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1. -Poly-l-Lysine Enhances Fruit Disease Resistance in Postharvest Longans (Dimocarpus longan Lour.) by Modulating Energy Status and ATPase Activity

Author:
Junzheng Sun; Hongbin Chen; Yihui Chen; Mengshi Lin; Yen-Con Hung; Yuji Jiang; Hetong Lin
Source:
Foods 2022 v.11 no.5 pp. -
ISSN:
2304-8158
Subject:
Diaporthe; Dimocarpus longan; adenosine diphosphate; adenosine monophosphate; adenosine triphosphate; adenosinetriphosphatase; ambient temperature; antibacterial properties; disease occurrence; disease resistance; energy; energy metabolism; food preservation; fruits; longans; mitochondria; vacuoles
Abstract:
... -poly-l-lysine (-PL) holds a strong antibacterial property and is widely used for food preservation. However, the application of -PL to enhance fruit disease resistance in postharvest longans (Dimocarpus longan Lour.) has not been explored. The objective of this study was to explore the impact of -PL treatment on disease occurrence and energy metabolism of longans infected with Phomopsis longanae ...
DOI:
10.3390/foods11050773

2. Alpha-tocotrienol enhances arborization of primary hippocampal neurons via upregulation of Bcl-xL

Author:
Han-A Park; Kristi M. Crowe-White; Lukasz Ciesla; Madison Scott; Sydni Bannerman; Abigail U. Davis; Bishnu Adhikari; Garrett Burnett; Katheryn Broman; Khondoker Adeba Ferdous; Kimberly H. Lackey; Pawel Licznerski; Elizabeth A. Jonas
Source:
Nutrition research 2022 v.101 pp. 31-42
ISSN:
0271-5317
Subject:
B-lymphocytes; adenosine triphosphate; alpha-tocotrienol; brain; death; energy; homeostasis; ischemia; mitochondria; neurites; neurodegenerative diseases; neuroprotective effect; nutrition research; oxidative stress; rats; synaptic transmission; viability
Abstract:
... Alpha-tocotrienol (α-TCT) is a member of the vitamin E family. It has been reported to protect the brain against various pathologies including cerebral ischemia and neurodegeneration. However, it is still unclear if α-TCT exhibits beneficial effects during brain development. We hypothesized that treatment with α-TCT improves intracellular redox homeostasis supporting normal development of neurons. ...
DOI:
10.1016/j.nutres.2022.02.007

3. Antibacterial Effect of Oregano Essential Oil against Vibrio vulnificus and Its Mechanism

Author:
Kunyao Luo; Pengyu Zhao; Yifei He; Shengnan Kang; Chenyu Shen; Shuo Wang; Meixian Guo; Lehui Wang; Chao Shi
Source:
Foods 2022 v.11 no.3 pp. -
ISSN:
2304-8158
Subject:
DNA; DNA damage; Vibrio vulnificus; adenosine triphosphate; antibacterial properties; antibiotics; cell membranes; lipid peroxidation; malondialdehyde; oregano oil; permeability; reactive oxygen species
Abstract:
... Oregano essential oil (OEO) is an effective natural antibacterial agent, but its antibacterial activity against Vibrio vulnificus has not been widely studied. The aim of this study was to investigate the inhibitory effect and germicidal activity of OEO on V. vulnificus and its possible inhibition mechanism. The minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) ...
DOI:
10.3390/foods11030403

4. Antibacterial mechanism of Protocatechuic acid against Yersinia enterocolitica and its application in pork

Author:
Mi Wu; Lu Tian; Jiapeng Fu; Sichen Liao; Hui Li; Zhongchao Gai; Guoli Gong
Source:
Food control 2022 v.133 pp. 108573
ISSN:
0956-7135
Subject:
Yersinia enterocolitica; adenosine triphosphate; amino acids; antibacterial properties; biosynthesis; cell membranes; energy metabolism; food industry; food safety; gene expression regulation; membrane permeability; metabolites; metabolomics; minimum inhibitory concentration; pH; pork; protocatechuic acid
Abstract:
... Protocatechuic acid (PCA) has adequate antibacterial activity against foodborne pathogens; however, its antibacterial mechanism has been rarely investigated. Therefore, this study attempts to elucidate the antibacterial mechanism of PCA against Yersinia enterocolitica. The corresponding results showed that PCA had a satisfactory antibacterial effect on Y. enterocolitica with a minimum inhibitory c ...
DOI:
10.1016/j.foodcont.2021.108573

5. Brain single-nucleus transcriptomics highlights that polystyrene nanoplastics potentially induce Parkinson’s disease-like neurodegeneration by causing energy metabolism disorders in mice

Author:
Boxuan Liang; Yuji Huang; Yizhou Zhong; Zhiming Li; Rongyi Ye; Bo Wang; Bingli Zhang; Hao Meng; Xi Lin; Jiaxin Du; Manjiang Hu; Qinghong Wu; Haixia Sui; Xingfen Yang; Zhenlie Huang
Source:
Journal of hazardous materials 2022 v.430 pp. 128459
ISSN:
0304-3894
Subject:
RNA; adenosine triphosphate; astrocytes; body weight; brain; energy metabolism; humans; metabolic diseases; mice; mitochondria; nanoplastics; neurotoxicity; oligodendroglia; pathogenesis; polystyrenes; transcriptomics; turbulent flow
Abstract:
... With the prevalence of nanoplastics in daily life, human exposure is inevitable. However, whether and how nanoplastics cause neurotoxicity in humans remains obscure. Herein, we conducted a 28-day repeated dose oral toxicity study in C57BL/6 J mice exposed to 0.25–250 mg/kg body weight (BW) polystyrene nanoplastics (PS-NPs, 50 nm). We revealed that PS-NP-caused Parkinson’s disease (PD)-like neurode ...
DOI:
10.1016/j.jhazmat.2022.128459

6. Chronic microglial inflammation promotes neuronal lactate supply but impairs its utilization in primary rat astrocyte-neuron co-cultures

Author:
Yi Wang; Jie Li; Meng-Yue Wang; Zhi-Yong Pan; Zhi-Qiang Li; Ze-Fen Wang
Source:
Biochemical and biophysical research communications 2022 v.607 pp. 28-35
ISSN:
0006-291X
Subject:
adenosine triphosphate; astrocytes; coculture; cytoskeleton; energy; energy metabolism; glucose; inflammation; lactic acid; lipopolysaccharides; neurons; neurotoxicity; oxidation; rats; research
Abstract:
... Neuronal activity is closely associated with energy metabolism. In addition to glucose, astrocyte-derived lactate serves as an energy source for neurons. Chronic inflammation is a common pathological event that is associated with aging and neurodegenerative diseases. However, the mechanisms underlying inflammation-induced neuronal injury are not fully understood. Both microglia and astrocytes part ...
DOI:
10.1016/j.bbrc.2022.03.122

7. Cloning and expression analysis of hif-1α and downstream genes during hypoxic stress in cobia (Rachycentron canadum)

Author:
Jian-sheng Huang; Eric Amenyogbe; Lin-tong Yang; Zhong-liang Wang; Gang Chen; Wei-zheng Wang; Jian-dong Zhang
Source:
Aquaculture international 2022 v.30 no.2 pp. 803-824
ISSN:
0967-6120
Subject:
Rachycentron canadum; adenosine triphosphate; amino acid sequences; amino acids; aquaculture; energy; erythropoietin; gene expression; genes; glycolysis; homeostasis; hypoxia; intestines; liver; muscles; oxygen; spleen; vascular endothelial growth factors
Abstract:
... Hypoxia is a lack of required oxygen to meet the metabolic demands of living organisms. Cellular hypoxia occurs when the molecular oxygen, essential to maintain sufficient adenosine triphosphate (ATP) levels for normal physiological function, surpasses the vascular supply. Tissue hypoxia can arise during a range of diseases. As molecular oxygen is a crucial metabolic energy source for all living o ...
DOI:
10.1007/s10499-021-00820-4

8. Contribution of extracellular polymeric substances and microbial community on the safety of drinking water quality: By mean of Cu/activated carbon biofiltration

Author:
Zhihao Bi; Tong Li; Xueci Xing; Peng Qi; Zesong Li; Chun Hu; Xiaoran Xu; Zhimin Sun; Gang Xu; Chaoxiang Chen; Kunyu Ma
Source:
Chemosphere 2022 v.286 pp. 131686
ISSN:
0045-6535
Subject:
activated carbon; adenosine triphosphate; adsorption; biofilm; biofiltration; chlorine; disinfection; hydrophobicity; microbial biomass; microbial communities; pollutants; polymers; secretion; tap water; water distribution; water quality
Abstract:
... Change in water quality was investigated with laboratory-scale ozone-biological activated carbon filters using copper-modified granular activated carbon (Cu/GAC) and unmodified granular activated carbon (GAC). In the first seven days of the experimental period, Cu/GAC removed organic matter more efficiently owing to its enhanced adsorption capacity. As the running time increased, the amount of dis ...
DOI:
10.1016/j.chemosphere.2021.131686

9. Dengzhan Xixin injection derived from a traditional Chinese herb Erigeron breviscapus ameliorates cerebral ischemia/reperfusion injury in rats via modulation of mitophagy and mitochondrial apoptosis

Author:
Lu Yang; Yiwen Tao; Liuling Luo; Yi Zhang; Xiaobo Wang; Xianli Meng
Source:
Journal of ethnopharmacology 2022 v.288 pp. 114988
ISSN:
0378-8741
Subject:
Erigeron breviscapus; Oriental traditional medicine; Western blotting; adenosine triphosphate; animal models; apoptosis; blood flow; brain; caffeic acid; caspase-3; complications (disease); fluorescent antibody technique; high performance liquid chromatography; infarction; ischemia; lysosomes; malondialdehyde; membrane potential; mitochondria; mitochondrial DNA; mitochondrial membrane; mitophagy; neurons; protein synthesis; quantitative polymerase chain reaction; reactive oxygen species; reperfusion injury; superoxide dismutase; therapeutics; transmission electron microscopy; ultrastructure; China
Abstract:
... Dengzhan Xixin injection (DX), a preparation of extracts from traditional Chinese medicine Erigeron breviscapus (Vaniot) Hand.-Mazz., has been widely used in clinical treatment of cerebral ischemia sequelae in China for a long history. However, its underlying mechanisms remain unclear. The objective of this present study aimed to investigate the therapeutic effects of DX on cerebral ischemia/reper ...
DOI:
10.1016/j.jep.2022.114988

10. Distinctive differences in the granulation of saline and non-saline enriched anaerobic ammonia oxidizing (AMX) bacteria

Author:
Victory Fiifi Dsane; Sumin An; Younggyun Choi
Source:
Journal of environmental sciences (China) 2022 v.122 pp. 162-173
ISSN:
1001-0742
Subject:
adenosine triphosphate; adenosinetriphosphatase; ammonia; ammonium; biomass; microbial communities; nitrogen; polymers; wastewater; China
Abstract:
... The growing interest in the anaerobic ammonium oxidizing (AMX) process in treating high nitrogen containing wastewaters and a comprehensive study into the granulation mechanism of these bacteria under diverse environmental conditions over the years have been unequal. To this effect, the distinctive differences in saline adapted AMX (S_AMX) and non-saline adapted AMX (NS_AMX) granules are presented ...
DOI:
10.1016/j.jes.2021.08.057

11. Effect of surfactants on phosphorus release and acidogenic fermentation of waste activated sludge containing different aluminium phosphate forms

Author:
Qian Ping; Jingyi Zhang; Ruijie Tang; Shuting Liao; Zhipeng Zhang; Yongmei Li
Source:
Chemosphere 2022 v.287 pp. 132213
ISSN:
0045-6535
Subject:
Citrobacter; acetates; activated sludge; adenosine triphosphate; aluminum; aluminum phosphate; citrates; fermentation; phosphorus; propionic acid; rhamnolipids; surfactants; wastewater treatment; Alps region
Abstract:
... The effects of different surfactants (rhamnolipid, trehalolipid and citrate) on phosphorus (P) release and acidogenic fermentation of waste activated sludge (WAS) containing different aluminium phosphate forms (AlPO₄, Al(PO₃)₃) were investigated. Results showed that rhamnolipid was the most effective surfactant to release P from aluminum phosphates (AlPs)-rich sludge. Al(PO₃)₃ was easier to releas ...
DOI:
10.1016/j.chemosphere.2021.132213

12. Effects of Oral Creatine Supplementation on Power Output during Repeated Treadmill Sprinting

Author:
Gregory C. Bogdanis; Mary E. Nevill; George Aphamis; Pinelopi S. Stavrinou; David G. Jenkins; Christoforos D. Giannaki; Henryk K. A. Lakomy; Clyde Williams
Source:
Nutrients 2022 v.14 no.6 pp. -
ISSN:
2072-6643
Subject:
adenosine triphosphate; ammonia; body weight; creatine; glucose; glycolysis; lactic acid; placebos
Abstract:
... The aim of the present study was to examine the effects of creatine (Cr) supplementation on power output during repeated sprints on a non-motorized treadmill. Sixteen recreationally active males volunteered for this study (age 25.5 ± 4.8 y, height 179 ± 5 cm, body mass 74.8 ± 6.8 kg). All participants received placebo supplementation (75 mg of glucose·kg⁻¹·day⁻¹) for 5 days and then performed a ba ...
DOI:
10.3390/nu14061140

13. Effects of pyruvate on early embryonic development and zygotic genome activation in pigs

Author:
Tianrui Zhang; Yingying Zheng; Rui Han; Tianya Kuang; Changguo Min; Heming Wang; Yicheng Zhao; Junjun Wang; Lianyu Yang; Dongsheng Che
Source:
Theriogenology 2022 v.189 pp. 77-85
ISSN:
0093-691X
Subject:
acetylation; adenosine triphosphate; animal reproduction; data collection; embryogenesis; energy; lactic acid; methylation; oxidative stress; pyruvic acid; reactive oxygen species; sequence analysis; swine
Abstract:
... Pyruvate is an important energy substance during early embryonic development of mammals. However, the underlying mechanisms of pyruvate during early embryonic development in pigs and its role in zygotic genome activation (ZGA) are not fully understood. Here, based on a previous RNA-seq dataset of porcine early embryos, we found that pyruvate metabolism-related genes started to be expressed at the ...
DOI:
10.1016/j.theriogenology.2022.06.013

14. Environmental free radicals efficiently inhibit the conjugative transfer of antibiotic resistance by altering cellular metabolism and plasmid transfer

Author:
Hu Li; Ruiying Song; Yangyang Wang; Rongwei Zhong; Tiecheng Wang; Hanzhong Jia; Lingyan Zhu
Source:
Water research 2022 v.209 pp. 117946
ISSN:
0043-1354
Subject:
Escherichia coli; adenosine triphosphate; antibiotic resistance; enzymes; free radicals; metabolism; plasmids; polymers; polysaccharides; public safety; research; water
Abstract:
... Spread of antibiotic-resistant genes (ARGs) is a global public safety issue and inhibition their transfer is imperative. In this study, a novel strategy using environmental free radical exposure was developed to inhibit conjugative transfer of ARGs (RP4 plasmid) in aqueous solutions. Long-time free radical (·OH, ¹O₂, and O₂·⁻) exposure significantly suppressed the conjugative transfer frequency of ...
DOI:
10.1016/j.watres.2021.117946

15. Evaluation of disinfection byproducts for their ability to affect mitochondrial function

Author:
George William Kajjumba; Rachael E. Bokota; Matias Attene-Ramos; Erica J. Marti
Source:
Journal of environmental sciences (China) 2022 v.117 pp. 295-304
ISSN:
1001-0742
Subject:
adenosine triphosphate; analytical methods; carcinoma; cytotoxicity; disinfection; drinking water; environmental monitoring; haloacetic acids; humans; membrane potential; mitochondria; mitochondrial membrane; nitrosamines; water quality; water reuse; China
Abstract:
... In the race to deliver clean water to communities through potable water reuse, disinfection and water quality assessment are and will continue to be fundamental factors. There are over 700 disinfection byproducts (DBPs) in water; evaluating each compound is practically impossible and very time consuming. A bioanalytical approach could be an answer to this challenge. In this work, the response of f ...
DOI:
10.1016/j.jes.2022.05.014

16. Evaluation of the membrane damage mechanism of thymol against Bacillus cereus and its application in the preservation of skim milk

Author:
Xuyang Wang; Lu Tian; Jiapeng Fu; Sichen Liao; Siqi Yang; Xinyi Jia; Guoli Gong
Source:
Food control 2022 v.131 pp. 108435
ISSN:
0956-7135
Subject:
Bacillus cereus; adenosine triphosphate; cold storage; fluorescence emission spectroscopy; food additives; food safety; membrane potential; minimum inhibitory concentration; pH; skim milk; thymol
Abstract:
... The goal of this study was to elucidate the mechanism by which thymol caused membrane damages in Bacillus cereus cells and the feasibility of its application in the preservation of skim milk. The minimum inhibitory concentration (MIC) of thymol was determined using the broth microdilution method. The membrane potentials, intracellular adenosine triphosphate (ATP) concentrations, and pH gradients a ...
DOI:
10.1016/j.foodcont.2021.108435

17. Exercise and Urtica Dioica extract ameliorate mitochondrial function and the expression of cardiac muscle Nuclear Respiratory Factor 2 and Peroxisome proliferator-activated receptor Gamma Coactivator 1-alpha in STZ-induced diabetic rats

Author:
Seyyedeh Masoumeh Seyydi; Asghar Tofighi; Masoud Rahmati; Javad Tolouei Azar
Source:
Gene 2022 v.822 pp. 146351
ISSN:
0378-1119
Subject:
Urtica dioica; adenosine triphosphate; biogenesis; bioluminescence; cardiac output; citrate (si)-synthase; diabetes mellitus; exercise; genes; males; mitochondria; myocardium; peroxisome proliferator-activated receptor gamma; rats
Abstract:
... Diabetes mellitus can affect and disrupt the levels of PGC1α and NRF2 proteins in the mitochondrial biogenesis pathway. Considering the anti-diabetic properties of Urtica Dioica extract and exercise, this study aimed to investigate the beneficial effects of Urtica Dioica extract and endurance activity on PGC1α and NRF2 protein levels in the streptozotocin-induced diabetic rat heart tissue. 58 male ...
DOI:
10.1016/j.gene.2022.146351

18. Facile preparation of anti-biofouling reverse osmosis membrane embedded with polydopamine-nano copper functionality: Performance and mechanism

Author:
Caihong Liu; Ziyue Wang; Qiang He; Jennifer Jackson; Andreia F. Faria; Wenjuan Zhang; Dan Song; Jun Ma; Zhiqiang Sun
Source:
Journal of membrane science 2022 v.658 pp. 120721
ISSN:
0376-7388
Subject:
Escherichia coli; adenosine triphosphate; adhesion; adsorption; biofouling; bovine serum albumin; cell viability; copper nanoparticles; humic acids; hydrophilicity; lipopolysaccharides; plankton; reverse osmosis; thin film composite membranes; toxicity
Abstract:
... In this study, we conducted a facile membrane modification process by mild electroless deposition of copper nanoparticles (CuNPs) integrating polydopamine (PDA) coating to combat biofouling of thin-film composite (TFC) reverse osmosis (RO) membranes. Various experimental tests and characterization techniques have been applied to reveal the anti-biofouling performance and underlying mechanism of pr ...
DOI:
10.1016/j.memsci.2022.120721

19. Glucagon-like peptide-1 receptor activation by liraglutide promotes breast cancer through NOX4/ROS/VEGF pathway

Author:
Zhan-zhao Liu; Xian-xian Duan; Meng-ci Yuan; Jing Yu; Xiao Hu; Xiao Han; Lan Lan; Bo-wei Liu; Yue Wang; Jun-fang Qin
Source:
Life sciences 2022 v.294 pp. 120370
ISSN:
0024-3205
Subject:
NAD(P)H oxidase (H2O2-forming); Western blotting; adenosine triphosphate; breast neoplasms; cell proliferation; diabetes; flow cytometry; glucagon-like peptide 1; humans; immunohistochemistry; mice; phenotype; quantitative polymerase chain reaction; reactive oxygen species; risk; signal transduction; toxicology; vascular endothelial growth factors
Abstract:
... Scientific evidence imply the strong correlation between diabetes and breast cancer. Glucagon-like peptide-1 (GLP-1) and its analogue liraglutide, have been widely used for diabetes treatment. However, the role of GLP-1 receptor (GLP-1R) in breast cancer requires further elucidation. This study aimed to investigate the risk and the molecular mechanisms of liraglutide using in breast cancer. Quanti ...
DOI:
10.1016/j.lfs.2022.120370

20. High O2/N2 controlled atmosphere accelerates postharvest ripening of ‘Hayward’ kiwifruit

Author:
Jiaxin Chai; Yutang Wang; Yanfei Liu; Zimin Gu; Zhande Liu
Source:
Scientia horticulturae 2022 v.300 pp. 111073
ISSN:
0304-4238
Subject:
Actinidia deliciosa; adenosine diphosphate; adenosine monophosphate; adenosine triphosphate; catalase; cell respiration; color; firmness; fruit quality; fruits; kiwifruit; oxygen; peroxidase; quantitative polymerase chain reaction; titratable acidity; volatile organic compounds
Abstract:
... Kiwifruit (Actinidia deliciosa cv. Hayward) was exposed to high O₂/N₂ controlled atmosphere (30 % O₂ + 70 % N₂) for 7 d at 23 ± 1 °C to evaluate the effects on postharvest ripening and fruit quality. The treated fruit exhibited a dramatic increase in soluble solids content (SSC) and a rapid decrease in firmness and titratable acidity (TA), accompanied by a noticeable change in flesh color and vola ...
DOI:
10.1016/j.scienta.2022.111073