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- Suyama, Masaki, et al. Show all 10 Authors
- Tetrahedron 2018 v.74 no.9 pp. 962-969
- adenosine triphosphate; benzene; carbon; chemical reactions; enzymes; mitochondria; moieties
- ... Bongkrekic acid (BKA) is a strong inhibitor of adenine nucleotide translocase (ANT), inducing inhibition of adenosine triphosphate synthesis. We designed and synthesized simplified benzene-ring-containing BKA analogs. The key reaction is the one-pot double Sonogashira reaction, which forms the main skeleton. The analogs were efficiently synthesized in 8–10 longest linear sequence steps. This synth ...