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1. Huo Xue Tong Luo capsule ameliorates osteonecrosis of femoral head through inhibiting lncRNA-Miat

Author:
Lin, Dingkun,   et al.   ; Fang, Bin; Li, Ying; Chen, Chen; Wei, Qiushi; Zheng, Jiaqian; Liu, Yamei; He, Wei; Li, Gang; Hou, Yonghui; Xu, Liangliang;     Show all 11 Authors
Source:
Journal of ethnopharmacology 2019 v.238 pp. 111862
ISSN:
0378-8741
Subject:
Angelica sinensis; Carthamus tinctorius; Ligusticum; Oriental traditional medicine; RNA; alizarin; bone formation; bone marrow; femur; genes; hips; histones; mesenchymal stromal cells; osteonecrosis; osteoporosis; pathogenesis; patients; peaches; promoter regions; quantitative polymerase chain reaction; rats; staining; surgery; transcription (genetics)
Abstract:
... Traditional Chinese medicine has a long history of treating various bone diseases including osteoporosis and osteonecrosis etc. In clinical treatment, Huo Xue Tong Luo capsule (HXTL capsule) containing Peach kernel, Safflower carthamus, Angelica sinensis, Ligusticum wallichii etc, is one of the mostly used prescriptions for treating osteonecrosis of the femoral head (ONFH) with promising effects.T ...
DOI:
10.1016/j.jep.2019.111862