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1. Effects of Calorie Restricted Diet on Oxidative/Antioxidative Status Biomarkers and Serum Fibroblast Growth Factor 21 Levels in Nonalcoholic Fatty Liver Disease Patients: A Randomized, Controlled Clinical Trial

Author:
Somayyeh Asghari; Mahsa Rezaei; Maryam Rafraf; Mahdiyeh Taghizadeh; Mohammad Asghari-Jafarabadi; Maryam Ebadi
Source:
Nutrients 2022 v.14 no.12 pp. -
ISSN:
2072-6643
Subject:
alanine transaminase; antioxidant activity; aspartate transaminase; biomarkers; blood serum; body mass index; clinical trials; erythrocytes; fatty liver; fibroblast growth factors; food intake; glutathione peroxidase; low calorie diet; malondialdehyde; oxidative stress; patients; physical activity; superoxide dismutase; waist circumference; weight loss
Abstract:
... Oxidative stress plays a fundamental role in the development and progression of nonalcoholic fatty liver disease (NAFLD). This study aimed to investigate the effects of a calorie-restricted (CR) diet on oxidative/anti-oxidative status in patients with NAFLD and the potential mediating role of fibroblast growth factor 21 (FGF-21) in this regard. This randomized, controlled clinical trial was carrie ...
DOI:
10.3390/nu14122509

2. Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70

Author:
Gabriela Ferreira Abud; Flavia Giolo De Carvalho; Gabriela Batitucci; Sofia Germano Travieso; Carlos Roberto Bueno Junior; Fernando Barbosa Junior; Julio Sergio Marchini; Ellen Cristini de Freitas
Source:
Nutrition 2022 v.101 pp. 111706
ISSN:
0899-9007
Subject:
antioxidant activity; antioxidant enzymes; biomarkers; body mass index; clinical trials; food consumption; glutathione-disulfide reductase; malondialdehyde; nutrition; oxidative stress; placebos; starch; superoxide dismutase; taurine; therapeutics
Abstract:
... Based on the antioxidant effects of taurine, which are capable of controlling oxidative stress in the aging process, the aim of this study was to investigate the effects of taurine supplementation on biomarkers of oxidative stress in women 55 to 70 y of age. A double-blind study was conducted with 24 women (61.4 ± 4.2 y, body mass index 31.4 ± 5.1 kg/m²). The participants were randomly assigned to ...
DOI:
10.1016/j.nut.2022.111706

3. Association of measures of body fat with serum alpha-tocopherol and its metabolites in middle-aged individuals

Author:
Fleur L. Meulmeester; Jiao Luo; Leon G. Martens; Nadia Ashrafi; Renée de Mutsert; Dennis O. Mook-Kanamori; Hildo J. Lamb; Frits R. Rosendaal; Ko Willems van Dijk; Kevin Mills; Diana van Heemst; Raymond Noordam
Source:
Nutrition, metabolism, and cardiovascular diseases 2021 v.31 no.8 pp. 2407-2415
ISSN:
0939-4753
Subject:
abdominal fat; adipose tissue; alpha-tocopherol; antioxidant activity; blood serum; body mass index; cross-sectional studies; epidemiology; hydroquinone; liquid chromatography; magnetism; metabolism; metabolites; nutrition; obesity; oxidation; regression analysis; urine; Netherlands
Abstract:
... The accumulation of fat increases the formation of lipid peroxides, which are partly scavenged by alpha-tocopherol (α-TOH). Here, we aimed to investigate the associations between different measures of (abdominal) fat and levels of urinary α-TOH metabolites in middle-aged individuals.In this cross-sectional analysis in the Netherlands Epidemiology of Obesity study (N = 511, 53% women; mean [SD] age ...
DOI:
10.1016/j.numecd.2021.05.001

4. Interaction between Apo A-II -265T>C polymorphism and dietary total antioxidant capacity on some anthropometric indices and serum lipid profile in patients with type 2 diabetes mellitus

Author:
Banafsheh Jafari Azad; Mehdi Yaseri; Elnaz Daneshzad; Fariba Koohdani
Source:
Journal of nutritional science v.10 pp. e9
ISSN:
2048-6790
Subject:
analysis of covariance; antioxidant activity; atherosclerosis; blood lipids; body mass index; cholesterol; cross-sectional studies; food frequency questionnaires; homozygosity; lipid composition; low density lipoprotein; models; noninsulin-dependent diabetes mellitus; nutrition-genotype interaction; risk; triacylglycerols; waist circumference
Abstract:
... The present study aimed to investigate the interaction of Apo A-II polymorphism and dietary total antioxidant capacity (DTAC) with lipid profile and anthropometric markers in patients with type 2 diabetes (T2DM) that are at risk for atherosclerosis. This cross-sectional study was conducted on 778 patients with T2DM (35–65 years). Dietary intakes were assessed by a 147-item food frequency questionn ...
DOI:
10.1017/jns.2020.61

5. Nutritional status and birth outcomes among pregnant adolescents in Ashanti Region, Ghana

Author:
Linda Afriyie Gyimah; Reginald Adjetey Annan; Charles Apprey; Odeafo Asamoah-Boakye; Linda Nana Esi Aduku; Wisdom Azanu; Herman E. Lutterodt; Anthony Kwaku Edusei
Source:
Human nutrition & metabolism 2021 v.26 pp. 200130
ISSN:
2666-1497
Subject:
C-reactive protein; anemia; antioxidant activity; arm circumference; blood serum; body mass index; calcium; cohort studies; confidence interval; diet recall; dietary fiber; energy; ferritin; fetus; folic acid; hemoglobin; human nutrition; iron; low birth weight; metabolism; odds ratio; prealbumin; pregnancy; premature birth; prenatal care; protoporphyrin; riboflavin; thiamin; vitamin A; zinc; Ghana
Abstract:
... Inadequate nutrition during pregnancy can lead to adverse birth outcomes, and more importantly for pregnant adolescents as they require nutrients to meet their needs for their growth and the fetus. The study examined the relationship between nutritional status and birth outcomes among Ghanaian pregnant adolescents in selected districts of the Ashanti Region, Ghana. In this prospective cohort study ...
DOI:
10.1016/j.hnm.2021.200130

6. Association of dietary total antioxidant capacity to anthropometry in healthy women: A cross-sectional study

Author:
Hadis Mozaffari; Elnaz Daneshzad; Bagher Larijani; Pamela J. Surkan; Leila Azadbakht
Source:
Nutrition 2020 v.69 pp. 110577
ISSN:
0899-9007
Subject:
antioxidant activity; body mass index; cross-sectional studies; females; food frequency questionnaires; food intake; obesity; pathogenesis; reactive oxygen species; waist circumference; women
Abstract:
... Reactive oxygen species level is a fundamental component in the pathogenesis of obesity that might be reduced by dietary antioxidants. Measurement of dietary total antioxidant capacity (DTAC) is regarded as a new holistic dietary index. Given the limited research on DTAC, the aim of this study was to examine the association of DTAC with obesity-related features in women.The present cross-sectional ...
DOI:
10.1016/j.nut.2019.110577

7. Concurrent alteration in inflammatory biomarker gene expression and oxidative stress: how aerobic training and vitamin D improve T2DM

Author:
Rastegar Hoseini; Hiwa Ahmed Rahim; Jalal Khdhr Ahmed
Source:
BMC complementary medicine and therapies 2022 v.22 no.1 pp. 165
ISSN:
2662-7671
Subject:
C-reactive protein; albumins; alternative medicine; analysis of variance; antioxidant activity; antioxidants; biomarkers; blood glucose; blood serum; body mass index; catalase; gene expression; genes; glutathione; glutathione peroxidase; heart rate; homeostasis; inflammation; insulin; insulin resistance; interleukin-1beta; interleukin-4; malondialdehyde; mitogen-activated protein kinase; nitrites; noninsulin-dependent diabetes mellitus; oxidative stress; peroxisome proliferator-activated receptor gamma; placebos; superoxide dismutase; t-test; transcription factor NF-kappa B; tumor necrosis factor-alpha; vitamin D
Abstract:
... BACKGROUND: Vitamin D (Vit D) supplementation and Aerobic Training (AT) exert several beneficial effects such as antioxidant and anti-inflammatory actions. The literature on the effects of AT and Vit D supplementation on the oxidative stress biomarkers and gene expression of inflammatory cytokines in patients with Type 2 Diabetes Mellitus (T2DM) is limited. The present study aimed to examine the e ...
DOI:
10.1186/s12906-022-03645-7

8. Evaluating the effects of dark chocolate formulated with micro‐encapsulated fermented garlic extract on cardio‐metabolic indices in hypertensive patients: A crossover, triple‐blind placebo‐controlled randomized clinical trial

Author:
Salman Mohammadi; Seyed Mohammad Mazloomi; Mehrdad Niakousari; Zohreh Ghaem Far; Amir Azadi; Saeed Yousefinejad; Peyman Jafari; Shiva Faghih
Source:
Phytotherapy research 2022 v.36 no.4 pp. 1785-1796
ISSN:
0951-418X
Subject:
C-reactive protein; antioxidant activity; blood pressure; blood serum; body mass index; body weight; chocolate; cholesterol; dose response; fermentation; garlic; high density lipoprotein; homocysteine; lipid composition; low density lipoprotein; malondialdehyde; microencapsulation; oxidative stress; phytotherapy; placebos; randomized clinical trials; research; very low density lipoprotein; waist circumference
Abstract:
... This study aimed to investigate the health‐related effects of microencapsulated fermented garlic extract (FGE) containing dark chocolate in hypertensive adults. For this purpose, 36 hypertensive adults (15 males vs. 21 females) were randomized to receive the FGE (5 g/day) dark chocolate containing 650 mg of FGE powder or the placebo. Intervention periods lasted for 6 weeks and were separated by a ...
DOI:
10.1002/ptr.7421

9. Impact of Weight Loss on the Total Antioxidant/Oxidant Potential in Patients with Morbid Obesity—A Longitudinal Study

Author:
Barbara Choromańska; Piotr Myśliwiec; Magdalena Łuba; Piotr Wojskowicz; Hanna Myśliwiec; Katarzyna Choromańska; Małgorzata Żendzian-Piotrowska; Jacek Dadan; Anna Zalewska; Mateusz Maciejczyk
Source:
Antioxidants 2020 v.9 no.5 pp. -
ISSN:
2076-3921
Subject:
antioxidant activity; antioxidants; bariatric surgery; biomarkers; blood serum; body mass index; disease diagnosis; insulin; longitudinal studies; metabolic syndrome; obesity; oxidants; uric acid; waist-to-hip ratio; weight loss
Abstract:
... The assessment of total antioxidant activity seems to have a higher diagnostic value than the evaluation of individual antioxidants separately. Therefore, this is the first study to assess the total antioxidant/oxidant status in morbidly obese patients undergoing bariatric surgery. The study involved 60 patients with Class 3 obesity (BMI > 40 kg/m²) divided into two equal subgroups: morbidly obese ...
DOI:
10.3390/antiox9050376

10. Intradialytic Cardiovascular Exercise Training Alters Redox Status, Reduces Inflammation and Improves Physical Performance in Patients with Chronic Kidney Disease

Author:
Apostolos Sovatzidis; Athanasios Chatzinikolaou; Ioannis G. Fatouros; Stylianos Panagoutsos; Dimitrios Draganidis; Eirini Nikolaidou; Alexandra Avloniti; Yiannis Michailidis; Ioannis Mantzouridis; Alexios Batrakoulis; Ploumis Pasadakis; Vassilis Vargemezis
Source:
Antioxidants 2020 v.9 no.9 pp. -
ISSN:
2076-3921
Subject:
C-reactive protein; antioxidant activity; antioxidants; body composition; body mass index; catalase; education programs; exercise; females; glutathione; height; hemodialysis; inflammation; kidney diseases; males; mass; oxygen consumption; patients; quality of life; thiobarbituric acid-reactive substances
Abstract:
... Redox status (RS) perturbations and inflammation are fundamental features of chronic kidney disease (CKD) that are substantially exacerbated in end-stage renal disease (ESRD). This study aimed at investigating the efficacy of a 6-month intradialytic exercise training program on RS, inflammation and physical performance in patients with ESRD. Twenty hemodialysis (HD) patients (17 males, three femal ...
DOI:
10.3390/antiox9090868

11. Satiety, glycemic profiles, total antioxidant capacity, and postprandial glycemic responses to different sugars in healthy Malaysian adults

Author:
Azrina Azlan; Samarghand Ebadi; Barakatun Nisak Mohd Yusof; Nur Maziah Hanum Othman; David Kannar; Sharmin Sultana; Zhafarina Mahmood
Source:
Nutrition 2022 v.97 pp. 111551
ISSN:
0899-9007
Subject:
antioxidant activity; antioxidants; blood glucose; body mass index; brown sugar; c-peptide; glucagon; glucagon-like peptide 1; glucose; glycemic effect; glycemic index; leptin; nutrition; satiety; sucrose
Abstract:
... We investigated a low-glycemic index (GI), minimally refined brown sugar (MRBS) that retains a consistent amount of antioxidant polyphenols. This study aimed to determine whether MRBS has a lower postprandial glycemic response and GI value compared with other types of refined sugar (RS). Low glycemic response foods are also reported to increase satiety. Accordingly, we also evaluated satiety profi ...
DOI:
10.1016/j.nut.2021.111551

12. The Effects of Probiotic Supplementation on Clinical Symptom, Weight Loss, Glycemic Control, Lipid and Hormonal Profiles, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis of Randomized Controlled Trials

Author:
Reza Tabrizi; Vahidreza Ostadmohammadi; Maryam Akbari; Kamran B. Lankarani; Sina Vakili; Payam Peymani; Maryam Karamali; Fariba Kolahdooz; Zatollah Asemi
Source:
Probiotics and antimicrobial proteins 2022 v.14 no.1 pp. 1-14
ISSN:
1867-1306
Subject:
C-reactive protein; antioxidant activity; biomarkers; blood glucose; body mass index; confidence interval; glutathione; glycemic control; high density lipoprotein cholesterol; inflammation; insulin; insulin resistance; malondialdehyde; meta-analysis; models; nitric oxide; oxidative stress; polycystic ovary syndrome; prasterone; probiotics; signs and symptoms (animals and humans); systematic review; testosterone; weight loss
Abstract:
... The purpose of this systematic review and meta-analysis of randomized controlled trials (RCTs) is to determine the effectiveness of probiotic supplementation on clinical symptoms, weight loss, glycemic control, lipid and hormonal profiles, and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome (PCOS). Eligible studies were systematically searched from Cochrane ...
DOI:
10.1007/s12602-019-09559-0

13. The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease

Author:
Alireza Farrokhian; Mina Mahmoodian; Fereshteh Bahmani; Elaheh Amirani; Rana Shafabakhsh; Zatollah Asemi
Source:
Biological trace element research 2020 v.194 no.2 pp. 313-320
ISSN:
0163-4984
Subject:
C-reactive protein; antioxidant activity; blood serum; body mass index; body weight; chromium; coronary disease; diastolic blood pressure; fasting; glucose; insulin; insulin resistance; malondialdehyde; noninsulin-dependent diabetes mellitus; patients; placebos; randomized clinical trials
Abstract:
... This investigation was conducted to determine the effects of chromium supplementation on metabolic status in diabetic patients with coronary heart disease (CHD). This randomized, double-blind, placebo-controlled trial was performed in 64 diabetic patients with CHD between October 2017 and January 2018. Patients were randomly divided into two groups to obtain either 200 μg chromium (n = 32) or plac ...
DOI:
10.1007/s12011-019-01783-7

14. Total Dietary Antioxidant Capacity and Longitudinal Trajectories of Body Composition

Author:
Niels van der Schaft; Katerina Trajanoska; Fernando Rivadeneira; M. Arfan Ikram; Josje D. Schoufour; Trudy Voortman
Source:
Antioxidants 2020 v.9 no.8 pp. -
ISSN:
2076-3921
Subject:
Dietary Guidelines; antioxidant activity; antioxidants; body fat; body mass index; data analysis; dual-energy X-ray absorptiometry; elderly; fat mass index; food frequency questionnaires; food intake; lean body mass; longitudinal studies; muscle strength; obesity; regression analysis; sarcopenia; standard deviation; statistical models
Abstract:
... Although there is some evidence that total dietary antioxidant capacity (TDAC) is inversely associated with the presence of obesity, no longitudinal studies have been performed investigating the effect of TDAC on comprehensive measures of body composition over time. In this study, we included 4595 middle-aged and elderly participants from the Rotterdam Study, a population-based cohort. We estimate ...
DOI:
10.3390/antiox9080728

15. Urinary levels of environmental phenols and parabens and antioxidant enzyme activity in the blood of women

Author:
Anna Z. Pollack; Sunni L. Mumford; Jenna R. Krall; Andrea Carmichael; Victoria C. Andriessen; Kurunthachalam Kannan; Enrique F. Schisterman
Source:
Environmental research 2020 v.186 pp. 109507
ISSN:
0013-9351
Subject:
2,4,6-trichlorophenol; 2,4-dichlorophenol; antioxidant activity; antioxidant biomarkers; antioxidant enzymes; blood plasma; body mass index; creatinine; enzyme activity; erythrocytes; glutathione peroxidase; glutathione-disulfide reductase; humans; lifestyle; oxidative stress; phenol; principal component analysis; probability; statistical models; superoxide dismutase; urine; women
Abstract:
... The balance between oxidative stress and antioxidant enzymes is one biological mechanism by which environmental and lifestyle exposures affect health outcomes. Yet, no studies have examined the relationship between environmental phenolic compounds and parabens or their mixtures in relation to antioxidant enzyme activity in women of reproductive age.Sixteen environmental phenols and parabens were m ...
DOI:
10.1016/j.envres.2020.109507

16. Among the water-soluble vitamins, dietary intakes of vitamins C, B₂ and folate are associated with the reduced risk of diabetes in Japanese women but not men

Author:
Ehab S. Eshak; Hiroyasu Iso; Isao Muraki; Akiko Tamakoshi
Source:
British journal of nutrition 2019 v.121 no.12 pp. 1357-1364
ISSN:
1475-2662
Subject:
Japanese people; antioxidant activity; ascorbic acid; body mass index; folic acid; food intake; men; noninsulin-dependent diabetes mellitus; prospective studies; protective effect; pyridoxine; regression analysis; riboflavin; risk; risk reduction; smoking (habit); thiamin; women
Abstract:
... Recent studies have shown that micronutrients are involved in the pathology of type 2 diabetes. Antioxidant effects of vitamins C and B₂ and homocysteine-lowering effects of vitamins B₆, folate and B₁₂ may have protective roles. However, a few reports have investigated the association between dietary water-soluble vitamin intakes and risk of diabetes. In a prospective study encompassing 19 168 hea ...
DOI:
10.1017/S000711451900062X

17. Assessment of micronutrients in a 12-wk ketogenic diet in obese adults

Author:
Saša Kenig; Ana Petelin; Tamara Poklar Vatovec; Nina Mohorko; Zala Jenko-Pražnikar
Source:
Nutrition 2019 v.67-68 pp. 110522
ISSN:
0899-9007
Subject:
adults; antioxidant activity; blood serum; body mass index; calcium; dairy consumption; fat intake; foods; iron; ketogenic diet; legumes; magnesium; minerals; phosphates; phosphorus; potassium; unsaturated fatty acids; water-soluble vitamins
Abstract:
... A 12-wk ketogenic diet was found to have many beneficial effects in healthy obese adults, but it is not clear if the supply of micronutrients is adequate.In 35 adult individuals with body mass index >30, the intakes of minerals and their serum levels were analyzed at baseline and at weeks 4 and 12 of the ketogenic diet intervention. The intake of vitamins and serum antioxidative potential were als ...
DOI:
10.1016/j.nut.2019.06.003

18. Association of Metabolically Healthy and Unhealthy Obesity Phenotypes with Oxidative Stress Parameters and Telomere Length in Healthy Young Adult Men. Analysis of the MAGNETIC Study

Author:
Mateusz Lejawa; Kamila Osadnik; Tadeusz Osadnik; Natalia Pawlas
Source:
Antioxidants 2021 v.10 no.1 pp. -
ISSN:
2076-3921
Subject:
antioxidant activity; antioxidants; blood serum; body mass index; laboratories; lead; length; magnetism; men; metabolic syndrome; obesity; oxidation; oxidative stress; patients; phenotype; quantitative polymerase chain reaction; telomeres; young adults
Abstract:
... Obesity is a significant factor related to metabolic disturbances that can lead to metabolic syndrome (MetS). Metabolic dysregulation causes oxidative stress, which affects telomere structure. The current study aimed to evaluate the relationships between telomere length, oxidative stress and the metabolically healthy and unhealthy phenotypes in healthy young men. Ninety-eight participants were inc ...
DOI:
10.3390/antiox10010093

19. BMI-based Prenatal Vitamins to Ameliorate Oxidative Stress in Obese Pregnant Women: A Randomized Controlled Trial (P11-135-19)

Author:
Sarbattama Sen; Mary Herlihy; Michele Hacker; Thomas Mcelrath; Sara Cherkerzian; Emily Oken; Simin Meydani
Source:
Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
ISSN:
2475-2991
Subject:
antioxidant activity; antioxidants; biomarkers; blood; body mass index; child health; childhood; demography; dietary supplements; folic acid; human development; inflammation; interleukin-6; nutrients; obesity; oxidative stress; pregnancy; pregnant women; pyridoxine; randomized clinical trials; regression analysis; urine
Abstract:
... Obesity during pregnancy is associated with inflammation and oxidative stress and concomitant depletion of nutritional antioxidant defenses, which may be implicated in adverse perinatal and long-term childhood outcomes. The objective of this study is to determine whether providing a BMI-based prenatal vitamin (BMI-PNV) to pregnant women with obesity would raise concentrations of key antioxidant vi ...
DOI:
10.1093/cdn/nzz048.P11-135-19

20. Cocaine Use, Oxidative Stress and Inflammation Among People Living with HIV in the MASH Cohort in Miami (P19-002-19)

Author:
Alhanoof Alohaly; Adriana Campa; Leslie Seminario; Marianna Baum
Source:
Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
ISSN:
2475-2991
Subject:
C-reactive protein; DNA damage; HIV infections; Human immunodeficiency virus; adults; amino acids; antioxidant activity; antioxidants; antiretroviral agents; at-risk population; bioelectrical impedance; biomarkers; blood; body fat; body mass index; cocaine; cross-sectional studies; dietary supplements; glutathione; inflammation; males; overweight; oxidation; oxidative stress; therapeutics; viral load
Abstract:
... HIV infection and cocaine use contribute to oxidative stress; persistent oxidative stress leads to rapid rates of glutathione (GSH) consumption. GSH is an abundant intracellular antioxidant and is synthesized from its precursor amino acids. HIV promotes changes in the components of the antioxidant defense system, resulting in GSH depletion and may cause DNA damage, and is associated with chronic i ...
DOI:
10.1093/cdn/nzz049.P19-002-19