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- Chi-I Chang; Chih-Ming Hsu; Ting-Syuan Li; Shen-Da Huang; Chen-Chen Lin; Chia-Hung Yen; Chang-Hung Chou; Hsueh-Ling Cheng
- Journal of functional foods 2014 v.10 pp. 260-273
- AMP-activated protein kinase; Cucurbita moschata; animal disease models; ferulic acid; glycemic effect; insulin; insulin resistance; insulin-like effect; mice; noninsulin-dependent diabetes mellitus; pumpkins; screening
- ... Pumpkin has been suggested to have an antidiabetic effect, but the bioactives involved and molecular mechanisms mediating its hypoglycaemic activity are not clear. This study characterized some of the hypoglycaemic constituents in the crude extract of the Cucurbita moschata stem and investigated the mechanisms of their action. The C. moschata stem extract showed a hypoglycaemic effect in vivo in s ...