Subject: spectral analysis and lignans / Subject term: lignans

1. Anti-hypoxic active constituents from the twigs of Zanthoxylum armatum DC. and their chemotaxonomic significance

Author:: Xiao-Xue Zhai; Xian-Hua Meng; Cheng-Bo Wang; Ya-Min Zhao; Jun-Li Yang
Source:: Biochemical systematics and ecology 2022 v.104 pp. 104480
ISSN:: 0305-1978
Subject:: Zanthoxylum armatum; chemotaxonomy; ecology; lignans; phytochemicals; spectral analysis
Abstract:: ... Phytochemical investigation of the twigs of Zanthoxylum armatum DC. led to the extraction and isolation of twenty-one compounds, including nine phenolic acids (1–9), a steroid (10) and eleven lignans (11–21). The structures of these compounds were elucidated by NMR spectroscopic analysis, and comparison with the reported data. Compounds 1–7, 15, 17, 18, and 21 were first obtained from Z. armatum. ...
DOI:: 10.1016/j.bse.2022.104480
: https://doi.org/10.1016/j.bse.2022.104480

2. Antiviral and Antioxidant Components from the Fruits of Illicium verum Hook.f. (Chinese Star Anise)

Author:: Wen Li; Zhongnan Wu; Yiping Xia; Jinlin Tan; Haiyue Zhao; Si Chen; Yaolan Li; Hongfeng Tang; Guocai Wang; Yubo Zhang
Source:: Journal of agricultural and food chemistry 2022 v.70 no.12 pp. 3697-3707
ISSN:: 1520-5118
Subject:: Illicium verum; Orthomyxoviridae; anise; antioxidants; antiviral properties; circular dichroism spectroscopy; cuisine; cytopathogenicity; electrospray ionization mass spectrometry; fluorescent antibody technique; food chemistry; fruits; lignans; oseltamivir; phenylpropanoids; phytochemicals; spectral analysis; South East Asia
Abstract:: ... Illicium verum Hook.f. (Chinese star anise), a known Chinese traditional spice, is commonly applied in Chinese cuisine and cooking in Southeast Asia. As a kind of medicinal and edible resource, the fruit of I. verum has attracted great attention for its chemical constituents and physiological activities. In this work, the phytochemical study of the fruits of I. verum led to the isolation and ident ...
DOI:: 10.1021/acs.jafc.1c08376
: https://doi.org/10.1021/acs.jafc.1c08376

3. Bioactive neolignans and lignans from the roots of Paeonia lactiflora

Author:: Huan XIA; Jing-Fang ZHANG; Ling-Yan WANG; Gui-Yang XIA; Ya-Nan WANG; Yu-Zhuo WU; Peng-Cheng LIN; Liang XIONG; Sheng LIN
Source:: Chinese journal of natural medicines 2022 v.20 no.3 pp. 210-214
ISSN:: 1875-5364
Subject:: Paeonia lactiflora; X-ray diffraction; carboxylesterase; circular dichroism spectroscopy; enantiomers; humans; lignans; spectral analysis
Abstract:: ... Two new neolignans and one new lignan (1–3) were obtained from the roots of Paeonia lactiflora. Their structures were unambiguously elucidated based on extensive spectroscopic analysis, single-crystal X-ray crystallography, and the calculated and experimental electronic circular dichroism (ECD) spectra. Compound 1 was a racemic mixture and successfully resolved into the anticipated enantiomers via ...
DOI:: 10.1016/S1875-5364(22)60164-X
: https://doi.org/10.1016/S1875-5364(22)60164-X

4. Bis-iridoids and other constituents from Scabiosa semipapposa

Author:: Samia Bendamene; Naima Boutaghane; Charlotte Sayagh; Abdulmagid Alabdul Magid; Zahia Kabouche; Chawki Bensouici; Laurence Voutquenne-Nazabadioko
Source:: Phytochemistry letters 2022 v.49 pp. 202-210
ISSN:: 1874-3900
Subject:: Scabiosa; antioxidant activity; antioxidants; chemotaxonomy; flavonoids; glycosides; iridoids; lignans; mass spectrometry; phenol; spectral analysis
Abstract:: ... Six undescribed bis-iridoids named Semipapposiridoids A–F (1–6) together with seventeen known compounds were obtained from the roots and aerial parts of Scabiosa semipapposa Salzm. ex DC. Among the known compounds, three lignans were isolated for the first time in Scabiosa species, whereas the other known constituents including iridoids, phenol glycosides and flavonoids were previously isolated fr ...
DOI:: 10.1016/j.phytol.2022.04.005
: https://doi.org/10.1016/j.phytol.2022.04.005

5. Chemical and biological studies of Daphniphyllum oldhamii from Hunan Province, China

Author:: Yi Chen; Shou-Mao Shen; Min Yang; Ming-Zhi Su; Xiao-Ming Wang; Yue-Wei Guo
Source:: Phytochemistry 2022 v.199 pp. 113170
ISSN:: 0031-9422
Subject:: Daphniphyllum; X-ray diffraction; lignans; plant biochemistry; spectral analysis; triterpenoids; China
Abstract:: ... The fruits, twigs and leaves of Daphniphyllum oldhamii (Hemsl.) K. Rosenthal, collected from Longshan County, Hunan Province, China, were chemically investigated. Three undescribed daphniphyllum alkaloids, namely longshanoldhamines A‒C, and six known related ones have been isolated from the fruits, whereas two undescribed triterpenoids and one undescribed lignan, along with six known triterpenoids ...
DOI:: 10.1016/j.phytochem.2022.113170
: https://doi.org/10.1016/j.phytochem.2022.113170

6. Chemical constituents from Dracocephalum moldavica L. and their chemotaxonomic significance

Author:: Jiaming Wang; Jinfeng Sun; Mengjie Wang; Huiqiong Cui; Wei Zhou; Gao Li
Source:: Biochemical systematics and ecology 2022 v.102 pp. 104422
ISSN:: 0305-1978
Subject:: Dracocephalum moldavica; chemotaxonomy; ecology; glycosides; lignans; monoterpenoids; norisoprenoids; phytochemicals; spectral analysis; triterpenoids
Abstract:: ... A phytochemical investigation of the aerial parts of Dracocephalum moldavica L. (Lamiaceae) led to the isolation and characterization of 30 compounds, including eight lignans (1–8), seven phenols (9–15), five triterpenoids (16–20), four monoterpenoids (21–24), four glycosides (25–28) and two megastigmanes (29 and 30). The structures of these compounds were determined by spectroscopic data analysis ...
DOI:: 10.1016/j.bse.2022.104422
: https://doi.org/10.1016/j.bse.2022.104422

7. Chemical constituents from Maytenus hookeri

Author:: Nian Jiang; Changyan Yu; Jing Hui; Jianxun Xie; Yuanyuan Wang; Jun Yang; Sanhua Li; Lingjie Meng
Source:: Biochemical systematics and ecology 2022 v.104 pp. 104475
ISSN:: 0305-1978
Subject:: Maytenus; chemotaxonomy; ecology; lignans; phenylpropanoids; phytochemicals; saponins; spectral analysis; triterpenoids
Abstract:: ... A phytochemical investigation on the branches of Maytenus hookeri resulted in the isolation and identification of fourteen compounds, including one new triterpene saponin (1), five phenylpropanoids (2–6), and eight lignans (7–14). The chemical structures of these compounds were determined by comprehensive spectroscopic data analysis, such as UV, IR, 1D/2D NMR, mass spectra, and data from the liter ...
DOI:: 10.1016/j.bse.2022.104475
: https://doi.org/10.1016/j.bse.2022.104475

8. Chemical constituents from Salvinia natans (L.) All. (Salviniaceae) and their chemotaxonomic significance

Author:: Hien Giang Pham; Manh Tuan Ha; Thao Quyen Cao; Ngoc Khanh Vu; Thi Thanh Le; Byung Sun Min
Source:: Biochemical systematics and ecology 2022 v.102 pp. 104410
ISSN:: 0305-1978
Subject:: Salvinia natans; chemotaxonomy; ecology; lignans; norisoprenoids; phenanthrenes; phytochemicals; spectral analysis
Abstract:: ... The phytochemical research on Salvinia natans (L.) All. resulted in the isolation of 11 compounds, subdivided into four steroids (1–4), three megastigmanes (5–7), two lignans (8 and 9), one phenanthrene (10), and one nepetolactone derivative (11). The structures of these compounds were elucidated mainly by NMR spectroscopic analysis and comparison with the published data. All these compounds were ...
DOI:: 10.1016/j.bse.2022.104410
: https://doi.org/10.1016/j.bse.2022.104410

9. Chemical constituents from the aerial parts of Achillea alpina and their chemotaxonomic significance

Author:: Xiuwei Li; Xia Wu; Qiang Guo; Changli Liu; Hucheng Yue; Jiayi Tian; Zongyang Liu; Meng Xiao; Ang Li; Zhongqi Ning; Ke Zan; Xiaoqing Chen
Source:: Biochemical systematics and ecology 2022 v.101 pp. 104381
ISSN:: 0305-1978
Subject:: Achillea; chemotaxonomy; ecology; lignans; phytochemicals; sesquiterpenoids; spectral analysis
Abstract:: ... Phytochemical investigation of the aerial parts of Achillea alpina led to the isolation of sixteen compounds, including six sesquiterpenes (1-6), two polyacetylenic alcohols (7-8), three lignans (9-11), and five fatty acids (12-16). Their structures were identified by spectroscopic analysis of UV, IR, MS and NMR, and in comparison with the those reported data in the references. Among them, five co ...
DOI:: 10.1016/j.bse.2022.104381
: https://doi.org/10.1016/j.bse.2022.104381

10. Chemical constituents from the fruits of Illicium simonsii and their antiviral activity and neuroprotective effect

Author:: Guo-Zhu Su; Mi Li; Xiao-Jing Wang; Ru-Bing Wang; Shuang-Gang Ma; Dan Zhang; Xiao-Liang Wang; Li Li; Yun-Bao Liu; Jing Qu; Yu-Huan Li; Yong Li; Shi-Shan Yu
Source:: Phytochemistry 2022 v.202 pp. 113323
ISSN:: 0031-9422
Subject:: Illicium; X-ray diffraction; antiviral properties; diterpenoids; lignans; neuroprotective effect; plant biochemistry; sesquiterpenoids; spectral analysis; viruses
Abstract:: ... One undescribed diterpenoid illisimonone A, four undescribed sesquiterpenes named (±)-simonones A, simonterpenoids A and B, and two undescribed lignans, illisimonins A and B, along with five known compounds were isolated from the fruits of Illicium simonsii. Their structures were elucidated by extensive spectroscopic data. The absolute configuration of illisimonone A was determined by single-cryst ...
DOI:: 10.1016/j.phytochem.2022.113323
: https://doi.org/10.1016/j.phytochem.2022.113323

11. Chemical constituents from the leaves of Caesalpinia bonduc (L.) Roxb. and their chemotaxonomic significance

Author:: Le Thi Huyen; Vu Hoang Son; Truong Thi Viet Hoa; Luong Thi My Hanh; Seo Yohan; Park SeonJu; Nguyen Xuan Nhiem; Dan Thi Thuy Hang; Phan Van Kiem; Bui Huu Tai
Source:: Biochemical systematics and ecology 2022 v.100 pp. 104376
ISSN:: 0305-1978
Subject:: Caesalpinia bonduc; chemotaxonomy; ecology; flavonoids; lignans; spectral analysis
Abstract:: ... Caesalpinia bonduc (L.) Roxb. is an important herb in Ayurvedic medicines. In this study, five lignans (1–5), two phloroglucinols (6–7), five flavonoids (8–12) and four phenolics (13–16) were identified from the leaves of C. bonduc by comparison with spectroscopic data published in the literature. To the best of our knowledge, all of these identified phytochemicals were reported for the first time ...
DOI:: 10.1016/j.bse.2021.104376
: https://doi.org/10.1016/j.bse.2021.104376

12. Chemical constituents from the roots of Actinidia valvata Dunn

Author:: Changwei Song; Chunbo Yu; Ying Qin; Jing Hui; Yong Zhang; Shengyan Qian; Lin Xu; Yun Liu
Source:: Biochemical systematics and ecology 2022 v.100 pp. 104371
ISSN:: 0305-1978
Subject:: Actinidia; butanol; chemotaxonomy; coumarins; ecology; glycosides; lignans; phenylpropanoids; secondary metabolites; spectral analysis
Abstract:: ... A previous undescribed dihydrobenzofuran neolignan (1), as well as eleven known phenolic derivatives (2–12) were isolated from the n-butanol fraction of the roots of Actinidia valvata Dunn, including five phenylpropanoids (2–6), four phenolic glycosides (7–10) and two coumarins (11–12). The chemical structures of these compounds were identified by means of extensive spectroscopic analysis and comp ...
DOI:: 10.1016/j.bse.2021.104371
: https://doi.org/10.1016/j.bse.2021.104371

13. Ionones and lignans from the fresh roots of Rehmannia glutinosa

Author:: Xu Chen; Yan-gang Cao; Ying-jie Ren; Yan-ling Liu; Xi-ling Fan; Chen He; Xiang-da Li; Xin-yi Ma; Xiao-ke Zheng; Wei-sheng Feng
Source:: Phytochemistry 2022 v.203 pp. 113423
ISSN:: 0031-9422
Subject:: Rehmannia glutinosa; lignans; norisoprenoids; plant biochemistry; spectral analysis
Abstract:: ... Nine undescribed compounds, together with 21 known components, were isolated from the fresh roots of Rehmannia glutinosa. Their structures were elucidated based on spectroscopic data analysis, and the absolute configurations of undescribed compounds were determined by comparison of their calculated and experimental electronic circular dichroic (ECD) spectra and interpretation of their optical rota ...
DOI:: 10.1016/j.phytochem.2022.113423
: https://doi.org/10.1016/j.phytochem.2022.113423

14. Isolation and Characterization of Anti-Inflammatory Lignans from Oenanthe javanica

Author:: Rongrui Wei; Qinge Ma
Source:: Chemistry of natural compounds 2022 v.58 no.3 pp. 407-410
ISSN:: 0009-3130
Subject:: Oenanthe javanica; chemistry; lignans; spectral analysis
Abstract:: ... A new lignan, named 1-phenylpropenoate-4,8′-lignan A (1), and three known lignans (2–4) were isolated from Oenanthe javanica (Blume) DC. for the first time. The structures of compounds 1–4 were determined by extensive spectroscopic data analysis and comparison with reported references. Compounds 1–4 were evaluated for their inhibitory activity against LPS-induced NO production in RAW264.7 cells. A ...
DOI:: 10.1007/s10600-022-03699-6
: https://doi.org/10.1007/s10600-022-03699-6

15. Lignans and sesquiterpenoids from the stems of Schisandra bicolor var. tuberculata

Author:: Shui-Mei Zhang; Kun Hu; Xiao-Nian Li; Han-Dong Sun; Pema-Tenzin Puno
Source:: Natural products and bioprospecting 2022 v.12 no.1 pp. 19
ISSN:: 2192-2195
Subject:: Schisandra; X-ray diffraction; apoptosis; enantiomers; lignans; quantum mechanics; sesquiterpenoids; spectral analysis; tetrahydrofuran
Abstract:: ... A pair of new tetrahydrofuran lignan enantiomers, (±)-schibiculatin A [(±)-1], a new enedione lignan, schibiculatin B (2), two new cadinane-type sesquiterpenoids, schibiculatins C (3) and D (4), along with two known seco-cadinane-type sesquiterpenoids (5 and 6) and seven known miscellaneous lignans (7–13) were isolated from the stems of Schisandra bicolor var. tuberculata. The structures of 1–4 we ...
DOI:: 10.1007/s13659-022-00342-3
: https://doi.org/10.1007/s13659-022-00342-3

16. Lignans and terpenoids from Gaultheria leucocarpa var. yunnanensis and their anti-inflammatory and antioxidant activities

Author:: Ya-Jie Hu; Man-Lan Chen; Dong Liang
Source:: Fitoterapia 2022 v.162 pp. 105293
ISSN:: 0367-326X
Subject:: Gaultheria; antioxidants; diterpenoids; lignans; spectral analysis; triterpenoids
Abstract:: ... Six new compounds, including three lignans (1a, 1b, and 2), two abietane-type diterpenoids (3 and 4), and a triterpenoid (5), together with 13 known compounds (6a, 6b, and 7–17) were isolated from the aerial parts of Gaultheria leucocarpa var. yunnanensis. Their structures were elucidated by analysis of spectroscopic data involving NMR, IR, UV, and HRESIMS. The absolute configurations of lignans w ...
DOI:: 10.1016/j.fitote.2022.105293
: https://doi.org/10.1016/j.fitote.2022.105293

17. A New Geranylated Lignan from Oenanthe javanica and Anti-Inflammatory Activity

Author:: Rongrui Wei; Zhipei Sang; Qinge Ma
Source:: Chemistry of natural compounds 2022 v.58 no.5 pp. 808-811
ISSN:: 0009-3130
Subject:: Oenanthe javanica; anti-inflammatory activity; chemistry; lignans; spectral analysis
Abstract:: ... A new geranylated lignan, named 8′-geranylated lignan A (1), and a known lignan (2) were isolated from Oenanthe javanica (Blume) DC., to our knowledge, for the first time. Compounds 1 and 2 were determined by analyzing their extensive spectral data and comparing them with related references. Compounds 1 and 2 exhibited anti-inflammatory activities with IC₅₀ values of 15.24 ± 0.39 μM and 20.07 ± 0. ...
DOI:: 10.1007/s10600-022-03803-w
: https://doi.org/10.1007/s10600-022-03803-w

18. New lignans and diterpenoid glycosides from the fruits of Xanthium italicum Moretti

Author:: Yu-Tong Li; Jiang Fu; Hai-Qiang Wang; Yong Li; Yun-Bao Liu; Shuang-Gang Ma; Jing Qu; Shi-Shan Yu
Source:: Journal of Asian natural products research 2022 v.24 no.6 pp. 518-527
ISSN:: 1477-2213
Subject:: Xanthium strumarium var. canadense; diterpenoids; glycosides; lignans; research; spectral analysis
Abstract:: ... A pair of new lignans [(+)- 1 and (-)- 1] and three new compounds (2-4), together with a known compound 5, were isolated from the fruits of Xanthium italicum Moretti. The structures of these compounds were determined on the basis of spectroscopic analysis, particularly HR-ESI-MS and 1 D and 2 D NMR. Compounds 2 and 3 showed antinociceptive effects in an acetic acid-induced writhing test in mice wi ...
DOI:: 10.1080/10286020.2021.1938557
: https://doi.org/10.1080/10286020.2021.1938557

19. Procyanidins and Phlobatannins from the Twigs of Rosa multiflora and Their Neuroprotective Activity

Author:: Tae Hyun Lee; Seong-Min Hong; Da Hye Yoon; Sun Yeou Kim; Chung Sub Kim; Kang Ro Lee
Source:: Journal of natural products 2022 v.85 no.4 pp. 917-926
ISSN:: 1520-6025
Subject:: Rosa multiflora; cell lines; derivatization; glioma; glycosides; lignans; mice; nerve growth factor; neuroglia; neuroprotective effect; nitric oxide; procyanidins; spectral analysis; sugars
Abstract:: ... Three new procyanidins (1–3), two new phlobatannins (6 and 7), a new flavan-3,4-diol glycoside (9), and a new neolignan glycoside (10), along with three previously reported compounds (4, 5, and 8) were isolated from the twigs of Rosa multiflora. The chemical structures of the new compounds (1–3, 6, 7, 9, and 10) were characterized by spectroscopic data interpretation, including NMR (¹H and ¹³C NMR ...
DOI:: 10.1021/acs.jnatprod.1c01033
: https://doi.org/10.1021/acs.jnatprod.1c01033

20. Thujasutchins N and O, two new compounds from the stems and roots of Thuja sutchuenensis

Author:: Miaomiao Wang; Luqiong Huo; Hongxin Liu; Liyun Zhao; Zhifang Xu; Haibo Tan; Sheng-Xiang Qiu
Source:: Natural product research 2022 v.36 no.9 pp. 2356-2362
ISSN:: 1478-6427
Subject:: Thuja; X-ray diffraction; cytotoxicity; lignans; research; secondary metabolites; sesquiterpenoids; skeleton; spectral analysis
Abstract:: ... Two novel secondary metabolites, including one thujopsene-type sesquiterpene designated thujasutchin N (1) and one norlignan named thujasutchin O (2) were obtained from the ethanolic extract of the stems and roots of Thuja sutchuenensis. Among them, thujasutchin O (2) represents the first example of lignan sharing a unique carbon-reduced skeleton with novel acetal functionality. Their structures w ...
DOI:: 10.1080/14786419.2020.1836627
: https://doi.org/10.1080/14786419.2020.1836627

21. A new lignan from the stems of Buchanania lucida Blume (Anacardiaceae)

Author:: Nhan Trung Nguyen; Phu Hoang Dang; Hai Xuan Nguyen; Tho Huu Le; Truong Nhat Van Do; Mai Thanh Thi Nguyen
Source:: Natural product research 2022 v.36 no.14 pp. 3737-3740
ISSN:: 1478-6427
Subject:: 4-hydroxybenzoic acid; Buchanania; lignans; research; spectral analysis
Abstract:: ... From the EtOAc-soluble extract of the stems of Buchanania lucida, one new lignan, (+)-(8S,8′S)-5′-methoxy-4,4′-di-O-methylsecoisolariciresinol (1), together with five known compounds (2–6) were isolated. Their structures were elucidated on the basis of NMR spectroscopic interpretation. The absolute configuration of 1 was determined based on the Cotton effects in the ECD spectrum. In the tyrosinase ...
DOI:: 10.1080/14786419.2020.1871341
: https://doi.org/10.1080/14786419.2020.1871341

22. Amino ether analogues of 4,4′-dihydroxy-3-methoxy-6,7′-cyclolignan and their activity against drug-resistant bacteria

Author:: Guillermo Núñez-Mojica; Martha L. Hernández-Carrillo; Francisco G. Avalos-Alanís; Elvira Garza-González; Verónica M. Rivas-Galindo; David A. Silva-Mares; Marc-Antoine Bazin; Pascal Marchand; María del Rayo Camacho-Corona
Source:: Phytochemistry letters 2022 v.50 pp. 57-60
ISSN:: 1874-3900
Subject:: Enterococcus faecium; Larrea tridentata; Mycobacterium tuberculosis; active ingredients; antibacterial properties; drug resistance; lignans; plant biochemistry; spectral analysis
Abstract:: ... Larrea tridentata antibacterial lignan 4,4′-dihydroxy-3-methoxy-6,7′-cyclolignan (1) was derivatized to obtain eleven new amino ether derivatives (2 A-12 C). The structural elucidation of compounds was performed by analysis of 1D- and 2D NMR spectral data and HRESIMS. The antibacterial activity of compounds was determined against nine drug-resistant bacteria and two strains of Mycobacterium tuberc ...
DOI:: 10.1016/j.phytol.2022.05.004
: https://doi.org/10.1016/j.phytol.2022.05.004

23. Aromatic Cadinane Sesquiterpenoids from the Fruiting Bodies of Phellinus pini Block SARS-CoV-2 Spike–ACE2 Interaction

Author:: Xia Li; Jie Gao; Miaomiao Li; Hao Cui; Wei Jiang; Zong-cai Tu; Tao Yuan
Source:: Journal of natural products 2021 v.84 no.8 pp. 2385-2389
ISSN:: 1520-6025
Subject:: COVID-19 infection; Phellinus pini; Severe acute respiratory syndrome coronavirus 2; hydrogen; lignans; pandemic; sesquiterpenoids; spectral analysis
Abstract:: ... The ongoing COVID-19 global pandemic caused by SARS-CoV-2 inspires the development of effective inhibitors to block the SARS-CoV-2 spike–ACE2 interaction. A chemical investigation on the fruiting bodies of Phellinus pini led to the isolation of five aromatic cadinane sesquiterpenoids including four new ones, named piniterpenoids A–D (1–4), as well as three known lignans. Their structures were dete ...
DOI:: 10.1021/acs.jnatprod.1c00426
: https://doi.org/10.1021/acs.jnatprod.1c00426

24. Bassiamide A, a new alkaloid from xero-halophyte Bassia indica Wight.

Author:: Ahmed Othman; Yhiya Amen; Masako Matsumoto; Maki Nagata; Kuniyoshi Shimizu
Source:: Natural product research 2022 v.36 no.14 pp. 3610-3618
ISSN:: 1478-6427
Subject:: alkaloids; lignans; octopamine; research; spectral analysis
Abstract:: ... N-[(3-(3-methyl-1-oxo-butyl)amino)propyl]-3-(3,4-dihydroxyphenyl)prop-2-enamide (7), named ‘Bassiamide A’, a new alkaloid, together with six known compounds including one lignan (1) and five lignanamides (2–6), were isolated from the aerial parts of Bassia indica Wight. The study also reported an optimal separation of a rare occurring R-isomer lignanamide derivative (6) from a natural origin, in a ...
DOI:: 10.1080/14786419.2021.1872572
: https://doi.org/10.1080/14786419.2021.1872572

25. Characteristic constituents with chemotaxonomic significance from the gum resin of Boswelliacarterii

Author:: Zhi-Chao Chen; Fang-You Chen; Lian-Lian Xu; Bao Yang; Yong-Ming Luo
Source:: Biochemical systematics and ecology 2022 v.104 pp. 104478
ISSN:: 0305-1978
Subject:: Boswellia; chemotaxonomy; diterpenoids; ecology; flavonoids; gum resin; lignans; spectral analysis; triterpenoids
Abstract:: ... Chemical investigation on the gum resin of Boswellia carterii afforded 14 compounds, including three triterpenoids (1-3), one nortriterpenoid (4), five cembrane-type macrocyclic diterpenoids (5–9), three prenylaromadendrane-type diterpenoids (10–12), one flavonoid (13), and one lignan (14). The structures of these compounds were established via spectroscopic analysis and comparison of their NMR da ...
DOI:: 10.1016/j.bse.2022.104478
: https://doi.org/10.1016/j.bse.2022.104478

26. Chemical constituents and aldose reductase inhibitory activities of Betula alba bark and leaves

Author:: Tomoki Iguchi; Minpei Kuroda; Nanami Akiyama; Mariko Hashimoto; Yoshihiro Mimaki
Source:: Natural product research 2022 v.36 no.4 pp. 1004-1008
ISSN:: 1478-6427
Subject:: Betula pubescens var. pubescens; aldehyde reductase; bark; flavanones; glucosides; lignans; methyl salicylate; monoterpenoids; research; spectral analysis; triterpenoids
Abstract:: ... Systematic phytochemical investigation of the bark and leaves of Betula alba was independently conducted. A new cyclic diarylheptanoid glucoside (1), five diarylheptanoids (2–6), a phenylethanoid (7), a methyl salicylate glycoside (8), a dihydrobenzofuran glucoside (9), an arylbutanoid glycoside (10), two lignan glycosides (11 and 12), a flavanone glucoside (13), and a triterpene (14) were isolate ...
DOI:: 10.1080/14786419.2020.1839455
: https://doi.org/10.1080/14786419.2020.1839455

27. Chemical constituents from Melodinus cochinchinensis (Lour.) Merr. and their chemotaxonomic significance

Author:: Lin Yang; Jun-Jie He; Xiao-Yan Cui; Ya-Ping Liu; Bei Wang
Source:: Biochemical systematics and ecology 2021 v.95 pp. 104245
ISSN:: 0305-1978
Subject:: Juglans; Melodinus; Rubia cordifolia; anthraquinones; chemotaxonomy; ecology; flavanones; lignans; spectral analysis; triterpenoids
Abstract:: ... A phytochemical investigation on the twigs and leaves of Melodinus cochinchinensis (Lour.) Merr. resulted in the isolation and identification of 22 compounds, including seven sesamin-type lignans (1–7), three pentacyclic triterpenes (8–10), one anthraquinone (11), one flavanone (12), two phenolic compounds (13 and 14), five aspidosperma-type indole alkaloids (15–19), and three eburnan-type indole ...
DOI:: 10.1016/j.bse.2021.104245
: https://doi.org/10.1016/j.bse.2021.104245

28. Chemical constituents from Semiliquidambar chingii and their chemotaxonomic significance

Author:: Jingyi Zhang; Kumaravel Kaliaperumal; Ziyue Liu; Jun Zhang
Source:: Biochemical systematics and ecology 2022 v.100 pp. 104360
ISSN:: 0305-1978
Subject:: Altingia; Liquidambar; chemotaxonomy; coniferyl alcohol; ecology; ellagic acid; flavonoids; glycosides; hybrids; lignans; resveratrol; shikimic acid; spectral analysis; triterpenoids
Abstract:: ... The present study investigated the phytochemical constituents of Semiliquidambar chingii for the first time, resulting in the isolation and characterization of nineteen compounds which were categorized into eight groups as resveratrol derivatives (1–4), triterpenoids (5–10), flavonoids (11–13), phenolic glycosides (14–15), lignan (16), ellagic acid derivative (17), coniferyl alcohol derivative (18 ...
DOI:: 10.1016/j.bse.2021.104360
: https://doi.org/10.1016/j.bse.2021.104360

29. Chemical constituents from the fruits of Vitex rotundifolia and their chemotaxonomic significance

Author:: Yong-Ming Luo; Rui-Zeng Zhang; Fang-You Chen
Source:: Biochemical systematics and ecology 2022 v.103 pp. 104440
ISSN:: 0305-1978
Subject:: Vitex rotundifolia; alkaloids; chemotaxonomy; diterpenoids; ecology; iridoids; lignans; spectral analysis; xanthones
Abstract:: ... Chemical investigation on the fruits of Vitex rotundifolia Linnaeus f. Afforded 19 compounds, including three diterpenoids (1-3), two iridoids (4 and 5), three xanthones (6–8), an alkaloid (9), seven lignans (10–16), and three sesquilignans (17–19). The structures of these compounds were established via spectroscopic analysis and comparison of their NMR data with the literature. Compounds 1, 6–9, ...
DOI:: 10.1016/j.bse.2022.104440
: https://doi.org/10.1016/j.bse.2022.104440

30. Chemical constituents from the roots of Cichorium glandulosum Boiss. et Huet (Asteraceae)

Author:: Ru Wang; Guijuan Zheng; Ting Dang; Pengfei Jin; Jia Yao; Linjie Su; Guangmin Yao; Dongmei Qin
Source:: Biochemical systematics and ecology 2021 v.96 pp. 104261
ISSN:: 0305-1978
Subject:: Cichorium glandulosum; chemotaxonomy; ecology; isoquercitrin; lignans; myricetin; sesquiterpenoid lactones; spectral analysis
Abstract:: ... A phytochemical investigation of the roots extract of Cichorium glandulosum led to the isolation and characterization of fourteen compounds, including five sesquiterpene lactones (1–5), five flavonoids (6–10), and four lignans (11–14). Their structures were determined by spectroscopic data analysis and comparison with the literatures. This is the first report of the crystal data of lactucopicrin ( ...
DOI:: 10.1016/j.bse.2021.104261
: https://doi.org/10.1016/j.bse.2021.104261

31. Chemical constituents of the pericarp of Toona sinensis and their chemotaxonomic significance

Author:: Ying Chen; Feng Wang; Chaoying Ji; Di Liu; Xiaoxiao Liu; Rongshen Wang; Wanzhong Li
Source:: Biochemical systematics and ecology 2022 v.104 pp. 104458
ISSN:: 0305-1978
Subject:: Toona sinensis; chemotaxonomy; ecology; flavonoids; lignans; pericarp; sesquiterpenoids; spectral analysis; sterols; triterpenoids
Abstract:: ... Phytochemical investigation of the pericarp of Toona sinensis (A. Juss.) Roem (Meliaceae) led to the isolation and identification of 33 compounds, namely, 7 apotirucallane-type triterpenoids (1–7), 2 cycloartane-type triterpenoids (8–9), 5 sterols (10–14), 2 sesquiterpenes (15–16), 2 lignans (17–18), 3 flavonoids (19–21), and 12 phenols (22–33). The chemical structures of these compounds were eluc ...
DOI:: 10.1016/j.bse.2022.104458
: https://doi.org/10.1016/j.bse.2022.104458

32. Chevalierinol A and B, two new neolignan sesquiterpenoids from Magnolia chevalieri

Author:: Pham Thi Ninh; Chu Thi Thu Ha; Tran Huy Thai; Nguyen Phuong Hanh; Nguyen Sinh Khang; Nguyen Thi Dung; Ly Thi Thu Hoai; Tran Van Chien; Tran Van Loc; Vo Thi Quynh Nhu; Nguyen The Anh; Trieu Quy Hung; Tran Van Sung; Ho Ngoc Anh; Tran Thi Phuong Thao
Source:: Natural product research 2021 v.35 no.21 pp. 3745-3751
ISSN:: 1478-6427
Subject:: Magnolia; ethyl acetate; lignans; lipopolysaccharides; macrophages; nitric oxide; research; sesquiterpenoids; spectral analysis
Abstract:: ... Two new neolignan sesquiterpenoids, chevalierinol A (1) and chevalierinol B (2), were isolated from the ethyl acetate extract of Magnolia chevalieri leaves, together with twelve known compounds (3–14). Their structures were elucidated by analysis of spectroscopic data including 1D, 2D and mass spectra and compared with the reported data. Compounds 1, 3, 4, 6, 7, 10 were evaluated for their inhibit ...
DOI:: 10.1080/14786419.2020.1736061
: https://doi.org/10.1080/14786419.2020.1736061

33. Dibenzocyclooctadiene lignans from Artemisia sieversiana and their anti-inflammatory activities

Author:: Xu-Dong Zhou; Chao-Xi Chen; Xi-Kang Zheng; Li-Min Gong; Ke-Wu Zeng; Wei Wang; Peng-Fei Tu
Source:: Natural medicines 2021 v.75 no.4 pp. 1014-1020
ISSN:: 1340-3443
Subject:: Artemisia sieversiana; circular dichroism spectroscopy; lignans; lipopolysaccharides; mice; nitric oxide; quercetin; spectral analysis
Abstract:: ... Two previously undescribed dibenzocyclooctadiene lignans, named sieverlignans D–E (1–2), as well as eight known ones (3–10), were isolated from the aerial parts of Artemisia sieversiana. Their structures were elucidated from extensive spectroscopic analysis, including HRMS, NMR and electronic circular dichroism (ECD) experiments. This study is the first to report dibenzocyclooctadiene lignans in t ...
DOI:: 10.1007/s11418-021-01532-y
: https://doi.org/10.1007/s11418-021-01532-y

34. Dibenzocyclooctadiene lignans from the root bark of Schisandra sphenanthera

Author:: Shiqi Huang; Yuanyuan Liu; Yuze Li; Hao Fan; Wenli Huang; Chong Deng; Xiaomei Song; Dongdong Zhang; Wei Wang
Source:: Phytochemistry letters 2021 v.45 pp. 137-141
ISSN:: 1874-3900
Subject:: Schisandra; bark; colorectal neoplasms; cytotoxicity; ethanol; humans; lignans; lung neoplasms; neoplasm cells; plant biochemistry; spectral analysis
Abstract:: ... Two new dibenzocyclooctadiene lignans, schisphenlignan M and N (1 and 2), together with nine known analogues, schisantherin B (3), gomisin G (4), schisantherin D (5), schisantherin A (6), epigomisin O (7), gomisin O (8), (+)-gomisin K3 (9), schisanhenol B (10) and gomisin A (11) were isolated from the 80 % ethanol extract of root bark of Schisandra sphenanthera. Their structures were determined on ...
DOI:: 10.1016/j.phytol.2021.08.015
: https://doi.org/10.1016/j.phytol.2021.08.015

35. Enantiomeric lignans with antineuroinflammatory activities from Mappianthus iodoides

Author:: Feng Hu; Ya-Jie Hu; Bao-Jun Su; Ya-Qi Wang; Hai-Bing Liao; Dong Liang
Source:: Phytochemistry letters 2021 v.42 pp. 18-23
ISSN:: 1874-3900
Subject:: enantiomers; lignans; neuroglia; plant biochemistry; research; spectral analysis; stems
Abstract:: ... Three new pairs of lignan enantiomers (1a/1b‒3a/3b) and two pairs of known lignan enantiomers (4a/4b and 5a/5b) were isolated from the stems of Mappianthus iodoides. The structures of the enantiomers were elucidated by comprehensive spectroscopic analyses. Their absolute configurations were assigned by single-crystal X-ray diffraction analysis as well as comparison of the experimental and calculat ...
DOI:: 10.1016/j.phytol.2021.01.006
: https://doi.org/10.1016/j.phytol.2021.01.006

36. Guaiane-rich phytochemical profile of Centaurea kotschyi subsp. persica (Boiss.) Wagenitz and identification of hypoglycaemic metabolites

Author:: Elena Serino; Giuseppina Chianese; Giorgia Musto; Gökhan Zengin; Daniela Rigano; Mariano Stornaiuolo; Carmen Formisano; Orazio Taglialatela-Scafati
Source:: Phytochemistry 2022 v.199 pp. 113189
ISSN:: 0031-9422
Subject:: Centaurea; chemical constituents of plants; glycemic effect; lignans; matairesinol; metabolites; monoterpenoids; sesquiterpenoid lactones; spectral analysis
Abstract:: ... Phytochemical investigation of the aerial parts obtained from the Turkish plant Centaurea kotschyi subsp. persica led to the isolation of nine sesquiterpene lactones belonging to the guaiane class, including the undescribed kotschyols A and B, a monoterpene lactone (daphnauranin E), four known lignans (matairesinol, matairesinoside, arctiin and arctigenin) and an undescribed dihydrobenzofuran neol ...
DOI:: 10.1016/j.phytochem.2022.113189
: https://doi.org/10.1016/j.phytochem.2022.113189

37. Lignans and monoterpenes from Daphne penicillata Rehd and their chemotaxonomic significance

Author:: Ming-Hao Jiang; Peng Zhao; Wei-Yu Zhou; Xiao-Xiao Huang; Shao-Jiang Song
Source:: Biochemical systematics and ecology 2022 v.105 pp. 104501
ISSN:: 0305-1978
Subject:: Daphne; chemotaxonomy; ecology; lignans; monoterpenoids; phytochemicals; spectral analysis
Abstract:: ... Phytochemical investigation of Daphne penicillata Rehd led to the isolation of twenty-eight compounds, including eighteen lignans (1–18), nine monoterpenes (19–21, 23–28) and one butanolide (22). According to spectroscopic data analysis and comparison with the previously reported literature, their structures were determined. All of these compounds were isolated from D. penicillata for the first ti ...
DOI:: 10.1016/j.bse.2022.104501
: https://doi.org/10.1016/j.bse.2022.104501

38. Lignans with NO inhibitory activity from Tinospora sinensis

Author:: Jun-Sheng ZHANG; De-Feng XU; Xin-Xin CAO; Yin-Yin WANG; Hua ZHANG
Source:: Chinese journal of natural medicines 2021 v.19 no.7 pp. 500-504
ISSN:: 1875-5364
Subject:: Tinospora sinensis; circular dichroism spectroscopy; density functional theory; glucosides; lignans; lipopolysaccharides; macrophages; mice; nitric oxide; spectral analysis
Abstract:: ... Two new lignan glucosides, tinsinlignans A and B (1 and 2), two new oxyneolignans, tinsinlignans C and D (3 and 4), along with one known analogue (5), were isolated from the stems of Tinospora sinensis. The structures of the new compounds were elucidated based on analysis of spectroscopic data, and the absolute configuration of 1 was determined through electronic circular dichroism (ECD) calculati ...
DOI:: 10.1016/S1875-5364(21)60049-3
: https://doi.org/10.1016/S1875-5364(21)60049-3

39. Neolignan and phenylpropanoid compounds from the resin of Styrax tonkinensis

Author:: Feng Wang; Li Zhang; Qing Zhang; Shu-Mei Wang; Zhen-Feng Fang
Source:: Journal of Asian natural products research 2021 v.23 no.6 pp. 527-535
ISSN:: 1477-2213
Subject:: Styrax tonkinensis; cytotoxicity; lignans; neoplasm cells; research; spectral analysis
Abstract:: ... A new neolignan compound, tonkinensisin A (1), and two phenylpropanoid compounds, tonkinensisin B (2) and tonkinensisin C (3), were isolated from the resin of Styrax tonkinensis (Pierre) Craib ex Hartw. The structures of these compounds were determined by spectroscopic analysis, and the relative configurations of compounds 1 and 3 were determined by J-based configuration analysis (JBCA) method. Al ...
DOI:: 10.1080/10286020.2021.1910240
: https://doi.org/10.1080/10286020.2021.1910240

40. Neolignans and Diarylheptanoids with Anti-Inflammatory Activity from the Rhizomes of Alpinia zerumbet

Author:: Yan Zhang; Yuan-Yuan Yu; Fei Peng; Wen-Tao Duan; Chuan-Hai Wu; Hao-Tian Li; Xu-Fu Zhang; Yu-Sheng Shi
Source:: Journal of agricultural and food chemistry 2021 v.69 no.32 pp. 9229-9237
ISSN:: 1520-5118
Subject:: Alpinia zerumbet; anti-inflammatory activity; circular dichroism spectroscopy; density functional theory; ears; edema; enantiomers; ethanol; ethyl acetate; food chemistry; lignans; lipopolysaccharides; medicine; nitric oxide; phytochemicals; skeleton; spectral analysis
Abstract:: ... The dried leaves and rhizomes of Alpinia zerumbet have been traditionally used as food and medicine. Anti-inflammatory activity-guided phytochemical investigation into the rhizomes of A. zerumbet led to the isolation of 17 compounds including 10 neolignans (1–10, 1a, 1b, 2a, 2b, 3a, 3b, 4, and 5 are new compounds) and seven diarylheptanoids (11–17) in which 1–3 were three pairs of enantiomers. 4 w ...
DOI:: 10.1021/acs.jafc.1c02271
: https://doi.org/10.1021/acs.jafc.1c02271

41. Neolignans and amide alkaloids from the stems of Piper kadsura and their neuroprotective activity

Author:: Hui Chen; Ying Zhu; Ya-Lun Zhang; Meng-Nan Zeng; Yan-Gang Cao; Pan-Ting Sun; Bing Cao; Kun Du; Xuan Zhao; Xiao-Wei Wang; Xiao-Ke Zheng; Wei-Sheng Feng
Source:: Phytochemistry 2022 v.203 pp. 113336
ISSN:: 0031-9422
Subject:: Piper kadsura; apoptosis; autophagy; lignans; neuroprotective effect; plant biochemistry; spectral analysis
Abstract:: ... Four undescribed neolignans and three undescribed amide alkaloids, along with twelve known compounds, were isolated from the stems of Piper kadsura (Choisy) Ohwi. The structures of the new compounds were determined by spectroscopic analysis, quantum-chemical calculations, and Mo₂(OAc)₄-induced ECD analysis. The neuroprotective effects of these compounds against Aβ₂₅₋₃₅-induced cell damage in PC12 ...
DOI:: 10.1016/j.phytochem.2022.113336
: https://doi.org/10.1016/j.phytochem.2022.113336

42. Neolignans from Piper betle Have Synergistic Activity against Antibiotic-Resistant Staphylococcus aureus

Author:: Chuan-Yun Xiao; Zhong-Lin Sun; Jiao Huang; Rong-Sheng Li; Jian-Ming He; Simon Gibbons; Dian-Wen Ju; Qing Mu
Source:: Journal of organic chemistry 2021 v.86 no.16 pp. 11072-11085
ISSN:: 1520-6904
Subject:: Piper betle; Staphylococcus aureus; X-ray diffraction; active sites; antibiotic resistance; bacterial growth; ethidium; lignans; norfloxacin; organic chemistry; phytochemicals; spectral analysis; synergism; transporters
Abstract:: ... A phytochemical investigation of an extract of the leaves of Piper betle, guided by a synergistic antibacterial screen, led to the isolation and structural elucidation of 10 new neolignans, Pibeneolignan A–J (1–10), together with 11 known compounds. The structures and absolute configurations of the new compounds were elucidated on the basis of spectroscopic data, single-crystal X-ray diffraction a ...
DOI:: 10.1021/acs.joc.0c02682
: https://doi.org/10.1021/acs.joc.0c02682

43. A New Lignan from the Leaves of Orthosiphon aristatus

Author:: Yu-Xin Yan; Li-Jun Yan; Yong-Chao Wang; Yu-Xiang Bei
Source:: Chemistry of natural compounds 2021 v.57 no.2 pp. 254-256
ISSN:: 0009-3130
Subject:: Orthosiphon aristatus; chemistry; lignans; methanol; spectral analysis
Abstract:: ... Investigation of the methanol extract of the leaves of Orthosiphon aristatus led to the isolation of four compounds. Their structures were elucidated on the basis of spectroscopic evidence and comparison with the literature. Among these compounds, compound 1 is a new lignan, and 2–4 were isolated from this plant for the first time. ...
DOI:: 10.1007/s10600-021-03330-0
: https://doi.org/10.1007/s10600-021-03330-0

44. New phenylpropanoids from the fruits of Xanthium sibiricum and their anti-inflammatory activity

Author:: Zhao Xia; Tian-qi Xu; Hai-xin Zhang; Yi-min Chen; Guang-xiong Zhou
Source:: Natural product research 2022 v.36 no.3 pp. 805-813
ISSN:: 1478-6427
Subject:: Xanthium strumarium; anti-inflammatory activity; cytotoxicity; enantiomers; humans; lignans; macrophages; mice; neoplasm cells; nitric oxide; phenylpropanoids; research; spectral analysis
Abstract:: ... Seven new phenylpropanoids, including two pairs of enantiomers of 8-O-4′-type neolignans, named (±)-xanthiifructins A-B (1a/1b-2a/2b), a pair of simple phenylpropanoid derivatives (±)-xanthiifructins C (3a/3b), and a racemic phenylpropanoid derivative xanthiifructin D (4), together with four known analogues (5-8) were isolated from the fruits of Xanthium sibiricum. Racemic xanthiifructins A-C were ...
DOI:: 10.1080/14786419.2020.1806273
: https://doi.org/10.1080/14786419.2020.1806273

45. Phenolic compounds and triterpenes from the roots of Vaccinium dunalianum Wight and their chemotaxonomic significance

Author:: Bo-Xiao Wu; Xia Zhang; Guo-Lei Zhu; Xiao-Qin Yang; Yun Liu; Ying-Jun Zhang; Ping Zhao
Source:: Biochemical systematics and ecology 2021 v.95 pp. 104228
ISSN:: 0305-1978
Subject:: Vaccinium dunalianum; chemotaxonomy; ecology; flavanols; lignans; phenol; proanthocyanidins; spectral analysis; triterpenoids
Abstract:: ... Eight phenolic compounds, including two catechins (1 and 2), two proanthocyanidins (3 and 4), three lignans (5–7), and one phenol (8), were isolated from roots of Vaccinium dunalianum Wight (Ericaceae), together with two triterpenes (9 and 10). All of them were isolated from the title plant for the first time. Their chemical structures were established based on the extensive MS and NMR spectroscop ...
DOI:: 10.1016/j.bse.2021.104228
: https://doi.org/10.1016/j.bse.2021.104228

46. Phenylpropanoid conjugated iridoids with anti-malarial activity from the leaves of Morinda morindoides

Author:: Yasinjan Hashim; Kazufumi Toume; Shusaku Mizukami; Yue-Wei Ge; Mayumi Taniguchi; Awet Alem Teklemichael; Nguyen Tien Huy; Joseph M. Bodi; Kenji Hirayama; Katsuko Komatsu
Source:: Natural medicines 2021 v.75 no.4 pp. 915-925
ISSN:: 1340-3443
Subject:: Morinda morindoides; Plasmodium falciparum; abscisic acid; adults; brain; cytotoxicity; flavonols; fractionation; glycosides; iridoids; lignans; mice; norisoprenoids; quality control; spectral analysis
Abstract:: ... Two phenylpropanoid-conjugated iridoids, deglucosyl gaertneroside (1) and morindoidin (2), were isolated from the leaves of Morinda morindoides (Rubiaceae) by activity-guided fractionation using an anti-malarial activity assay. The known related iridoids molucidin (3) and prismatomerin (4), two lignans, abscisic acid, two megastigmanes, and two flavonol glycosides were also identified. The structu ...
DOI:: 10.1007/s11418-021-01541-x
: https://doi.org/10.1007/s11418-021-01541-x

47. Phytochemical and chemotaxonomic studies on Phyllodium pulchellum (Leguminosae)

Author:: Fei-Long Chen; Hai-Shan Zhang; Ji Yang; Ling Chai; Ming Zhong; Buming Liu; Jiantong Yuan; Zhi-Hong Jiang; Guo-Yuan Zhu
Source:: Biochemical systematics and ecology 2021 v.95 pp. 104243
ISSN:: 0305-1978
Subject:: Phyllodium; aerial parts; chemotaxonomy; ecology; flavonoids; lignans; spectral analysis
Abstract:: ... A phytochemical investigation on the aerial part of Phyllodium pulchellum led to the isolation of 16 compounds including five flavonoids (1–5), three lignans (6–8), four indole alkaloids (9–12), and four other-type compounds (13–16). Their structures were elucidated by their spectroscopic data analysis. Among them, 12 compounds (1, 2, 4–9, and 11–14) are reported from the genus Phyllodium for the ...
DOI:: 10.1016/j.bse.2021.104243
: https://doi.org/10.1016/j.bse.2021.104243

48. Potential inhibitors of microglial activation from the roots of Vernicia montana Lour

Author:: Yingjie Wang; Gang Chen; Qingqi Meng; Xiaohu Yao; Yang Li; Honglin Cao; Bin Lin; Yue Hou; Di Zhou; Ning Li
Source:: Phytochemistry 2022 v.194 pp. 113019
ISSN:: 0031-9422
Subject:: Vernicia; lignans; neuroglia; nitric oxide; phytochemicals; spectral analysis; terpenoids
Abstract:: ... During our continuous investigation of natural, herbal inhibitors of microglial over-activation in the Euphorbiaceae family, two plants of the Vernicia genus showed remarkable inhibitory effects on nitric oxide (NO) production in over-activated microglia. In this study, bioactivity-guided phytochemical research on the active fraction of the roots of V. montana was carried out. As a result, seven u ...
DOI:: 10.1016/j.phytochem.2021.113019
: https://doi.org/10.1016/j.phytochem.2021.113019

49. Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities

Author:: Joseph Sakah Kaunda; Xu-Jie Qin; Hong-Tao Zhu; Dong Wang; Chong-Ren Yang; Ying-Jun Zhang
Source:: Phytochemistry 2021 v.184 pp. 112656
ISSN:: 0031-9422
Subject:: Solanum violaceum; Staphylococcus aureus; acid hydrolysis; antibacterial properties; apoptosis; cytotoxicity; diterpenoids; dose response; fruits; glycoalkaloids; human cell lines; lignans; moieties; plant biochemistry; saponins; skeleton; spectral analysis; sugars
Abstract:: ... Three previously undescribed pyridyl-steroidal glycoalkaloids, solanindiosides A‒C, one rare 23S,26R-hydroxylated spirostanoid saponin, and two steroidal alkaloid aglycones, solanindins A and B, derived from the acid hydrolysis of solanindiosides A‒C, were isolated from the fruits of Solanum violaceum, together with five known analogues, including two rare steroidal glycosides, two lignans and a d ...
DOI:: 10.1016/j.phytochem.2021.112656
: https://doi.org/10.1016/j.phytochem.2021.112656

50. Two New Lignans from the Fresh Bark of Ailanthus altissima

Author:: Tian-Hui Zhu; Yu-Fang Wang; Tao Jiang; Li-Kang Zhao; He Mi; Yan-Nan Ji; Francoise Sauriol; Yi-Bing Wu; Yu-Cheng Gu; Mei Dong; Zhi-Yu Ni
Source:: Chemistry of natural compounds 2021 v.57 no.3 pp. 422-424
ISSN:: 0009-3130
Subject:: Ailanthus altissima; bark; chemistry; lignans; mass spectrometry; spectral analysis
Abstract:: ... Two new lignans (1, 2) were isolated from the fresh bark of Ailanthus altissima. The structures were elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR techniques and high-resolution mass spectrometry. ...
DOI:: 10.1007/s10600-021-03379-x
: https://doi.org/10.1007/s10600-021-03379-x

51. Two new ditetrahydrofuran lignans from Artemisia sieversiana

Author:: Xu-Dong Zhou; Xiang-Wei Xu; Lun-Yong Shi; Sheng-Huang Chen; Ke-Wu Zeng; Peng-Fei Tu
Source:: Natural product research 2021 v.35 no.21 pp. 3528-3534
ISSN:: 1478-6427
Subject:: Artemisia sieversiana; circular dichroism spectroscopy; lignans; lipopolysaccharides; mice; nitric oxide; quercetin; research; spectral analysis
Abstract:: ... Two new ditetrahydrofuran lignans, named sieverlignans A and B (1 and 2), together with six known ones (3–8), were isolated from the aerial parts of Artemisia sieversiana. Their structures were established on the basis of spectroscopic analysis including HRMS, NMR spectra and circular dichroism experiments. All the compounds were evaluated for their anti-neuroinflammatory effects on the lipopolysa ...
DOI:: 10.1080/14786419.2020.1712384
: https://doi.org/10.1080/14786419.2020.1712384

52. Tyrosinase Inhibitors Derived from Chemical Constituents of Dianella ensifolia

Author:: Yu-Chang Chen; Sheng-Han Su; Jheng-Cian Huang; Che-Yi Chao; Ping-Jyun Sung; Yih-Fung Chen; Horng-Huey Ko; Yueh-Hsiung Kuo
Source:: Plants 2022 v.11 no.16 pp. -
ISSN:: 2223-7747
Subject:: Dianella; carotenoids; chalcones; diterpenoids; flavanones; flavones; herbal medicines; lignans; monoterpenoids; mushrooms; phenylpropanoids; rhizomes; spectral analysis; triterpenoids; Asia; Australia
Abstract:: ... Dianella ensifolia is a perennial herb with thickened rhizome and is widely distributed in tropical and subtropical regions of Asia, Australia, and the Pacific islands. This plant has the potential to be used as a source of herbal medicine. This study investigated further phytochemistry and tyrosinase inhibitory effect of some constituents isolated from D. ensifolia. Four new flavans, (2S)-4’-hydr ...
DOI:: 10.3390/plants11162142
: https://doi.org/10.3390/plants11162142

53. A new 7′,9-epoxylignan from the stems of Salacia chinensis

Author:: Nhan T. Nguyen; Truc T. T. Duong; Phu H. Dang; Hai X. Nguyen; Tho H. Le; Truong N. V. Do; Thinh D. Le; Tu H. Tran; Mai T. T. Nguyen
Source:: Natural product research 2022 v.36 no.15 pp. 4026-4030
ISSN:: 1478-6427
Subject:: Salacia chinensis; lignans; research; spectral analysis
Abstract:: ... Bioactivity-guided isolation of the CHCl₃-soluble fraction of the stems of Salacia chinensis L. (Celastraceae) was carried out to obtain a new 7′,9-epoxylignan (1) and three 7,9′:7′,9-diepoxylignans (2–4). The absolute configuration of 1 was elucidated based on NMR and ECD spectroscopic data interpretation. All isolated lignans showed intermediate α-glucosidase inhibitory activity with the IC₅₀ va ...
DOI:: 10.1080/14786419.2021.1900178
: https://doi.org/10.1080/14786419.2021.1900178

54. Amides and lignans from Solanum lyratum

Author:: Xiaowen Wang; Yue Zhao; Xueqi Dong; Xile Wu; Hai-Yang Yu; Li-Hua Zhang; Lifeng Han; Yi Zhang; Tao Wang; Hong-Hua Wu
Source:: Phytochemistry letters 2021 v.45 pp. 25-29
ISSN:: 1874-3900
Subject:: Solanum lyratum; acrylamides; ethanol; flavonoids; lignans; liver neoplasms; sesquiterpenoids; spectral analysis; toxicity testing
Abstract:: ... Sixteen non-steroidal compounds including four amides, six lignans, two sesquiterpenoids and three flavonoids, were isolated from the 80 % ethanol extract of whole plants of Solanum lyratum Thunb. Their structures were assigned based on analyses of extensive spectroscopic data (including MS, 1D/2D NMR and ORD) or comparisons of the NMR data with those reported. Among them, there were a new lignan ...
DOI:: 10.1016/j.phytol.2021.07.002
: https://doi.org/10.1016/j.phytol.2021.07.002

55. Anti-Inflamatory Activity of Neolignan Compound Isolated from the Roots of Saururus chinensis

Author:: Sae-Rom Yoo; Hyekyung Ha; Hyeun-Kyoo Shin; Chang-Seob Seo
Source:: Plants 2020 v.9 no.8 pp. -
ISSN:: 2223-7747
Subject:: Saururus chinensis; animal models; anti-inflammatory activity; cell lines; chromatography; circular dichroism spectroscopy; ethyl acetate; fractionation; immunoblotting; inducible nitric oxide synthase; lignans; lipopolysaccharides; macrophages; mass spectrometry; methanol; mice; nitric oxide; nuclear magnetic resonance spectroscopy; prostaglandin synthase; prostaglandins; roots; silica gel; solvents; spectral analysis; China; Japan; Korean Peninsula
Abstract:: ... Saururus chinensis (Lour.) Baill. is a perennial herb and grows in Korea, China, and Japan. Interestingly, (7S,8S)-Δ⁸′-3,4-methylenedioxy-3′,5,5′-trimethoxy-7-monoacetate-8.O.4′-neolignan (MTMN), one of the active neolignans, was first isolated from the roots of Saururus chinensis. The compound was screened for anti-inflammatory activity using a RAW264.7 murine macrophage cell line. The dried root ...
DOI:: 10.3390/plants9080932
: https://doi.org/10.3390/plants9080932

56. Anti-β-amyloid aggregation activity of enantiomeric furolactone-type lignans from Archidendron clypearia (Jack) I.C.N.

Author:: Yu-Xi Wang; Bin Lin; Le Zhou; Zhi-Yang Yan; Han Zhang; Xiao-Xiao Huang; Shao-Jiang Song
Source:: Natural product research 2020 v.34 no.4 pp. 456-463
ISSN:: 1478-6427
Subject:: Archidendron; branches; circular dichroism spectroscopy; computer simulation; enantiomers; high performance liquid chromatography; leaves; ligands; lignans; molecular dynamics; phytochemicals; spectral analysis
Abstract:: ... The phytochemical investigation on the twigs and leaves of Archidendron clypearia (Jack) I.C.N. led to the isolation of three pairs of furolactone-type lignans enantiomers, including a pair of new compounds (1R,5S,6S)-Kachiranol (1a) and (1S,5R,6R)-Kachiranol (1b) and four known compounds (2a/2b and 3a/3b). Separation of the furolactone-type lignans enantiomeric mixtures was achieved using chiral ...
DOI:: 10.1080/14786419.2018.1488705
: https://doi.org/10.1080/14786419.2018.1488705

57. Antiproliferative constituents from the aerial parts of Chrysophthalmum montanum (DC.) Boiss

Author:: Fatma Ayaz; Esra Emerce; Nezhun Gören; İhsan Çalış; Mujeeb Ur Rehman; M. Iqbal Choudhary; Nurgün Küçükboyacı
Source:: Phytochemistry letters 2020 v.36 pp. 173-182
ISSN:: 1874-3900
Subject:: Chrysophthalmum; acetates; aerial parts; antineoplastic agents; cell growth; cell viability; cytotoxicity; flavonoids; human cell lines; human diseases; infrared spectroscopy; isomers; lignans; lungs; neoplasm cells; neoplasms; nuclear magnetic resonance spectroscopy; sesquiterpenoid lactones; spectral analysis; triterpenoids
Abstract:: ... Three undescribed sesquiterpene lactones (1-3), 1β,4β-dihydroxy-guaia-10(14),11(13)-dien-8α,12-olide (1), 4α, 6α-dihydroxy-9β,10β-epoxy-1βH-guaia-11(13)-en-8α,12-olide (2), and 4α,9β-dihydroxy-6α-acetoxy-1βH-guaia-10(14),11(13)-dien-8α,12-olide (3), as well as a known sesquiterpene lactone, (4α,5α,8β,10α)-4,10-dihydroxy-1,11(13)-guaiadien-12,8-olide (4), along with a lignan, pinoresinol (5), a fla ...
DOI:: 10.1016/j.phytol.2020.01.003
: https://doi.org/10.1016/j.phytol.2020.01.003

58. Aromatic compounds from Endocomia macrocoma

Author:: Fang Kuang; Ying Liu; Ye-Gao Chen; Rui Zhan
Source:: Natural product research 2020 v.34 no.3 pp. 390-397
ISSN:: 1478-6427
Subject:: Macrocoma; antineoplastic activity; branches; cytotoxicity; human diseases; leaves; lignans; neoplasms; spectral analysis
Abstract:: ... Twenty-seven compounds, including a new diarypropane and two new lignans were isolated from the twigs and leaves of Endocomia macrocoma. Their structures were elucidated by spectroscopic analysis. Cytotoxicity evaluation of the new compounds against five human tumor lines showed no inhibitory effects. ...
DOI:: 10.1080/14786419.2018.1534851
: https://doi.org/10.1080/14786419.2018.1534851

59. Bioactive constituents of Lindernia crustacea and its anti-EBV effect via Rta expression inhibition in the viral lytic cycle

Author:: Yu-Chi Tsai; Judit Hohmann; Mohamed El-Shazly; Li-Kwan Chang; Balázs Dankó; Norbert Kúsz; Chi-Ting Hsieh; Attila Hunyadi; Fang-Rong Chang
Source:: Journal of ethnopharmacology 2020 v.250 pp. 112493
ISSN:: 0378-8741
Subject:: Crustacea; Lindernia; Scrophulariaceae; anthraquinones; antiviral properties; bioactive compounds; cell lines; chromatography; cinnamic acid; diterpenoids; ethyl acetate; flavonoids; glycerol; glycosides; lignans; neoplasm cells; norisoprenoids; phenylethyl alcohol; solvents; spectral analysis; traditional medicine; viruses
Abstract:: ... Lindernia crustacea (L.) F.Muell. (Scrophulariaceae) was selected for phytochemical investigation owing to its traditional use against human herpes virus infection and its anti-Epstein–Barr virus (EBV) effect.The present study focused on the phytochemical investigation of L. crustacea including the isolation and structure determination of its biologically active compounds. Compounds with anti-EBV ...
DOI:: 10.1016/j.jep.2019.112493
: https://doi.org/10.1016/j.jep.2019.112493

60. Bioactive tetrahydrofuran lignans from roots, stems, leaves and twigs of Anogeissus rivularis

Author:: Wannee Sukbangnop; Anowar Hosen; Sakchai Hongthong; Chutima Kuhakarn; Patoomratana Tuchinda; Suppisak Chaturonrutsamee; Sariyarach Thanasansurapong; Radeekorn Akkarawongsapat; Jitra Limthongkul; Chanita Napaswad; Arthit Chairoungdua; Kanoknetr Suksen; Narong Nuntasaen; Vichai Reutrakul
Source:: Fitoterapia 2021 v.151 pp. 104885
ISSN:: 0367-326X
Subject:: Anogeissus; RNA-directed DNA polymerase; cell lines; cytotoxicity; giant cells; lignans; spectral analysis; tetrahydrofuran; viruses
Abstract:: ... Four previously undescribed tetrahydrofuran lignans, named anorisols A−D (1–4) and fourteen known compounds (5–18) were isolated from the roots, stems, leaves and twigs of Anogeissus rivularis. The chemical structures were elucidated on the basis of their spectroscopic data and by comparison with the literature data. The absolute configurations of 1–4 were established by comparison of the experime ...
DOI:: 10.1016/j.fitote.2021.104885
: https://doi.org/10.1016/j.fitote.2021.104885

61. Catechins and lignan from the flower buds of Rosa chinensis Jacq.

Author:: Ying Liu; Zhao Lu; Mei Wang; Yang Chen; Rui Zhan; Li-Dong Shao; Ye-Gao Chen
Source:: Phytochemistry letters 2020 v.38 pp. 46-48
ISSN:: 1874-3900
Subject:: Rosa chinensis; acetone; assays; cell lines; cytotoxicity; extracts; flavanols; flower buds; lignans; neoplasm cells; spectral analysis
Abstract:: ... Five catechins (1-5) including a new compound rosacatechins A (1) and a new natural product (2), along with a lignan (6) were isolated from 70% aqueous acetone extracts of the flower buds of Rosa chinensis Jacq. Their structures were elucidated by extensive spectroscopic analysis. No cytotoxicity was detected on the anti-proliferative assay of these compounds against five cancer cell lines. ...
DOI:: 10.1016/j.phytol.2020.05.004
: https://doi.org/10.1016/j.phytol.2020.05.004

62. Chemical constituents from Ailanthus altissima (Mill.) Swingle and chemotaxonomic significance

Author:: Ding-Ding Zhang; Ming Bai; Zhi-Yang Yan; Xiao-Xiao Huang; Shao-Jiang Song
Source:: Biochemical systematics and ecology 2020 v.93 pp. 104174
ISSN:: 0305-1978
Subject:: Ailanthus altissima; biosynthesis; chalcone; chemical composition; chemotaxonomy; coumarins; lignans; nuclear magnetic resonance spectroscopy; population distribution; spectral analysis
Abstract:: ... Sixteen compounds were isolated from the root barks of Ailanthus altissima (Mill.) Swingle, including thirteen lignans (1–13), two coumarins (14–15), and one chalcone (16). This is the first report on the occurrence of compounds 1–16 in the genus Ailanthus. Their structures were elucidated on the basis of NMR spectroscopic data. The plant distribution network of all isolated compounds was describe ...
DOI:: 10.1016/j.bse.2020.104174
: https://doi.org/10.1016/j.bse.2020.104174

63. Chemical constituents from Anemone vitifolia Buch.-Ham. (Ranunculaceae)

Author:: Lin-Yun Mou; Min Wei; Hai-Yan Wu; Jian-Long Li; Gan-Peng Li
Source:: Biochemical systematics and ecology 2020 v.92 pp. 104123
ISSN:: 0305-1978
Subject:: Ranunculaceae; benzoic acid; chemical composition; chemotaxonomy; lactones; lignans; metabolites; phytochemicals; spectral analysis; succinic acid
Abstract:: ... A phytochemical investigation of Anemone vitifolia (Buch.-Ham.) led to the isolation of twelve compounds, including six lignans (1–6), four benzoic acid esters (7–10), one norsesquiterpenoid (11) and one lactone (12). The structures of these metabolites were established on the basis of detailed spectroscopic analysis, as well as comparisons with the data available in the literature. Among them, co ...
DOI:: 10.1016/j.bse.2020.104123
: https://doi.org/10.1016/j.bse.2020.104123

64. Chemical constituents from Hovenia dulcis Thunb. And their chemotaxonomic significance

Author:: Mei-Chen Li; Chao-Jie Xie; Cai-Wen Meng; Yun-Qiang Zhang; Jin-Gou Gao; Wei-Hua Wang; Jian Yu Liu; Yong Nan Xu
Source:: Biochemical systematics and ecology 2021 v.94 pp. 104214
ISSN:: 0305-1978
Subject:: Hovenia dulcis; benzoic acid; cerebrosides; chemotaxonomy; ecology; flavonoids; fruits; lignans; phenylpropanoids; sesquiterpenoids; spectral analysis; sterols; triterpenoids
Abstract:: ... Phytochemical investigations on the fruit stalks and seeds of the plant Hovenia dulcis Thunb. led to the isolation of twenty-one compounds, including three triterpenes (1–3), two sterols (4–5), five flavonoids (6–10), two sesquiterpenes (11–12), one lignan (13), two phenylpropanoids (14–15), four benzoic acid derivatives (16–19), one acid amide (20) and one cerebroside (21). The structures of thes ...
DOI:: 10.1016/j.bse.2020.104214
: https://doi.org/10.1016/j.bse.2020.104214

65. Chemical constituents from Laggera pterodonta and their anti-inflammatory activities in vitro

Author:: Yan-Qing Xie; Xin-Ye Du; Dan Liu; Xuan-Qin Chen; Rong-Tao Li; Zhi-Jun Zhang
Source:: Phytochemistry letters 2021 v.43 pp. 126-129
ISSN:: 1874-3900
Subject:: Laggera; flavonoids; lignans; macrophages; norisoprenoids; sesquiterpenoids; spectral analysis
Abstract:: ... A phytochemical investigation on the aerial parts of Laggera pterodonta resulted in the isolation and identification of 23 compounds, including twelve sesquiterpenoids (1–12), two norisoprenoids (13, 14), three alkaloids (15-17), one lignan (18), and five flavonoids (19-23). Among them, norpterodonols A (1) and B (2) are two undescribed norsesquiterpenoid derivatives. Their structures were establi ...
DOI:: 10.1016/j.phytol.2021.04.001
: https://doi.org/10.1016/j.phytol.2021.04.001

66. Chemical constituents from Phlomis bovei Noë and their chemotaxonomic significance

Author:: Walid Khitri; Dalila Smati; Anne-Claire Mitaine-Offer; Thomas Paululat; Marie-Aleth Lacaille-Dubois
Source:: Biochemical systematics and ecology 2020 v.91 pp. 104054
ISSN:: 0305-1978
Subject:: Phlomis; carbon; chemical composition; chemotaxonomy; glucosides; iridoids; leaves; lignans; mass spectrometry; metabolites; norisoprenoids; nuclear magnetic resonance spectroscopy; phenylpropanoids; phytochemicals; roots; spectral analysis; stable isotopes
Abstract:: ... A phytochemical investigation of the leaves and roots of Phlomis bovei Noë (Lamiaceae) led to the isolation of sixteen compounds, including iridoids (1, 2, 3), megastigmanes (4, 5), phenylpropanoids (6, 7, 8, 9, 10), lignans (11, 12, 13, 14), a nortriterpene (15), and a phenyl glucoside (16). Compounds (1, 2, 4, 5, 6, 10) were obtained from the leaves and compounds (1, 2, 3, 7, 8, 9, 11, 12, 13, 1 ...
DOI:: 10.1016/j.bse.2020.104054
: https://doi.org/10.1016/j.bse.2020.104054

67. Chemical constituents from the fruits of Solanum incanum L

Author:: Joseph Sakah Kaunda; Ying-Jun Zhang
Source:: Biochemical systematics and ecology 2020 v.90 pp. 104031
ISSN:: 0305-1978
Subject:: Solanum incanum; chemical composition; chemotaxonomy; coumarin; fruits; glucosides; glycoalkaloids; lignans; monoterpenoids; nuclear magnetic resonance spectroscopy; phytochemicals; spectral analysis
Abstract:: ... Phytochemical investigation of the fruits of Solanum incanum L. resulted in the isolation of nine compounds, including three steroidal glycoalkaloids (1-3), two neolignans (4–5), two simple phenolics (6–7), one monoterpene glycoside (8), and one coumarin glucoside (9). The structure elucidation of isolated compounds was determined based on NMR and mass spectral data. Compounds 4 and 9 were isolate ...
DOI:: 10.1016/j.bse.2020.104031
: https://doi.org/10.1016/j.bse.2020.104031

68. Chemical constituents from the leaves of Lyonia ovalifolia var. hebecarpa

Author:: Hanqi Zhang; Xiaofeng Zheng; Guijuan Zheng; Yang Teng; Junfei Zhou; Guangmin Yao
Source:: Biochemical systematics and ecology 2020 v.92 pp. 104129
ISSN:: 0305-1978
Subject:: Hebecarpa; Lyonia ovalifolia; X-ray diffraction; chemical composition; chemotaxonomy; diterpenoids; iridoids; leaves; lignans; monoterpenoids; phenylpropanoids; phytochemicals; sesquiterpenoids; spectral analysis
Abstract:: ... A phytochemical investigation of the leaves of Lyonia ovalifolia var. hebecarpa (Franch. ex F.B. Forbes & Hemsl.) Chun (Ericaceae) led to the isolation of 22 compounds, including eight diterpenoids (1–8), two sesquiterpenoids (9 and 10), two monoterpenoids (11 and 12), two iridoids (13 and 14), four phenylpropanoids (15–18), and four lignans (19–22). Their structures were determined by spectroscop ...
DOI:: 10.1016/j.bse.2020.104129
: https://doi.org/10.1016/j.bse.2020.104129

69. Cytotoxic lignans from fruits of Cleistanthus tonkinensis

Author:: Lam Hong Nguyen; Van Nam Vu; Dao Phi Thi; Viet Hung Tran; Marc Litaudon; Fanny Roussi; Van Hung Nguyen; Van Minh Chau; Huong Doan Thi Mai; Van Cuong Pham
Source:: Fitoterapia 2020 v.140 pp. 104432
ISSN:: 0367-326X
Subject:: Cleistanthus; Euphorbiaceae; circular dichroism spectroscopy; cytotoxicity; fruits; human cell lines; lignans; mass spectrometry; medicinal plants; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:: ... Seven new lignans, cleistonkinins A– E (1–5), cleistonkisides A and B (6–7) were isolated from the fruits of Cleistanthus tonkinensis (Euphorbiaceae), together with five known aryltetralin lignans, cleisindoside B (8), cleistantoxin (9), cleisindoside D (10), neocleistantoxin (11) and polygamain (12). Their structures were established from spectral analysis, including mass spectrometry and 2D-NMR. ...
DOI:: 10.1016/j.fitote.2019.104432
: https://doi.org/10.1016/j.fitote.2019.104432

70. Extractives elucidation of Taiwania cryptomerioides sapwood

Author:: Nai-Wen Tsao; Shih-Chang Chien; Yueh-Hsiung Kuo; Sheng-Yang Wang
Source:: Journal of wood science 2021 v.67 no.1 pp. 16
ISSN:: 1435-0211
Subject:: Mesozoic era; Taiwania cryptomerioides; biosynthesis; color; heartwood; indigenous species; lignans; plant biochemistry; sapwood; sesquiterpenoids; spectral analysis; wood; Taiwan
Abstract:: ... Taiwania (Taiwania cryptomerioides Hayata) has long been regarded as a living fossil from the Tertiary period of Mesozoic Era for its distinguished yellowish-red color with purplish-pink streaks presented in its heartwood. With this elegant appearance that matches the color “red” for good fortune in the Taiwanese culture, Taiwania is supposed to be a popular wood in Taiwan where it is a native spe ...
DOI:: 10.1186/s10086-021-01947-x
: https://doi.org/10.1186/s10086-021-01947-x

71. Identification of neolignans with PCSK9 downregulatory and LDLR upregulatory activities from Penthorum chinense and the potential in cholesterol uptake by transcriptional regulation of LDLR via SREBP2

Author:: Hee-Sung Chae; Pisey Pel; Jinwoo Cho; Young-Mi Kim; Chae-Yeong An; Jungmoo Huh; Young Hee Choi; Jinwoong Kim; Young-Won Chin
Source:: Journal of ethnopharmacology 2021 v.278 pp. 114265
ISSN:: 0378-8741
Subject:: Penthorum chinense; Western blotting; active ingredients; cholecystitis; chromatography; gene expression; genes; hepatitis A; hepatocytes; jaundice; lignans; liver; low density lipoprotein cholesterol; methanol; methyl gallate; perchlorates; protein synthesis; protein-protein interactions; quantitative polymerase chain reaction; spectral analysis; subtilisin; traditional medicine; transcription (genetics); transcription factors; East Asia
Abstract:: ... Penthorum chinense has been used in East Asia for the treatment of cholecystitis, infectious hepatitis, jaundice and to treat liver problems. Recent evidences provided the potential for the clinical use of P. chinense in the treatment of metabolic disease.Aim of the study: Based on the traditional use and recent evidences, we investigated the effects of constituents from P. chinense with modulatio ...
DOI:: 10.1016/j.jep.2021.114265
: https://doi.org/10.1016/j.jep.2021.114265

72. Kalshiolin A, new lignan from Kalimeris shimadai

Author:: Guo-Kai Wang; Wen-Fang Jin; Nan Zhang; Gang Wang; Yung-Yi Cheng; Susan L. Morris-Natschke; Masuo Goto; Zhong-Yu Zhou; Jin-Song Liu; Kuo-Hsiung Lee
Source:: Journal of Asian natural products research 2020 v.22 no.5 pp. 489-495
ISSN:: 1477-2213
Subject:: cytotoxicity; inhibitory concentration 50; lignans; medicine; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:: ... The Asian plant Kalimeris shimadai has been used as food and ethnologic medicine for over a thousand years. In this study, we isolated and identified one new lignan, kalshiolin A (1), and 12 known lignans (2–13). The structures were characterized by the comprehensive analyses of spectroscopic data (HR-ESI-MS, IR, 1D, and 2D-NMR) and the absolute configuration of 1 was determined from ECD calculati ...
DOI:: 10.1080/10286020.2019.1592164
PubMed:: 31190564
PubMed Central:: PMC6908768
: https://doi.org/10.1080/10286020.2019.1592164

73. Lignans and Neolignans with Antioxidant and Human Cancer Cell Proliferation Inhibitory Activities from Cinnamomum bejolghota Confirm Its Functional Food Property

Author:: Li Rao; Yun-Xia You; Yu Su; Yue Fan; Yu Liu; Qian He; Yi Chen; Jie Meng; Lin Hu; Yizhou Li; You-Kai Xu; Bin Lin; Chuan-Rui Zhang
Source:: Journal of agricultural and food chemistry 2020 v.68 no.33 pp. 8825-8835
ISSN:: 1520-5118
Subject:: Cinnamomum; antioxidant activity; antioxidants; cell proliferation; circular dichroism spectroscopy; food chemistry; functional foods; lignans; neoplasm cells; spectral analysis
Abstract:: ... In the aim to evaluate the functional food property of Cinnamomum bejolghota, seven new lignans and neolignans, bejolghotins A–G (1–4 and 9–11), along with 14 known ones (5–8 and 12–21), were isolated and their structures including absolute configurations were elucidated by extensive spectroscopic data and electronic circular dichroism (ECD) analyses. All of the isolates were tested for antioxidan ...
DOI:: 10.1021/acs.jafc.0c02885
: https://doi.org/10.1021/acs.jafc.0c02885

74. Lignans from Euphorbia hirta L.

Author:: Ling Zhang; Xiao-Ling Wang; Bin Wang; Long-Teng Zhang; Hui-Min Gao; Tao Shen; Hong-Xiang Lou; Dong-Mei Ren; Xiao-Ning Wang
Source:: Natural product research 2021 v.36 no.1 pp. 26-36
ISSN:: 1478-6427
Subject:: Euphorbia hirta; lignans; medicinal plants; neoplasm cells; research; spectral analysis
Abstract:: ... Five new lignans, euphorhirtins A–D (1–4), 5-methoxyvirgatusin (5), three artefacts, 7S-ethoxyisolintetralin (6), 7R-ethoxyisolintetralin (7), and 7R-ethoxy-3-methoxyisolintetralin (8), together with 13 known ones (9–21) were isolated from the medicinal plant Euphorbia hirta L. The structures of the compounds were elucidated by means of extensive spectroscopic analysis, including 1D and 2D NMR and ...
DOI:: 10.1080/14786419.2020.1761358
: https://doi.org/10.1080/14786419.2020.1761358

75. Neolignans and Norlignans from Insect Medicine Polyphaga plancyi and Their Biological Activities

Author:: Hong-Jie Zhu; Te Xu; Yong-Ming Yan; Zheng-Chao Tu; Yong-Xian Cheng
Source:: Natural products and bioprospecting 2021 v.11 no.1 pp. 51-62
ISSN:: 2192-2195
Subject:: coagulation; extracellular matrix; humans; insects; lignans; medicine; norlignans; rats; spectral analysis
Abstract:: ... Ten neolignans or norlignans (1–10) including eight new compounds were isolated from the whole bodies of Polyphaga plancyi Bolivar. Their structures were identified by spectroscopic data. Compounds 3, 4, 8, and 9 are racemates indicated by chiral HPLC analysis. Chiral separation followed by ECD calculations allowed to clarify the absolute configurations of all the antipodes. All the new compounds ...
DOI:: 10.1007/s13659-020-00262-0
: https://doi.org/10.1007/s13659-020-00262-0

76. New Terpenoids And Lignans From The Twigs Of Tripterygium Hypoglaucum

Author:: Hui Zheng; Li Wang; Tao Yang; Dan Liu; Hong-Mei Li; Xuan-Qin Chen; Rong-Tao Li
Source:: Natural product research 2020 v.34 no.13 pp. 1853-1861
ISSN:: 1478-6427
Subject:: Tripterygium; branches; cytotoxicity; ethanol; inhibitory concentration 50; lignans; spectral analysis; terpenoids
Abstract:: ... Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9′-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cells, with an IC₅₀ value of 30.1 μM in vitro. ...
DOI:: 10.1080/14786419.2018.1564297
: https://doi.org/10.1080/14786419.2018.1564297

77. Phenolic and Acid Derivatives from Artemisia sieversiana

Author:: Xiang-Wei Xu; Chao-Xi Chen; Ze-Dong Nan; Wen-Bing Sheng; Li-Min Gong; Xu-Dong Zhou
Source:: Chemistry of natural compounds 2021 v.57 no.2 pp. 250-253
ISSN:: 0009-3130
Subject:: Artemisia sieversiana; chemistry; circular dichroism spectroscopy; lignans; spectral analysis
Abstract:: ... A new lignan, named sieverlignan C (1), as well as nine known compounds (2–10), were isolated from the leaves and stems of Artemisia sieversiana. The structure of the new lignan was elucidated from detailed spectroscopic analysis, including HR-MS, NMR, and circular dichroism experiments. All the compounds were isolated from the A. sieversiana plant for the first time. ...
DOI:: 10.1007/s10600-021-03329-7
: https://doi.org/10.1007/s10600-021-03329-7

78. Pleiocarpumlignan A, a new dineolignan from Piper pleiocarpum Chang ex Tseng

Author:: Wen-Hui Xu; Xiao-Min Su; Xin-Min Zhang; JianHua Qi; Dawei Wang; Meng Wang; Qian Liang
Source:: Natural product research 2020 v.34 no.19 pp. 2809-2815
ISSN:: 1478-6427
Subject:: Piper; cell lines; chemical composition; cytotoxicity; humans; lignans; literature; neoplasm cells; research; spectral analysis
Abstract:: ... The investigation of chemical constituents from the whole plants Piper pleiocarpum Chang ex Tseng resulted in the isolation of one new dineolignan, pleiocarpumlignan A (1), along with one known benzoate derivative, trans-2,3-diacetoxy-1-[(benzoy1oxy)methyl]-cyclohexa-4,6-diene (2), and two known neolignans (3–4) as (±)-trans-dehydrodiisoeugenol (3), (7R,8R,3′S)-△⁸′-3′,6′-dihydro-3′-methoxy-3,4-met ...
DOI:: 10.1080/14786419.2019.1593167
: https://doi.org/10.1080/14786419.2019.1593167

79. Stable Axially Chiral Isomers of Arylnaphthalene Lignan Glycosides with Antiviral Potential Discovered from Justicia procumbens

Author:: Yang Zhao; Chuen-Fai Ku; Xin-Ya Xu; Nga-Yi Tsang; Yu Zhu; Chen-Liang Zhao; Kang-Lun Liu; Chuang-Chuang Li; Lijun Rong; Hong-Jie Zhang
Source:: Journal of organic chemistry 2021 v.86 no.8 pp. 5568-5583
ISSN:: 1520-6904
Subject:: Justicia procumbens; X-radiation; ambient temperature; antiviral agents; antiviral properties; biphenyl; circular dichroism spectroscopy; drug development; geometry; glycosides; lignans; methanol; optical isomerism; organic chemistry; phytochemicals; spectral analysis
Abstract:: ... Arylnaphthalene lignans (ANLs) were known to have axial chirality due to the biphenyl skeleton with hindered rotation at the single bond. However, the stable ANL atropisomers have not been isolated from nature until the present study. Phytochemical separation of the methanol extract of the stems and barks of Justicia procumbens led to the isolation of 11 ANL glycosides including four pairs of new ...
DOI:: 10.1021/acs.joc.1c00068
: https://doi.org/10.1021/acs.joc.1c00068

80. Structural elucidation, bio-inspired synthesis, and biological activities of cyclic diarylpropanes from Horsfieldia kingii

Author:: Rui Zhan; Dashan Li; Yuan-Lie Liu; Xiao-Yan Xie; Lei Chen; Li-Dong Shao; Wen-Jing Wang; Ye-Gao Chen
Source:: Tetrahedron 2020 v.76 no.40 pp. 131494
ISSN:: 0040-4020
Subject:: X-ray diffraction; acetone; bioactive properties; bioassays; biomimetic synthesis; branches; chemical reactions; chemical structure; circular dichroism spectroscopy; crystallography; enzyme inhibition; inducible nitric oxide synthase; inhibitory concentration 50; leaves; lignans; nitric oxide; phytochemicals; spectral analysis
Abstract:: ... Bioactivity-guided phytochemical investigation on 70% aqueous acetone extracts of the twigs and leaves of Horsfieldia kingii led to the isolation of two novel cyclic diarylpropanes (1 and 2) bearing a 2,3-dihydro-1H-indene core, one new diarylpropane (3), six known diarylpropanes (4–9), one flavanol (10), and seven lignans (11–17). Their structures were determined by extensive spectroscopic analys ...
DOI:: 10.1016/j.tet.2020.131494
: https://doi.org/10.1016/j.tet.2020.131494

81. Two neolignans from Penthorum Chinense and their antiproliferative activities

Author:: Doudou Huang; Zhiying Dong; Lei Sun; Wansheng Chen; Lianna Sun
Source:: Natural product research 2020 v.34 no.11 pp. 1515-1520
ISSN:: 1478-6427
Subject:: Penthorum chinense; circular dichroism spectroscopy; inhibitory concentration 50; lignans; spectral analysis
Abstract:: ... Chemical investigation of Penthorum chinense resulted in the isolation of two neolignans (1 and 2) together with two known compounds (3 and 4). The structures of compounds 1 and 2 were determined by interpretation of spectroscopic data, and absolute configurations were made based on electronic circular dichroism (ECD). All compounds were evaluated for their antiproliferative activity on hepatic st ...
DOI:: 10.1080/14786419.2018.1517261
: https://doi.org/10.1080/14786419.2018.1517261

82. Two new bioactive lignans from leaves and twigs of Cleistanthus concinnus Croizat

Author:: Shi-rui Fan; Jing-jing Guo; Yi-ting Wang; Bi-juan Yang; Duo-zhi Chen; Xiao-jiang Hao
Source:: Natural product research 2020 v.34 no.23 pp. 3328-3334
ISSN:: 1478-6427
Subject:: Cleistanthus; branches; cells; leaves; lignans; lipopolysaccharides; literature; research; spectral analysis
Abstract:: ... Two new lignans (1–2), along with five known compounds (3-7) with different structures were isolated from leaves and twigs of Cleistanthus concinnus Croizat. The new lignans were elucidated as (7′R,8′S)-3,3′,5′-trimethoxy-4,4′-dihydroxy-7-en-7′,9- epoxy-8,8′-lignan (1) and (7′R,8′S)-3,3′-dimethoxy-4,4′-dihydroxy-7-en-7′,9-epoxy-8, 8′-lignan (2) by comprehensive spectroscopic analysis including 1D ...
DOI:: 10.1080/14786419.2019.1569663
: https://doi.org/10.1080/14786419.2019.1569663

83. Two new furofuran lignan glycoside derivatives from the fruit of Forsythia suspensa

Author:: Qian Wei; Qin Wang; Chen-Zhi Sun; Tian-Yi Yu; Xin-Jia Yan; Jun Li; Jie Wei; Chang Li; Yue-Hu Pei
Source:: Journal of Asian natural products research 2020 v.22 no.9 pp. 803-809
ISSN:: 1477-2213
Subject:: Forsythia suspensa; cytotoxicity; ethanol; fruits; glycosides; human cell lines; inhibitory concentration 50; lignans; neoplasm cells; phytochemicals; spectral analysis
Abstract:: ... Phytochemical investigation of 95% ethanol extract of the fruit of Forsythia suspensa resulted in the isolation of two new furofuran lignan glycoside derivatives pinoresinoside A (1) and phillyrigeninside A (2), along with three known ones. Their structures were established based on extensive spectroscopic data analyses and comparison with literature data. Absolute configuration of 1 was determine ...
DOI:: 10.1080/10286020.2019.1666823
: https://doi.org/10.1080/10286020.2019.1666823

84. Two new lignans from Anemone vitifolia Buch.-Ham. and their anti-inflammatory activity

Author:: Lin-Yun Mou; Hai-Yan Wu; Li-Jiao Hu; Min Wei; Jian-Long Li; Gan-Peng Li
Source:: Phytochemistry letters 2020 v.38 pp. 133-135
ISSN:: 1874-3900
Subject:: anti-inflammatory activity; data analysis; in vitro studies; lignans; lipopolysaccharides; macrophages; mice; nitric oxide; plant biochemistry; spectral analysis
Abstract:: ... Two new lignans (1–2), together with two known lignans (3–4), were isolated from the whole herb of Anemone vitifolia. The structures were identified based on extensive spectroscopic data analysis and comparison with reported data. All compounds of this plant were reported for the first time. In vitro test, all compounds were evaluated for their anti-inflammatory activity via calculating the produc ...
DOI:: 10.1016/j.phytol.2020.06.001
: https://doi.org/10.1016/j.phytol.2020.06.001

85. Two new lignans from Gymnotheca involucrata

Author:: Shi-Ji Xiao; Mao-Sheng Zhang; Fang Chen; Li-Sheng Ding; Yan Zhou
Source:: Natural product research 2020 v.34 no.3 pp. 329-334
ISSN:: 1478-6427
Subject:: Gram-negative bacteria; Gram-positive bacteria; Gymnotheca involucrata; antimicrobial properties; bioassays; lignans; spectral analysis
Abstract:: ... A new dibenzocyclooctdiene (1), and a new eupodienone (2) type lignans were isolated along with five known analogues from the whole plant of Gymnotheca involucrata Pei. The structures of the new compounds were elucidated on the basis of detailed spectroscopic analysis. Bioassay results showed that compounds 1 and 2 exhibited no antimicrobial activity against four Gram-positive bacterial strains an ...
DOI:: 10.1080/14786419.2018.1530997
: https://doi.org/10.1080/14786419.2018.1530997

86. A new abietane diterpene and anti-complementary constituents from Juniperus tibetica

Author:: Dong-Lin Zeng; Chang-Yue Wang; Hui-Qin Gao; Dao-Feng Chen; Yan Lu
Source:: Natural product research 2021 v.35 no.20 pp. 3452-3459
ISSN:: 1478-6427
Subject:: Juniperus; X-ray diffraction; coumarin; diterpenoids; flavones; fractionation; lignans; research; spectral analysis
Abstract:: ... Anti-complementary activity-guided fractionation led to the isolation of a new abietane diterpene (1) and twenty-five known compounds (2–26) from the twigs and leaves of Juniperus tibetica. All the compounds were isolated from J. tibetica for the first time. The structure of 1 was assigned by spectroscopic data and X-ray crystallography analysis. Five lignans (2, 3, 7, 9 and 10), two flavones (19 ...
DOI:: 10.1080/14786419.2019.1709191
: https://doi.org/10.1080/14786419.2019.1709191

87. A new aryltetralin lignan and other phytoconstituents from Atractylis humilis

Author:: Siham Sifouane; Imane Benabdelaziz; Mohammed Benkhaled; Santiago Gómez-Ruiz; Sandra Carralero; Hamada Haba
Source:: Biochemical systematics and ecology 2020 v.90 pp. 104018
ISSN:: 0305-1978
Subject:: Asteraceae; butanol; chemical constituents of plants; chemotaxonomy; ethyl acetate; lignans; nuclear magnetic resonance spectroscopy; phytochemicals; secondary metabolites; spectral analysis
Abstract:: ... Phytochemical research of the whole plant Atractylis humilis (Asteraceae family) led to the isolation of one cyclolignan, namely (8R,7′S,8′S)-9′-β-D-glucopyranosyl-3,4′,9-trihydroxy-3′,4,5,5′-tetramethoxy-2,7′-cyclolignan (1), together with thirteen known phytochemicals 2–14 from the ethyl acetate and n-butanol extracts. The structures of all isolated secondary metabolites 1–14 were elucidated by ...
DOI:: 10.1016/j.bse.2020.104018
: https://doi.org/10.1016/j.bse.2020.104018

88. A new lignan from the flowers of Hibiscus sabdariffa L. (Malvaceae)

Author:: Truong Van Nguyen Thien; Lien Thi My Do; Phu Hoang Dang; Ngoc Vinh Huynh; Huu Phuc Dang; Thanh Tien Nguyen; Kim Thuy Tran; Duc Minh Nguyen Huu; Quang Ton That
Source:: Natural product research 2021 v.35 no.13 pp. 2218-2223
ISSN:: 1478-6427
Subject:: Hibiscus sabdariffa; antioxidants; lignans; research; spectral analysis
Abstract:: ... From MeOH-soluble fraction of the flowers of Hibiscus sabdariffa (Malvaceae), one new lignan, (+)-4-O-methyl-5′-methoxy-secoisolariciresinol (1), together with four known compounds (2–5) were isolated. The structures were elucidated based on NMR spectroscopic analysis. The absolute configuration of 1 was determined based on the Cotton effects in the CD spectrum. Compounds 1, 3 and 4 showed antioxi ...
DOI:: 10.1080/14786419.2019.1667354
: https://doi.org/10.1080/14786419.2019.1667354

89. A new lignan glycoside from Astragalus yunnanensis

Author:: Ming-Zao Zhao; Yi Shen; Wei Xu; Ying-Zhi Chen; Chao-Jiang Xiao; Bei Jiang
Source:: Journal of Asian natural products research 2020 v.22 no.6 pp. 594-600
ISSN:: 1477-2213
Subject:: Actinomyces viscosus; Astragalus; Candida albicans; Escherichia coli; Proteus vulgaris; Pseudomonas aeruginosa; Salmonella Typhi; Shigella dysenteriae; Staphylococcus aureus; Streptococcus mutans; antibacterial properties; antifungal properties; chemical structure; glycosides; lignans; methanol; nuclear magnetic resonance spectroscopy; plant extracts; roots; spectral analysis
Abstract:: ... A new lignan glycoside, astrayunoside A (1), along with eight known compounds (2–9), were obtained from the methanol extract of roots of Astragalus yunnanensis. All the compounds were obtained from A. yunnanensis for the first time. Their structures were elucidated by extensive spectroscopic analysis (1D and 2D-NMR, MS, UV, CD, and IR). The weak antibacterial activities of the crude extracts of A. ...
DOI:: 10.1080/10286020.2019.1607840
: https://doi.org/10.1080/10286020.2019.1607840

90. The Antioxidant Compounds from Urtica fissa Flowers

Author:: Mengyue Wang; Lili Wu; Hao Zhang; Dun Zhu Ci Ren; Tonghua Liu; Xiaobo Li
Source:: Chemistry of natural compounds 2019 v.55 no.5 pp. 839-842
ISSN:: 0009-3130
Subject:: 2,2-diphenyl-1-picrylhydrazyl; Urtica; antioxidants; chemical structure; flavonoids; flowers; lignans; median effective concentration; phenolic acids; spectral analysis
Abstract:: ... Eleven compounds (1–11), including two new compounds (1, 2), were isolated from the antioxidant portion of the alcoholic extract of Urtica fissa flowers. Their chemical structures were elucidated from extensive spectroscopic analysis. The results of activity evaluation indicated that some compounds of phenolic acids (3, 4), flavonoids (7, 9, 10), and lignans (1, 6) possess significant activities o ...
DOI:: 10.1007/s10600-019-02827-z
: https://doi.org/10.1007/s10600-019-02827-z

91. Bioassay-guided isolation of potential bioactive constituents from pomegranate agrifood by-product

Author:: Jilan A. Nazeam; Walaa A. AL-Shareef; Maged W. Helmy; Alaadin E. El-Haddad
Source:: Food chemistry 2020 v.326 pp. 126993
ISSN:: 0308-8146
Subject:: antimicrobial properties; bioactive compounds; byproducts; chromatography; cytotoxicity; food industry; functional foods; glycosides; hulls; lignans; pericarp; phenolic acids; pomegranates; quercetin; spectral analysis
Abstract:: ... Food industries are yielding annually plentiful by-products worldwide, these concomitants could be an excellent source of natural functional ingredients. Hence, the antimicrobial and cytotoxic effects of pomegranate husk were examined and chromatographic analyzes were applied for isolation of the bioactive compounds. Lignans; isohydroxymatairesinol, punicatannin C, flavonoids; phloretin, quercetin ...
DOI:: 10.1016/j.foodchem.2020.126993
: https://doi.org/10.1016/j.foodchem.2020.126993

92. Chemical Constituents of the Leaves of Campanula takesimana (Korean Bellflower) and Their Inhibitory Effects on LPS-induced PGE2 Production

Author:: Yutong Qi; Se-In Choi; So-Ri Son; Hee-Soo Han; Hye Shin Ahn; Yu-Kyong Shin; Sun Hee Lee; Kyung-Tae Lee; Hak Cheol Kwon; Dae Sik Jang
Source:: Plants 2020 v.9 no.9 pp. -
ISSN:: 2223-7747
Subject:: Campanula takesimana; Oriental traditional medicine; anti-inflammatory activity; chemical composition; chromatography; ferulic acid; glucosides; herbal medicines; herbs; kaempferol; leaves; lignans; lipopolysaccharides; nuclear magnetic resonance spectroscopy; prostaglandins; quercetin; spectral analysis; Korean Peninsula
Abstract:: ... Campanula takesimana Nakai (Campanulaceae; Korean bellflower) is one of the endemic herbs of Korea. The plant has been used as traditional medicines for treating asthma, tonsillitis, and sore throat in Korea. A hot water extract of the leaves of C. takesimana exhibited a significant inhibitory effect on lipopolysaccharide (LPS)-stimulated prostaglandin E₂ (PGE₂) production. Repetitive chromatograp ...
DOI:: 10.3390/plants9091232
: https://doi.org/10.3390/plants9091232

93. Chemical constituents from the fruits of Melia azedarach (Meliaceae)

Author:: Wenqi Wang; Zhenzhen Xia; Zhenhua Tian; Haiqiang Jiang; Yanfei Zhan; Changxin Liu; Chuanhou Li; Honglei Zhou
Source:: Biochemical systematics and ecology 2020 v.92 pp. 104094
ISSN:: 0305-1978
Subject:: Melia azedarach; carbon; chemical composition; chemotaxonomy; fruits; lignans; nuclear magnetic resonance spectroscopy; spectral analysis; stable isotopes; triterpenoids
Abstract:: ... A new apotirucallane-type triterpenoid, 3α-benzoate triterpenoid A (1), along with six known triterpenoids (2–7), one aromatic ester (8) and eight lignans (9–16), were isolated from the fruits of Melia azedarach Linn. The structure of 1 was determined by spectral analyses, including HR-ESI-MS, 1D NMR (¹H NMR and ¹³C NMR) and 2D NMR (HSQC and HMBC) analyses. 10, 11 and 16 were reported for the firs ...
DOI:: 10.1016/j.bse.2020.104094
: https://doi.org/10.1016/j.bse.2020.104094

94. Chemical constituents from the fruits of Phyllanthus emblica L.

Author:: Fan Yang; Aftab Yaseen; Bin Chen; Fu Li; Lun Wang; Weicheng Hu; Mingkui Wang
Source:: Biochemical systematics and ecology 2020 v.92 pp. 104122
ISSN:: 0305-1978
Subject:: Euphorbiaceae; Phyllanthus emblica; chemical composition; chemotaxonomy; fruits; lignans; polyphenols; spectral analysis
Abstract:: ... Chemical investigation of the fruits of Phyllanthus emblica led to the isolation of one new aryltetralin-type lignan (1), along with twelve known polyphenols (2–13). Their structures were determined via extensive analyses of spectroscopic data and comparison with the reported literature values. Among them, polyphenols 1, 6, 7, and 10 were isolated from the family Euphorbiaceae for the first time. ...
DOI:: 10.1016/j.bse.2020.104122
: https://doi.org/10.1016/j.bse.2020.104122

95. Chemical constituents from the leaves of Crataegus pinnatifida Bge

Author:: Wanchun Chu; Pinyi Gao; Lingzhi Li
Source:: Biochemical systematics and ecology 2019 v.86 pp. 103923
ISSN:: 0305-1978
Subject:: Crataegus pinnatifida; carbon; chemical composition; chemical structure; chemotaxonomy; coumaric acids; flavonoids; leaves; lignans; nuclear magnetic resonance spectroscopy; spectral analysis; stable isotopes; triterpenoids
Abstract:: ... The phytochemical investigations on the leaves of Crataegus pinnatifida led to the isolation of 20 compounds, including seven triterpenoids (1-7), three hydroxycinnamic acids (8-10), three lignans (11-13) and seven flavonoids (14-20). All chemical structures were established on the basis of NMR (1H NMR, 13C NMR) spectroscopic data. Meanwhile, compounds 3-12 are reported for the ﬁrst time from Crat ...
DOI:: 10.1016/j.bse.2019.103923
: https://doi.org/10.1016/j.bse.2019.103923

96. Chemical constituents from the rhizome of Anemone hupehensis

Author:: Xia-Yin Wang; Yang Liu; Hui Li; Wei Zhang; Hai-Feng Tang; Yun-Yang Lu
Source:: Biochemical systematics and ecology 2020 v.93 pp. 104145
ISSN:: 0305-1978
Subject:: Anemone hupehensis; chemical composition; chemotaxonomy; lignans; phytochemicals; rhizomes; spectral analysis; triterpenoid saponins
Abstract:: ... A phytochemical investigation on the rhizome of Anemone hupehensis resulted in the isolation of thirteen compounds, including six neolignan glycosides (1-6), two phenylpropanoid glycosides (7, 8), a phenolic glycoside (9) and four triterpenoid saponins (10-13). The structures of the isolated compounds were elucidated on the basis of spectroscopic data. This is the first report of neolignan glycosi ...
DOI:: 10.1016/j.bse.2020.104145
: https://doi.org/10.1016/j.bse.2020.104145

97. Chemical constituents isolated from Valeriana officinalis L

Author:: Hao Fan; Yuze Li; Xiaofei Liang; Shuting Yan; Yuwen Cui; Huawei Zhang; Wenli Huang; Xinjie Yang; Xiaomei Song
Source:: Biochemical systematics and ecology 2020 v.93 pp. 104143
ISSN:: 0305-1978
Subject:: Valeriana officinalis; aldehydes; chemical composition; chemotaxonomy; iridoids; leaves; lignans; nuclear magnetic resonance spectroscopy; phytochemicals; sesquiterpenoids; spectral analysis
Abstract:: ... Phytochemical investigations on the leaves of Valeriana officinalis L. led to the isolation of 18 compounds, including eight lignans (1–8), three sesquiterpenoids (9–11), five iridoids (12–16), and two aldehydes (17–18) The structure elucidation of isolated compounds was achieved on the basis of NMR and mass spectral data. Among them, three compounds (9–16, 18) are reported from V. officinalis for ...
DOI:: 10.1016/j.bse.2020.104143
: https://doi.org/10.1016/j.bse.2020.104143

98. Chemical constituents isolated from the roots of Sanguisorba officinalis L. and their chemotaxonomic significance

Author:: Rongshen Wang; Jinfeng Sun; Chao Ye; Jiaming Wang; Tieqiang Zong; Wei Zhou; Gao Li
Source:: Biochemical systematics and ecology 2020 v.89 pp. 103999
ISSN:: 0305-1978
Subject:: Sanguisorba officinalis; chemical composition; chemical structure; chemotaxonomy; flavonoids; glycosides; lignans; monoterpenoids; phenols; roots; spectral analysis; triterpenoids
Abstract:: ... Phytochemical investigation of the roots of Sanguisorba officinalis L. led to the isolation of thirty-eight compounds, including seventeen triterpenoids (1–17), six monoterpenoid glycosides (18–23), six flavonoids (24–29), six phenols (30–35), two glycosides (36–37), and one lignan (38). The chemical structures of these compounds were elucidated on the basis of spectral data and by comparisons of ...
DOI:: 10.1016/j.bse.2019.103999
: https://doi.org/10.1016/j.bse.2019.103999

99. Furofuran lignans and alkaloids from Clinacanthus nutans

Author:: Hong-Zhang Diao; Wen-Hao Chen; Jian Cao; Tai-Ming Shao; Xiao-Ping Song; Chang-Ri Han
Source:: Natural product research 2019 v.33 no.9 pp. 1317-1321
ISSN:: 1478-6427
Subject:: Clinacanthus nutans; aerial parts; alkaloids; ethanol; human cell lines; humans; inhibitory concentration 50; lignans; neoplasm cells; spectral analysis
Abstract:: ... One new furofuran lignan 2-methoxy-9β-hydroxydiasesamin (1), and four analogues (2–5), together with eight alkaloids (6–13), were isolated from the ethanol extract of the aerial part of Clinacanthus nutans. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All the compounds were isolated from the genus of Clinacanthus for the first time. In addition, li ...
DOI:: 10.1080/14786419.2018.1475375
: https://doi.org/10.1080/14786419.2018.1475375

100. Furofuranone Lignans from Leucophyllum ambiguum

Author:: María Y. Rios; Yordin D. Ocampo-Acuña; M. Ángeles Ramírez-Cisneros; María E. Salazar-Rios
Source:: Journal of natural products 2020 v.83 no.5 pp. 1424-1431
ISSN:: 1520-6025
Subject:: Alzheimer disease; Leucophyllum; X-ray diffraction; acetylcholinesterase; aerial parts; air drying; amino acids; beta-sitosterol; carbon; conformational isomerization; crystallography; derivatization; etiology; grants; lignans; moieties; nuclear magnetic resonance spectroscopy; oxygen; spectral analysis; stable isotopes; veratric acid
Abstract:: ... Eight furofuranone lignans with an endo,endo relationship between the oxygen atoms, an exo,exo relationship between the aryl groups, and a chair,chair conformation (1–4 and 6–9), in addition to the α-amino acid (3S)-hydroxy-3′,4′-dimethoxy-L-phenylalanine (5), veratric acid (10), and β-sitosterol (11), were isolated from the powdered and defatted air-dried aerial parts of Leucophyllum ambiguum. Fo ...
DOI:: 10.1021/acs.jnatprod.9b00759
: https://doi.org/10.1021/acs.jnatprod.9b00759

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1. Anti-hypoxic active constituents from the twigs of Zanthoxylum armatum DC. and their chemotaxonomic significance

2. Antiviral and Antioxidant Components from the Fruits of Illicium verum Hook.f. (Chinese Star Anise)

3. Bioactive neolignans and lignans from the roots of Paeonia lactiflora

4. Bis-iridoids and other constituents from Scabiosa semipapposa

5. Chemical and biological studies of Daphniphyllum oldhamii from Hunan Province, China

6. Chemical constituents from Dracocephalum moldavica L. and their chemotaxonomic significance

7. Chemical constituents from Maytenus hookeri

8. Chemical constituents from Salvinia natans (L.) All. (Salviniaceae) and their chemotaxonomic significance

9. Chemical constituents from the aerial parts of Achillea alpina and their chemotaxonomic significance

10. Chemical constituents from the fruits of Illicium simonsii and their antiviral activity and neuroprotective effect

11. Chemical constituents from the leaves of Caesalpinia bonduc (L.) Roxb. and their chemotaxonomic significance

12. Chemical constituents from the roots of Actinidia valvata Dunn

13. Ionones and lignans from the fresh roots of Rehmannia glutinosa

14. Isolation and Characterization of Anti-Inflammatory Lignans from Oenanthe javanica

15. Lignans and sesquiterpenoids from the stems of Schisandra bicolor var. tuberculata

16. Lignans and terpenoids from Gaultheria leucocarpa var. yunnanensis and their anti-inflammatory and antioxidant activities

17. A New Geranylated Lignan from Oenanthe javanica and Anti-Inflammatory Activity

18. New lignans and diterpenoid glycosides from the fruits of Xanthium italicum Moretti

19. Procyanidins and Phlobatannins from the Twigs of Rosa multiflora and Their Neuroprotective Activity

20. Thujasutchins N and O, two new compounds from the stems and roots of Thuja sutchuenensis

21. A new lignan from the stems of Buchanania lucida Blume (Anacardiaceae)

22. Amino ether analogues of 4,4′-dihydroxy-3-methoxy-6,7′-cyclolignan and their activity against drug-resistant bacteria

23. Aromatic Cadinane Sesquiterpenoids from the Fruiting Bodies of Phellinus pini Block SARS-CoV-2 Spike–ACE2 Interaction

24. Bassiamide A, a new alkaloid from xero-halophyte Bassia indica Wight.

25. Characteristic constituents with chemotaxonomic significance from the gum resin of Boswelliacarterii

26. Chemical constituents and aldose reductase inhibitory activities of Betula alba bark and leaves

27. Chemical constituents from Melodinus cochinchinensis (Lour.) Merr. and their chemotaxonomic significance

28. Chemical constituents from Semiliquidambar chingii and their chemotaxonomic significance

29. Chemical constituents from the fruits of Vitex rotundifolia and their chemotaxonomic significance

30. Chemical constituents from the roots of Cichorium glandulosum Boiss. et Huet (Asteraceae)

31. Chemical constituents of the pericarp of Toona sinensis and their chemotaxonomic significance

32. Chevalierinol A and B, two new neolignan sesquiterpenoids from Magnolia chevalieri

33. Dibenzocyclooctadiene lignans from Artemisia sieversiana and their anti-inflammatory activities

34. Dibenzocyclooctadiene lignans from the root bark of Schisandra sphenanthera

35. Enantiomeric lignans with antineuroinflammatory activities from Mappianthus iodoides

36. Guaiane-rich phytochemical profile of Centaurea kotschyi subsp. persica (Boiss.) Wagenitz and identification of hypoglycaemic metabolites

37. Lignans and monoterpenes from Daphne penicillata Rehd and their chemotaxonomic significance

38. Lignans with NO inhibitory activity from Tinospora sinensis

39. Neolignan and phenylpropanoid compounds from the resin of Styrax tonkinensis

40. Neolignans and Diarylheptanoids with Anti-Inflammatory Activity from the Rhizomes of Alpinia zerumbet

41. Neolignans and amide alkaloids from the stems of Piper kadsura and their neuroprotective activity

42. Neolignans from Piper betle Have Synergistic Activity against Antibiotic-Resistant Staphylococcus aureus

43. A New Lignan from the Leaves of Orthosiphon aristatus

44. New phenylpropanoids from the fruits of Xanthium sibiricum and their anti-inflammatory activity

45. Phenolic compounds and triterpenes from the roots of Vaccinium dunalianum Wight and their chemotaxonomic significance

46. Phenylpropanoid conjugated iridoids with anti-malarial activity from the leaves of Morinda morindoides

47. Phytochemical and chemotaxonomic studies on Phyllodium pulchellum (Leguminosae)

48. Potential inhibitors of microglial activation from the roots of Vernicia montana Lour

49. Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities

50. Two New Lignans from the Fresh Bark of Ailanthus altissima

51. Two new ditetrahydrofuran lignans from Artemisia sieversiana

52. Tyrosinase Inhibitors Derived from Chemical Constituents of Dianella ensifolia

53. A new 7′,9-epoxylignan from the stems of Salacia chinensis

54. Amides and lignans from Solanum lyratum

55. Anti-Inflamatory Activity of Neolignan Compound Isolated from the Roots of Saururus chinensis

56. Anti-β-amyloid aggregation activity of enantiomeric furolactone-type lignans from Archidendron clypearia (Jack) I.C.N.

57. Antiproliferative constituents from the aerial parts of Chrysophthalmum montanum (DC.) Boiss

58. Aromatic compounds from Endocomia macrocoma

59. Bioactive constituents of Lindernia crustacea and its anti-EBV effect via Rta expression inhibition in the viral lytic cycle

60. Bioactive tetrahydrofuran lignans from roots, stems, leaves and twigs of Anogeissus rivularis

61. Catechins and lignan from the flower buds of Rosa chinensis Jacq.

62. Chemical constituents from Ailanthus altissima (Mill.) Swingle and chemotaxonomic significance

63. Chemical constituents from Anemone vitifolia Buch.-Ham. (Ranunculaceae)

64. Chemical constituents from Hovenia dulcis Thunb. And their chemotaxonomic significance

65. Chemical constituents from Laggera pterodonta and their anti-inflammatory activities in vitro

66. Chemical constituents from Phlomis bovei Noë and their chemotaxonomic significance

67. Chemical constituents from the fruits of Solanum incanum L

68. Chemical constituents from the leaves of Lyonia ovalifolia var. hebecarpa

69. Cytotoxic lignans from fruits of Cleistanthus tonkinensis

70. Extractives elucidation of Taiwania cryptomerioides sapwood