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- Bott, Kirsten N., et al. Show all 7 Authors
- Biochemical and biophysical research communications 2019
- adverse effects; blood serum; bone formation; glycogen synthase kinases; ligands; lithium; mice; signal transduction; tau-protein kinase
- ... Lithium, a well-known inhibitor of glycogen synthase kinase-3β (GSK3β), can improve bone formation by activating the Wnt/β-catenin signalling pathway. However, most studies have used higher doses of lithium, which potentially have adverse effects. Herein, we report that low dose lithium supplementation (10 mg/kg/d for 6 weeks) in mice results in a serum lithium concentration of 0.02 mM significant ...