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- Author:
- Tomoki Iguchi; Minpei Kuroda; Nanami Akiyama; Mariko Hashimoto; Yoshihiro Mimaki
- Source:
- Natural product research 2022 v.36 no.4 pp. 1004-1008
- ISSN:
- 1478-6427
- Subject:
- Betula pubescens var. pubescens; aldehyde reductase; bark; flavanones; glucosides; lignans; methyl salicylate; monoterpenoids; research; spectral analysis; triterpenoids
- Abstract:
- ... Systematic phytochemical investigation of the bark and leaves of Betula alba was independently conducted. A new cyclic diarylheptanoid glucoside (1), five diarylheptanoids (2–6), a phenylethanoid (7), a methyl salicylate glycoside (8), a dihydrobenzofuran glucoside (9), an arylbutanoid glycoside (10), two lignan glycosides (11 and 12), a flavanone glucoside (13), and a triterpene (14) were isolate ...
- DOI:
- 10.1080/14786419.2020.1839455
- https://doi.org/10.1080/14786419.2020.1839455
- Author:
- Jun-Sheng ZHANG; De-Feng XU; Xin-Xin CAO; Yin-Yin WANG; Hua ZHANG
- Source:
- Chinese journal of natural medicines 2021 v.19 no.7 pp. 500-504
- ISSN:
- 1875-5364
- Subject:
- Tinospora sinensis; circular dichroism spectroscopy; density functional theory; glucosides; lignans; lipopolysaccharides; macrophages; mice; nitric oxide; spectral analysis
- Abstract:
- ... Two new lignan glucosides, tinsinlignans A and B (1 and 2), two new oxyneolignans, tinsinlignans C and D (3 and 4), along with one known analogue (5), were isolated from the stems of Tinospora sinensis. The structures of the new compounds were elucidated based on analysis of spectroscopic data, and the absolute configuration of 1 was determined through electronic circular dichroism (ECD) calculati ...
- DOI:
- 10.1016/S1875-5364(21)60049-3
- https://doi.org/10.1016/S1875-5364(21)60049-3
- Author:
- Yutong Qi; Se-In Choi; So-Ri Son; Hee-Soo Han; Hye Shin Ahn; Yu-Kyong Shin; Sun Hee Lee; Kyung-Tae Lee; Hak Cheol Kwon; Dae Sik Jang
- Source:
- Plants 2020 v.9 no.9 pp. -
- ISSN:
- 2223-7747
- Subject:
- Campanula takesimana; Oriental traditional medicine; anti-inflammatory activity; chemical composition; chromatography; ferulic acid; glucosides; herbal medicines; herbs; kaempferol; leaves; lignans; lipopolysaccharides; nuclear magnetic resonance spectroscopy; prostaglandins; quercetin; spectral analysis; Korean Peninsula
- Abstract:
- ... Campanula takesimana Nakai (Campanulaceae; Korean bellflower) is one of the endemic herbs of Korea. The plant has been used as traditional medicines for treating asthma, tonsillitis, and sore throat in Korea. A hot water extract of the leaves of C. takesimana exhibited a significant inhibitory effect on lipopolysaccharide (LPS)-stimulated prostaglandin E₂ (PGE₂) production. Repetitive chromatograp ...
- DOI:
- 10.3390/plants9091232
- https://doi.org/10.3390/plants9091232
- Author:
- Walid Khitri; Dalila Smati; Anne-Claire Mitaine-Offer; Thomas Paululat; Marie-Aleth Lacaille-Dubois
- Source:
- Biochemical systematics and ecology 2020 v.91 pp. 104054
- ISSN:
- 0305-1978
- Subject:
- Phlomis; carbon; chemical composition; chemotaxonomy; glucosides; iridoids; leaves; lignans; mass spectrometry; metabolites; norisoprenoids; nuclear magnetic resonance spectroscopy; phenylpropanoids; phytochemicals; roots; spectral analysis; stable isotopes
- Abstract:
- ... A phytochemical investigation of the leaves and roots of Phlomis bovei Noë (Lamiaceae) led to the isolation of sixteen compounds, including iridoids (1, 2, 3), megastigmanes (4, 5), phenylpropanoids (6, 7, 8, 9, 10), lignans (11, 12, 13, 14), a nortriterpene (15), and a phenyl glucoside (16). Compounds (1, 2, 4, 5, 6, 10) were obtained from the leaves and compounds (1, 2, 3, 7, 8, 9, 11, 12, 13, 1 ...
- DOI:
- 10.1016/j.bse.2020.104054
- https://doi.org/10.1016/j.bse.2020.104054
- Author:
- Joseph Sakah Kaunda; Ying-Jun Zhang
- Source:
- Biochemical systematics and ecology 2020 v.90 pp. 104031
- ISSN:
- 0305-1978
- Subject:
- Solanum incanum; chemical composition; chemotaxonomy; coumarin; fruits; glucosides; glycoalkaloids; lignans; monoterpenoids; nuclear magnetic resonance spectroscopy; phytochemicals; spectral analysis
- Abstract:
- ... Phytochemical investigation of the fruits of Solanum incanum L. resulted in the isolation of nine compounds, including three steroidal glycoalkaloids (1-3), two neolignans (4–5), two simple phenolics (6–7), one monoterpene glycoside (8), and one coumarin glucoside (9). The structure elucidation of isolated compounds was determined based on NMR and mass spectral data. Compounds 4 and 9 were isolate ...
- DOI:
- 10.1016/j.bse.2020.104031
- https://doi.org/10.1016/j.bse.2020.104031
- Author:
- Hyoung-Geun Kim; Hyun-Ji Oh; Jung-Hwan Ko; Sun-Woo Joo; Yeong-Geun Lee; Yun-Su Baek; Dae Young Lee; Nam-In Baek
- Source:
- Chemistry of natural compounds 2019 v.55 no.4 pp. 610-613
- ISSN:
- 0009-3130
- Subject:
- Chrysanthemum morifolium; chemical structure; cultivars; glucosides; lignans; nuclear magnetic resonance spectroscopy; silica gel; spectral analysis; stems
- Abstract:
- ... A new neolignan glucoside has been isolated from Chrysanthemum morifolium ‘Baekma’ cultivar through repeated silica gel and octadecyl silica gel (ODS) column chromatographies. On the basis of spectroscopic data including NMR, MS, and IR, the chemical structure of the new neolignan glucoside was determined to be (7S,8S)-7-O-[1′-(4′,5′-dihydroxy-3′-methoxyphenyl)propanol]guaiacylglycerol 4-O-β-D-glu ...
- DOI:
- 10.1007/s10600-019-02760-1
- https://doi.org/10.1007/s10600-019-02760-1
- Author:
- Poolsak Sahakitpichan; Nitirat Chimnoi; Chutima Srinroch; Somsak Ruchirawat; Tripetch Kanchanapoom
- Source:
- Phytochemistry letters 2018 v.26 pp. 30-32
- ISSN:
- 1874-3900
- Subject:
- Wrightia; flavonols; glucosides; lignans; nuclear magnetic resonance spectroscopy; secondary metabolites; spectral analysis
- Abstract:
- ... A new class of secondary metabolites of the family Apocynaceae, benzoxazinoid, was reported for the first time from Wrightia religiosa. A new benzoxazinoid glycoside, (2S)-2-O-β-d-glucopyranosyl-2H-1,4-benzoxazin-3(4H)-one (2) and a new indole diglycoside, indoxyl 3-O-β-d-apiofuranosyl-(1 → 6)-β-d-glucopyranoside (4) were isolated, together with twelve known compounds, including benzoxazinoid glyc ...
- DOI:
- 10.1016/j.phytol.2018.05.012
- https://doi.org/10.1016/j.phytol.2018.05.012
- Author:
- Theofilos Mailis; Helen Skaltsa
- Source:
- Plants 2018 v.7 no.1 pp. -
- ISSN:
- 2223-7747
- Subject:
- Salvia officinalis; acetophenones; aerial parts; caffeic acid; fatty acids; flavonoids; glucosides; lignans; monoterpenoids; nuclear magnetic resonance spectroscopy; secondary metabolites; spectral analysis; triterpene acids; Cyprus
- Abstract:
- ... Twenty compounds were isolated from the aerial parts of Salvia willeana (Holmboe) Hedge, growing wild in Cyprus. These compounds comprise one new and one known acetophenone, one megastigmane glucoside, five phenolic derivatives, two caffeic acid oligomers, three flavonoids, two lignans, two triterpene acids, one monoterpene glucoside, and two fatty acids. The structures of the isolated compounds w ...
- DOI:
- 10.3390/plants7010018
- PubMed:
- 29509707
- PubMed Central:
- PMC5874607
- https://doi.org/10.3390/plants7010018
- Author:
- Md. Abdul Muhit; Kaoru Umehara; Hiroshi Noguchi
- Source:
- Phytochemistry 2018 v.145 pp. 161-167
- ISSN:
- 0031-9422
- Subject:
- Terminalia citrina; breast neoplasms; cell proliferation; estradiol; estrogenic properties; ethyl acetate; glucosides; human cell lines; leaves; lignans; medicinal plants; moieties; neoplasm cells; nuclear magnetic resonance spectroscopy; spectral analysis; stereochemistry; tetrahydrofuran; Bangladesh
- Abstract:
- ... EtOAc extract from the leaves of Terminalia citrina collected in Bangladesh were separated, and seven previously undescribed α-keto tetrahydrofuran lignan glucosides (terminalosides Q to W) were isolated and characterized. NOESY analysis of ¹H NMR spectra and ECD spectroscopic data analysis revealed the absolute stereochemistry of the tetrahydrofuran ring of the isolated constituents as being a (7 ...
- DOI:
- 10.1016/j.phytochem.2017.10.011
- https://doi.org/10.1016/j.phytochem.2017.10.011
- Author:
- Dan-Qi Li; Di Wang; Le Zhou; Ling-Zhi Li; Qing-Bo Liu; Ying-Ying Wu; Jing-Yu Yang; Shao-Jiang Song; Chun-Fu Wu
- Source:
- Journal of Asian natural products research 2017 v.19 no.5 pp. 519-527
- ISSN:
- 1477-2213
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Bupleurum chinense; antioxidant activity; bioactive compounds; cytotoxicity; ethanol; fluorouracil; free radical scavengers; glucosides; inhibitory concentration 50; lignans; neoplasm cells; nuclear magnetic resonance spectroscopy; roots; spectral analysis
- Abstract:
- ... In the search for biologically active compounds from the roots of Bupleurum chinense D C., phytochemical investigation of its ethanol extract led to the isolation and identification of a new 8- O -4′ neolignan glucoside, saikolignanoside A (1), along with eight known lignans (2–9). Their structures were determined on the basis of IR, UV, HRESIMS, and NMR spectroscopic analyses. The antioxidant and ...
- DOI:
- 10.1080/10286020.2016.1234456
- https://doi.org/10.1080/10286020.2016.1234456
- Author:
- Yue-Ting Li; Man-Man Li; Jing Sun; Zhi-Xiang Zhu; Yue-Lin Song; Dao-Ran Pang; Jiao Zheng; Yun-Fang Zhao; Peng-Fei Tu; Jun Li
- Source:
- Natural product research 2017 v.31 no.8 pp. 918-924
- ISSN:
- 1478-6427
- Subject:
- Vitex negundo; glucosides; inhibitory concentration 50; leaves; lignans; nitric oxide; spectral analysis; spectroscopy
- Abstract:
- ... Two new furofuran lignan glucosides, cannabilignin (1) and isocannabilignin (2), together with four known compounds (3 – 6), were isolated from the leaves of Vitex negundo var. cannabifolia . The structures of the isolates were elucidated by analysis of spectroscopic data. Compound 3 exhibited weak inhibition of nitric oxide production in lipopolysaccharide-stimulated BV-2 microglial cells with IC ...
- DOI:
- 10.1080/14786419.2016.1255887
- https://doi.org/10.1080/14786419.2016.1255887
- Author:
- Takahiro Matsumoto; Seikou Nakamura; Souichi Nakashima; Tomoe Ohta; Keiko Ogawa; Masashi Fukaya; Junko Tsukioka; Tomohiro Hasei; Tetsushi Watanabe; Hisashi Matsuda
- Source:
- Phytochemistry 2017 v.137 pp. 101-108
- ISSN:
- 0031-9422
- Subject:
- aerial parts; chemical structure; cytotoxicity; glucosides; lignans; nuclear magnetic resonance spectroscopy; protective effect; spectral analysis; Japan
- Abstract:
- ... Six neolignan glucosides, named isodonosides I–VI, and a megastigmane glucoside named isodonmegastigmane I, were isolated together with 15 known compounds from the methanolic extract of aerial parts of Isodon japonicus cultivated in Tokushima, Japan. The chemical structures of the compounds were elucidated based on their MS and NMR spectroscopic analysis. The absolute configurations of the neolign ...
- DOI:
- 10.1016/j.phytochem.2017.02.007
- https://doi.org/10.1016/j.phytochem.2017.02.007
- Author:
- Jia Chen; Chun-Chao Zhao; Jian-Hua Shao; Ju-Di Fan; Xu-Hua Huang
- Source:
- Chemistry of natural compounds 2017 v.53 no.4 pp. 626-628
- ISSN:
- 0009-3130
- Subject:
- Galium verum; Helicoverpa armigera; Scorpiones; chemical structure; glucosides; insecticidal properties; lignans; mortality; poisoning; scorpion venoms; spectral analysis; stomach; toxicity
- Abstract:
- ... A new lignan glucoside, galiveroside A (1), and seven known compounds (2–8), were isolated from Galium verum L. The structure of 1 was elucidated on the basis of extensive spectroscopic analyses. Compound 1, at the concentration of 5 mg/mL, showed insecticide activity to 3 age cotton bollworm with a mortality of 16.3% through stomach poisoning. When combined with a recombinant scorpion toxin rLqh ...
- DOI:
- 10.1007/s10600-017-2075-3
- https://doi.org/10.1007/s10600-017-2075-3
- Author:
- Jian-Hua Shao; Xue-Wei Zhang; Zi-Ling Dong; Si-Hui Li; Ben-Jie Miao; Ke-Zhi Cheng
- Source:
- Chemistry of natural compounds 2017 v.53 no.6 pp. 1025-1027
- ISSN:
- 0009-3130
- Subject:
- Cyclea; chemical structure; glucosides; lignans; spectral analysis
- Abstract:
- ... A new lignan glucoside 1, along with two known lignans (2, 3), was isolated from Cyclea racemosa Oliv. Its structure was elucidated as (+)-7′-methoxylariciresinol 4-O-β-D-glucopyranoside on the basis of extensive spectroscopic analyses. ...
- DOI:
- 10.1007/s10600-017-2193-y
- https://doi.org/10.1007/s10600-017-2193-y
15. Nine new compounds from the root bark of Lycium chinense and their α-glucosidase inhibitory activity
- Author:
- Ya-Nan Yang; Ya-Wen An; Zhi-Lai Zhan; Jing Xie; Jian-Shuang Jiang; Zi-Ming Feng; Fei Ye; Pei-Cheng Zhang
- Source:
- RSC advances 2017 v.7 no.2 pp. 805-812
- ISSN:
- 2046-2069
- Subject:
- Lycium chinense; acarbose; alpha-glucosidase; bark; cortex; enzyme inhibition; enzyme inhibitors; fruits; glucosides; inhibitory concentration 50; lignans; naphthalene; nuclear magnetic resonance spectroscopy; sesquiterpenoids; shrubs; spectral analysis
- Abstract:
- ... Lycium chinense Mill. is a deciduous shrub in the Solanaceae family that is known for its fruits (Lycii fructus) and root bark (Lycii cortex). In our ongoing search for α-glucosidase inhibitors from the root bark of L. chinense, lyciumflavane A, one new flavane with an unusual benzofuran unit, one new amide possessing a naphthalene skeleton, one new sesquiterpene, three new lignan glucosides, and ...
- DOI:
- 10.1039/c6ra24751b
- https://doi.org/10.1039/c6ra24751b
- Author:
- Serdar Demir; Canan Karaalp; Erdal Bedir
- Source:
- Phytochemistry 2017 v.143 pp. 12-18
- ISSN:
- 0031-9422
- Subject:
- Centaurea; aerial parts; chemical degradation; flavonoids; flora; glucosides; lignans; mass spectrometry; metabolites; nuclear magnetic resonance spectroscopy; sesquiterpenoid lactones; spectral analysis; Turkey (country)
- Abstract:
- ... The genus Centaurea L. (Asteraceae) is represented by 200 taxa in the flora of Turkey and several Centaurea species are used as herbal remedies against different conditions. Previous phytochemical investigations on this genus generally revealed the isolation of sesquiterpene lactones and flavonoid derivatives. In our continuous search on Centaurea genus, a phytochemical study was performed on Cent ...
- DOI:
- 10.1016/j.phytochem.2017.07.002
- https://doi.org/10.1016/j.phytochem.2017.07.002
- Author:
- Yong-Mei Ren; Chang-Qiang Ke; Attila Mándi; Tibor Kurtán; Chunping Tang; Sheng Yao; Yang Ye
- Source:
- Tetrahedron 2017 pp. -
- ISSN:
- 0040-4020
- Subject:
- Vaccinium bracteatum; biochemical pathways; chemical reactions; chemical structure; circular dichroism spectroscopy; glucosides; iridoids; leaves; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
- Abstract:
- ... Two new lignan-iridoid glucoside diesters (2 and 3), together with their putative biosynthetic precursor 10-O-trans-caffeoyl-6α-hydroxyl-dihydromonotropein (1), were characterized from the leaves of Vaccinium bracteatum. Their planar structures and relative configuration were elucidated by spectroscopic measurements and DFT C NMR calculations, and their absolute configurations were determined by t ...
- DOI:
- 10.1016/j.tet.2017.04.040
- https://doi.org/10.1016/j.tet.2017.04.040
- Author:
- Muhit Md. Abdul; Umehara Kaoru; Mori-Yasumoto Kanami; Noguchi Hiroshi
- Source:
- Journal of natural products 2016 v.79 no.5 pp. 1298-1307
- ISSN:
- 1520-6025
- Subject:
- Terminalia; breast neoplasms; cell proliferation; glucosides; humans; leaves; lignans; medicinal plants; nuclear magnetic resonance spectroscopy; spectral analysis
- Abstract:
- ... Extracts from the leaves of the Bangladeshi medicinal plant Terminalia citrina were prepared, and 13 new furofuran lignan glucosides, terminalosides A–K (1–4, 6–12), 2-epiterminaloside D (5), and 6-epiterminaloside K (13), were characterized using various spectroscopic techniques. Twelve of the isolates were found to contain rare tetraoxygenated aryl groups in their structures. Analysis of the NMR ...
- DOI:
- 10.1021/acs.jnatprod.5b01042
- https://doi.org/10.1021/acs.jnatprod.5b01042
- Author:
- Acharawan Panyadee; Poolsak Sahakitpichan; Somsak Ruchirawat; Tripetch Kanchanapoom
- Source:
- Phytochemistry letters 2015 v.11 pp. 215-219
- ISSN:
- 1874-3900
- Subject:
- Bruguiera gymnorhiza; Cotoneaster; glucosides; kaempferol; leaves; lignans; luteolin; myricetin; nuclear magnetic resonance spectroscopy; quercetin; rutin; spectral analysis
- Abstract:
- ... Two new 5-methyl ether flavone glucosides (7,4′,5′-trihydroxy-5,3′-dimethoxyflavone 7-O-β-D-glucopyranoside and 7,4′-dihydroxy-5-methoxyflavone 7-O-β-D-glucopyranoside) were isolated from the leaves of Thai mangrove Bruguiera gymnorrhiza together with 7,3′,4′,5′-tetrahydroxy-5-methoxyflavone, 7,4′,5′-trihydroxy-5,3′-dimethoxyflavone, luteolin 5-methyl ether 7-O-β-D-glucopyranoside, 7,4′-dihydroxy- ...
- DOI:
- 10.1016/j.phytol.2014.12.021
- https://doi.org/10.1016/j.phytol.2014.12.021
- Author:
- Ihsan Calis; Hasan Kirmizibekmez; Tayfun Ersoz; Ali A. Dönmez; Charlotte H. Gotfredsen; Søren R. Jensen
- Source:
- Zeitschrift für Naturforschung 2014 v.60 no.12 pp. 1295-1298
- ISSN:
- 0932-0776
- Subject:
- Phlomis tuberosa; aerial parts; alcohols; glucosides; iridoid glycosides; lignans; luteolin; spectral analysis; verbascoside
- Abstract:
- ... From the aerial parts of Phlomis tuberosa a new iridoid glucoside, chlorotuberoside was isolated together with five known iridoid glucosides, lamalbide, shanzhiside methyl ester, 7-epi-phlomiol (= phloyoside I), sesamoside and 5-deoxysesamoside. Two known phenylethanoid glycosides, forsythoside B, and decaffeoylacteoside, three known neolignan glycosides, dehydrodiconiferyl alcohol 9’-O-β -D-gluco ...
- DOI:
- 10.1515/znb-2005-1214
- https://doi.org/10.1515/znb-2005-1214