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- Author:
- Pongri, Adarki; Igbe, Ighodaro
- Source:
- Herba Polonica 2017 v.63 no.3 pp. 35-47
- ISSN:
- 0018-0599
- Subject:
- Grewia mollis, etc ; bark; blood serum; body weight changes; cough; diarrhea; fever; food intake; heart; histopathology; kidneys; lethal dose 50; liver; lungs; oral administration; rats; rickets; spleen; traditional medicine; Show all 19 Subjects
- Abstract:
- ... Introduction: Different parts of Grewia mollis Juss. (Malvaceae) are commonly used in folk medicine to treat several ailments, including diarrhea, ulcers, rickets, cough and fever. Although several studies have proved its therapeutic effectiveness, there are very few toxicological studies on the plant. Objectives: This study was carried out to evaluate the acute and sub-chronic toxicity of the aqu ...
- DOI:
- 10.1515/hepo-2017-0017
-
http://dx.doi.org/10.1515/hepo-2017-0017
- Author:
- Molander, Marianne; Nielsen, Line; Søgaard, Søren; Staerk, Dan; Rønsted, Nina; Diallo, Drissa; Chifundera, Kusamba Zacharie; van Staden, Johannes; Jäger, Anna K.
- Source:
- Journal of ethnopharmacology 2014 v.157 pp. 171-180
- ISSN:
- 0378-8741
- Subject:
- Grewia mollis, etc ; Bauhinia thonningii; Bitis arietans; Combretum; Lannea; Naja; Strychnos; active ingredients; antiserum; bioassays; enzyme inhibition; enzyme inhibitors; ethanol; hyaluronoglucosaminidase; inhibitory concentration 50; mortality; necrosis; patients; phospholipase A2; plant anatomy; polyphenols; proteinases; snake bites; snakes; traditional medicine; Democratic Republic of the Congo; Mali; South Africa; Show all 28 Subjects
- Abstract:
- ... Snakebite envenomation, every year, causes estimated 5–10,000 mortalities and results in more than 5–15,000 amputations in sub-Saharan Africa alone. Antiserum is not easily accessible in these regions or doctors are simply not available, thus more than 80% of all patients seek traditional practitioners as first-choice. Therefore it is important to investigate whether the plants used in traditional ...
- DOI:
- 10.1016/j.jep.2014.09.027
-
http://dx.doi.org/10.1016/j.jep.2014.09.027
- Author:
- Pearman, N.; Moxon, S.R.; Carnachan, S.M.; Cooke, M.E.; Nep, E.I.; Sims, I.M.; Morris, G.A.; Smith, A.M.
- Source:
- Bioactive carbohydrates and dietary fibre 2019 v.20 pp. 100201
- ISSN:
- 2212-6198
- Subject:
- Grewia mollis, etc ; bark; chemotaxis; collagen; dietary fiber; fibroblasts; genes; histology; leaves; messenger RNA; polysaccharides; quantitative polymerase chain reaction; staining; tissue repair; traditional medicine; Show all 15 Subjects
- Abstract:
- ... The Malvaceae family is a group of flowering plants that include approximately 244 genera, and 4225 species. Grewia mollis, and Hoheria populnea (lacebark), are examples of the Malvaceae family that are used in traditional medicine. For this study polysaccharide samples were extracted from the inner bark of Grewia mollis (unmodified (GG) and destarched grewia gum (GGDS)) and from the leaves of Hoh ...
- DOI:
- 10.1016/j.bcdf.2019.100201
-
https://dx.doi.org/10.1016/j.bcdf.2019.100201
- Author:
- Molander, Marianne; Staerk, Dan; Mørck Nielsen, Hanne; Brandner, Johanna M.; Diallo, Drissa; Kusamba Zacharie, Chifundera; van Staden, Johannes; Jäger, Anna K.
- Source:
- Journal of ethnopharmacology 2015 v.165 pp. 1-8
- ISSN:
- 0378-8741
- Subject:
- Grewia mollis, etc ; Dichrostachys cinerea; Paullinia pinnata; Tamarindus indica; antiserum; cell movement; cytotoxicity; enzymes; ethanol; models; mortality; necrosis; plant extracts; snake bites; therapeutics; tissue repair; traditional medicine; venoms; Sub-Saharan Africa; Show all 19 Subjects
- Abstract:
- ... Snakebite envenomation causes 5000–10,000 mortalities and results in more than 5–15,000 amputations in sub-Saharan Africa alone every year. The inaccessibility of antiserum therapy is a vast problem, and only about 2.5% of the actual need for antiserum in Africa is covered. Numerous plants have shown in vitro inhibitory activity against one or more of the hydrolytic enzymes involved in snakebite-i ...
- DOI:
- 10.1016/j.jep.2015.02.014
-
http://dx.doi.org/10.1016/j.jep.2015.02.014