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- Sun, Chunlong; Du, Wen; Wang, Baoqin; Yao, Zhigang; Liu, Junhua; Wang, Jun; Xie, Wenjun; Wu, Tao; Fan, Yanhui; Yang, Hongjun
- Biochemical and biophysical research communications 2017
- image analysis, etc ; 3-mercaptopropionic acid; acute toxicity; deoxyglucose; fluorescence; fluorescent dyes; glucose; glycolysis; membrane permeability; mice; neoplasm cells; neoplasms; photostability; tissues; toxicity testing; Show all 15 Subjects
- ... Malignant neoplasms exhibit an elevated rate of glycolysis and a high demand for glucose over normal cells. This characteristic can be exploited for in vivo imaging and tumor targeting examined. In this manuscript, we describe the synthesis of near-infrared (NIR) fluorochrome IR-822-labeled 2-amino-2-deoxy-d-glucose (DG) for optical imaging of tumors in mice. NIR fluorescent dye IR-820 was subsequ ...