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- Lee, Seongsoo, et al. Show all 6 Authors
- Biochemical and biophysical research communications 2019 v.513 no.4 pp. 925-932
- Alzheimer disease; Parkinson disease; amyotrophic lateral sclerosis; autophagy; death; enzymes; neurons; protein aggregates; therapeutics; toxicity
- ... The most prominent hallmarks of many neurodegenerative diseases are the accumulation of misfolded protein aggregates and the death of certain neuronal populations. Autophagy is the major intracellular mechanism that degrades protein aggregates and damaged cellular components. Many studies have reported that the dysfunction of autophagy is associated with several neurodegenerative diseases, such as ...