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You searched for: Subject term antioxidant activity Remove constraint Subject term: antioxidant activity Subject term antineoplastic activity Remove constraint Subject term: antineoplastic activity
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1. In vitro antioxidative and anticancer activities of tea glycoprotein in green tea

Author:
Nie, Shaoping; Xie, Mingyong; Zhou, Peng; Cao, Shuwen
Source:
European food research & technology 2007 v.224 no.4 pp. 437-442
ISSN:
1438-2377
Subject:
2,2-diphenyl-1-picrylhydrazyl; antineoplastic activity; antioxidant activity; autoxidation; beta-carotene; colorectal neoplasms; decolorization; food research; gel chromatography; glycoproteins; green tea; linoleic acid; pyrogallol
Abstract:
... In this paper, the antioxidative and anticancer activities of tea glycoprotein (TGP) in green tea were studied. TGP was extracted from coarse old green tea and purified by Sephadex G-100 gel filtration, and its purity was determined by high performance gel permeation chromatography (HPGPC). The antioxidative activity of the TGP was evaluated by determining the change of the values of the heat-indu ...
DOI:
10.1007/s00217-006-0324-y

2. The Natural Products in Protection against the most Important Pathological Changes in Human Metabolism

Author:
M. Votruba; M. Vecka; L. Prokeš; B. Jurášková
Source:
Czech Journal of Food Sciences v.27 no.Special Issue 1 pp. S31
ISSN:
1805-9317
Subject:
Helicobacter pylori; Vaccinium macrocarpon; adhesion; antineoplastic activity; antioxidant activity; arachidonic acid; bacterial adhesion; carcinogenesis; cell growth; cell proliferation; color; epoxides; flavonoids; humans; inflammation; inositols; leukotrienes; metabolism; phenotype; phospholipase A2; phospholipids; prostaglandins; signal transduction; stomach; stomach neoplasms; urinary tract
Abstract:
... Inflammation in joint: The liberation of phospholipids from cell membranes represents the first step of inflammation cascade. By action of phospholipase A2 is split of the arachidonic acid. Free arachidonic acid is than metabolised by two enzymes: 5-lipooxygenase and 2-cyclooxygenase to generate the group of prostanoids and leukotrienes which are the first active proinflammation compounds, ...
DOI:
10.17221/1095-cjfs

3. Antitumor activity of Sansevieria roxburghiana rhizome against Ehrlich ascites carcinoma in mice

Author:
Haldar, Pallab Kanti; Kar, Biswakanth; Bala, Asis; Bhattacharya, Sanjib; Mazumder, Upal Kanti
Source:
Pharmaceutical biology 2010 v.48 no.12 pp. 1337-1343
ISSN:
1388-0209
Subject:
Sansevieria; antineoplastic activity; antioxidant activity; antioxidants; ascites; blood chemistry; body weight; carcinoma; catalase; cell viability; glutathione; hematocrit; hosts; lipid peroxidation; longevity; mice; neoplasm cells; perennials; rhizomes; superoxide dismutase
Abstract:
... Context: Sansevieria roxburghiana Schult. & Schult. f. (Agavaceae) is a herbaceous perennial plant traditionally used for coughs, rheumatism; as an expectorant, febrifuge, purgative, and tonic. Objective: To evaluate the hydroalcoholic extract of S. roxburghiana rhizome (HASR) for antitumor activity against Ehrlich ascites carcinoma (EAC) in Swiss albino mice. Methods: Twenty-Four hours after intr ...
DOI:
10.3109/13880201003792592

4. Antitumoral and antioxidant effect of essential oils and in vitro antioxidant properties of essential oils and aqueous extracts from Salvia pisidica

Author:
Aysun Ozkan; Ayse Erdogan; Munevver Sokmen; Saadet Tugrulay; Orhan Unal
Source:
Biologia 2010 v.65 no.6 pp. 990-996
ISSN:
1336-9563
Subject:
Salvia; antineoplastic activity; antioxidant activity; cytotoxicity; essential oils; free radical scavengers; hydrogen peroxide; hydroxyl radicals; inhibitory concentration 50; linoleic acid; neoplasm cells; neoplasms; oils; oxidants; oxidation; protective effect
Abstract:
... The aim of the work was to investigate antitumoral effect of essential oils on cancer cells and their possible protective (antioxidant) effects against hydrogen peroxide-induced cytotoxicity. Also, in vitro antioxidant properties of essential oils and aqueous extracts from wild form and cultivated form of Salvia pisidica were compared.We found out that essential oils from wild form (IC50 128, and ...
DOI:
10.2478/s11756-010-0108-5

5. Chitooligosaccharides Protect Human Embryonic Hepatocytes Against Oxidative Stress Induced by Hydrogen Peroxide

Author:
Xu, Qingsong; Ma, Pan; Yu, Weiting; Tan, Chengyu; Liu, Hongtao; Xiong, Chuannan; Qiao, Ying; Du, Yuguang
Source:
Marine biotechnology 2010 v.12 no.3 pp. 292-298
ISSN:
1436-2228
Subject:
2,2-diphenyl-1-picrylhydrazyl; NAD ADP-ribosyltransferase; antineoplastic activity; antioxidant activity; apoptosis; cell viability; chitooligosaccharides; confocal laser scanning microscopy; free radical scavengers; hepatocytes; hepatoprotective effect; humans; hydrogen peroxide; liver; oxidative stress; pro-apoptotic proteins
Abstract:
... Chitooligosaccharides (COS) has many biological activities, such as antitumor activity and hepatoprotective effect. Herein, we investigated the protective effect of COS against hydrogen peroxide (H₂O₂)-induced oxidative stress on human embryonic hepatocytes (L02 cells) and its scavenging activity against the 1,1-diphenyl-2-picrylhydrazyl radical in vitro. The results showed that the lost cell viab ...
DOI:
10.1007/s10126-009-9222-1
PubMed:
19690919

6. Current advances in Phellinus sensu lato: medicinal species, functions, metabolites and mechanisms

Author:
Dai, Yu-Cheng; Zhou, Li-Wei; Cui, Bao-Kai; Chen, Yan-Qiu; Decock, Cony
Source:
Applied microbiology and biotechnology 2010 v.87 no.5 pp. 1587-1593
ISSN:
0175-7598
Subject:
Phellinus; antineoplastic activity; antioxidant activity; apoptosis; diabetes; fermentation; immune response; medicinal fungi; metabolites; metastasis; polyphenols; polysaccharides; septic shock; taxonomy
Abstract:
... Twenty-six species of Phellinus sensu lato, reported as medicinal mushrooms, are enumerated in this review. The species' names were checked and revised according to contemporary taxonomy and the latest version of the International Code of Botanical Nomenclature (Vienna Code); two misapplied names of Phellinus baumii Pilát and Phellinus himalayensis Y.C. Dai in previous reports are also discussed. ...
DOI:
10.1007/s00253-010-2711-3
PubMed:
20549200

7. Free radical scavenging, angiotensin I-converting enzyme (ACE) inhibitory, and in vitro anticancer activities of ramie (Boehmeria nivea) leaves extracts

Author:
Jin Woo Nho; In Guk Hwang; Hyun Young Kim; Youn Ri Lee; Koan Sik Woo; Bang Yeon Hwang; Seong Jun Chang; Junsoo Lee; Heon Sang Jeong
Source:
Food science and biotechnology 2010 v.19 no.2 pp. 383-390
ISSN:
1226-7708
Subject:
2,2-diphenyl-1-picrylhydrazyl; Boehmeria nivea; antineoplastic activity; antioxidant activity; chloroform; ethyl acetate; free radical scavengers; functional foods; hexane; hydroxyl radicals; inhibitory concentration 50; leaf extracts; leaves; medicine; peptidyl-dipeptidase A; ramie; solvents; superoxide anion
Abstract:
... The objectives of this study were to evaluate the antioxidant activity, angiotensin I-converting enzyme (ACE) inhibitory activity, and anticancer activity of ramie (Boehmeria nivea) leaves (RL). The RL was extracted with 70%(v/v) ethanol (RLE) and fractionated with the solvents of hexane, chloroform, ethylacetate, and aqueous. The ethylacetate fraction (EF) contained the highest phenolic contents ...
DOI:
10.1007/s10068-010-0054-6

8. Algae as promising organisms for environment and health

Author:
Emad Shalaby
Source:
Plant signaling & behavior 2011 v.6 no.9 pp. 1338-1350
ISSN:
1559-2324
Subject:
algae; antineoplastic activity; antioxidant activity; bioremediation; carotenoids; developmental stages; organic fertilizers; phenolic compounds; phycobiliprotein; pigments; polysaccharides; secondary metabolites; unsaturated fatty acids
Abstract:
... Algae like other plants produce a variety of remarkable compounds collectivity refereed to as secondary metabolites they are synthesized by these organisms at the end of the growth phase and/or due to metabolic alterations induced by environmental stress conditions. Carotenoids, phenolic compounds, phycobiliprotein pigments, polysaccharides and unsaturated fatty acids are same of the algal natural ...
DOI:
10.4161/psb.6.9.16779
PubMed:
21862867
PubMed Central:
PMC3258063

9. Anticancer effects of fraction isolated from fruiting bodies of Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilat (Aphyllophoromycetideae): In vitro studies

Author:
Lemieszek, Marta Kinga; Langner, Ewa; Kaczor, Jozef; Kandefer-Szerszen, Martyna; Sanecka, Bozena; Mazurkiewicz, Witold; Rzeski, Wojciech
Source:
International journal of medicinal mushrooms 2011 v.13 no.2 pp. 131-143
ISSN:
1521-9437
Subject:
Inonotus obliquus; adenocarcinoma; animal models; antineoplastic activity; antineoplastic agents; antioxidant activity; aorta; astrocytes; cattle; cell culture; cell movement; cell proliferation; colon; cytotoxicity; death; digestive system diseases; endothelial cells; enzyme-linked immunosorbent assay; fibroblasts; fruiting bodies; health promotion; heart; hepatocytes; humans; in vitro studies; liver; lung neoplasms; medicinal fungi; mice; mushrooms; neoplasm cells; neurons; oligodendroglia; rats; staining; toxicity testing; traditional medicine; viability; Poland; Russia
Abstract:
... The medicinal mushroom Chaga, Inonotus obliquus (Pers.:Fr.) Pilat (Hymenochaetaceae), has been used in folk medicine in Russia, Poland, and most of the Baltic countries, as a cleansing and disinfecting measure, and as decoctions for stomach diseases, intestinal worms, liver and heart ailments, and cancer treatment. Many reports have been published concerning the health promoting functions of this ...
DOI:
10.1615/IntJMedMushr.v13.i2.50

10. Antioxidant and cytotoxic activity of polyphenolic compounds isolated from the leaves of Leucenia leucocephala

Author:
Haggag, Eman G.; Kamal, Amel M.; Abdelhady, Mohamed I.S.; El-Sayed, Mortada M.; El-Wakil, Eman A.; Abd-El-hamed, Sayed S.
Source:
Pharmaceutical biology 2011 v.49 no.11 pp. 1103-1113
ISSN:
1388-0209
Subject:
Fabaceae; active ingredients; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apigenin; chemical structure; chromatography; cytotoxicity; glycosides; health services; hepatoma; inhibitory concentration 50; leaf extracts; leaves; luteolin; methanol; myricetin; nuclear magnetic resonance spectroscopy; polyphenols; Egypt
Abstract:
... Context: Cancer is a serious clinical problem to the health care system. Anticancer drugs have been extracted from plants containing phenolic compounds. Leucenia species (Fabaceae) contain a variety of bioactive components of numerous biological and pharmacological properties. Objective: This study explored the constitutive polyphenols of Leucenia leucocephala Lam. growing in Egypt and evaluated t ...
DOI:
10.3109/13880209.2011.568623

11. Antioxidant capacity of hesperidin from Citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines

Author:
Al-Ashaal, Hanan A.; El-Sheltawy, Shakinaz T.
Source:
Pharmaceutical biology 2011 v.49 no.3 pp. 276-282
ISSN:
1388-0209
Subject:
Citrus sinensis; antineoplastic activity; antioxidant activity; antioxidants; antiviral properties; cervix; chemoprevention; cytotoxicity; electron paramagnetic resonance spectroscopy; hesperidin; high performance liquid chromatography; humans; inhibitory concentration 50; larynx; liver; methanol; neoplasm cells; orange peels; pharmaceutical industry; spectral analysis; thin layer chromatography
Abstract:
... Context: Hesperidin is a flavonoid that has various pharmacological activities including anti-inflammatory, antimicrobial and antiviral activities. Objective: The aim of the study is the isolation of hesperidin from the peel of Citrus sinensis L. (Rutaceae), and the evaluation of its antioxidant capacity and cytotoxicity against different human carcinoma cell lines. Materials and methods: In the p ...
DOI:
10.3109/13880209.2010.509734

12. Antioxidant, antimicrobial and anticancer activity of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis

Author:
Branislav R Ranković; Marijana M Kosanić; Tatjana P Stanojković
Source:
BMC complementary and alternative medicine 2011 v.11 no.1 pp. 97
ISSN:
1472-6882
Subject:
Cladonia; Lecanora; acetone; alternative medicine; anti-infective agents; antimicrobial properties; antineoplastic activity; antineoplastic agents; antioxidant activity; bacteria; colorectal neoplasms; flavonoids; free radical scavengers; fungi; humans; inhibitory concentration 50; lichens; melanoma; minimum inhibitory concentration; phenolic compounds; plant diseases and disorders
Abstract:
... BACKGROUND: The aim of this study is to investigate in vitro antioxidant, antimicrobial and anticancer activity of the acetone extracts of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis. METHODS: Antioxidant activity was evaluated by five separate methods: free radical scavenging, superoxide anion radical scavenging, reducing power, determination of total phenolic compounds and d ...
DOI:
10.1186/1472-6882-11-97
PubMed:
22013953
PubMed Central:
PMC3224239

13. Antitumor efficacy and amelioration of oxidative stress by Trichosanthes dioica root against Ehrlich ascites carcinoma in mice

Author:
Bhattacharya, Sanjib; Prasanna, Angelene; Majumdar, Piyali; Kumar, R.B. Suresh; Haldar, Pallab K.
Source:
Pharmaceutical biology 2011 v.49 no.9 pp. 927-935
ISSN:
1388-0209
Subject:
Trichosanthes dioica; antineoplastic activity; antioxidant activity; antioxidants; ascites; body weight; carcinoma; catalase; cell viability; dose response; glutathione; glutathione transferase; hematocrit; hosts; lipid peroxidation; liver; longevity; mice; neoplasm cells; oxidative stress; superoxide dismutase; India
Abstract:
... Context: Trichosanthes dioica Roxb. (Cucurbitaceae) is a dioecious climber, traditionally used in India for several medicinal purposes. Objective: The present study assessed the hydroalcoholic extract of T. dioica root (TDA) for antitumor effect and antioxidant influence against Ehrlich ascites carcinoma (EAC) in Swiss albino mice. Methods: Twenty four hours after intraperitoneal inoculation of tu ...
DOI:
10.3109/13880209.2011.557080

14. RETRACTION: In vitro antioxidant and anticancer activity of young Zingiber officinale against human breast carcinoma cell lines

Author:
Shahedur Rahman; Faizus Salehin; Asif Iqbal
Source:
BMC complementary and alternative medicine 2011 v.11 no.1 pp. 76
ISSN:
1472-6882
Subject:
Zingiber officinale; alternative medicine; antineoplastic activity; antioxidant activity; antioxidants; breast neoplasms; bromides; carbon dioxide; crops; flavonoids; ginger; humans; inhibitory concentration 50; medicinal plants; neoplasm cells; reversed-phase high performance liquid chromatography; rhizomes; thiobarbituric acid; Bangladesh
Abstract:
... BACKGROUND: Ginger is one of the most important spice crops and traditionally has been used as medicinal plant in Bangladesh. The present work is aimed to find out antioxidant and anticancer activities of two Bangladeshi ginger varieties (Fulbaria and Syedpuri) at young age grown under ambient (400 μmol/mol) and elevated (800 μmol/mol) CO₂ concentrations against two human breast cancer cell lines ...
DOI:
10.1186/1472-6882-11-76
PubMed:
21933433
PubMed Central:
PMC3203256

15. Chemical composition of three Parmelia lichens and antioxidant, antimicrobial and cytotoxic activities of some their major metabolites

Author:
Nedeljko Manojlović; Branislav Ranković; Marijana Kosanić; Perica Vasiljević; Tatjana Stanojković
Source:
Phytomedicine 2012 v.19 no.13 pp. 1166-1172
ISSN:
0944-7113
Subject:
Parmelia; acetone; acids; anti-infective agents; anti-infective properties; antineoplastic activity; antioxidant activity; chemical composition; colorectal neoplasms; cytotoxicity; free radical scavengers; high performance liquid chromatography; humans; inhibitory concentration 50; lichens; melanoma; metabolites; minimum inhibitory concentration; phenolic compounds; superoxide anion
Abstract:
... The aim of this study is to investigate chemical composition of acetone extracts of the lichens Parmelia caperata, P. saxatilis and P. sulcata and antioxidant, antimicrobial and anticancer activities of some their major metabolites. The phytochemical analysis of acetone extracts of three Parmelia lichens were determined by HPLC-UV method. The predominant phenolic compounds in these extracts were p ...
DOI:
10.1016/j.phymed.2012.07.012

16. Medicinal halophytes: potent source of health promoting biomolecules with medical, nutraceutical and food applications

Author:
Riadh Ksouri; Wided Megdiche Ksouri; Inès Jallali; Ahmed Debez; Christian Magné; Isoda Hiroko; Chedly Abdelly
Source:
Critical reviews in biotechnology 2012 v.32 no.4 pp. 289-326
ISSN:
1549-7801
Subject:
analytical methods; antineoplastic activity; antioxidant activity; atherosclerosis; bioactive compounds; carotenoids; coasts; deserts; essential oils; functional foods; glycosides; habitats; halophytes; health promotion; industry; inflammation; neoplasms; phenolic compounds; plant growth; polysaccharides; polyunsaturated fatty acids; proteins; salinity; salt marsh plants; salt marshes; salt tolerance; secondary metabolites; steppes; sterols; traditional medicine; traditional technology; vitamins
Abstract:
... Salt-tolerant plants grow in a wide variety of saline habitats, from coastal regions, salt marshes and mudflats to inland deserts, salt flats and steppes. Halophytes living in these extreme environments have to deal with frequent changes in salinity level. This can be done by developing adaptive responses including the synthesis of several bioactive molecules. Consequently, several salt marsh plan ...
DOI:
10.3109/07388551.2011.630647

17. Novel physiological properties of ethanol extracts from Eremurus chinensis Fedtsch. roots: in vitro antioxidant and anticancer activities

Author:
Haifang Xiao; Yutang Wang; Qisen Xiang; Chunxia Xiao; Li Yuan; Zhigang Liu; Xuebo Liu
Source:
Food & function 2012 v.3 no.12 pp. 1310-1318
ISSN:
2042-650X
Subject:
2,2-diphenyl-1-picrylhydrazyl; DNA; Eremurus; Western blotting; antineoplastic activity; antioxidant activity; apoptosis; caspase-3; copper; cytochrome c; ethanol; free radicals; functional properties; human cell lines; hydrogen peroxide; lipids; roots; signal transduction; toxicity testing; China
Abstract:
... Eremurus chinensis Fedtch. (ECF) with nutritious roots, belonging to the genus of Eremurus, is a special species grown in China. However, the functional properties of ECF roots have not been intensely investigated. The antioxidant and anticancer effects of ethanol extracts from E. chinensis Fedtch. roots (ECFE) were evaluated in the present study. ECFE exhibited high radical-scavenging activities ...
DOI:
10.1039/c2fo30152k

18. Phytochemical Composition and Antioxidant Potential of Ruta graveolens L. In Vitro Culture Lines

Author:
Diwan Renuka; Shinde Amit; Malpathak Nutan; University Grants Commission
Source:
Journal of botany 2012 v.2012 pp. -
ISSN:
2090-0120
Subject:
2,2-diphenyl-1-picrylhydrazyl; Ruta graveolens; antineoplastic activity; antioxidant activity; free radical scavengers; lymphoma; medicinal plants; medicine; nitric oxide; plant extracts; psoriasis
Abstract:
... Ruta graveolens L. is a medicinal plant used in traditional systems of medicine for treatment of psoriasis, vitiligo, leucoderma, and lymphomas with well-known anti-inflammatory and anticancer properties. Therefore antioxidant potential of R. graveolens (in planta and in vitro) was investigated. As antioxidants present in plant extracts are multifunctional, their activity and mechanism depends on ...
DOI:
10.1155/2012/685427

19. Piper betle shows antioxidant activities, inhibits MCF-7 cell proliferation and increases activities of catalase and superoxide dismutase

Author:
Noor Nazirahanie Abrahim; M S Kanthimathi; Azlina Abdul-Aziz
Source:
BMC complementary and alternative medicine 2012 v.12 no.1 pp. 220
ISSN:
1472-6882
Subject:
2,2-diphenyl-1-picrylhydrazyl; Piper betle; alternative medicine; antineoplastic activity; antioxidant activity; breast neoplasms; catalase; catechin; cell proliferation; colorimetry; drug therapy; enzyme activity; ethyl acetate; free radicals; glutathione peroxidase; hexane; high performance liquid chromatography; leaves; medicinal plants; methanol; nitric oxide; plant extracts; quercetin; solvents; superoxide anion; superoxide dismutase
Abstract:
... BACKGROUND: Breast cancer is the most common form of cancer and the focus on finding chemotherapeutic agents have recently shifted to natural products. Piper betle is a medicinal plant with various biological activities. However, not much data is available on the anti-cancer effects of P. betle on breast cancer. Due to the current interest in the potential effects of antioxidants from natural prod ...
DOI:
10.1186/1472-6882-12-220
PubMed:
23153283
PubMed Central:
PMC3533855

20. Antioxidant activity and anticancer effect of Vitex agnus-castus L. (Verbenaceae) seed extracts on MCF–7 breast cancer cells

Author:
Özlem Sultan Aslantürk; Tülay Aşkın Çelik
Source:
Caryologia 2013 v.66 no.3 pp. 257-267
ISSN:
2165-5391
Subject:
DNA; Verbenaceae; Vitex agnus-castus; antineoplastic activity; antioxidant activity; antioxidants; apoptosis; breast neoplasms; cytotoxicity; ethyl acetate; ethyl ether; humans; iodides; methanol; neoplasm cells; petroleum; phenolic compounds; seed extracts; seeds; staining
Abstract:
... Aim : The aim of this study was to investigate the in vitro antioxidant and anticancer activities of diethyl ether, petroleum ether, ethyl acetate, methanol and water (infusion and decoction) extracts from Vitex agnus-castus L. (Verbenaceae) seeds. Materials and methods : Antioxidant activities of crude extracts from V. agnus-castus L. seeds were evaluated by 1,1-diphenyl-2-picryl-hydrazyl radical ...
DOI:
10.1080/00087114.2013.850797

21. Antioxidant and anti-tumor activity of a polysaccharide from freshwater clam, Corbicula fluminea

Author:
Ningbo Liao; Shiguo Chen; Xingqian Ye; Jianjun Zhong; Nian Wu; Shilei Dong; Bo Yang; Donghong Liu
Source:
Food & function 2013 v.4 no.4 pp. 539-548
ISSN:
2042-650X
Subject:
Corbicula fluminea; antineoplastic activity; antioxidant activity; antioxidants; aquatic organisms; bioactive compounds; clams; dose response; freshwater; fucose; functional foods; galactose; glucosamine; glucose; humans; ingredients; molecular weight; neoplasm cells; nutritive value; ovarian neoplasms; polysaccharides; stomach neoplasms; sulfates; China
Abstract:
... The fresh water clam Corbicula fluminea is currently one of the most economically important aquatic species in China because of its nutritional value and pharmacological activity. In order to explore the potential of C. fluminea as a natural resource of bioactive compounds, a papain-released polysaccharide designated CFPS-2 was isolated. Chemical composition analysis indicated that CFPS-2 containe ...
DOI:
10.1039/c2fo30178d

22. Comparative studies on the constituents, antioxidant and anticancer activities of extracts from different varieties of corn silk

Author:
Jingge Tian; Haixia Chen; Shuhan Chen; Lisha Xing; Yanwei Wang; Jia Wang
Source:
Food & function 2013 v.4 no.10 pp. 1526-1534
ISSN:
2042-650X
Subject:
2,2-diphenyl-1-picrylhydrazyl; antineoplastic activity; antioxidant activity; antioxidants; breast neoplasms; comparative study; cytotoxicity; formononetin; high performance liquid chromatography; in vitro studies; lipid peroxidation; neoplasm cells; prostatic neoplasms; styles (flowers)
Abstract:
... The purpose of this study was to analyze the influence of varieties on the constituents, antioxidant and anticancer activities of corn silk. The contents of total phenolic and flavonoids and individual flavonoids in six corn silk varieties (Denghai6702, Delinong988, Tunyu808, Zhongdan909, Liangyu208, Jingke968) were comparatively analyzed by colourimetric methods, high performance liquid chromatog ...
DOI:
10.1039/c3fo60171d

23. Effect of co-administration of CoQ10-loaded nanoparticles on the efficacy and cardiotoxicity of doxorubicin-loaded nanoparticles

Author:
Nitin K. Swarnakar; Kaushik Thanki; Sanyog Jain
Source:
RSC advances 2013 v.3 no.34 pp. 14671-14685
ISSN:
2046-2069
Subject:
antineoplastic activity; antioxidant activity; cardiotoxicity; cell culture; coenzyme Q10; cytotoxicity; drugs; histopathology; human cell lines; lysosomes; mitochondria; nanoparticles; reactive oxygen species; synergism; therapeutics
Abstract:
... The present study investigates the effects of the antioxidant and anticancer properties of CoQ10-NPs on the efficacy and toxicity of Dox. Cell culture experiments revealed a significantly higher cellular uptake of Dox- and CoQ10-NPs in MCF-7 cells, as compared to their free drug counterparts. Further, intracellular tracking demonstrated preferential localization of Dox-NPs in the vicinity of nucle ...
DOI:
10.1039/c3ra41107a

24. Rutabaga (Brassica napus L. var. napobrassica) Seeds, Roots, and Sprouts: A Novel Kind of Food with Antioxidant Properties and Proapoptotic Potential in Hep G2 Hepatoma Cell Line

Author:
Pasko Pawel; Bukowska-Strakova Karolina; Gdula-Argasinska Joanna; Tyszka-Czochara Malgorzata
Source:
Journal of medicinal food 2013 v.16 no.8 pp. 749-759
ISSN:
1557-7600
Subject:
Brassica napus; Chinese hamsters; animal ovaries; antineoplastic activity; antioxidant activity; antioxidants; apoptosis; bioassays; cell membranes; cytotoxicity; flavonoids; functional foods; hepatoma; human cell lines; humans; in vitro studies; luminescence; methanol; neoplasm cells; nutrient content; polyphenols; roots; seeds; vegetables; Europe; North America
Abstract:
... Although rutabaga (Brassica napus L. var. napobrassica) is a popular crop, especially in North Europe and North America, its sprouts are a new kind of vegetable. Rutabaga roots, and particularly sprouts, have not been investigated so far for antioxidant and anticancer effect on human tumor cells (Hep G2). Therefore, in vitro tests were conducted to find out whether rutabaga seeds, roots, and sprou ...
DOI:
10.1089/jmf.2012.0250

25. Anti-Cancer and Immunostimulatory Activity of Chromones and Other Constituents from Cassia petersiana

Author:
Amira M. Gamal-Eldeen; Pierre C. Djemgou; Marguérite Tchuendem; Bonaventure T. Ngadjui; Pierre Tane; Hirata Toshifumi
Source:
Zeitschrift für Naturforschung 2014 v.62 no.5-6 pp. 331-338
ISSN:
1865-7125
Subject:
2,2-diphenyl-1-picrylhydrazyl; Cassia; T-lymphocytes; anti-inflammatory activity; anti-inflammatory agents; antineoplastic activity; antioxidant activity; antioxidants; benzoic acid; breast neoplasms; cytotoxicity; free radicals; hepatoma; immunostimulants; leaves; macrophages; nitric oxide; nuclear magnetic resonance spectroscopy
Abstract:
... Phytochemical investigation of Cassia petersiana Bolle leaves afforded four new compounds, including two chromone derivatives, 7-acetonyl-5-hydroxy-2-methylchromone (petersinone 1, 1) and 7-(propan-2ʹ-ol-1ʹ-yl)-5-hydroxy-2-methylchromone (petersinone 2, 2), two benzoic acid derivatives, 5-methyl-3-(propan-2ʹ-on-1ʹ-yl) benzoic acid (petersinone 3, 3) and 5-(methoxymethyl)-3-(propan-2ʹ-ol-1ʹ-yl) ben ...
DOI:
10.1515/znc-2007-5-622

26. Anticancer activity of Sargassum wightii Greville on Dalton's ascitic lymphoma

Author:
Ashwini Anjana; K.F.H Nazeer Ahamed; V. Ravichandiran; M. Sumithra; Jayaraman Anbu
Source:
Chinese journal of natural medicines 2014 v.12 no.2 pp. 114-120
ISSN:
1875-5364
Subject:
Oriental traditional medicine; Sargassum wightii; antineoplastic activity; antioxidant activity; body weight; cell lines; cell proliferation; flavonoids; hematologic tests; longevity; lymphoma; mice; neoplasm cells
Abstract:
... Sargassum wightii Greville is a marine brown alga belonging to the Sargassaceae family which has about 200 species. The ethanolic extract of the whole dry plant powder contained numerous phytoconstituents, including flavonoids. The study was focused on the anticancer activity of Sargassum wightii in mice.The ethanolic extract of Sargassum wightii (EESW) at two dose levels was used to examine the a ...
DOI:
10.1016/S1875-5364(14)60018-2

27. Antioxidant and antitumor activities of 4-arylcoumarins and 4-aryl-3,4-dihydrocoumarins

Author:
Keyun Zhang; Weixian Ding; Jie Sun; Bin Zhang; Fujiao Lu; Ren Lai; Yong Zou; Gabriel Yedid
Source:
Biochimie 2014 v.107 pp. 203-210
ISSN:
0300-9084
Subject:
2,2-diphenyl-1-picrylhydrazyl; Galleria mellonella; antineoplastic activity; antioxidant activity; appetite; ascorbic acid; erythrocytes; free radical scavengers; free radicals; hemolysis; larvae; median effective concentration; mortality; nitric oxide; rabbits; structure-activity relationships; toxicity; toxicity testing; viability
Abstract:
... Five 4-arylcoumarins (1c–g) and twelve 3,4-dihydro-4-arylcoumarins (2a–l) were synthesized and tested for antioxidant activity, antitumor activity, toxicity and structure–activity relationships analysis. 4-Arylcoumarins and 3,4-dihydro-4-arylcoumarins that possess two hydroxyl groups in ortho position, such as 1d, 1f, 2a, 2f, 2g and 2h had stronger radical scavenging properties than that of vitami ...
DOI:
10.1016/j.biochi.2014.03.014

28. Antioxidant capacity and antitumor activity of Fructus Kochiae extracts

Author:
J. Wang; L. Yuan; B. Cheng; W. Li; C. Xiao; Y. Wang; X. Liu
Source:
Quality assurance and safety of crops & foods 2014 v.6 no.4 pp. 383-393
ISSN:
1757-837X
Subject:
Bassia scoparia; antineoplastic activity; antioxidant activity; dried fruit; ethanol; food additives; food plants; free radicals; fruits; high performance liquid chromatography; models; neoplasm cells; neoplasms; oxidation; quality control; China
Abstract:
... Fructus Kochiae (dried fruit of Kochia scoparia (L.) Schrad., broom cypress fruit), widely distributed in the northwest of China, has been used as medicinal and edible plant for thousands of years. The antioxidant activities and antitumor effect of aqueous and 50% ethanol Fructus Kochiae extracts were investigated. Furthermore, the content of momordin Ic by HPLC and the antioxidant activity by pro ...
DOI:
10.3920/QAS2012.0218

29. Antitumour and Antioxidant Activity of Some Red Sea Seaweeds in Ehrlich Ascites Carcinoma in vivo

Author:
Hanaa H. Ahmed; Muhammad M. Hegazi; Howaida I. Abd-Allac; Emad F. Eskander; Mona S. Ellithey
Source:
Zeitschrift für Naturforschung 2014 v.66 no.7-8 pp. 367-376
ISSN:
1865-7125
Subject:
Jania; Sargassum; Ulva lactuca; antigens; antineoplastic activity; antioxidant activity; antioxidants; ascites; carbohydrates; carcinoma; carotenoids; chemical constituents of plants; cholesterol; enzymes; halides; intramuscular injection; liver; macroalgae; malondialdehyde; methylene chloride; minerals; neoplasm cells; nitric oxide; oxidants; proteins; screening; Red Sea
Abstract:
... The antitumour activities of extracts from the Red Sea seaweeds Jania rubens, Sargassum subrepandum, and Ulva lactuca were investigated in an in vivo mice model based on intramuscular injection of Ehrlich ascites tumour cells. In parallel, antioxidant activities were measured. Tumour marker levels, liver biochemical parameters, and hepatic oxidant/antioxidant status were measured to prove the anti ...
DOI:
10.1515/znc-2011-7-808

30. Biosynthesis of silver nanoparticles: Elucidation of prospective mechanism and therapeutic potential

Author:
Amit Kumar Mittal; Jayeeta Bhaumik; Sanjay Kumar; Uttam Chand Banerjee
Source:
Journal of colloid and interface science 2014 v.415 pp. 39-47
ISSN:
0021-9797
Subject:
Syzygium cumini; ambient temperature; antineoplastic activity; antioxidant activity; biosynthesis; cell lines; flavonoids; fruit extracts; lymphoma; nanobiotechnology; nanoparticles; nanosilver; neoplasm cells; therapeutics; viability
Abstract:
... The synthesis of silver nanoparticles (AgNPs) was accomplished using Syzygium cumini fruit extract at room temperature. Various techniques were used to characterize the newly synthesized silver nanoparticles and their size was determined to be 10–15nm. Important findings of this study were the identification of biomolecules responsible for the synthesis of silver nanoparticles and elucidate the me ...
DOI:
10.1016/j.jcis.2013.10.018

31. Characterization, antioxidant and antitumor activities of polysaccharides from Salvia miltiorrhiza Bunge

Author:
Yuan-yuan Jiang; Long Wang; Li Zhang; Tao Wang; Lin Yu; Chun-bang Ding; Rui-wu Yang; Xiao-li Wang; Yong-hong Zhou
Source:
International journal of biological macromolecules 2014 v.70 pp. 92-99
ISSN:
0141-8130
Subject:
2,2-diphenyl-1-picrylhydrazyl; Salvia miltiorrhiza; antineoplastic activity; antineoplastic agents; antioxidant activity; breast neoplasms; free radical scavengers; humans; in vitro studies; neoplasm cells; polysaccharides; response surface methodology; temperature; ultrasonic treatment; ultrasonics
Abstract:
... Polysaccharides were extracted from Salvia miltiorrhiza Bunge using response surface methodology (RSM) with ultrasonication. A Box–Behnken design was used to optimize the extraction parameters to maximize the polysaccharide extraction yield. The polysaccharide SMP-U1 was isolated and characterized; then the antioxidant and antiproliferation activities were evaluated in vitro. The modified optimal ...
DOI:
10.1016/j.ijbiomac.2014.06.036

32. Chemical characterization, antioxidant and antitumor activity of sulfated polysaccharide from Sargassum horneri

Author:
Ping Shao; Xiaoxiao Chen; Peilong Sun
Source:
Carbohydrate polymers 2014 v.105 pp. 260-269
ISSN:
0144-8617
Subject:
hydroxyl radicals; molecular weight; sulfates; antineoplastic activity; flow cytometry; chromatography; reverse transcriptase polymerase chain reaction; genes; antioxidant activity; growth retardation; polysaccharides; superoxide anion; Sargassum horneri; interphase
Abstract:
... Three water-soluble polysaccharide fractions (SHP30, SHP60, and SHP80) extracted from the Sargassum horneri were obtained by water extraction and radial flow chromatography. The high-performance gel-permeation chromatography analysis showed that the average molecular weight (Mw) of three polysaccharides were approximately 1.58×103, 1.92×103 and 11.2KDa, respectively. Their in vitro antioxidant act ...
DOI:
10.1016/j.carbpol.2014.01.073

33. Chemical composition and free radical-scavenging, anticancer and anti-inflammatory activities of the essential oil from Ocimum kilimandscharicum

Author:
V.T. de Lima; M.C. Vieira; C.A.L. Kassuya; C.A.L. Cardoso; J.M. Alves; M.A. Foglio; J.E. de Carvalho; A.S.N. Formagio
Source:
Phytomedicine 2014 v.21 pp. 1298-1302
ISSN:
0944-7113
Subject:
2,2-diphenyl-1-picrylhydrazyl; Ocimum kilimandscharicum; animal ovaries; anti-inflammatory activity; antineoplastic activity; antioxidant activity; camphor; carrageenan; chemical composition; cineole; cytotoxicity; essential oils; free radical scavengers; gas chromatography-mass spectrometry; humans; hydrodistillation; leaves; leukocytes; limonene; mice; oils; oral administration; ovarian neoplasms; pleurisy; screening
Abstract:
... The essential oil from the leaves of Ocimum kilimandscharicum (EOOK), collected in Dourados-MS, was investigated for anticancer, anti-inflammatory and antioxidant activity and chemical composition.The essential oil was extracted by hydrodistillation, and the chemical composition was performed by gas chromatography–mass spectrometry. The essential oil was evaluated for free radical-scavenging activ ...
DOI:
10.1016/j.phymed.2014.07.004

34. Chemical composition, antimicrobial, antioxidant and antitumor activity of Thymus serpyllum L., Thymus algeriensis Boiss. and Reut and Thymus vulgaris L. essential oils

Author:
Miloš Nikolić; Jasmina Glamočlija; Isabel C.F.R. Ferreira; Ricardo C. Calhelha; Ângela Fernandes; Tatjana Marković; Dejan Marković; Abdulhamed Giweli; Marina Soković
Source:
Industrial crops and products 2014 v.52 pp. 183-190
ISSN:
0926-6690
Subject:
Thymus algeriensis; Thymus serpyllum; Thymus vulgaris; anti-infective properties; antineoplastic activity; antioxidant activity; antioxidants; antiseptics; cell culture; chemical composition; common cold; cosmetics; cystitis; essential oils; immune system; influenza; liver; medicinal plants; mouth diseases; oils; parasympatholytics; swine; thyme; thymol; toxicity
Abstract:
... Aromatic plant species of genus Thymus are important medicinal plants, highly recommended due to a range of therapeutic properties of their essential oils, commonly known as thyme oil: antirheumatic, antiseptic, antispasmodic, antimicrobial, cardiac, carminative, diuretic and expectorant. The oil is also beneficial in boosting the immune system and helps to fight colds, flu, infectious diseases an ...
DOI:
10.1016/j.indcrop.2013.10.006

35. Cladonia lichens and their major metabolites as possible natural antioxidant, antimicrobial and anticancer agents

Author:
Marijana Kosanić; Branislav Ranković; Tatjana Stanojković; Aleksandar Rančić; Nedeljko Manojlović
Source:
Lebensmittel-Wissenschaft + Technologie 2014 v.59 no.1 pp. 518-525
ISSN:
0023-6438
Subject:
Cladonia rangiferina; acetone; anti-infective properties; antineoplastic activity; antineoplastic agents; antioxidant activity; colorectal neoplasms; free radical scavengers; inhibitory concentration 50; lichens; melanoma; metabolites; minimum inhibitory concentration; pyrocatechol; rutin; superoxide anion
Abstract:
... The aim of this study is to investigate in vitro antioxidant, antimicrobial, and anticancer activities of the acetone extracts of the lichens Cladonia furcata, Cladonia pyxidata and Cladonia rangiferina and their atranorin and fumarprotocetraric acid constituents. Antioxidant activity was evaluated by free radical scavenging, superoxide anion radical scavenging, reducing power, and determination o ...
DOI:
10.1016/j.lwt.2014.04.047

36. Cytotoxic and antioxidant properties of active principals isolated from water hyacinth against four cancer cells lines

Author:
Ahmed M Aboul-Enein; Sanaa MM Shanab; Emad A Shalaby; Malak M Zahran; David A Lightfoot; Hany A El-Shemy
Source:
BMC complementary and alternative medicine 2014 v.14 no.1 pp. 397
ISSN:
1472-6882
Subject:
2,2-diphenyl-1-picrylhydrazyl; DNA fragmentation; Eichhornia crassipes; air drying; alkaloids; alternative medicine; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; cleaning; cytotoxicity; drainage channels; ethyl acetate; hexane; human cell lines; macrophytes; magnetism; methanol; neoplasm cells; neoplasms; river deltas; silica gel; spectroscopy; terpenoids; Egypt
Abstract:
... BACKGROUND: Eichhornia crassipes (Mart) solms is an invasive macrophyte causing serious problems to the network of irrigation and drainage canals in the Nile Delta region. The present study aim to evaluate the potential anticancer and antioxidant activities of Eichhornia crassipes crude extract and its pure compounds. METHODS: The macrophyte was collected from El-Zomor canal, River Nile (Egypt), c ...
DOI:
10.1186/1472-6882-14-397
PubMed:
25315352
PubMed Central:
PMC4213547

37. Effect of high hydrostatic pressure (HHP) treatment on flavor, physicochemical properties and biological functionalities of garlic

Author:
Kyung Won Kim; Young-Teck Kim; Miryung Kim; Bong-Soo Noh; Won-Seok Choi
Source:
Lebensmittel-Wissenschaft + Technologie 2014 v.55 no.1 pp. 347-354
ISSN:
0023-6438
Subject:
alliin lyase; antineoplastic activity; antioxidant activity; cohesion; color; flavor; garlic; hardness; high pressure treatment; pH; value added
Abstract:
... The characterization of flavor, physicochemical properties and biological activities of garlic extracts prepared by high hydrostatic pressure (HHP) treatment (500 MPa) was conducted at various HHP reaction times and pH conditions. The evaluation of flavor revealed that HHP treated garlic samples in acidic condition (pH 1.8–3) were most effective to reduce the pungent flavor of garlic among all con ...
DOI:
10.1016/j.lwt.2013.08.027

38. Effects of partial desulfation on antioxidant and inhibition of DLD cancer cell of Ulva fasciata polysaccharide

Author:
Ping Shao; Yaping Pei; Zhongxian Fang; Peilong Sun
Source:
International journal of biological macromolecules 2014 v.65 pp. 307-313
ISSN:
0141-8130
Subject:
Ulva; antineoplastic activity; antioxidant activity; antioxidants; desulfurization; macroalgae; molecular weight; neoplasm cells; neoplasms; polysaccharides; sulfates; ultrafiltration; uronic acids; China
Abstract:
... Ulva fasciata belonging to the family Ulvaceae, commonly known as ‘sea lettuce’, is an abundantly growing green seaweed in coastal seashore of South China. Three different molecular weight sulfated polysaccharides (UFP1, UFP2 and UFP3) were extracted and separated from U. fasciata by hot water extraction and ultrafiltration. The three native UFP fractions had partial desulfurization by solvolytic ...
DOI:
10.1016/j.ijbiomac.2014.01.043

39. Elucidation and biological activities of a new polysaccharide from cultured Cordyceps militaris

Author:
Yongshuai Jing; Xinlu Cui; Zhiyan Chen; Lijiao Huang; Liyan Song; Ting Liu; Wenjie Lv; Rongmin Yu
Source:
Carbohydrate polymers 2014 v.102 pp. 288-296
ISSN:
0144-8617
Subject:
Cordyceps militaris; antineoplastic activity; antioxidant activity; antioxidants; cytotoxicity; in vitro studies; inhibitory concentration 50; mice; molecular weight; polysaccharides; scanning electron microscopes; scanning electron microscopy; splenocytes; ultrastructure
Abstract:
... A novel low-molecular-weight polysaccharide (CMP-1) with antioxidant, immunostimulatory and antitumor activities was isolated from the cultured Cordyceps militaris. The structure of CMP-1 was elucidated by a combination of physicochemical and instrumental analyses, and its average molecular weight was 4.3kDa. The backbone of CMP-1 was composed of (1→4)-linked α-d-glucopyranosyl, (1→6)-linked β-d-g ...
DOI:
10.1016/j.carbpol.2013.11.061

40. Evaluation of Cytotoxic Compounds from Calligonum comosum L. Growing in Egypt

Author:
Farid A. Badria; Madiha Ameen; Mohamed R. Akl
Source:
Zeitschrift für Naturforschung 2014 v.62 no.9-10 pp. 656-660
ISSN:
1865-7125
Subject:
Artemia; Calligonum; antineoplastic activity; antioxidant activity; antioxidants; ascites; catechin; cytotoxicity; ethyl acetate; isoquercitrin; methylene chloride; petroleum; quercitrin; Egypt
Abstract:
... Calligonum comosum (Polygonaceae), an Egyptian desert plant, was extracted and fractionated using petroleum ether, methylene chloride, and ethyl acetate. The total methanolic extract and other fractions were tested for their anticancer activity using Ehrlich ascites, brine shrimp and antioxidant assays. Ethyl acetate fraction proved to be the most active in all assays. Eight compounds were isolate ...
DOI:
10.1515/znc-2007-9-1005

41. Extraction optimization and bioactivities of an extracellular polysaccharide produced by Aspergillus fumigatus

Author:
Xianchun Jin; Shiju Zhao
Source:
International journal of biological macromolecules 2014 v.68 pp. 13-17
ISSN:
0141-8130
Subject:
Aspergillus fumigatus; antineoplastic activity; antioxidant activity; arabinose; ethanol; glucose; hydroxyl radicals; molecular weight; pH; polysaccharides; response surface methodology; rice straw; sodium hydroxide; superoxide anion; xylose
Abstract:
... Aspergillus fumigatus produces an extracellular polysaccharide, AFEPS, when grew in NaOH solution pretreated rice-straw medium. A three-level, three-factor Box–Behnken design (BBD) response surface methodology (RSM) was applied to optimize the extraction parameters of AFEPS. RSM analysis indicated good correspondence between experimental and predicted values. The optimal conditions for polysacchar ...
DOI:
10.1016/j.ijbiomac.2014.04.024

42. Flavonoid concentrations and bioactivity of flavonoid extracts from 19 species of ferns from China

Author:
Xian Xia; Jianguo Cao; Yunxia Zheng; Quanxi Wang; Jianbo Xiao
Source:
Industrial crops and products 2014 v.58 pp. 91-98
ISSN:
0926-6690
Subject:
Davallia; Odontosoria chinensis; Selaginella; acetylcholinesterase; antineoplastic activity; antioxidant activity; ferns and fern allies; flavonoids; free radical scavengers; medicinal plants; phytopharmaceuticals; superoxide anion; China
Abstract:
... Ferns are famous traditional medicinal plants and 300 fern species have been used as phytomedicines by Southwestern of China. However, there is little information on the phytochemicals and pharmacological characteristics of most fern species. The total flavonoid concentrations, antioxidant activity, anticancer activity, and acetylcholinesterase inhibition of extracts from 19 species of ferns were ...
DOI:
10.1016/j.indcrop.2014.04.005

43. Fruit-derived phenolic compounds and pancreatic cancer: Perspectives from Australian native fruits

Author:
Q.V. Vuong; S. Hirun; P.A. Phillips; T.L.K. Chuen; M.C. Bowyer; C.D. Goldsmith; C.J. Scarlett
Source:
Journal of ethnopharmacology 2014 v.152 no.2 pp. 227-242
ISSN:
0378-8741
Subject:
antineoplastic activity; antineoplastic agents; antioxidant activity; bioactive compounds; carcinogenesis; databases; flora; foods; fruits; mechanism of action; pancreatic neoplasms; polyphenols; therapeutics; traditional medicine
Abstract:
... Pancreatic cancer is a devastating cancer that presents late, is rapidly progressive and has current therapeutics with only limited efficacy. Bioactive compounds are ubiquitously present in fruits and numerous studies in vitro are addressing the activity of these compounds against pancreatic cancer, thus studies of specific bioactive compounds could lead to new anti-pancreatic cancer strategies. A ...
DOI:
10.1016/j.jep.2013.12.023

44. Gastroprotective effect of the traditional herbal medicine, Sipjeondaebo-tang water extract, against ethanol-induced gastric mucosal injury

Author:
Woo-Young Jeon; In-Sik Shin; Hyeun-Kyoo Shin; Mee-Young Lee
Source:
BMC complementary and alternative medicine 2014 v.14 no.1 pp. 373
ISSN:
1472-6882
Subject:
acute toxicity; adverse effects; alternative medicine; antineoplastic activity; antioxidant activity; body weight; catalase; enzyme activity; ethanol; gastric mucosa; glutathione; glutathione peroxidase; glutathione transferase; glutathione-disulfide reductase; hemorrhage; herbal medicines; hyperemia; immune response; malondialdehyde; oral administration; rats; superoxide dismutase
Abstract:
... BACKGROUND: Sipjeondaebo-tang, a traditional herbal medicine, has been reported to activate the immune response. Although, most research has focused on its anticancer activity. The purpose of this study was to determine whether Sipjeondaebo-tang exerts antioxidant activity against ethanol-induced gastric injury. METHODS: Gastric mucosal injury was induced by the oral administration of absolute eth ...
DOI:
10.1186/1472-6882-14-373
PubMed:
25280763
PubMed Central:
PMC4193290

45. Hispolon from Phellinus linteus possesses mediate caspases activation and induces human nasopharyngeal carcinomas cells apoptosis through ERK1/2, JNK1/2 and p38 MAPK pathway

Author:
Ming-Ju Hsieh; Su-Yu Chien; Ying-Erh Chou; Chih-Jung Chen; Judy Chen; Mu-Kuan Chen
Source:
Phytomedicine 2014 v.21 pp. 1746-1752
ISSN:
0944-7113
Subject:
Phellinus linteus; Western blotting; antineoplastic activity; antioxidant activity; apoptosis; carcinoma; caspase-3; cell proliferation; drug therapy; humans; mitogen-activated protein kinase; phenol; phosphorylation
Abstract:
... Hispolon, a phenol compound isolated from Phellinus linteus (PL), possesses anti-inflammatory, antiproliferative, and antioxidant effects. However, the effects of hispolon on human nasopharyngeal carcinomas have yet to be evaluated. Here, the molecular mechanism by which hispolon anticancer effects in human nasopharyngeal carcinomas cells was investigated. The results showed that hispolon signific ...
DOI:
10.1016/j.phymed.2014.07.013

46. Hydnocarpus: An ethnopharmacological, phytochemical and pharmacological review

Author:
Manas Ranjan Sahoo; S.P. Dhanabal; Atul N. Jadhav; Vishali Reddy; Ganesh Muguli; U.V. Babu; Paramesh Rangesh
Source:
Journal of ethnopharmacology 2014 v.154 no.1 pp. 17-25
ISSN:
0378-8741
Subject:
Ayurvedic medicine; Hydnocarpus pentandrus; Salicaceae; anti-infective agents; antineoplastic activity; antioxidant activity; constipation; fatty acids; flavonoids; hematologic diseases; homeopathic drugs; inflammation; leprosy; mechanism of action; microorganisms; multiple drug resistance; seed oils; seeds; skin diseases; sterols; therapeutics; triacylglycerols; China; India; Malaysia; Myanmar; Thailand
Abstract:
... The genus Hydnocarpus (Flacourtiaceae) includes forty species that are spread across the globe. In the Indian System of Medicine, Hydnocarpus pentandrus (Buch.-Ham.) Oken. is primarily used for treating leprosy and other skin disorders. It is known as “Chaulmoogra” and is also used to treat other indications including constipation, inflammation, blood disorders, and worm infestations. Various spec ...
DOI:
10.1016/j.jep.2014.03.029

47. Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation

Author:
Lijuan Sun; Cheng Luo; Jiankang Liu
Source:
Food & function 2014 v.5 no.8 pp. 1909-1914
ISSN:
2042-650X
Subject:
antineoplastic activity; antioxidant activity; apoptosis; catalase; cell viability; chemoprevention; colon; colorectal neoplasms; epithelium; extra-virgin olive oil; gene expression regulation; genes; humans; hydrogen peroxide; mitochondria; neoplasm cells; oxidative stress; phosphatidylinositol 3-kinase; superoxide dismutase
Abstract:
... Cancer cells are usually under higher levels of oxidative stress compared to normal cells. We hypothesized that the introduction of additional reactive oxygen species (ROS) or the suppression of antioxidant activity may selectively enhance cancer cell killing by generating oxidative agents through stress overload or stress sensitization. The aim of this work was to test whether hydroxytyrosol (HT) ...
DOI:
10.1039/c4fo00187g

48. Identification of flavonoids in litchi (Litchi chinensis Sonn.) leaf and evaluation of anticancer activities

Author:
Lingrong Wen; Dan Wu; Yueming Jiang; K. Nagendra Prasad; Sen Lin; Guoxiang Jiang; Jirui He; Mouming Zhao; Wei Luo; Bao Yang
Source:
Journal of functional foods 2014 v.6 pp. 555-563
ISSN:
1756-4646
Subject:
Bacillus thuringiensis; Escherichia coli; Litchi chinensis; Salmonella; Shigella dysenteriae; Staphylococcus aureus; anti-infective properties; antineoplastic activity; antioxidant activity; breast neoplasms; butylated hydroxytoluene; chromatography; epicatechin; hepatoma; humans; kaempferol; leaves; lung neoplasms; luteolin; mass spectrometry; nuclear magnetic resonance spectroscopy; procyanidins; rutin; uterine cervical neoplasms
Abstract:
... Six flavonoids, namely luteolin (1), epicatechin (2), kaempferol 3-O-β-glucoside (3), kaempferol 3-O-α-rhamnoside (4), procyanidin A2 (5) and rutin (6) were purified from the EtOAc-soluble extract of litchi leaf by column chromatography. Their structures were elucidated by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) evidences. Luteolin and kaempferol 3-O-α-rhamnoside w ...
DOI:
10.1016/j.jff.2013.11.022

49. Identification of sesquilignans in litchi (Litchi chinensis Sonn.) leaf and their anticancer activities

Author:
Lingrong Wen; Jirui He; Dan Wu; Yueming Jiang; K. Nagendra Prasad; Mouming Zhao; Sen Lin; Guoxiang Jiang; Wei Luo; Bao Yang
Source:
Journal of functional foods 2014 v.8 pp. 26-34
ISSN:
1756-4646
Subject:
Litchi chinensis; antineoplastic activity; antioxidant activity; butylated hydroxytoluene; chromatography; cytotoxicity; drugs; electrospray ionization mass spectrometry; glycosides; human cell lines; humans; leaves; lignans; median effective concentration; nasopharynx; neoplasm cells; neoplasms; nuclear magnetic resonance spectroscopy; spectral analysis; traditional medicine
Abstract:
... Litchi (Litchi chinensis Sonn.) is a well-known traditional medicine since ancient times. The crude extract of litchi leaf exhibited good bioactivity against cancer cells. In this work, three sesquilignans, ehletianol C (1), sesquipinsapol B (2) and sesquimarocanol B (3), and one lignan glycoside schizandriside (4) were isolated from the ethyl acetate-soluble extract of litchi leaf by column chrom ...
DOI:
10.1016/j.jff.2014.02.017

50. In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea

Author:
Xin Zhao; Qiang Wang; Guijie Li; Feng Chen; Yu Qian; Rui Wang
Source:
Journal of functional foods 2014 v.7 pp. 590-598
ISSN:
1756-4646
Subject:
2,2-diphenyl-1-picrylhydrazyl; Salmonella Typhimurium; anti-inflammatory activity; antineoplastic activity; antioxidant activity; apoptosis; carcinoma; caspase-3; caspase-9; free radical scavengers; gallic acid; gene expression; gene expression regulation; humans; hydroxyl radicals; inducible nitric oxide synthase; inflammation; kaempferol; quercetin; reverse transcriptase polymerase chain reaction; tea; tongue; transcription factor NF-kappa B
Abstract:
... The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) ag ...
DOI:
10.1016/j.jff.2013.12.026