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- Choder, Mordechai, et al. Show all 6 Authors
- Cell 2011 v.147 no.7 pp. 1473-1483
- DNA; cytoplasm; messenger RNA; promoter regions; reporter genes; transactivators; yeasts
- ... Promoters are DNA elements that enable transcription and its regulation by trans-acting factors. Here, we demonstrate that yeast promoters can also regulate mRNA decay after the mRNA leaves the nucleus. A conventional yeast promoter consists of a core element and an upstream activating sequence (UAS). We find that changing UASs of a reporter gene without altering the transcript sequence affects th ...