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- Guthrie, Gregory; Tackett, Bryan; Stoll, Barbara; Martin, Camilia; Olutoye, Oluyinka; Burrin, Douglas G.
- Journal of Parenteral and Enteral Nutrition 2017 v.20 no.10 pp. 1-12
- piglets, etc ; ABC transporters; Kupffer cells; agonists; bacteria; bile acids; bile salts; endotoxins; enteral feeding; hepatocytes; in vitro studies; in vivo studies; inflammation; interleukins; lipopolysaccharides; liver; liver diseases; neonates; parenteral feeding; phytosterols; soybean oil; synergism; Show all 22 Subjects
- ... Introduction: Phytosterols are implicated in the development of parenteral nutrition–associated liver disease. A newly proposed mechanism for phytosterol-mediated parenteral nutrition–associated liver disease is through phytosterol-facilitated hepatic proinflammatory cytokine release following exposure to intestinally derived bacteria. Whether the proinflammatory effects are liver cell specific ...
- Wang, Lei; Qin, Wanhai; Ruidong, Zhai; Liu, Shiting; Zhang, Hu; Sun, Changjiang; Feng, Xin; Gu, Jingmin; Du, Chongtao; Han, Wenyu; Langford, P.R.; Lei, Liancheng
- Microbial pathogenesis 2015 v.78 pp. 74-86
- piglets, etc ; ABC transporters; Actinobacillus pleuropneumoniae; DNA microarrays; Western blotting; adhesins; amino acids; apoptosis; bacteria; caspase-3; confocal microscopy; disease control; energy metabolism; flow cytometry; gene expression regulation; genes; infectious diseases; lungs; macrophages; microarray technology; nucleotide sequences; pleuropneumonia; pork industry; reverse transcriptase polymerase chain reaction; scanning electron microscopy; serotypes; transcription (genetics); transmission electron microscopy; vaccine development; virulence; vitamin metabolism; Show all 31 Subjects
- ... Actinobacillus pleuropneumoniae (A. pleuropneumoniae) is the causative agent of porcine pleuropneumonia, a disease that causes serious problems for the swine industry. Successful infection by this bacterium requires breaking the first line of defence in the lungs, the primary alveolar macrophages (PAMs). Therefore, exploring A. pleuropneumoniae–PAM interactions will provide vital groundwork for th ...