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- Yuan, Xiangwei, et al. Show all 6 Authors
- Molecular immunology 2018 v.96 pp. 8-18
- Rheum palmatum; actin; bone resorption; drugs; emodin; histology; in vitro culture; inflammation; mice; micro-computed tomography; orthopedics; osteoclasts; phosphorylation; staining; surgeons; titanium; transcription factor NF-kappa B
- ... Aseptic loosening due to wear particles is a serious challenge for orthopedic surgeons, sabotaging the long-term success of total joint arthroplasty. The existing treatments for aseptic loosening are still far from satisfactory, necessitating more aggressive drug exploration. Here, we examined the effect of emodin on titanium particle-induced osteolysis and further investigated its underlying mech ...