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1. White snakeroot poisoning in goats: Variations in toxicity with different plant chemotypes

Author:
Davis, T.Z.; Stegelmeier, B.L.; Lee, S.T.; Collett, M.G.; Green, B.T.; Pfister, J.A.; Evans, T.J.; Grum, D.S.; Buck, S.
Source:
Research in veterinary science 2016 v.106 pp. 29-36
ISSN:
0034-5288
Subject:
poisonous plants,   etc   ; Ageratina altissima; blood serum; chemotypes; exercise; goats; ketones; lesions (animal); muscles; poisoning; toxicity; toxins;     Show all 12 Subjects
Abstract:
... Tremetone and possibly other benzofuran ketones are believed to be the toxic compounds in white snakeroot. However, disease has not been reproduced with purified toxins and the concentrations of the benzofuran ketones in white snakeroot populations that cause toxicosis have not been documented. The objectives of this study were to compare the toxicity of seven plant populations, better characteriz ...
Handle:
10113/62915
DOI:
10.1016/j.rvsc.2016.02.008
Chorus Open Access:
10.1016/j.rvsc.2016.02.008

2. Toxicity of White Snakeroot (Ageratina altissima) and Chemical Extracts of White Snakeroot in Goats

Author:
Davis, T. Zane; Lee, Stephen T.; Collett, Mark G.; Stegelmeier, Bryan L.; Green, Benedict T.; Buck, Steven R.; Pfister, James A.
Source:
Journal of agricultural and food chemistry 2015 v.63 no.7 pp. 2092
ISSN:
0021-8561
Subject:
poisonous plants,   etc   ; Ageratina altissima; poisoning; humans; exercise; blood serum; enzyme activity; goats; hexane; ketones; milk; milk sickness; plant extracts; toxicity; tremetone;     Show all 15 Subjects
Abstract:
... White snakeroot (Ageratina altissima) is a sporadically toxic plant that causes trembles in livestock and milk sickness in humans that drink tainted milk. The putative toxin in white snakeroot is tremetone and possibly other benzofuran ketones, even though it has not been demonstrated in vivo. Toxic white snakeroot was dosed to goats, and they developed clinical signs of poisoning, exercise intole ...
Handle:
10113/62823
DOI:
10.1021/jf505614z
CHORUS:
10.1021/jf505614z