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- Zhang, Lv‐zhao, et al. Show all 7 Authors
- Phytotherapy research 2016 v.30 no.11 pp. 1886-1892
- Ginkgo biloba; biotransformation; cerebrovascular disorders; dose response; in vitro studies; liver microsomes; medicine; metabolites; pharmacokinetics; rats
- ... Ginkgo biloba extract (GBE), a traditional herbal product used worldwide as both medicine and supplement, is often supplied with clopidogrel for the treatment of cerebrovascular diseases. The aim of the current study was to explore the effect of GBE on the metabolism and pharmacokinetics of clopidogrel. The in vitro study using rat liver microsomes revealed that GBE significantly induced the conve ...