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- Kim, Junhyong, et al. Show all 8 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2011 v.108 no.29 pp. 11918-11923
- adults; astrocytes; cardiomyocytes; fibroblasts; gene overexpression; models; phenotype; transcription factors; transcriptome
- ... We show that the transfer of the adult ventricular myocyte (AVM) transcriptome into either a fibroblast or an astrocyte converts the host cell into a cardiomyocyte. Transcriptome-effected cardiomyocytes (tCardiomyocytes) display morphologies, immunocytochemical properties, and expression profiles of postnatal cardiomyocytes. Cell morphology analysis shows that tCardiomyoctes are elongated and have ...
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