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You searched for: Subject term CD8-positive T-lymphocytes Remove constraint Subject term: CD8-positive T-lymphocytes Subject term permeability Remove constraint Subject term: permeability
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- Romy Razakandrainibe; Stéphane Pelleau; Georges E. Grau; Ronan Jambou
- Trends in parasitology 2012 v.28 no.4 pp. 151-160
- CD8-positive T-lymphocytes; antigen presentation; antigen-presenting cells; antigens; cerebral malaria; edema; endothelial cells; inflammation; parasites; parasitology; pathogens; pathophysiology; permeability
- ... Disruption of the endothelial cell (EC) barrier leads to pathology via edema and inflammation. During infections, pathogens are known to invade the EC barrier and modulate vascular permeability. However, ECs are semi-professional antigen-presenting cells, triggering T-cell costimulation and specific immune-cell activation. This in turn leads to the release of inflammatory mediators and the destruc ...
- Aline Corado Gomes; Allain Amador Bueno; Rávila Graziany Machado de Souza; João Felipe Mota
- Nutrition journal 2014 v.13 no.1 pp. 60
- CD8-positive T-lymphocytes; adhesion; animal models; autoimmunity; humans; immune response; inflammation; insulin receptors; insulin resistance; insulin-dependent diabetes mellitus; intestinal microorganisms; intestinal mucosa; laboratory animals; noninsulin-dependent diabetes mellitus; oxidative stress; permeability; phosphorylation; probiotics; prognosis; serine
- ... Diabetes is a condition of multifactorial origin, involving several molecular mechanisms related to the intestinal microbiota for its development. In type 2 diabetes, receptor activation and recognition by microorganisms from the intestinal lumen may trigger inflammatory responses, inducing the phosphorylation of serine residues in insulin receptor substrate-1, reducing insulin sensitivity. In typ ...
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3. CD8 T cell-derived perforin aggravates secondary spinal cord injury through destroying the blood-spinal cord barrier
- Zhaoxiang Liu; Hua Zhang; Hong Xia; Baocheng Wang; Renwen Zhang; Qun Zeng; Lingzhi Guo; Kui Shen; BaTa Wang; Yanheng Zhong; Zhizhong Li; Guodong Sun
- Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
- CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
- ... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...
4. Germinated black soybean fermented with Lactobacillus pentosus SC65 alleviates DNFB-induced delayed-type hypersensitivity in C57BL/6N mice
- Hye-Ji Lee; Ha-Eun Cho; Hye-Jin Park
- Journal of ethnopharmacology 2021 v.265 pp. 113236
- 2,2-diphenyl-1-picrylhydrazyl; CD8-positive T-lymphocytes; Lactobacillus pentosus; Oriental traditional medicine; Pediococcus pentosaceus; Rhynchosia; anti-inflammatory activity; antioxidant activity; chemokine CCL5; daidzein; delayed hypersensitivity; dexamethasone; diabetes; ears; ethanol; foods; genistein; glycitein; hyperplasia; hypertension; immunity; immunohistochemistry; inflammation; interleukin-10; interleukin-1beta; interleukin-6; lactic acid bacteria; lipopolysaccharides; macrophages; messenger RNA; mice; natural killer cells; osteoporosis; permeability; polyphenols; reverse transcriptase polymerase chain reaction; soybeans; tumor necrosis factors; East Asia
- ... Rhynchosia nulubilis (black soybean) has many applications in oriental medicine. It is traditionally used to treat disease related with high blood pressure, diabetes, inflammation, and osteoporosis. Furthermore, fermented soybean foods have traditionally been used for immunity enhancement in East Asia. However, the anti-inflammatory effects of germinated R. nulubilis (GR) against delayed-type hype ...