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- Wywial, Ewa, et al. Show all 9 Authors
- Nucleic acids research 2011 v.39 no.14 pp. 5991-6001
- DNA; Escherichia coli; Salmonella Typhimurium; antagonism; databases; epigenetics; genes; genotoxicity; loci; methyltransferases; restriction endonucleases; screening
- ... The Mrr protein of Escherichia coli is a laterally acquired Type IV restriction endonuclease with specificity for methylated DNA. While Mrr nuclease activity can be elicited by high-pressure stress in E. coli MG1655, its (over)expression per se does not confer any obvious toxicity. In this study, however, we discovered that Mrr of E. coli MG1655 causes distinct genotoxicity when expressed in Salmo ...
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