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You searched for: Subject term Danio rerio Remove constraint Subject term: Danio rerio
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1. (Eco)toxicological effects of 2,4,7,9-tetramethyl-5-decyne-4,7-diol (TMDD) in zebrafish (Danio rerio) and permanent fish cell cultures

Author:
Krisztina Vincze; Martin Gehring; Thomas Braunbeck
Source:
Environmental science and pollution research international 2014 v.21 no.13 pp. 8233-8241
ISSN:
0944-1344
Subject:
Danio rerio; acute effects; bioaccumulation; biodegradation; carcinogenicity; cell culture; cytotoxicity; developmental stages; developmental toxicity; fish; genotoxicity; in vivo studies; industry; long term effects; mortality; paper; pesticides; physicochemical properties; reproduction; risk; rivers; screening; sexual development
Abstract:
... 2,4,7,9-tetramethyl-5-decyne-4,7-diol (TMDD) is a high-production volume chemical used in paper, ink, pesticide, and adhesive industries as a wetting and anti-foaming agent. The physicochemical properties and slow biodegradation rate of TMDD indicate a low bioaccumulation potential but a high prevalence in the environment. As a consequence, TMDD has been detected in several European rivers in the ...
DOI:
10.1007/s11356-014-2806-y
PubMed:
24687796

2. 0# Diesel water-accommodated fraction induced lipid homeostasis alteration in zebrafish embryos

Author:
Xiyan Mu; Jia Liu; Ke Yang; Ying Huang; Xuxing Li; Wenbo Yang; Suzhen Qi; Wenqing Tu; Gongming Shen; Yingren Li
Source:
Environmental pollution 2018 v.242 pp. 952-961
ISSN:
0269-7491
Subject:
Danio rerio; cholesterol; diacylglycerols; embryo (animal); fatty acids; freshwater; freshwater ecosystems; gene ontology; genes; homeostasis; lipid composition; lipid metabolism; mortality; petroleum; pharmacokinetics; physiological transport; pollution; quantitative polymerase chain reaction; risk; sequence analysis; surface water; transcription (genetics); triacylglycerols; China
Abstract:
... To investigate the developmental effects and corresponding molecular mechanism of diesel in freshwater organisms, zebrafish embryos were exposed to 0# diesel water-accommodated fraction (WAF) at different concentrations. Mortality, embryonic morphological endpoints, transcriptional profile and lipid profile were evaluated after exposure. Exposure to 0# diesel WAF had no significant effect on the s ...
DOI:
10.1016/j.envpol.2018.07.055

3. 073 Interactions between Zebrafish embryos and ice crystals during isothermal freezing and rapid cooling

Author:
Noel P. Abraham; Kathleen M. Bommer; Angela DiBenedetto; Jens O.M. Karlsson
Source:
Cryobiology 2013 v.67 no.3 pp. 418
ISSN:
0011-2240
Subject:
Danio rerio; additives; aquaculture; biomedical research; blastoderm; chorion; cooling; cryopreservation; crystallization; crystals; freezing; ice; image analysis; mammals; opacity; shrinkage; somatic cells; sowing; standard deviation; viability
Abstract:
... Cryopreservation of embryos from zebrafish (Danio rerio) and other teleosts would benefit biomedical research, commercial aquaculture, and ecological conservation, but is not yet feasible. Rapid changes in embryo opacity (e.g., darkening) observed almost immediately upon initial contact between zebrafish embryos and external ice crystals have previously been attributed to intracellular ice formati ...
DOI:
10.1016/j.cryobiol.2013.09.079

4. 1,2‐dibromo‐4‐(1,2 dibromoethyl) cyclohexane (TBECH)–mediated steroid hormone receptor activation and gene regulation in chicken LMH cells

Author:
Solomon Asnake; Ajay Pradhan; Joubert Banjop‐Kharlyngdoh; Carina Modig; Per‐Erik Olsson
Source:
Environmental toxicology and chemistry 2014 v.33 no.4 pp. 891-899
ISSN:
0730-7268
Subject:
DNA methylation; Danio rerio; apoptosis; bromination; chickens; flame retardants; gene activation; genes; household equipment; in vitro studies; polymerase chain reaction; receptors; steroid hormones; testosterone; wildlife
Abstract:
... The incorporation of brominated flame retardants into industrial and household appliances has increased their occurrence in the environment, resulting in deleterious effects on wildlife. With the increasing restraints on available compounds, there has been a shift to using brominated flame retardants that has seen the production of alternative brominated flame retardants such as 1,2‐dibromo‐4‐(1,2 ...
DOI:
10.1002/etc.2509
PubMed:
24375616

5. 1,3‐1‐6 ß‐glucans enhance tissue regeneration in zebrafish (Danio rerio): Potential advantages for aquaculture applications

Author:
Baldassare Fronte; Cheol‐Hee Kim; Marco Bagliacca; Lucia Casini; Mahanama De Zoysa
Source:
Aquaculture research 2019 v.50 no.11 pp. 3163-3170
ISSN:
1355-557X
Subject:
Danio rerio; amputation; animal models; aquaculture; beta-glucans; diet; fish; gills; macrophages; oral administration; secondary infection; stocking rate; tissue repair; tissues
Abstract:
... High aquacultural rearing density and handling of fish may frequently result in skin or gills wounds, thereby facilitating the onset of secondary infections. The capacity of the zebrafish to regenerate tissues, as well as fins and other organs, makes it an ideal animal model for studying the mechanisms of tissue regeneration. Since macrophages are involved in tissue regeneration, a diet including ...
DOI:
10.1111/are.14270

6. 123 Development of cryopreservation protocol for zebrafish ovarian fragments using controlled slow cooling

Author:
S. Anil; D.M. Rawson; T. Zhang
Source:
Cryobiology 2013 v.67 no.3 pp. 433
ISSN:
0011-2240
Subject:
Danio rerio; acetates; adenosine triphosphate; ambient temperature; aquaculture; cooling; cryopreservation; cryoprotectants; eggs; fish; fisheries management; fluorescein; freezing; germplasm; humans; methanol; nitrogen; oocytes; ovarian follicles; potassium chloride; propidium; sowing; spermatozoa; staining; storage time; straw; survival rate; viability
Abstract:
... Cryopreservation of gametes is an important method of conservation of germplasm and has wide range of applications in aquaculture and fisheries management. Cryopreservation is the most efficient method for long term storage of genetic materials. Though fish sperm cryopreservation has been a success, developing successful protocols for eggs and embryo cryopreservation still remain elusive. Several ...
DOI:
10.1016/j.cryobiol.2013.09.129

7. 125 Investigation of the effects of different cryopreservation parameters on the genome of zebrafish (Danio rerio) embryos

Author:
Raju Ahmed; Emma Spikings; Andrew Thompsett; Shaobo Zhao; Tiantian Zhang
Source:
Cryobiology 2013 v.67 no.3 pp. 433-434
ISSN:
0011-2240
Subject:
DNA damage; DNA fragmentation; DNA repair; Danio rerio; additives; apoptosis; base pair mismatch; cold treatment; cryopreservation; cryoprotectants; embryo (animal); eukaryotic cells; genes; methanol; models; proteins
Abstract:
... In recent years, a large number of studies implicated cryopreservation to increased occurrence of various forms of mutations, increased DNA fragmentation and the event of apoptosis. However, the evidence emerged from such studies is somewhat inconclusive; and the current study argued that analysing the DNA damage response (DDR) from the cryopreserved cells would help characterise the nature of the ...
DOI:
10.1016/j.cryobiol.2013.09.131

8. 14-Membered Macrocyclic Ring-Derived Toolbox: The Identification of Small Molecule Inhibitors of Angiogenesis and Early Embryo Development in Zebrafish Assay

Author:
Aeluri Madhu; Pramanik Chinmoy; Chetia Lakshindra; Mallurwar Naveen Kumar; Balasubramanian Sridhar; Chandrasekar Gayathri; Kitambi Satish Srinivas; Arya Prabhat
Source:
Organic letters 2013 v.15 no.3 pp. 436-439
ISSN:
1523-7052
Subject:
Danio rerio; angiogenesis; chemical reactions; chemical structure; embryogenesis; neurogenesis; organic compounds
Abstract:
... A highly practical and modular synthesis to obtain a diverse 14-membered ring-based macrocyclic toolbox is achieved. These compounds were further tested in zebrafish assays related to early embryonic development, angiogenesis, and neurogenesis, respectively. 1.4c was identified as an antiangiogenesis agent. ...
DOI:
10.1021/ol3032126

9. 16S rRNA amplicon sequencing dataset for conventionalized and conventionally raised zebrafish larvae

Author:
Daniel J. Davis; Elizabeth C. Bryda; Catherine H. Gillespie; Aaron C. Ericsson
Source:
Data in Brief 2016 v.8 pp. 938-943
ISSN:
2352-3409
Subject:
Danio rerio; data collection; metagenomics; microorganisms
Abstract:
... Data presented here contains metagenomic analysis regarding the sequential conventionalization of germ-free zebrafish embryos. Zebrafish embryos that underwent a germ-free sterilization process immediately after fertilization were promptly exposed to and raised to larval stage in conventional fish water. At 6 days postfertilization (dpf), these “conventionalized” larvae were compared to zebrafish ...
DOI:
10.1016/j.dib.2016.06.057
PubMed:
27508247
PubMed Central:
PMC4961299

10. 17-α-Ethinylestradiol modulates endocrine and behavioral responses to stress in zebrafish

Author:
Lurian Fenske; Ani Carla Concato; Ana Paula Vanin; Wagner Antonio Tamagno; Jéssica Reis de Oliveira Sofiatti; Helen Treichel; João Gabriel Santos da Rosa; Leonardo José Gil Barcellos; Rosilene R. Kaizer
Source:
Environmental science and pollution research international 2020 v.27 no.23 pp. 29341-29351
ISSN:
0944-1344
Subject:
Danio rerio; aggression; aquatic environment; contraceptives; endocrine-disrupting chemicals; pollution; predator-prey relationships; reproduction; research; social cohesion; steroid hormones; synthetic estrogens; tranquilizers
Abstract:
... The synthetic estrogen, 17-α-ethinylestradiol (EE2), present in contraceptive pills, is an endocrine-disrupting chemical (EDC) that can be found in the aquatic environment. We examined the impacts of EE2 on zebrafish behavioral and physiological responses through the novel tank test (NTT), which measures anxiety-like behavior; the mirror-induced aggression (MIA) test, which measures aggressiveness ...
DOI:
10.1007/s11356-020-09318-7

11. 17α-Ethinyl estradiol affects anxiety and shoaling behavior in adult male zebra fish (Danio rerio)

Author:
Nasim Reyhanian; Kristina Volkova; Stefan Hallgren; Tomas Bollner; Per-Erik Olsson; Håkan Olsén; Inger Porsch Hällström
Source:
Aquatic toxicology 2011 v.105 no.1-2 pp. 41-48
ISSN:
0166-445X
Subject:
Danio rerio; adults; anxiety; aquatic environment; brain; estradiol; fish; males; spawning; spermatogenesis; swimming; testes; unspecific monooxygenase; vitellogenin
Abstract:
... Ethinyl estradiol is a potent endocrine disrupting compound in fish and ubiquitously present in the aquatic environment. In this study, we exposed adult zebra fish (Danio rerio) males to 0, 5 or 25ng Ethinyl estradiol/L for 14 days and analyzed the effects on non-reproductive behavior. Effects of treatment of the exposed males was shown by vitellogenin induction, while brain aromatase (CYP 19B) ac ...
DOI:
10.1016/j.aquatox.2011.05.009
PubMed:
21684240

12. 17α-Ethinylestradiol decreases expression of multiple hepatic nucleotide excision repair genes in zebrafish (Danio rerio)

Author:
Notch, E.G.; Miniutti, D.M.; Mayer, G.D.
Source:
Aquatic toxicology 2007 v.84 no.3 pp. 301-309
ISSN:
0166-445X
Subject:
water pollution; messenger RNA; DNA damage; liver; biomarkers; laboratory animals; reverse transcriptase polymerase chain reaction; nucleotides; gene expression; animal models; DNA repair; fish; vitellogenin; Danio rerio; estradiol
Abstract:
... Waterborne 17α-ethinylestradiol (EE2) alters hormone-mediated biological indicators in fish. These alterations include increased plasma vitellogenin, increased intersex individuals, decreased egg and sperm production, reduced gamete quality, and complete feminization of male fish. Together, these observations implicate aquatic estrogens in a broad range of detrimental effects on fish reproduction ...
DOI:
10.1016/j.aquatox.2007.06.006

13. 17α-Ethinylestradiol disrupts the ontogeny of the forebrain GnRH system and the expression of brain aromatase during early development of zebrafish

Author:
Vosges, Mélanie; Le Page, Yann; Chung, Bon-chu; Combarnous, Yves; Porcher, Jean-Marc; Kah, Olivier; Brion, François
Source:
Aquatic toxicology 2010 v.99 no.4 pp. 479-491
ISSN:
0166-445X
Subject:
Danio rerio; brain; cytochrome P-450; early development; endocrine-disrupting chemicals; fish; genes; gonadotropin-releasing hormone; neuroglia; neurons; ontogeny; reproduction; steroids; unspecific monooxygenase
Abstract:
... Until now, studies dedicated to the actions of endocrine disrupting chemicals (EDCs) on the reproductive axis have been concerned with their effects at the gonadal level leaving their actions on neuroendocrine circuits controlling reproduction virtually unexplored. In vertebrates, gonadotropin-releasing hormone (GnRH) is the key factor controlling the activity of the reproductive axis. The develop ...
DOI:
10.1016/j.aquatox.2010.06.009

14. 17α-Ethinylestradiol hinders nucleotide excision repair in zebrafish liver cells

Author:
Notch, Emily G.; Mayer, Gregory D.
Source:
Aquatic toxicology 2009 v.95 no.4 pp. 273-278
ISSN:
0166-445X
Subject:
Danio rerio; estrogens; hormone receptors; hormone agonists; hormone antagonists; liver; DNA adducts; DNA damage; DNA repair; nucleotides; messenger RNA; lesions (animal)
Abstract:
... Nucleotide excision repair (NER) is the primary mechanism that removes bulky DNA adducts such as those caused by ubiquitous environmental mutagens including benzo(a)pyrene and other polycyclic aromatic hydrocarbons. Recent data suggest that exposure to environmentally relevant concentrations of estrogen decreases hepatic mRNA abundance of several key NER genes in adult zebrafish (Danio rerio). How ...
DOI:
10.1016/j.aquatox.2009.01.001

15. 17α-ethynilestradiol and tributyltin mixtures modulates the expression of NER and p53 DNA repair pathways in male zebrafish gonads and disrupt offspring embryonic development

Author:
Joana Soares; Teresa Neuparth; Angeliki Lyssimachou; Daniela Lima; Ana André; Maria A. Reis-Henriques; Luís Filipe C. Castro; António Paulo Carvalho; Nuno M. Monteiro; Miguel M. Santos
Source:
Ecological indicators 2018 v.95 pp. 1008-1018
ISSN:
1470-160X
Subject:
DNA repair; Danio rerio; ecotoxicology; eggs; embryogenesis; endocrine-disrupting chemicals; females; gene expression; genes; gonads; males; progeny; reproduction; risk assessment; screening; transcription (genetics); tributyltin; wildlife
Abstract:
... Although chemicals are usually present in the environment in complex mixtures, ecotoxicological risk assessments often rely on data from single exposures to contaminants. The present study aimed at examining the effects of two ubiquitous endocrine disrupting chemicals (EDCs), 17α-ethynilestradiol (EE2) and tributyltin (TBT), single and combined, in zebrafish (Danio rerio) reproduction and embryoni ...
DOI:
10.1016/j.ecolind.2017.04.054

16. 17β-Estradiol and the glucocorticoid clobetasol propionate affect the blood coagulation cascade in zebrafish

Author:
Simon Schmid; Karl Fent
Source:
Environmental pollution 2020 v.259 pp. 113808
ISSN:
0269-7491
Subject:
Danio rerio; adverse effects; aquatic environment; blood coagulation; coagulation; contraception; embryo (animal); estradiol; factor VII; fibrinogen; fish; gene expression; gene expression regulation; glucocorticoids; messenger RNA; progestational hormones; propionic acid
Abstract:
... Fish are exposed to estrogens, progestins and glucocorticoids in the aquatic environment but effects on the blood coagulation cascade are unknown. Here we analyzed effects of 17β-estradiol (E2) alone and in combination with mixtures of new generation progestins and the glucocorticoid clobetasol propionate (CLO) in zebrafish embryos to assess their effects on the blood coagulation system. We assess ...
DOI:
10.1016/j.envpol.2019.113808

17. 17β-Estradiol inhibits chondrogenesis in the skull development of zebrafish embryos

Author:
Fushimi, Shigeko; Wada, Naoyuki; Nohno, Tsutomu; Tomita, Masafumi; Saijoh, Kiyofumi; Sunami, Shigeo; Katsuyama, Hironobu
Source:
Aquatic toxicology 2009 v.95 no.4 pp. 292-298
ISSN:
0166-445X
Subject:
hormone receptors; chondrogenesis; signal transduction; gene expression; developmental toxicity; hormone antagonists; fish; Danio rerio; embryogenesis; estradiol; mortality; skull
Abstract:
... 17β-Estradiol (E2) plays important roles in the development and differentiation of the gonad and central nervous systems, but little is known regarding the effects of exogenous E2 on chondrogenesis in skeletal development. In the present study, we found that treatment with E2 1-5 days post-fertilization (dpf) at concentrations above 1.5×10⁻⁵ M increased the mortality rate in zebrafish embryos. Mor ...
DOI:
10.1016/j.aquatox.2009.03.004

18. 17β-Trenbolone binds to androgen receptor, decreases number of primordial germ cells, modulates expression of genes related to sexual differentiation, and affects sexual differentiation in zebrafish (Danio rerio)

Author:
Hua Tian; Rui Liu; Suqiu Zhang; Shuhui Wei; Wei Wang; Shaoguo Ru
Source:
Science of the total environment 2022 v.806 pp. 150959
ISSN:
0048-9697
Subject:
Danio rerio; androgen receptors; energy; environment; enzyme-linked immunosorbent assay; fish; fluorescence; genetically modified organisms; hybridization; quantitative polymerase chain reaction; sex ratio; sexual development; testes; vitellogenin
Abstract:
... Exposure to 17β-trenbolone caused a skewed sex ratio in fish. However, the molecular initiating event and key molecular event(s) remain unknown. In this study, zebrafish were exposed to 17β-trenbolone at nominal concentrations of 2 ng/L, 20 ng/L, 200 ng/L, and 2000 ng/L from fertilization to 60 days post fertilization (dpf). First, the sex ratio at 60 dpf was calculated to evaluate adverse outcome ...
DOI:
10.1016/j.scitotenv.2021.150959

19. 1H NMR based metabolomic profiling of early life stage zebrafish (Danio rerio) exposed to a water-soluble fraction of weathered sediment-bound diluted bitumen

Author:
Kaden K. Fujita; Zhe Xia; Gregg Tomy; Tony Montina; Steve Wiseman
Source:
Aquatic toxicology 2021 v.232 pp. 105766
ISSN:
0166-445X
Subject:
Danio rerio; alanine; aspartic acid; betaine; biosynthesis; bitumen; developmental stages; edema; fish; glutamic acid; glutamine; glycerol; inosine; lysine; metabolites; metabolomics; pericardium; phenylalanine; risk; sediments; serine; swim bladder; taurine; threonine; topology; toxicity; toxicology; transportation; tryptophan; tyrosine; water solubility; yolk sac
Abstract:
... Spills of diluted bitumen (dilbit) from pipelines pose a risk to the health of aquatic organisms, including fish, and with expected increases in production and transportation of dilbit, these risks could increase. To date, the majority of studies have investigated effects of fresh dilbit on aquatic organisms, but little is known about effects of weathered sediment-bound dilbit, including mechanism ...
DOI:
10.1016/j.aquatox.2021.105766

20. 1H NMR-based metabolomics analysis of adult zebrafish (Danio rerio) after exposure to diniconazole as well as its bioaccumulation behavior

Author:
Yao Wang; Wentao Zhu; Dezhen Wang; Miaomiao Teng; Jin Yan; Jiyan Miao; Zhiqiang Zhou
Source:
Chemosphere 2017 v.168 pp. 1571-1577
ISSN:
0045-6535
Subject:
Danio rerio; adults; alanine; amino acid metabolism; aquatic organisms; bioaccumulation; choline; creatine; diniconazole; enantiomers; energy metabolism; environmental assessment; glucose; histology; isoleucine; lactic acid; leucine; lipid metabolism; liver; metabolomics; spermatids; taurine; triazoles; valine
Abstract:
... As a systemic triazole fungicide, limited information is known about diniconazole. In this study, toxicological effects and bioaccumulation behavior of diniconazole in zebrafish were both evaluated to perform an overall assessment of its environmental risk towards aquatic organisms. The 1H NMR-based metabolomics analysis revealed that 70 μg L−1 diniconazole exposure increased valine, leucine, isol ...
DOI:
10.1016/j.chemosphere.2016.11.157