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You searched for: Author "Kavanová, Lenka" Remove constraint Author: "Kavanová, Lenka" Subject Porcine reproductive and respiratory syndrome virus Remove constraint Subject: Porcine reproductive and respiratory syndrome virus
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1. Concurrent infection of monocyte-derived macrophages with porcine reproductive and respiratory syndrome virus and Haemophilus parasuis: A role of IFNα in pathogenesis of co-infections

Author:
Kavanová, Lenka,   et al.   ; Matiašková, Katarína; Levá, Lenka; Nedbalcová, Kateřina; Matiašovic, Ján; Faldyna, Martin; Salát, Jiří;     Show all 7 Authors
Source:
Veterinary microbiology 2018 v.225 pp. 64-71
ISSN:
0378-1135
Subject:
Haemophilus parasuis; Porcine reproductive and respiratory syndrome virus; bacterial infections; immune response; inflammation; interleukin-1beta; interleukin-8; macrophages; mixed infection; models; pathogenesis; porcine reproductive and respiratory syndrome; swine
Abstract:
... Porcine reproductive and respiratory syndrome virus (PRRSV) predisposes pigs to secondary bacterial infection caused by Haemophilus parasuis. The aim of the present study was to analyse the immune response of monocyte-derived macrophages (MDMs), serving as a model of macrophages accumulating at the site of inflammation. The second part of the study was focused on the role of IFNα in the production ...
DOI:
10.1016/j.vetmic.2018.09.016

2. Concurrent infection with porcine reproductive and respiratory syndrome virus and Haemophilus parasuis in two types of porcine macrophages: apoptosis, production of ROS and formation of multinucleated giant cells

Author:
Kavanová, Lenka,   et al.   ; Matiašková, Katarína; Levá, Lenka; Štěpánová, Hana; Nedbalcová, Kateřina; Matiašovic, Ján; Faldyna, Martin; Salát, Jiří;     Show all 8 Authors
Source:
Veterinary research 2017 v.48 no.1 pp. 28
ISSN:
1297-9716
Subject:
giant cells; messenger RNA; Porcine reproductive and respiratory syndrome virus; porcine reproductive and respiratory syndrome; monocytes; respiratory tract diseases; macrophages; inflammation; pathogens; Haemophilus parasuis; cytopathogenicity; mortality; viruses; lungs; mixed infection; bacterial infections; apoptosis; swine
Abstract:
... Porcine reproductive and respiratory syndrome (PRRS) is one of the most significant and economically important infectious diseases affecting swine worldwide and can predispose pigs to secondary bacterial infections caused by, e.g. Haemophilus parasuis. The aim of the presented study was to compare susceptibility of two different types of macrophages which could be in contact with both pathogens du ...
DOI:
10.1186/s13567-017-0433-6
PubMed:
28472979
PubMed Central:
PMC5418695

3. Immune response of porcine alveolar macrophages to a concurrent infection with porcine reproductive and respiratory syndrome virus and Haemophilus parasuis in vitro

Author:
Kavanová, Lenka,   et al.   ; Prodělalová, Jana; Nedbalcová, Kateřina; Matiašovic, Ján; Volf, Jiří; Faldyna, Martin; Salát, Jiří;     Show all 7 Authors
Source:
Veterinary microbiology 2015 v.180 no.1-2 pp. 28-35
ISSN:
0378-1135
Subject:
Haemophilus parasuis; Porcine reproductive and respiratory syndrome virus; additive effect; bacteria; gene expression; immune response; immunopathology; interleukin-1beta; interleukin-8; macrophages; mixed infection; pathogens; reactive oxygen species; respiratory tract diseases; swine; tumor necrosis factor-alpha
Abstract:
... Porcine reproductive and respiratory syndrome virus (PRRSV) can predispose pigs to secondary respiratory infection with bacteria such as Haemophilus parasuis. Animals infected with both pathogens develop more severe clinical disease. The immune response of porcine alveolar macrophages (PAMs) to simultaneous infection with PRRSV and H. parasuis was analysed in vitro, describing cytokine production, ...
DOI:
10.1016/j.vetmic.2015.08.026