Subject term: Staphylococcus aureus and Streptomyces

1. Additional pyrrolomycins from cultures of Streptomyces fumanus

Author:: Charan, R.D.; Schlingmann, G.; Bernan, V.S.; Feng, X.; Carter, G.T.
Source:: Journal of natural products 2005 v.68 no.2 pp. 277-279
ISSN:: 0163-3864
Subject:: Streptomyces fumanus; pyrroles; antibiotics; chemical structure; spectral analysis; antibacterial properties; Staphylococcus aureus; Enterococcus faecium; Escherichia coli
DOI:: 10.1021/np0496542
PubMed:: 15730262
: https://doi.org/10.1021/np0496542

2. Aldgamycins J–O, 16-Membered Macrolides with a Branched Octose Unit from Streptomycetes sp. and Their Antibacterial Activities

Author:: Wang Chuan-Xi; Ding Rong; Jiang Shu-Tai; Tang Jin-Shan; Hu Dan; Chen Guo-Dong; Lin Feng; Hong Kui; Yao Xin-Sheng; Gao Hao
Source:: Journal of natural products 2016 v.79 no.10 pp. 2446-2454
ISSN:: 1520-6025
Subject:: Aspergillus niger; Candida albicans; Escherichia coli; Staphylococcus aureus; Streptomyces; X-ray diffraction; antibacterial properties; fungi; macrolides; spectroscopy; structure-activity relationships; sugars
Abstract:: ... Six new 16-membered macrolides with a rare branched octose unit, aldgamycins J–O (1–6), along with two known compounds, swalpamycin B (7) and chalcomycin (8), were isolated from Streptomyces sp. HK-2006-1. Their structures were determined by detailed spectroscopic and X-ray crystallographic analysis. Natural products containing branched sugar units are rare. Aldgaropyranose and decarboxylated aldg ...
DOI:: 10.1021/acs.jnatprod.6b00200
: https://doi.org/10.1021/acs.jnatprod.6b00200

3. Angucycline antibiotics and its derivatives from marine-derived actinomycete Streptomyces sp. A6H

Author:: Zhijuan Hu; Lele Qin; Qianqian Wang; Wanjing Ding; Zhen Chen; Zhongjun Ma
Source:: Natural product research 2016 v.30 no.22 pp. 2551-2558
ISSN:: 1478-6427
Subject:: Staphylococcus aureus; Streptomyces; anti-infective properties; antibiotics; culture media; cytotoxicity; fermentation; hydrolysis; inhibitory concentration 50; methanolysis
Abstract:: ... Vineomycin A ₁ (1) and B ₂ (2) were isolated from the culture broth of marine actinomycete Streptomyces sp. A6H. Five hydrolysis products were obtained by rational hydrolysis and methanolysis of the fermentation extract. Their structures were characterised as aquayamycin (3), vineomycinone B ₂ (4), 9-C- D-olivosyltetrangulol (5), 7-O-methylgaltamycinone (6) and vineomycinone B ₂ methyl ester (7). ...
DOI:: 10.1080/14786419.2015.1120730
: https://doi.org/10.1080/14786419.2015.1120730

4. Antibacterial Activity of Streptomyces SAE4034 Isolated from Segara Anakan Mangrove Rhizosphere against Antibiotic Resistant Bacteria

Author:: Dini Ryandini; Hendro Pramono; Sukanto
Source:: Biosaintifika 2018 v.10 no.1 pp. 117-124
ISSN:: 2338-7610
Subject:: Enterobacter cloacae; Enterococcus; Escherichia coli; Klebsiella pneumoniae; Pseudomonas aeruginosa; Rhizophora apiculata; Staphylococcus aureus; Streptomyces; antibacterial properties; antibiotic resistance; antibiotics; bioactive compounds; genes; nucleotide sequences; phylogeny; physiology; rhizosphere; thin layer chromatography
Abstract:: ... Actinomycetes SAE4034 isolates was isolated from Rhizophora apiculata rhizosphere mud showed some antibacterial properties. The antibacterial ability of this isolate has not been tested on antibiotic resistant bacterial pathogens. However, there was no research has been reported regarding actinomycetes from Segara Anakan mangrove area resulting compounds inhibit the growth of antibiotics-resistant ...
DOI:: 10.15294/biosaintifika.v10i1.12896
: https://doi.org/10.15294/biosaintifika.v10i1.12896

5. Antibacterial Activity of Streptomyces sp. VITMK1 Isolated from Mangrove Soil of Pichavaram, Tamil Nadu, India

Author:: Manickavelu Manimaran; Jannu Vinay Gopal; Krishnan Kannabiran
Source:: Proceedings of the National Academy of Sciences, India, Section B: biological sciences 2017 v.87 no.2 pp. 499-506
ISSN:: 0369-8211
Subject:: Bacillus cereus; Fourier transform infrared spectroscopy; Proteus vulgaris; Salmonella; Staphylococcus aureus; Streptomyces; antibacterial properties; antibiotics; carbon; chloroform; ethyl acetate; gas chromatography-mass spectrometry; gel chromatography; hydrogen; mangrove soils; molecular weight; nuclear magnetic resonance spectroscopy; nucleotide sequences; solvents; India
Abstract:: ... The aim of the present study was to isolate antibacterial compound from Streptomyces sp. VITMK1 isolated from mangrove soil of Pichavaram, Tamil Nadu, India. A total of 31 actinomycetes isolates were isolated from soil samples collected at the mangrove region. Actinomycetes isolates were screened for antibacterial activity by well diffusion method. The potential isolate was identified and characte ...
DOI:: 10.1007/s40011-015-0619-5
: https://doi.org/10.1007/s40011-015-0619-5

6. Antibacterial Cyclic Lipopeptide Enamidonins with an Enamide-Linked Acyl Chain from a Streptomyces Species

Author:: Sangkeun Son; Sung-Kyun Ko; Seung Min Kim; Eun Kim; Gil Soo Kim; Byeongsan Lee; In-Ja Ryoo; Won-Gon Kim; Jung-Sook Lee; Young-Soo Hong; Jae-Hyuk Jang; Jong Seog Ahn
Source:: Journal of natural products 2018 v.81 no.11 pp. 2462-2469
ISSN:: 1520-6025
Subject:: Gram-positive bacteria; Staphylococcus aureus; Streptomyces; acetone; amino acids; antibacterial properties; antibiotic resistance; derivatization; linkage groups; lipopeptides; liquid chromatography; mass spectrometry; methicillin; nuclear magnetic resonance spectroscopy; Korean Peninsula
Abstract:: ... Three cyclic lipopeptides, including one known (1) and two new (2 and 3) compounds, that possess the rare enamide linkage group were discovered from Streptomyces sp. KCB14A132, an actinobacterium isolated from a soil sample collected from Jeung Island, Korea. The NMR and MS-based characterization showed that they differed in the amino acid residues in the peptide backbone. Application of Marfey’s ...
DOI:: 10.1021/acs.jnatprod.8b00497
: https://doi.org/10.1021/acs.jnatprod.8b00497

7. Antibacterial Meroterpenoids, Merochlorins G–J from the Marine Bacterium Streptomyces sp.

Author:: Min-Ji Ryu; Prima F. Hillman; Jihye Lee; Sunghoon Hwang; Eun-Young Lee; Sun-Shin Cha; Inho Yang; Dong-Chan Oh; Sang-Jip Nam; William Fenical
Source:: Marine drugs 2021 v.19 no.11 pp. -
ISSN:: 1660-3397
Subject:: Bacillus subtilis; Kocuria rhizophila; Staphylococcus aureus; Streptomyces; aquatic bacteria; circular dichroism spectroscopy; enantiomers; marine sediments; meroterpenoids; spectral analysis
Abstract:: ... Four new chlorinated meroterpenoids, merochlorins G−J (1−4), and 10, a dihydronaphthalenedione precursor, along with known merochlorins A (5) and C−F (6−9), were obtained from cultivation of the bacterium strain Streptomyces sp. CNH-189, which was isolated from marine sediment. The planar structures of compounds 1−4 and 10 were elucidated by interpretation of MS, UV, and NMR spectroscopic data. Th ...
DOI:: 10.3390/md19110618
: https://doi.org/10.3390/md19110618

8. Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471

Author:: Zheng Cui; Xiachang Wang; Stefan Koppermann; Jon S. Thorson; Christian Ducho; Steven G. Van Lanen
Source:: Journal of natural products 2018 v.81 no.4 pp. 942-948
ISSN:: 1520-6025
Subject:: Aquifex; Escherichia coli; Staphylococcus aureus; Streptomyces; antibacterial properties; antibiotics; fatty acids; inhibitory concentration 50; mutagenesis; mutants; nuclear magnetic resonance spectroscopy; nucleosides; spectral analysis
Abstract:: ... Muraymycins are nucleoside antibiotics isolated from Streptomyces sp. NRRL 30471 and several mutant strains thereof that were generated by random, chemical mutagenesis. Reinvestigation of two mutant strains using new media conditions led to the isolation of three new muraymycin congeners, named B8, B9, and C6 (1–3), as well as a known muraymycin, C1. Structures of the compounds were elucidated by ...
DOI:: 10.1021/acs.jnatprod.7b01054
PubMed:: 29553733
PubMed Central:: PMC6434714
: https://doi.org/10.1021/acs.jnatprod.7b01054

9. Antibacterial and antifungal activities of polyketide metabolite from marine Streptomyces sp. AP-123 and its cytotoxic effect

Author:: Mariadhas Valan Arasu; Veeramuthu Duraipandiyan; Savarimuthu Ignacimuthu
Source:: Chemosphere 2013 v.90 pp. 479-487
ISSN:: 0045-6535
Subject:: Aspergillus niger; Bacillus subtilis; Candida albicans; Escherichia coli; Gram-negative bacteria; Gram-positive bacteria; Pseudomonas aeruginosa; Staphylococcus aureus; Streptomyces flavogriseus; antibacterial properties; antifungal properties; bioinformatics; cell walls; chromatography; cytotoxicity; ethyl acetate; fungi; genes; hexane; hydrolysates; kidneys; metabolites; minimum inhibitory concentration; monkeys; nuclear magnetic resonance spectroscopy; phylogeny; polyketide synthases; polyketides; ribosomal DNA; screening; sequence homology; solvents; spectral analysis; streptomycin; India
Abstract:: ... A Gram positive, filamentous, spore forming antagonistic Streptomyces sp. AP-123 derived from marine region of Andra Pradesh, India, was studied for its medical importance. Among the 210 Streptomyces strains screened at 64.3% exhibited activity against Gram positive bacteria, 48.5% showed activity towards Gram negative bacteria, 38.8% exhibited both Gram positive and negative bacteria and 80.85% s ...
DOI:: 10.1016/j.chemosphere.2012.08.006
PubMed:: 22963878
: https://doi.org/10.1016/j.chemosphere.2012.08.006

10. Antibacterial, antioxidant and anticancer activities of biphenyls from Streptomyces sp. BO-07: an endophyte in Boesenbergia rotunda (L.) Mansf A.

Author:: Thongchai Taechowisan; Suchanya Chaisaeng; Waya S. Phutdhawong
Source:: Food and agricultural immunology 2017 v.28 no.6 pp. 1330-1346
ISSN:: 1465-3443
Subject:: 2,2-diphenyl-1-picrylhydrazyl; Bacillus cereus; Bacillus subtilis; Gram-positive bacteria; Staphylococcus aureus; Streptomyces; antibacterial properties; antineoplastic activity; antioxidant activity; antioxidants; chemotaxonomy; cytotoxicity; endophytes; fractionation; inhibitory concentration 50; minimum inhibitory concentration; neoplasms; ribosomal DNA
Abstract:: ... Strain BO-07 was isolated from the root tissue of Boesenbergia rotunda (L.) Mansf A. and identified as Streptomyces sp. on the basis of morphology, chemotaxonomy and 16S rDNA sequencing. The fractionation of the crude extract from strain BO-07 cultures led to the isolation of two biphenyls: 3′-hydroxy-5-methoxy-3,4-methylenedioxybiphenyl (1) and 3′-hydroxy-5,5′-dimethoxy-3,4-methylenedioxybiphenyl ...
DOI:: 10.1080/09540105.2017.1339669
: https://doi.org/10.1080/09540105.2017.1339669

11. Antimicrobial Activities of Marine Sponge-Associated Bacteria

Author:: Yitayal S. Anteneh; Qi Yang; Melissa H. Brown; Christopher M. M. Franco
Source:: Microorganisms 2021 v.9 no.1 pp. -
ISSN:: 2076-2607
Subject:: Porifera; Staphylococcus aureus; Streptomyces; active ingredients; animal pathogenic bacteria; antibiotics; antifungal properties; fungi; marine environment; metabolites; multiple drug resistance; sampling; strains; symbionts; South Australia
Abstract:: ... The misuse and overuse of antibiotics have led to the emergence of multidrug-resistant microorganisms, which decreases the chance of treating those infected with existing antibiotics. This resistance calls for the search of new antimicrobials from prolific producers of novel natural products including marine sponges. Many of the novel active compounds reported from sponges have originated from the ...
DOI:: 10.3390/microorganisms9010171
: https://doi.org/10.3390/microorganisms9010171

12. Antimicrobial Activity of Marine Bacterial Symbionts Retrieved from Shallow Water Hydrothermal Vents

Author:: Arnheidur Eythorsdottir; Sesselja Omarsdottir; Hjorleifur Einarsson
Source:: Marine biotechnology 2016 v.18 no.3 pp. 293-300
ISSN:: 1436-2228
Subject:: Anthozoa; Porifera; Staphylococcus aureus; Streptomyces; algae; alpha-Proteobacteria; anti-infective properties; bacteria; ethyl acetate; gamma-Proteobacteria; growth retardation; invertebrates; selective media; symbionts; Iceland
Abstract:: ... Marine sponges and other sessile macro-organisms were collected at a shallow water hydrothermal site in Eyjafjörður, Iceland. Bacteria were isolated from the organisms using selective media for actinomycetes, and the isolates were screened for antimicrobial activity. A total of 111 isolates revealed antimicrobial activity displaying different antimicrobial patterns which indicates production of va ...
DOI:: 10.1007/s10126-016-9695-7
: https://doi.org/10.1007/s10126-016-9695-7

13. Antimicrobial and Cytotoxicity Properties of 2,3-Dihydroxy-9,10-Anthraquinone Isolated from Streptomyces galbus (ERINLG-127)

Author:: C. Balachandran; Y. Arun; V. Duraipandiyan; S. Ignacimuthu; K. Balakrishna; N.A. Al-Dhabi
Source:: Applied biochemistry and biotechnology 2014 v.172 no.7 pp. 3513-3528
ISSN:: 0273-2289
Subject:: Staphylococcus aureus; acetates; enzymes; Salmonella Typhimurium; chromatography; forests; inhibitory concentration 50; Streptomyces galbus; Pseudomonas aeruginosa; antimicrobial properties; energy; minimum inhibitory concentration; adenocarcinoma; cytotoxicity; soil sampling; silica gel; fractionation; Klebsiella pneumoniae; anti-infective agents; bacteria; fungi; India
Abstract:: ... Streptomyces galbus ERINLG-127 was isolated from the soil samples of the Marapalam forest, Nilgiris, India. The ethyl acetate extract was subjected to activity-guided fractionation by column chromatography over silica gel. This led to the isolation of 2,3-dihydroxy-9,10-anthraquinone as the active principle. The compound showed good antimicrobial activity against tested bacteria and fungi. The min ...
DOI:: 10.1007/s12010-014-0783-8
PubMed:: 24549801
: https://doi.org/10.1007/s12010-014-0783-8

14. Antimicrobial and cytotoxic activity of silver nanoparticles synthesized from two haloalkaliphilic actinobacterial strains alone and in combination with antibiotics

Author:: M. Wypij; M. Świecimska; J. Czarnecka; H. Dahm; M. Rai; P. Golinska
Source:: Journal of applied microbiology 2018 v.124 no.6 pp. 1411-1424
ISSN:: 1364-5072
Subject:: Bacillus subtilis; Candida albicans; Escherichia coli; Fourier transform infrared spectroscopy; Malassezia furfur; Staphylococcus aureus; Streptomyces; antifungal agents; antimicrobial properties; bacteria; biofilm; cytotoxicity; fibroblasts; gentian violet; human cell lines; inhibitory concentration 50; kanamycin; mice; minimum inhibitory concentration; multiple drug resistance; nanomedicine; nanosilver; synergism; transmission electron microscopy; yeasts
Abstract:: ... AIMS: Presently, the effective antimicrobial agents have been limited by the emergence of microbial strains with multidrug resistance and biofilm formation potential. In the present study, we report remarkable antimicrobial activity of silver nanoparticles (AgNPs) synthesized from Streptomyces calidiresistens IF11 and IF17 strains, including inhibition of biofilm formation and synergistic effect o ...
DOI:: 10.1111/jam.13723
: https://doi.org/10.1111/jam.13723

15. Antimicrobial investigation of selected soil actinomycetes isolated from unexplored regions of Kashmir Himalayas, India

Author:: Aabid Manzoor Shah; Shakeel-u-Rehman; Aehtesham Hussain; Saleem Mushtaq; Muzafar Ahmad Rather; Aiyatullah Shah; Zahoor Ahmad; Inshad Ali Khan; Khursheed Ahmad Bhat; Qazi Parvaiz Hassan
Source:: Microbial pathogenesis 2017 v.110 pp. 93-99
ISSN:: 0882-4010
Subject:: Mycobacterium tuberculosis; Staphylococcus aureus; Streptomyces; animal pathogens; antibacterial properties; antibiotics; chromatography; ethyl acetate; industrial applications; secondary metabolites; soil; soil bacteria; spectral analysis; India
Abstract:: ... The aim of the present study was to isolate and evaluate the antimicrobial potential of soil actinomycetes of Kashmir Himalayas. The secondary metabolites of actinomycetes are the prominent source of antibiotics. A total of 121 morphologically different actinomycete strains were isolated and screened for antimicrobial activity against various human pathogens. The ethyl acetate extract of fermented ...
DOI:: 10.1016/j.micpath.2017.06.017
: https://doi.org/10.1016/j.micpath.2017.06.017

16. Antimicrobial lavandulylated flavonoids from a sponge-derived actinomycete

Author:: Duc Danh Cao; Thi Quynh Do; Huong Doan Thi Mai; Quyen Vu Thi; Mai Anh Nguyen; Hong Minh Le Thi; Dang Thach Tran; Van Minh Chau; Do Cong Thung; Van Cuong Pham
Source:: Natural product research 2020 v.34 no.3 pp. 413-420
ISSN:: 1478-6427
Subject:: Bacillus cereus; Candida albicans; Enterococcus faecalis; Escherichia coli; Pseudomonas aeruginosa; Salmonella enterica; Staphylococcus aureus; Streptomyces; antimicrobial properties; circular dichroism spectroscopy; culture media; flavonoids; microorganisms; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:: ... Analysis of an antimicrobial culture broth extract of the sponge-derived actinomycete Streptomyces sp. (strain G246) led to the isolation of two new lavandulylated flavonoids, 6-lavandulyl-7-methoxy-5,2′,4′-trihydroxylflavanone (1) and 5′-lavandulyl-4′-methoxy-2,4,2′,6′-tetrahydroxylchalcone (2), along with eight known compounds 3–10. Their structures were established by spectral data analysis, in ...
DOI:: 10.1080/14786419.2018.1538219
: https://doi.org/10.1080/14786419.2018.1538219

17. Antimicrobial metabolites from a marine-derived Actinomycete Streptomyces sp. G278

Author:: Duc Tuan Cao; Van Hieu Tran; Van Nam Vu; Huong Doan Thi Mai; Thi Hong Minh Le; Thi Quyen Vu; Hung Huy Nguyen; Van Minh Chau; Van Cuong Pham
Source:: Natural product research 2019 v.33 no.22 pp. 3223-3230
ISSN:: 1478-6427
Subject:: Candida albicans; Enterococcus faecalis; Escherichia coli; Salmonella enterica; Staphylococcus aureus; Streptomyces; X-ray diffraction; antifungal properties; culture media; mass spectrometry; metabolites; microorganisms; nuclear magnetic resonance spectroscopy; spectral analysis; thiophene
Abstract:: ... Analysis of an antimicrobial extract prepared from culture broth of the marine-derived actinomycete Streptomyces sp. G278 led to the isolation of ten compounds, 1-10. Two compounds, 2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene (1), and 3-hydroxyl-2-methylpyridine (2) were isolated from a natural source for the first time. The structures of the isolated compounds were established by their spectral ...
DOI:: 10.1080/14786419.2018.1468331
: https://doi.org/10.1080/14786419.2018.1468331

18. Antitumour and antimicrobial activities of endophytic streptomycetes from pharmaceutical plants in rainforest

Author:: Li, J.; Zhao, G.-Z.; Chen, H.-H.; Wang, H.-B.; Qin, S.; Zhu, W.-Y.; Xu, L.-H.; Jiang, C.-L.; Li, W.-J.
Source:: Letters in applied microbiology 2008 v.47 no.6 pp. 574-580
ISSN:: 0266-8254
Subject:: Candida albicans; Escherichia coli; Klebsiella pneumoniae; Staphylococcus aureus; Staphylococcus epidermidis; Streptomyces; agar; anti-infective properties; antineoplastic activity; cytotoxicity; endophytes; ligases; polyketide synthases; polymerase chain reaction; rain forests; China
Abstract:: ... The aim of this study was to screen antitumour and antimicrobial activities of endophytic actinomycetes isolated from pharmaceutical plants in rainforest in Yunnan province, China. Antitumour activity was studied by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and antimicrobial activity was determined by agar well diffusion method. The high bioactive endophytic isolates w ...
DOI:: 10.1111/j.1472-765X.2008.02470.x
PubMed:: 19120929
: https://doi.org/10.1111/j.1472-765X.2008.02470.x

19. Arthroamide, a Cyclic Depsipeptide with Quorum Sensing Inhibitory Activity from Arthrobacter sp.

Author:: Igarashi Yasuhiro; Yamamoto Kazuki; Fukuda Takao; Shojima Akane; Nakayama Jiro; Carro Lorena; Trujillo Martha E.
Source:: Journal of natural products 2015 v.78 no.11 pp. 2827-2831
ISSN:: 1520-6025
Subject:: Arthrobacter; Staphylococcus aureus; Streptomyces; quorum sensing; sandstone; secondary metabolites
Abstract:: ... Nonfilamentous actinobacteria have been less studied as secondary metabolite producers than their filamentous counterparts such as Streptomyces. From our collection of nonfilamentous actinobacteria isolated from sandstone, an Arthrobacter strain was found to produce a new cyclic peptide arthroamide (1) together with the known compound turnagainolide A (2). These compounds inhibited the quorum sens ...
DOI:: 10.1021/acs.jnatprod.5b00540
: https://doi.org/10.1021/acs.jnatprod.5b00540

20. Azodyrecins A–C: Azoxides from a Soil-Derived Streptomyces Species

Author:: Mario Wibowo; Charlotte H. Gotfredsen; Elisa Sassetti; Jette Melchiorsen; Mads Hartvig Clausen; Lone Gram; Ling Ding
Source:: Journal of natural products 2020 v.83 no.12 pp. 3519-3525
ISSN:: 1520-6025
Subject:: Candida albicans; Staphylococcus aureus; Streptomyces; Vibrio anguillarum; alanine; cytotoxicity; humans; neoplasm cells
Abstract:: ... Azoxy compounds belong to a small group of natural products sharing a common functional group with the general structure RN = N⁺(O–)R. Three new azoxides, azodyrecins A–C (1–3), were isolated from a soil-derived Streptomyces sp. strain P8-A2. The cis-alkenyl unit in 1–3 was found to readily isomerize to the trans-congeners (4–6). The structures of the new compounds were determined by detailed spec ...
DOI:: 10.1021/acs.jnatprod.0c00339
: https://doi.org/10.1021/acs.jnatprod.0c00339

21. Bioactive potential of Streptomyces associated with marine sponges

Author:: Dharmaraj, Selvakumar; Sumantha, Alagarsamy
Source:: World journal of microbiology & biotechnology 2009 v.25 no.11 pp. 1971-1979
ISSN:: 0959-3993
Subject:: Aspergillus niger; Bacillus subtilis; Candida albicans; Escherichia coli; Mycale; Saccharomyces cerevisiae; Staphylococcus aureus; Streptomyces; Vibrio cholerae; absorbance; antifungal properties; screening; spectral analysis
Abstract:: ... The present work deals with isolation of Streptomyces associated with marine sponges and its bioactive potential. Streptomyces sp. were isolated from the marine sponges Callyspongia diffusa, Mycale mytilorum, Tedania anhelans and Dysidea fragilis. From the initial screening, 94 cultures of Streptomyces were obtained and from these 58 cultures exhibited antagonism against bacteria, 36 strains again ...
DOI:: 10.1007/s11274-009-0096-1
: https://doi.org/10.1007/s11274-009-0096-1

22. Biosynthesis of Silver Nanoparticles Using The Cell-Free Filtrate of Streptomyces atacamensis: Characterization and Antibacterial Activity

Author:: Arun Kumar Kulshrestha; Priti Hemant Patel
Source:: Applied biological research 2022 v.24 no.2 pp. 226-233
ISSN:: 0974-4517
Subject:: Bacillus cereus; Escherichia coli; Pseudomonas aeruginosa; Staphylococcus aureus; Streptomyces; antibacterial properties; biosynthesis; color; culture media; filtrates; genes; nanosilver; research; rivers; soil; zeta potential; India
Abstract:: ... A bacterial strain was isolated from a soil near the bank Tapi river, Surat (India) and identified as Streptomyces atacamensis AK3 on the basis of 16s rRNA gene sequencing. The strain possessed reducing agents which enabled it to produce silver nano-particles (AgNPs). The peak observed at 420 nm and turning the broth culture colour to brown indicated the synthesis of AgNPs. Zeta potential of -14 m ...
DOI:: 10.5958/0974-4517.2022.00031.3
: https://doi.org/10.5958/0974-4517.2022.00031.3

23. Biosynthesis of mercapturic acid derivative of the labdane-type diterpene, cyslabdan that potentiates imipenem activity against methicillin-resistant Staphylococcus aureus: cyslabdan is generated by mycothiol-mediated xenobiotic detoxification

Author:: Haruo Ikeda; Kazuo Shin-ya; Tohru Nagamitsu; Hiroshi Tomoda
Source:: Journal of industrial microbiology & biotechnology 2016 v.43 no.2-3 pp. 325-342
ISSN:: 1367-5435
Subject:: Staphylococcus aureus; Streptomyces; amidase; antibiotic resistance; biosynthesis; culture media; databases; genes; genome mining; heterologous gene expression; imipenem; metabolites; methicillin; mutants; mycelium; oxygen; transcription (genetics)
Abstract:: ... Genome mining of cyslabdan-producing Streptomyces cyslabdanicus K04-0144 revealed that a set of four genes, cldA, cldB, cldC, and cldD (the cld cluster), which formed a single transcriptional unit, were involved in the biosynthesis of cyslabdan that potentiates imipenem activity against methicillin-resistant Staphylococcus aureus. Experimental studies supported the heterologous expression of the c ...
DOI:: 10.1007/s10295-015-1694-6
: https://doi.org/10.1007/s10295-015-1694-6

24. Biosynthesis, characterization and antimicrobial activity of silver nanoparticles by Streptomyces sp. SS2

Author:: Yugal Kishore Mohanta; Sujit Kumar Behera
Source:: Bioprocess and biosystems engineering 2014 v.37 no.11 pp. 2263-2269
ISSN:: 1615-7591
Subject:: Bacillus subtilis; Escherichia coli; Fourier transform infrared spectroscopy; Staphylococcus aureus; Streptomyces; Vibrio cholerae; absorption; antibacterial properties; biosynthesis; conservation areas; nanoparticles; nanosilver; ribosomal DNA; scanning electron microscopy; secondary metabolites; sediments; silver; soil; zeta potential
Abstract:: ... In the present study the microbial biosynthesis of silver nanoparticles (AgNPs) by secondary metabolites of Streptomyces sp. SS2 in an eco-friendly approach has been reported. The Streptomyces sp. SS2 was isolated from the soil sediment of Similipal Biosphere Reserve. The identification of this strain was determined by phenotypical characteristics (morphological and biochemical) and molecular char ...
DOI:: 10.1007/s00449-014-1205-6
: https://doi.org/10.1007/s00449-014-1205-6

25. Broad-spectrum In vitro antimicrobial activities of Streptomyces sp. strain BCNU 1001

Author:: Hye Jung Choi; Dong Wan Kim; Young Whan Choi; Young Geun Lee; Yong-Ill Lee; Yong Kee Jeong; Woo Hong Joo
Source:: Biotechnology and bioprocess engineering 2012 v.17 no.3 pp. 576-583
ISSN:: 1226-8372
Subject:: Aspergillus niger; Bacillus subtilis; Candida albicans; Escherichia coli; Micrococcus luteus; Pseudomonas aeruginosa; Pseudomonas fluorescens; Saccharomyces cerevisiae; Staphylococcus aureus; Streptomyces; Trichophyton mentagrophytes; acetates; antimicrobial properties; forest soils; minimum inhibitory concentration; nuclear magnetic resonance spectroscopy; ribosomal DNA; soil sampling
Abstract:: ... Streptomyces sp. strain BCNU 1001 was isolated from forest soil samples. Cultural, morphological, and physiological characteristics as well as 16S rDNA analysis revealed that the isolate, BCNU 1001, belonged to the genus Streptomyces. The antimicrobial activity of the ethyl acetate extract was confirmed using the broth microdilution technique. The minimum inhibitory concentration (MIC) of the BCNU ...
DOI:: 10.1007/s12257-011-0151-2
: https://doi.org/10.1007/s12257-011-0151-2

26. Catalytic Site Cooperativity in Dimeric Methylthioadenosine Nucleosidase

Author:: Wang Shanzhi; Thomas Keisha; Schramm Vern L.
Source:: Biochemistry 2014 v.53 no.9 pp. 1527-1535
ISSN:: 1520-4995
Subject:: Campylobacter; Helicobacter; Staphylococcus aureus; Streptomyces; active sites; adenine; binding sites; catalytic activity; crystal structure; cysteine; enzymes; hydrolysis; menaquinones; quorum sensing; thermodynamics; titration
Abstract:: ... 5′-Methylthioadenosine/S-adenosylhomocysteine nucleosidases (MTANs) are bacterial enzymes that catalyze hydrolysis of the N-ribosidic bonds of 5′-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) to form adenine and 5-thioribosyl groups. MTANs are involved in AI-1 and AI-2 bacterial quorum sensing and the unusual futalosine-based menaquinone synthetic pathway in Streptomyces, Helicobacter ...
DOI:: 10.1021/bi401589n
PubMed:: 24502544
PubMed Central:: PMC3977580
: https://doi.org/10.1021/bi401589n

27. Comparative Analysis of Antimicrobial Activities of Valinomycin and Cereulide, the Bacillus cereus Emetic Toxin

Author:: Tempelaars, Marcel H.; Rodrigues, Susana; Abee, Tjakko
Source:: Applied and environmental microbiology 2011 v.77 no.8 pp. 2755-2762
ISSN:: 0099-2240
Subject:: Bacillus cereus; Bacillus subtilis; Gram-negative bacteria; Gram-positive bacteria; Listeria innocua; Listeria monocytogenes; Staphylococcus aureus; Streptomyces; aerobic conditions; anaerobic conditions; antimicrobial properties; ecological function; flow cytometry; membrane potential; pH; potassium; potassium chloride; protons; toxins; valinomycin
Abstract:: ... Cereulide and valinomycin are highly similar cyclic dodecadepsipeptides with potassium ionophoric properties. Cereulide, produced by members of the Bacillus cereus group, is known mostly as emetic toxin, and no ecological function has been assigned. A comparative analysis of the antimicrobial activity of valinomycin produced by Streptomyces spp. and cereulide was performed at a pH range of pH 5.5 ...
DOI:: 10.1128/AEM.02671-10
PubMed:: 21357430
PubMed Central:: PMC3126370
: https://doi.org/10.1128/AEM.02671-10

28. Comparative analysis of the relationship between translation efficiency and sequence features of endogenous proteins in multiple organisms

Author:: Naoyuki Tajima; Toshitaka Kumagai; Yutaka Saito; Tomoshi Kameda
Source:: Genomics 2021 v.113 no.4 pp. 2675-2682
ISSN:: 0888-7543
Subject:: Escherichia coli; Saccharomyces cerevisiae; Staphylococcus aureus; Streptomyces; codon usage; genomics; protein synthesis; ribosomes; sequence analysis; taxonomy
Abstract:: ... The translation efficiency of protein genes is known to be affected by sequence features. Previous studies have found that various sequence features based on codon usage and mRNA secondary structure contribute to translation efficiency. However, most studies have focused on a specific organism, usually a model organism such as Escherichia coli or Saccharomyces cerevisiae. Here, we investigate whet ...
DOI:: 10.1016/j.ygeno.2021.05.037
: https://doi.org/10.1016/j.ygeno.2021.05.037

29. Cyclic Hexapeptides from the Deep South China Sea-Derived Streptomyces scopuliridis SCSIO ZJ46 Active Against Pathogenic Gram-Positive Bacteria

Author:: Song Yongxiang; Li Qinglian; Liu Xue; Chen Yuchan; Zhang Yun; Sun Aijun; Zhang Weimin; Zhang Jingren; Ju Jianhua
Source:: Journal of natural products 2014 v.77 no.8 pp. 1937-1941
ISSN:: 1520-6025
Subject:: Gram-positive bacteria; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus; Streptomyces; antibacterial properties; antibiotic resistance; high performance liquid chromatography; methicillin; spectral analysis; structure-activity relationships; South China Sea
Abstract:: ... Three new cyclohexapeptides, desotamides B–D (2–4), and the known desotamide (1) were isolated from marine microbe Streptomyces scopuliridis SCSIO ZJ46. The sequences and absolute configurations of 2–4 were elucidated on the basis of high-resolution spectroscopic data, Marfey’s method, and chiral-phase HPLC data. Desotamide C (3) contains a unique N-formyl-kynurenine residue, whereas 4 lacks formy ...
DOI:: 10.1021/np500399v
: https://doi.org/10.1021/np500399v

30. Daryamides A-C, Weakly Cytotoxic Polyketides from a Marine-Derived Actinomycete of the Genus Streptomyces Strain CNQ-085

Author:: Asolkar, R.N.; Jensen, P.R.; Kauffman, C.A.; Fenical, W.
Source:: Journal of natural products 2006 v.69 no.12 pp. 1756-1759
ISSN:: 0163-3864
Subject:: Candida albicans; humans; cytotoxicity; antifungal properties; polyketides; cultured cells; spectral analysis; Streptomyces; chemical structure; stereochemistry; anticarcinogenic activity; California
DOI:: 10.1021/np0603828
PubMed:: 17190455
: https://doi.org/10.1021/np0603828

31. Detection of the antibacterial effect of Chaetomium cochliodes Palliser CCM F-232 based on agar plugs and unprocessed fungal substances from cultivation media

Author:: Katarína Chovanová; Marcel Zámocký
Source:: Biologia 2016 v.71 no.11 pp. 1204-1211
ISSN:: 1336-9563
Subject:: Aspergillus; Bacillus subtilis; Chaetomium globosum; Penicillium; Staphylococcus aureus; Streptomyces; adverse effects; agar; antibacterial properties; antibiotics; antimalarials; cytotoxicity; equipment; fungi; growth retardation; secondary metabolites
Abstract:: ... There is an increasing demand for novel antibiotics that are highly effective, but simultaneously reveal minimal side effects. Currently, major sources of antibiotics are found among bacterial genus Streptomyces and among fungal genera Penicillium and Aspergillus. Chaetomium represents the largest genus of the family Chaetomiaceae actually containing more than 100 described species. This rather co ...
DOI:: 10.1515/biolog-2016-0153
: https://doi.org/10.1515/biolog-2016-0153

32. Detection, selective isolation and characterisation of Dactylosporangium strains from diverse environmental samples

Author:: Byung-Yong Kim; Jenileima Devi Kshetrimayum; Michael Goodfellow
Source:: Systematic and applied microbiology 2011 v.34 no.8 pp. 606-616
ISSN:: 0723-2020
Subject:: Bacillus subtilis; DNA primers; Dactylosporangium; Kocuria rhizophila; Staphylococcus aureus; Streptomyces; clones; genes; gentamicin; growth retardation; habitats; phylogeny; polyketide synthases; polymerase chain reaction; ribosomal RNA; secondary metabolites
Abstract:: ... A culture-independent, nested PCR procedure based on genus-specific oligonucleotide primers detected the presence of members of the genus Dactylosporangium in 14 out of 21 diverse environmental samples. Clones generated from the 14 positive environmental samples formed distinct phyletic lines in the dactylosporangial 16S rRNA gene tree. Presumptive dactylosporangiae were isolated from 7 of these s ...
DOI:: 10.1016/j.syapm.2011.03.008
: https://doi.org/10.1016/j.syapm.2011.03.008

33. Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15

Author:: Ram Hari Dahal; Tuan Manh Nguyen; Dong Seop Shim; Joon Young Kim; Jangyul Lee; Jaisoo Kim
Source:: Antioxidants 2020 v.9 no.4 pp. -
ISSN:: 2076-3921
Subject:: 2,2-diphenyl-1-picrylhydrazyl; Bacillus subtilis; Escherichia coli; Gram-negative bacteria; Propionibacterium acnes; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis; Streptomyces; active ingredients; animal pathogenic bacteria; antimicrobial properties; antioxidant activity; antioxidants; biomedical research; cell lines; cell proliferation; collagen; computer software; cosmetics; cytotoxicity; elastase; enzyme inhibition; image analysis; mushrooms; porous media; roughness; silica; skin (animal)
Abstract:: ... Various cosmetics having a single function are increasingly being used, but cosmetics having multifunctional activities remain limited. We aimed to develop a multifunctional cosmetic cream having antioxidant, anti-tyrosinase, anti-aging and antimicrobial activities. Antimicrobial activities were performed by disc-diffusion method. Cell toxicity and cell proliferations were evaluated in a 96-well p ...
DOI:: 10.3390/antiox9040278
: https://doi.org/10.3390/antiox9040278

34. Discovery and evaluation on the antibacterial and cytotoxic activities of a novel antifungalmycin N2 produced from Streptomyces sp. strain N2

Author:: Liang Yao; Qun Liu; Zhi-Min Wu; Kun-Tai Li
Source:: Natural product research 2021 v.35 no.12 pp. 2090-2094
ISSN:: 1478-6427
Subject:: Escherichia coli; Kocuria kristinae; Staphylococcus aureus; Streptomyces; antibacterial properties; colorectal neoplasms; cytotoxicity; drugs; hepatoma; humans; metabolites; neoplasm cells; research; uterine cervical neoplasms
Abstract:: ... Antifungalmycin N2 (3-methyl-3,5-amino-4-vinyl-2-pyrone, C₆H₇O₂N) was a novel metabolite produced from Streptomyces sp. strain N2, and the present study aimed to evaluate its antibacterial and cytotoxic properties. By using Oxford cup method, the obtained results revealed that antifungalmycin N2 exhibited a significant antibacterial activity against the pathogenic bacteria such as Staphylococcus a ...
DOI:: 10.1080/14786419.2019.1652293
: https://doi.org/10.1080/14786419.2019.1652293

35. Diversity and Antimicrobial Activity of Endophytic Actinomycetes Isolated from Plant Roots in Thailand

Author:: N. Kuncharoen; W. Fukasawa; M. Mori; K. Shiomi; S. Tanasupawat
Source:: Microbiology 2019 v.88 no.4 pp. 479-488
ISSN:: 0026-2617
Subject:: Bacillus subtilis; Kocuria rhizophila; Micromonospora; Staphylococcus aureus; Streptomyces; antimicrobial properties; biodiversity; endophytes; metabolites; nucleotide sequences; phenotype; ribosomal RNA; roots; screening; Thailand
Abstract:: ... In this study, 37 endophytic actinomycetes were isolated from roots of 14 plant species obtained in Thailand, where biological diversity is known to be high. The isolates were identified as members of the genera Micromonospora (21 isolates), Streptomyces (14 isolates), Plantactinospora (1 isolate), and Polymorphospora (1 isolate) based on their phenotypic characteristics and the 16S rRNA gene sequ ...
DOI:: 10.1134/S0026261719040088
: https://doi.org/10.1134/S0026261719040088

36. Diversity of Culturable Thermophilic Actinobacteria in Hot Springs in Tengchong, China and Studies of their Biosynthetic Gene Profiles

Author:: Lan Liu; Nimaichand Salam; Jian-Yu Jiao; Hong-Chen Jiang; En-Min Zhou; Yi-Rui Yin; Hong Ming; Wen-Jun Li
Source:: Microbial ecology 2016 v.72 no.1 pp. 150-162
ISSN:: 0095-3628
Subject:: Acinetobacter baumannii; Actinomadura; Enterococcus faecalis; Escherichia coli; Microbispora; Micrococcus luteus; Micromonospora; Nocardiopsis; Nonomuraea; Promicromonospora; Pseudonocardia; Staphylococcus aureus; Streptomyces; Verrucosispora; anti-infective properties; antibiotics; habitats; hot springs; humans; industry; metabolites; multigene family; pathogens; phylogeny; polymerase chain reaction; ribosomal RNA; China
Abstract:: ... The class Actinobacteria has been a goldmine for the discovery of antibiotics and has attracted interest from both academics and industries. However, an absence of novel approaches during the last few decades has limited the discovery of new microbial natural products useful for industries. Scientists are now focusing on the ecological aspects of diverse environments including unexplored or undere ...
DOI:: 10.1007/s00248-016-0756-2
: https://doi.org/10.1007/s00248-016-0756-2

37. Endophytic Streptomyces in the traditional medicinal plant Arnica montana L.: secondary metabolites and biological activity

Author:: Tina Wardecki; Elke Brötz; Christian De Ford; Friederike D. von Loewenich; Yuriy Rebets; Bogdan Tokovenko; Andriy Luzhetskyy; Irmgard Merfort
Source:: Antonie van Leeuwenhoek 2015 v.108 no.2 pp. 391-402
ISSN:: 0003-6072
Subject:: Arnica montana; Candida parapsilosis; Fusarium verticillioides; Gram-positive bacteria; Staphylococcus aureus; Streptomyces; antibiotics; antifungal properties; cycloheximide; cytotoxicity; diketopiperazines; endophytes; medicinal plants; multigene family; mycorrhizal fungi; nutrients; pathogens; plant growth; secondary metabolites; sequence analysis; sesquiterpenoid lactones; soil; symbiosis
Abstract:: ... Arnica montana L. is a medical plant of the Asteraceae family and grows preferably on nutrient poor soils in mountainous environments. Such surroundings are known to make plants dependent on symbiosis with other organisms. Up to now only arbuscular mycorrhizal fungi were found to act as endophytic symbiosis partners for A. montana. Here we identified five Streptomyces strains, microorganisms also ...
DOI:: 10.1007/s10482-015-0492-5
: https://doi.org/10.1007/s10482-015-0492-5

38. Engineered biosynthesis of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities

Author:: Ah Reum Han; Pramod B. Shinde; Je Won Park; Jaeyong Cho; So Ra Lee; Yeon Hee Ban; Young Ji Yoo; Eun Ji Kim; Eunji Kim; Sung Ryeol Park; Byung-Gee Kim; Dong Gun Lee; Yeo Joon Yoon
Source:: Applied microbiology and biotechnology 2012 v.93 no.3 pp. 1147-1156
ISSN:: 0175-7598
Subject:: Enterococcus faecium; Staphylococcus aureus; Streptomyces venezuelae; antibacterial properties; biosynthesis; enzymes; erythromycin; mass spectrometry; multigene family; nuclear magnetic resonance spectroscopy; plasmids; structure-activity relationships; sugars
Abstract:: ... A 14-membered macrolide antibiotic narbomycin produced from Streptomyces venezuelae ATCC 15439 is composed of polyketide macrolactone ring and D-desosamine as a deoxysugar moiety, which acts as an important determinant of its antibacterial activity. In order to generate diverse glycosylated derivatives of narbomycin, expression plasmids carrying different deoxysugar biosynthetic gene cassettes and ...
DOI:: 10.1007/s00253-011-3592-9
PubMed:: 21959378
: https://doi.org/10.1007/s00253-011-3592-9

39. Enhanced Production of Antimicrobial Compounds by Three Salt-Tolerant Actinobacterial Strains Isolated from the Sundarbans in a Niche-Mimic Bioreactor

Author:: Sarkar, Sreyashi; Saha, Malay; Roy, Debashis; Jaisankar, Parasuraman; Das, Satadal; Gauri Roy, Lalita; Gachhui, Ratan; Sen, Tuhinadri; Mukherjee, Joydeep
Source:: Marine biotechnology 2008 v.10 no.5 pp. 518-526
ISSN:: 1436-2228
Subject:: Streptomyces; actinomycin D; aeration; anti-infective properties; bacteria; biofilm; bioreactors; environmental factors; habitats; littoral zone; metabolites; nucleotide sequences; ribosomal RNA; salt tolerance; submergence; Bay of Bengal
Abstract:: ... A novel reactor system, the rotating disk bioreactor (RDBR), was used to mimic the niche environmental conditions of three salt-tolerant estuarine actinobacteria isolated from the Sundarbans region off the Bay of Bengal, designated MS310 (99% similar in its 16S rRNA gene sequence to Streptomyces parvallus), MS3/20 and MS1/7. The RDBR, operated at a rotational speed of one revolution per day, 50% s ...
DOI:: 10.1007/s10126-008-9090-0
PubMed:: 18350335
: https://doi.org/10.1007/s10126-008-9090-0

40. Enzyme production, antibacterial and antifungal activities of actinobacteria isolated from Ficus deltoidea rhizosphere

Author:: ISRA JANATININGRUM; YULIN LESTARI
Source:: Biodiversitas 2022 v.23 no.4 pp. -
ISSN:: 2085-4722
Subject:: Bacillus subtilis; Candida albicans; Colletotrichum capsici; Escherichia coli; Ficus deltoidea; Fusarium oxysporum; Staphylococcus aureus; Streptomyces; amylases; antibacterial properties; antifungal properties; endo-1,4-beta-glucanase; enzyme activity; fungi; genes; proteinases; rhizosphere; secondary metabolites; soil
Abstract:: ... Janatiningrum I, Lestari Y. 2022. Enzyme production, antibacterial and antifungal activities of actinobacteria isolated from Ficus deltoidea rhizosphere. Biodiversitas 23: 1950-1957. Actinobacteria have long been known to have the ability to produce bioactive compounds and secondary metabolites. Actinobacteria from the rhizosphere of Ficus deltoidea Jack were expected to produce beneficial seconda ...
DOI:: 10.13057/biodiv/d230429
: https://doi.org/10.13057/biodiv/d230429

41. Evaluating the effect of various bacterial consortia on antibacterial activity of marine Streptomyces sp. AC117

Author:: Hanieh Shakeri Moghaddam; Bahar Shahnavaz; Ali Makhdoumi; Milad Iranshahy
Source:: Biocontrol science and technology 2021 v.31 no.11 pp. 1248-1266
ISSN:: 1360-0478
Subject:: Arthrobacter; Bacillus subtilis; Staphylococcus aureus; Streptomyces; agar; anthraquinones; antibacterial properties; biobased products; biological control; biosynthesis; coculture; drugs; fermentation; metabolites; Oman
Abstract:: ... The co-culture of microbial strains is able to activate silent biosynthetic gene clusters, leading to the production or improved production of natural compounds that do not occur under laboratory conditions. In this study, a new facultatively halophilic/psychrophilic Streptomyces sp. AC117 was initially isolated from the Sea of Oman. Then, three types of consortia were designed, using Streptomyces ...
DOI:: 10.1080/09583157.2021.1940865
: https://doi.org/10.1080/09583157.2021.1940865

42. Evaluation of Microbiological Quality of Vermicompost Prepared from Different Types of Organic Wastes using Eisenia fetida

Author:: Rachna Kapila; Geeta Verma; Aparajita Sen; Arti Nigam
Source:: Agricultural science digest 2021 v.41 no.3 pp. 445-449
ISSN:: 0976-0547
Subject:: Alternaria alternata; Aspergillus; Bacillus (bacteria); Eisenia fetida; Fusarium solani; Klebsiella; Micrococcus; Mucor hiemalis; Myrothecium verrucaria; Pseudomonas; Rhizopus; Staphylococcus aureus; Streptococcus; Streptomyces; Talaromyces purpurogenus; agricultural sciences; microbiological quality; nitrogen; organic wastes; phosphates; solubilization; urease; vermicomposting; vermicomposts; xylanases
Abstract:: ... Vermicomposting is the agricultural technique of conversion of organic wastes to a fertile product, which can result in better crop growth and production. However, even though earthworms are the main organisms participating in the process, the microbes associated with it also have an important role to play. These microbes degrade the waste products biochemically and are responsible of the conversi ...
DOI:: 10.18805/ag.D-5275
: https://doi.org/10.18805/ag.D-5275

43. Exploring Actinobacteria from North-Western Himalayas in Quest of Novel Pharmacophores

Author:: Brajeshwar Singh; Vironika; Hibbah Javed; Ankita; Upma Dutta; Gyanendra Kumar Rai
Source:: Indian journal of agricultural biochemistry 2021 v.34 no.2 pp. 205-208
ISSN:: 0974-4479
Subject:: Escherichia coli; Pseudomonas aeruginosa; Salmonella Typhimurium; Staphylococcus aureus; Streptomyces; antibiotics; biochemistry; humans; mortality; multiple drug resistance; pH; pharmacology; salt concentration; soil; temperature; Himalayan region
Abstract:: ... Actinomycetes are considered as the factories of antibiotics. They are chief soil microbes which also reside in aquatic habitats. They can tolerate high temperature, high salt concentration and high pH value. Most of existing antibiotics have been isolated from genus Streptomyces and Micromonaspora. In this study, 33 actinomycetes isolates were isolated from the soil samples collected from exclusi ...
DOI:: 10.5958/0974-4479.2021.00029.0
: https://doi.org/10.5958/0974-4479.2021.00029.0

44. Ficellomycin: an aziridine alkaloid antibiotic with potential therapeutic capacity

Author:: Xihong He; Meng Li; Shuting Song; Xiaonong Wu; Jing Zhang; Guoguo Wu; Rong Yue; Huanhuan Cui; Siqing Song; Congcong Ma; Fuping Lu; Huitu Zhang
Source:: Applied microbiology and biotechnology 2018 v.102 no.10 pp. 4345-4354
ISSN:: 0175-7598
Subject:: DNA; DNA fragmentation; DNA replication; Gram-positive bacteria; Staphylococcus aureus; Streptomyces; alkaloids; antibiotics; bioactive properties; biosynthesis; chromosomes; drugs; ethyleneimine; mechanism of action; multiple drug resistance; prototypes; stable isotopes
Abstract:: ... Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus, which displays high in vitro activity against Gram-positive bacteria including multidrug resistant strains of Staphylococcus aureus. Compared to currently available antibiotics, ficellomycin exhibits a unique mechanism of action—it impairs the semiconservative DNA replication by inducing the formation of deficient 34S DNA f ...
DOI:: 10.1007/s00253-018-8934-4
: https://doi.org/10.1007/s00253-018-8934-4

45. Functional gene-based discovery of phenazines from the actinobacteria associated with marine sponges in the South China Sea

Author:: Valliappan Karuppiah; Yingxin Li; Wei Sun; Guofang Feng; Zhiyong Li
Source:: Applied microbiology and biotechnology 2015 v.99 no.14 pp. 5939-5950
ISSN:: 0175-7598
Subject:: Actinoalloteichus; Bacillus mycoides; Escherichia coli; Kocuria; Micrococcus luteus; Micromonospora; Mycobacterium; Nocardiopsis; Porifera; Prauserella; Saccharopolyspora; Staphylococcus aureus; Streptomyces; antibacterial properties; bacteria; chemical analysis; culture media; electrospray ionization mass spectrometry; fermentation; gene expression; genes; nuclear magnetic resonance spectroscopy; phenazines; phylogeny; ribosomal RNA; screening; South China Sea
Abstract:: ... Phenazines represent a large group of nitrogen-containing heterocyclic compounds produced by the diverse group of bacteria including actinobacteria. In this study, a total of 197 actinobacterial strains were isolated from seven different marine sponge species in the South China Sea using five different culture media. Eighty-seven morphologically different actinobacterial strains were selected and ...
DOI:: 10.1007/s00253-015-6547-8
: https://doi.org/10.1007/s00253-015-6547-8

46. Genomic insights into the biosynthesis and physiology of the cyanobacterial neurotoxin 3-N-methyl-2,3-diaminopropanoic acid (BMAA)

Author:: Maria José Q. Mantas; Peter B. Nunn; Geoffrey A. Codd; Daniel Barker
Source:: Phytochemistry 2022 v.200 pp. 113198
ISSN:: 0031-9422
Subject:: Albizia julibrissin; Bacillariophyceae; Clostridium; Cyanobacteria; Lathyrus sativus; Pantoea agglomerans; Staphylococcus aureus; Streptomyces; active sites; biochemical pathways; bioinformatics; biosynthesis; cyanobacterial toxins; enzymes; genomics; methylation; multigene family; neurotoxins; peptides; photosynthesis; phylogeny; plant biochemistry; prokaryotic cells; sequence alignment; siderophores; substrate specificity
Abstract:: ... Cyanobacteria are an ancient clade of photosynthetic prokaryotes, present in many habitats throughout the world, including water resources. They can present health hazards to humans and animals due to the production of a wide range of toxins (cyanotoxins), including the diaminoacid neurotoxin, 3-N-methyl-2,3-diaminopropanoic acid (β-N-methylaminoalanine, BMAA). Knowledge of the biosynthetic pathwa ...
DOI:: 10.1016/j.phytochem.2022.113198
: https://doi.org/10.1016/j.phytochem.2022.113198

47. Genomics-Driven Discovery of Chlorinated Cyclic Hexapeptides Ulleungmycins A and B from a Streptomyces Species

Author:: Son Sangkeun; Hong Young-Soo; Jang Mina; Heo Kyung Taek; Lee Byeongsan; Jang Jun-Pil; Kim Jong-Won; Ryoo In-Ja; Kim Won-Gon; Ko Sung-Kyun; Kim Bo Yeon; Jang Jae-Hyuk; Ahn Jong Seog
Source:: Journal of natural products 2017 v.80 no.11 pp. 3025-3031
ISSN:: 1520-6025
Subject:: Staphylococcus aureus; Streptomyces; amino acids; antibacterial properties; antibiotic resistance; bacteria; culture media; derivatization; methicillin; multigene family; nuclear magnetic resonance spectroscopy; nucleotide sequences; peptides; spectral analysis
Abstract:: ... Analysis of the genome sequence of Streptomyces sp. KCB13F003 showed the presence of a cryptic gene cluster encoding flavin-dependent halogenase and nonribosomal peptide synthetase. Pleiotropic approaches using multiple culture media followed by LC-MS-guided isolation and spectroscopic analysis enabled the identification of two new chlorinated cyclic hexapeptides, ulleungmycins A and B (1 and 2). ...
DOI:: 10.1021/acs.jnatprod.7b00660
: https://doi.org/10.1021/acs.jnatprod.7b00660

48. Gephyyamycin and cysrabelomycin, two new angucyclinone derivatives from the Streptomyces sp. HN-A124

Author:: Biao Zhou; Yuan-Yuan Ji; Hao-Jian Zhang; Li Shen
Source:: Natural product research 2021 v.35 no.13 pp. 2117-2122
ISSN:: 1478-6427
Subject:: Candida albicans; Staphylococcus aureus; Streptomyces; X-ray diffraction; anthracenes; circular dichroism spectroscopy; cysteine; cytotoxicity; fermentation; humans; ovarian neoplasms; prostatic neoplasms; quantum mechanics; research; rice; China
Abstract:: ... Gephyyamycin (1) owned the rare 3,12a-epoxybenz[a]anthracene ring system, and cysrabelomycin (2) possessed an acetylated cysteine group, two new angucyclinone derivatives were isolated from the rice solid fermentation of the marine-derived Streptomyces sp. HN-A124, an actinobacterium isolated from the marine sediments collected from Hainan Province, China. Their structures were elucidated on the b ...
DOI:: 10.1080/14786419.2019.1660336
: https://doi.org/10.1080/14786419.2019.1660336

49. Gram-positive aerobic and microaerophilic microorganisms isolated from pathological processes and lesions of horses

Author:: J. Bzdil; O. Holy; D. Chmelar
Source:: Veterinární medicína v.62 no.1 pp. 1-9
ISSN:: 0375-8427
Subject:: Aerococcus viridans; Arcanobacterium pyogenes; Bacillus (bacteria); Corynebacterium; Dermatophilus congolensis; Enterococcus; Lysinibacillus; Nocardiopsis alba; Staphylococcus aureus; Streptococcus; Streptomyces; antibiotic resistance; clavulanic acid; digestive tract; florfenicol; lymphatic system; milk; musculoskeletal system; phenotype; respiratory system; urinary tract
Abstract:: ... The aim of this study was to characterise the genera and species of Gram-positive aerobic and microaerophilic microorganisms isolated from pathological processes and lesions in horses. In the period 2009–2014, 449 clinical samples from horses were examined. Of these, 229 (51%) were collected from the respiratory tract, 121 (26.9%) from the skin, 40 (8.9%) from the gastrointestinal tract, 40 (8.9%) ...
DOI:: 10.17221/107/2016-vetmed
: https://doi.org/10.17221/107/2016-vetmed

50. Green biosynthesis of silver nanoparticles produced from marine Streptomyces sp. Al-Dhabi-89 and their potential applications against wound infection and drug resistant clinical pathogens

Author:: Naif Abdullah Al-Dhabi; Abdul-Kareem Mohammed Ghilan; Mariadhas Valan Arasu; Veeramuthu Duraipandiyan
Source:: Journal of photochemistry and photobiology 2018 v.189 pp. 176-184
ISSN:: 1011-1344
Subject:: Acinetobacter baumannii; Enterococcus faecium; Escherichia coli; Fourier transform infrared spectroscopy; Gram-negative bacteria; Klebsiella pneumoniae; Proteus mirabilis; Pseudomonas aeruginosa; Staphylococcus aureus; Streptomyces; X-ray diffraction; antimicrobial properties; biosynthesis; energy-dispersive X-ray analysis; minimum inhibitory concentration; multiple drug resistance; nanoparticles; nanosilver; pathogens; ribosomal RNA; scanning electron microscopy; secondary metabolites; silver; surface plasmon resonance; transmission electron microscopy; ultraviolet-visible spectroscopy; value added; Persian Gulf
Abstract:: ... Green biosynthesis of nanoparticles yielded from the extracellular metabolites of marine derived actinomycetes is covering enormous attention due to their superior applications and broad spectrum of bioactive secondary metabolites. The present study aimed to explore the characterization of novel bioactive Streptomyces sp. Al-Dhabi-89 derived from the Arabian Gulf region of Dammam was authenticated ...
DOI:: 10.1016/j.jphotobiol.2018.09.012
: https://doi.org/10.1016/j.jphotobiol.2018.09.012

51. Gwanakosides A and B, 6-Deoxy-α-l-talopyranose-Bearing Aromatic Metabolites from a Streptomyces sp. and Coculture with Pandoraea sp.

Author:: Thanh-Hau Huynh; Jayho Lee; Dong Hyun Moon; Thanh Quang Nguyen; Sangkeun Son; Sunghoon Hwang; Young Eun Du; Jinsheng Cui; Jae-Hyuk Jang; Sang-Jip Nam; Jongheon Shin; Jichan Jang; Sang Kook Lee; Ki-Bong Oh; Dong-Chan Oh
Source:: Journal of natural products 2021 v.85 no.1 pp. 83-90
ISSN:: 1520-6025
Subject:: Mycobacterium tuberculosis; Pandoraea; Staphylococcus aureus; Streptomyces; chlorine; chromatography; coculture; derivatization; glycosides; humans; metabolites; naphthalene; neoplasm cells; spectral analysis
Abstract:: ... Single-strain cultivation of a mountain soil-derived Streptomyces sp. GA02 and its coculture with Pandoraea sp. GA02N produced two aromatic products, gwanakosides A and B (1 and 2, respectively). Their spectroscopic analysis revealed that 1 is a new dichlorinated naphthalene glycoside and 2 is a pentacyclic aromatic glycoside. The assignment of the two chlorine atoms in 1 was confirmed by the anal ...
DOI:: 10.1021/acs.jnatprod.1c00703
: https://doi.org/10.1021/acs.jnatprod.1c00703

52. Halophilic and halotolerant actinomycetes from a marine saltern of Goa, India producing anti-bacterial metabolites

Author:: Shuvankar Ballav; Savita Kerkar; Sabu Thomas; Nimmy Augustine
Source:: Journal of bioscience and bioengineering 2015 v.119 no.3 pp. 323-330
ISSN:: 1389-1723
Subject:: Kocuria; Micromonospora; Nocardiopsis; Staphylococcus aureus; Streptomyces; Vibrio cholerae; agar; antibacterial properties; antibiotics; casein; ecosystems; estuaries; halophiles; metabolites; pathogens; salinity; salt tolerance; sediments; solvents; starch; India
Abstract:: ... Marine salterns are estuarine ecosystems in Goa, receiving inputs from riverine and marine waters. The Salinity fluctuates between 0 and 300 psu which makes it a conducive niche for salt tolerant and salt loving Actinomycetales. Halotolerant and halophilic Actinomycetales producing anti-bacterial metabolites were studied from crystallizer pond sediments of Ribandar saltern, Goa. Three media viz. S ...
DOI:: 10.1016/j.jbiosc.2014.08.017
: https://doi.org/10.1016/j.jbiosc.2014.08.017

53. Hygrocin C from marine-derived Streptomyces sp. SCSGAA 0027 inhibits biofilm formation in Bacillus amyloliquefaciens SCSGAB0082 isolated from South China Sea gorgonian

Author:: Jie Wang; Xu-Hua Nong; Muhammad Amin; Shu-Hua Qi
Source:: Applied microbiology and biotechnology 2018 v.102 no.3 pp. 1417-1427
ISSN:: 0175-7598
Subject:: Bacillus amyloliquefaciens; Staphylococcus aureus; Streptomyces; arginine; biofilm; cell movement; chemotaxis; genes; histidine; hydrophobicity; lipopeptides; minimum inhibitory concentration; transcriptomics; South China Sea
Abstract:: ... Several ansamycins have been reported to inhibit bacterial biofilm formation and accelerate the eradication of developed biofilms, but little is known about the effect of hygrocin C, an ansamycin, on bacterial biofilm formation. Here, hygrocin C was isolated from the marine-derived Streptomyces sp. SCSGAA 0027 and reported for the first time to be capable of inhibiting the biofilm formation of Sta ...
DOI:: 10.1007/s00253-017-8672-z
: https://doi.org/10.1007/s00253-017-8672-z

54. Identification and Characterization of the Anti-Methicillin-Resistant Staphylococcus aureus WAP-8294A2 Biosynthetic Gene Cluster from Lysobacter enzymogenes OH11

Author:: Wei Zhang; Yaoyao Li; Guoliang Qian; Yan Wang; Haotong Chen; Yue-Zhong Li; Fengquan Liu; Yuemao Shen; Liangcheng Du
Source:: Antimicrobial agents and chemotherapy 2011 v.55 no.12 pp. 5581-5589
ISSN:: 0066-4804
Subject:: Lysobacter enzymogenes; Staphylococcus aureus; Streptomyces; antibacterial properties; antibiotic resistance; antifungal agents; bacteria; biological control agents; bioprocess engineering; biosynthesis; chemical structure; clinical trials; fungi; gene targeting; ligases; mass spectrometry; metabolites; methicillin; multigene family; nuclear magnetic resonance spectroscopy; open reading frames; peptides; polyketides; soil
Abstract:: ... Lysobactor enzymogenes strain OH11 is an emerging biological control agent of fungal and bacterial diseases. We recently completed its genome sequence and found it contains a large number of gene clusters putatively responsible for the biosynthesis of nonribosomal peptides and polyketides, including the previously identified antifungal dihydromaltophilin (HSAF). One of the gene clusters contains t ...
DOI:: 10.1128/AAC.05370-11
PubMed:: 21930890
PubMed Central:: PMC3232812
: https://doi.org/10.1128/AAC.05370-11

55. Identification and characterization of the ficellomycin biosynthesis gene cluster from Streptomyces ficellus

Author:: Yang Liu; Meng Li; Huiyan Mu; Shuting Song; Ying Zhang; Kun Chen; Xihong He; Haikuan Wang; Yujie Dai; Fuping Lu; Zhongli Yan; Huitu Zhang
Source:: Applied microbiology and biotechnology 2017 v.101 no.20 pp. 7589-7602
ISSN:: 0175-7598
Subject:: DNA; DNA replication; Penicillium oxalicum; Staphylococcus aureus; Streptomyces; antibiotics; biosynthesis; crosslinking; hexane; multigene family; open reading frames; sulfate adenylyltransferase
Abstract:: ... Ficellomycin is a peptide-like antibiotic which exhibits potent in vitro activity against Penicillium oxalicum and Staphylococcus aureus, even against strains resistant to most clinically used antibiotics. The gene cluster responsible for ficellomycin biosynthesis was cloned from Streptomyces ficellus and sequenced. It was found to contain 26 ORFs and is located within 30 kb of contiguous DNA. Tar ...
DOI:: 10.1007/s00253-017-8465-4
: https://doi.org/10.1007/s00253-017-8465-4

56. Identification of Elaiophylin Skeletal Variants from the Indonesian Streptomyces sp. ICBB 9297

Author:: Sheng Yan; Lam Phillip W.; Shahab Salmah; Santosa Dwi Andreas; Proteau Philip J.; Zabriskie T. Mark; Mahmud Taifo
Source:: Journal of natural products 2015 v.78 no.11 pp. 2768-2775
ISSN:: 1520-6025
Subject:: Mycobacterium smegmatis; Staphylococcus aureus; Streptomyces; active sites; amino acids; antibacterial properties; bioinformatics; macrolides; methylmalonyl-coenzyme A; polyketide synthases; soil bacteria
Abstract:: ... Four new elaiophylin macrolides (1–4), together with five known elaiophylins (5–9), have been isolated from cultures of the Indonesian soil bacterium Streptomyces sp. ICBB 9297. The new compounds have macrocyclic skeletons distinct from those of the known dimeric elaiophylins in that one or both of the polyketide chains contain(s) an additional pendant methyl group. Further investigations revealed ...
DOI:: 10.1021/acs.jnatprod.5b00752
: https://doi.org/10.1021/acs.jnatprod.5b00752

57. In Situ Cultured Bacterial Diversity from Iron Curtain Cave, Chilliwack, British Columbia, Canada

Author:: Soumya Ghosh; Elise Paine; Rob Wall; Gabrielle Kam; Tanna Lauriente; Pet-Chompoo Sa-ngarmangkang; Derrick Horne; Naowarat Cheeptham
Source:: Diversity 2017 v.9 no.3 pp. -
ISSN:: 1424-2818
Subject:: Arthrobacter; Bacteroidetes; Brevundimonas; Escherichia coli; Pseudomonas; Sporosarcina; Staphylococcus aureus; Stenotrophomonas; Streptomyces; anti-infective agents; antimicrobial properties; bacteria; habitats; multiple drug resistance; ribosomal RNA; sequence analysis; British Columbia
Abstract:: ... The culturable bacterial diversity from Iron Curtain Cave, Chilliwack, British Columbia, Canada was examined. Sixty five bacterial isolates were successfully cultivated, purified, and identified based on 16S rRNA gene sequencing. Four distinguishable phyla, i.e., Actinobacteria (44.61%), Proteobacteria (27.69%), Firmicutes (20%) and Bacteroidetes (7.69%) were identified. Arthrobacter (21.53%) was ...
DOI:: 10.3390/d9030036
: https://doi.org/10.3390/d9030036

58. In vitro activity of 5-(2,4-dimethylbenzyl) pyrrolidin-2-one extracted from marine Streptomyces VITSVK5 spp. against fungal and bacterial human pathogens

Author:: Kumar Saurav; K. Kannabiran
Source:: Revista iberoamericana de micología 2012 v.29 no.1 pp. 29-33
ISSN:: 1130-1406
Subject:: Aspergillus niger; Bacillus subtilis; Escherichia coli; Fourier transform infrared spectroscopy; Klebsiella pneumoniae; Staphylococcus aureus; Streptomyces; animal pathogens; antibacterial properties; bacteria; coasts; drugs; fungi; gel chromatography; human diseases; nuclear magnetic resonance spectroscopy; screening; sediments; spectral analysis; traditional medicine; Bay of Bengal; India
Abstract:: ... BACKGROUND: Pharmacological screening and usage of natural products for the treatment of human diseases has had a long history from traditional medicine to modern drugs. The majority of modern drugs are reported to be mostly from natural products. OBJECTIVE: The aim of the present study was to evaluate the inhibitory activity of 5-(2,4-dimethylbenzyl) pyrrolidin-2-one (DMBPO) extracted from marine ...
DOI:: 10.1016/j.riam.2011.06.008
: https://doi.org/10.1016/j.riam.2011.06.008

59. Inhibition of Staphylococcus aureus by antimicrobial biofilms formed by competitive exclusion microorganisms on stainless steel

Author:: Hyeri Son; Sunhyung Park; Larry R. Beuchat; Hoikyung Kim; Jee-Hoon Ryu
Source:: International journal of food microbiology 2016 v.238 pp. 165-171
ISSN:: 0168-1605
Subject:: Pseudomonas azotoformans; Staphylococcus aureus; Streptomyces; antibacterial properties; biofilm; competitive exclusion; foods; microbiological quality; microorganisms; relative humidity; soil; stainless steel
Abstract:: ... The goal of this study was to develop a desiccation resistant antimicrobial surface using biofilm of competitive exclusion (CE) microorganism inhibitory to Staphylococcus aureus. We isolated 161 microorganisms from soils, foods, and food-contact surfaces that are inhibitory to S. aureus. Among them, three CE microorganisms (Streptomyces spororaveus strain Gaeunsan-18, Bacillus safensis strain Cham ...
DOI:: 10.1016/j.ijfoodmicro.2016.09.007
: https://doi.org/10.1016/j.ijfoodmicro.2016.09.007

60. Inhibition of bacterial RNA polymerases. Peptide metabolites from the cultures of Streptomyces sp

Author:: Miao, S.; Anstee, M.R.; LaMarco, K.; Matthew, J.; Huang, L.H.T.; Brasseur, M.M.
Source:: Journal of natural products 1997 v.60 no.8 pp. 858-861
ISSN:: 0163-3864
Subject:: Streptomyces; soil bacteria; fermentation; chemical composition; cyclic peptides; spectral analysis; chemical structure; antibiotics; DNA-directed RNA polymerase; enzyme inhibitors; Staphylococcus aureus; Escherichia coli; culture filtrates; Georgia
DOI:: 10.1021/np960709c
: https://doi.org/10.1021/np960709c

61. Intra‐clade metabolomic profiling of MAR4 Streptomyces from the Macaronesia Atlantic region reveals a source of anti‐biofilm metabolites

Author:: Anelize Bauermeister; Florbela Pereira; Inês R. Grilo; Camila C. Godinho; Marisa Paulino; Vanessa Almeida; Leonardo Gobbo‐Neto; Alejandra Prieto‐Davó; Rita G. Sobral; Norberto P. Lopes; Susana P. Gaudêncio
Source:: Environmental microbiology 2019 v.21 no.3 pp. 1099-1112
ISSN:: 1462-2912
Subject:: Marinobacter hydrocarbonoclasticus; Staphylococcus aureus; Streptomyces; anti-infective agents; antibiotic resistance; antimicrobial properties; bacterial communities; biofilm; chemical derivatives; ecoregions; isoprenoids; liquid chromatography; metabolites; metabolomics; multivariate analysis; phylogeny; principal component analysis; resistance mechanisms; tandem mass spectrometry
Abstract:: ... The search for new and effective strategies to reduce bacterial biofilm formation is of utmost importance as bacterial resistance to antibiotics continues to emerge. The use of anti‐biofilm agents that can disrupt recalcitrant bacterial communities can be an advantageous alternative to antimicrobials, as their use does not lead to the development of resistance mechanisms. Six MAR4 Streptomyces str ...
DOI:: 10.1111/1462-2920.14529
: https://doi.org/10.1111/1462-2920.14529

62. Isolation and Structural Determination of Makinolide B from Streptomyces sp. MK-19

Author:: Michitaka HIDAKI; Mitsuru YOSHIDA; Naoto OGAWA; Shinya KODANI
Source:: Bioscience, biotechnology, and biochemistry 2013 v.77 no.9 pp. 1964-1966
ISSN:: 1347-6947
Subject:: Staphylococcus aureus; Streptomyces; antibacterial properties; biotechnology; disk diffusion antimicrobial test; macrolides
Abstract:: ... A new 16-membered macrolide named makinolide B (1) was isolated from Streptomyces sp. MK-19. The structure of makinolide B (1) was determined on the basis of 2D NMR experiments involving DQF-COSY, TOCSY, HSQC, and HMBC methods. Application of the paper disk diffusion method to makinolide B (1) showed weak antibacterial activity against Staphylococcus aureus at the dose of 100 µg/disk. ...
DOI:: 10.1271/bbb.130204
: https://doi.org/10.1271/bbb.130204

63. Isolation and characterization of anti-methicillinresistant Staphylococcus aureus/vancomycinresistant Enterococcus compound from Streptomyces bungoensis MJM 2077

Author:: Jinhua Cheng; Ying-Yu Jin; Seung Hwan Yang; Joo-Won Suh
Source:: Han'guk Ŭngyong Saengmyŏng Hwahakhoe chi = 2013 v.56 no.1 pp. 107-111
ISSN:: 1738-2203
Subject:: Enterococcus; Staphylococcus aureus; Streptomyces; active ingredients; mass spectrometry; nuclear magnetic resonance spectroscopy; nucleotide sequences; ribosomal DNA
Abstract:: ... Strain MJM2077 was selected for its strong anti-Methicillin-resistant Staphylococcus aureus/Vancomycin-resistant Enterococcus activity and designated as Streptomyces bungoensis MJM2077 based on the analysis of the 16S rDNA sequence. The active compound, which was very stable under acidic conditions, was purified and identified as echinomycin by NMR and mass spectrometry. This is the first report o ...
DOI:: 10.1007/s13765-012-2227-x
: https://doi.org/10.1007/s13765-012-2227-x

64. Isolation and characterization of wastewater sand filter actinomycetes

Author:: Bensultana, Asmaa; Ouhdouch, Yedir; Hassani, Lahcen; Mezrioui, Nour-Eddine; Rafouk, Leila
Source:: World journal of microbiology & biotechnology 2010 v.26 no.3 pp. 481-487
ISSN:: 0959-3993
Subject:: Candida albicans; Salmonella; Staphylococcus aureus; Streptomyces; antimicrobial properties; pathogens; sand; wastewater; yeasts
Abstract:: ... One hundred twenty-two different actinomycete strains were isolated from sample collected from several depths of the Marrakech wastewater infiltration-percolation system. To evaluate the antimicrobial effect of the different actinomycetes recovered, eleven wastewater-associated micro-organisms known as human potential pathogens were used. Results showed that 44 isolates had an in vitro inhibitory ...
DOI:: 10.1007/s11274-009-0194-0
: https://doi.org/10.1007/s11274-009-0194-0

65. Isolation and diversity of natural product biosynthetic genes of cultivable bacteria associated with marine sponge Mycale sp. from the coast of Fujian, China

Author:: Pei Su; De-Xiang Wang; Shao-Xiong Ding; Jing Zhao
Source:: Canadian journal of microbiology 2014 v.60 no.4 pp. 217-225
ISSN:: 1480-3275
Subject:: Bacillus subtilis; Burkholderia gladioli; Cyanobacteria; Gram-positive bacteria; Mycale; Nocardiopsis; Rhodococcus opacus; Staphylococcus aureus; Streptomyces; Vibrio; alpha-Proteobacteria; amino acid composition; amino acid sequences; antibacterial properties; bacterial communities; coasts; genes; phylogeny; polyketide synthases; ribosomal RNA; screening; China
Abstract:: ... The marine sponge Mycale sp., a potential source of natural bioactive products, is widely distributed along the coast of Fujian, China. The cultivable bacterial community associated with Mycale sp., the antibacterial activities, and the PKS (polyketide synthase) and NRPS (nonribosomal peptide synthetase) gene diversity of these bacteria were investigated. Phylogenetic analysis of the 16S rRNA gene ...
DOI:: 10.1139/cjm-2013-0785
: https://doi.org/10.1139/cjm-2013-0785

66. Isolation and partial purification of erythromycin from alkaliphilic Streptomyces werraensis isolated from Rajkot, India

Author:: Gaurav V. Sanghvi; Dipak Ghevariya; Subhash Gosai; Riddhi Langa; Niketa Dhaduk; Prashant D. Kunjadia; Devendra J. Vaishnav; Gaurav S. Dave
Source:: Biotechnology reports 2014 v.1-2 pp. 2-7
ISSN:: 2215-017X
Subject:: Bacillus subtilis; Escherichia coli; Fourier transform infrared spectroscopy; Staphylococcus aureus; Streptomyces werraensis; alkanes; chloroform; erythromycin; high performance liquid chromatography; methanol; minimum inhibitory concentration; pH; phylogeny; sodium chloride; soil bacteria; sucrose; yeast extract; India
Abstract:: ... An alkaliphilic actinomycete, BCI-1, was isolated from soil samples collected from Saurashtra University campus, Gujarat. Isolated strain was identified as Streptomyces werraensis based on morphological, biochemical and phylogenetic analysis. Maximum antibiotic production was obtained in media containing sucrose 2%, Yeast extract 1.5%, and NaCl 2.5% at pH 9.0 for 7 days at 30 °C. Maximum inhibitor ...
DOI:: 10.1016/j.btre.2014.05.003
PubMed:: 28435796
PubMed Central:: PMC5381693
: https://doi.org/10.1016/j.btre.2014.05.003

67. Ligiamycins A and B, Decalin-Amino-Maleimides from the Co-Culture of Streptomyces sp. and Achromobacter sp. Isolated from the Marine Wharf Roach, Ligia exotica

Author:: Hyung-Ju Lim; Joon Soo An; Eun Seo Bae; Eunji Cho; Sunghoon Hwang; Sang-Jip Nam; Ki-Bong Oh; Sang Kook Lee; Dong-Chan Oh
Source:: Marine drugs 2022 v.20 no.2 pp. -
ISSN:: 1660-3397
Subject:: Achromobacter; Ligia; Salmonella enterica; Staphylococcus aureus; Streptomyces; coasts; coculture; colorectal neoplasms; cytotoxicity; digestive system; humans; littoral zone; metabolites; nitrogen; nuclear magnetic resonance spectroscopy; quantum mechanics; spectral analysis; Korean Peninsula
Abstract:: ... Streptomyces sp. GET02.ST and Achromobacter sp. GET02.AC were isolated together from the gut of the wharf roach, Ligia exotica, inhabiting the intertidal zone of the west coast of Korea. The co-cultivation of these two strains significantly induced the production of two new metabolites, ligiamycins A (1) and B (2), which were barely detected in the single culture of Streptomyces sp. GET02.ST. The ...
DOI:: 10.3390/md20020083
: https://doi.org/10.3390/md20020083

68. MS Analysis and Molecular Characterization of Botrytis cinerea Protease Prot-2. Use in Bioactive Peptides Production

Author:: Ferid Abidi; Nayssene Aissaoui; Jean-Charles Gaudin; Jean-Marc Chobert; Thomas Haertlé; Mohamed Nejib Marzouki
Source:: Applied biochemistry and biotechnology 2013 v.170 no.2 pp. 231-247
ISSN:: 0273-2289
Subject:: Botrytis cinerea; Glomerella graminicola; Metarhizium anisopliae; Scomber; Streptomyces; amino acid sequences; amino acids; bioactive properties; chymotrypsin; complementary DNA; hydrolysis; mackerel; mass spectrometry; open reading frames; peptides; plant pathogenic bacteria; plant pathogenic fungi; protein hydrolysates; proteolysis; sequence alignment; sequence homology; trypsin
Abstract:: ... Prot-2 protease previously purified to homogeneity from Botrytis cinerea showed potentiality to be used in detergency and for production of bioactive peptides. To extend the characterization of Prot-2 protease, antifungal and antibacterial assays were performed in vitro using protein hydrolysates prepared from muscle of mackerel (Scomber scomborus) treated with this enzyme. The most active hydroly ...
DOI:: 10.1007/s12010-013-0186-2
PubMed:: 23494220
: https://doi.org/10.1007/s12010-013-0186-2

69. Marmycins A and B, Cytotoxic Pentacyclic C-Glycosides from a Marine Sediment-Derived Actinomycete Related to the Genus Streptomyces

Author:: Martin, G.D.A.; Tan, L.T.; Jensen, P.R.; Dimayuga, R.E.; Fairchild, C.R.; Raventos-Suarez, C.; Fenical, W.
Source:: Journal of natural products 2007 v.70 no.9 pp. 1406-1409
ISSN:: 0163-3864
Subject:: sediments; humans; quinones; cytotoxicity; cultured cells; spectral analysis; Streptomyces; glycosides; chemical structure; stereochemistry; anticarcinogenic activity; Mexico
DOI:: 10.1021/np060621r
PubMed:: 17844998
: https://doi.org/10.1021/np060621r

70. Meliponamycins: Antimicrobials from Stingless Bee-Associated Streptomyces sp.

Author:: Carla Menegatti; Vitor Bruno Lourenzon; Diego Rodríguez-Hernández; Weilan Gomes da Paixão Melo; Leonardo Luiz Gomes Ferreira; Adriano Defini Andricopulo; Fabio Santos do Nascimento; Mônica Tallarico Pupo
Source:: Journal of natural products 2020 v.83 no.3 pp. 610-616
ISSN:: 1520-6025
Subject:: Leishmania infantum; Melipona scutellaris; Paenibacillus larvae; Staphylococcus aureus; Streptomyces; amino acids; anti-infective agents; entomopathogens; microorganisms; nuclear magnetic resonance spectroscopy; pollinators; social insects; stingless bees
Abstract:: ... Social insects establish complex interactions with microorganisms, some of which play defensive roles in colony protection. The important role of pollinators such as the stingless bee Melipona scutellaris in nature encouraged us to pursue efforts to study its associated microbiota. Here we describe the discovery of two novel cyclic hexadepsipeptides, meliponamycin A (1) and meliponamycin B (2), fr ...
DOI:: 10.1021/acs.jnatprod.9b01011
: https://doi.org/10.1021/acs.jnatprod.9b01011

71. Meroindenon and Merochlorins E and F, Antibacterial Meroterpenoids from a Marine-Derived Sediment Bacterium of the Genus Streptomyces

Author:: Min-Ji Ryu; Sunghoon Hwang; Sojeong Kim; Inho Yang; Dong-Chan Oh; Sang-Jip Nam; William Fenical
Source:: Organic letters 2019 v.21 no.15 pp. 5779-5783
ISSN:: 1523-7052
Subject:: Bacillus subtilis; Staphylococcus aureus; Streptomyces; antibacterial properties; bacteria; chemical reactions; chemical structure; meroterpenoids; minimum inhibitory concentration; nuclear magnetic resonance spectroscopy; sediments; spectral analysis
Abstract:: ... Meroterpenoids, meroindenon (1) and merochlorins E (2) and F (3), were isolated from a marine-derived bacterium belonging to the genus Streptomyces. Their chemical structures were established using extensive analysis of MS, UV, ECD, and NMR spectroscopic data. Compounds 1–3 possess a tetrahydroxynaphthalene core and a C₁₅-isoprene unit. Compounds 2 and 3 exhibited strong antibacterial activities a ...
DOI:: 10.1021/acs.orglett.9b01440
: https://doi.org/10.1021/acs.orglett.9b01440

72. Metabolic Engineering of Nocardia sp. CS682 for Enhanced Production of Nargenicin A1

Author:: Sushila Maharjan; Dinesh Koju; Hei Chan Lee; Jin Cheol Yoo; Jae Kyung Sohng
Source:: Applied biochemistry and biotechnology 2012 v.166 no.3 pp. 805-817
ISSN:: 0273-2289
Subject:: Nocardia; Staphylococcus aureus; Streptomyces; acetyl-CoA carboxylase; antibacterial properties; electroporation; genes; methionine adenosyltransferase; recombinant DNA; reverse transcriptase polymerase chain reaction; secondary metabolites; transcription (genetics); transcription factors; transcriptional activation; South Korea
Abstract:: ... A number of secondary metabolites having therapeutic importance have been reported from the genus Nocardia. One of the polyketide antibiotic compounds isolated from Nocardia is nargenicin A1. Recently, nargenicin A1 has been isolated from Nocardia sp. CS682, a new Nocardia strain isolated from soil in Jeonnam, South Korea. It possesses strong antibacterial activity against methicillin-resistant St ...
DOI:: 10.1007/s12010-011-9470-1
PubMed:: 22161261
: https://doi.org/10.1007/s12010-011-9470-1

73. Methylsulfomycin I, a new cyclic peptide antibiotic from a streptomyces sp. HIL Y-9420704

Author:: Vijaya Kumar, E.K.S.; Kenia, J.; Mukhopadhyay, T.; Nadkarni, S.R.
Source:: Journal of natural products 1999 v.62 no.11 pp. 1562-1564
ISSN:: 0163-3864
Subject:: chemical composition; Staphylococcus aureus; cyclic peptides; soil bacteria; drug resistance; methicillin; Gram-positive bacteria; spectral analysis; Streptomyces; chemical structure; antibacterial properties; Greece
DOI:: 10.1021/np990088y
PubMed:: 10579874
: https://doi.org/10.1021/np990088y

74. Molecular Genotyping and Antimicrobial Activities of Secondary Metabolites from Streptomyces sp: Taxonomy, Extraction and Purification

Author:: Pramod P. Desai; C. Prabhurajeshwar; R. Kelmani Chandrakant
Source:: Journal of Biologically Active Products from Nature 2016 v.6 no.4 pp. 282-298
ISSN:: 2231-1874
Subject:: Escherichia coli; Fourier transform infrared spectroscopy; Klebsiella pneumoniae; Pseudomonas aeruginosa; Staphylococcus aureus; Streptomyces; active ingredients; antibacterial properties; chromatography; ethyl acetate; genotyping; mass spectrometry; multiple drug resistance; nucleotide sequences; pH; pathogens; phenols; ribosomal DNA; screening; secondary metabolites; sequence analysis; soil; taxonomy; India
Abstract:: ... A total of 57 native actinomycetes cultures with distinct characteristics were isolated from a field soil sample collected from Gulbarga region, Karnataka state, India. Out of these isolates, 4 potent isolates showed antibacterial activity against clinical pathogens in primary screening process by cross streak technique. The secondary metabolites produced by one of the strain Streptomyces sp. GUT ...
DOI:: 10.1080/22311866.2016.1259587
: https://doi.org/10.1080/22311866.2016.1259587

75. Molecular Identification of Streptomyces producing antibiotics and their antimicrobial activities

Author:: Latifa A. Al_husnan; Muneera D.F. Alkahtani
Source:: Annals of agricultural science 2016 v.61 no.2 pp. 251-255
ISSN:: 0570-1783
Subject:: Aspergillus niger; Bacillus cereus; Candida albicans; Pseudomonas aeruginosa; Staphylococcus aureus; Streptomyces; agricultural sciences; antibacterial properties; antibiotics; antifungal properties; biological control agents; color; gene amplification; genes; microorganisms; mycelium; polymerase chain reaction; rhizosphere; ribosomal DNA; soil; spores; starch; Saudi Arabia
Abstract:: ... Five strains of Streptomyces, namely S, N, W, E and C (designations should be mentioned in detail here) isolated from the rhizosphere soil cultivated with palm Alajua (date, pressed dates), AlMedina city, Saudi Arabia, were induced to produce antibiotics. Antimicrobial activities were determined on solid medium supplemented with starch. The detection was based on the formation of transparent zones ...
DOI:: 10.1016/j.aoas.2016.06.002
: https://doi.org/10.1016/j.aoas.2016.06.002

76. Multifarious Pharmacological Applications of Green Routed Eco-Friendly Iron Nanoparticles Synthesized by Streptomyces Sp. (SRT12)

Author:: Srinath Rajeswaran; Somasundaram Somasundaram Thirugnanasambandan; Naresh Kumar Dewangan; Rajesh Kannan Moorthy; Saravanan Kandasamy; Ravikumar Vilwanathan
Source:: Biological trace element research 2020 v.194 no.1 pp. 273-283
ISSN:: 0163-4984
Subject:: 4',6-diamidino-2-phenylindole; Bacillus subtilis; Escherichia coli; Fourier transform infrared spectroscopy; Klebsiella pneumoniae; Shigella flexneri; Staphylococcus aureus; Streptomyces; X-ray diffraction; antioxidant activity; ascorbic acid; atomic force microscopy; biosynthesis; cell lines; coprecipitation; cytotoxicity; energy-dispersive X-ray analysis; iron; nanoparticles; pathogens; scanning electron microscopy; staining; ultraviolet-visible spectroscopy; zeta potential
Abstract:: ... A simple, eco-friendly, green routine co-precipitation method was experimented to synthesize iron nanoparticles (Fe-NPs) using the cell-free supernatant of actinobacteria. The biosynthesized nanoparticles were characterized by UV-Vis spectroscopy, X-ray diffractometer (XRD), energy-dispersive X-ray (EDX), scanning electron microscopy (SEM), atomic force microscopy (AFM), zeta potential analyser an ...
DOI:: 10.1007/s12011-019-01777-5
: https://doi.org/10.1007/s12011-019-01777-5

77. Mutasynthesis of Antibacterial Halogenated Actinomycin Analogues

Author:: Ziwei Yao; Changli Sun; Yuhui Xia; Fang Wang; Liwu Fu; Junying Ma; Qinglian Li; Jianhua Ju
Source:: Journal of natural products 2021 v.84 no.8 pp. 2217-2225
ISSN:: 1520-6025
Subject:: Candida albicans; Enterococcus faecium; Staphylococcus aureus; Streptomyces; antibiotic resistance; biosynthesis; cytotoxicity; mutants
Abstract:: ... Through precursor-directed biosynthesis, feeding halogenated (F-, Cl-, Br-, I-) or methoxy-substituted 4-methyl-3-hydroxyanthranilic acid (4-MHA) analogues to the acnGHLM-deleted mutant strain of Streptomyces costaricanus SCSIO ZS0073 led to the production of ten new actinomycin analogues (4–13). Several of the actinomycin congeners displayed impressive antimicrobial activities, with MIC values sp ...
DOI:: 10.1021/acs.jnatprod.1c00294
: https://doi.org/10.1021/acs.jnatprod.1c00294

78. New Napyradiomycin Analogues from Streptomyces sp. Strain CA-271078

Author:: Daniel Carretero-Molina; Francisco Javier Ortiz-López; Jesús Martín; Daniel Oves-Costales; Caridad Díaz; Mercedes de la Cruz; Bastien Cautain; Francisca Vicente; Olga Genilloud; Fernando Reyes
Source:: Marine drugs 2019 v.18 no.1 pp. -
ISSN:: 1660-3397
Subject:: Mycobacterium tuberculosis; Staphylococcus aureus; Streptomyces; antibiotic resistance; bioactive compounds; biosynthesis; cytotoxicity; human cell lines; mass spectrometry; methicillin; microorganisms; molecular models; nuclear magnetic resonance spectroscopy
Abstract:: ... As part of our continuing efforts to discover new bioactive compounds from microbial sources, a reinvestigation of extracts of scaled-up cultures of the marine-derived Streptomyces sp. strain CA-271078 resulted in the isolation and structural elucidation of four new napyradiomycins (1–3, 5). The known napyradiomycin SC (4), whose structural details had not ...
DOI:: 10.3390/md18010022
: https://doi.org/10.3390/md18010022

79. A New Polyketide Antibiotic from the Marine Bacterium Streptomyces sp. PGC 32

Author:: Shabir Ahmad; Mamona Nazir; Muhammad Imran Tousif; Muhammad Saleem; Rizwana Mustafa; Tasneem Khatoon
Source:: Chemistry of natural compounds 2019 v.55 no.1 pp. 1-4
ISSN:: 0009-3130
Subject:: Bacillus subtilis; Enterobacter; Escherichia coli; Gram-negative bacteria; Gram-positive bacteria; Staphylococcus aureus; Streptomyces; antibacterial properties; antibiotics; aquatic bacteria; chemistry; culture media; mass spectrometry; metabolites; nuclear magnetic resonance spectroscopy; polyketides
Abstract:: ... A new aromatic polyketide compound, arabomycin (1), along with three known metabolites (2–4), was isolated from the culture broth of the marine bacterium Streptomyces sp. PGC 32. The structure of the new compound was established through 1D and 2D NMR analyses and high-resolution mass spectrometry, and the known compounds were elucidated on the basis of ¹H and ¹³C NMR information in comparison with ...
DOI:: 10.1007/s10600-019-02602-0
: https://doi.org/10.1007/s10600-019-02602-0

80. New antimicrobial anthraquinone 6,61-bis (1,5,7-trihydroxy-3-hydroxymethylanthraquinone) isolated from Streptomyces sp. isolate ERI-26

Author:: V. Duraipandiyan; Naif Abdullah Al-Dhabi; S. Ignacimuthu
Source:: Saudi Journal of Biological Sciences 2016 v.23 pp. 731-735
ISSN:: 1319-562X
Subject:: Aspergillus niger; Bacillus subtilis; Botrytis cinerea; Magnaporthe grisea; Staphylococcus aureus; Staphylococcus epidermidis; Streptomyces; Trichophyton mentagrophytes; Trichophyton rubrum; anthraquinones; antimicrobial properties; forests; fractionation; fungi; high performance liquid chromatography; methanol; microbial growth; nuclear magnetic resonance spectroscopy; silica gel; spectral analysis
Abstract:: ... The present report is about Streptomyces sp. isolate ERI-26 isolated from the soil sample of Nilgiri forest, Western Ghats. The methanol extract of ERI-26 showed good antimicrobial activity against tested microbes. The antimicrobial novel anthraquinones were purified by bioactivity-guided fractionation using a silica gel column and preparative HPLC. The compound was characterized and identified by ...
DOI:: 10.1016/j.sjbs.2016.02.008
PubMed:: 27872569
PubMed Central:: PMC5109497
: https://doi.org/10.1016/j.sjbs.2016.02.008

81. Nitricquinomycins A-C, uncommon naphthopyrrolediones from the Streptomyces sp. ZS-A45

Author:: Biao Zhou; Yun Huang; Hao-Jian Zhang; Jia-Qi Li; Wan-jing Ding
Source:: Tetrahedron 2019 v.75 no.30 pp. 3958-3961
ISSN:: 0040-4020
Subject:: Candida albicans; Escherichia coli; Staphylococcus aureus; Streptomyces; antibacterial properties; cell lines; chemical reactions; chemical structure; circular dichroism spectroscopy; cytotoxicity; fermentation; inhibitory concentration 50; marine sediments; minimum inhibitory concentration; nuclear magnetic resonance spectroscopy; organic compounds; quantum mechanics; rice
Abstract:: ... Nitricquinomycins A-C (1∼3), three uncommon naphthopyrrolediones, together with one new compound (4), were isolated from the modified rice solid fermentation of the marine-derived Streptomyces sp. ZS-A45, an actinobacterium isolated from the marine sediments collected from Zhoushan island. Their structures were elucidated on the basis of MS, NMR spectroscopic and quantum chemical calculations of t ...
DOI:: 10.1016/j.tet.2019.05.060
: https://doi.org/10.1016/j.tet.2019.05.060

82. Novel 1,5,7-Trihydroxy-3-Hydroxy Methyl Anthraquinone Isolated from Terrestrial Streptomyces sp. (eri-26) with Antimicrobial and Molecular Docking Studies

Author:: V. Duraipandiyan; N. A. AL-Dhabi; C. Balachandran; M. Karunai Raj; M. Valan Arasu; S. Ignacimuthu
Source:: Applied biochemistry and biotechnology 2014 v.174 no.5 pp. 1784-1794
ISSN:: 0273-2289
Subject:: antimicrobial properties; Staphylococcus aureus; nuclear magnetic resonance spectroscopy; Aspergillus niger; energy; Epidermophyton floccosum; Botrytis cinerea; beta-lactamase; minimum inhibitory concentration; Staphylococcus epidermidis; Trichophyton rubrum; Bacillus subtilis; forest soils; Streptomyces; anti-infective agents; anthraquinones; bacteria; fungi; India
Abstract:: ... Streptomyces sp. isolate ERI-26 was obtained from the Nilgiris forest soil of Western Ghats, Tamil Nadu, India. Novel anthraquinone compound was isolated from the active fraction 5; it was identified by spectroscopical data using UV, IR, NMR and MASS. The isolated compound 1,5,7-trihydroxy-3-hydroxy methyl anthraquinone was tested against bacteria and fungi at minimum inhibitory concentration leve ...
DOI:: 10.1007/s12010-014-1157-y
PubMed:: 25149455
: https://doi.org/10.1007/s12010-014-1157-y

83. Novel actinomycin group compound from newly isolated Streptomyces sp. RAB12: isolation, characterization, and evaluation of antimicrobial potential

Author:: Balaji Baburao Rathod; Ravichandra Korasapati; Prabhakar Sripadi; Prakasham Reddy Shetty
Source:: Applied microbiology and biotechnology 2018 v.102 no.3 pp. 1241-1250
ISSN:: 0175-7598
Subject:: Bacillus subtilis; Candida albicans; Micrococcus luteus; Pseudomonas aeruginosa; Salmonella Typhi; Staphylococcus aureus; Streptomyces; actinomycin D; antimicrobial properties; gardens; moieties; molecular weight; nuclear magnetic resonance spectroscopy; nucleotide sequences; proline; ribosomal RNA; soil sampling; India
Abstract:: ... Streptomyces sp. RAB12 having potential to produce novel actinomycin group compounds was isolated from soil samples collected from CSIR-Indian Institute of Chemical Technology, Hyderabad, India, garden premises using International Streptomycetes Project (ISP) protocols. The 16S rRNA sequence of the strain RAB12 exhibited identity with Streptomyces sp. 13647M and the sequence was deposited in NCBI ...
DOI:: 10.1007/s00253-017-8696-4
: https://doi.org/10.1007/s00253-017-8696-4

84. Pharacine, a natural p-cyclophane and other indole derivatives from Cytophaga sp. strain AM13.1

Author:: Shaaban, M.; Maskey, R.P.; Wagner-Dobler, I.; Laatsch, H.
Source:: Journal of natural products 2002 v.65 no.11 pp. 1660-1663
ISSN:: 0163-3864
Subject:: fatty acids; Staphylococcus aureus; algae; pyrazines; spectral analysis; strains; tryptamines; molecular conformation; secondary metabolites; Cytophaga marinoflava; stereochemistry; antifungal properties; Escherichia coli; Candida albicans; Streptomyces viridochromogenes; antibacterial properties; chemical composition; piperidines; Scenedesmus; ethers; seawater; Bacillus subtilis; Chlorella vulgaris; North Sea; Germany
DOI:: 10.1021/np020019a
PubMed:: 12444694
: https://doi.org/10.1021/np020019a

85. Phylogenetic analysis and antimicrobial activities of Streptomyces isolates from mangrove sediment

Author:: Satheeja, Santhi V.; Jebakumar, Solomon R.D.
Source:: Journal of basic microbiology 2011 v.51 no.1 pp. 71-79
ISSN:: 0233-111X
Subject:: Salmonella Typhi; Staphylococcus aureus; Streptomyces; anti-infective properties; antibiotic resistance; bacteria; estuaries; genes; methicillin; nucleotide sequences; phenotype; phylogeny; restriction fragment length polymorphism; ribosomal RNA; sediments; sequence analysis; Arabian Sea; India
Abstract:: ... The phylogeny of members of Streptomyces bacteria isolated from mangrove sediments in the Manakudi estuary near the Arabian Sea, India, was analyzed in the present study. Among the 35 different isolates, five organisms, JS-9, JS-11, JS-12, JS-13 and JS-20, exhibited potent antimicrobial effects against methicillin-resistant Staphylococcus aureus (clinical isolate) and methicillin-susceptible S. au ...
DOI:: 10.1002/jobm.201000107
: https://doi.org/10.1002/jobm.201000107

86. Population and function analysis of cultivable bacteria associated with spores of arbuscular mycorrhizal fungus Gigaspora margarita

Author:: Liangkun Long; Qunying Lin; Qing Yao; Honghui Zhu
Source:: 3 Biotech 2017 v.7 no.1 pp. 8
ISSN:: 2190-572X
Subject:: Bacillus (bacteria); Curtobacterium; Ensifer; Escherichia coli; Gigaspora margarita; Medicago sativa; Sorghum bicolor; Staphylococcus aureus; Streptomyces; Zea mays; alfalfa; bacteria; bacterial communities; chitin; corn; fungal spores; genes; grain sorghum; host plants; hyphae; mycorrhizal fungi; phosphorus; phylogeny; ribosomal RNA; roots; solubilization; spore germination; vermiculite
Abstract:: ... This study was aimed to investigate the diversity and function of bacterial population associated with Gigaspora margarita spores. The fungus was propagated in sterilized sand/soil pots using alfalfa (Medicago sativa), grain sorghum (Sorghum bicolor), or maize (Zea mays) as host plants, or in sterilized vermiculite pots using alfalfa as host plants, respectively. Bacteria were isolated from the ne ...
DOI:: 10.1007/s13205-017-0612-1
PubMed:: 28391471
PubMed Central:: PMC5385182
: https://doi.org/10.1007/s13205-017-0612-1

87. Potential anti-biofilm producing marine actinomycetes isolated from sea sediments in Thailand

Author:: Kantinan Leetanasaksakul; Arinthip Thamchaipenet
Source:: Agriculture and natural resources 2018 v.52 no.3 pp. 228-233
ISSN:: 2452-316X
Subject:: Actinopolymorpha; Dietzia; Escherichia coli; Micromonospora; Mycobacterium; Nocardiopsis; Pseudomonas aeruginosa; Staphylococcus aureus; Streptomyces; bacteria; bioactive compounds; biofilm; enzyme activity; nucleotide sequences; ribosomal DNA; sediments; sequence analysis; therapeutics; Andaman Sea; Thailand
Abstract:: ... Marine actinomycetes are well known as novel resources of bioactive compounds including anti-biofilm agents with various therapeutic applications. In this study, one hundred and one marine actinomycetes were isolated from sea sediments collected from Andaman sea and the Gulf of Thailand. Morphological study and partial 16S rDNA sequence analysis revealed that most of isolates belong to genus Strep ...
DOI:: 10.1016/j.anres.2018.09.003
: https://doi.org/10.1016/j.anres.2018.09.003

88. Prefluostatin and New Urauchimycin Derivatives Produced by Streptomycete Isolates

Author:: C. B. Fondja Yao; M. Schiebel; E. Helmke; H. Anke; H. Laatsch
Source:: Zeitschrift für Naturforschung 2014 v.61 no.3 pp. 320-325
ISSN:: 0932-0776
Subject:: Bacillus subtilis; Escherichia coli; Rhizomucor miehei; Staphylococcus aureus; Streptomyces; agar; bacteria; cytotoxicity; fungi; nuclear magnetic resonance spectroscopy; screening
Abstract:: ... Guided by chemical screening, two new members of the antimycin group, urauchimycin C (1b) and D (1a), were isolated from the marine-derived Streptomyces sp. isolate B1751 and from a terrestrial strain AdM21, together with prefluostatin (2), a new natural derivative of isoprekinamycin (4). Their structures were established on the basis of NMR data and by comparison with known compounds. In the agar ...
DOI:: 10.1515/znb-2006-0312
: https://doi.org/10.1515/znb-2006-0312

89. Production of macrolide antibiotics from a cytotoxic soil Streptomyces sp. strain ZDB

Author:: Zerihun T. Dame; Pornthip Ruanpanun
Source:: World journal of microbiology & biotechnology 2017 v.33 no.7 pp. 139
ISSN:: 0959-3993
Subject:: Artemia salina; Bacillus subtilis; Chlorella sorokiniana; Chlorella vulgaris; Escherichia coli; Staphylococcus aureus; Streptomyces; antimicrobial properties; cytotoxicity; fermentation; macrolide antibiotics; soil; spectral analysis
Abstract:: ... Crude extract from a culture of a soil Streptomyces sp. strain ZDB showed toxicity towards Artemia salina and antimicrobial activity against Escherichia coli, Bacillus subtilis, Staphylococcus aureus, Chlorella vulgaris, and Chlorella sorokiniana. Large scale fermentation of the strain led to the isolation of the macrolide antibiotics, bafilomycins A1 (1), B1 (2), and D (3) together with nonactic ...
DOI:: 10.1007/s11274-017-2306-6
: https://doi.org/10.1007/s11274-017-2306-6

90. Production of ramoplanin analogues by genetic engineering of Actinoplanes sp.

Author:: Hai-Xue Pan; Zhou-Zhou Chen; Lei Shao; Ji-An Li; Jun-Sheng Chen; Chun-Bao Zhu; Gong-Li Tang; Dai-Jie Chen
Source:: Biotechnology letters 2013 v.35 no.10 pp. 1685-1692
ISSN:: 0141-5492
Subject:: Actinoplanes; Staphylococcus aureus; Streptomyces fungicidicus; acyl coenzyme A; antimicrobial properties; clinical trials; genes; genetic engineering; mutants; pathogens
Abstract:: ... Ramoplanins are lipopeptides effective against a wide range of Gram-positive pathogens. Ramoplanin A2 is in Phase III clinical trials. The structure–activity relationship of the unique 2Z,4E-fatty acid side-chain of ramoplanins indicates a significant contribution to the antimicrobial activities but ramoplanin derivatives with longer 2Z,4E-fatty acid side-chains are not easy to obtain by semi-synt ...
DOI:: 10.1007/s10529-013-1261-z
PubMed:: 23801115
: https://doi.org/10.1007/s10529-013-1261-z

91. Production of vineomycin A1 and chaetoglobosin A by Streptomyces sp. PAL114

Author:: Adel Aouiche; Atika Meklat; Christian Bijani; Abdelghani Zitouni; Nasserdine Sabaou; Florence Mathieu
Source:: Annals of microbiology 2015 v.65 no.3 pp. 1351-1359
ISSN:: 1590-4261
Subject:: Bacillus subtilis; Calonectria; Candida albicans; Chaetomium; Penicillium; Staphylococcus aureus; Streptomyces; antibiotics; carbon; chemical structure; cytotoxicity; fungi; high performance liquid chromatography; methylene chloride; minimum inhibitory concentration; nuclear magnetic resonance spectroscopy; nucleotide sequences; prokaryotic cells; ribosomal RNA; soil; stable isotopes; toxigenic strains; Algeria
Abstract:: ... An actinobacteria strain PAL114, isolated from a Saharan soil in Algeria, produces bioactive compounds. Morphological and chemical studies indicated that this strain belongs to the genus Streptomyces. Analysis of the 16S rRNA gene sequence showed a similarity level of 99.8 % with S. griseoflavus LMG 19344ᵀ, the most closely related species. Two bioactive compounds, named P44 and P40, were extracte ...
DOI:: 10.1007/s13213-014-0973-1
: https://doi.org/10.1007/s13213-014-0973-1

92. Profiling of red pigment produced by Streptomyces sp. JAR6 and its bioactivity

Author:: Jayanthi Abraham; Ritika Chauhan
Source:: 3 Biotech 2018 v.8 no.1 pp. 22
ISSN:: 2190-572X
Subject:: Enterococcus; Escherichia coli; Klebsiella pneumoniae; Proteus mirabilis; Salmonella; Shigella; Staphylococcus aureus; Streptomyces; antimicrobial properties; antineoplastic activity; bioactive compounds; chromatography; cytotoxicity; human cell lines; inhibitory concentration 50; metabolites; minimum inhibitory concentration; plant litter; solid state fermentation; spectral analysis
Abstract:: ... Actinomycetes strain was isolated from leaf litter soil sample and was identified as Streptomyces sp. by conventional and molecular approaches. The biologically active compound responsible for antimicrobial and anticancer activity of the strain JAR6 was elucidated by solid state fermentation followed by subsequent chromatographic and spectroscopic analysis. Extraction, purification and structural ...
DOI:: 10.1007/s13205-017-1044-7
PubMed:: 29276660
PubMed Central:: PMC5735041
: https://doi.org/10.1007/s13205-017-1044-7

93. Purification, structure determination, and antimicrobial activity of neutramycins B-G

Author:: Graziani, E.I.; Overk, C.R.; Carter, G.T.
Source:: Journal of natural products 2003 v.66 no.9 pp. 1149-1153
ISSN:: 0163-3864
Subject:: glycosidic linkages; sugars; antibiotics; carbon; spectral analysis; protons; stereochemistry; metabolites; Streptomyces luteoverticillatus
DOI:: 10.1021/np0301691
PubMed:: 14510587
: https://doi.org/10.1021/np0301691

94. Saccharothrix algeriensis NRRL B-24137, the first non-Streptomyces actinobacterium, produces holomycin after cystine feeding

Author:: Rabiâa Merrouche; Amine Yekkour; Yannick Coppel; Noureddine Bouras; Abdelghani Zitouni; Florence Mathieu; Nasserdine Sabaou
Source:: Archives of microbiology 2020 v.202 no.9 pp. 2509-2516
ISSN:: 0302-8933
Subject:: Aspergillus carbonarius; Candida albicans; Escherichia coli; Fusarium culmorum; Klebsiella pneumoniae; Listeria monocytogenes; Saccharothrix; Staphylococcus aureus; Streptomyces; antibiotics; antimicrobial properties; culture media; cysteine; cystine; fungi; soil
Abstract:: ... Saccharothrix algeriensis NRRL B-24137 is an actinobacterium isolated from Algerian Saharan soil. This strain has the ability to produce several dithiolopyrrolone antibiotic derivatives depending on the precursors added to the culture medium. This group of antibiotics is known for their potent antimicrobial and anticancer activities. Holomycin is a member of the dithiolopyrrolone group of antibiot ...
DOI:: 10.1007/s00203-020-01971-3
: https://doi.org/10.1007/s00203-020-01971-3

95. Selective isolation and characterisation of novel members of the family Nocardiopsaceae and other actinobacteria from a marine sediment of Tioman Island

Author:: Zoe Yi Ng; Geok Yuan Annie Tan
Source:: Antonie van Leeuwenhoek 2018 v.111 no.5 pp. 727-742
ISSN:: 0003-6072
Subject:: Agromyces; Bacillus subtilis; Blastococcus; Nocardiopsis; Nonomuraea; Providencia alcalifaciens; Staphylococcus aureus; Streptomyces; bioactive properties; digestion; fosfomycin; marine sediments; new genus; pathogens; phylogeny; ribosomal DNA; ribosomal RNA; sequence analysis; skim milk; Malaysia
Abstract:: ... Tioman Island is one of many sources for underexplored actinobacterial diversity in Malaysia. Selective isolation, molecular profiling, 16S rRNA gene sequencing and phylogenetic analyses were carried out to highlight the diversity of the marine actinobacterial community in a sediment collected off Tioman Island. A high number of diverse actinobacteria were recovered using skim milk/HEPES pre-treat ...
DOI:: 10.1007/s10482-018-1042-8
: https://doi.org/10.1007/s10482-018-1042-8

96. Short Communication: Antibacterial potential of Actinomycetes isolated from mangrove sediment in Tanjung Api-Api, South Sumatra, Indonesia

Author:: ROZIRWAN Rozirwan; Hebbri Iskandar Muda; Tengku Zia Ulqodry
Source:: Biodiversitas 2020 v.21 no.12 pp. -
ISSN:: 2085-4722
Subject:: Actinomyces; Corynebacterium; Escherichia coli; Jonesia; Micrococcus; Nocardia; Staphylococcus aureus; Streptomyces; anaerobes; antibacterial properties; glucose; growth retardation; mangrove sediments; organic matter; Indonesia
Abstract:: ... Rozirwan, Muda HI, Ulqodry TZ. 2020. Short Communication: Antibacterial potential of Actinomycetes isolated from mangrove sediment in Tanjung Api-Api, South Sumatra, Indonesia. Biodiversitas 21: 5723-5728. Actinomycetes play an important role in the decomposition process of organic matter in mangrove sediments. This study was carried out to identify and evaluate the antagonistic activity of actino ...
DOI:: 10.13057/biodiv/d211232
: https://doi.org/10.13057/biodiv/d211232

97. Statistical optimization of a multivariate fermentation process for enhancing antibiotic activity of Streptomyces sp. CS392

Author:: Poonam Mander; Yun Hee Choi; Jeong Heon Seong; Baek Hee Na; Seung Sik Cho; Hyo Jeong Lee; Jin Cheol Yoo
Source:: Archives of pharmacal research 2013 v.36 no.8 pp. 973-980
ISSN:: 0253-6269
Subject:: Enterococcus; Gram-positive bacteria; Staphylococcus aureus; Streptomyces; antibacterial properties; casamino acids; culture media; fermentation; glucose; models; nutrient content; pH; peptones; response surface methodology; temperature
Abstract:: ... Antibiotic activity against various gram positive bacteria including Staphylococcus aureus and Enterococcus was ascertained from a soil-isolated microbial strain Streptomyces sp. CS392. The antibiotic activity of the strain was maximized by using a dual-stage, multivariate statistical optimization framework based on the response surface methodology considering a lab-scale fermentation process. Mul ...
DOI:: 10.1007/s12272-013-0140-4
: https://doi.org/10.1007/s12272-013-0140-4

98. Studies on Terpenoids Produced by Actinomycetes: Oxaloterpins A, B, C, D, and E, Diterpenes from Streptomyces sp. KO-3988

Author:: Motohashi, K.; Ueno, R.; Sue, M.; Furihata, K.; Matsumoto, T.; Dairi, T.; Omura, S.; Seto, H.
Source:: Journal of natural products 2007 v.70 no.11 pp. 1712-1717
ISSN:: 0163-3864
Subject:: Staphylococcus aureus; diterpenoids; Bacillus subtilis; spectral analysis; Streptomyces; chemical structure; stereochemistry; antibacterial properties
DOI:: 10.1021/np070326m
PubMed:: 17970596
: https://doi.org/10.1021/np070326m

99. Synthesis, characterization and evaluation of antimicrobial and cytotoxic activities of biogenic silver nanoparticles synthesized from Streptomyces xinghaiensis OF1 strain

Author:: Magdalena Wypij; Joanna Czarnecka; Magdalena Świecimska; Hanna Dahm; Mahendra Rai; Patrycja Golinska
Source:: World journal of microbiology & biotechnology 2018 v.34 no.2 pp. 23
ISSN:: 0959-3993
Subject:: Bacillus subtilis; Candida albicans; Escherichia coli; Fourier transform infrared spectroscopy; Klebsiella pneumoniae; Malassezia furfur; Pseudomonas aeruginosa; Staphylococcus aureus; Streptomyces; antibiotics; antifungal properties; bacteria; cytotoxicity; dose response; fibroblasts; human cell lines; inhibitory concentration 50; mice; minimum inhibitory concentration; nanomedicine; nanosilver; neoplasms; organic compounds; synergism; therapeutics; transmission electron microscopy; ultraviolet-visible spectroscopy; yeasts
Abstract:: ... We report synthesis of silver nanoparticles (AgNPs) from Streptomyces xinghaiensis OF1 strain, which were characterised by UV–Vis and Fourier transform infrared spectroscopy, Zeta sizer, Nano tracking analyser, and Transmission electron microscopy. The antimicrobial activity of AgNPs alone, and in combination with antibiotics was evaluated against bacteria, namely Escherichia coli, Pseudomonas aer ...
DOI:: 10.1007/s11274-017-2406-3
PubMed:: 29305718
PubMed Central:: PMC5756267
: https://doi.org/10.1007/s11274-017-2406-3

100. Taxonomy of actinomycetes in the deep-sea Calyptogena communities and characterization of the antibacterial compound produced by Actinomadura sp. DS-MS-114

Author:: Atsushi Kurata; Miwa Sugiura; Kento Kokoda; Hiroaki Tsujimoto; Tetsuya Numata; Chiaki Kato; Kaoru Nakasone; Noriaki Kishimoto
Source:: Biotechnology, biotechnological equipment 2017 v.31 no.5 pp. 1000-1006
ISSN:: 1314-3530
Subject:: Actinomadura; Aeromicrobium; Japan; Micromonospora; Nocardioides; Staphylococcus aureus; Streptomyces; antibiotics; biotechnology; electrospray ionization mass spectrometry; equipment; immunosuppressive agents; marine sediments; nuclear magnetic resonance spectroscopy; taxonomy
Abstract:: ... Fifteen actinomycetes were isolated from deep-sea sediments in Calyptogena communities in the Japan Trench (depth: 5352 m) and Sagami Bay (depth: 1171 m) under incubation at 4–37 °C. A relatively large number of colonies were obtained with incubation at 30 °C from the deep-sea sediment of Sagami Bay. We found Rhodococcus, Nocardioides and Micromonospora actinomycetes in both sediments, and additio ...
DOI:: 10.1080/13102818.2017.1342563
: https://doi.org/10.1080/13102818.2017.1342563

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1. Additional pyrrolomycins from cultures of Streptomyces fumanus

2. Aldgamycins J–O, 16-Membered Macrolides with a Branched Octose Unit from Streptomycetes sp. and Their Antibacterial Activities

3. Angucycline antibiotics and its derivatives from marine-derived actinomycete Streptomyces sp. A6H

4. Antibacterial Activity of Streptomyces SAE4034 Isolated from Segara Anakan Mangrove Rhizosphere against Antibiotic Resistant Bacteria

5. Antibacterial Activity of Streptomyces sp. VITMK1 Isolated from Mangrove Soil of Pichavaram, Tamil Nadu, India

6. Antibacterial Cyclic Lipopeptide Enamidonins with an Enamide-Linked Acyl Chain from a Streptomyces Species

7. Antibacterial Meroterpenoids, Merochlorins G–J from the Marine Bacterium Streptomyces sp.

8. Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471

9. Antibacterial and antifungal activities of polyketide metabolite from marine Streptomyces sp. AP-123 and its cytotoxic effect

10. Antibacterial, antioxidant and anticancer activities of biphenyls from Streptomyces sp. BO-07: an endophyte in Boesenbergia rotunda (L.) Mansf A.

11. Antimicrobial Activities of Marine Sponge-Associated Bacteria

12. Antimicrobial Activity of Marine Bacterial Symbionts Retrieved from Shallow Water Hydrothermal Vents

13. Antimicrobial and Cytotoxicity Properties of 2,3-Dihydroxy-9,10-Anthraquinone Isolated from Streptomyces galbus (ERINLG-127)

14. Antimicrobial and cytotoxic activity of silver nanoparticles synthesized from two haloalkaliphilic actinobacterial strains alone and in combination with antibiotics

15. Antimicrobial investigation of selected soil actinomycetes isolated from unexplored regions of Kashmir Himalayas, India

16. Antimicrobial lavandulylated flavonoids from a sponge-derived actinomycete

17. Antimicrobial metabolites from a marine-derived Actinomycete Streptomyces sp. G278

18. Antitumour and antimicrobial activities of endophytic streptomycetes from pharmaceutical plants in rainforest

19. Arthroamide, a Cyclic Depsipeptide with Quorum Sensing Inhibitory Activity from Arthrobacter sp.

20. Azodyrecins A–C: Azoxides from a Soil-Derived Streptomyces Species

21. Bioactive potential of Streptomyces associated with marine sponges

22. Biosynthesis of Silver Nanoparticles Using The Cell-Free Filtrate of Streptomyces atacamensis: Characterization and Antibacterial Activity

23. Biosynthesis of mercapturic acid derivative of the labdane-type diterpene, cyslabdan that potentiates imipenem activity against methicillin-resistant Staphylococcus aureus: cyslabdan is generated by mycothiol-mediated xenobiotic detoxification

24. Biosynthesis, characterization and antimicrobial activity of silver nanoparticles by Streptomyces sp. SS2

25. Broad-spectrum In vitro antimicrobial activities of Streptomyces sp. strain BCNU 1001

26. Catalytic Site Cooperativity in Dimeric Methylthioadenosine Nucleosidase

27. Comparative Analysis of Antimicrobial Activities of Valinomycin and Cereulide, the Bacillus cereus Emetic Toxin

28. Comparative analysis of the relationship between translation efficiency and sequence features of endogenous proteins in multiple organisms

29. Cyclic Hexapeptides from the Deep South China Sea-Derived Streptomyces scopuliridis SCSIO ZJ46 Active Against Pathogenic Gram-Positive Bacteria

30. Daryamides A-C, Weakly Cytotoxic Polyketides from a Marine-Derived Actinomycete of the Genus Streptomyces Strain CNQ-085

31. Detection of the antibacterial effect of Chaetomium cochliodes Palliser CCM F-232 based on agar plugs and unprocessed fungal substances from cultivation media

32. Detection, selective isolation and characterisation of Dactylosporangium strains from diverse environmental samples

33. Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15

34. Discovery and evaluation on the antibacterial and cytotoxic activities of a novel antifungalmycin N2 produced from Streptomyces sp. strain N2

35. Diversity and Antimicrobial Activity of Endophytic Actinomycetes Isolated from Plant Roots in Thailand

36. Diversity of Culturable Thermophilic Actinobacteria in Hot Springs in Tengchong, China and Studies of their Biosynthetic Gene Profiles

37. Endophytic Streptomyces in the traditional medicinal plant Arnica montana L.: secondary metabolites and biological activity

38. Engineered biosynthesis of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities

39. Enhanced Production of Antimicrobial Compounds by Three Salt-Tolerant Actinobacterial Strains Isolated from the Sundarbans in a Niche-Mimic Bioreactor

40. Enzyme production, antibacterial and antifungal activities of actinobacteria isolated from Ficus deltoidea rhizosphere

41. Evaluating the effect of various bacterial consortia on antibacterial activity of marine Streptomyces sp. AC117

42. Evaluation of Microbiological Quality of Vermicompost Prepared from Different Types of Organic Wastes using Eisenia fetida

43. Exploring Actinobacteria from North-Western Himalayas in Quest of Novel Pharmacophores

44. Ficellomycin: an aziridine alkaloid antibiotic with potential therapeutic capacity

45. Functional gene-based discovery of phenazines from the actinobacteria associated with marine sponges in the South China Sea

46. Genomic insights into the biosynthesis and physiology of the cyanobacterial neurotoxin 3-N-methyl-2,3-diaminopropanoic acid (BMAA)

47. Genomics-Driven Discovery of Chlorinated Cyclic Hexapeptides Ulleungmycins A and B from a Streptomyces Species

48. Gephyyamycin and cysrabelomycin, two new angucyclinone derivatives from the Streptomyces sp. HN-A124

49. Gram-positive aerobic and microaerophilic microorganisms isolated from pathological processes and lesions of horses

50. Green biosynthesis of silver nanoparticles produced from marine Streptomyces sp. Al-Dhabi-89 and their potential applications against wound infection and drug resistant clinical pathogens

51. Gwanakosides A and B, 6-Deoxy-α-l-talopyranose-Bearing Aromatic Metabolites from a Streptomyces sp. and Coculture with Pandoraea sp.

52. Halophilic and halotolerant actinomycetes from a marine saltern of Goa, India producing anti-bacterial metabolites

53. Hygrocin C from marine-derived Streptomyces sp. SCSGAA 0027 inhibits biofilm formation in Bacillus amyloliquefaciens SCSGAB0082 isolated from South China Sea gorgonian

54. Identification and Characterization of the Anti-Methicillin-Resistant Staphylococcus aureus WAP-8294A2 Biosynthetic Gene Cluster from Lysobacter enzymogenes OH11

55. Identification and characterization of the ficellomycin biosynthesis gene cluster from Streptomyces ficellus

56. Identification of Elaiophylin Skeletal Variants from the Indonesian Streptomyces sp. ICBB 9297

57. In Situ Cultured Bacterial Diversity from Iron Curtain Cave, Chilliwack, British Columbia, Canada

58. In vitro activity of 5-(2,4-dimethylbenzyl) pyrrolidin-2-one extracted from marine Streptomyces VITSVK5 spp. against fungal and bacterial human pathogens

59. Inhibition of Staphylococcus aureus by antimicrobial biofilms formed by competitive exclusion microorganisms on stainless steel

60. Inhibition of bacterial RNA polymerases. Peptide metabolites from the cultures of Streptomyces sp

61. Intra‐clade metabolomic profiling of MAR4 Streptomyces from the Macaronesia Atlantic region reveals a source of anti‐biofilm metabolites

62. Isolation and Structural Determination of Makinolide B from Streptomyces sp. MK-19

63. Isolation and characterization of anti-methicillinresistant Staphylococcus aureus/vancomycinresistant Enterococcus compound from Streptomyces bungoensis MJM 2077

64. Isolation and characterization of wastewater sand filter actinomycetes

65. Isolation and diversity of natural product biosynthetic genes of cultivable bacteria associated with marine sponge Mycale sp. from the coast of Fujian, China

66. Isolation and partial purification of erythromycin from alkaliphilic Streptomyces werraensis isolated from Rajkot, India

67. Ligiamycins A and B, Decalin-Amino-Maleimides from the Co-Culture of Streptomyces sp. and Achromobacter sp. Isolated from the Marine Wharf Roach, Ligia exotica

68. MS Analysis and Molecular Characterization of Botrytis cinerea Protease Prot-2. Use in Bioactive Peptides Production

69. Marmycins A and B, Cytotoxic Pentacyclic C-Glycosides from a Marine Sediment-Derived Actinomycete Related to the Genus Streptomyces

70. Meliponamycins: Antimicrobials from Stingless Bee-Associated Streptomyces sp.