Author: "Eyer, Joel" / Subject: adults

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Author:: Eyer, Joel, et al. ; Carradori, Dario; Saulnier, Patrick; Préat, Véronique; des Rieux, Anne; Show all 5 Authors
Source:: Journal of Controlled Release 2016 v.238 pp. 253-262
ISSN:: 0168-3659
Subject:: adults; brain; chemical elements; drug delivery systems; lipids; nanocapsules; neurodegenerative diseases; neurons; rats; spinal cord; stem cells
Abstract:: ... The replacement of injured neurons by the selective stimulation of neural stem cells in situ represents a potential therapeutic strategy for the treatment of neurodegenerative diseases. The peptide NFL-TBS.40-63 showed specific interactions towards neural stem cells of the subventricular zone. The aim of our work was to produce a NFL-based drug delivery system able to target neural stem cells thro ...
DOI:: 10.1016/j.jconrel.2016.08.006
: http://dx.doi.org/10.1016/j.jconrel.2016.08.006

Author:: Eyer, Joel, et al. ; Carradori, Dario; Saulnier, Patrick; Préat, Véronique; des Rieux, Anne; Show all 5 Authors
Source:: Biomaterials 2017 v.123 pp. 77-91
ISSN:: 0142-9612
Subject:: adults; cell differentiation; central nervous system; drug delivery systems; image analysis; nanomedicine; neurodegenerative diseases; neurogenesis; neurons; stem cells
Abstract:: ... The discovery of adult neurogenesis drastically changed the therapeutic approaches of central nervous system regenerative medicine. The stimulation of this physiologic process can increase memory and motor performances in patients affected by neurodegenerative diseases. Neural stem cells contribute to the neurogenesis process through their differentiation into specialized neuronal cells. In this r ...
DOI:: 10.1016/j.biomaterials.2017.01.032
: http://dx.doi.org/10.1016/j.biomaterials.2017.01.032