans and has been studied widely for their properties. The most prevalent lignan, secoisolariciresinol diglucoside (SDG), is consumed with linseed and converted into mammalian lignans, enterodiol (END) and enterolactone (ENL), by the gut microbiota. ...
DOI:
10.1007/s13205-022-03318-9

44. Dolominol a and B, two new neolignans from Dolomiaea souliei (Franch.) C.Shih

Author:
Man Yi; Fan-Cheng Meng; Shen-Yue Qu; Jing-Xin Mao; Guowei Wang; Mingxing Liu; Zhi-Hua Liao; Min Chen
Source:
Natural product research 2022 v.36 no.15 pp. 3909-3916
ISSN:
1478-6427
Subject:
alcohols; hepatoprotective effect; lignans; research
Abstract:
... Two new neolignans, dolominol A (1) and dolominol B (2), together with 12 known lignans, erythro-(7S,8R)-guaiacyl-glycerol-β-O-4′-dihydroconiferyl ether (3), threo-(7R,​8R)-1-​(4-​hydroxy-​3-​methoxyphenyl)​-​2-{4-[(E)-​3-​hydroxy-​1-​propen​yl)​]-​2-​methoxyphenoxy}-1,​3-​propanediol (4), (-)-dihydrodehydrodiconiferyl alcohol (5), (-)-massoniresinol (6), vladinol D (7), syringaresinol (8), prinse ...
DOI:
10.1080/14786419.2021.1897125

45. Effect of microwave exposure to flaxseed on the composition, structure and techno-functionality of gum polysaccharides

Author:
Xiao Yu; Shasha Huang; Fan Yang; Xiaopeng Qin; Chengzhen Nie; Qianchun Deng; Fenghong Huang; Qisen Xiang; Yingying Zhu; Fang Geng
Source:
Food hydrocolloids 2022 v.125 pp. 107447
ISSN:
0268-005X
Subject:
antioxidants; crosslinking; depolymerization; emulsions; enthalpy; gels; hydrocolloids; lignans; linseed; molecular weight; polysaccharides; seed coat; thermogravimetry; viscoelasticity
Abstract:
... The current study aimed to explore the potential influences of microwave exposure to flaxseed (150 g samples, 700 W for 1–5 min) on the several techno-functional properties of flaxseed gum (FG), focusing on the changes in composition, surface morphology and multiscale structure. The results showed that microwave exposure to flaxseed actually resulted in evident etching effect on seed coat and favo ...
DOI:
10.1016/j.foodhyd.2021.107447

46. Effect of ultrasonic pretreatment for lignan accumulation in flax sprouts (Linum usitatissimum L.)

Author:
Yixin Wu; Hong Wang; Fangyang Gao; Yufu Wang; Xinbo Guo; Caisheng Qiu
Source:
Food chemistry 2022 v.370 pp. 131067
ISSN:
0308-8146
Subject:
Linum usitatissimum; biosynthesis; caffeic acid; ferulic acid; flax; food chemistry; lignans; p-coumaric acid; ultrasonics; vegetables
Abstract:
... This study evaluated different ultrasonic treatments for lignan biosynthesis in two varieties of flax sprouts. Results showed that lignans in flax sprouts significantly raised with ultrasonic pretreatment. Secoisolariciresinol diglucoside dramatically increased by about 6-fold at the flax sprouts. Ultrasonic pretreatment could also affect the accumulation of caffeic acid and p-coumaric acid in fla ...
DOI:
10.1016/j.foodchem.2021.131067

47. Effects of dibenzylbutyrolactone lignans arctigenin and trachelogenin on the motility of isolated rat ileum

Author:
Peter Kiplang’at Koech; Imre Boldizsár; Arpád Dobolyi; Petra Varró
Source:
Toxicology reports 2022 v.9 pp. 1222-1232
ISSN:
2214-7500
Subject:
Arctium lappa; Cirsium arvense; adults; calcium; calcium channel blockers; calcium channels; dose response; gastrointestinal motility; ileum; lignans; males; mechanism of action; nitric oxide synthase; rats; toxicology
Abstract:
... Dibenzylbutyrolactone-type lignans are phenolic compounds of medical importance. The purpose of the study was to determine the effects of two such lignans, arctigenin and trachelogenin on the motility of isolated rat ileum and obtain indications on their mechanism of action. They were isolated from Arctium lappa and Cirsium arvense, respectively, which have been used traditionally to treat gastroi ...
DOI:
10.1016/j.toxrep.2022.05.019

48. Exploring the active compounds and potential mechanism of the anti-nonalcoholic fatty liver disease activity of the fraction from Schisandra chinensis fruit extract fraction based on multi-technology integrated network pharmacology

Author:
Bin Li; Qi Xiao; Jianuo Zhang; Yumeng Wang; Jiushi Liu; Bengang Zhang; Haitao Liu
Source:
Journal of ethnopharmacology 2022 pp. 115769
ISSN:
0378-8741
Subject:
Oriental traditional medicine; Schisandra chinensis; active ingredients; alanine transaminase; aspartate transaminase; blood serum; cholesterol; ethanol; fatty liver; fruit extracts; fruits; gene expression; glucose tolerance; glucose tolerance tests; high fat diet; human cell lines; insulin; insulin resistance; insulin tolerance test; lignans; liver; malondialdehyde; mass spectrometry; mice; models; petroleum; pharmacology; reverse transcriptase polymerase chain reaction; triacylglycerols
Abstract:
... Schisandra chinensis fruit is a well-known traditional Chinese medicine (TCM) that has been used to treat various liver diseases. Our previous study revealed that its extract is effective against nonalcoholic fatty liver disease (NAFLD). This study aimed to elucidate the active components and explore the underlying mechanisms of action of S. chinensis fruit in the treatment of NAFLD. A HepG2 cell ...
DOI:
10.1016/j.jep.2022.115769

49. Flavone, flavanone and flavonol metabolism from soybean and flaxseed extracts by the intestinal microbiota of adults and infants

Author:
José M Landete
Source:
Journal of the science of food and agriculture 2022 v.102 no.6 pp. 2575-2583
ISSN:
0022-5142
Subject:
adults; agriculture; antioxidant activity; apigenin; bioavailability; catabolism; catechol; flavanones; intestinal microorganisms; isoflavones; kaempferol; lignans; linseed; luteolin; myricetin; protocatechuic acid; quercetin; soybeans
Abstract:
... BACKGROUND: Flaxseed and soybean are an important source of lignans and flavonoids. Previously, the metabolism of isoflavones and lignans from soybean and flaxseed extracts by the microbiota of adult individuals (n = 14) and infants (n = 23) was analyzed. Thus, the present study aimed to examine the metabolism of flavones, flavanones and flavonols, as well as the production of phenolic acids, by t ...
DOI:
10.1002/jsfa.11599

50. Functional components of peanuts (Arachis Hypogaea L.) and health benefits: A review

Author:
S. Çiftçi; G. Suna
Source:
Future foods 2022 v.5 pp. 100140
ISSN:
2666-8335
Subject:
Arachis hypogaea; Mediterranean diet; diabetes; economic development; energy; human health; hypertension; isoflavonoids; lignans; models; oils; peanuts; people; phytosterols; stilbenes; South America; Virginia
Abstract:
... Peanut (Arachis hypogea L.) is one of the most consumed oil seeds worldwide. It belongs to the legume family and has spread to other parts of the world from South America. Peanut has been classified as Virginia, Runner, Spanish, and Valencia depending on the seed stagnation, branching pattern, the plant maturation period, and economic growth. People have consumed peanuts as raw, boiled, oil extrac ...
DOI:
10.1016/j.fufo.2022.100140