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- Wantuch, Holly A., et al. Show all 7 Authors
- BMC biotechnology 2016 v.16 no.1 pp. 30
- Lucilia sericata; adults; antimicrobial peptides; cell proliferation; cost effectiveness; debridement; diabetic foot; diet; genetic engineering; health services; heat stress; hemolymph; humans; insect larvae; messenger RNA; patients; platelet-derived growth factor; platelet-derived growth factor receptors; polymerase chain reaction; proteins; secretion; tetracycline; tissue repair; transgenes; transgenic insects; United States
- ... BACKGROUND: Diabetes and its concurrent complications impact a significant proportion of the population of the US and create a large financial burden on the American health care system. FDA-approved maggot debridement therapy (MDT), the application of sterile laboratory-reared Lucilia sericata (green bottle fly) larvae to wounds, is a cost-effective and successful treatment for diabetic foot ulcer ...
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- Wantuch, Holly A., et al. Show all 5 Authors
- Insect biochemistry and molecular biology 2014 v.51 pp. 80-88
- Cochliomyia hominivorax; Drosophila; Lucilia cuprina; Lucilia sericata; chromosome aberrations; color; death; females; field experimentation; fluorescence; gene overexpression; genes; genetic markers; instars; larvae; livestock; males; mass rearing; pests; pupae; sex determination analysis; sterile insect technique; tetracycline; transactivators; transgenic insects; Australia
- ... The New World screwworm and the Australian sheep blowfly Lucilia cuprina are devastating pests of livestock. The larvae of these species feed on the tissue of the living animal and can cause death if untreated. The sterile insect technique or SIT was used to eradicate screwworm from North and Central America. This inspired efforts to develop strains containing complex chromosomal rearrangements fo ...