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- Zhou, Quancheng; Feng, Chuanxing; Ruan, Zheng
- RSC advances 2017 v.7 no.13 pp. 7914-7919
- guinea pigs, etc ; AMP-activated protein kinase; analytical kits; biopsy; genistein; immunohistochemistry; malondialdehyde; melanin; models; pigmentation; prostaglandin synthase; rapamycin; secretion; staining; superoxide dismutase; ultraviolet radiation; Show all 16 Subjects
- ... In this study, to improve the properties of genistein, a genistein derivative (GD) was designed and synthesized by combining it with 1-benzylpiperazine. Then, the effects of GD on skin pigmentation in guinea pigs induced by ultraviolet B (UVB) radiation were studied. The guinea pigs were divided into a model group and a GD group. The GD group was coated with different doses of GD for 30 days. Biop ...