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- Zhang, Wei Fen, et al. Show all 6 Authors
- Drying technology 2015 v.33 no.1 pp. 55-65
- animal disease models; animal proteins; anti-inflammatory activity; asthma; encapsulation; enzyme-linked immunosorbent assay; goblet cells; histopathology; immunohistochemistry; interleukin-4; patient compliance; scanning electron microscopes; spectroscopy; spray drying; theophylline; therapeutics; transcription factor NF-kappa B; tumor necrosis factor-alpha; water content
- ... Theophylline has been reported to have considerable pharmacological activity for asthma, which is partly mediated by the anti-inflammatory effects of theophylline. Nevertheless, the wide application of theophylline was hampered due to its rapid metabolization and the poor patient compliance. Microspheres can be applied as targeted and sustained drug-release carriers. The purposes of the present st ...